Aneel K. Aggarwal - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Protein-nucleic acid interactions: studied by X-ray crystallography and other biophysical methods
Website:
http://www.mountsinai.org/profiles/aneel-k-aggarwal?id=0000072500001497255792

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Jain R, Coloma J, García-Sastre A, Aggarwal AK. Structure of the NS3 helicase from Zika virus. Nature Structural & Molecular Biology. PMID 27399257 DOI: 10.1038/nsmb.3258  0.32
2016 Callahan SJ, Luyten YA, Gupta YK, Wilson GG, Roberts RJ, Morgan RD, Aggarwal AK. Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities. Plos Biology. 14: e1002442. PMID 27082731 DOI: 10.1371/journal.pbio.1002442  0.32
2016 Coloma J, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Human DNA polymerase α in binary complex with a DNA:DNA template-primer. Scientific Reports. 6: 23784. PMID 27032819 DOI: 10.1038/srep23784  0.32
2015 Gupta YK, Chan SH, Xu SY, Aggarwal AK. Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I. Nature Communications. 6: 7363. PMID 26067164 DOI: 10.1038/ncomms8363  0.32
2014 Jain R, Rajashankar KR, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Crystal structure of yeast DNA polymerase ε catalytic domain. Plos One. 9: e94835. PMID 24733111 DOI: 10.1371/journal.pone.0094835  0.32
2014 Jain R, Vanamee ES, Dzikovski BG, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK. An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε. Journal of Molecular Biology. 426: 301-8. PMID 24144619 DOI: 10.1016/j.jmb.2013.10.015  0.32
2013 Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, Aggarwal AK, Rosenfeld MG. Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell. 155: 1581-95. PMID 24360279 DOI: 10.1016/j.cell.2013.10.056  0.32
2013 Gómez-Llorente Y, Malik R, Jain R, Choudhury JR, Johnson RE, Prakash L, Prakash S, Ubarretxena-Belandia I, Aggarwal AK. The architecture of yeast DNA polymerase ζ. Cell Reports. 5: 79-86. PMID 24120860 DOI: 10.1016/j.celrep.2013.08.046  0.32
2012 Reddy EP, Aggarwal AK. The ins and outs of bcr-abl inhibition. Genes & Cancer. 3: 447-54. PMID 23226582 DOI: 10.1177/1947601912462126  0.32
2012 De Ioannes P, Malu S, Cortes P, Aggarwal AK. Structural basis of DNA ligase IV-Artemis interaction in nonhomologous end-joining. Cell Reports. 2: 1505-12. PMID 23219551 DOI: 10.1016/j.celrep.2012.11.004  0.32
2012 Ferrage F, Dutta K, Nistal-Villán E, Patel JR, Sánchez-Aparicio MT, De Ioannes P, Buku A, Aseguinolaza GG, García-Sastre A, Aggarwal AK. Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation. Structure (London, England : 1993). 20: 2048-61. PMID 23063562 DOI: 10.1016/j.str.2012.09.003  0.32
2012 Ummat A, Rechkoblit O, Jain R, Roy Choudhury J, Johnson RE, Silverstein TD, Buku A, Lone S, Prakash L, Prakash S, Aggarwal AK. Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Nature Structural & Molecular Biology. 19: 628-32. PMID 22562137 DOI: 10.1038/nsmb.2295  0.32
2012 Gupta YK, Yang L, Chan SH, Samuelson JC, Xu SY, Aggarwal AK. Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering. Journal of Molecular Biology. 420: 261-8. PMID 22560991 DOI: 10.1016/j.jmb.2012.04.026  0.32
2012 Malu S, De Ioannes P, Kozlov M, Greene M, Francis D, Hanna M, Pena J, Escalante CR, Kurosawa A, Erdjument-Bromage H, Tempst P, Adachi N, Vezzoni P, Villa A, Aggarwal AK, et al. Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. The Journal of Experimental Medicine. 209: 955-63. PMID 22529269 DOI: 10.1084/jem.20111437  0.32
2012 Ummat A, Silverstein TD, Jain R, Buku A, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Human DNA polymerase η is pre-aligned for dNTP binding and catalysis. Journal of Molecular Biology. 415: 627-34. PMID 22154937 DOI: 10.1016/j.jmb.2011.11.038  0.32
