Michael D. Burkart - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Natural product synthesis/biosynthesis, Biological chemistry and enzymology, Metabolic engineering
Website:
http://www-chem.ucsd.edu/faculty/profiles/burkart_michael_d.html

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Re RN, Proessdorf JC, La Clair JJ, Subileau M, Burkart MD. Tailoring chemoenzymatic oxidation via in situ peracids. Organic & Biomolecular Chemistry. PMID 31650153 DOI: 10.1039/c9ob01814j  0.88
2019 Milligan JC, Lee DJ, Jackson DR, Schaub AJ, Beld J, Barajas JF, Hale JJ, Luo R, Burkart MD, Tsai SC. Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nature Chemical Biology. PMID 31209348 DOI: 10.1038/s41589-019-0301-y  0.8
2019 Sztain T, Patel A, Lee DJ, Davis T, McCammon JA, Burkart MD. One atom matters: modifying the thioester linkage affects structure of the acyl carrier protein. Angewandte Chemie (International Ed. in English). PMID 31140212 DOI: 10.1002/anie.201903815  0.48
2018 Tallorin L, Wang J, Kim WE, Sahu S, Kosa NM, Yang P, Thompson M, Gilson MK, Frazier PI, Burkart MD, Gianneschi NC. Discovering de novo peptide substrates for enzymes using machine learning. Nature Communications. 9: 5253. PMID 30531862 DOI: 10.1038/s41467-018-07717-6  0.88
2018 Chan WC, León B, Krug KA, Patel A, La Clair JJ, Burkart MD. Daedal Facets of Splice Modulator Optimization. Acs Medicinal Chemistry Letters. 9: 1070-1072. PMID 30429946 DOI: 10.1021/acsmedchemlett.8b00456  0.88
2018 Chen A, Re RN, Burkart MD. Type II fatty acid and polyketide synthases: deciphering protein-protein and protein-substrate interactions. Natural Product Reports. PMID 30046786 DOI: 10.1039/c8np00040a  0.44
2018 Michaud JM, Thompson LR, Kaul D, Espinoza JL, Richter RA, Xu ZZ, Lee C, Pham KM, Beall CM, Malfatti F, Azam F, Knight R, Burkart MD, Dupont CL, Prather KA. Taxon-specific aerosolization of bacteria and viruses in an experimental ocean-atmosphere mesocosm. Nature Communications. 9: 2017. PMID 29789621 DOI: 10.1038/s41467-018-04409-z  0.72
2018 Vickery CR, Cardenas J, Bowman M, Burkart MD, Da Silva NA, Noel JP. A coupled in vitro/in vivo approach for engineering a heterologous Type III PKS to enhance polyketide biosynthesis in Saccharomyces cerevisiae. Biotechnology and Bioengineering. PMID 29457628 DOI: 10.1002/bit.26564  1
2017 Finzel K, Beld J, Burkart MD, Charkoudian LK. Utilizing Mechanistic Cross-Linking Technology to Study Protein-Protein Interactions: An Experiment Designed for an Undergraduate Biochemistry Lab. Journal of Chemical Education. 94: 375-379. PMID 29255327 DOI: 10.1021/acs.jchemed.6b00453  0.8
2017 Jaremko MJ, Lee DJ, Patel A, Winslow V, Opella SJ, McCammon JA, Burkart MD. Manipulating protein-protein interactions in NRPS type II PCPs. Biochemistry. PMID 28920687 DOI: 10.1021/acs.biochem.7b00884  0.48
2017 Barajas JF, Shakya G, Moreno G, Rivera H, Jackson DR, Topper CL, Vagstad AL, La Clair JJ, Townsend CA, Burkart MD, Tsai SC. Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484029 DOI: 10.1073/pnas.1609001114  0.88
2016 Mindrebo JT, Nartey CM, Seto Y, Burkart MD, Noel JP. Corrigendum to "Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom" [Curr Opin Struct Biol 2016, 41:233-246]. Current Opinion in Structural Biology. PMID 27884574 DOI: 10.1016/j.sbi.2016.11.008  0.88
2016 Shurin JB, Burkart MD, Mayfield SP, Smith VH. Recent progress and future challenges in algal biofuel production. F1000research. 5. PMID 27781084 DOI: 10.12688/f1000research.9217.1  0.44
2016 Mindrebo JT, Nartey CM, Seto Y, Burkart MD, Noel JP. Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom. Current Opinion in Structural Biology. 41: 233-246. PMID 27662376 DOI: 10.1016/j.sbi.2016.08.005  1
2016 Barajas JF, Finzel K, Valentic TR, Shakya G, Gamarra N, Martinez D, Meier JL, Vagstad AL, Newman AG, Townsend CA, Burkart MD, Tsai SC. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain. Angewandte Chemie (International Ed. in English). PMID 27653519 DOI: 10.1002/anie.201605401  0.96
2016 Crews LA, Balaian L, Delos Santos NP, Leu HS, Court AC, Lazzari E, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Kulidjian A, Storb R, Morris SR, Ball ED, Burkart MD, et al. RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell. PMID 27570067 DOI: 10.1016/j.stem.2016.08.003  0.88
