Christopher C. Goodnow - Publications

Australian National University, Acton, Australian Capital Territory, Australia 
mechanisms regulating the immune system

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, ... ... Goodnow CC, et al. A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation. Plos Genetics. 13: e1007072. PMID 29117179 DOI: 10.1371/journal.pgen.1007072  0.4
2016 Wu Z, Liang R, Ohnesorg T, Cho V, Lam W, Abhayaratna WP, Gatenby PA, Perera C, Zhang Y, Whittle B, Sinclair A, Goodnow CC, Field M, Andrews TD, Cook MC. Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion. Plos Genetics. 12: e1006067. PMID 27227454 DOI: 10.1371/journal.pgen.1006067  0.44
2016 Hillhouse EE, Liston A, Collin R, Desautels E, Goodnow CC, Lesage S. TCR transgenic mice reveal the impact of type 1 diabetes loci on early and late disease checkpoints. Immunology and Cell Biology. PMID 27046082 DOI: 10.1038/icb.2016.27  0.44
2015 Lim SL, Qu ZP, Kortschak RD, Lawrence DM, Geoghegan J, Hempfling AL, Bergmann M, Goodnow CC, Ormandy CJ, Wong L, Mann J, Scott HS, Jamsai D, Adelson DL, O'Bryan MK. Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse. Plos Genetics. 11: e1005782. PMID 26714033 DOI: 10.1371/journal.pgen.1005782  0.4
2015 Wertz IE, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman RJ, Horikawa K, Dugger D, ... ... Goodnow CC, et al. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature. 528: 370-5. PMID 26649818 DOI: 10.1038/nature16165  0.44
2015 Lim SL, Qu ZP, Kortschak RD, Lawrence DM, Geoghegan J, Hempfling AL, Bergmann M, Goodnow CC, Ormandy CJ, Wong L, Mann J, Scott HS, Jamsai D, Adelson DL, O'Bryan MK. HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse. Plos Genetics. 11: e1005620. PMID 26496356 DOI: 10.1371/journal.pgen.1005620  0.44
2015 Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT, Liu PS, Lill JR, Li H, Wu J, Kummerfeld S, ... ... Goodnow CC, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature. 526: 666-71. PMID 26375259 DOI: 10.1038/nature15541  0.44
2015 Johar AS, Mastronardi C, Rojas-Villarraga A, Patel HR, Chuah A, Peng K, Higgins A, Milburn P, Palmer S, Silva-Lara MF, Velez JI, Andrews D, Field M, Huttley G, Goodnow C, et al. Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome. Journal of Translational Medicine. 13: 173. PMID 26031516 DOI: 10.1186/s12967-015-0525-x  0.44
2015 Liu Y, DeBoer K, de Kretser DM, O'Donnell L, O'Connor AE, Merriner DJ, Okuda H, Whittle B, Jans DA, Efthymiadis A, McLachlan RI, Ormandy CJ, Goodnow CC, Jamsai D, O'Bryan MK. LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility. Plos Genetics. 11: e1005090. PMID 25781171 DOI: 10.1371/journal.pgen.1005090  0.4
2015 Siggs OM, Miosge LA, Daley SR, Asquith K, Foster PS, Liston A, Goodnow CC. Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2587-95. PMID 25662996 DOI: 10.4049/jimmunol.1400326  0.44
2015 Johar AS, Anaya JM, Andrews D, Patel HR, Field M, Goodnow C, Arcos-Burgos M. Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture Autoimmunity Reviews. 14: 204-209. PMID 25447288 DOI: 10.1016/j.autrev.2014.10.021  0.44
2015 Liu Y, DeBoer K, de Kretser DM, O’Donnell L, O’Connor AE, Merriner DJ, Okuda H, Whittle B, Jans DA, Efthymiadis A, McLachlan RI, Ormandy CJ, Goodnow CC, Jamsai D, O’Bryan MK. LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility Plos Genetics. 11. DOI: 10.1371/journal.pgen.1005090  0.44
2015 Fuchs S, Rensing-Ehl A, Pannicke U, Lorenz MR, Fisch P, Jeelall Y, Rohr J, Speckmann C, Vraetz T, Farmand S, Schmitt-Graeff A, Krüger M, Strahm B, Henneke P, Enders A, ... ... Goodnow C, et al. Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency Blood. 126: 1658-1669. DOI: 10.1182/blood-2015-03-631374  0.44
2015 Flesch IEA, Randall KL, Hollett NA, Di Law H, Miosge LA, Sontani Y, Goodnow CC, Tscharke DC. Delayed control of herpes simplex virus infection and impaired CD4+ T-cell migration to the skin in mouse models of DOCK8 deficiency Immunology and Cell Biology. 93: 517-521. DOI: 10.1038/icb.2015.32  0.44
2015 Tangye SG, Brink R, Goodnow CC, Phan TG. SnapShot: Interactions between B Cells and T Cells Cell. 162: 926-926.e1. DOI: 10.1016/j.cell.2015.07.055  0.44
2014 Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, ... Goodnow CC, et al. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. Proceedings of the National Academy of Sciences of the United States of America. 111: E2567-75. PMID 24821781 DOI: 10.1073/pnas.1406974111  0.44
2014 Cho V, Mei Y, Sanny A, Chan S, Enders A, Bertram EM, Tan A, Goodnow CC, Andrews TD. The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA. Genome Biology. 15: R26. PMID 24476532 DOI: 10.1186/gb-2014-15-1-r26  0.44