2012 Xu SY, Nugent RL, Kasamkattil J, Fomenkov A, Gupta Y, Aggarwal A, Wang X, Li Z, Zheng Y, Morgan R. Characterization of type II and III restriction-modification systems from Bacillus cereus strains ATCC 10987 and ATCC 14579. Journal of Bacteriology. 194: 49-60. PMID 22037402 DOI: 10.1128/JB.06248-11  0.32
2011 Callahan SJ, Morgan RD, Jain R, Townson SA, Wilson GG, Roberts RJ, Aggarwal AK. Crystallization and preliminary crystallographic analysis of the type IIL restriction enzyme MmeI in complex with DNA. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1262-5. PMID 22102043 DOI: 10.1107/S1744309111028041  0.32
2011 De Ioannes P, Escalante CR, Aggarwal AK. Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Research. 39: 7300-7. PMID 21596780 DOI: 10.1093/nar/gkr325  0.32
2011 Vasquez-Del Carpio R, Silverstein TD, Lone S, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. Journal of Molecular Biology. 408: 252-61. PMID 21354175 DOI: 10.1016/j.jmb.2011.02.042  0.32
2011 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. Journal of Molecular Biology. 406: 18-28. PMID 21167175 DOI: 10.1016/j.jmb.2010.12.016  0.32
2011 Vanamee ES, Viadiu H, Chan SH, Ummat A, Hartline AM, Xu SY, Aggarwal AK. Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI. Nucleic Acids Research. 39: 712-9. PMID 20833632 DOI: 10.1093/nar/gkq779  0.32
2010 Silverstein TD, Jain R, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η. Structure (London, England : 1993). 18: 1463-70. PMID 21070945 DOI: 10.1016/j.str.2010.08.019  0.32
2010 Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 466: 508-12. PMID 20622854 DOI: 10.1038/nature09272  0.32
2010 Silverstein TD, Johnson RE, Jain R, Prakash L, Prakash S, Aggarwal AK. Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature. 465: 1039-43. PMID 20577207 DOI: 10.1038/nature09104  0.32
2010 Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A. Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production. The Journal of Biological Chemistry. 285: 20252-61. PMID 20406818 DOI: 10.1074/jbc.M109.089912  0.32
2009 Jain R, Hammel M, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. Journal of Molecular Biology. 394: 377-82. PMID 19818796 DOI: 10.1016/j.jmb.2009.09.066  0.32
2009 Swan MK, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Nature Structural & Molecular Biology. 16: 979-86. PMID 19718023 DOI: 10.1038/nsmb.1663  0.32
2009 Jain R, Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Replication across template T/U by human DNA polymerase-iota. Structure (London, England : 1993). 17: 974-80. PMID 19604477 DOI: 10.1016/j.str.2009.04.011  0.32
2009 Vasquez-Del Carpio R, Silverstein TD, Lone S, Swan MK, Choudhury JR, Johnson RE, Prakash S, Prakash L, Aggarwal AK. Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Plos One. 4: e5766. PMID 19492058 DOI: 10.1371/journal.pone.0005766  0.32
2009 Swan MK, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Structure of the human Rev1-DNA-dNTP ternary complex. Journal of Molecular Biology. 390: 699-709. PMID 19464298 DOI: 10.1016/j.jmb.2009.05.026  0.32
2009 Gupta YK, Lee TH, Edwards TA, Escalante CR, Kadyrova LY, Wharton RP, Aggarwal AK. Co-occupancy of two Pumilio molecules on a single hunchback NRE. Rna (New York, N.Y.). 15: 1029-35. PMID 19372537 DOI: 10.1261/rna.1327609  0.32
2009 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. DNA synthesis across an abasic lesion by human DNA polymerase iota. Structure (London, England : 1993). 17: 530-7. PMID 19368886 DOI: 10.1016/j.str.2009.02.015  0.32
2008 Gupta YK, Nair DT, Wharton RP, Aggarwal AK. Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. Structure (London, England : 1993). 16: 549-57. PMID 18328718 DOI: 10.1016/j.str.2008.01.006  0.32