2016 Kumar D, Kashyap MK, La Clair JJ, Villa R, Spaanderman I, Chien S, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Selectivity in Small Molecule Splicing Modulation. Acs Chemical Biology. PMID 27499047 DOI: 10.1021/acschembio.6b00399  0.88
2016 Rivera H, Dhar S, La Clair JJ, Tsai SC, Burkart MD. An unusual intramolecular trans-amidation. Tetrahedron. 72: 3605-3608. PMID 27346894 DOI: 10.1016/j.tet.2016.01.062  1
2016 Koo HJ, Vickery CR, Xu Y, Louie GV, O'Maille PE, Bowman M, Nartey CM, Burkart MD, Noel JP. Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. The Journal of Antibiotics. PMID 27328867 DOI: 10.1038/ja.2016.68  1
2016 Uranga CC, Beld J, Mrse A, Córdova-Guerrero I, Burkart MD, Hernández-Martínez R. Data from mass spectrometry, NMR spectra, GC-MS of fatty acid esters produced by Lasiodiplodia theobromae. Data in Brief. 8: 31-39. PMID 27274528 DOI: 10.1016/j.dib.2016.05.003  0.8
2016 Foley TL, Dorjsuren D, Dexheimer TS, Burkart MD, Wight WC, Simeonov A. A Platform to Enable the Pharmacological Profiling of Small Molecules in Gel-Based Electrophoretic Mobility Shift Assays. Journal of Biomolecular Screening. PMID 27269812 DOI: 10.1177/1087057116652895  0.88
2016 Finzel K, Burkart MD. Traffic Control in Modular Polyketide Synthases. Acs Central Science. 2: 9-11. PMID 27163020 DOI: 10.1021/acscentsci.6b00007  0.68
2016 Dhar S, La Clair JJ, León B, Hammons JC, Yu Z, Kashyap MK, Castro JE, Burkart MD. A Carbohydrate-Derived Splice Modulator. Journal of the American Chemical Society. PMID 27058259 DOI: 10.1021/jacs.5b13427  1
2016 Tallorin L, Finzel K, Nguyen Q, Beld J, La Clair JJ, Burkart MD. Trapping of the Enoyl-Acyl Carrier Protein Reductase • Acyl Carrier Protein Interaction. Journal of the American Chemical Society. PMID 26938266 DOI: 10.1021/jacs.5b13456  1
2016 Uranga CC, Beld J, Mrse A, Córdova-Guerrero I, Burkart MD, Hernández-Martínez R. Fatty acid esters produced by Lasiodiplodia theobromae function as growth regulators in tobacco seedlings. Biochemical and Biophysical Research Communications. PMID 26926564 DOI: 10.1016/j.bbrc.2016.02.104  1
2016 Beld J, Abbriano R, Finzel K, Hildebrand M, Burkart MD. Probing fatty acid metabolism in bacteria, cyanobacteria, green microalgae and diatoms with natural and unnatural fatty acids. Molecular Biosystems. PMID 26886879 DOI: 10.1039/c5mb00804b  1
2016 Vickery CR, La Clair JJ, Burkart MD, Noel JP. Harvesting the biosynthetic machineries that cultivate a variety of indispensable plant natural products. Current Opinion in Chemical Biology. 31: 66-73. PMID 26851514 DOI: 10.1016/j.cbpa.2016.01.008  1
2015 Moynié L, Hope AG, Finzel K, Schmidberger J, Leckie SM, Schneider G, Burkart MD, Smith AD, Gray DW, Naismith JH. A substrate mimic allows high throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA. Journal of Molecular Biology. PMID 26562505 DOI: 10.1016/j.jmb.2015.10.027  1
2015 Finzel K, Nguyen C, Jackson DR, Gupta A, Tsai SC, Burkart MD. Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA. Chemistry & Biology. PMID 26526101 DOI: 10.1016/j.chembiol.2015.09.009  1
2015 Jaremko MJ, Lee DJ, Opella SJ, Burkart MD. Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. Journal of the American Chemical Society. 137: 11546-9. PMID 26340431 DOI: 10.1021/jacs.5b04525  1
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens. Ebiomedicine. 2: 690-8. PMID 26288841 DOI: 10.1016/j.ebiom.2015.05.021  0.72
2015 Cahill JF, Darlington TK, Fitzgerald C, Schoepp NG, Beld J, Burkart MD, Prather KA. Online Analysis of Single Cyanobacteria and Algae Cells under Nitrogen-Limited Conditions Using Aerosol Time-of-Flight Mass Spectrometry. Analytical Chemistry. 87: 8039-46. PMID 26237223 DOI: 10.1021/acs.analchem.5b02326  0.8
2015 Ferreira-Camargo LS, Tran M, Beld J, Burkart MD, Mayfield SP. Selenocystamine improves protein accumulation in chloroplasts of eukaryotic green algae. Amb Express. 5: 126. PMID 26137911 DOI: 10.1186/s13568-015-0126-3  1
2015 Kashyap MK, Kumar D, Villa R, La Clair JJ, Benner C, Sasik R, Jones H, Ghia EM, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 100: 945-54. PMID 25862704 DOI: 10.3324/haematol.2014.122069  1
