Pieter C. Dorrestein - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Biochemistry, Chemical Biology, Mass spectrometry; Harvesting genomic information for therapeutics
Website:
http://www-chem.ucsd.edu/faculty/profiles/dorrestein_pieter_c.html

258 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Morton JT, Aksenov AA, Nothias LF, Foulds JR, Quinn RA, Badri MH, Swenson TL, Van Goethem MW, Northen TR, Vazquez-Baeza Y, Wang M, Bokulich NA, Watters A, Song SJ, Bonneau R, ... Dorrestein PC, et al. Learning representations of microbe-metabolite interactions. Nature Methods. PMID 31686038 DOI: 10.1038/s41592-019-0616-3  0.4
2019 McCall LI, Callewaert C, Zhu Q, Song SJ, Bouslimani A, Minich JJ, Ernst M, Ruiz-Calderon JF, Cavallin H, Pereira HS, Novoselac A, Hernandez J, Rios R, Branch OH, Blaser MJ, ... ... Dorrestein PC, et al. Home chemical and microbial transitions across urbanization. Nature Microbiology. PMID 31686026 DOI: 10.1038/s41564-019-0593-4  0.4
2019 Sanders JG, Nurk S, Salido RA, Minich J, Xu ZZ, Zhu Q, Martino C, Fedarko M, Arthur TD, Chen F, Boland BS, Humphrey GC, Brennan C, Sanders K, Gaffney J, ... ... Dorrestein PC, et al. Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads. Genome Biology. 20: 226. PMID 31672156 DOI: 10.1186/s13059-019-1834-9  0.64
2019 Cao L, Gurevich A, Alexander KL, Naman CB, Leão T, Glukhov E, Luzzatto-Knaan T, Vargas F, Quinn R, Bouslimani A, Nothias LF, Singh NK, Sanders JG, Benitez RAS, Thompson LR, ... ... Dorrestein PC, et al. MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. Cell Systems. PMID 31629686 DOI: 10.1016/j.cels.2019.09.004  0.6
2019 Melnik AV, Vázquez-Baeza Y, Aksenov AA, Hyde E, McAvoy AC, Wang M, da Silva RR, Protsyuk I, Wu JV, Bouslimani A, Lim YW, Luzzatto-Knaan T, Comstock W, Quinn RA, Wong R, ... ... Dorrestein PC, et al. Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis. Msystems. 4. PMID 31551401 DOI: 10.1128/mSystems.00375-19  0.64
2019 Yu HB, Glukhov E, Li Y, Iwasaki A, Gerwick L, Dorrestein PC, Jiao BH, Gerwick WH. Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium . Journal of Natural Products. PMID 31468974 DOI: 10.1021/acs.jnatprod.9b00549  0.56
2019 Gauglitz JM, Aceves CM, Aksenov AA, Aleti G, Almaliti J, Bouslimani A, Brown EA, Campeau A, Caraballo-Rodríguez AM, Chaar R, da Silva RR, Demko AM, Di Ottavio F, Elijah E, Ernst M, ... ... Dorrestein PC, et al. Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages. Food Chemistry. 302: 125290. PMID 31404873 DOI: 10.1016/j.foodchem.2019.125290  0.84
2019 Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, Al-Ghalith GA, Alexander H, Alm EJ, Arumugam M, Asnicar F, Bai Y, Bisanz JE, Bittinger K, Brejnrod A, Brislawn CJ, ... ... Dorrestein PC, et al. Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature Biotechnology. PMID 31399723 DOI: 10.1038/s41587-019-0252-6  0.84
2019 Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, Al-Ghalith GA, Alexander H, Alm EJ, Arumugam M, Asnicar F, Bai Y, Bisanz JE, Bittinger K, Brejnrod A, Brislawn CJ, ... ... Dorrestein PC, et al. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature Biotechnology. PMID 31341288 DOI: 10.1038/s41587-019-0209-9  0.84
2019 Ernst M, Nothias LF, van der Hooft JJJ, Silva RR, Saslis-Lagoudakis CH, Grace OM, Martinez-Swatson K, Hassemer G, Funez LA, Simonsen HT, Medema MH, Staerk D, Nilsson N, Lovato P, Dorrestein PC, et al. Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus L. Frontiers in Plant Science. 10: 846. PMID 31333695 DOI: 10.3389/fpls.2019.00846  0.4
2019 Ernst M, Kang KB, Caraballo-Rodríguez AM, Nothias LF, Wandy J, Chen C, Wang M, Rogers S, Medema MH, Dorrestein PC, van der Hooft JJJ. MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools. Metabolites. 9. PMID 31315242 DOI: 10.3390/metabo9070144  0.4
2019 Bouslimani A, da Silva R, Kosciolek T, Janssen S, Callewaert C, Amir A, Dorrestein K, Melnik AV, Zaramela LS, Kim JN, Humphrey G, Schwartz T, Sanders K, Brennan C, Luzzatto-Knaan T, ... ... Dorrestein PC, et al. The impact of skin care products on skin chemistry and microbiome dynamics. Bmc Biology. 17: 47. PMID 31189482 DOI: 10.1186/s12915-019-0660-6  0.4
2019 Nothias-Esposito M, Nothias LF, Da Silva RR, Retailleau P, Zhang Z, Leyssen P, Roussi F, Touboul D, Paolini J, Dorrestein PC, Litaudon M. Investigation of Premyrsinane and Myrsinane Esters in Euphorbia cupanii and Euphobia pithyusa with MS2LDA and Combinatorial Molecular Network Annotation Propagation. Journal of Natural Products. PMID 31181921 DOI: 10.1021/acs.jnatprod.8b00916  0.4
2019 Jarmusch AK, Elijah EO, Vargas F, Bouslimani A, da Silva RR, Ernst M, Wang M, Del Rosario KK, Dorrestein PC, Tsunoda SM. Initial Development Towards Non-Invasive Drug Monitoring via Untargeted Mass Spectrometric Analysis of Human Skin. Analytical Chemistry. PMID 31074958 DOI: 10.1021/acs.analchem.8b05854  0.84
2019 Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R. Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems. Msystems. 4. PMID 31058230 DOI: 10.1128/mSystems.00058-19  0.64
2019 Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, et al. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media. Scientific Data. 6: 43. PMID 31028276 DOI: 10.1038/s41597-019-0051-4  0.8
2019 Molina-Santiago C, Pearson JR, Navarro Y, Berlanga-Clavero MV, Caraballo-Rodriguez AM, Petras D, García-Martín ML, Lamon G, Haberstein B, Cazorla FM, de Vicente A, Loquet A, Dorrestein PC, Romero D. The extracellular matrix protects Bacillus subtilis colonies from Pseudomonas invasion and modulates plant co-colonization. Nature Communications. 10: 1919. PMID 31015472 DOI: 10.1038/s41467-019-09944-x  0.84
2019 Aleti G, Baker JL, Tang X, Alvarez R, Dinis M, Tran NC, Melnik AV, Zhong C, Ernst M, Dorrestein PC, Edlund A. Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease. Mbio. 10. PMID 30992349 DOI: 10.1128/mBio.00321-19  0.4
2019 Dührkop K, Fleischauer M, Ludwig M, Aksenov AA, Melnik AV, Meusel M, Dorrestein PC, Rousu J, Böcker S. SIRIUS 4: a rapid tool for turning tandem mass spectra into metabolite structure information. Nature Methods. PMID 30886413 DOI: 10.1038/s41592-019-0344-8  0.4
2019 Li X, Brejnrod AD, Ernst M, Rykær M, Herschend J, Olsen NMC, Dorrestein PC, Rensing C, Sørensen SJ. Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites. Environment International. 126: 454-467. PMID 30844581 DOI: 10.1016/j.envint.2019.02.048  0.4
2019 Kang KB, Ernst M, van der Hooft JJJ, da Silva RR, Park J, Medema MH, Sung SH, Dorrestein PC. Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae. The Plant Journal : For Cell and Molecular Biology. PMID 30786088 DOI: 10.1111/tpj.14292  0.4
2019 Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, ... Dorrestein PC, et al. Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome. Microbiome. 7: 23. PMID 30760325 DOI: 10.1186/s40168-019-0636-3  0.8
2018 Mohimani H, Gurevich A, Shlemov A, Mikheenko A, Korobeynikov A, Cao L, Shcherbin E, Nothias LF, Dorrestein PC, Pevzner PA. Dereplication of microbial metabolites through database search of mass spectra. Nature Communications. 9: 4035. PMID 30279420 DOI: 10.1038/s41467-018-06082-8  0.6
2018 Gonzalez A, Navas-Molina JA, Kosciolek T, McDonald D, Vázquez-Baeza Y, Ackermann G, DeReus J, Janssen S, Swafford AD, Orchanian SB, Sanders JG, Shorenstein J, Holste H, Petrus S, Robbins-Pianka A, ... ... Dorrestein PC, et al. Qiita: rapid, web-enabled microbiome meta-analysis. Nature Methods. 15: 796-798. PMID 30275573 DOI: 10.1038/s41592-018-0141-9  0.4
2018 da Silva RR, Vargas F, Ernst M, Nguyen NH, Bolleddu S, Del Rosario KK, Tsunoda SM, Dorrestein PC, Jarmusch AK. Computational Removal of Undesired Mass Spectral Features Possessing Repeat Units via a Kendrick Mass Filter. Journal of the American Society For Mass Spectrometry. PMID 30267361 DOI: 10.1007/s13361-018-2069-9  0.84