2008 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Structure (London, England : 1993). 16: 239-45. PMID 18275815 DOI: 10.1016/j.str.2007.12.009  0.32
2007 Joshi R, Passner JM, Rohs R, Jain R, Sosinsky A, Crickmore MA, Jacob V, Aggarwal AK, Honig B, Mann RS. Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell. 131: 530-43. PMID 17981120 DOI: 10.1016/j.cell.2007.09.024  0.32
2007 Escalante CR, Nistal-Villán E, Shen L, García-Sastre A, Aggarwal AK. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Molecular Cell. 26: 703-16. PMID 17560375 DOI: 10.1016/j.molcel.2007.04.022  0.32
2007 Vanamee ES, Berriman J, Aggarwal AK. An EM view of the FokI synaptic complex by single particle analysis. Journal of Molecular Biology. 370: 207-12. PMID 17524420 DOI: 10.1016/j.jmb.2007.04.066  0.32
2007 Townson SA, Samuelson JC, Bao Y, Xu SY, Aggarwal AK. BstYI bound to noncognate DNA reveals a "hemispecific" complex: implications for DNA scanning. Structure (London, England : 1993). 15: 449-59. PMID 17437717 DOI: 10.1016/j.str.2007.03.002  0.32
2007 Niv MY, Ripoll DR, Vila JA, Liwo A, Vanamee ES, Aggarwal AK, Weinstein H, Scheraga HA. Topology of Type II REases revisited; structural classes and the common conserved core. Nucleic Acids Research. 35: 2227-37. PMID 17369272 DOI: 10.1093/nar/gkm045  0.32
2007 Lone S, Townson SA, Uljon SN, Johnson RE, Brahma A, Nair DT, Prakash S, Prakash L, Aggarwal AK. Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Molecular Cell. 25: 601-14. PMID 17317631 DOI: 10.1016/j.molcel.2007.01.018  0.32
2006 Wharton RP, Aggarwal AK. mRNA regulation by Puf domain proteins. Science's Stke : Signal Transduction Knowledge Environment. 2006: pe37. PMID 17003467 DOI: 10.1126/stke.3542006pe37  0.32
2006 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nature Structural & Molecular Biology. 13: 619-25. PMID 16819516 DOI: 10.1038/nsmb1118  0.32
2006 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure (London, England : 1993). 14: 749-55. PMID 16615915 DOI: 10.1016/j.str.2006.01.010  0.32
2006 Edwards TA, Butterwick JA, Zeng L, Gupta YK, Wang X, Wharton RP, Palmer AG, Aggarwal AK. Solution structure of the Vts1 SAM domain in the presence of RNA. Journal of Molecular Biology. 356: 1065-72. PMID 16405996 DOI: 10.1016/j.jmb.2005.12.004  0.32
2005 Vanamee ES, Viadiu H, Kucera R, Dorner L, Picone S, Schildkraut I, Aggarwal AK. A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA. The Embo Journal. 24: 4198-208. PMID 16308566 DOI: 10.1038/sj.emboj.7600880  0.32
2005 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Structure (London, England : 1993). 13: 1569-77. PMID 16216587 DOI: 10.1016/j.str.2005.08.010  0.32
2005 Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ. Proximity-induced activation of human Cdc34 through heterologous dimerization. Proceedings of the National Academy of Sciences of the United States of America. 102: 15053-8. PMID 16210246 DOI: 10.1073/pnas.0507646102  0.32
2005 Nair DT, Johnson RE, Prakash L, Prakash S, Aggarwal AK. Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science (New York, N.Y.). 309: 2219-22. PMID 16195463 DOI: 10.1126/science.1116336  0.32
2005 Townson SA, Samuelson JC, Xu SY, Aggarwal AK. Implications for switching restriction enzyme specificities from the structure of BstYI bound to a BglII DNA sequence. Structure (London, England : 1993). 13: 791-801. PMID 15893669 DOI: 10.1016/j.str.2005.02.018  0.32
2005 Aggarwal AK, Doudna JA. Protein-nucleic acid interactions: Unlocking mysteries old and new Current Opinion in Structural Biology. 15: 65-67. DOI: 10.1016/j.sbi.2005.01.017  0.32