2014 Bull KR, Mason T, Rimmer AJ, Crockford TL, Silver KL, Bouriez-Jones T, Hough TA, Chaudhry S, Roberts ISD, Goodnow CC, Cornall RJ. Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome Journal of Pathology. 233: 18-26. PMID 24293254 DOI: 10.1002/path.4308  0.44
2014 Siggs OM, Yates AL, Schlenner S, Liston A, Lesage S, Goodnow CC. A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction Immunology. 141: 587-595. PMID 24266404 DOI: 10.1111/imm.12220  0.44
2013 Daley SR, Coakley KM, Hu DY, Randall KL, Jenne CN, Limnander A, Myers DR, Polakos NK, Enders A, Roots C, Balakishnan B, Miosge LA, Sjollema G, Bertram EM, Field MA, ... ... Goodnow CC, et al. Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies. Elife. 2: e01020. PMID 24336796 DOI: 10.7554/eLife.01020  0.44
2013 Jamsai D, Clark BJ, Smith SJ, Whittle B, Goodnow CC, Ormandy CJ, O'Bryan MK. A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse. Plos One. 8: e77311. PMID 24204802 DOI: 10.1371/journal.pone.0077311  0.44
2013 O'Bryan MK, Clark BJ, McLaughlin EA, D'Sylva RJ, O'Donnell L, Wilce JA, Sutherland J, O'Connor AE, Whittle B, Goodnow CC, Ormandy CJ, Jamsai D. RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility. Plos Genetics. 9: e1003628. PMID 23935508 DOI: 10.1371/journal.pgen.1003628  0.44
2013 Crawford G, Enders A, Gileadi U, Stankovic S, Zhang Q, Lambe T, Crockford TL, Lockstone HE, Freeman A, Arkwright PD, Smart JM, Ma CS, Tangye SG, Goodnow CC, Cerundolo V, et al. DOCK8 is critical for the survival and function of NKT cells. Blood. 122: 2052-61. PMID 23929855 DOI: 10.1182/blood-2013-02-482331  0.44
2013 Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, et al. Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity. 38: 669-80. PMID 23583642 DOI: 10.1016/j.immuni.2013.01.011  0.44
2013 Teh CE, Horikawa K, Arnold CN, Beutler B, Kucharska EM, Vinuesa CG, Bertram EM, Goodnow CC, Enders A. Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation Genes and Immunity. 14: 223-233. PMID 23552399 DOI: 10.1038/gene.2013.11  0.44
2013 Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, et al. Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. Plos Genetics. 9: e1003219. PMID 23382690 DOI: 10.1371/journal.pgen.1003219  0.44
2013 Daley SR, Hu DY, Goodnow CC. Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB Journal of Experimental Medicine. 210: 269-285. PMID 23337809 DOI: 10.1084/jem.20121458  0.44
2013 Andrews TD, Sjollema G, Goodnow CC. Understanding the immunological impact of the human mutation explosion Trends in Immunology. 34: 99-106. PMID 23333204 DOI: 10.1016/  0.44
2013 Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull KR, Jeelall Y, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, Mackay F, ... ... Goodnow CC, et al. B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPl2A Journal of Experimental Medicine. 210: 31-40. PMID 23267016 DOI: 10.1084/jem.20121076  0.44
2012 Enders A, Stankovic S, Teh C, Uldrich AP, Yabas M, Juelich T, Altin JA, Frankenreiter S, Bergmann H, Roots CM, Kyparissoudis K, Goodnow CC, Godfrey DI. ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells Journal of Immunology. 189: 5240-5249. PMID 23105140 DOI: 10.4049/jimmunol.1201486  0.44
2012 Lo JC, Jamsai D, O'Connor AE, Borg C, Clark BJ, Whisstock JC, Field MC, Adams V, Ishikawa T, Aitken RJ, Whittle B, Goodnow CC, Ormandy CJ, O'Bryan MK. RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Plos Genetics. 8: e1002969. PMID 23055941 DOI: 10.1371/journal.pgen.1002969  0.44
2012 Jeelall YS, Wang JQ, Law HD, Domaschenz H, Fung HKH, Kallies A, Nutt SL, Goodnow CC, Horikawa K. Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production Journal of Experimental Medicine. 209: 1907-1917. PMID 23027925 DOI: 10.1084/jem.20112744  0.44
2012 Andrews TD, Whittle B, Field MA, Balakishnan B, Zhang Y, Shao Y, Cho V, Kirk M, Singh M, Xia Y, Hager J, Winslade S, Sjollema G, Beutler B, Enders A, ... Goodnow CC, et al. Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: An immediate source for thousands of new mouse models Open Biology. 2. PMID 22724066 DOI: 10.1098/rsob.120061  0.44
2012 O'Donnell L, Rhodes D, Smith SJ, Merriner DJ, Clark BJ, Borg C, Whittle B, O'Connor AE, Smith LB, McNally FJ, de Kretser DM, Goodnow CC, Ormandy CJ, Jamsai D, O'Bryan MK. An essential role for katanin p80 and microtubule severing in male gamete production. Plos Genetics. 8: e1002698. PMID 22654669 DOI: 10.1371/journal.pgen.1002698  0.44
2012 Altin JA, Goodnow CC, Cook MC. IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 188: 5478-88. PMID 22547705 DOI: 10.4049/jimmunol.1102994  0.44