2018 Quinn RA, Comstock W, Zhang T, Morton JT, da Silva R, Tran A, Aksenov A, Nothias LF, Wangpraseurt D, Melnik AV, Ackermann G, Conrad D, Klapper I, Knight R, Dorrestein PC. Niche partitioning of a pathogenic microbiome driven by chemical gradients. Science Advances. 4: eaau1908. PMID 30263961 DOI: 10.1126/sciadv.aau1908  0.4
2018 Kang KB, Park EJ, da Silva RR, Kim HW, Dorrestein PC, Sung SH. Targeted Isolation of Neuroprotective Dicoumaroyl Neolignans and Lignans from Sageretia theezans Using in Silico Molecular Network Annotation Propagation-Based Dereplication. Journal of Natural Products. PMID 30106290 DOI: 10.1021/acs.jnatprod.8b00292  0.4
2018 Tripathi A, Marotz C, Gonzalez A, Vázquez-Baeza Y, Song SJ, Bouslimani A, McDonald D, Zhu Q, Sanders JG, Smarr L, Dorrestein PC, Knight R. Are microbiome studies ready for hypothesis-driven research? Current Opinion in Microbiology. 44: 61-69. PMID 30059804 DOI: 10.1016/j.mib.2018.07.002  0.4
2018 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... ... Dorrestein PC, et al. Author Correction: Inflammation-induced IgA cells dismantle anti-liver cancer immunity. Nature. PMID 29973714 DOI: 10.1038/s41586-018-0304-y  0.72
2018 Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG. Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome. Msystems. 3. PMID 29896566 DOI: 10.1128/mSystems.00020-18  0.64
2018 McDonald D, Hyde E, Debelius JW, Morton JT, Gonzalez A, Ackermann G, Aksenov AA, Behsaz B, Brennan C, Chen Y, DeRight Goldasich L, Dorrestein PC, Dunn RR, Fahimipour AK, Gaffney J, et al. American Gut: an Open Platform for Citizen Science Microbiome Research. Msystems. 3. PMID 29795809 DOI: 10.1128/mSystems.00031-18  0.6
2018 Knight R, Vrbanac A, Taylor BC, Aksenov A, Callewaert C, Debelius J, Gonzalez A, Kosciolek T, McCall LI, McDonald D, Melnik AV, Morton JT, Navas J, Quinn RA, Sanders JG, ... ... Dorrestein PC, et al. Best practices for analysing microbiomes. Nature Reviews. Microbiology. PMID 29795328 DOI: 10.1038/s41579-018-0029-9  0.4
2018 da Silva RR, Wang M, Nothias LF, van der Hooft JJJ, Caraballo-Rodríguez AM, Fox E, Balunas MJ, Klassen JL, Lopes NP, Dorrestein PC. Propagating annotations of molecular networks using in silico fragmentation. Plos Computational Biology. 14: e1006089. PMID 29668671 DOI: 10.1371/journal.pcbi.1006089  0.4
2018 McCall LI, Tripathi A, Vargas F, Knight R, Dorrestein PC, Siqueira-Neto JL. Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome. Plos Neglected Tropical Diseases. 12: e0006344. PMID 29529084 DOI: 10.1371/journal.pntd.0006344  0.4
2018 Nothias LF, Nothias-Esposito M, da Silva R, Wang M, Protsyuk I, Zhang Z, Sarvepalli A, Leyssen P, Touboul D, Costa J, Paolini J, Alexandrov T, Litaudon M, Dorrestein PC. Bioactivity-Based Molecular Networking for the Discovery of Drug Leads in Natural Product Bioassay-Guided Fractionation. Journal of Natural Products. PMID 29498278 DOI: 10.1021/acs.jnatprod.7b00737  0.4
2018 Kapono CA, Morton JT, Bouslimani A, Melnik AV, Orlinsky K, Knaan TL, Garg N, Vázquez-Baeza Y, Protsyuk I, Janssen S, Zhu Q, Alexandrov T, Smarr L, Knight R, Dorrestein PC. Creating a 3D microbial and chemical snapshot of a human habitat. Scientific Reports. 8: 3669. PMID 29487294 DOI: 10.1038/s41598-018-21541-4  0.4
2018 Dorrestein PC, Balskus EP. Chemical signaling at the eukaryotic/prokaryotic interface. Chemical Society Reviews. PMID 29479607 DOI: 10.1039/c8cs90021c  1
2018 Puri AW, Mevers E, Ramadhar TR, Petras D, Liu D, Piel J, Dorrestein PC, Greenberg P, Lidstrom ME, Clardy J. Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism. Journal of the American Chemical Society. PMID 29361220 DOI: 10.1021/jacs.7b12240  0.84
2018 Protsyuk I, Melnik AV, Nothias LF, Rappez L, Phapale P, Aksenov AA, Bouslimani A, Ryazanov S, Dorrestein PC, Alexandrov T. 3D molecular cartography using LC-MS facilitated by Optimus and 'ili software. Nature Protocols. 13: 134-154. PMID 29266099 DOI: 10.1038/nprot.2017.122  0.4
2017 Pla D, Petras D, Saviola AJ, Modahl CM, Sanz L, Pérez A, Juárez E, Frietze S, Dorrestein PC, Mackessy SP, Calvete JJ. Transcriptomics-guided bottom-up and top-down venomics of neonate and adult specimens of the arboreal rear-fanged Brown Treesnake, Boiga irregularis, from Guam. Journal of Proteomics. 174: 71-84. PMID 29292096 DOI: 10.1016/j.jprot.2017.12.020  0.84
2017 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... ... Dorrestein PC, et al. Erratum: Inflammation-induced IgA(+) cells dismantle anti-liver cancer immunity. Nature. PMID 29168501 DOI: 10.1038/nature25028  0.72
2017 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... ... Dorrestein PC, et al. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 551: 340-345. PMID 29144460 DOI: 10.1038/nature24302  0.72
2017 Scheubert K, Hufsky F, Petras D, Wang M, Nothias LF, Dührkop K, Bandeira N, Dorrestein PC, Böcker S. Significance estimation for large scale metabolomics annotations by spectral matching. Nature Communications. 8: 1494. PMID 29133785 DOI: 10.1038/s41467-017-01318-5  0.84
2017 Hartmann AC, Petras D, Quinn RA, Protsyuk I, Archer FI, Ransome E, Williams GJ, Bailey BA, Vermeij MJA, Alexandrov T, Dorrestein PC, Rohwer FL. Meta-mass shift chemical profiling of metabolomes from coral reefs. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078340 DOI: 10.1073/pnas.1710248114  0.84
2017 Garg N, Wang M, Hyde E, da Silva RR, Melnik AV, Protsyuk I, Bouslimani A, Lim YW, Wong R, Humphrey G, Ackermann G, Spivey T, Brouha SS, Bandeira N, Lin GY, ... ... Dorrestein PC, et al. Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung. Cell Host & Microbe. PMID 29056429 DOI: 10.1016/j.chom.2017.10.001  0.64
2017 Vázquez-Baeza Y, Callewaert C, Debelius J, Hyde E, Marotz C, Morton JT, Swafford A, Vrbanac A, Dorrestein PC, Knight R. Impacts of the Human Gut Microbiome on Therapeutics. Annual Review of Pharmacology and Toxicology. PMID 28968189 DOI: 10.1146/annurev-pharmtox-042017-031849  0.32
2017 Ainsworth S, Petras D, Engmark M, Süssmuth RD, Whiteley G, Albulescu LO, Kazandjian TD, Wagstaff SC, Rowley P, Wüster W, Dorrestein PC, Arias AS, Gutiérrez JM, Harrison RA, Casewell NR, et al. The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms. Journal of Proteomics. PMID 28843532 DOI: 10.1016/j.jprot.2017.08.016  0.84
2017 Naman CB, Almaliti J, Armstrong L, Caro-Díaz EJ, Pierce ML, Glukhov E, Fenner A, Spadafora C, Debonsi HM, Dorrestein PC, Murray TF, Gerwick WH. Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species. Journal of Natural Products. PMID 28783331 DOI: 10.1021/acs.jnatprod.7b00367  0.56
2017 Edlund A, Garg N, Mohimani H, Gurevich A, He X, Shi W, Dorrestein PC, McLean JS. Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules. Msystems. 2. PMID 28761934 DOI: 10.1128/mSystems.00058-17  0.6
2017 Hsu CC, Baker MW, Gaasterland T, Meehan MJ, Macagno ER, Dorrestein PC. Top-Down Atmospheric Ionization Mass Spectrometry Microscopy Combined With Proteogenomics. Analytical Chemistry. PMID 28692290 DOI: 10.1021/acs.analchem.7b01096  0.64
2017 Melnik AV, Dorrestein PC, da Silva RR, Hyde ER, Aksenov AA, Vargas F, Bouslimani A, Protsyuk I, Jarmusch A, Tripathi A, Alexandrov T, Knight R. Coupling targeted and untargeted mass spectrometry for metabolome-microbiome-wide association studies of human fecal samples. Analytical Chemistry. PMID 28628333 DOI: 10.1021/acs.analchem.7b01381  0.4
2017 Luzzatto Knaan T, Garg N, Wang M, Glukhov E, Peng Y, Ackermann G, Amir A, Duggan BM, Ryazanov S, Gerwick L, Knight R, Alexandrov T, Bandeira N, Gerwick WH, Dorrestein PC. Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. Elife. 6. PMID 28492366 DOI: 10.7554/eLife.24214  0.64
2017 Kinnel RB, Esquenazi E, Leao T, Moss N, Mevers E, Pereira AR, Monroe EA, Korobeynikov A, Murray TF, Sherman D, Gerwick L, Dorrestein PC, Gerwick WH. A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. Journal of Natural Products. PMID 28448144 DOI: 10.1021/acs.jnatprod.7b00019  0.56
2017 Floros DJ, Petras D, Kapono CA, Melnik AV, Ling TJ, Knight R, Dorrestein PC. Mass Spectrometry Based Molecular 3D-Cartography of Plant Metabolites. Frontiers in Plant Science. 8: 429. PMID 28405197 DOI: 10.3389/fpls.2017.00429  0.84