2004 Yoon-Robarts M, Blouin AG, Bleker S, Kleinschmidt JA, Aggarwal AK, Escalante CR, Linden RM. Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2. The Journal of Biological Chemistry. 279: 50472-81. PMID 15371437 DOI: 10.1074/jbc.M403900200  0.32
2004 James JA, Aggarwal AK, Linden RM, Escalante CR. Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proceedings of the National Academy of Sciences of the United States of America. 101: 12455-60. PMID 15310852 DOI: 10.1073/pnas.0403454101  0.32
2004 Uljon SN, Johnson RE, Edwards TA, Prakash S, Prakash L, Aggarwal AK. Crystal structure of the catalytic core of human DNA polymerase kappa. Structure (London, England : 1993). 12: 1395-404. PMID 15296733 DOI: 10.1016/j.str.2004.05.011  0.32
2004 Nair DT, Johnson RE, Prakash S, Prakash L, Aggarwal AK. Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature. 430: 377-80. PMID 15254543 DOI: 10.1038/nature02692  0.32
2004 Townson SA, Samuelson JC, Vanamee ES, Edwards TA, Escalante CR, Xu SY, Aggarwal AK. Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII. Journal of Molecular Biology. 338: 725-33. PMID 15099740 DOI: 10.1016/j.jmb.2004.02.074  0.32
2004 Trincao J, Johnson RE, Wolfle WT, Escalante CR, Prakash S, Prakash L, Aggarwal AK. Dpo4 is hindered in extending a G.T mismatch by a reverse wobble. Nature Structural & Molecular Biology. 11: 457-62. PMID 15077104 DOI: 10.1038/nsmb755  0.32
2004 Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell. 116: 511-26. PMID 14980219 DOI: 10.1016/S0092-8674(04)00133-3  0.32
2003 Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 426: 247-54. PMID 14628042 DOI: 10.1038/nature02083  0.32
2003 Vanamee ES, Hsieh Pc, Zhu Z, Yates D, Garman E, Xu Sy, Aggarwal AK. Glucocorticoid receptor-like Zn(Cys)4 motifs in BslI restriction endonuclease. Journal of Molecular Biology. 334: 595-603. PMID 14623197 DOI: 10.1016/j.jmb.2003.09.043  0.32
2003 Edwards TA, Wilkinson BD, Wharton RP, Aggarwal AK. Model of the brain tumor-Pumilio translation repressor complex. Genes & Development. 17: 2508-13. PMID 14561773 DOI: 10.1101/gad.1119403  0.32
2003 James JA, Escalante CR, Yoon-Robarts M, Edwards TA, Linden RM, Aggarwal AK. Crystal structure of the SF3 helicase from adeno-associated virus type 2. Structure (London, England : 1993). 11: 1025-35. PMID 12906833 DOI: 10.1016/S0969-2126(03)00152-7  0.32
2003 Viadiu H, Vanamee ES, Jacobson EM, Schildkraut I, Aggarwal AK. Crystallization of restriction endonuclease SfiI in complex with DNA. Acta Crystallographica. Section D, Biological Crystallography. 59: 1493-5. PMID 12876363 DOI: 10.1107/S0907444903011910  0.32
2003 Green JB, Gardner CD, Wharton RP, Aggarwal AK. RNA recognition via the SAM domain of Smaug. Molecular Cell. 11: 1537-48. PMID 12820967 DOI: 10.1016/S1097-2765(03)00178-3  0.32
2003 Sun J, Viadiu H, Aggarwal AK, Weinstein H. Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex. Biophysical Journal. 84: 3317-25. PMID 12719261 DOI: 10.1016/S0006-3495(03)70056-3  0.32
2002 Escalante CR, Brass AL, Pongubala JM, Shatova E, Shen L, Singh H, Aggarwal AK. Crystal structure of PU.1/IRF-4/DNA ternary complex. Molecular Cell. 10: 1097-105. PMID 12453417  0.32
2002 Kumar V, Carlson JE, Ohgi KA, Edwards TA, Rose DW, Escalante CR, Rosenfeld MG, Aggarwal AK. Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Molecular Cell. 10: 857-69. PMID 12419229 DOI: 10.1016/S1097-2765(02)00650-0  0.32
2002 Dean KA, Aggarwal AK, Wharton RP. Translational repressors in Drosophila. Trends in Genetics : Tig. 18: 572-7. PMID 12414187 DOI: 10.1016/S0168-9525(02)02792-0  0.32
2002 Green JB, Edwards TA, Trincao J, Escalante CR, Wharton RP, Aggarwal AK. Crystallization and characterization of Smaug: a novel RNA-binding motif. Biochemical and Biophysical Research Communications. 297: 1085-8. PMID 12372396 DOI: 10.1016/S0006-291X(02)02327-6  0.32