2015 Finzel K, Lee DJ, Burkart MD. Using modern tools to probe the structure-function relationship of fatty acid synthases. Chembiochem : a European Journal of Chemical Biology. 16: 528-47. PMID 25676190 DOI: 10.1002/cbic.201402578  1
2015 Konno S, Ishikawa F, Suzuki T, Dohmae N, Burkart MD, Kakeya H. Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases. Chemical Communications (Cambridge, England). 51: 2262-5. PMID 25563804 DOI: 10.1039/c4cc09412c  1
2015 Beld J, Lee DJ, Burkart MD. Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Molecular Biosystems. 11: 38-59. PMID 25360565 DOI: 10.1039/c4mb00443d  1
2015 Schoepp NG, Wong W, Mayfield SP, Burkart MD. Bulk solvent extraction of biomass slurries using a lipid trap Rsc Advances. 5: 57038-57044. DOI: 10.1039/c5ra11444f  1
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens Ebiomedicine. DOI: 10.1016/j.ebiom.2015.05.021  0.72
2015 Schoepp NG, Ansari WS, Dallwig JA, Gale D, Burkart MD, Mayfield SP. Rapid estimation of protein, lipid, and dry weight in microalgae using a portable LED fluorometer Algal Research. 11: 108-112. DOI: 10.1016/j.algal.2015.06.008  0.44
2014 Kosa NM, Pham KM, Burkart MD. Chemoenzymatic exchange of phosphopantetheine on protein and peptide. Chemical Science (Royal Society of Chemistry : 2010). 5: 1179-1186. PMID 26998215 DOI: 10.1039/C3SC53154F  0.88
2014 Ku TH, Sahu S, Kosa NM, Pham KM, Burkart MD, Gianneschi NC. Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials. Journal of the American Chemical Society. 136: 17378-81. PMID 25468257 DOI: 10.1021/ja509827s  1
2014 Shakya G, Rivera H, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, ... Burkart MD, et al. Modeling linear and cyclic PKS intermediates through atom replacement. Journal of the American Chemical Society. 136: 16792-9. PMID 25406716 DOI: 10.1021/ja5064857  1
2014 Beld J, Cang H, Burkart MD. Visualizing the chain-flipping mechanism in fatty-acid biosynthesis. Angewandte Chemie (International Ed. in English). 53: 14456-61. PMID 25354391 DOI: 10.1002/anie.201408576  1
2014 Beld J, Finzel K, Burkart MD. Versatility of acyl-acyl carrier protein synthetases. Chemistry & Biology. 21: 1293-9. PMID 25308274 DOI: 10.1016/j.chembiol.2014.08.015  1
2014 Beld J, Blatti JL, Behnke C, Mendez M, Burkart MD. Evolution of acyl-ACP-thioesterases and β-ketoacyl-ACP-synthases revealed by protein-protein interactions. Journal of Applied Phycology. 26: 1619-1629. PMID 25110394 DOI: 10.1007/s10811-013-0203-4  1
2014 Vickery CR, Kosa NM, Casavant EP, Duan S, Noel JP, Burkart MD. Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of Mycobacteria. Acs Chemical Biology. 9: 1939-44. PMID 24963544 DOI: 10.1021/cb500263p  1
2014 Schoepp NG, Stewart RL, Sun V, Quigley AJ, Mendola D, Mayfield SP, Burkart MD. System and method for research-scale outdoor production of microalgae and cyanobacteria. Bioresource Technology. 166: 273-81. PMID 24926599 DOI: 10.1016/j.biortech.2014.05.046  1
2014 Rothmann M, Kosa NM, Burkart MD. Resin supported acyl carrier protein labeling strategies. Rsc Advances. 4: 9092-9097. PMID 24818001 DOI: 10.1039/C3RA47847E  1
2014 Foley TL, Rai G, Yasgar A, Daniel T, Baker HL, Attene-Ramos M, Kosa NM, Leister W, Burkart MD, Jadhav A, Simeonov A, Maloney DJ. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. Journal of Medicinal Chemistry. 57: 1063-78. PMID 24450337 DOI: 10.1021/jm401752p  1
2014 Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella SJ, Tsai SC, Burkart MD. Trapping the dynamic acyl carrier protein in fatty acid biosynthesis. Nature. 505: 427-31. PMID 24362570 DOI: 10.1038/nature12810  0.72
2014 Beld J, Sonnenschein EC, Vickery CR, Noel JP, Burkart MD. The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life. Natural Product Reports. 31: 61-108. PMID 24292120 DOI: 10.1039/c3np70054b  1
2014 Kosa NM, Foley TL, Burkart MD. Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors. The Journal of Antibiotics. 67: 113-20. PMID 24192555 DOI: 10.1038/ja.2013.106  1
2014 Kosa NM, Pham KM, Burkart MD. Chemoenzymatic exchange of phosphopantetheine on protein and peptide Chemical Science. 5: 1179-1186. DOI: 10.1039/c3sc53154f  1