2011 Yabas M, Godfrey DI, Goodnow CC, Hoyne GF. Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells Plos One. 6. PMID 22073166 DOI: 10.1371/journal.pone.0026440  0.44
2011 Randall KL, Chan SS, Ma CS, Fung I, Mei Y, Yabas M, Tan A, Arkwright PD, Al Suwairi W, Lugo Reyes SO, Yamazaki-Nakashimada MA, Garcia-Cruz Mde L, Smart JM, Picard C, Okada S, ... ... Goodnow CC, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. The Journal of Experimental Medicine. 208: 2305-20. PMID 22006977 DOI: 10.1084/jem.20110345  0.44
2011 Sontani Y, Chapman G, Papathanasiou P, Dunwoodie S, Goodnow CC, Hoyne GF. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL Leukemia Research. 35: 1512-1519. PMID 21840596 DOI: 10.1016/j.leukres.2011.07.024  0.44
2011 Silva DG, Daley SR, Hogan J, Lee SK, Teh CE, Hu DY, Lam KP, Goodnow CC, Vinuesa CG. Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells Diabetes. 60: 2102-2111. PMID 21788582 DOI: 10.2337/db10-1344  0.44
2011 Tian L, Altin JA, Makaroff LE, Franckaert D, Cook MC, Goodnow CC, Dooley J, Liston A. Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis. Blood. 118: 1845-53. PMID 21715314 DOI: 10.1182/blood-2011-04-346056  0.44
2011 Hubert FX, Kinkel SA, Davey GM, Phipson B, Mueller SN, Liston A, Proietto AI, Cannon PZF, Forehan S, Smyth GK, Wu L, Goodnow CC, Carbone FR, Scott HS, Heath WR. Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance Blood. 118: 2462-2472. PMID 21505196 DOI: 10.1182/blood-2010-06-286393  0.44
2011 Yabas M, Teh CE, Frankenreiter S, Lal D, Roots CM, Whittle B, Andrews DT, Zhang Y, Teoh NC, Sprent J, Tze LE, Kucharska EM, Kofler J, Farell GC, Bröer S, ... Goodnow CC, et al. ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nature Immunology. 12: 441-9. PMID 21423173 DOI: 10.1038/ni.2011  0.44
2011 Altin JA, Tian L, Liston A, Bertram EM, Goodnow CC, Cook MC. Decreased T-cell receptor signaling through CARD11 differentially compromises forkhead box protein 3-positive regulatory versus TH2 effector cells to cause allergy Journal of Allergy and Clinical Immunology. 127: 1277-1285. PMID 21320717 DOI: 10.1016/j.jaci.2010.12.1081  0.44
2011 Hoyne GF, Flening E, Yabas M, Teh C, Altin JA, Randall K, Thien CBF, Langdon WY, Goodnow CC. Visualizing the role of Cbl-b in control of islet-reactive CD4 T cells and susceptibility to type 1 diabetes Journal of Immunology. 186: 2024-2032. PMID 21248249 DOI: 10.4049/jimmunol.1002296  0.44
2011 Tze LE, Horikawa K, Domaschenz H, Howard DR, Roots CM, Rigby RJ, Way DA, Ohmura-Hoshino M, Ishido S, Andoniou CE, Degli-Esposti MA, Goodnow CC. CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. The Journal of Experimental Medicine. 208: 149-65. PMID 21220452 DOI: 10.1084/jem.20092203  0.44
2011 Beutler B, Goodnow CC. How host defense is encoded in the mammalian genome Mammalian Genome. 22: 1-5. PMID 21184083 DOI: 10.1007/s00335-010-9312-4  0.44
2010 Randall KL, Lambe T, Goodnow CC, Cornall RJ. The essential role of DOCK8 in humoral immunity Disease Markers. 29: 141-150. PMID 21178273 DOI: 10.3233/DMA-2010-0739  0.44
2010 Xia Y, Won S, Du X, Lin P, Ross C, La Vine D, Wiltshire S, Leiva G, Vidal SM, Whittle B, Goodnow CC, Koziol J, Moresco EMY, Beutler B. Bulk segregation mapping of mutations in closely related strains of mice Genetics. 186: 1139-1145. PMID 20923982 DOI: 10.1534/genetics.110.121160  0.44
2010 Vinuesa CG, Linterman MA, Goodnow CC, Randall KL. T cells and follicular dendritic cells in germinal center B-cell formation and selection Immunological Reviews. 237: 72-89. PMID 20727030 DOI: 10.1111/j.1600-065X.2010.00937.x  0.44
2010 Teh CE, Daley SR, Enders A, Goodnow CC. T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency Proceedings of the National Academy of Sciences of the United States of America. 107: 14709-14714. PMID 20668237 DOI: 10.1073/pnas.1009209107  0.44
2010 Goodnow CC, Vinuesa CG, Randall KL, MacKay F, Brink R. Control systems and decision making for antibody production Nature Immunology. 11: 681-688. PMID 20644574 DOI: 10.1038/ni.1900  0.44
2010 Wu Z, Yates AL, Hoyne GF, Goodnow CC. Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from heterogeneous nuclear ribonucleoprotein L-like mutation Journal of Immunology. 185: 231-238. PMID 20505149 DOI: 10.4049/jimmunol.0903625  0.44
2010 Athanasopoulos V, Barker A, Yu D, Tan AH, Srivastava M, Contreras N, Wang J, Lam KP, Brown SH, Goodnow CC, Dixon NE, Leedman PJ, Saint R, Vinuesa CG. The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs. The Febs Journal. 277: 2109-27. PMID 20412057 DOI: 10.1111/j.1742-4658.2010.07628.x  0.44
2010 Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A. CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development Immunity. 32: 342-354. PMID 20346773 DOI: 10.1016/j.immuni.2010.03.006  0.44
