| Year |
Citation |
Score |
| 2024 |
Jiang Z, Chen JA, Mohamed OG, Huynh J, Chen A, Tripathi A, La Clair JJ, Burkart MD. Cryptic Cerulenin Rearrangement in Ketosynthase Covalent Inhibition. Journal of the American Chemical Society. PMID 38981108 DOI: 10.1021/jacs.4c05938 |
0.574 |
|
| 2024 |
Miyada MG, Choi Y, Stepanauskas R, Woyke T, La Clair JJ, Burkart MD. Fluorometric Analysis of Carrier-Protein-Dependent Biosynthesis through a Conformationally Sensitive Solvatochromic Pantetheinamide Probe. Acs Chemical Biology. 19: 1416-1425. PMID 38909314 DOI: 10.1021/acschembio.4c00169 |
0.357 |
|
| 2024 |
Chen A, Re RN, Davis TD, Tran K, Moriuchi YW, Wu S, La Clair JJ, Louie GV, Bowman ME, Clarke DJ, Mackay CL, Campopiano DJ, Noel JP, Burkart MD. Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society. PMID 38176024 DOI: 10.1021/jacs.3c10181 |
0.715 |
|
| 2023 |
Suo Y, Chen A, La Clair JJ, Burkart MD. Substrate Sequestration and Chain Flipping in Human Mitochondrial Acyl Carrier Protein. Biochemistry. PMID 38039071 DOI: 10.1021/acs.biochem.3c00447 |
0.579 |
|
| 2023 |
Jiang Z, Chen A, Chen J, Sekhon A, Louie GV, Noel JP, La Clair JJ, Burkart MD. Masked cerulenin enables a dual-site selective protein crosslink. Chemical Science. 14: 10925-10933. PMID 37829009 DOI: 10.1039/d3sc02864j |
0.727 |
|
| 2023 |
Sztain T, Corpuz JC, Bartholow TG, Sanlley Hernandez JO, Jiang Z, Mellor DA, Heberlig GW, La Clair JJ, McCammon JA, Burkart MD. Interface Engineering of Carrier-Protein-Dependent Metabolic Pathways. Acs Chemical Biology. 18: 2014-2022. PMID 37671411 DOI: 10.1021/acschembio.3c00238 |
0.34 |
|
| 2022 |
Chen A, Mindrebo JT, Davis TD, Kim WE, Katsuyama Y, Jiang Z, Ohnishi Y, Noel JP, Burkart MD. Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states. Acta Crystallographica. Section D, Structural Biology. 78: 1171-1179. PMID 36048156 DOI: 10.1107/S2059798322007434 |
0.684 |
|
| 2022 |
Chen A, Jiang Z, Burkart MD. Enzymology of standalone elongating ketosynthases. Chemical Science. 13: 4225-4238. PMID 35509474 DOI: 10.1039/d1sc07256k |
0.599 |
|
| 2022 |
Bartholow TG, Sztain T, Young MA, Lee DJ, Davis TD, Abagyan R, Burkart MD. Control of Unsaturation in Fatty Acid Biosynthesis by FabA. Biochemistry. PMID 35255690 DOI: 10.1021/acs.biochem.2c00094 |
0.341 |
|
| 2022 |
Kumar D, Kashyap MK, Yu Z, Spaanderman I, Villa R, Kipps TJ, La Clair JJ, Burkart MD, Castro JE. Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B. Aging. 14: 2081-2100. PMID 35230971 DOI: 10.18632/aging.203924 |
0.777 |
|
| 2022 |
Corpuz JC, Sanlley JO, Burkart MD. Protein-protein interface analysis of the non-ribosomal peptide synthetase peptidyl carrier protein and enzymatic domains. Synthetic and Systems Biotechnology. 7: 677-688. PMID 35224236 DOI: 10.1016/j.synbio.2022.02.006 |
0.363 |
|
| 2021 |
Mindrebo JT, Chen A, Kim WE, Re RN, Davis TD, Noel JP, Burkart MD. Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases. Acs Catalysis. 11: 6787-6799. PMID 36187225 DOI: 10.1021/acscatal.1c00745 |
0.692 |
|
| 2021 |