2014 Bruegger J, Caldara G, Beld J, Burkart MD, Tsai SCS. Polyketide Synthase: Sequence, Structure, and Function Natural Products: Discourse, Diversity, and Design. 219-243. DOI: 10.1002/9781118794623.ch12  1
2013 Thomsen M, Vogensen SB, Buchardt J, Burkart MD, Clausen RP. Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs. Organic & Biomolecular Chemistry. 11: 7606-10. PMID 24100405 DOI: 10.1039/c3ob41702f  1
2013 Nonejuie P, Burkart M, Pogliano K, Pogliano J. Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: 16169-74. PMID 24046367 DOI: 10.1073/pnas.1311066110  1
2013 Javidpour P, Bruegger J, Srithahan S, Korman TP, Crump MP, Crosby J, Burkart MD, Tsai SC. The determinants of activity and specificity in actinorhodin type II polyketide ketoreductase. Chemistry & Biology. 20: 1225-34. PMID 24035284 DOI: 10.1016/j.chembiol.2013.07.016  1
2013 Bruegger J, Haushalter RW, Haushalter B, Vagstad AL, Vagstad A, Shakya G, Mih N, Townsend CA, Burkart MD, Tsai SC. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers. Chemistry & Biology. 20: 1135-46. PMID 23993461 DOI: 10.1016/j.chembiol.2013.07.012  1
2013 Villa R, Kashyap MK, Kumar D, Kipps TJ, Castro JE, La Clair JJ, Burkart MD. Stabilized cyclopropane analogs of the splicing inhibitor FD-895. Journal of Medicinal Chemistry. 56: 6576-82. PMID 23919277 DOI: 10.1021/jm400861t  1
2013 Burkart MD, Mayfield SP. Biofuels for the 21st century. Current Opinion in Chemical Biology. 17: 436-8. PMID 23722079 DOI: 10.1016/j.cbpa.2013.05.003  1
2013 Ishikawa F, Haushalter RW, Lee DJ, Finzel K, Burkart MD. Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase. Journal of the American Chemical Society. 135: 8846-9. PMID 23718183 DOI: 10.1021/ja4042059  1
2013 Blatti JL, Michaud J, Burkart MD. Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Current Opinion in Chemical Biology. 17: 496-505. PMID 23683348 DOI: 10.1016/j.cbpa.2013.04.007  1
2013 Yu WL, Jones BD, Kang M, Hammons JC, La Clair JJ, Burkart MD. Spirohexenolide A targets human macrophage migration inhibitory factor (hMIF). Journal of Natural Products. 76: 817-23. PMID 23659282 DOI: 10.1021/np3004497  1
2013 Lipson JM, Thomsen M, Moore BS, Clausen RP, La Clair JJ, Burkart MD. A tandem chemoenzymatic methylation by S-adenosyl-L-methionine. Chembiochem : a European Journal of Chemical Biology. 14: 950-3. PMID 23650044 DOI: 10.1002/cbic.201300221  1
2013 Rothmann M, Kang M, Villa R, Ntai I, La Clair JJ, Kelleher NL, Chapman E, Burkart MD. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. 135: 5962-5. PMID 23550886 DOI: 10.1021/ja400795m  1
2013 Stewart C, Vickery CR, Burkart MD, Noel JP. Confluence of structural and chemical biology: plant polyketide synthases as biocatalysts for a bio-based future. Current Opinion in Plant Biology. 16: 365-72. PMID 23481348 DOI: 10.1016/j.pbi.2013.02.004  1
2013 Rodionova IA, Leyn SA, Burkart MD, Boucher N, Noll KM, Osterman AL, Rodionov DA. Novel inositol catabolic pathway in Thermotoga maritima. Environmental Microbiology. 15: 2254-66. PMID 23441918 DOI: 10.1111/1462-2920.12096  1
2012 Villa R, Mandel AL, Jones BD, La Clair JJ, Burkart MD. Structure of FD-895 revealed through total synthesis. Organic Letters. 14: 5396-9. PMID 23072504 DOI: 10.1021/ol3023006  1
2012 Blatti JL, Beld J, Behnke CA, Mendez M, Mayfield SP, Burkart MD. Manipulating fatty acid biosynthesis in microalgae for biofuel through protein-protein interactions. Plos One. 7: e42949. PMID 23028438 DOI: 10.1371/journal.pone.0042949  1
2012 Kosa NM, Haushalter RW, Smith AR, Burkart MD. Reversible labeling of native and fusion-protein motifs. Nature Methods. 9: 981-4. PMID 22983458 DOI: 10.1038/nmeth.2175  1
2012 Hur GH, Vickery CR, Burkart MD. Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology. Natural Product Reports. 29: 1074-98. PMID 22802156 DOI: 10.1039/c2np20025b  1
2012 van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chemistry & Biology. 19: 559-71. PMID 22633408 DOI: 10.1016/j.chembiol.2012.03.013  1
2012 Ishikawa F, Haushalter RW, Burkart MD. Dehydratase-specific probes for fatty acid and polyketide synthases. Journal of the American Chemical Society. 134: 769-72. PMID 22188524 DOI: 10.1021/ja2082334  1