2010 Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, Manku H, Vyse TJ, Roncador G, Huttley GA, Goodnow CC, Vinuesa CG, Cook MC. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus Arthritis and Rheumatism. 62: 234-244. PMID 20039395 DOI: 10.1002/art.25032  0.44
2010 Theodoratos A, Whittle B, Enders A, Tscharke DC, Roots CM, Goodnow CC, Fahrer AM. Mouse strains with point mutations in TAP1 and TAP2 Immunology and Cell Biology. 88: 72-78. PMID 19721454 DOI: 10.1038/icb.2009.61  0.44
2009 Randall KL, Lambe T, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, ... ... Goodnow CC, et al. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production Nature Immunology. 10: 1283-1291. PMID 19898472 DOI: 10.1038/ni.1820  0.44
2009 Goodnow CC, Crosbie J, Adelstein S, Lavoie TB, Smith-Gill SJ, Brink RA, Pritchard-Briscoe H, Wotherspoon JS, Loblay RH, Raphael K, Trent RJ, Basten A. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5442-8. PMID 19843931  0.44
2009 Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, Reiner SL, Miller SA, Weinmann AS, Goodnow CC, Lanier LL, et al. T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. The Journal of Experimental Medicine. 206: 2469-81. PMID 19808259 DOI: 10.1084/jem.20090525  0.44
2009 Johnson AL, Aravind L, Shulzhenko N, Morgun A, Choi SY, Crockford TL, Lambe T, Domaschenz H, Kucharska EM, Zheng L, Vinuesa CG, Lenardo MJ, Goodnow CC, Cornall RJ, Schwartz RH. Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection Nature Immunology. 10: 831-839. PMID 19597497 DOI: 10.1038/ni.1769  0.44
2009 Nijnik A, Dawson S, Crockford TL, Woodbine L, Visetnoi S, Bennett S, Jones M, Turner GD, Jeggo PA, Goodnow CC, Cornall RJ. Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome. The Journal of Clinical Investigation. 119: 1696-705. PMID 19451691 DOI: 10.1172/JCI32743  0.44
2009 Linterman MA, Rigby RJ, Wong R, Silva D, Withers D, Anderson G, Verma NK, Brink R, Hutloff A, Goodnow CC, Vinuesa CG. Roquin Differentiates the Specialized Functions of Duplicated T Cell Costimulatory Receptor Genes Cd28 and Icos Immunity. 30: 228-241. PMID 19217324 DOI: 10.1016/j.immuni.2008.12.015  0.44
2009 Chu J, Hong NA, Masuda CA, Jenkins BV, Nelms KA, Goodnow CC, Glynne RJ, Wu H, Masliah E, Joazeiro CA, Kay SA. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 106: 2097-103. PMID 19196968 DOI: 10.1073/pnas.0812819106  0.44
2009 Lambe T, Simpson RJ, Dawson S, Bouriez-Jones T, Crockford TL, Lepherd M, Latunde-Dada GO, Robinson H, Raja KB, Campagna DR, Villarreal G, Ellory JC, Goodnow CC, Fleming MD, McKie AT, et al. Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism Blood. 113: 1805-1808. PMID 18955558 DOI: 10.1182/blood-2007-11-120402  0.44
2008 Wu Z, Jia X, de la Cruz L, Su XC, Marzolf B, Troisch P, Zak D, Hamilton A, Whittle B, Yu D, Sheahan D, Bertram E, Aderem A, Otting G, Goodnow CC, et al. Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity. 29: 863-75. PMID 19100700 DOI: 10.1016/j.immuni.2008.11.004  0.44
2008 Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Xu Y, Jenne CN, Föger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, Cyster JG. The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency. Nature Immunology. 9: 1307-15. PMID 18836449 DOI: 10.1038/ni.1662  0.44
2008 Gosling KM, Goodnow CC, Verma NK, Fahrer AM. Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse. Immunology. 125: 208-17. PMID 18397266 DOI: 10.1111/j.1365-2567.2008.02831.x  0.44
2008 Keys JR, Tallack MR, Zhan Y, Papathanasiou P, Goodnow CC, Gaensler KM, Crossley M, Dekker J, Perkins AC. A mechanism for Ikaros regulation of human globin gene switching British Journal of Haematology. 141: 398-406. PMID 18318763 DOI: 10.1111/j.1365-2141.2008.07065.x  0.44
2008 Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, Thornton DJ, Png CW, Crockford TL, Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, ... Goodnow CC, et al. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. Plos Medicine. 5: e54. PMID 18318598 DOI: 10.1371/journal.pmed.0050054  0.44
2008 Liu M, Duke JL, Richter DJ, Vinuesa CG, Goodnow CC, Kleinstein SH, Schatz DG. Two levels of protection for the B cell genome during somatic hypermutation. Nature. 451: 841-5. PMID 18273020 DOI: 10.1038/nature06547  0.44
2008 Yu D, Cook MC, Shin DM, Silva DG, Marshall J, Toellner KM, Havran WL, Caroni P, Cooke MP, Morse HC, MacLennan IC, Goodnow CC, Vinuesa CG. Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunology and Cell Biology. 86: 3-14. PMID 17938642 DOI: 10.1038/sj.icb.7100123  0.44