2002 Escalante CR, Shen L, Escalante MC, Brass AL, Edwards TA, Singh H, Aggarwal AK. Crystallization and characterization of PU.1/IRF-4/DNA ternary complex. Journal of Structural Biology. 139: 55-9. PMID 12372320 DOI: 10.1016/S1047-8477(02)00514-2  0.32
2002 Escalante CR, Shen L, Thanos D, Aggarwal AK. Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter. Structure (London, England : 1993). 10: 383-91. PMID 12005436 DOI: 10.1016/S0969-2126(02)00723-2  0.32
2001 Vanamee ES, Santagata S, Aggarwal AK. FokI requires two specific DNA sites for cleavage. Journal of Molecular Biology. 309: 69-78. PMID 11491302 DOI: 10.1006/jmbi.2001.4635  0.32
2001 Edwards TA, Pyle SE, Wharton RP, Aggarwal AK. Structure of Pumilio reveals similarity between RNA and peptide binding motifs. Cell. 105: 281-9. PMID 11336677 DOI: 10.1016/S0092-8674(01)00318-X  0.32
2001 Yoon M, Smith DH, Ward P, Medrano FJ, Aggarwal AK, Linden RM. Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro. Journal of Virology. 75: 3230-9. PMID 11238849 DOI: 10.1128/JVI.75.7.3230-3239.2001  0.32
2001 Lukacs CM, Aggarwal AK. BglII and MunI: What a difference a base makes Current Opinion in Structural Biology. 11: 14-18. PMID 11179886 DOI: 10.1016/S0959-440X(00)00174-3  0.32
2001 Lukacs CM, Kucera R, Schildkraut I, Aggarwal AK. Structure of free BglII reveals an unprecedented scissor-like motion for opening an endonuclease Nature Structural Biology. 8: 126-130. PMID 11175900 DOI: 10.1038/84111  0.32
2000 Edwards TA, Trincao J, Escalante CR, Wharton RP, Aggarwal AK. Crystallization and characterization of Pumilo: a novel RNA binding protein. Journal of Structural Biology. 132: 251-4. PMID 11303521 DOI: 10.1006/jsbi.2000.4319  0.32
2000 Senger K, Merika M, Agalioti T, Yie J, Escalante CR, Chen G, Aggarwal AK, Thanos D. Gene repression by coactivator repulsion Molecular Cell. 6: 931-937. PMID 11090630  0.32
2000 Scully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carrière C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG. Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science (New York, N.Y.). 290: 1127-31. PMID 11073444 DOI: 10.1126/science.290.5494.1127  0.32
2000 Viadiu H, Aggarwal AK. Structure of BamHI bound to nonspecific DNA: A model for DNA sliding Molecular Cell. 5: 889-895. PMID 10882125 DOI: 10.1016/S1097-2765(00)80329-9  0.32
2000 Qiu L, Escalante CR, Aggarwal AK, Wilson PD, Burrow CR. Monomeric midkine induces tumor cell proliferation in the absence of cell-surface proteoglycan binding. Biochemistry. 39: 5977-87. PMID 10821669 DOI: 10.1021/bi991519e  0.32
2000 Viadiu H, Kucera R, Schildkraut I, Aggarwal AK. Crystallization of restriction endonuclease BamHI with nonspecific DNA Journal of Structural Biology. 130: 81-85. PMID 10806094 DOI: 10.1006/jsbi.2000.4235  0.32
2000 Lukacs CM, Kucera R, Schildkraut I, Aggarwal AK. Understanding the immutability of restriction enzymes: Crystal structure of Bg/II and its DNA substrate at 1.5 Å resolution Nature Structural Biology. 7: 134-140. PMID 10655616 DOI: 10.1038/72405  0.32
1999 Dhalluin C, Carlson JE, Zeng L, He C, Aggarwal AK, Zhou MM. 1H, 15N and 13C resonance assignments for the bromodomain of the histone acetyltransferase P/CAF. Journal of Biomolecular Nmr. 14: 291-2. PMID 10481282 DOI: 10.1023/A:1008334631802  0.32
1999 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG. Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 97: 587-98. PMID 10367888 DOI: 10.1016/S0092-8674(00)80770-9  0.32
1999 Dhalluin C, Carlson JE, Zeng L, He C, Aggarwal AK, Zhou MM. Structure and ligand of a histone acetyltransferase bromodomain. Nature. 399: 491-6. PMID 10365964 DOI: 10.1038/20974  0.32
