| Year |
Citation |
Score |
| 2024 |
Randall KL, Flesch IEA, Mei Y, Miosge LA, Aye R, Yu Z, Domaschenz H, Hollett NA, Russell TA, Stefanovic T, Wong YC, Seneviratne S, Ballard F, Hernandez Gallardo R, Croft SN, ... Goodnow CC, et al. DOCK2-deficiency causes defects in anti-viral T cell responses and impaired control of herpes simplex virus infection. The Journal of Infectious Diseases. PMID 38366567 DOI: 10.1093/infdis/jiae077 |
0.307 |
|
| 2024 |
Mina ED, Jackson KJL, Crawford AJI, Faulks ML, Pathmanandavel K, Acquarola N, O'Sullivan M, Kerre T, Naesens L, Claes K, Goodnow CC, Haerynck F, Kracker S, Meyts I, D'Orsogna LJ, et al. A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome. Journal of Clinical Immunology. 44: 66. PMID 38363477 DOI: 10.1007/s10875-024-01665-1 |
0.345 |
|
| 2023 |
Masle-Farquhar E, Jeelall Y, White J, Bier J, Deenick EK, Brink R, Horikawa K, Goodnow CC. gain-of-function mutation drives cell-autonomous accumulation of PD-1 ICOS activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells. Frontiers in Immunology. 14: 1095257. PMID 36960072 DOI: 10.3389/fimmu.2023.1095257 |
0.313 |
|
| 2022 |
Masle-Farquhar E, Jackson KJL, Peters TJ, Al-Eryani G, Singh M, Payne KJ, Rao G, Avery DT, Apps G, Kingham J, Jara CJ, Skvortsova K, Swarbrick A, Ma CS, Suan D, ... ... Goodnow CC, et al. STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D CD8 T cell dysregulation and accumulation. Immunity. PMID 36446385 DOI: 10.1016/j.immuni.2022.11.001 |
0.33 |
|
| 2022 |
Yang R, Avery DT, Jackson KJL, Ogishi M, Benhsaien I, Du L, Ye X, Han J, Rosain J, Peel JN, Alyanakian MA, Neven B, Winter S, Puel A, Boisson B, ... ... Goodnow CC, et al. Human T-bet governs the generation of a distinct subset of CD11cCD21 B cells. Science Immunology. 7: eabq3277. PMID 35867801 DOI: 10.1126/sciimmunol.abq3277 |
0.424 |
|
| 2022 |
Langley DB, Schofield P, Nevoltris D, Jackson J, Jackson KJL, Peters TJ, Burk M, Matthews JM, Basten A, Goodnow CC, van Nunen S, Reed JH, Christ D. Genetic and structural basis of the human anti-α-galactosyl antibody response. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123212119. PMID 35867757 DOI: 10.1073/pnas.2123212119 |
0.642 |
|
| 2022 |
Nüssing S, Miosge LA, Lee K, Olshansky M, Barugahare A, Roots CM, Sontani Y, Day EB, Koutsakos M, Kedzierska K, Goodnow CC, Russ BE, Daley SR, Turner SJ. SATB1 ensures appropriate transcriptional programs within naïve CD8 T cells. Immunology and Cell Biology. PMID 35713361 DOI: 10.1111/imcb.12566 |
0.313 |
|
| 2022 |
Masle-Farquhar E, Peters TJ, Miosge LA, Parish IA, Weigel C, Oakes CC, Reed JH, Goodnow CC. Uncontrolled CD21 age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint. Cell Reports. 38: 110259. PMID 35045301 DOI: 10.1016/j.celrep.2021.110259 |
0.415 |
|
| 2021 |
Zhang Z, Jara CJ, Singh M, Xu H, Goodnow CC, Jackson KJ, Reed JH. Human transitional and IgM low mature naïve B cells preserve permissive B cell receptors. Immunology and Cell Biology. PMID 33988890 DOI: 10.1111/imcb.12478 |
0.329 |
|
| 2021 |
Masle-Farquhar E, Russell A, Li Y, Zhu F, Rui L, Brink R, Goodnow CC. Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice. Plos One. 16: e0237830. PMID 33914737 DOI: 10.1371/journal.pone.0237830 |
0.342 |
|
| 2021 |
Boast B, Miosge LA, Kuehn HS, Cho V, Athanasopoulos V, McNamara HA, Sontani Y, Mei Y, Howard D, Sutton HJ, Omari SA, Yu Z, Nasreen M, Andrews TD, Cockburn IA, ... Goodnow CC, et al. A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 33658297 DOI: 10.4049/jimmunol.1901464 |
0.374 |
|
| 2020 |
Yabas M, Yazicioglu YF, Hoyne GF, Goodnow CC, Enders A. Loss of hnRNPLL-dependent splicing of Ptprc has no impact on B-cell development, activation and terminal differentiation into antibody-secreting cells. Immunology and Cell Biology. PMID 33331104 DOI: 10.1111/imcb.12433 |
0.442 |
|
| 2020 |
Burnett DL, Schofield P, Langley DB, Jackson J, Bourne K, Wilson E, Porebski BT, Buckle AM, Brink R, Goodnow CC, Christ D. Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proceedings of the National Academy of Sciences of the United States of America. PMID 32855302 DOI: 10.1073/Pnas.2005102117 |
0.394 |
|
| 2020 |
Singh M, Jackson KJL, Wang JJ, Schofield P, Field MA, Koppstein D, Peters TJ, Burnett DL, Rizzetto S, Nevoltris D, Masle-Farquhar E, Faulks ML, Russell A, Gokal D, Hanioka A, ... ... Goodnow CC, et al. Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. PMID 32059783 DOI: 10.1016/J.Cell.2020.01.029 |
0.422 |
|
| 2020 |
Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, ... ... Goodnow CC, et al. Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production. The Journal of Experimental Medicine. 217. PMID 31841125 DOI: 10.1084/Jem.20191336 |
0.528 |
|
| 2019 |
Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, ... ... Goodnow CC, et al. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science Immunology. 4. PMID 31757835 DOI: 10.1126/Sciimmunol.Aay6039 |
0.437 |
|
| 2019 |
Burnett DL, Reed JH, Christ D, Goodnow CC. Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity. Immunological Reviews. PMID 31556969 DOI: 10.1111/Imr.12808 |
0.484 |
|
| 2019 |
Siggs OM, Russell A, Singh-Grewal D, Wong M, Chan P, Craig ME, O'Loughlin T, Stormon M, Goodnow CC. Preponderance of Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif. Frontiers in Immunology. 10: 1544. PMID 31396201 DOI: 10.3389/Fimmu.2019.01544 |
0.338 |
|
| 2019 |
Singh M, Al-Eryani G, Carswell S, Ferguson JM, Blackburn J, Barton K, Roden D, Luciani F, Giang Phan T, Junankar S, Jackson K, Goodnow CC, Smith MA, Swarbrick A. High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nature Communications. 10: 3120. PMID 31311926 DOI: 10.1038/S41467-019-11049-4 |
0.4 |
|
| 2019 |
Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, Mirrashidi KM, Haley B, Watanabe C, Roose-Girma M, Modrusan Z, Kummerfeld S, Reja R, Zhang Y, Cho V, Andrews TD, ... ... Goodnow CC, et al. IRF2 transcriptionally induces expression for pyroptosis. Science Signaling. 12. PMID 31113851 DOI: 10.1126/Scisignal.Aax4917 |
0.312 |
|
| 2019 |
Policheni A, Horikawa K, Milla L, Kofler J, Bouillet P, Belz GT, O'Reilly LA, Goodnow CC, Strasser A, Gray DHD. CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally-induced FOXP3+ regulatory T cells. Immunology and Cell Biology. PMID 31087793 DOI: 10.1111/Imcb.12268 |
0.469 |
|
| 2019 |
Wirasinha RC, Chan A, Yap JY, Hu DY, Teh CE, Gray DHD, Goodnow CC, Daley SR. Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells. Cell Death and Differentiation. PMID 31019259 DOI: 10.1038/S41418-019-0331-8 |
0.437 |
|
| 2019 |
Moran I, Avery DT, Payne K, Lenthall H, Davies EG, Burns S, Ip W, Oleastro MM, Reisli I, Guner S, Keles S, Notarangelo L, Deenick EK, Goodnow CC, Zahra D, et al. B cell-intrinsic requirement for STK4 in humoral immunity in mice and humans. The Journal of Allergy and Clinical Immunology. PMID 30796983 DOI: 10.1016/J.Jaci.2019.02.010 |
0.438 |
|
| 2019 |
Singh M, Jackson K, Wang JJ, Schofield P, Field M, Peters T, Luciani F, Gordon T, Goodnow C, Reed JH. 241 Single cell genomics of self-reactive B cells reveals the evolution from benign to pathogenic autoantibody and strategies for early diagnosis and personalised treatment Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.241 |
0.46 |
|
| 2018 |
Schofield P, Vazquez-Lombardi R, Abdelatti M, Nevoltris D, Goodnow CC, Christ D, Reed JH. Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood. Methods in Molecular Biology (Clifton, N.J.). 1827: 287-309. PMID 30196503 DOI: 10.1007/978-1-4939-8648-4_15 |
0.397 |
|
| 2018 |