2008 Yu D, Tan AHM, Hu X, Athanasopoulos V, Simpson N, Silva DG, Hutloff A, Giles KM, Leedman PJ, Lam KP, Goodnow CC, Vinuesa CG. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA (Nature (2007) 450, (299-303)) Nature. 451: 1022. DOI: 10.1038/nature06729  0.44
2007 Yu D, Tan AH, Hu X, Athanasopoulos V, Simpson N, Silva DG, Hutloff A, Giles KM, Leedman PJ, Lam KP, Goodnow CC, Vinuesa CG. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature. 450: 299-303. PMID 18172933 DOI: 10.1038/nature06253  0.44
2007 Siggs OM, Miosge LA, Yates AL, Kucharska EM, Sheahan D, Brdicka T, Weiss A, Liston A, Goodnow CC. Opposing Functions of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions Immunity. 27: 912-926. PMID 18093540 DOI: 10.1016/j.immuni.2007.11.013  0.44
2007 Gosling KM, Makaroff LE, Theodoratos A, Kim YH, Whittle B, Rui L, Wu H, Hong NA, Kennedy GC, Fritz JA, Yates AL, Goodnow CC, Fahrer AM. A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. Proceedings of the National Academy of Sciences of the United States of America. 104: 12445-50. PMID 17640884 DOI: 10.1073/pnas.0704870104  0.44
2007 Goodnow CC. Multistep Pathogenesis of Autoimmune Disease Cell. 130: 25-35. PMID 17632054 DOI: 10.1016/j.cell.2007.06.033  0.44
2007 Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, et al. DNA repair is limiting for haematopoietic stem cells during ageing. Nature. 447: 686-90. PMID 17554302 DOI: 10.1038/nature05875  0.44
2007 Horikawa K, Martin SW, Pogue SL, Silver K, Peng K, Takatsu K, Goodnow CC. Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors Journal of Experimental Medicine. 204: 759-769. PMID 17420266 DOI: 10.1084/jem.20061923  0.44
2007 Liston A, Siggs OM, Goodnow CC. Tracing the action of IL-2 in tolerance to islet-specific antigen Immunology and Cell Biology. 85: 338-342. PMID 17372610 DOI: 10.1038/sj.icb.7100049  0.44
2007 Goodnow CC, Campbell JA, Rui L, Vinuesa CG. Tolerance mechanisms in the late phase of the antibody response. Advances in Experimental Medicine and Biology. 596: 163-8. PMID 17338185 DOI: 10.1007/0-387-46530-8_15  0.44
2007 Liston A, Hardy K, Pittelkow Y, Wilson SR, Makaroff LE, Fahrer AM, Goodnow CC. Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: Genomic analysis by mRNA profiling Genome Biology. 8. PMID 17239257 DOI: 10.1186/gb-2007-8-1-r12  0.44
2007 Li G, Vega R, Nelms K, Gekakis N, Goodnow C, McNamara P, Wu H, Hong NA, Glynne R. A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence. Plos Genetics. 3: e8. PMID 17206865 DOI: 10.1371/journal.pgen.0030008  0.44
2007 Britton WJ, Casanova JL, Foote S, Goodnow CC, Gros P, Hume D, Karupiah G, Mackay C, Morahan G, Turner S, Young D. Discussion Novartis Foundation Symposium. 281: 177-180.  0.44
2007 Goodnow C. Closing remarks Novartis Foundation Symposium. 281: 208-209.  0.44
2007 Goodnow CC, Maizels RM, Hume D, Kaufman J, Schönbach C, Gros P, Britton WJ. General discussion I Novartis Foundation Symposium. 281: 50-53.  0.44
2007 Goodnow C. Chair's introduction Novartis Foundation Symposium. 281: 1.  0.44
2007 Goodnow CC. Nossal and Pike 1975: A turning point in the effort to define self-tolerance mechanisms Journal of Immunology. 179: 5617-5618.  0.44
2006 Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, et al. Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proceedings of the National Academy of Sciences of the United States of America. 103: 16442-7. PMID 17062753 DOI: 10.1073/pnas.0607872103  0.44
2006 Rui L, Healy JI, Blasioli J, Goodnow CC. ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 177: 5337-46. PMID 17015719  0.44
2006 Manderson AP, Quah B, Botto M, Goodnow CC, Walport MJ, Parish CR. A novel mechanism for complement activation at the surface of B cells following antigen binding. Journal of Immunology (Baltimore, Md. : 1950). 177: 5155-62. PMID 17015700  0.44
2006 Gray DH, Seach N, Ueno T, Milton MK, Liston A, Lew AM, Goodnow CC, Boyd RL. Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood. 108: 3777-85. PMID 16896157 DOI: 10.1182/blood-2006-02-004531  0.44
2006 Cook MC, Vinuesa CG, Goodnow CC. ENU-mutagenesis: insight into immune function and pathology. Current Opinion in Immunology. 18: 627-33. PMID 16889948 DOI: 10.1016/j.coi.2006.07.011  0.44
2006 Bléry M, Tze L, Miosge LA, Jun JE, Goodnow CC. Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy. The Journal of Experimental Medicine. 203: 1773-83. PMID 16801401 DOI: 10.1084/jem.20060552  0.44
2006 Goodnow CC. Immunology. Discriminating microbe from self suffers a double toll. Science (New York, N.Y.). 312: 1606-8. PMID 16778043 DOI: 10.1126/science.1129797  0.44
2006 Nijnik A, Ferry H, Lewis G, Rapsomaniki E, Leung JC, Daser A, Lambe T, Goodnow CC, Cornall RJ. Spontaneous B cell hyperactivity in autoimmune-prone MRL mice. International Immunology. 18: 1127-37. PMID 16735376 DOI: 10.1093/intimm/dxl047  0.44