2012 Rothmann M, Niessen S, Haushalter RW, Cravatt BF, Burkart MD. Resin-based investigation of acyl carrier protein interaction networks in Escherichia coli. Bioorganic & Medicinal Chemistry. 20: 667-71. PMID 22104437 DOI: 10.1016/j.bmc.2011.10.053  1
2012 Limtiaco JK, Pomeroy RS, Burkart M, Mayfield S. Educating and developing workers for the green economy Biofuels. 3: 119-121. DOI: 10.4155/BFS.12.9  1
2012 Blatti JL, Burkart MD. Releasing stored solar energy within pond scum: Biodiesel from algal lipids Journal of Chemical Education. 89: 239-242. DOI: 10.1021/ed200098c  1
2011 Yu WL, Ansari W, Schoepp NG, Hannon MJ, Mayfield SP, Burkart MD. Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microbial Cell Factories. 10: 91. PMID 22047615 DOI: 10.1186/1475-2859-10-91  1
2011 La Clair JJ, Rheingold AL, Burkart MD. Ganodone, a bioactive benzofuran from the fruiting bodies of Ganoderma tsugae. Journal of Natural Products. 74: 2045-51. PMID 21939217 DOI: 10.1021/np200361y  1
2011 Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, et al. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America. 108: 8815-20. PMID 21555588 DOI: 10.1073/pnas.1101137108  1
2011 Haushalter RW, Filipp FV, Ko KS, Yu R, Opella SJ, Burkart MD. Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. Acs Chemical Biology. 6: 413-8. PMID 21268653 DOI: 10.1021/cb200004k  1
2011 Worthington AS, Hur GH, Burkart MD. Activity-guided engineering of natural product carrier proteins. Molecular Biosystems. 7: 365-70. PMID 21184004 DOI: 10.1039/c0mb00251h  1
2011 Meier JL, Burkart MD. Proteomic analysis of polyketide and nonribosomal peptide biosynthesis. Current Opinion in Chemical Biology. 15: 48-56. PMID 21087894 DOI: 10.1016/j.cbpa.2010.10.021  1
2011 Meier JL, Patel AD, Niessen S, Meehan M, Kersten R, Yang JY, Rothmann M, Cravatt BF, Dorrestein PC, Burkart MD, Bafna V. Practical 4'-phosphopantetheine active site discovery from proteomic samples. Journal of Proteome Research. 10: 320-9. PMID 21067235 DOI: 10.1021/pr100953b  1
2010 Reyes CP, La Clair JJ, Burkart MD. Metabolic probes for imaging endosymbiotic bacteria within toxic dinoflagellates. Chemical Communications (Cambridge, England). 46: 8151-3. PMID 20927429 DOI: 10.1039/c0cc02876b  1
2010 Jones BD, La Clair JJ, Moore CE, Rheingold AL, Burkart MD. Convergent route to the spirohexenolide macrocycle. Organic Letters. 12: 4516-9. PMID 20849075 DOI: 10.1021/ol1018163  1
2010 Ko KS, Alexander MD, Fontaine SD, Biggs-Houck JE, La Clair JJ, Burkart MD. Synthetic studies on the mycolactone core. Organic & Biomolecular Chemistry. 8: 5159-65. PMID 20844795 DOI: 10.1039/c0ob00540a  1
2010 Yu WL, Guizzunti G, Foley TL, Burkart MD, La Clair JJ. An optimized immunoaffinity fluorescent method for natural product target elucidation. Journal of Natural Products. 73: 1659-66. PMID 20836515 DOI: 10.1021/np100371k  1
2010 Foley TL, Yasgar A, Garcia CJ, Jadhav A, Simeonov A, Burkart MD. Preparation of FRET reporters to support chemical probe development. Organic & Biomolecular Chemistry. 8: 4601-6. PMID 20725690 DOI: 10.1039/c0ob00322k  1
2010 Meier JL, Haushalter RW, Burkart MD. A mechanism based protein crosslinker for acyl carrier protein dehydratases. Bioorganic & Medicinal Chemistry Letters. 20: 4936-9. PMID 20620055 DOI: 10.1016/j.bmcl.2010.06.028  1
2010 Worthington AS, Porter DF, Burkart MD. Mechanism-based crosslinking as a gauge for functional interaction of modular synthases. Organic & Biomolecular Chemistry. 8: 1769-72. PMID 20449476 DOI: 10.1039/b925966j  1
2010 Yasgar A, Foley TL, Jadhav A, Inglese J, Burkart MD, Simeonov A. A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular Biosystems. 6: 365-75. PMID 20094656 DOI: 10.1039/b913291k  1
2009 Foley TL, Young BS, Burkart MD. Phosphopantetheinyl transferase inhibition and secondary metabolism. The Febs Journal. 276: 7134-45. PMID 19895578 DOI: 10.1111/j.1742-4658.2009.07425.x  1
2009 Kang M, Jones BD, Mandel AL, Hammons JC, DiPasquale AG, Rheingold AL, La Clair JJ, Burkart MD. Isolation, structure elucidation, and antitumor activity of spirohexenolides A and B. The Journal of Organic Chemistry. 74: 9054-61. PMID 19883063 DOI: 10.1021/jo901826d  1