Wagle MV, Marchingo JM, Howitt J, Tan SS, Goodnow CC, Parish IA. The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8 T Cell Tolerance Checkpoint to High-Dose Antigen. Cell Reports. 24: 577-584. PMID 30021156 DOI: 10.1016/J.Celrep.2018.06.060 |
0.441 |
|
| 2018 |
Wirasinha RC, Singh M, Archer SK, Chan A, Harrison PF, Goodnow CC, Daley SR. αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors. Immunology and Cell Biology. PMID 29726044 DOI: 10.1111/Imcb.12047 |
0.445 |
|
| 2018 |
Rizzetto S, Koppstein DNP, Samir J, Singh M, Reed JH, Cai CH, Lloyd AR, Eltahla AA, Goodnow CC, Luciani F. B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle. Bioinformatics (Oxford, England). PMID 29659703 DOI: 10.1093/Bioinformatics/Bty203 |
0.419 |
|
| 2018 |
Burnett DL, Langley DB, Schofield P, Hermes JR, Chan TD, Jackson J, Bourne K, Reed JH, Patterson K, Porebski BT, Brink R, Christ D, Goodnow CC. Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. Science (New York, N.Y.). 360: 223-226. PMID 29650674 DOI: 10.1126/Science.Aao3859 |
0.451 |
|
| 2018 |
Alshekaili J, Chand R, Lee CE, Corley S, Kwong K, Papa I, Fulcher DA, Randall KL, Leiding JW, Ma CS, Wilkins MR, Uzel G, Goodnow CC, Vinuesa CG, Tangye SG, et al. STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles. Scientific Reports. 8: 3529. PMID 29476109 DOI: 10.1038/S41598-018-21389-8 |
0.36 |
|
| 2018 |
Yap JY, Wirasinha RC, Chan A, Howard DR, Goodnow CC, Daley SR. Indirect presentation in the thymus limits naïve and regulatory T cell differentiation by promoting deletion of self-reactive thymocytes. Immunology. PMID 29411880 DOI: 10.1111/Imm.12904 |
0.485 |
|
| 2017 |
Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, ... ... Goodnow CC, et al. A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation. Plos Genetics. 13: e1007072. PMID 29117179 DOI: 10.1371/Journal.Pgen.1007072 |
0.328 |
|
| 2017 |
Wang JQ, Jeelall YS, Humburg P, Batchelor EL, Kaya SM, Yoo HM, Goodnow CC, Horikawa K. Synergistic cooperation and crosstalk between MYD88(L265P) and mutations that dysregulate CD79B and surface IgM. The Journal of Experimental Medicine. PMID 28701369 DOI: 10.1084/Jem.20161454 |
0.41 |
|
| 2017 |
Burnett D, Parish I, Masle-Farquhar E, Brink R, Goodnow C. Murine LRBA-deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation. Immunology and Cell Biology. PMID 28611475 DOI: 10.1038/Icb.2017.50 |
0.504 |
|
| 2017 |
Miosge LA, Sontani Y, Chuah A, Horikawa K, Russell TA, Mei Y, Wagle MV, Howard DR, Enders A, Tscharke DC, Goodnow CC, Parish IA. Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607084 DOI: 10.1073/Pnas.1705795114 |
0.48 |
|
| 2017 |
Hu DY, Wirasinha RC, Goodnow CC, Daley SR. IL-2 prevents deletion of developing T-regulatory cells in the thymus. Cell Death and Differentiation. PMID 28362433 DOI: 10.1038/Cdd.2017.38 |
0.397 |
|
| 2016 |
Cho JH, Kim HO, Ju YJ, Kye YC, Lee GW, Lee SW, Yun CH, Bottini N, Webster K, Goodnow CC, Surh CD, King C, Sprent J. CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells. Nature Communications. 7: 13373. PMID 27841348 DOI: 10.1038/Ncomms13373 |
0.422 |
|
| 2016 |
Sabouri Z, Perotti S, Spierings E, Humburg P, Yabas M, Bergmann H, Horikawa K, Roots C, Lambe S, Young C, Andrews TD, Field M, Enders A, Reed JH, Goodnow CC. IgD attenuates the IgM-induced anergy response in transitional and mature B cells. Nature Communications. 7: 13381. PMID 27830696 DOI: 10.1038/Ncomms13381 |
0.484 |
|
| 2016 |
Koay HF, Gherardin NA, Enders A, Loh L, Mackay LK, Almeida CF, Russ BE, Nold-Petry CA, Nold MF, Bedoui S, Chen Z, Corbett AJ, Eckle SB, Meehan B, d'Udekem Y, ... ... Goodnow CC, et al. A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology. PMID 27668799 DOI: 10.1038/Ni.3565 |
0.451 |
|
| 2016 |
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. The Journal of Clinical Investigation. PMID 27599296 DOI: 10.1172/Jci85774 |
0.372 |
|
| 2016 |
Tangye SG, Pillay B, Randall KL, Avery DT, Phan TG, Gray P, Ziegler JB, Smart JM, Peake J, Arkwright PD, Hambleton S, Orange J, Goodnow CC, Uzel G, Casanova JL, et al. DOCK8-Deficient CD4(+) T Cells are Biased to a Th2 Effector Fate at the Expense of Th1 and Th17 Cells. The Journal of Allergy and Clinical Immunology. PMID 27554822 DOI: 10.1016/J.Jaci.2016.07.016 |
0.39 |
|
| 2016 |
Wang JQ, Beutler B, Goodnow CC, Horikawa K. Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo. Blood. PMID 27458005 DOI: 10.1182/Blood-2016-03-708065 |
0.372 |
|
| 2016 |
Reed JH, Jackson J, Christ D, Goodnow CC. Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization. The Journal of Experimental Medicine. 213: 1255-65. PMID 27298445 DOI: 10.1084/Jem.20151978 |
0.477 |
|
| 2016 |
Wu Z, Liang R, Ohnesorg T, Cho V, Lam W, Abhayaratna WP, Gatenby PA, Perera C, Zhang Y, Whittle B, Sinclair A, Goodnow CC, Field M, Andrews TD, Cook MC. Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion. Plos Genetics. 12: e1006067. PMID 27227454 DOI: 10.1371/Journal.Pgen.1006067 |
0.302 |
|
| 2016 |
Hu DY, Yap JY, Wirasinha RC, Howard DR, Goodnow CC, Daley SR. A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development. Immunology and Cell Biology. 94: 357-66. PMID 26510893 DOI: 10.1038/Icb.2015.95 |
0.325 |
|
| 2016 |
Godfrey D, Koay HF, Gherardin N, Enders A, Loh L, Chen Z, Corbett A, Eckle S, Meehan B, d'Udekem Y, Konstantinov I, Lappas M, Liu L, Goodnow C, Fairlie D, et al. Thymic precursors to the mucosal-associated invariant T cell lineage European Journal of Immunology. 46: 256-257. DOI: 10.1002/Eji.201670015 |
0.378 |
|
| 2015 |
Lim SL, Qu ZP, Kortschak RD, Lawrence DM, Geoghegan J, Hempfling AL, Bergmann M, Goodnow CC, Ormandy CJ, Wong L, Mann J, Scott HS, Jamsai D, Adelson DL, O'Bryan MK. HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse. Plos Genetics. 11: e1005620. PMID 26496356 DOI: 10.1371/Journal.Pgen.1005620 |
0.368 |
|
| 2015 |
Ramiscal RR, Parish IA, Lee-Young RS, Babon JJ, Blagih J, Pratama A, Martin J, Hawley N, Cappello JY, Nieto PF, Ellyard JI, Kershaw NJ, Sweet RA, Goodnow CC, Jones RG, et al. Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation. Elife. 4. PMID 26496200 DOI: 10.7554/Elife.08698 |
0.403 |
|
| 2015 |
Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT, Liu PS, Lill JR, Li H, Wu J, Kummerfeld S, ... ... Goodnow CC, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature. 526: 666-71. PMID 26375259 DOI: 10.1038/Nature15541 |
0.306 |
|
| 2015 |
Fuchs S, Rensing-Ehl A, Pannicke U, Lorenz MR, Fisch P, Jeelall Y, Rohr J, Speckmann C, Vraetz T, Farmand S, Schmitt-Graeff A, Krüger M, Strahm B, Henneke P, Enders A, ... ... Goodnow C, et al. Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency. Blood. 126: 1658-69. PMID 26289640 DOI: 10.1182/Blood-2015-03-631374 |
0.412 |
|
| 2015 |
Tangye SG, Brink R, Goodnow CC, Phan TG. SnapShot: Interactions between B Cells and T Cells. Cell. 162: 926-6.e1. PMID 26276638 DOI: 10.1016/J.Cell.2015.07.055 |
0.421 |
|
| 2015 |
Miosge LA, Field MA, Sontani Y, Cho V, Johnson S, Palkova A, Balakishnan B, Liang R, Zhang Y, Lyon S, Beutler B, Whittle B, Bertram EM, Enders A, Goodnow CC, et al. Comparison of predicted and actual consequences of missense mutations. Proceedings of the National Academy of Sciences of the United States of America. 112: E5189-98. PMID 26269570 DOI: 10.1073/Pnas.1511585112 |
0.302 |
|
| 2015 |
Rahimpour A, Koay HF, Enders A, Clanchy R, Eckle SB, Meehan B, Chen Z, Whittle B, Liu L, Fairlie DP, Goodnow CC, McCluskey J, Rossjohn J, Uldrich AP, Pellicci DG, et al. Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers. The Journal of Experimental Medicine. 212: 1095-108. PMID 26101265 DOI: 10.1084/Jem.20142110 |