2006 Rui L, Goodnow CC. Lymphoma and the control of B cell growth and differentiation. Current Molecular Medicine. 6: 291-308. PMID 16712476 DOI: 10.2174/156652406776894563  0.44
2006 Hoyne GF, Goodnow CC. The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity. Immunological Reviews. 210: 27-39. PMID 16623762 DOI: 10.1111/j.0105-2896.2006.00363.x  0.44
2006 Arsov T, Larter CZ, Nolan CJ, Petrovsky N, Goodnow CC, Teoh NC, Yeh MM, Farrell GC. Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice. Biochemical and Biophysical Research Communications. 342: 1152-9. PMID 16516152 DOI: 10.1016/j.bbrc.2006.02.032  0.44
2006 Arsov T, Silva DG, O'Bryan MK, Sainsbury A, Lee NJ, Kennedy C, Manji SS, Nelms K, Liu C, Vinuesa CG, de Kretser DM, Goodnow CC, Petrovsky N. Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Molecular Endocrinology (Baltimore, Md.). 20: 1610-22. PMID 16513793 DOI: 10.1210/me.2005-0494  0.44
2005 Kennedy CL, O'Connor AE, Sanchez-Partida LG, Holland MK, Goodnow CC, de Kretser DM, O'Bryan MK. A repository of ENU mutant mouse lines and their potential for male fertility research. Molecular Human Reproduction. 11: 871-80. PMID 16421219 DOI: 10.1093/molehr/gah251  0.44
2005 Ferry H, Crockford TL, Cockford TL, Silver K, Rust N, Goodnow CC, Cornall RJ. Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival. European Journal of Immunology. 35: 3655-63. PMID 16278813 DOI: 10.1002/eji.200535247  0.44
2005 Papathanasiou P, Goodnow CC. Connecting mammalian genome with phenome by ENU mouse mutagenesis: gene combinations specifying the immune system. Annual Review of Genetics. 39: 241-62. PMID 16053407 DOI: 10.1146/annurev.genet.39.110304.095817  0.44
2005 Miosge LA, Goodnow CC. Genes, pathways and checkpoints in lymphocyte development and homeostasis. Immunology and Cell Biology. 83: 318-35. PMID 16033527 DOI: 10.1111/j.1440-1711.2005.01353.x  0.44
2005 Liston A, Goodnow CC. Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity. Novartis Foundation Symposium. 267: 180-92; discussion 1. PMID 15999807  0.44
2005 Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature. 435: 590-7. PMID 15931211 DOI: 10.1038/nature03724  0.44
2005 Vinuesa CG, Cook MC, Angelucci C, Athanasopoulos V, Rui L, Hill KM, Yu D, Domaschenz H, Whittle B, Lambe T, Roberts IS, Copley RR, Bell JI, Cornall RJ, Goodnow CC. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature. 435: 452-8. PMID 15917799 DOI: 10.1038/nature03555  0.44
2005 Liston A, Lesage S, Gray DH, Boyd RL, Goodnow CC. Genetic lesions in T-cell tolerance and thresholds for autoimmunity. Immunological Reviews. 204: 87-101. PMID 15790352 DOI: 10.1111/j.0105-2896.2005.00253.x  0.44
2005 Abbas AK, Cookson W, Foote SJ, Goldstein DB, Goodnow CC, Hafler DA, Kere J, Kuchroo VK, Rao A, Seed B, Lineberger JT, Umetsu D. Discussion Novartis Foundation Symposium. 267: 52-56.  0.44
2004 Liston A, Lesage S, Gray DH, O'Reilly LA, Strasser A, Fahrer AM, Boyd RL, Wilson J, Baxter AG, Gallo EM, Crabtree GR, Peng K, Wilson SR, Goodnow CC. Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity. 21: 817-30. PMID 15589170 DOI: 10.1016/j.immuni.2004.10.014  0.44
2004 Liston A, Gray DH, Lesage S, Fletcher AL, Wilson J, Webster KE, Scott HS, Boyd RL, Peltonen L, Goodnow CC. Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. The Journal of Experimental Medicine. 200: 1015-26. PMID 15492124 DOI: 10.1084/jem.20040581  0.44
2004 Vinuesa CG, Goodnow CC. Illuminating autoimmune regulators through controlled variation of the mouse genome sequence. Immunity. 20: 669-79. PMID 15189733 DOI: 10.1016/j.immuni.2004.05.012  0.44
2003 Socha L, Silva D, Lesage S, Goodnow C, Petrovsky N. The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of β cell death Annals of the New York Academy of Sciences. 1005: 178-183. PMID 14679055 DOI: 10.1196/annals.1288.022  0.44
2003 Jun JE, Goodnow CC. Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. Nature Immunology. 4: 1057-64. PMID 14586424 DOI: 10.1038/ni1001  0.44
2003 Jun JE, Wilson LE, Vinuesa CG, Lesage S, Blery M, Miosge LA, Cook MC, Kucharska EM, Hara H, Penninger JM, Domashenz H, Hong NA, Glynne RJ, Nelms KA, Goodnow CC. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity. 18: 751-62. PMID 12818157 DOI: 10.1016/S1074-7613(03)00141-9  0.44
2003 Rui L, Vinuesa CG, Blasioli J, Goodnow CC. Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling. Nature Immunology. 4: 594-600. PMID 12740574 DOI: 10.1038/ni924  0.44
2003 Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nature Immunology. 4: 350-4. PMID 12612579 DOI: 10.1038/ni906  0.44