2017 Crüsemann M, O'Neill EC, Larson CB, Melnik AV, Floros DJ, da Silva RR, Jensen PR, Dorrestein PC, Moore BS. Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols. Journal of Natural Products. 80: 588-597. PMID 28335604 DOI: 10.1021/acs.jnatprod.6b00722  0.64
2017 Nakatsuji T, Chen TH, Narala S, Chun KA, Two AM, Yun T, Shafiq F, Kotol PF, Bouslimani A, Melnik AV, Latif H, Kim JN, Lockhart A, Artis K, David G, ... ... Dorrestein PC, et al. Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis. Science Translational Medicine. 9. PMID 28228596 DOI: 10.1126/scitranslmed.aah4680  0.72
2017 Morton JT, Sanders J, Quinn RA, McDonald D, Gonzalez A, Vázquez-Baeza Y, Navas-Molina JA, Song SJ, Metcalf JL, Hyde ER, Lladser M, Dorrestein PC, Knight R. Balance Trees Reveal Microbial Niche Differentiation. Msystems. 2. PMID 28144630 DOI: 10.1128/mSystems.00162-16  0.4
2017 Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, ... ... Dorrestein PC, et al. Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nature Microbiology. 2: 17010. PMID 28112718 DOI: 10.1038/nmicrobiol.2017.10  0.64
2017 Petras D, Jarmusch AK, Dorrestein PC. From single cells to our planet-recent advances in using mass spectrometry for spatially resolved metabolomics. Current Opinion in Chemical Biology. 36: 24-31. PMID 28086192 DOI: 10.1016/j.cbpa.2016.12.018  0.84
2017 Naman CB, Rattan R, Nikoulina SE, Lee J, Miller BW, Moss NA, Armstrong L, Boudreau PD, Debonsi HM, Valeriote FA, Dorrestein PC, Gerwick WH. Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium. Journal of Natural Products. PMID 28055219 DOI: 10.1021/acs.jnatprod.6b00907  0.56
2016 Garg N, Zeng Y, Edlund A, Melnik AV, Sanchez LM, Mohimani H, Gurevich A, Miao V, Schiffler S, Lim YW, Luzzatto-Knaan T, Cai S, Rohwer F, Pevzner PA, Cichewicz RH, ... ... Dorrestein PC, et al. Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen. Msystems. 1. PMID 28028548 DOI: 10.1128/mSystems.00139-16  0.6
2016 Garg N, Luzzatto-Knaan T, Melnik AV, Caraballo-Rodríguez AM, Floros DJ, Petras D, Gregor R, Dorrestein PC, Phelan VV. Natural products as mediators of disease. Natural Product Reports. PMID 27874907 DOI: 10.1039/c6np00063k  0.84
2016 Bouslimani A, Melnik AV, Xu Z, Amir A, da Silva RR, Wang M, Bandeira N, Alexandrov T, Knight R, Dorrestein PC. Lifestyle chemistries from phones for individual profiling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27849584 DOI: 10.1073/pnas.1610019113  0.64
2016 Quinn RA, Nothias LF, Vining O, Meehan M, Esquenazi E, Dorrestein PC. Molecular Networking As a Drug Discovery, Drug Metabolism, and Precision Medicine Strategy. Trends in Pharmacological Sciences. PMID 27842887 DOI: 10.1016/j.tips.2016.10.011  0.56
2016 Wohlgemuth G, Mehta SS, Mejia RF, Neumann S, Pedrosa D, Pluskal T, Schymanski EL, Willighagen EL, Wilson M, Wishart DS, Arita M, Dorrestein PC, Bandeira N, Wang M, Schulze T, et al. SPLASH, a hashed identifier for mass spectra. Nature Biotechnology. 34: 1099-1101. PMID 27824832 DOI: 10.1038/nbt.3689  0.64
2016 Maansson M, Vynne NG, Klitgaard A, Nybo JL, Melchiorsen J, Nguyen DD, Sanchez LM, Ziemert N, Dorrestein PC, Andersen MR, Gram L. An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria. Msystems. 1. PMID 27822535 DOI: 10.1128/mSystems.00028-15  0.56
2016 Quinn RA, Navas-Molina JA, Hyde ER, Song SJ, Vázquez-Baeza Y, Humphrey G, Gaffney J, Minich JJ, Melnik AV, Herschend J, DeReus J, Durant A, Dutton RJ, Khosroheidari M, Green C, ... ... Dorrestein PC, et al. From Sample to Multi-Omics Conclusions in under 48 Hours. Msystems. 1. PMID 27822524 DOI: 10.1128/mSystems.00038-16  0.4
2016 Mohimani H, Gurevich A, Mikheenko A, Garg N, Nothias LF, Ninomiya A, Takada K, Dorrestein PC, Pevzner PA. Dereplication of peptidic natural products through database search of mass spectra. Nature Chemical Biology. PMID 27820803 DOI: 10.1038/nchembio.2219  0.6
2016 Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, ... ... Dorrestein PC, et al. Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nature Microbiology. 2: 16197. PMID 27798598 DOI: 10.1038/nmicrobiol.2016.197  0.64
2016 Petras D, Nothias LF, Quinn RA, Alexandrov T, Bandeira N, Bouslimani A, Castro-Falcón G, Chen L, Dang T, Floros DJ, Hook VY, Garg N, Hoffner N, Jiang Y, Kapono CA, ... ... Dorrestein PC, et al. Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats. Analytical Chemistry. PMID 27732780 DOI: 10.1021/acs.analchem.6b03456  0.84
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Dorrestein PC, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/nbt.3597  0.96
2016 Gilbert JA, Quinn RA, Debelius J, Xu ZZ, Morton J, Garg N, Jansson JK, Dorrestein PC, Knight R. Microbiome-wide association studies link dynamic microbial consortia to disease. Nature. 535: 94-103. PMID 27383984 DOI: 10.1038/nature18850  1
2016 Miyamoto S, Hsu CC, Hamm G, Darshi M, Diamond-Stanic M, Declèves AE, Slater L, Pennathur S, Stauber J, Dorrestein PC, Sharma K. Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator. Ebiomedicine. 7: 121-134. PMID 27322466 DOI: 10.1016/j.ebiom.2016.03.033  0.4
2016 Deveau A, Gross H, Palin B, Mehnaz S, Schnepf M, Leblond P, Dorrestein PC, Aigle B. Role of secondary metabolites in the interaction between Pseudomonas fluorescens and soil microorganisms under iron limited conditions. Fems Microbiology Ecology. PMID 27199346 DOI: 10.1093/femsec/fiw107  1
2016 Dorrestein PC, Gallo RL, Knight R. Microbial Skin Inhabitants: Friends Forever. Cell. 165: 771-772. PMID 27153488 DOI: 10.1016/j.cell.2016.04.035  1
2016 Quinn RA, Vermeij MJ, Hartmann AC, Galtier d'Auriac I, Benler S, Haas A, Quistad SD, Lim YW, Little M, Sandin S, Smith JE, Dorrestein PC, Rohwer F. Metabolomics of reef benthic interactions reveals a bioactive lipid involved in coral defence. Proceedings. Biological Sciences / the Royal Society. 283. PMID 27122568 DOI: 10.1098/rspb.2016.0469  1
2016 Moran MA, Kujawinski EB, Stubbins A, Fatland R, Aluwihare LI, Buchan A, Crump BC, Dorrestein PC, Dyhrman ST, Hess NJ, Howe B, Longnecker K, Medeiros PM, Niggemann J, Obernosterer I, et al. Deciphering ocean carbon in a changing world. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951682 DOI: 10.1073/pnas.1514645113  1
2016 Spraker JE, Sanchez LM, Lowe TM, Dorrestein PC, Keller NP. Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues. The Isme Journal. PMID 26943626 DOI: 10.1038/ismej.2016.32  0.56
2015 Nonejuie P, Trial RM, Newton GL, Lamsa A, Ranmali Perera V, Aguilar J, Liu WT, Dorrestein PC, Pogliano J, Pogliano K. Application of bacterial cytological profiling to crude natural product extracts reveals the antibacterial arsenal of Bacillus subtilis. The Journal of Antibiotics. PMID 26648120 DOI: 10.1038/ja.2015.116  1
2015 Quinn RA, Phelan VV, Whiteson KL, Garg N, Bailey BA, Lim YW, Conrad DJ, Dorrestein PC, Rohwer FL. Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome. The Isme Journal. PMID 26623545 DOI: 10.1038/ismej.2015.207  1
2015 de Bruijn I, Cheng X, de Jager V, Expósito RG, Watrous J, Patel N, Postma J, Dorrestein PC, Kobayashi D, Raaijmakers JM. Comparative genomics and metabolic profiling of the genus Lysobacter. Bmc Genomics. 16: 991. PMID 26597042 DOI: 10.1186/s12864-015-2191-z  1
2015 Alivisatos AP, Blaser MJ, Brodie EL, Chun M, Dangl JL, Donohue TJ, Dorrestein PC, Gilbert JA, Green JL, Jansson JK, Knight R, Maxon ME, McFall-Ngai MJ, Miller JF, Pollard KS, et al. MICROBIOME. A unified initiative to harness Earth's microbiomes. Science (New York, N.Y.). 350: 507-8. PMID 26511287 DOI: 10.1126/science.aac8480  1
2015 da Silva RR, Dorrestein PC, Quinn RA. Illuminating the dark matter in metabolomics. Proceedings of the National Academy of Sciences of the United States of America. 112: 12549-50. PMID 26430243 DOI: 10.1073/pnas.1516878112  1
2015 Agarwal V, Diethelm S, Ray L, Garg N, Awakawa T, Dorrestein PC, Moore BS. Chemoenzymatic Synthesis of Acyl Coenzyme A Substrates Enables in Situ Labeling of Small Molecules and Proteins. Organic Letters. 17: 4452-5. PMID 26333306 DOI: 10.1021/acs.orglett.5b02113  1