0.435 |
|
| 2015 |
Flesch IE, Randall KL, Hollett NA, Di Law H, Miosge LA, Sontani Y, Goodnow CC, Tscharke DC. Delayed control of herpes simplex virus infection and impaired CD4(+) T-cell migration to the skin in mouse models of DOCK8 deficiency. Immunology and Cell Biology. 93: 517-21. PMID 25776845 DOI: 10.1038/Icb.2015.32 |
0.351 |
|
| 2015 |
Hillen KM, Gather R, Enders A, Pircher H, Aichele P, Fisch P, Blumenthal B, Schamel WW, Straub T, Goodnow CC, Ehl S. T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: implications for human immunodeficiency. Journal of Immunology (Baltimore, Md. : 1950). 194: 2725-34. PMID 25672755 DOI: 10.4049/Jimmunol.1400328 |
0.441 |
|
| 2015 |
Siggs OM, Miosge LA, Daley SR, Asquith K, Foster PS, Liston A, Goodnow CC. Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2587-95. PMID 25662996 DOI: 10.4049/Jimmunol.1400326 |
0.373 |
|
| 2015 |
Ramiscal RR, Parish IA, Lee-Young RS, Babon JJ, Blagih J, Pratama A, Martin J, Hawley N, Cappello JY, Nieto PF, Ellyard JI, Kershaw NJ, Sweet RA, Goodnow CC, Jones RG, et al. Author response: Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation Elife. DOI: 10.7554/Elife.08698.021 |
0.366 |
|
| 2015 |
Tangye SG, Brink R, Goodnow CC, Phan TG. SnapShot: Interactions between B Cells and T Cells Cell. 162: 926-926.e1. DOI: 10.1016/j.cell.2015.07.055 |
0.337 |
|
| 2014 |
Han BY, Wu S, Foo CS, Horton RM, Jenne CN, Watson SR, Whittle B, Goodnow CC, Cyster JG. Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment. Elife. 3. PMID 25343476 DOI: 10.7554/Elife.03549 |
0.434 |
|
| 2014 |
Lee CE, Fulcher DA, Whittle B, Chand R, Fewings N, Field M, Andrews D, Goodnow CC, Cook MC. Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100. Blood. 124: 2964-72. PMID 25237204 DOI: 10.1182/Blood-2014-06-578542 |
0.438 |
|
| 2014 |
Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, ... Goodnow CC, et al. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. Proceedings of the National Academy of Sciences of the United States of America. 111: E2567-75. PMID 24821781 DOI: 10.1073/Pnas.1406974111 |
0.462 |
|
| 2014 |
Enders A, Short A, Miosge LA, Bergmann H, Sontani Y, Bertram EM, Whittle B, Balakishnan B, Yoshida K, Sjollema G, Field MA, Andrews TD, Hagiwara H, Goodnow CC. Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 111: 4513-8. PMID 24616512 DOI: 10.1073/Pnas.1402739111 |
0.509 |
|
| 2014 |
Wang JQ, Jeelall YS, Beutler B, Horikawa K, Goodnow CC. Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance. The Journal of Experimental Medicine. 211: 413-26. PMID 24534189 DOI: 10.1084/Jem.20131424 |
0.39 |
|
| 2014 |
Altin JA, Daley SR, Howitt J, Rickards HJ, Batkin AK, Horikawa K, Prasad SJ, Nelms KA, Kumar S, Wu LC, Tan SS, Cook MC, Goodnow CC. Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 2067-74. PMID 24520172 DOI: 10.1073/Pnas.1322739111 |
0.508 |
|
| 2014 |
Bull KR, Mason T, Rimmer AJ, Crockford TL, Silver KL, Bouriez-Jones T, Hough TA, Chaudhry S, Roberts ISD, Goodnow CC, Cornall RJ. Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome Journal of Pathology. 233: 18-26. PMID 24293254 DOI: 10.1002/Path.4308 |
0.301 |
|
| 2014 |
Siggs OM, Yates AL, Schlenner S, Liston A, Lesage S, Goodnow CC. A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction Immunology. 141: 587-595. PMID 24266404 DOI: 10.1111/Imm.12220 |
0.423 |
|
| 2014 |
Han BY, Wu S, Foo C, Horton RM, Jenne CN, Watson SR, Whittle B, Goodnow CC, Cyster JG. Author response: Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment Elife. DOI: 10.7554/Elife.03549.031 |
0.355 |
|
| 2014 |
Talaulikar D, Jeelall Y, Ziolkowski A, Cook M, Jain S, Andrews D, Field M, Goodnow C. Genetics of Disease Progression in Diffuse Large B-Cell Lymphoma: Clonal Selection and Acquisition of Newly Acquired Somatic Mutations at Relapse Blood. 124: 3038-3038. DOI: 10.1182/Blood.V124.21.3038.3038 |
0.342 |
|
| 2013 |
Daley SR, Coakley KM, Hu DY, Randall KL, Jenne CN, Limnander A, Myers DR, Polakos NK, Enders A, Roots C, Balakishnan B, Miosge LA, Sjollema G, Bertram EM, Field MA, ... ... Goodnow CC, et al. Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies. Elife. 2: e01020. PMID 24336796 DOI: 10.7554/Elife.01020 |
0.439 |
|
| 2013 |
Jamsai D, Clark BJ, Smith SJ, Whittle B, Goodnow CC, Ormandy CJ, O'Bryan MK. A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse. Plos One. 8: e77311. PMID 24204802 DOI: 10.1371/Journal.Pone.0077311 |
0.316 |
|
| 2013 |
O'Bryan MK, Clark BJ, McLaughlin EA, D'Sylva RJ, O'Donnell L, Wilce JA, Sutherland J, O'Connor AE, Whittle B, Goodnow CC, Ormandy CJ, Jamsai D. RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility. Plos Genetics. 9: e1003628. PMID 23935508 DOI: 10.1371/Journal.Pgen.1003628 |
0.321 |
|
| 2013 |
Crawford G, Enders A, Gileadi U, Stankovic S, Zhang Q, Lambe T, Crockford TL, Lockstone HE, Freeman A, Arkwright PD, Smart JM, Ma CS, Tangye SG, Goodnow CC, Cerundolo V, et al. DOCK8 is critical for the survival and function of NKT cells. Blood. 122: 2052-61. PMID 23929855 DOI: 10.1182/Blood-2013-02-482331 |
0.474 |
|
| 2013 |
Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, et al. Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity. 38: 669-80. PMID 23583642 DOI: 10.1016/J.Immuni.2013.01.011 |
0.432 |
|
| 2013 |
Teh CE, Horikawa K, Arnold CN, Beutler B, Kucharska EM, Vinuesa CG, Bertram EM, Goodnow CC, Enders A. Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation Genes and Immunity. 14: 223-233. PMID 23552399 DOI: 10.1038/Gene.2013.11 |
0.426 |
|
| 2013 |
Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, et al. Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. Plos Genetics. 9: e1003219. PMID 23382690 DOI: 10.1371/Journal.Pgen.1003219 |
0.301 |
|
| 2013 |
Daley SR, Hu DY, Goodnow CC. Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB Journal of Experimental Medicine. 210: 269-285. PMID 23337809 DOI: 10.1084/Jem.20121458 |
0.392 |
|
| 2013 |
Andrews TD, Sjollema G, Goodnow CC. Understanding the immunological impact of the human mutation explosion Trends in Immunology. 34: 99-106. PMID 23333204 DOI: 10.1016/J.It.2012.12.001 |
0.311 |
|
| 2013 |
Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull KR, Jeelall Y, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, Mackay F, ... ... Goodnow CC, et al. B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPl2A Journal of Experimental Medicine. 210: 31-40. PMID 23267016 DOI: 10.1084/Jem.20121076 |
0.486 |
|
| 2013 |
Daley SR, Coakley KM, Hu DY, Randall KL, Jenne CN, Limnander A, Myers DR, Polakos NK, Enders A, Roots C, Balakishnan B, Miosge LA, Sjollema G, Bertram EM, Field MA, ... ... Goodnow CC, et al. Author response: Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies Elife. DOI: 10.7554/Elife.01020.023 |
0.42 |
|
| 2012 |
Enders A, Stankovic S, Teh C, Uldrich AP, Yabas M, Juelich T, Altin JA, Frankenreiter S, Bergmann H, Roots CM, Kyparissoudis K, Goodnow CC, Godfrey DI. ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells Journal of Immunology. 189: 5240-5249. PMID 23105140 DOI: 10.4049/Jimmunol.1201486 |
0.424 |
|
| 2012 |
Jeelall YS, Wang JQ, Law HD, Domaschenz H, Fung HKH, Kallies A, Nutt SL, Goodnow CC, Horikawa K. Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production Journal of Experimental Medicine. 209: 1907-1917. PMID 23027925 DOI: 10.1084/Jem.20112744 |
0.506 |
|
| 2012 |
Andrews TD, Whittle B, Field MA, Balakishnan B, Zhang Y, Shao Y, Cho V, Kirk M, Singh M, Xia Y, Hager J, Winslade S, Sjollema G, Beutler B, Enders A, ... Goodnow CC, et al. Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: An immediate source for thousands of new mouse models Open Biology. 2. PMID 22724066 DOI: 10.1098/Rsob.120061 |