2002 Vinuesa CG, Cook MC, Cooke MP, Maclennan IC, Goodnow CC. Analysis of B cell memory formation using DNA microarrays. Annals of the New York Academy of Sciences. 975: 33-45. PMID 12538152  0.44
2002 Lesage S, Hartley SB, Akkaraju S, Wilson J, Townsend M, Goodnow CC. Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes. The Journal of Experimental Medicine. 196: 1175-88. PMID 12417628 DOI: 10.1084/jem.20020735  0.44
2002 Miosge LA, Blasioli J, Blery M, Goodnow CC. Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor κB2 in regulating circulating B cell numbers Journal of Experimental Medicine. 196: 1113-1119. PMID 12391023 DOI: 10.1084/jem.20020959  0.44
2002 Prasad SJ, Goodnow CC. Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo International Immunology. 14: 677-684. PMID 12039919  0.44
2002 Vinuesa CG, Goodnow CC. DNA drives autoimmunity Nature. 416: 595-598. PMID 11948338 DOI: 10.1038/416595a  0.44
2002 Prasad SJ, Goodnow CC. Intrinsic in vitro abnormalities in dendritic cell generation caused by non-MHC non-obese diabetic genes Immunology and Cell Biology. 80: 198-206. PMID 11940121 DOI: 10.1046/j.1440-1711.2002.01074.x  0.44
2002 Loy AL, Goodnow CC. Novel approaches for identifying genes regulating lymphocyte development and function Current Opinion in Immunology. 14: 260-265. PMID 11869902 DOI: 10.1016/S0952-7915(02)00331-X  0.44
2002 Blasioli J, Goodnow CC. Lyn/CD22/SHP-1 and their importance in autoimmunity Current Directions in Autoimmunity. 5: 151-160. PMID 11826756  0.44
2002 Martin SW, Goodnow CC. Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory Nature Immunology. 3: 182-188. PMID 11812996 DOI: 10.1038/ni752  0.44
2001 Nelms KA, Goodnow CC. Genome-wide ENU mutagenesis to reveal immune regulators Immunity. 15: 409-418. PMID 11567631 DOI: 10.1016/S1074-7613(01)00199-6  0.44
2001 Lesage S, Goodnow CC. Organ-specific autoimmune disease: A deficiency of tolerogenic stimulation Journal of Experimental Medicine. 194: F31-F36. PMID 11535640  0.44
2001 Goodnow CC, Glynne R, Akkaraju S, Rayner J, Mack D, Healy JI, Chaudhry S, Miosge L, Wilson L, Papathanasiou P, Loy A. Autoimmunity, self-tolerance and immune homeostasis: From whole animal phenotypes to molecular pathways Advances in Experimental Medicine and Biology. 490: 33-40. PMID 11505972  0.44
2001 Goodnow CC. Pathways for self-tolerance and the treatment of autoimmune diseases Lancet. 357: 2115-2121. PMID 11445125 DOI: 10.1016/S0140-6736(00)05185-0  0.44
2001 Fahrer AM, Bazan JF, Papathanasiou P, Nelms KA, Goodnow CC. A genomic view of immunology Nature. 409: 836-838. PMID 11237003 DOI: 10.1038/35057020  0.44
2001 Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M, Camper S, Carlson G, Copeland N, Eppig J, Fletcher C, Frankel WN, Ganten D, Goldowitz D, Goodnow C, et al. Sequence interpretation. Functional annotation of mouse genome sequences. Science (New York, N.Y.). 291: 1251-5. PMID 11233449 DOI: 10.1126/science.1058244  0.44
2001 Townsend SE, Goodnow CC, Cornall RJ. Single epitope multiple staining to detect ultralow frequency B cells Journal of Immunological Methods. 249: 137-146. PMID 11226471 DOI: 10.1016/S0022-1759(00)00352-5  0.44
2000 Glynne R, Ghandour G, Rayner J, Mack DH, Goodnow CC. B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays Immunological Reviews. 176: 216-246. PMID 11043780  0.44
2000 Weintraub BC, Jun JE, Bishop AC, Shokat KM, Thomas ML, Goodnow CC. Entry of B cell receptor into signaling domains is inhibited in tolerant B cells. The Journal of Experimental Medicine. 191: 1443-8. PMID 10770810  1
2000 Pogue SL, Goodnow CC. Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)G1 or IgM/IgG1 tail antigen receptors Journal of Experimental Medicine. 191: 1031-1043. PMID 10727464 DOI: 10.1084/jem.191.6.1031  0.44
2000 Glynne RJ, Ghandour G, Goodnow CC. Genomic-scale gene expression analysis of lymphocyte growth, tolerance and malignancy Current Opinion in Immunology. 12: 210-214. PMID 10712948 DOI: 10.1016/S0952-7915(99)00076-X  0.44
2000 Glynne R, Akkaraju S, Healy JI, Rayner J, Goodnow CC, Mack DH. How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis Nature. 403: 672-676. PMID 10688206 DOI: 10.1038/35001102  0.44
2000 Cornall RJ, Cheng AM, Pawson T, Goodnow CC. Role of Syk in B-cell development and antigen-receptor signaling Proceedings of the National Academy of Sciences of the United States of America. 97: 1713-1718. PMID 10677523 DOI: 10.1073/pnas.97.4.1713  0.44
2000 Martin S, Goodnow C. Memory needs no reminders Nature. 407: 576-577. DOI: 10.1038/35036673  0.44