2009 Lear MJ, Simon O, Foley TL, Burkart MD, Baiga TJ, Noel JP, DiPasquale AG, Rheingold AL, La Clair JJ. Laetirobin from the parasitic growth of Laetiporus sulphureus on Robinia pseudoacacia. Journal of Natural Products. 72: 1980-7. PMID 19842686 DOI: 10.1021/np9002838  1
2009 Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, Burkart MD. An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. Acs Chemical Biology. 4: 948-57. PMID 19785476 DOI: 10.1021/cb9002128  1
2009 Najmabadi P, Lee HH, Aung T, Thuya A, Ng J, La Clair JJ, Burkart MD. Grafta: a 3D environment for biomolecular networks. International Journal of Bioinformatics Research and Applications. 5: 564-9. PMID 19778870 DOI: 10.1504/IJBRA.2009.028683  1
2009 Foley TL, Burkart MD. A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Analytical Biochemistry. 394: 39-47. PMID 19573516 DOI: 10.1016/j.ab.2009.06.037  1
2009 Meier JL, Burkart MD. The chemical biology of modular biosynthetic enzymes. Chemical Society Reviews. 38: 2012-45. PMID 19551180 DOI: 10.1039/b805115c  1
2009 Meier JL, Burkart MD. Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes. Methods in Enzymology. 458: 219-54. PMID 19374985 DOI: 10.1016/S0076-6879(09)04809-5  1
2009 Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, Burkart MD. Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis. Chemistry & Biology. 16: 372-81. PMID 19345117 DOI: 10.1016/j.chembiol.2009.02.009  1
2009 Mercer AC, Meier JL, Torpey JW, Burkart MD. In vivo modification of native carrier protein domains. Chembiochem : a European Journal of Chemical Biology. 10: 1091-100. PMID 19308927 DOI: 10.1002/cbic.200800838  1
2009 Burkart M, Tao J. Multimodular Synthases and Supporting Enzymes for Chemical Production Biocatalysis For the Pharmaceutical Industry: Discovery, Development, and Manufacturing. 273-303. DOI: 10.1002/9780470823163.ch13  1
2008 Mercer AC, Meier JL, Hur GH, Smith AR, Burkart MD. Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli. Bioorganic & Medicinal Chemistry Letters. 18: 5991-4. PMID 18701278 DOI: 10.1016/j.bmcl.2008.07.078  1
2008 Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD. Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem : a European Journal of Chemical Biology. 9: 2096-103. PMID 18666307 DOI: 10.1002/cbic.200800198  1
2008 Meier JL, Barrows-Yano T, Foley TL, Wike CL, Burkart MD. The unusual macrocycle forming thioesterase of mycolactone. Molecular Biosystems. 4: 663-71. PMID 18493665 DOI: 10.1039/b801397g  1
2008 Meier JL, Mercer AC, Burkart MD. Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. Journal of the American Chemical Society. 130: 5443-5. PMID 18376827 DOI: 10.1021/ja711263w  1
2008 Haushalter RW, Worthington AS, Hur GH, Burkart MD. An orthogonal purification strategy for isolating crosslinked domains of modular synthases. Bioorganic & Medicinal Chemistry Letters. 18: 3039-42. PMID 18249538 DOI: 10.1016/j.bmcl.2008.01.026  1
2008 Kapur S, Worthington A, Tang Y, Cane DE, Burkart MD, Khosla C. Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase. Bioorganic & Medicinal Chemistry Letters. 18: 3034-8. PMID 18243693 DOI: 10.1016/j.bmcl.2008.01.073  1
2008 Ko KS, Najmabadi P, La Clair JJ, Burkart MD. Affinity analyses on moldable optical polycarbonate. Chembiochem : a European Journal of Chemical Biology. 9: 201-5. PMID 18098256 DOI: 10.1002/cbic.200700468  1
2008 Najmabadi P, Ko KS, La Clair JJ, Burkart MD. A Method for Fabrication of Polycarbonate-Based Bioactive Platforms Jala - Journal of the Association For Laboratory Automation. 13: 284-288. DOI: 10.1016/j.jala.2008.07.003  1
2008 Burkart MD, Tao J. Multi-Modular Synthases as Tools of the Synthetic Chemist Multi-Step Enzyme Catalysis: Biotransformations and Chemoenzymatic Synthesis. 137-158. DOI: 10.1002/9783527623389.ch7  1
2007 Mandel AL, Jones BD, La Clair JJ, Burkart MD. A synthetic entry to pladienolide B and FD-895. Bioorganic & Medicinal Chemistry Letters. 17: 5159-64. PMID 17681759 DOI: 10.1016/j.bmcl.2007.06.094  1
2007 Mercer AC, Burkart MD. The ubiquitous carrier protein--a window to metabolite biosynthesis. Natural Product Reports. 24: 750-73. PMID 17653358 DOI: 10.1039/b603921a  1