0.309 |
|
| 2012 |
Altin JA, Goodnow CC, Cook MC. IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 188: 5478-88. PMID 22547705 DOI: 10.4049/Jimmunol.1102994 |
0.321 |
|
| 2012 |
Enders A, Bergmann H, Yabas M, Andrews TD, Whittle B, Field M, Balakishnan B, Sontani Y, Miosge L, Sjollema G, Read S, Bertram E, Goodnow CC. Finding new immune regulatory genes by ENU mutagenesis Journal of Translational Medicine. 10. DOI: 10.1186/1479-5876-10-S3-I6 |
0.391 |
|
| 2011 |
Yabas M, Godfrey DI, Goodnow CC, Hoyne GF. Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells Plos One. 6. PMID 22073166 DOI: 10.1371/Journal.Pone.0026440 |
0.463 |
|
| 2011 |
Randall KL, Chan SS, Ma CS, Fung I, Mei Y, Yabas M, Tan A, Arkwright PD, Al Suwairi W, Lugo Reyes SO, Yamazaki-Nakashimada MA, Garcia-Cruz Mde L, Smart JM, Picard C, Okada S, ... ... Goodnow CC, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. The Journal of Experimental Medicine. 208: 2305-20. PMID 22006977 DOI: 10.1084/Jem.20110345 |
0.436 |
|
| 2011 |
Sontani Y, Chapman G, Papathanasiou P, Dunwoodie S, Goodnow CC, Hoyne GF. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL Leukemia Research. 35: 1512-1519. PMID 21840596 DOI: 10.1016/J.Leukres.2011.07.024 |
0.393 |
|
| 2011 |
Silva DG, Daley SR, Hogan J, Lee SK, Teh CE, Hu DY, Lam KP, Goodnow CC, Vinuesa CG. Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells Diabetes. 60: 2102-2111. PMID 21788582 DOI: 10.2337/Db10-1344 |
0.38 |
|
| 2011 |
Tian L, Altin JA, Makaroff LE, Franckaert D, Cook MC, Goodnow CC, Dooley J, Liston A. Foxp3⺠regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis. Blood. 118: 1845-53. PMID 21715314 DOI: 10.1182/Blood-2011-04-346056 |
0.428 |
|
| 2011 |
Hubert FX, Kinkel SA, Davey GM, Phipson B, Mueller SN, Liston A, Proietto AI, Cannon PZF, Forehan S, Smyth GK, Wu L, Goodnow CC, Carbone FR, Scott HS, Heath WR. Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance Blood. 118: 2462-2472. PMID 21505196 DOI: 10.1182/Blood-2010-06-286393 |
0.436 |
|
| 2011 |
Yabas M, Teh CE, Frankenreiter S, Lal D, Roots CM, Whittle B, Andrews DT, Zhang Y, Teoh NC, Sprent J, Tze LE, Kucharska EM, Kofler J, Farell GC, Bröer S, ... Goodnow CC, et al. ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nature Immunology. 12: 441-9. PMID 21423173 DOI: 10.1038/Ni.2011 |
0.481 |
|
| 2011 |
Altin JA, Tian L, Liston A, Bertram EM, Goodnow CC, Cook MC. Decreased T-cell receptor signaling through CARD11 differentially compromises forkhead box protein 3-positive regulatory versus TH2 effector cells to cause allergy Journal of Allergy and Clinical Immunology. 127: 1277-1285. PMID 21320717 DOI: 10.1016/J.Jaci.2010.12.1081 |
0.411 |
|
| 2011 |
Hoyne GF, Flening E, Yabas M, Teh C, Altin JA, Randall K, Thien CBF, Langdon WY, Goodnow CC. Visualizing the role of Cbl-b in control of islet-reactive CD4 T cells and susceptibility to type 1 diabetes Journal of Immunology. 186: 2024-2032. PMID 21248249 DOI: 10.4049/Jimmunol.1002296 |
0.482 |
|
| 2011 |
Tze LE, Horikawa K, Domaschenz H, Howard DR, Roots CM, Rigby RJ, Way DA, Ohmura-Hoshino M, Ishido S, Andoniou CE, Degli-Esposti MA, Goodnow CC. CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. The Journal of Experimental Medicine. 208: 149-65. PMID 21220452 DOI: 10.1084/Jem.20092203 |
0.315 |
|
| 2010 |
Randall KL, Lambe T, Goodnow CC, Cornall RJ. The essential role of DOCK8 in humoral immunity Disease Markers. 29: 141-150. PMID 21178273 DOI: 10.3233/Dma-2010-0739 |
0.367 |
|
| 2010 |
Vinuesa CG, Linterman MA, Goodnow CC, Randall KL. T cells and follicular dendritic cells in germinal center B-cell formation and selection Immunological Reviews. 237: 72-89. PMID 20727030 DOI: 10.1111/J.1600-065X.2010.00937.X |
0.517 |
|
| 2010 |
Teh CE, Daley SR, Enders A, Goodnow CC. T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency Proceedings of the National Academy of Sciences of the United States of America. 107: 14709-14714. PMID 20668237 DOI: 10.1073/Pnas.1009209107 |
0.478 |
|
| 2010 |
Goodnow CC, Vinuesa CG, Randall KL, MacKay F, Brink R. Control systems and decision making for antibody production Nature Immunology. 11: 681-688. PMID 20644574 DOI: 10.1038/Ni.1900 |
0.469 |
|
| 2010 |
Wu Z, Yates AL, Hoyne GF, Goodnow CC. Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from heterogeneous nuclear ribonucleoprotein L-like mutation Journal of Immunology. 185: 231-238. PMID 20505149 DOI: 10.4049/Jimmunol.0903625 |
0.419 |
|
| 2010 |
Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A. CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development Immunity. 32: 342-354. PMID 20346773 DOI: 10.1016/J.Immuni.2010.03.006 |
0.348 |
|
| 2010 |
Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, Manku H, Vyse TJ, Roncador G, Huttley GA, Goodnow CC, Vinuesa CG, Cook MC. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus Arthritis and Rheumatism. 62: 234-244. PMID 20039395 DOI: 10.1002/Art.25032 |
0.403 |
|
| 2010 |
Theodoratos A, Whittle B, Enders A, Tscharke DC, Roots CM, Goodnow CC, Fahrer AM. Mouse strains with point mutations in TAP1 and TAP2 Immunology and Cell Biology. 88: 72-78. PMID 19721454 DOI: 10.1038/Icb.2009.61 |
0.359 |
|
| 2010 |
Randall KL, Lambe T, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, ... ... Goodnow CC, et al. Erratum: Corrigendum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production Nature Immunology. 11: 644-644. DOI: 10.1038/Ni0710-644A |
0.39 |
|
| 2010 |
Randall K, Lambe T, Johnson A, Kucharska E, Vinuesa C, Treanor B, Batista F, Chan T, Camidge T, Brink R, Cornall R, Goodnow C. Immunodeficiency and Abnormal B Cell Synapse Formation due to DOCK8 Mutations in Mice Clinical Immunology. 135: S17. DOI: 10.1016/J.Clim.2010.03.055 |
0.402 |
|
| 2009 |
Randall KL, Lambe T, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, ... ... Goodnow CC, et al. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production Nature Immunology. 10: 1283-1291. PMID 19898472 DOI: 10.1038/Ni.1820 |
0.471 |
|
| 2009 |
Goodnow CC, Crosbie J, Adelstein S, Lavoie TB, Smith-Gill SJ, Brink RA, Pritchard-Briscoe H, Wotherspoon JS, Loblay RH, Raphael K, Trent RJ, Basten A. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5442-8. PMID 19843931 |
0.756 |
|
| 2009 |
Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, Reiner SL, Miller SA, Weinmann AS, Goodnow CC, Lanier LL, et al. T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. The Journal of Experimental Medicine. 206: 2469-81. PMID 19808259 DOI: 10.1084/Jem.20090525 |
0.384 |
|
| 2009 |
Johnson AL, Aravind L, Shulzhenko N, Morgun A, Choi SY, Crockford TL, Lambe T, Domaschenz H, Kucharska EM, Zheng L, Vinuesa CG, Lenardo MJ, Goodnow CC, Cornall RJ, Schwartz RH. Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection Nature Immunology. 10: 831-839. PMID 19597497 DOI: 10.1038/Ni.1769 |
0.413 |
|
| 2009 |
Nijnik A, Dawson S, Crockford TL, Woodbine L, Visetnoi S, Bennett S, Jones M, Turner GD, Jeggo PA, Goodnow CC, Cornall RJ. Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome. The Journal of Clinical Investigation. 119: 1696-705. PMID 19451691 DOI: 10.1172/Jci32743 |
0.366 |
|
| 2009 |
Linterman MA, Rigby RJ, Wong R, Silva D, Withers D, Anderson G, Verma NK, Brink R, Hutloff A, Goodnow CC, Vinuesa CG. Roquin Differentiates the Specialized Functions of Duplicated T Cell Costimulatory Receptor Genes Cd28 and Icos Immunity. 30: 228-241. PMID 19217324 DOI: 10.1016/J.Immuni.2008.12.015 |