1999 Goodnow CC, Glynne R, Mack D, Weintraub B, Rathmell J, Healy JI, Chaudhry S, Miosge L, Loy A, Wilson L. Mechanisms of self-tolerance and autoimmunity: from whole-animal phenotypes to molecular pathways. Cold Spring Harbor Symposia On Quantitative Biology. 64: 313-22. PMID 11232301  0.44
1999 Cornall RJ, Goodnow CC, Cyster JG. Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway Current Topics in Microbiology and Immunology. 244: 57-68. PMID 10453649  0.44
1999 Townsend SE, Weintraub BC, Goodnow CC. Growing up on the streets: why B-cell development differs from T-cell development. Immunology Today. 20: 217-20. PMID 10322300 DOI: 10.1016/S0167-5699(98)01440-6  0.44
1998 Goodnow CC. Cancer immunotherapy: New leads on an elusive goal Medical Journal of Australia. 169: 570-571. PMID 9887894  0.44
1998 Prodeus AP, Goerg S, Shen LM, Pozdnyakova OO, Chu L, Alicot EM, Goodnow CC, Carroll MC. A critical role for complement in maintenance of self-tolerance Immunity. 9: 721-731. PMID 9846493  0.44
1998 Rathmell JC, Goodnow CC. The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment Immunology and Cell Biology. 76: 387-394. PMID 9797457 DOI: 10.1046/j.1440-1711.1998.00774.x  0.44
1998 Ying H, Healy JI, Goodnow CC, Parnes JR. Regulation of mouse CD72 gene expression during B lymphocyte development Journal of Immunology. 161: 4760-4767. PMID 9794407  0.44
1998 Healy JI, Dolmetsch RE, Lewis RS, Goodnow CC. Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes. Novartis Foundation Symposium. 215: 137-44; discussion 1. PMID 9760576  0.44
1998 Cornall RJ, Goodnow CC. B cell antigen receptor signalling in the balance of tolerance and immunity Novartis Foundation Symposium. 215: 21-30; discussion 30. PMID 9760569  0.44
1998 Weintraub BC, Goodnow CC. Immune Responses: costimulatory receptors have their say. Current Biology : Cb. 8: R575-7. PMID 9707395  0.44
1998 Rathmell JC, Fournier S, Weintraub BC, Allison JP, Goodnow CC. Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. The Journal of Experimental Medicine. 188: 651-9. PMID 9705947 DOI: 10.1084/jem.188.4.651  0.44
1998 Fang W, Weintraub BC, Dunlap B, Garside P, Pape KA, Jenkins MK, Goodnow CC, Mueller DL, Behrens TW. Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. Immunity. 9: 35-45. PMID 9697834 DOI: 10.1016/S1074-7613(00)80586-5  0.44
1998 Healy JI, Goodnow CC. Positive versus negative signaling by lymphocyte antigen receptors Annual Review of Immunology. 16: 645-670. PMID 9597145 DOI: 10.1146/annurev.immunol.16.1.645  0.44
1998 Cornall RJ, Cyster JG, Hibbs ML, Dunn AR, Otipoby KL, Clark EA, Goodnow CC. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity. 8: 497-508. PMID 9586639 DOI: 10.1016/S1074-7613(00)80554-3  0.44
1998 Townsend SE, Goodnow CC. Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo Journal of Experimental Medicine. 187: 1611-1621. PMID 9584139 DOI: 10.1084/jem.187.10.1611  0.44
1998 Fischer MB, Goerg S, Shen L, Prodeus AP, Goodnow CC, Kelsoe G, Carroll MC. Dependence of germinal center B cells on expression of CD21/CD35 for survival Science. 280: 582-585. PMID 9554848 DOI: 10.1126/science.280.5363.582  0.44
1998 Schmidt KN, Hsu CW, Griffin CT, Goodnow CC, Cyster JG. Spontaneous follicular exclusion of SHP1-deficient B cells is conditional on the presence of competitor wild-type B cells. The Journal of Experimental Medicine. 187: 929-37. PMID 9500795 DOI: 10.1084/jem.187.6.929  0.44
1997 Akkaraju S, Canaan K, Goodnow CC. Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells Journal of Experimental Medicine. 186: 2005-2012. PMID 9396769 DOI: 10.1084/jem.186.12.2005  0.44
1997 Inaoki M, Sato S, Weintraub BC, Goodnow CC, Tedder TF. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. The Journal of Experimental Medicine. 186: 1923-31. PMID 9382890 DOI: 10.1084/jem.186.11.1923  0.44
1997 Timmerman LA, Healy JI, Ho SN, Chen L, Goodnow CC, Crabtree GR. Redundant expression but selective utilization of nuclear factor of activated T cells family members. Journal of Immunology (Baltimore, Md. : 1950). 159: 2735-40. PMID 9300694  0.44
1997 Goodnow CC. Balancing immunity, autoimmunity, and self-tolerance Annals of the New York Academy of Sciences. 815: 55-66. PMID 9186639 DOI: 10.1111/j.1749-6632.1997.tb52044.x  0.44
1997 Goodnow CC. Glimpses into the balance between immunity and self-tolerance Ciba Foundation Symposia. 190-207. PMID 9107422  0.44
1995 Shokat KM, Goodnow CC. Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature. 375: 334-8. PMID 7753200 DOI: 10.1038/375334a0  1
1994 Cooke MP, Heath AW, Shokat KM, Zeng Y, Finkelman FD, Linsley PS, Howard M, Goodnow CC. Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. The Journal of Experimental Medicine. 179: 425-38. PMID 8294858  0.44
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