2015 Liu Y, Rzeszutek E, van der Voort M, Wu CH, Thoen E, Skaar I, Bulone V, Dorrestein PC, Raaijmakers JM, de Bruijn I. Diversity of Aquatic Pseudomonas Species and Their Activity against the Fish Pathogenic Oomycete Saprolegnia. Plos One. 10: e0136241. PMID 26317985 DOI: 10.1371/journal.pone.0136241  1
2015 Hoffmann T, Dorrestein PC. Homogeneous Matrix Deposition on Dried Agar for MALDI Imaging Mass Spectrometry of Microbial Cultures. Journal of the American Society For Mass Spectrometry. 26: 1959-62. PMID 26297185 DOI: 10.1007/s13361-015-1241-8  1
2015 Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Dorrestein PC, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/nchembio.1890  1
2015 Rateb ME, Zhai Y, Ehrner E, Rath CM, Wang X, Tabudravu J, Ebel R, Bibb M, Kyeremeh K, Dorrestein PC, Hong K, Jaspars M, Deng H. Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate. Organic & Biomolecular Chemistry. 13: 9585-92. PMID 26256511 DOI: 10.1039/c5ob01269d  1
2015 Patin NV, Duncan KR, Dorrestein PC, Jensen PR. Competitive strategies differentiate closely related species of marine actinobacteria. The Isme Journal. PMID 26241505 DOI: 10.1038/ismej.2015.128  1
2015 Liaw CC, Chen PC, Shih CJ, Tseng SP, Lai YM, Hsu CH, Dorrestein PC, Yang YL. Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach. Scientific Reports. 5: 12856. PMID 26238555 DOI: 10.1038/srep12856  0.64
2015 Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH. Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows. Plos One. 10: e0133297. PMID 26222584 DOI: 10.1371/journal.pone.0133297  1
2015 Van Der Voort M, Meijer HJ, Schmidt Y, Watrous J, Dekkers E, Mendes R, Dorrestein PC, Gross H, Raaijmakers JM. Genome mining and metabolic profiling of the rhizosphere bacterium Pseudomonas sp. SH-C52 for antimicrobial compounds. Frontiers in Microbiology. 6: 693. PMID 26217324 DOI: 10.3389/fmicb.2015.00693  1
2015 Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. Journal of Natural Products. PMID 26149623 DOI: 10.1021/acs.jnatprod.5b00301  1
2015 Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W. Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation. Proceedings of the National Academy of Sciences of the United States of America. 112: E3327-36. PMID 26080448 DOI: 10.1073/pnas.1509658112  1
2015 Teufel R, Stull F, Meehan MJ, Michaudel Q, Dorrestein PC, Palfey B, Moore BS. Biochemical Establishment and Characterization of EncM's Flavin-N5-oxide Cofactor. Journal of the American Chemical Society. 137: 8078-85. PMID 26067765 DOI: 10.1021/jacs.5b03983  1
2015 Edlund A, Yang Y, Yooseph S, Hall AP, Nguyen DD, Dorrestein PC, Nelson KE, He X, Lux R, Shi W, McLean JS. Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism. The Isme Journal. PMID 26023872 DOI: 10.1038/ismej.2015.72  1
2015 Song J, Liu X, Rao TS, Chang L, Meehan MJ, Blevitt JM, Wu J, Dorrestein PC, Milla ME. Phenotyping Drug Polypharmacology via Eicosanoid Profiling of Blood. Journal of Lipid Research. PMID 26022804 DOI: 10.1194/jlr.M058677  1
2015 Luzzatto-Knaan T, Melnik AV, Dorrestein PC. Mass spectrometry tools and workflows for revealing microbial chemistry. The Analyst. PMID 25996313 DOI: 10.1039/c5an00171d  1
2015 Briand E, Bormans M, Gugger M, Dorrestein PC, Gerwick WH. Changes in secondary metabolic profiles of Microcystis aeruginosa strains in response to intraspecific interactions. Environmental Microbiology. PMID 25980449 DOI: 10.1111/1462-2920.12904  1
2015 Oetjen J, Veselkov K, Watrous J, McKenzie JS, Becker M, Hauberg-Lotte L, Kobarg JH, Strittmatter N, Mróz AK, Hoffmann F, Trede D, Palmer A, Schiffler S, Steinhorst K, Aichler M, ... ... Dorrestein PC, et al. Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry. Gigascience. 4: 20. PMID 25941567 DOI: 10.1186/s13742-015-0059-4  0.4
2015 Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR. Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species. Chemistry & Biology. 22: 460-71. PMID 25865308 DOI: 10.1016/j.chembiol.2015.03.010  1
2015 Garg N, Kapono C, Lim YW, Koyama N, Vermeij MJ, Conrad D, Rohwer F, Dorrestein PC. Mass spectral similarity for untargeted metabolomics data analysis of complex mixtures. International Journal of Mass Spectrometry. 377: 719-717. PMID 25844058 DOI: 10.1016/j.ijms.2014.06.005  1
2015 Bouslimani A, Porto C, Rath CM, Wang M, Guo Y, Gonzalez A, Berg-Lyon D, Ackermann G, Moeller Christensen GJ, Nakatsuji T, Zhang L, Borkowski AW, Meehan MJ, Dorrestein K, Gallo RL, ... ... Dorrestein PC, et al. Molecular cartography of the human skin surface in 3D. Proceedings of the National Academy of Sciences of the United States of America. 112: E2120-9. PMID 25825778 DOI: 10.1073/pnas.1424409112  1
2015 Phelan VV, Fang J, Dorrestein PC. Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin. Journal of the American Society For Mass Spectrometry. 26: 873-7. PMID 25801585 DOI: 10.1007/s13361-015-1101-6  1
2015 Michelsen CF, Watrous J, Glaring MA, Kersten R, Koyama N, Dorrestein PC, Stougaard P. Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil. Mbio. 6: e00079. PMID 25784695 DOI: 10.1128/mBio.00079-15  1
2015 Mascuch SJ, Moree WJ, Hsu CC, Turner GG, Cheng TL, Blehert DS, Kilpatrick AM, Frick WF, Meehan MJ, Dorrestein PC, Gerwick L. Direct detection of fungal siderophores on bats with white-nose syndrome via fluorescence microscopy-guided ambient ionization mass spectrometry. Plos One. 10: e0119668. PMID 25781976 DOI: 10.1371/journal.pone.0119668  1
2015 Lu L, Meehan MJ, Gu S, Chen Z, Zhang W, Zhang G, Liu L, Huang X, Dorrestein PC, Xu Y, Moore BS, Qian PY. Mechanism of action of thalassospiramides, a new class of calpain inhibitors. Scientific Reports. 5: 8783. PMID 25740631 DOI: 10.1038/srep08783  1
2015 Bleich R, Watrous JD, Dorrestein PC, Bowers AA, Shank EA. Thiopeptide antibiotics stimulate biofilm formation in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 112: 3086-91. PMID 25713360 DOI: 10.1073/pnas.1414272112  1
2015 Bertin MJ, Schwartz SL, Lee J, Korobeynikov A, Dorrestein PC, Gerwick L, Gerwick WH. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. Journal of Natural Products. 78: 493-9. PMID 25668560 DOI: 10.1021/np5009762  1
2015 He X, McLean JS, Edlund A, Yooseph S, Hall AP, Liu SY, Dorrestein PC, Esquenazi E, Hunter RC, Cheng G, Nelson KE, Lux R, Shi W. Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle. Proceedings of the National Academy of Sciences of the United States of America. 112: 244-9. PMID 25535390 DOI: 10.1073/pnas.1419038112  1
2015 Hsu CC, Dorrestein PC. Visualizing life with ambient mass spectrometry. Current Opinion in Biotechnology. 31: 24-34. PMID 25146170 DOI: 10.1016/j.copbio.2014.07.005  1
2015 Ross AC, Gulland LE, Dorrestein PC, Moore BS. Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform. Acs Synthetic Biology. 4: 414-20. PMID 25140825 DOI: 10.1021/sb500280q  1
2015 Liaw CC, Chen PC, Shih CJ, Tseng SP, Lai YM, Hsu CH, Dorrestein PC, Yang YL. Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach Scientific Reports. 5. DOI: 10.1038/srep12856  1
2015 Song C, Mazzola M, Cheng X, Oetjen J, Alexandrov T, Dorrestein P, Watrous J, Van Der Voort M, Raaijmakers JM. Molecular and chemical dialogues in bacteria-protozoa interactions Scientific Reports. 5. DOI: 10.1038/srep12837  1
2015 Brito Â, Gaifem J, Ramos V, Glukhov E, Dorrestein PC, Gerwick WH, Vasconcelos VM, Mendes MV, Tamagnini P. Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity Algal Research. 9: 218-226. DOI: 10.1016/j.algal.2015.03.016  1
2014 Gonzalez DJ, Corriden R, Akong-Moore K, Olson J, Dorrestein PC, Nizet V. N-terminal ArgD peptides from the classical Staphylococcus aureus Agr system have cytotoxic and proinflammatory activities. Chemistry & Biology. 21: 1457-62. PMID 25457179 DOI: 10.1016/j.chembiol.2014.09.015  1