1999 Passner JM, Ryoo HD, Shen L, Mann RS, Aggarwal AK. Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature. 397: 714-9. PMID 10067897 DOI: 10.1038/17833  0.32
1998 Viadiu H, Aggarwal AK. The role of metals in catalysis by the restriction endonuclease bamhi Nature Structural Biology. 5: 910-916. PMID 9783752 DOI: 10.1038/2352  0.32
1998 Xu L, Lavinsky RM, Dasen JS, Flynn SE, McInerney EM, Mullen TM, Heinzel T, Szeto D, Korzus E, Kurokawa R, Aggarwal AK, Rose DW, Glass CK, Rosenfeld MG. Signal-specific co-activator domain requirements for Pit-1 activation. Nature. 395: 301-6. PMID 9751061 DOI: 10.1038/26270  0.32
1998 Bitinaite J, Wah DA, Aggarwal AK, Schildkraut I. Foki dimerization is required for dna cleavage Proceedings of the National Academy of Sciences of the United States of America. 95: 10570-10575. PMID 9724744 DOI: 10.1073/pnas.95.18.10570  0.32
1998 Wah DA, Bitinaite J, Schildkraut I, Aggarwal AK. Structure of FokI has implications for DNA cleavage Proceedings of the National Academy of Sciences of the United States of America. 95: 10564-10569. PMID 9724743 DOI: 10.1073/pnas.95.18.10564  0.32
1998 Aggarwal AK, Wah DA. Novel site-specific DNA endonucleases Current Opinion in Structural Biology. 8: 19-25. PMID 9519292 DOI: 10.1016/S0959-440X(98)80005-5  0.32
1998 Escalante CR, Yie J, Thanos D, Aggarwal AK. Structure of IRF-1 with bound DNA reveals determinants of interferon regulation Nature. 391: 103-106. PMID 9422515 DOI: 10.1038/34224  0.32
1997 Escalante CR, Yie J, Thanos D, Aggarwal AK. Expression, purification, and co-crystallization of IRF-I bound to the interferon-β element PRDI Febs Letters. 414: 219-220. PMID 9315689 DOI: 10.1016/S0014-5793(97)00996-4  0.32
1997 Wah DA, Hirsch JA, Dorner LF, Schildkraut I, Aggarwal AK. Structure of the multimodular endonuclease FokI bound to DNA Nature. 388: 97-100. PMID 9214510 DOI: 10.1038/40446  0.32
1997 Aggarwal AK. Homing in on intron-encoded endonucleases Nature Structural Biology. 4: 423-424. PMID 9187644 DOI: 10.1038/nsb0697-423  0.32
1997 Hirsch JA, Wah DA, Dorner LF, Schildkraut I, Aggarwal AK. Crystallization and preliminary X-ray analysis of restriction endonuclease FokI bound to DNA Febs Letters. 403: 136-138. PMID 9042953 DOI: 10.1016/S0014-5793(97)00039-2  0.32
1997 Jacobson EM, Li P, Leon-del-Rio A, Rosenfeld MG, Aggarwal AK. Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes & Development. 11: 198-212. PMID 9009203  0.32
1996 Jacobson EM, Li P, Rosenfeld MG, Aggarwal AK. Crystallization and preliminary X-ray analysis of Pit-1 POU domain complexed to a 28 base pair DNA element. Proteins. 24: 263-5. PMID 8820493 DOI: 10.1002/(SICI)1097-0134(199602)24:2<263::AID-PROT14>3.0.CO;2-L  0.32
1995 Hirsch JA, Aggarwal AK. Structure of the Even-skipped homeodomain complexed to AT-rich DNA: New perspectives on homeodomain specificity Embo Journal. 14: 6280-6291. PMID 8557047  0.32
1995 Hirsch JA, Aggarwal AK. Purification, crystallization, and preliminary X-ray diffraction analysis of even-skipped homeodomain complexed to DNA Proteins: Structure, Function and Genetics. 21: 268-271. PMID 7784431 DOI: 10.1002/prot.340210311  0.32
1995 Aggarwal AK. Structure and function of restriction endonucleases Current Opinion in Structural Biology. 5: 11-19. PMID 7773740 DOI: 10.1016/0959-440X(95)80004-K  0.32
1995 Newman M, Strzelecka T, Dorner LF, Schildkraut I, Aggarwal AK. Structure of Bam HI endonuclease bound to DNA: Partial folding and unfolding on DNA binding Science. 269: 656-663. PMID 7624794  0.32
1993 Li P, He X, Gerrero MR, Mok M, Aggarwal A, Rosenfeld MG. Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Genes & Development. 7: 2483-96. PMID 8276233  0.32
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