0.437 |
|
| 2008 |
Wu Z, Jia X, de la Cruz L, Su XC, Marzolf B, Troisch P, Zak D, Hamilton A, Whittle B, Yu D, Sheahan D, Bertram E, Aderem A, Otting G, Goodnow CC, et al. Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity. 29: 863-75. PMID 19100700 DOI: 10.1016/J.Immuni.2008.11.004 |
0.352 |
|
| 2008 |
Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Xu Y, Jenne CN, Föger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, Cyster JG. The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency. Nature Immunology. 9: 1307-15. PMID 18836449 DOI: 10.1038/Ni.1662 |
0.422 |
|
| 2008 |
Gosling KM, Goodnow CC, Verma NK, Fahrer AM. Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse. Immunology. 125: 208-17. PMID 18397266 DOI: 10.1111/J.1365-2567.2008.02831.X |
0.447 |
|
| 2008 |
Liu M, Duke JL, Richter DJ, Vinuesa CG, Goodnow CC, Kleinstein SH, Schatz DG. Two levels of protection for the B cell genome during somatic hypermutation. Nature. 451: 841-5. PMID 18273020 DOI: 10.1038/Nature06547 |
0.418 |
|
| 2008 |
Yu D, Cook MC, Shin DM, Silva DG, Marshall J, Toellner KM, Havran WL, Caroni P, Cooke MP, Morse HC, MacLennan IC, Goodnow CC, Vinuesa CG. Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunology and Cell Biology. 86: 3-14. PMID 17938642 DOI: 10.1038/Sj.Icb.7100123 |
0.505 |
|
| 2007 |
Yu D, Tan AH, Hu X, Athanasopoulos V, Simpson N, Silva DG, Hutloff A, Giles KM, Leedman PJ, Lam KP, Goodnow CC, Vinuesa CG. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature. 450: 299-303. PMID 18172933 DOI: 10.1038/Nature06253 |
0.431 |
|
| 2007 |
Siggs OM, Miosge LA, Yates AL, Kucharska EM, Sheahan D, Brdicka T, Weiss A, Liston A, Goodnow CC. Opposing Functions of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions Immunity. 27: 912-926. PMID 18093540 DOI: 10.1016/J.Immuni.2007.11.013 |
0.413 |
|
| 2007 |
Gosling KM, Makaroff LE, Theodoratos A, Kim YH, Whittle B, Rui L, Wu H, Hong NA, Kennedy GC, Fritz JA, Yates AL, Goodnow CC, Fahrer AM. A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. Proceedings of the National Academy of Sciences of the United States of America. 104: 12445-50. PMID 17640884 DOI: 10.1073/Pnas.0704870104 |
0.437 |
|
| 2007 |
Goodnow CC. Multistep Pathogenesis of Autoimmune Disease Cell. 130: 25-35. PMID 17632054 DOI: 10.1016/J.Cell.2007.06.033 |
0.41 |
|
| 2007 |
Horikawa K, Martin SW, Pogue SL, Silver K, Peng K, Takatsu K, Goodnow CC. Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors Journal of Experimental Medicine. 204: 759-769. PMID 17420266 DOI: 10.1084/Jem.20061923 |
0.485 |
|
| 2007 |
Liston A, Siggs OM, Goodnow CC. Tracing the action of IL-2 in tolerance to islet-specific antigen Immunology and Cell Biology. 85: 338-342. PMID 17372610 DOI: 10.1038/Sj.Icb.7100049 |
0.37 |
|
| 2007 |
Goodnow CC, Campbell JA, Rui L, Vinuesa CG. Tolerance mechanisms in the late phase of the antibody response. Advances in Experimental Medicine and Biology. 596: 163-8. PMID 17338185 DOI: 10.1007/0-387-46530-8_15 |
0.473 |
|
| 2007 |
Liston A, Hardy K, Pittelkow Y, Wilson SR, Makaroff LE, Fahrer AM, Goodnow CC. Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: Genomic analysis by mRNA profiling Genome Biology. 8. PMID 17239257 DOI: 10.1186/Gb-2007-8-1-R12 |
0.399 |
|
| 2007 |
Li G, Vega R, Nelms K, Gekakis N, Goodnow C, McNamara P, Wu H, Hong NA, Glynne R. A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence. Plos Genetics. 3: e8. PMID 17206865 DOI: 10.1371/Journal.Pgen.0030008 |
0.323 |
|
| 2007 |
Wu Z, Goodnow C, Hoyne G. 166 T Cell Deficiency Resulting form Aberrant Pre-mRNA Alternative Splicing Cytokine. 39: 46. DOI: 10.1016/J.Cyto.2007.07.171 |
0.361 |
|
| 2006 |
Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, et al. Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proceedings of the National Academy of Sciences of the United States of America. 103: 16442-7. PMID 17062753 DOI: 10.1073/Pnas.0607872103 |
0.334 |
|
| 2006 |
Rui L, Healy JI, Blasioli J, Goodnow CC. ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 177: 5337-46. PMID 17015719 DOI: 10.4049/Jimmunol.177.8.5337 |
0.423 |
|
| 2006 |
Manderson AP, Quah B, Botto M, Goodnow CC, Walport MJ, Parish CR. A novel mechanism for complement activation at the surface of B cells following antigen binding. Journal of Immunology (Baltimore, Md. : 1950). 177: 5155-62. PMID 17015700 DOI: 10.4049/Jimmunol.177.8.5155 |
0.434 |
|
| 2006 |
Gray DH, Seach N, Ueno T, Milton MK, Liston A, Lew AM, Goodnow CC, Boyd RL. Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood. 108: 3777-85. PMID 16896157 DOI: 10.1182/Blood-2006-02-004531 |
0.43 |
|
| 2006 |
Cook MC, Vinuesa CG, Goodnow CC. ENU-mutagenesis: insight into immune function and pathology. Current Opinion in Immunology. 18: 627-33. PMID 16889948 DOI: 10.1016/J.Coi.2006.07.011 |
0.331 |
|
| 2006 |
Bléry M, Tze L, Miosge LA, Jun JE, Goodnow CC. Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy. The Journal of Experimental Medicine. 203: 1773-83. PMID 16801401 DOI: 10.1084/Jem.20060552 |
0.419 |
|
| 2006 |
Goodnow CC. Immunology. Discriminating microbe from self suffers a double toll. Science (New York, N.Y.). 312: 1606-8. PMID 16778043 DOI: 10.1126/Science.1129797 |
0.405 |
|
| 2006 |
Nijnik A, Ferry H, Lewis G, Rapsomaniki E, Leung JC, Daser A, Lambe T, Goodnow CC, Cornall RJ. Spontaneous B cell hyperactivity in autoimmune-prone MRL mice. International Immunology. 18: 1127-37. PMID 16735376 DOI: 10.1093/Intimm/Dxl047 |
0.515 |
|
| 2006 |
Rui L, Goodnow CC. Lymphoma and the control of B cell growth and differentiation. Current Molecular Medicine. 6: 291-308. PMID 16712476 DOI: 10.2174/156652406776894563 |
0.467 |
|
| 2006 |
Hoyne GF, Goodnow CC. The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity. Immunological Reviews. 210: 27-39. PMID 16623762 DOI: 10.1111/J.0105-2896.2006.00363.X |
0.406 |
|
| 2005 |
Kennedy CL, O'Connor AE, Sanchez-Partida LG, Holland MK, Goodnow CC, de Kretser DM, O'Bryan MK. A repository of ENU mutant mouse lines and their potential for male fertility research. Molecular Human Reproduction. 11: 871-80. PMID 16421219 DOI: 10.1093/Molehr/Gah251 |
0.307 |
|
| 2005 |
Ferry H, Crockford TL, Cockford TL, Silver K, Rust N, Goodnow CC, Cornall RJ. Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival. European Journal of Immunology. 35: 3655-63. PMID 16278813 DOI: 10.1002/Eji.200535247 |
0.46 |
|
| 2005 |
Papathanasiou P, Goodnow CC. Connecting mammalian genome with phenome by ENU mouse mutagenesis: gene combinations specifying the immune system. Annual Review of Genetics. 39: 241-62. PMID 16053407 DOI: 10.1146/Annurev.Genet.39.110304.095817 |
0.319 |
|
| 2005 |
Miosge LA, Goodnow CC. Genes, pathways and checkpoints in lymphocyte development and homeostasis. Immunology and Cell Biology. 83: 318-35. PMID 16033527 DOI: 10.1111/J.1440-1711.2005.01353.X |
0.443 |
|
| 2005 |
Liston A, Goodnow CC. Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity. Novartis Foundation Symposium. 267: 180-92; discussion 1. PMID 15999807 DOI: 10.1002/047002139X.Ch12 |
0.401 |
|
| 2005 |
Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature. 435: 590-7. PMID 15931211 DOI: 10.1038/Nature03724 |
0.357 |
|
| 2005 |
Vinuesa CG, Cook MC, Angelucci C, Athanasopoulos V, Rui L, Hill KM, Yu D, Domaschenz H, Whittle B, Lambe T, Roberts IS, Copley RR, Bell JI, Cornall RJ, Goodnow CC. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature. 435: 452-8. PMID 15917799 DOI: 10.1038/Nature03555 |
0.437 |
|
| 2005 |