2014 Sharon G, Garg N, Debelius J, Knight R, Dorrestein PC, Mazmanian SK. Specialized metabolites from the microbiome in health and disease. Cell Metabolism. 20: 719-30. PMID 25440054 DOI: 10.1016/j.cmet.2014.10.016  1
2014 Medema MH, Paalvast Y, Nguyen DD, Melnik A, Dorrestein PC, Takano E, Breitling R. Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products. Plos Computational Biology. 10: e1003822. PMID 25188327 DOI: 10.1371/journal.pcbi.1003822  1
2014 Mohimani H, Liu WT, Kersten RD, Moore BS, Dorrestein PC, Pevzner PA. NRPquest: Coupling Mass Spectrometry and Genome Mining for Nonribosomal Peptide Discovery. Journal of Natural Products. PMID 25116163 DOI: 10.1021/np500370c  1
2014 Fang J, Dorrestein PC. Emerging mass spectrometry techniques for the direct analysis of microbial colonies. Current Opinion in Microbiology. 19: 120-9. PMID 25064218 DOI: 10.1016/j.mib.2014.06.014  1
2014 Moree WJ, McConnell OJ, Nguyen DD, Sanchez LM, Yang YL, Zhao X, Liu WT, Boudreau PD, Srinivasan J, Atencio L, Ballesteros J, Gavilán RG, Torres-Mendoza D, Guzmán HM, Gerwick WH, ... ... Dorrestein PC, et al. Microbiota of healthy corals are active against fungi in a light-dependent manner. Acs Chemical Biology. 9: 2300-8. PMID 25058318 DOI: 10.1021/cb500432j  1
2014 Dorrestein PC, Mazmanian SK, Knight R. Finding the missing links among metabolites, microbes, and the host. Immunity. 40: 824-32. PMID 24950202 DOI: 10.1016/j.immuni.2014.05.015  1
2014 Mohimani H, Kersten RD, Liu WT, Wang M, Purvine SO, Wu S, Brewer HM, Pasa-Tolic L, Bandeira N, Moore BS, Pevzner PA, Dorrestein PC. Automated genome mining of ribosomal peptide natural products. Acs Chemical Biology. 9: 1545-51. PMID 24802639 DOI: 10.1021/cb500199h  1
2014 Dorrestein PC. Editorial: Mass spectrometry of small molecules and natural products. Natural Product Reports. 31: 704-5. PMID 24801653 DOI: 10.1039/c4np90016b  1
2014 Bouslimani A, Sanchez LM, Garg N, Dorrestein PC. Mass spectrometry of natural products: current, emerging and future technologies. Natural Product Reports. 31: 718-29. PMID 24801551 DOI: 10.1039/c4np00044g  1
2014 Ursell LK, Haiser HJ, Van Treuren W, Garg N, Reddivari L, Vanamala J, Dorrestein PC, Turnbaugh PJ, Knight R. The intestinal metabolome: an intersection between microbiota and host. Gastroenterology. 146: 1470-6. PMID 24631493 DOI: 10.1053/j.gastro.2014.03.001  1
2014 Mevers E, Haeckl FP, Boudreau PD, Byrum T, Dorrestein PC, Valeriote FA, Gerwick WH. Lipopeptides from the tropical marine cyanobacterium Symploca sp. Journal of Natural Products. 77: 969-75. PMID 24588245 DOI: 10.1021/np401051z  1
2014 Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Molecular & Cellular Proteomics : McP. 13: 1262-72. PMID 24567418 DOI: 10.1074/mcp.M113.031336  1
2014 Phelan VV, Moree WJ, Aguilar J, Cornett DS, Koumoutsi A, Noble SM, Pogliano K, Guerrero CA, Dorrestein PC. Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa. Journal of Bacteriology. 196: 1683-93. PMID 24532776 DOI: 10.1128/JB.01258-13  1
2014 Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111: 1957-62. PMID 24449899 DOI: 10.1073/pnas.1319584111  1
2014 Winnikoff JR, Glukhov E, Watrous J, Dorrestein PC, Gerwick WH. Quantitative molecular networking to profile marine cyanobacterial metabolomes. The Journal of Antibiotics. 67: 105-12. PMID 24281659 DOI: 10.1038/ja.2013.120  1
2014 Schorn M, Zettler J, Noel JP, Dorrestein PC, Moore BS, Kaysser L. Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors. Acs Chemical Biology. 9: 301-9. PMID 24168704 DOI: 10.1021/cb400699p  1
2014 Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. The Journal of Antibiotics. 67: 99-104. PMID 24149839 DOI: 10.1038/ja.2013.99  1
2013 Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: E4407-16. PMID 24191063 DOI: 10.1073/pnas.1315492110  1
2013 Watrous J, Roach P, Heath B, Alexandrov T, Laskin J, Dorrestein PC. Metabolic profiling directly from the Petri dish using nanospray desorption electrospray ionization imaging mass spectrometry. Analytical Chemistry. 85: 10385-91. PMID 24047514 DOI: 10.1021/ac4023154  1
2013 Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, ... Dorrestein PC, et al. Molecular networking as a dereplication strategy. Journal of Natural Products. 76: 1686-99. PMID 24025162 DOI: 10.1021/np400413s  1
2013 Davis J, Fricke WF, Hamann MT, Esquenazi E, Dorrestein PC, Hill RT. Characterization of the bacterial community of the chemically defended Hawaiian sacoglossan Elysia rufescens. Applied and Environmental Microbiology. 79: 7073-81. PMID 24014539 DOI: 10.1128/AEM.01568-13  1
2013 Soriano EV, Zhang Y, Colabroy KL, Sanders JM, Settembre EC, Dorrestein PC, Begley TP, Ealick SE. Active-site models for complexes of quinolinate synthase with substrates and intermediates. Acta Crystallographica. Section D, Biological Crystallography. 69: 1685-96. PMID 23999292 DOI: 10.1107/S090744491301247X  1
2013 Hsu CC, White NM, Hayashi M, Lin EC, Poon T, Banerjee I, Chen J, Pfaff SL, Macagno ER, Dorrestein PC. Microscopy ambient ionization top-down mass spectrometry reveals developmental patterning. Proceedings of the National Academy of Sciences of the United States of America. 110: 14855-60. PMID 23969833 DOI: 10.1073/pnas.1310618110  1
2013 Traxler MF, Watrous JD, Alexandrov T, Dorrestein PC, Kolter R. Interspecies interactions stimulate diversification of the Streptomyces coelicolor secreted metabolome. Mbio. 4. PMID 23963177 DOI: 10.1128/mBio.00459-13  1
2013 Moree WJ, Yang JY, Zhao X, Liu WT, Aparicio M, Atencio L, Ballesteros J, Sánchez J, Gavilán RG, Gutiérrez M, Dorrestein PC. Imaging mass spectrometry of a coral microbe interaction with fungi. Journal of Chemical Ecology. 39: 1045-54. PMID 23881443 DOI: 10.1007/s10886-013-0320-1  1
2013 Hsu CC, ElNaggar MS, Peng Y, Fang J, Sanchez LM, Mascuch SJ, Møller KA, Alazzeh EK, Pikula J, Quinn RA, Zeng Y, Wolfe BE, Dutton RJ, Gerwick L, Zhang L, ... ... Dorrestein PC, et al. Real-time metabolomics on living microorganisms using ambient electrospray ionization flow-probe. Analytical Chemistry. 85: 7014-8. PMID 23819546 DOI: 10.1021/ac401613x  1
2013 Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, ... ... Dorrestein PC, et al. MS/MS networking guided analysis of molecule and gene cluster families. Proceedings of the National Academy of Sciences of the United States of America. 110: E2611-20. PMID 23798442 DOI: 10.1073/pnas.1303471110  1
2013 Pérez Morales TG, Ho TD, Liu WT, Dorrestein PC, Ellermeier CD. Production of the cannibalism toxin SDP is a multistep process that requires SdpA and SdpB. Journal of Bacteriology. 195: 3244-51. PMID 23687264 DOI: 10.1128/JB.00407-13  1
2013 Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS. Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica. Chembiochem : a European Journal of Chemical Biology. 14: 955-62. PMID 23649992 DOI: 10.1002/cbic.201300147  1
2013 Rath CM, Yang JY, Alexandrov T, Dorrestein PC. Data-independent microbial metabolomics with ambient ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 24: 1167-76. PMID 23568029 DOI: 10.1007/s13361-013-0608-y  1
2013 Sanchez LM, Dorrestein PC. Analytical chemistry: Virulence caught green-handed. Nature Chemistry. 5: 155-7. PMID 23422554 DOI: 10.1038/nchem.1583  1
2013 van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development. The Journal of Biological Chemistry. 288: 6417-26. PMID 23322784 DOI: 10.1074/jbc.M112.448738  1
2013 Watrous JD, Phelan VV, Hsu CC, Moree WJ, Duggan BM, Alexandrov T, Dorrestein PC. Microbial metabolic exchange in 3D. The Isme Journal. 7: 770-80. PMID 23283018 DOI: 10.1038/ismej.2012.155  1
2013 Ross AC, Xu Y, Lu L, Kersten RD, Shao Z, Al-Suwailem AM, Dorrestein PC, Qian PY, Moore BS. Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria. Journal of the American Chemical Society. 135: 1155-62. PMID 23270364 DOI: 10.1021/ja3119674  1
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... Dorrestein PC, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/c2np20085f  1