2007 Worthington AS, Burkart MD. The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis. Acs Chemical Biology. 2: 152-4. PMID 17373761 DOI: 10.1021/cb700053g  1
2007 Najmabadi P, La Clair JJ, Burkart MD. A systems perspective to digital structures in molecular analysis. Organic & Biomolecular Chemistry. 5: 214-22. PMID 17205161 DOI: 10.1039/b614507h  1
2007 Foley TL, Burkart MD. Site-specific protein modification: advances and applications. Current Opinion in Chemical Biology. 11: 12-9. PMID 17189712 DOI: 10.1016/j.cbpa.2006.11.036  1
2006 Worthington AS, Rivera H, Torpey JW, Alexander MD, Burkart MD. Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. Acs Chemical Biology. 1: 687-91. PMID 17184132 DOI: 10.1021/cb6003965  1
2006 Alexander MD, Fontaine SD, La Clair JJ, Dipasquale AG, Rheingold AL, Burkart MD. Synthesis of the mycolactone core by ring-closing metathesis. Chemical Communications (Cambridge, England). 4602-4. PMID 17082856 DOI: 10.1039/b609408b  1
2006 Meier JL, Mercer AC, Rivera H, Burkart MD. Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. Journal of the American Chemical Society. 128: 12174-84. PMID 16967968 DOI: 10.1021/ja063217n  1
2006 La Clair JJ, Burkart MD. Geometry in digital molecular arrays. Organic & Biomolecular Chemistry. 4: 3052-5. PMID 16886071 DOI: 10.1039/b605411k  1
2006 Alexander MD, Burkart MD, Leonard MS, Portonovo P, Liang B, Ding X, Joullié MM, Gulledge BM, Aggen JB, Chamberlin AR, Sandler J, Fenical W, Cui J, Gharpure SJ, Polosukhin A, et al. A central strategy for converting natural products into fluorescent probes. Chembiochem : a European Journal of Chemical Biology. 7: 409-16. PMID 16432909 DOI: 10.1002/cbic.200500466  1
2006 Mercer AC, Burkart MD. Chemical expansion of cofactor activity. Nature Chemical Biology. 2: 8-10. PMID 16408081 DOI: 10.1038/nchembio0106-8  1
2006 Worthington AS, Burkart MD. One-pot chemo-enzymatic synthesis of reporter-modified proteins. Organic & Biomolecular Chemistry. 4: 44-6. PMID 16357994 DOI: 10.1039/b512735a  1
2005 Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate Chemistry. 16: 1352-5. PMID 16287229 DOI: 10.1021/bc050213j  1
2005 Clarke KM, Mercer AC, La Clair JJ, Burkart MD. In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. Journal of the American Chemical Society. 127: 11234-5. PMID 16089439 DOI: 10.1021/ja052911k  1
2005 Mercer AC, La Clair JJ, Burkart MD. Fluorescent multiplex analysis of carrier protein post-translational modification. Chembiochem : a European Journal of Chemical Biology. 6: 1335-7. PMID 15997462 DOI: 10.1002/cbic.200500051  1
2005 Clarke KM, La Clair JJ, Burkart MD. A three-component photoreversible tag for thiols. The Journal of Organic Chemistry. 70: 3709-11. PMID 15845011 DOI: 10.1021/jo0481396  1
2005 Mercer AC, Burkart MD. Enzyme-assisted antibiotic engineering--the Wright way. Chemistry & Biology. 12: 147-8. PMID 15734642 DOI: 10.1016/j.chembiol.2005.01.010  1
2004 Mandel AL, La Clair JJ, Burkart MD. Modular synthesis of pantetheine and phosphopantetheine. Organic Letters. 6: 4801-3. PMID 15606070 DOI: 10.1021/ol048853+  1
2004 Nyffeler PT, Durón SG, Burkart MD, Vincent SP, Wong CH. Selectfluor: mechanistic insight and applications. Angewandte Chemie (International Ed. in English). 44: 192-212. PMID 15578736 DOI: 10.1002/anie.200400648  1
2004 Merkel AB, Major LL, Errey JC, Burkart MD, Field RA, Walsh CT, Naismith JH. The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. The Journal of Biological Chemistry. 279: 32684-91. PMID 15159413 DOI: 10.1074/jbc.M404091200  1
2004 La Clair JJ, Foley TL, Schegg TR, Regan CM, Burkart MD. Manipulation of carrier proteins in antibiotic biosynthesis. Chemistry & Biology. 11: 195-201. PMID 15123281 DOI: 10.1016/j.chembiol.2004.02.010  1
2003 La Clair JJ, Burkart MD. Molecular screening on a compact disc. Organic & Biomolecular Chemistry. 1: 3244-9. PMID 14527159 DOI: 10.1039/b306391g  1
2003 Burkart MD. Metabolic engineering - A genetic toolbox for small molecule organic synthesis Organic and Biomolecular Chemistry. 1: 1-4.  1
2002 Kohli RM, Walsh CT, Burkart MD. Biomimetic synthesis and optimization of cyclic peptide antibiotics. Nature. 418: 658-61. PMID 12167866 DOI: 10.1038/nature00907  1