Liston A, Lesage S, Gray DH, Boyd RL, Goodnow CC. Genetic lesions in T-cell tolerance and thresholds for autoimmunity. Immunological Reviews. 204: 87-101. PMID 15790352 DOI: 10.1111/J.0105-2896.2005.00253.X |
0.378 |
|
| 2005 |
Goodnow CC. Safe havens for self-reactive cells. Current Biology : Cb. 2: 417-9. PMID 15335911 DOI: 10.1016/0960-9822(92)90321-Z |
0.385 |
|
| 2005 |
Perkins AC, Papathanasiou P, Goodnow CC, Keys JR. Specific Activation of Human beta-Globin Gene Expression by the Transcription Factor Ikaros. Blood. 106: 3641-3641. DOI: 10.1182/Blood.V106.11.3641.3641 |
0.357 |
|
| 2005 |
Ferry H, Crockford TL, Silver K, Rust N, Goodnow CC, Cornall RJ. Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247) European Journal of Immunology. 35: 3714-3714. DOI: 10.1002/Eji.255590598 |
0.427 |
|
| 2004 |
Liston A, Lesage S, Gray DH, O'Reilly LA, Strasser A, Fahrer AM, Boyd RL, Wilson J, Baxter AG, Gallo EM, Crabtree GR, Peng K, Wilson SR, Goodnow CC. Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity. 21: 817-30. PMID 15589170 DOI: 10.1016/J.Immuni.2004.10.014 |
0.366 |
|
| 2004 |
Liston A, Gray DH, Lesage S, Fletcher AL, Wilson J, Webster KE, Scott HS, Boyd RL, Peltonen L, Goodnow CC. Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. The Journal of Experimental Medicine. 200: 1015-26. PMID 15492124 DOI: 10.1084/Jem.20040581 |
0.4 |
|
| 2004 |
Vinuesa CG, Goodnow CC. Illuminating autoimmune regulators through controlled variation of the mouse genome sequence. Immunity. 20: 669-79. PMID 15189733 DOI: 10.1016/J.Immuni.2004.05.012 |
0.337 |
|
| 2004 |
Kennedy CL, O’Connor AE, Sanchez-Partida LG, Goodnow CC, Kretser DMD, O'Bryan MK. 126. A repository of ENU mutant mouse lines and their potential for male fertility research Reproduction, Fertility and Development. 16: 126-126. DOI: 10.1071/Srb04Abs126 |
0.321 |
|
| 2003 |
Jun JE, Goodnow CC. Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. Nature Immunology. 4: 1057-64. PMID 14586424 DOI: 10.1038/Ni1001 |
0.368 |
|
| 2003 |
Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF, Nelms KA, Smale ST, Goodnow CC. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity. 19: 131-44. PMID 12871645 DOI: 10.1016/S1074-7613(03)00168-7 |
0.331 |
|
| 2003 |
Jun JE, Wilson LE, Vinuesa CG, Lesage S, Blery M, Miosge LA, Cook MC, Kucharska EM, Hara H, Penninger JM, Domashenz H, Hong NA, Glynne RJ, Nelms KA, Goodnow CC. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity. 18: 751-62. PMID 12818157 DOI: 10.1016/S1074-7613(03)00141-9 |
0.466 |
|
| 2003 |
Rui L, Vinuesa CG, Blasioli J, Goodnow CC. Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling. Nature Immunology. 4: 594-600. PMID 12740574 DOI: 10.1038/Ni924 |
0.425 |
|
| 2003 |
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nature Immunology. 4: 350-4. PMID 12612579 DOI: 10.1038/Ni906 |
0.419 |
|
| 2002 |
Vinuesa CG, Cook MC, Cooke MP, Maclennan IC, Goodnow CC. Analysis of B cell memory formation using DNA microarrays. Annals of the New York Academy of Sciences. 975: 33-45. PMID 12538152 DOI: 10.1111/J.1749-6632.2002.Tb05939.X |
0.505 |
|
| 2002 |
Lesage S, Hartley SB, Akkaraju S, Wilson J, Townsend M, Goodnow CC. Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes. The Journal of Experimental Medicine. 196: 1175-88. PMID 12417628 DOI: 10.1084/Jem.20020735 |
0.465 |
|
| 2002 |
Miosge LA, Blasioli J, Blery M, Goodnow CC. Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor κB2 in regulating circulating B cell numbers Journal of Experimental Medicine. 196: 1113-1119. PMID 12391023 DOI: 10.1084/Jem.20020959 |
0.456 |
|
| 2002 |
Prasad SJ, Goodnow CC. Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo International Immunology. 14: 677-684. PMID 12039919 DOI: 10.1093/Intimm/Dxf034 |
0.387 |
|
| 2002 |
Vinuesa CG, Goodnow CC. DNA drives autoimmunity Nature. 416: 595-598. PMID 11948338 DOI: 10.1038/416595A |
0.308 |
|
| 2002 |
Prasad SJ, Goodnow CC. Intrinsic in vitro abnormalities in dendritic cell generation caused by non-MHC non-obese diabetic genes Immunology and Cell Biology. 80: 198-206. PMID 11940121 DOI: 10.1046/J.1440-1711.2002.01074.X |
0.379 |
|
| 2002 |
Loy AL, Goodnow CC. Novel approaches for identifying genes regulating lymphocyte development and function Current Opinion in Immunology. 14: 260-265. PMID 11869902 DOI: 10.1016/S0952-7915(02)00331-X |
0.353 |
|
| 2002 |
Martin SW, Goodnow CC. Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory Nature Immunology. 3: 182-188. PMID 11812996 DOI: 10.1038/Ni752 |
0.454 |
|
| 2001 |
Goodnow CC, Glynne R, Akkaraju S, Rayner J, Mack D, Healy JI, Chaudhry S, Miosge L, Wilson L, Papathanasiou P, Loy A. Autoimmunity, self-tolerance and immune homeostasis: From whole animal phenotypes to molecular pathways Advances in Experimental Medicine and Biology. 490: 33-40. PMID 11505972 DOI: 10.1007/978-1-4615-1243-1_4 |
0.347 |
|
| 2001 |
Goodnow CC. Pathways for self-tolerance and the treatment of autoimmune diseases Lancet. 357: 2115-2121. PMID 11445125 DOI: 10.1016/S0140-6736(00)05185-0 |
0.378 |
|
| 2001 |
Fahrer AM, Bazan JF, Papathanasiou P, Nelms KA, Goodnow CC. A genomic view of immunology Nature. 409: 836-838. PMID 11237003 DOI: 10.1038/35057020 |
0.331 |
|
| 2001 |
Townsend SE, Goodnow CC, Cornall RJ. Single epitope multiple staining to detect ultralow frequency B cells Journal of Immunological Methods. 249: 137-146. PMID 11226471 DOI: 10.1016/S0022-1759(00)00352-5 |
0.43 |
|
| 2000 |
Glynne R, Ghandour G, Rayner J, Mack DH, Goodnow CC. B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays Immunological Reviews. 176: 216-246. PMID 11043780 |
0.375 |
|
| 2000 |
Weintraub BC, Jun JE, Bishop AC, Shokat KM, Thomas ML, Goodnow CC. Entry of B cell receptor into signaling domains is inhibited in tolerant B cells. The Journal of Experimental Medicine. 191: 1443-8. PMID 10770810 DOI: 10.1084/Jem.191.8.1443 |
0.756 |
|
| 2000 |
Pogue SL, Goodnow CC. Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)G1 or IgM/IgG1 tail antigen receptors Journal of Experimental Medicine. 191: 1031-1043. PMID 10727464 DOI: 10.1084/Jem.191.6.1031 |
0.496 |
|
| 2000 |
Glynne RJ, Ghandour G, Goodnow CC. Genomic-scale gene expression analysis of lymphocyte growth, tolerance and malignancy Current Opinion in Immunology. 12: 210-214. PMID 10712948 DOI: 10.1016/S0952-7915(99)00076-X |
0.345 |
|
| 2000 |
Glynne R, Akkaraju S, Healy JI, Rayner J, Goodnow CC, Mack DH. How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis Nature. 403: 672-676. PMID 10688206 DOI: 10.1038/35001102 |
0.458 |
|
| 2000 |
Cornall RJ, Cheng AM, Pawson T, Goodnow CC. Role of Syk in B-cell development and antigen-receptor signaling Proceedings of the National Academy of Sciences of the United States of America. 97: 1713-1718. PMID 10677523 DOI: 10.1073/Pnas.97.4.1713 |
0.512 |
|
| 2000 |
Martin S, Goodnow C. Memory needs no reminders Nature. 407: 576-577. DOI: 10.1038/35036673 |
0.333 |
|
| 1999 |
Goodnow CC, Glynne R, Mack D, Weintraub B, Rathmell J, Healy JI, Chaudhry S, Miosge L, Loy A, Wilson L. Mechanisms of self-tolerance and autoimmunity: from whole-animal phenotypes to molecular pathways. Cold Spring Harbor Symposia On Quantitative Biology. 64: 313-22. PMID 11232301 DOI: 10.1101/Sqb.1999.64.313 |
0.321 |
|
| 1999 |
Cornall RJ, Goodnow CC, Cyster JG. Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway Current Topics in Microbiology and Immunology. 244: 57-68. PMID 10453649 DOI: 10.1007/978-3-642-58537-1_5 |
0.357 |
|
| 1999 |
Townsend SE, Weintraub BC, Goodnow CC. Growing up on the streets: why B-cell development differs from T-cell development. Immunology Today. 20: 217-20. PMID 10322300 DOI: 10.1016/S0167-5699(98)01440-6 |
0.485 |
|
| 1998 |