2013 Song J, Liu X, Wu J, Meehan MJ, Blevitt JM, Dorrestein PC, Milla ME. A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood. Analytical Biochemistry. 433: 181-8. PMID 23103340 DOI: 10.1016/j.ab.2012.10.022  1
2013 Lohr F, Jenniches I, Frizler M, Meehan MJ, Sylvester M, Schmitz A, Gütschow M, Dorrestein PC, König GM, Schäberle TF. α,β → β,γ double bond migration in corallopyronin A biosynthesis Chemical Science. 4: 4175-4180. DOI: 10.1039/c3sc51854j  1
2012 Young TS, Dorrestein PC, Walsh CT. Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants. Chemistry & Biology. 19: 1600-10. PMID 23261603 DOI: 10.1016/j.chembiol.2012.10.013  1
2012 Hollands A, Gonzalez D, Leire E, Donald C, Gallo RL, Sanderson-Smith M, Dorrestein PC, Nizet V. A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides. The Journal of Biological Chemistry. 287: 40891-7. PMID 23038245 DOI: 10.1074/jbc.M112.404582  1
2012 Rath CM, Alexandrov T, Higginbottom SK, Song J, Milla ME, Fischbach MA, Sonnenburg JL, Dorrestein PC. Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations. Analytical Chemistry. 84: 9259-67. PMID 23009651 DOI: 10.1021/ac302039u  1
2012 Boudreau PD, Byrum T, Liu WT, Dorrestein PC, Gerwick WH. Viequeamide A, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium. Journal of Natural Products. 75: 1560-70. PMID 22924493 DOI: 10.1021/np300321b  1
2012 Moree WJ, Phelan VV, Wu CH, Bandeira N, Cornett DS, Duggan BM, Dorrestein PC. Interkingdom metabolic transformations captured by microbial imaging mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 109: 13811-6. PMID 22869730 DOI: 10.1073/pnas.1206855109  1
2012 Hoefler BC, Gorzelnik KV, Yang JY, Hendricks N, Dorrestein PC, Straight PD. Enzymatic resistance to the lipopeptide surfactin as identified through imaging mass spectrometry of bacterial competition. Proceedings of the National Academy of Sciences of the United States of America. 109: 13082-7. PMID 22826229 DOI: 10.1073/pnas.1205586109  1
2012 Yang JY, Phelan VV, Simkovsky R, Watrous JD, Trial RM, Fleming TC, Wenter R, Moore BS, Golden SS, Pogliano K, Dorrestein PC. Primer on agar-based microbial imaging mass spectrometry. Journal of Bacteriology. 194: 6023-8. PMID 22821974 DOI: 10.1128/JB.00823-12  1
2012 Roberts AA, Schultz AW, Kersten RD, Dorrestein PC, Moore BS. Iron acquisition in the marine actinomycete genus Salinispora is controlled by the desferrioxamine family of siderophores. Fems Microbiology Letters. 335: 95-103. PMID 22812504 DOI: 10.1111/j.1574-6968.2012.02641.x  1
2012 Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, ... Dorrestein PC, et al. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. Journal of Proteomics. 75: 5069-76. PMID 22641157 DOI: 10.1016/j.jprot.2012.05.036  1
2012 Guthals A, Watrous JD, Dorrestein PC, Bandeira N. The spectral networks paradigm in high throughput mass spectrometry. Molecular Biosystems. 8: 2535-44. PMID 22610447 DOI: 10.1039/c2mb25085c  1
2012 Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. Mass spectral molecular networking of living microbial colonies. Proceedings of the National Academy of Sciences of the United States of America. 109: E1743-52. PMID 22586093 DOI: 10.1073/pnas.1203689109  1
2012 Lamsa A, Liu WT, Dorrestein PC, Pogliano K. The Bacillus subtilis cannibalism toxin SDP collapses the proton motive force and induces autolysis. Molecular Microbiology. 84: 486-500. PMID 22469514 DOI: 10.1111/j.1365-2958.2012.08038.x  1
2012 Xu Y, Kersten RD, Nam SJ, Lu L, Al-Suwailem AM, Zheng H, Fenical W, Dorrestein PC, Moore BS, Qian PY. Bacterial biosynthesis and maturation of the didemnin anti-cancer agents. Journal of the American Chemical Society. 134: 8625-32. PMID 22458477 DOI: 10.1021/ja301735a  1
2012 Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. The Journal of Biological Chemistry. 287: 13889-98. PMID 22371493 DOI: 10.1074/jbc.M112.349860  1
2012 Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Current Opinion in Microbiology. 15: 147-54. PMID 22209085 DOI: 10.1016/j.mib.2011.12.009  1
2012 Phelan VV, Liu WT, Pogliano K, Dorrestein PC. Microbial metabolic exchange--the chemotype-to-phenotype link. Nature Chemical Biology. 8: 26-35. PMID 22173357 DOI: 10.1038/nchembio.739  1
2011 Yang L, Lin C, Liu W, Zhang J, Ohgi KA, Grinstein JD, Dorrestein PC, Rosenfeld MG. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell. 147: 773-88. PMID 22078878 DOI: 10.1016/j.cell.2011.08.054  1
2011 Mohimani H, Liu WT, Yang YL, Gaudêncio SP, Fenical W, Dorrestein PC, Pevzner PA. Multiplex de novo sequencing of peptide antibiotics. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 1371-81. PMID 22035290 DOI: 10.1089/cmb.2011.0158  1
2011 Chatterjee A, Abeydeera ND, Bale S, Pai PJ, Dorrestein PC, Russell DH, Ealick SE, Begley TP. Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase. Nature. 478: 542-6. PMID 22031445 DOI: 10.1038/nature10503  1
2011 Liu WT, Kersten RD, Yang YL, Moore BS, Dorrestein PC. Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus. Journal of the American Chemical Society. 133: 18010-3. PMID 21999343 DOI: 10.1021/ja2040877  1
2011 Kersten RD, Yang YL, Xu Y, Cimermancic P, Nam SJ, Fenical W, Fischbach MA, Moore BS, Dorrestein PC. A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nature Chemical Biology. 7: 794-802. PMID 21983601 DOI: 10.1038/nchembio.684  1
2011 Szu PH, Govindarajan S, Meehan MJ, Das A, Nguyen DD, Dorrestein PC, Minshull J, Khosla C. Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase. Chemistry & Biology. 18: 1021-31. PMID 21867917 DOI: 10.1016/j.chembiol.2011.07.015  1
2011 Mohimani H, Liu WT, Mylne JS, Poth AG, Colgrave ML, Tran D, Selsted ME, Dorrestein PC, Pevzner PA. Cycloquest: identification of cyclopeptides via database search of their mass spectra against genome databases. Journal of Proteome Research. 10: 4505-12. PMID 21851130 DOI: 10.1021/pr200323a  1
2011 Watrous JD, Dorrestein PC. Imaging mass spectrometry in microbiology. Nature Reviews. Microbiology. 9: 683-94. PMID 21822293 DOI: 10.1038/nrmicro2634  1
2011 Esquenazi E, Daly M, Bahrainwala T, Gerwick WH, Dorrestein PC. Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation. Bioorganic & Medicinal Chemistry. 19: 6639-44. PMID 21784647 DOI: 10.1016/j.bmc.2011.06.081  1
2011 Engene N, Choi H, Esquenazi E, Byrum T, Villa FA, Cao Z, Murray TF, Dorrestein PC, Gerwick L, Gerwick WH. Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera. Journal of Natural Products. 74: 1737-43. PMID 21751786 DOI: 10.1021/np200236c  1
2011 Mohimani H, Yang YL, Liu WT, Hsieh PW, Dorrestein PC, Pevzner PA. Sequencing cyclic peptides by multistage mass spectrometry. Proteomics. 11: 3642-50. PMID 21751357 DOI: 10.1002/pmic.201000697  1
2011 Jones CS, Esquenazi E, Dorrestein PC, Gerwick WH. Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry. Bioorganic & Medicinal Chemistry. 19: 6620-7. PMID 21742508 DOI: 10.1016/j.bmc.2011.06.005  1
2011 Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology (Reading, England). 157: 2485-92. PMID 21719540 DOI: 10.1099/mic.0.048736-0  1
2011 Yang YL, Xu Y, Kersten RD, Liu WT, Meehan MJ, Moore BS, Bandeira N, Dorrestein PC. Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry. Angewandte Chemie (International Ed. in English). 50: 5839-42. PMID 21574228 DOI: 10.1002/anie.201101225  1
2011 Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, ... Dorrestein PC, et al. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America. 108: 8815-20. PMID 21555588 DOI: 10.1073/pnas.1101137108  1
2011 Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH. Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage. Plos One. 6: e18565. PMID 21533272 DOI: 10.1371/journal.pone.0018565  1
2011 Kalaitzis JA, Cheng Q, Meluzzi D, Xiang L, Izumikawa M, Dorrestein PC, Moore BS. Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL. Bioorganic & Medicinal Chemistry. 19: 6633-8. PMID 21531566 DOI: 10.1016/j.bmc.2011.04.024  1
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, ... ... Dorrestein PC, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/AEM.00038-11  1