2002 Marshall CG, Burkart MD, Meray RK, Walsh CT. Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases. Biochemistry. 41: 8429-37. PMID 12081492 DOI: 10.1021/bi0202575  1
2002 Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH. Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 58: 1226-8. PMID 12077451 DOI: 10.1107/S0907444902007382  1
2002 Thomas MG, Burkart MD, Walsh CT. Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis. Chemistry & Biology. 9: 171-84. PMID 11880032 DOI: 10.1016/S1074-5521(02)00100-X  1
2001 Luo L, Burkart MD, Stachelhaus T, Walsh CT. Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase. Journal of the American Chemical Society. 123: 11208-18. PMID 11697963 DOI: 10.1021/ja0166646  1
2001 Chen H, Thomas MG, O'Connor SE, Hubbard BK, Burkart MD, Walsh CT. Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics. Biochemistry. 40: 11651-9. PMID 11570865 DOI: 10.1021/bi0115434  1
2001 Marshall CG, Burkart MD, Keating TA, Walsh CT. Heterocycle formation in vibriobactin biosynthesis: alternative substrate utilization and identification of a condensed intermediate. Biochemistry. 40: 10655-63. PMID 11524010 DOI: 10.1021/bi010937s  1
2000 Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD. Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11942-7. PMID 11035791 DOI: 10.1073/pnas.210395097  1
2000 Burkart MD, Vincent SP, Düffels A, Murray BW, Ley SV, Wong CH. Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases. Bioorganic & Medicinal Chemistry. 8: 1937-46. PMID 11003139 DOI: 10.1016/S0968-0896(00)00139-5  1
2000 Burkart MD, Izumi M, Chapman E, Lin CH, Wong CH. Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides. The Journal of Organic Chemistry. 65: 5565-74. PMID 10970295 DOI: 10.1021/jo000266o  1
1999 Burkart MD, Wong CH. A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV. Analytical Biochemistry. 274: 131-7. PMID 10527506 DOI: 10.1006/abio.1999.4264  1
1999 Burkart MD, Izumi M, Wong CH. Enzymatic Regeneration of 3'-Phosphoadenosine-5'-Phosphosulfate Using Aryl Sulfotransferase for the Preparative Enzymatic Synthesis of Sulfated Carbohydrates. Angewandte Chemie (International Ed. in English). 38: 2747-2750. PMID 10508369 DOI: 10.1002/(SICI)1521-3773(19990917)38:18<2747::AID-ANIE2747>3.0.CO;2-2  1
1999 Vincent SP, Burkart MD, Tsai CY, Zhang Z, Wong CH. Electrophilic fluorination - Nucleophilic addition reaction mediated by selectfluor: Mechanistic studies and new applications Journal of Organic Chemistry. 64: 5264-5279. DOI: 10.1021/jo990686h  1
1999 Burkart MD, Vincent SP, Wong CH. An efficient synthesis of CMP-3-fluoroneuraminic acid Chemical Communications. 1525-1526.  1
1997 Murray BW, Wittmann V, Burkart MD, Hung SC, Wong CH. Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. Biochemistry. 36: 823-31. PMID 9020780 DOI: 10.1021/bi962284z  1
1997 Burkart MD, Zhang Z, Hung SC, Wong CH. A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor Journal of the American Chemical Society. 119: 11743-11746. DOI: 10.1021/ja9723904  1
1997 Whitmire KH, Hutchison JC, Burkart MD, Lee J, Ezenwa S, Mcknight AL, Jones CM, Bachman RE, Norman NC, Fisher GA, Pickett NL. Main group-transition metal carbonyl complexes Inorganic Syntheses. 31: 220-228.  1
1993 Jones CM, Burkart MD, Bachman RE, Serra DL, Hwu SJ, Whitmire KH. Hypervalent bismuth alkoxide dimer complexes: Syntheses, structures, and thermal decompositions of [Bi(OCH(CF3)2)2(μ-OCH(CF3) 2)(THF)]2 and [Bi(OC6F5)2(μ-OC6F 5)XB]2·zY (X = Y = C7H ... Inorganic Chemistry. 32: 5136-5144.  1
1992 Jones CM, Burkart MD, Whitmire KH. Novel aryloxybismuthoxide clusters: X-ray crystal structures of Bi 6(μ3-O)7(μ3-OC 6F5){Bi(OC6F5)4} 3(thf)2 and Bi6(μ3-O) 7(μ3-OC6F5){Bi(OC 6F5).. Journal of the Chemical Society, Chemical Communications. 1638-1639. DOI: 10.1039/C39920001638  1
1992 Jones CM, Burkart MD, Whitmire KH. Bismuth alkoxide dimer complexes containing planar Bi2(μ-OR)2 cores: Syntheses and structures of [{Bi[OCH(CF3)2]3(thf)}2] and [{Bi(OC6F5)3(C7H8)} 2] · 2C7H8 Angewandte Chemie (International Edition in English). 31: 451-452.  1
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