Prodeus AP, Goerg S, Shen LM, Pozdnyakova OO, Chu L, Alicot EM, Goodnow CC, Carroll MC. A critical role for complement in maintenance of self-tolerance Immunity. 9: 721-731. PMID 9846493 DOI: 10.1016/S1074-7613(00)80669-X |
0.423 |
|
| 1998 |
Rathmell JC, Goodnow CC. The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment Immunology and Cell Biology. 76: 387-394. PMID 9797457 DOI: 10.1046/J.1440-1711.1998.00774.X |
0.486 |
|
| 1998 |
Ying H, Healy JI, Goodnow CC, Parnes JR. Regulation of mouse CD72 gene expression during B lymphocyte development Journal of Immunology. 161: 4760-4767. PMID 9794407 |
0.323 |
|
| 1998 |
Healy JI, Dolmetsch RE, Lewis RS, Goodnow CC. Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes. Novartis Foundation Symposium. 215: 137-44; discussion 1. PMID 9760576 DOI: 10.1002/9780470515525.Ch10 |
0.45 |
|
| 1998 |
Cornall RJ, Goodnow CC. B cell antigen receptor signalling in the balance of tolerance and immunity Novartis Foundation Symposium. 215: 21-30; discussion 30. PMID 9760569 DOI: 10.1002/9780470515525.Ch3 |
0.468 |
|
| 1998 |
Weintraub BC, Goodnow CC. Immune Responses: costimulatory receptors have their say. Current Biology : Cb. 8: R575-7. PMID 9707395 DOI: 10.1016/S0960-9822(07)00365-X |
0.359 |
|
| 1998 |
Rathmell JC, Fournier S, Weintraub BC, Allison JP, Goodnow CC. Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. The Journal of Experimental Medicine. 188: 651-9. PMID 9705947 DOI: 10.1084/Jem.188.4.651 |
0.544 |
|
| 1998 |
Fang W, Weintraub BC, Dunlap B, Garside P, Pape KA, Jenkins MK, Goodnow CC, Mueller DL, Behrens TW. Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. Immunity. 9: 35-45. PMID 9697834 DOI: 10.1016/S1074-7613(00)80586-5 |
0.518 |
|
| 1998 |
Healy JI, Goodnow CC. Positive versus negative signaling by lymphocyte antigen receptors Annual Review of Immunology. 16: 645-670. PMID 9597145 DOI: 10.1146/Annurev.Immunol.16.1.645 |
0.427 |
|
| 1998 |
Cornall RJ, Cyster JG, Hibbs ML, Dunn AR, Otipoby KL, Clark EA, Goodnow CC. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity. 8: 497-508. PMID 9586639 DOI: 10.1016/S1074-7613(00)80554-3 |
0.428 |
|
| 1998 |
Townsend SE, Goodnow CC. Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo Journal of Experimental Medicine. 187: 1611-1621. PMID 9584139 DOI: 10.1084/Jem.187.10.1611 |
0.515 |
|
| 1998 |
Fischer MB, Goerg S, Shen L, Prodeus AP, Goodnow CC, Kelsoe G, Carroll MC. Dependence of germinal center B cells on expression of CD21/CD35 for survival Science. 280: 582-585. PMID 9554848 DOI: 10.1126/Science.280.5363.582 |
0.461 |
|
| 1998 |
Schmidt KN, Hsu CW, Griffin CT, Goodnow CC, Cyster JG. Spontaneous follicular exclusion of SHP1-deficient B cells is conditional on the presence of competitor wild-type B cells. The Journal of Experimental Medicine. 187: 929-37. PMID 9500795 DOI: 10.1084/Jem.187.6.929 |
0.508 |
|
| 1998 |
Prodeus AP, Goerg S, Shen L, Pozdnyakova OO, Alicot EM, Goodnow CC, Carroll MC. A critical role of complement in regulation of self-reactive B cells Molecular Immunology. 35: 338. DOI: 10.1016/S0161-5890(98)90561-2 |
0.448 |
|
| 1997 |
Akkaraju S, Canaan K, Goodnow CC. Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells Journal of Experimental Medicine. 186: 2005-2012. PMID 9396769 DOI: 10.1084/Jem.186.12.2005 |
0.49 |
|
| 1997 |
Inaoki M, Sato S, Weintraub BC, Goodnow CC, Tedder TF. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. The Journal of Experimental Medicine. 186: 1923-31. PMID 9382890 DOI: 10.1084/Jem.186.11.1923 |
0.433 |
|
| 1997 |
Akkaraju S, Ho WY, Leong D, Canaan K, Davis MM, Goodnow CC. A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. Immunity. 7: 255-71. PMID 9285410 DOI: 10.1016/S1074-7613(00)80528-2 |
0.463 |
|
| 1997 |
Goodnow CC. Balancing immunity, autoimmunity, and self-tolerance Annals of the New York Academy of Sciences. 815: 55-66. PMID 9186639 DOI: 10.1111/J.1749-6632.1997.Tb52044.X |
0.335 |
|
| 1997 |
Goodnow CC, Cyster JG. Lymphocyte homing: The scent of a follicle Current Biology. 7. PMID 9162495 DOI: 10.1016/S0960-9822(06)00105-9 |
0.343 |
|
| 1997 |
Healy JI, Dolmetsch RE, Timmerman LA, Cyster JG, Thomas ML, Crabtree GR, Lewis RS, Goodnow CC. Different nuclear signals are activated by the B cell receptor during positive versus negative signaling. Immunity. 6: 419-28. PMID 9133421 DOI: 10.1016/S1074-7613(00)80285-X |
0.475 |
|
| 1997 |
Goodnow CC. Glimpses into the balance between immunity and self-tolerance Ciba Foundation Symposia. 190-207. PMID 9107422 |
0.318 |
|
| 1997 |
Fournier S, Rathmell JC, Goodnow CC, Allison JP. T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 6: 327-39. PMID 9075933 DOI: 10.1016/S1074-7613(00)80335-0 |
0.514 |
|
| 1996 |
Rathmell JC, Townsend SE, Xu JC, Flavell RA, Goodnow CC. Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell. 87: 319-29. PMID 8861915 DOI: 10.1016/S0092-8674(00)81349-5 |
0.535 |
|
| 1996 |
Janeway CA, Goodnow CC, Medzhitov R. Danger - pathogen on the premises! Immunological tolerance. Current Biology : Cb. 6: 519-22. PMID 8805259 DOI: 10.1016/S0960-9822(02)00531-6 |
0.356 |
|
| 1996 |
Cyster JG, Healy JI, Kishihara K, Mak TW, Thomas ML, Goodnow CC. Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45 Nature. 381: 325-328. PMID 8692271 DOI: 10.1038/381325A0 |
0.511 |
|
| 1996 |
Cornall RJ, Goodnow CC, Cyster JG. The regulation of self-reactive B cells. Current Opinion in Immunology. 7: 804-11. PMID 8679124 DOI: 10.1016/0952-7915(95)80052-2 |
0.53 |
|
| 1996 |
Goodnow CC. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proceedings of the National Academy of Sciences of the United States of America. 93: 2264-71. PMID 8637861 DOI: 10.1073/Pnas.93.6.2264 |
0.44 |
|
| 1996 |
Liblau RS, Tisch R, Shokat K, Yang XD, Dumont N, Goodnow CC, Mcdevitt HO. Intravenous injection of soluble antigen induces thymic and peripheral T-cell apoptosis Proceedings of the National Academy of Sciences of the United States of America. 93: 3031-3036. PMID 8610163 DOI: 10.1073/Pnas.93.7.3031 |
0.578 |
|
| 1996 |
Rathmell JC, Goodnow CC. Autoimmunity. The Fas track. Current Biology : Cb. 5: 1218-21. PMID 8574572 DOI: 10.1016/S0960-9822(95)00241-7 |
0.336 |
|
| 1996 |
Dempsey PW, Allison MED, Akkaraju S, Goodnow CC, Fearon DT. C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity Science. 271: 348-350. PMID 8553069 DOI: 10.1126/Science.271.5247.348 |
0.348 |
|
| 1995 |
Cyster JG, Goodnow CC. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate Immunity. 3: 691-701. PMID 8777715 DOI: 10.1016/1074-7613(95)90059-4 |
0.535 |
|
| 1995 |
Hartley SB, Goodnow CC. Censoring of self-reactive B cells with a range of receptor affinities in transgenic mice expressing heavy chains for a lysozyme-specific antibody. International Immunology. 6: 1417-25. PMID 7819151 DOI: 10.1093/Intimm/6.9.1417 |
0.513 |
|
| 1995 |
Lund FE, Solvason NW, Cooke MP, Health AW, Grimaldi JC, Parkhouse RM, Goodnow CC, Howard MC. Signaling through murine CD38 is impaired in antigen receptor-unresponsive B cells. European Journal of Immunology. 25: 1338-45. PMID 7774637 DOI: 10.1002/Eji.1830250531 |
0.456 |
|
| 1995 |
Shokat KM, Goodnow CC. Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature. 375: 334-8. PMID 7753200 DOI: 10.1038/375334A0 |
0.642 |
|
| 1995 |
Brink R, Fulcher DA, Goodnow CC, Basten A. Differential regulation of early and late stages of B lymphocyte development by the mu and delta membrane heavy chains of Ig. International Immunology. 6: 1905-16. PMID 7696208 DOI: 10.1093/Intimm/6.12.1905 |
0.69 |
|
| 1995 |