2011 Mevers E, Liu WT, Engene N, Mohimani H, Byrum T, Pevzner PA, Dorrestein PC, Spadafora C, Gerwick WH. Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera. Journal of Natural Products. 74: 928-36. PMID 21488639 DOI: 10.1021/np200077f  1
2011 Engene N, Choi H, Esquenazi E, Rottacker EC, Ellisman MH, Dorrestein PC, Gerwick WH. Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya. Environmental Microbiology. 13: 1601-10. PMID 21477107 DOI: 10.1111/j.1462-2920.2011.02472.x  1
2011 Esquenazi E, Jones AC, Byrum T, Dorrestein PC, Gerwick WH. Temporal dynamics of natural product biosynthesis in marine cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 108: 5226-31. PMID 21393570 DOI: 10.1073/pnas.1012813108  1
2011 Bruand J, Sistla S, Mériaux C, Dorrestein PC, Gaasterland T, Ghassemian M, Wisztorski M, Fournier I, Salzet M, Macagno E, Bafna V. Automated querying and identification of novel peptides using MALDI mass spectrometric imaging. Journal of Proteome Research. 10: 1915-28. PMID 21332220 DOI: 10.1021/pr101159e  1
2011 Watrous JD, Alexandrov T, Dorrestein PC. The evolving field of imaging mass spectrometry and its impact on future biological research. Journal of Mass Spectrometry : Jms. 46: 209-22. PMID 21322093 DOI: 10.1002/jms.1876  1
2011 Dorrestein PC, Carroll KS. 'Omics' of natural products and redox biology. Current Opinion in Chemical Biology. 15: 3-4. PMID 21282071 DOI: 10.1016/j.cbpa.2011.01.009  1
2011 Yang JY, Karr JR, Watrous JD, Dorrestein PC. Integrating '-omics' and natural product discovery platforms to investigate metabolic exchange in microbiomes. Current Opinion in Chemical Biology. 15: 79-87. PMID 21087892 DOI: 10.1016/j.cbpa.2010.10.025  1
2011 Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. Biochemistry. 50: 287-99. PMID 21069965 DOI: 10.1021/bi1014776  1
2011 Meier JL, Patel AD, Niessen S, Meehan M, Kersten R, Yang JY, Rothmann M, Cravatt BF, Dorrestein PC, Burkart MD, Bafna V. Practical 4'-phosphopantetheine active site discovery from proteomic samples. Journal of Proteome Research. 10: 320-9. PMID 21067235 DOI: 10.1021/pr100953b  1
2010 Garcia BA, Cooper HJ, Dorrestein PC, Tang K, Ueberheide BM. Proteomics. Journal of Biomedicine & Biotechnology. 2010: 453045. PMID 21541239 DOI: 10.1155/2010/453045  1
2010 Liu X, Inbar Y, Dorrestein PC, Wynne C, Edwards N, Souda P, Whitelegge JP, Bafna V, Pevzner PA. Deconvolution and database search of complex tandem mass spectra of intact proteins: a combinatorial approach. Molecular & Cellular Proteomics : McP. 9: 2772-82. PMID 20855543 DOI: 10.1074/mcp.M110.002766  1
2010 Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 107: 16286-90. PMID 20805502 DOI: 10.1073/pnas.1008368107  1
2010 Kersten RD, Dorrestein PC. Metalloenzymes: Natural product nitrosation. Nature Chemical Biology. 6: 636-7. PMID 20720546 DOI: 10.1038/nchembio.425  1
2010 O'Hayre M, Salanga CL, Kipps TJ, Messmer D, Dorrestein PC, Handel TM. Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis. Plos One. 5: e11716. PMID 20661426 DOI: 10.1371/journal.pone.0011716  1
2010 Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 466: 508-12. PMID 20622854 DOI: 10.1038/nature09272  1
2010 Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/jbc.M110.118554  0.36
2010 Leão PN, Pereira AR, Liu WT, Ng J, Pevzner PA, Dorrestein PC, König GM, Vasconcelos VM, Gerwick WH. Synergistic allelochemicals from a freshwater cyanobacterium. Proceedings of the National Academy of Sciences of the United States of America. 107: 11183-8. PMID 20534563 DOI: 10.1073/pnas.0914343107  1
2010 He C, Nora GP, Schneider EL, Kerr ID, Hansell E, Hirata K, Gonzalez D, Sajid M, Boyd SE, Hruz P, Cobo ER, Le C, Liu WT, Eckmann L, Dorrestein PC, et al. A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. The Journal of Biological Chemistry. 285: 18516-27. PMID 20378535 DOI: 10.1074/jbc.M109.086181  1
2010 Zhou H, Qiao K, Gao Z, Meehan MJ, Li JW, Zhao X, Dorrestein PC, Vederas JC, Tang Y. Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis. Journal of the American Chemical Society. 132: 4530-1. PMID 20222707 DOI: 10.1021/ja100060k  1
2010 Watrous J, Hendricks N, Meehan M, Dorrestein PC. Capturing bacterial metabolic exchange using thin film desorption electrospray ionization-imaging mass spectrometry. Analytical Chemistry. 82: 1598-600. PMID 20121185 DOI: 10.1021/ac9027388  1
2010 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE, Bark S, Dorrestein PC. Expansion of the mycobacterial "PUPylome". Molecular Biosystems. 6: 376-85. PMID 20094657 DOI: 10.1039/b916104j  1
2010 Taniguchi M, Nunnery JK, Engene N, Esquenazi E, Byrum T, Dorrestein PC, Gerwick WH. Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 73: 393-8. PMID 19839606 DOI: 10.1021/np900428h  1
2010 Kersten RD, Meehan MJ, Dorrestein PC. Applications of modern mass spectrometry techniques in natural products chemistry Comprehensive Natural Products Ii: Chemistry and Biology. 9: 389-456.  1
2009 Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. Bmc Microbiology. 9: 247. PMID 19951434 DOI: 10.1186/1471-2180-9-247  1
2009 Esquenazi E, Yang YL, Watrous J, Gerwick WH, Dorrestein PC. Imaging mass spectrometry of natural products. Natural Product Reports. 26: 1521-34. PMID 19936384 DOI: 10.1039/b915674g  1
2009 Yang YL, Xu Y, Straight P, Dorrestein PC. Translating metabolic exchange with imaging mass spectrometry. Nature Chemical Biology. 5: 885-7. PMID 19915536 DOI: 10.1038/nchembio.252  1
2009 Kersten RD, Dorrestein PC. Secondary metabolomics: natural products mass spectrometry goes global. Acs Chemical Biology. 4: 599-601. PMID 19817465 DOI: 10.1021/cb900187p  1
2009 Hughes CC, Yang YL, Liu WT, Dorrestein PC, La Clair JJ, Fenical W. Marinopyrrole A target elucidation by acyl dye transfer. Journal of the American Chemical Society. 131: 12094-6. PMID 19673475 DOI: 10.1021/ja903149u  1
2009 Ng J, Bandeira N, Liu WT, Ghassemian M, Simmons TL, Gerwick WH, Linington R, Dorrestein PC, Pevzner PA. Dereplication and de novo sequencing of nonribosomal peptides. Nature Methods. 6: 596-9. PMID 19597502 DOI: 10.1038/nmeth.1350  1
2009 Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Acyltransferase mediated polyketide release from a fungal megasynthase. Journal of the American Chemical Society. 131: 8388-9. PMID 19530726 DOI: 10.1021/ja903203g  1
2009 O'Hayre M, Salanga CL, Dorrestein PC, Handel TM. Phosphoproteomic analysis of chemokine signaling networks. Methods in Enzymology. 460: 331-46. PMID 19446733 DOI: 10.1016/S0076-6879(09)05216-1  1
2009 Esquenazi E, Dorrestein PC, Gerwick WH. Probing marine natural product defenses with DESI-imaging mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 106: 7269-70. PMID 19416917 DOI: 10.1073/pnas.0902840106  1
2009 Liu WT, Ng J, Meluzzi D, Bandeira N, Gutierrez M, Simmons TL, Schultz AW, Linington RG, Moore BS, Gerwick WH, Pevzner PA, Dorrestein PC. Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Analytical Chemistry. 81: 4200-9. PMID 19413302 DOI: 10.1021/ac900114t  1
2009 Burns KE, Liu WT, Boshoff HI, Dorrestein PC, Barry CE. Proteasomal protein degradation in Mycobacteria is dependent upon a prokaryotic ubiquitin-like protein. The Journal of Biological Chemistry. 284: 3069-75. PMID 19028679 DOI: 10.1074/jbc.M808032200  1
2008 Pouwels LJ, Zhang L, Chan NH, Dorrestein PC, Wachter RM. Kinetic isotope effect studies on the de novo rate of chromophore formation in fast- and slow-maturing GFP variants. Biochemistry. 47: 10111-22. PMID 18759496 DOI: 10.1021/bi8007164  1
2008 Esquenazi E, Coates C, Simmons L, Gonzalez D, Gerwick WH, Dorrestein PC. Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. Molecular Biosystems. 4: 562-70. PMID 18493654 DOI: 10.1039/b720018h  1
2008 Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/pnas.0801338105  1
2008 Ngo JC, Giang K, Chakrabarti S, Ma CT, Huynh N, Hagopian JC, Dorrestein PC, Fu XD, Adams JA, Ghosh G. A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Molecular Cell. 29: 563-76. PMID 18342604 DOI: 10.1016/j.molcel.2007.12.017  1
2008 Hanes JW, Burns KE, Hilmey DG, Chatterjee A, Dorrestein PC, Begley TP. Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate. Journal of the American Chemical Society. 130: 3043-52. PMID 18271580 DOI: 10.1021/ja076604l  1
2008 Simmons TL, Coates RC, Clark BR, Engene N, Gonzalez D, Esquenazi E, Dorrestein PC, Gerwick WH. Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages. Proceedings of the National Academy of Sciences of the United States of America. 105: 4587-94. PMID 18250337 DOI: 10.1073/pnas.0709851105  1
2008 Zhang J, Van Lanen SG, Ju J, Liu W, Dorrestein PC, Li W, Kelleher NL, Shen B. A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 1460-5. PMID 18223152 DOI: 10.1073/pnas.0711625105  1
2008 Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorganic & Medicinal Chemistry Letters. 18: 3107-11. PMID 18006314 DOI: 10.1016/j.bmcl.2007.10.104  1
2007 Calderone CT, Iwig DF, Dorrestein PC, Kelleher NL, Walsh CT. Incorporation of nonmethyl branches by isoprenoid-like logic: multiple beta-alkylation events in the biosynthesis of myxovirescin A1. Chemistry & Biology. 14: 835-46. PMID 17656320 DOI: 10.1016/j.chembiol.2007.06.008  1
2007 Winter JM, Moffitt MC, Zazopoulos E, McAlpine JB, Dorrestein PC, Moore BS. Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster. The Journal of Biological Chemistry. 282: 16362-8. PMID 17392281 DOI: 10.1074/jbc.M611046200  1
2007 Yin J, Straight PD, Hrvatin S, Dorrestein PC, Bumpus SB, Jao C, Kelleher NL, Kolter R, Walsh CT. Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display. Chemistry & Biology. 14: 303-12. PMID 17379145 DOI: 10.1016/j.chembiol.2007.01.006  1
2006 Dorrestein PC, Kelleher NL. Dissecting non-ribosomal and polyketide biosynthetic machineries using electrospray ionization Fourier-Transform mass spectrometry. Natural Product Reports. 23: 893-918. PMID 17119639 DOI: 10.1039/b511400b  1
2006 Dorrestein PC, Bumpus SB, Calderone CT, Garneau-Tsodikova S, Aron ZD, Straight PD, Kolter R, Walsh CT, Kelleher NL. Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry. 45: 12756-66. PMID 17042494 DOI: 10.1021/bi061169d  1
2006 Garneau-Tsodikova S, Dorrestein PC, Kelleher NL, Walsh CT. Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J. Journal of the American Chemical Society. 128: 12600-1. PMID 17002325 DOI: 10.1021/ja063611l  1
2006 Dorrestein PC, Van Lanen SG, Li W, Zhao C, Deng Z, Shen B, Kelleher NL. The bifunctional glyceryl transferase/phosphatase OzmB belonging to the HAD superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis. Journal of the American Chemical Society. 128: 10386-7. PMID 16895402 DOI: 10.1021/ja0639362  1
2006 Van Lanen SG, Lin S, Dorrestein PC, Kelleher NL, Shen B. Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027. The Journal of Biological Chemistry. 281: 29633-40. PMID 16887797 DOI: 10.1074/jbc.M605887200  1
2006 Calderone CT, Kowtoniuk WE, Kelleher NL, Walsh CT, Dorrestein PC. Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8977-82. PMID 16757561 DOI: 10.1073/pnas.0603148103  1
2006 Hicks LM, Mazur MT, Miller LM, Dorrestein PC, Schnarr NA, Khosla C, Kelleher NL. Investigating nonribosomal peptide and polyketide biosynthesis by direct detection of intermediates on >70 kDa polypeptides by using Fourier-transform mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 7: 904-7. PMID 16642537 DOI: 10.1002/cbic.200500416  1
2006 Howarth M, Chinnapen DJ, Gerrow K, Dorrestein PC, Grandy MR, Kelleher NL, El-Husseini A, Ting AY. A monovalent streptavidin with a single femtomolar biotin binding site. Nature Methods. 3: 267-73. PMID 16554831 DOI: 10.1038/nmeth861  1
2006 Dorrestein PC, Blackhall J, Straight PD, Fischbach MA, Garneau-Tsodikova S, Edwards DJ, McLaughlin S, Lin M, Gerwick WH, Kolter R, Walsh CT, Kelleher NL. Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry. 45: 1537-46. PMID 16460000 DOI: 10.1021/bi052333k  1
2005 Aron ZD, Dorrestein PC, Blackhall JR, Kelleher NL, Walsh CT. Characterization of a new tailoring domain in polyketide biogenesis: the amine transferase domain of MycA in the mycosubtilin gene cluster. Journal of the American Chemical Society. 127: 14986-7. PMID 16248612 DOI: 10.1021/ja055247g  1
2005 Dorrestein PC, Yeh E, Garneau-Tsodikova S, Kelleher NL, Walsh CT. Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13843-8. PMID 16162666 DOI: 10.1073/pnas.0506964102  1
2005 Burns KE, Baumgart S, Dorrestein PC, Zhai H, McLafferty FW, Begley TP. Reconstitution of a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. Journal of the American Chemical Society. 127: 11602-3. PMID 16104727 DOI: 10.1021/ja053476x  1
2005 Van Lanen SG, Dorrestein PC, Christenson SD, Liu W, Ju J, Kelleher NL, Shen B. Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates. Journal of the American Chemical Society. 127: 11594-5. PMID 16104723 DOI: 10.1021/ja052871k  1
2005 Zhai H, Dorrestein PC, Chatterjee A, Begley TP, McLafferty FW. Simultaneous kinetic characterization of multiple protein forms by top down mass spectrometry. Journal of the American Society For Mass Spectrometry. 16: 1052-9. PMID 15914018 DOI: 10.1016/j.jasms.2005.02.016  1
2005 Garneau S, Dorrestein PC, Kelleher NL, Walsh CT. Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A1 biosynthesis. Biochemistry. 44: 2770-80. PMID 15723521 DOI: 10.1021/bi0476329  1
2004 Dorrestein PC, Zhai H, McLafferty FW, Begley TP. The biosynthesis of the thiazole phosphate moiety of thiamin: the sulfur transfer mediated by the sulfur carrier protein ThiS. Chemistry & Biology. 11: 1373-81. PMID 15489164 DOI: 10.1016/j.chembiol.2004.08.009  1
2004 Settembre EC, Dorrestein PC, Zhai H, Chatterjee A, McLafferty FW, Begley TP, Ealick SE. Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex. Biochemistry. 43: 11647-57. PMID 15362849 DOI: 10.1021/bi0488911  1
2004 Dorrestein PC, Zhai H, Taylor SV, McLafferty FW, Begley TP. The biosynthesis of the thiazole phosphate moiety of thiamin (vitamin B1): the early steps catalyzed by thiazole synthase. Journal of the American Chemical Society. 126: 3091-6. PMID 15012138 DOI: 10.1021/ja039616p  1
2003 Park JH, Dorrestein PC, Zhai H, Kinsland C, McLafferty FW, Begley TP. Biosynthesis of the thiazole moiety of thiamin pyrophosphate (vitamin B1). Biochemistry. 42: 12430-8. PMID 14567704 DOI: 10.1021/bi034902z  1
2003 Dorrestein PC, Poole K, Begley TP. Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade. Organic Letters. 5: 2215-7. PMID 12816412 DOI: 10.1021/ol034531e  1
2003 Maggio-Hall LA, Dorrestein PC, Escalante-Semerena JC, Begley TP. Formation of the dimethylbenzimidazole ligand of coenzyme B(12) under physiological conditions by a facile oxidative cascade. Organic Letters. 5: 2211-3. PMID 12816411 DOI: 10.1021/ol034530m  1
2003 Settembre EC, Dorrestein PC, Park JH, Augustine AM, Begley TP, Ealick SE. Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis. Biochemistry. 42: 2971-81. PMID 12627963 DOI: 10.1021/bi026916v  1
2002 Anand R, Dorrestein PC, Kinsland C, Begley TP, Ealick SE. Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution. Biochemistry. 41: 7659-69. PMID 12056897 DOI: 10.1021/bi0200965  1
2001 Mansour G, Creedon W, Dorrestein PC, Maxka J, MacDonald JC, Helburn R. Synthesis and physical characterization of some new hydrophobic forms of the solvatochromic N,N-dialkyl-p-nitroanilines. The Journal of Organic Chemistry. 66: 4050-4. PMID 11375035 DOI: 10.1021/jo0014764  1
2001 MacDonald JC, Dorrestein PC, Pilley MM. Design of supramolecular layers via self-assembly of imidazole and carboxylic acids Crystal Growth and Design. 1: 29-38.  1
2000 MacDonald JC, Dorrestein PC, Pilley MM, Foote MM, Lundburg JL, Henning RW, Schultz AJ, Manson JL. Design of layered crystalline materials using coordination chemistry and hydrogen bonds Journal of the American Chemical Society. 122: 11692-11702. DOI: 10.1021/ja002102v  1
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