Cyster JG, Goodnow CC. Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords Journal of Experimental Medicine. 182: 581-586. PMID 7629515 DOI: 10.1084/Jem.182.2.581 |
0.444 |
|
| 1995 |
Rathmell JC, Cooke MP, Ho WY, Grein J, Townsend SE, Davis MM, Goodnow CC. CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature. 376: 181-4. PMID 7603571 DOI: 10.1038/376181A0 |
0.507 |
|
| 1995 |
Cyster JG, Goodnow CC. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection Immunity. 2: 13-24. PMID 7600299 DOI: 10.1016/1074-7613(95)90075-6 |
0.511 |
|
| 1995 |
Brink R, Goodnow CC, Basten A. IgD expression on B cells is more efficient than IgM but both receptors are functionally equivalent in up-regulation CD80/CD86 co-stimulatory molecules. European Journal of Immunology. 25: 1980-4. PMID 7542598 DOI: 10.1002/Eji.1830250727 |
0.74 |
|
| 1995 |
Goodnow CC, Cyster JG, Hartley SB, Bell SE, Cooke MP, Healy JI, Akkaraju S, Rathmell JC, Pogue SL, Shokat KP. Self-tolerance checkpoints in B lymphocyte development Advances in Immunology. 59: 279-368. PMID 7484462 DOI: 10.1016/S0065-2776(08)60633-1 |
0.517 |
|
| 1994 |
Cooke MP, Heath AW, Shokat KM, Zeng Y, Finkelman FD, Linsley PS, Howard M, Goodnow CC. Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. The Journal of Experimental Medicine. 179: 425-38. PMID 8294858 DOI: 10.1084/Jem.179.2.425 |
0.668 |
|
| 1994 |
Ho WY, Cooke MP, Goodnow CC, Davis MM. Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells. The Journal of Experimental Medicine. 179: 1539-49. PMID 7909325 DOI: 10.1084/Jem.179.5.1539 |
0.515 |
|
| 1994 |
Cyster JG, Hartley SB, Goodnow CC. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire Nature. 371: 389-395. PMID 7522305 DOI: 10.1038/371389A0 |
0.498 |
|
| 1994 |
Bell S, Goodnow C. A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes. The Embo Journal. 13: 816-826. DOI: 10.1002/J.1460-2075.1994.Tb06324.X |
0.479 |
|
| 1993 |
Hartley SB, Cooke MP, Fulcher DA, Harris AW, Cory S, Basten A, Goodnow CC. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell. 72: 325-35. PMID 8431943 DOI: 10.1016/0092-8674(93)90111-3 |
0.754 |
|
| 1993 |
Nossal GJ, Herold KC, Goodnow CC. Autoimmune tolerance and type 1 (insulin-dependent) diabetes mellitus. Diabetologia. S49-59. PMID 1478378 DOI: 10.1007/Bf00586279 |
0.528 |
|
| 1993 |
Goodnow CC. B-cell tolerance. Current Opinion in Immunology. 4: 703-10. PMID 1281638 DOI: 10.1016/0952-7915(92)90049-K |
0.461 |
|
| 1992 |
Mason DY, Jones M, Goodnow CC. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. International Immunology. 4: 163-75. PMID 1622894 DOI: 10.1093/intimm/4.2.163 |
0.407 |
|
| 1992 |
Goodnow CC. Transgenic mice and analysis of B-cell tolerance. Annual Review of Immunology. 10: 489-518. PMID 1590994 DOI: 10.1146/Annurev.Iy.10.040192.002421 |
0.525 |
|
| 1992 |
Brink R, Goodnow CC, Crosbie J, Adams E, Ens J, Mason DY, Hartley SB, Basten A. Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen Journal of Experimental Medicine. 176: 991-1005. PMID 1402669 DOI: 10.1084/Jem.176.4.991 |
0.773 |
|
| 1991 |
Hartley SB, Crosbie J, Brink R, Kantor AB, Basten A, Goodnow CC. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature. 353: 765-9. PMID 1944535 DOI: 10.1038/353765A0 |
0.751 |
|
| 1991 |
Basten A, Brink R, Peake P, Adams E, Crosbie J, Hartley S, Goodnow CC. Self tolerance in the B-cell repertoire. Immunological Reviews. 122: 5-19. PMID 1937544 DOI: 10.1111/J.1600-065X.1991.Tb00593.X |
0.731 |
|
| 1991 |
Adelstein S, Pritchard-Briscoe H, Anderson TA, Crosbie J, Gammon G, Loblay RH, Basten A, Goodnow CC. Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. Science (New York, N.Y.). 251: 1223-5. PMID 1900950 DOI: 10.1126/Science.1900950 |
0.757 |
|
| 1991 |
Goodnow CC, Brink R, Adams E. Breakdown of self-tolerance in anergic B lymphocytes. Nature. 352: 532-6. PMID 1830923 DOI: 10.1038/352532A0 |
0.475 |
|
| 1991 |
Brooks A, Hartley S, Kjer-Nielsen L, Perera J, Goodnow CC, Basten A, McCluskey J. Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme. Proceedings of the National Academy of Sciences of the United States of America. 88: 3290-4. PMID 1707537 DOI: 10.1073/Pnas.88.8.3290 |
0.696 |
|
| 1990 |
Goodnow CC. Cellular mechanisms of self-tolerance. Current Opinion in Immunology. 2: 226-36. PMID 2696485 DOI: 10.1016/0952-7915(89)90192-1 |
0.304 |
|
| 1990 |
Goodnow CC, Adelstein S, Basten A. The need for central and peripheral tolerance in the B cell repertoire. Science (New York, N.Y.). 248: 1373-9. PMID 2356469 DOI: 10.1126/Science.2356469 |
0.761 |
|
| 1990 |
Arnold B, Goodnow C, Hengartner H, Hämmerling G. The coming of transgenic mice: tolerance and immune reactivity. Immunology Today. 11: 69-72. PMID 2337452 DOI: 10.1016/0167-5699(90)90026-6 |
0.33 |
|
| 1990 |
Adams E, Basten A, Goodnow CC. Intrinsic B-cell hyporesponsiveness accounts for self-tolerance in lysozyme/anti-lysozyme double-transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 87: 5687-91. PMID 2143020 DOI: 10.1073/Pnas.87.15.5687 |
0.767 |
|
| 1989 |
Goodnow CC, Crosbie J, Adelstein S, Lavoie TB, Smith-Gill SJ, Mason DY, Jorgensen H, Brink RA, Pritchard-Briscoe H, Loughnan M. Clonal silencing of self-reactive B lymphocytes in a transgenic mouse model. Cold Spring Harbor Symposia On Quantitative Biology. 54: 907-20. PMID 2701221 DOI: 10.1101/Sqb.1989.054.01.106 |
0.427 |
|
| 1989 |
Goodnow CC, Crosbie J, Jorgensen H, Brink RA, Basten A. Induction of self-tolerance in mature peripheral B lymphocytes. Nature. 342: 385-91. PMID 2586609 DOI: 10.1038/342385A0 |
0.764 |
|
| 1988 |
Berg LJ, Fazekas de St Groth B, Ivars F, Goodnow CC, Gilfillan S, Garchon HJ, Davis MM. Expression of T-cell receptor alpha-chain genes in transgenic mice. Molecular and Cellular Biology. 8: 5459-69. PMID 3266655 DOI: 10.1128/Mcb.8.12.5459 |
0.42 |
|
| 1988 |
Goodnow CC, Crosbie J, Adelstein S, Lavoie TB, Smith-Gill SJ, Brink RA, Pritchard-Briscoe H, Wotherspoon JS, Loblay RH, Raphael K. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature. 334: 676-82. PMID 3261841 DOI: 10.1038/334676A0 |
0.491 |
|
| 1987 |
Davis MM, Gascoigne NR, Lindsten T, Goodnow C, Chien Y. Murine T-cell receptor genes Advances in Experimental Medicine and Biology. 213: 13-17. PMID 3498293 DOI: 10.1007/978-1-4684-5323-2_2 |
0.411 |
|
| 1987 |
Gascoigne NR, Goodnow CC, Dudzik KI, Oi VT, Davis MM. Secretion of a chimeric T-cell receptor-immunoglobulin protein. Proceedings of the National Academy of Sciences of the United States of America. 84: 2936-40. PMID 3472243 DOI: 10.1073/Pnas.84.9.2936 |
0.409 |
|
| 1986 |
Davis MM, Lindsten T, Gascoigne NR, Goodnow C, Chien YH. T-cell receptor gene structure and function. Cellular Immunology. 99: 24-8. PMID 3489561 DOI: 10.1016/0008-8749(86)90211-X |
0.402 |
|
| 1986 |
Gascoigne NR, Waters S, Elliott JF, Victor-Kobrin C, Goodnow C, Davis MM, Bona CA. Expression of T cell receptor genes in an antigen-specific hybridoma and radiation-induced variants. The Journal of Experimental Medicine. 164: 113-30. PMID 2425026 DOI: 10.1084/Jem.164.1.113 |
0.38 |
|
| 1985 |
Walker KZ, Boux HA, Hayden GE, Goodnow CC, Raison RL. A monoclonal antibody with selectivity for human kappa myeloma and lymphoma cells which has potential as a therapeutic agent. Advances in Experimental Medicine and Biology. 186: 833-41. PMID 3931433 DOI: 10.1007/978-1-4613-2463-8_101 |
0.43 |
|
| 1985 |
Becker DM, Pattern P, Chien Y, Yokota T, Eshhar Z, Giedlin M, Gascoigne NR, Goodnow C, Wolf R, Arai K. Variability and repertoire size of T-cell receptor V alpha gene segments. Nature. 317: 430-4. PMID 2995827 DOI: 10.1038/317430A0 |
0.384 |
|
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