Bartholow TG, Sztain T, Young MA, Davis TD, Abagyan R, Burkart MD. Protein-protein interaction based substrate control in the octanoic acid transferase, LipB. Rsc Chemical Biology. 2: 1466-1473. PMID 34704050 DOI: 10.1039/d1cb00125f |
0.337 |
|
| 2021 |
Sztain T, Bartholow TG, Lee DJ, Casalino L, Mitchell A, Young MA, Wang J, McCammon JA, Burkart MD. Decoding allosteric regulation by the acyl carrier protein. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33846262 DOI: 10.1073/pnas.2025597118 |
0.343 |
|
| 2021 |
Bartholow TG, Sztain T, Patel A, Lee DJ, Young MA, Abagyan R, Burkart MD. Elucidation of transient protein-protein interactions within carrier protein-dependent biosynthesis. Communications Biology. 4: 340. PMID 33727677 DOI: 10.1038/s42003-021-01838-3 |
0.317 |
|
| 2020 |
Ni QZ, Sierra BN, La Clair JJ, Burkart MD. Chemoenzymatic elaboration of the Raper-Mason pathway unravels the structural diversity within eumelanin pigments. Chemical Science. 11: 7836-7841. PMID 34123072 DOI: 10.1039/d0sc02262d |
0.65 |
|
| 2020 |
Hong K, Beld J, Davis TD, Burkart MD, Palenik B. Screening and characterization of polyhydroxyalkanoate granules, and phylogenetic analysis of polyhydroxyalkanoate synthase gene PhaC in cyanobacteria. Journal of Phycology. PMID 33350471 DOI: 10.1111/jpy.13123 |
0.609 |
|
| 2020 |
Misson LE, Mindrebo JT, Davis TD, Patel A, McCammon JA, Noel JP, Burkart MD. Interfacial plasticity facilitates high reaction rate of FAS malonyl-CoA:ACP transacylase, FabD. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929027 DOI: 10.1073/Pnas.2009805117 |
0.61 |
|
| 2020 |
Mindrebo JT, Misson LE, Johnson C, Noel JP, Burkart MD. Activity Mapping the Acyl Carrier Protein - Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis. Biochemistry. PMID 32857494 DOI: 10.1021/Acs.Biochem.0C00605 |
0.611 |
|
| 2020 |
Subramanian R, Suzuki Y, Tallorin L, Sahu S, Thompson MP, Gianneschi NC, Burkart MD, Tezcan FA. Enzyme-Directed Functionalization of Designed, Two-Dimensional Protein Lattices. Biochemistry. PMID 32706243 DOI: 10.1021/Acs.Biochem.0C00363 |
0.814 |
|
| 2020 |
Charov K, Burkart MD. Quantifying protein-protein interactions of the acyl carrier protein with solvatochromic probes. Methods in Enzymology. 638: 321-340. PMID 32416920 DOI: 10.1016/Bs.Mie.2020.03.016 |
0.443 |
|
| 2020 |
Du D, Katsuyama Y, Horiuchi M, Fushinobu S, Chen A, Davis TD, Burkart MD, Ohnishi Y. Structural basis for selectivity in a highly reducing type II polyketide synthase. Nature Chemical Biology. PMID 32367018 DOI: 10.1038/S41589-020-0530-0 |
0.6 |
|
| 2020 |
Mindrebo JT, Patel A, Kim WE, Davis TD, Chen A, Bartholow TG, La Clair JJ, McCammon JA, Noel JP, Burkart MD. Gating mechanism of elongating β-ketoacyl-ACP synthases. Nature Communications. 11: 1727. PMID 32265440 DOI: 10.1038/S41467-020-15455-X |
0.704 |
|
| 2020 |
Trieger KA, La Clair JJ, Burkart MD. Splice Modulation Synergizes Cell Cycle Inhibition. Acs Chemical Biology. PMID 32004428 DOI: 10.1021/Acschembio.9B00833 |
0.301 |
|
| 2020 |
Ni QZ, Sierra BN, Clair JJL, Burkart MD. Chemoenzymatic elaboration of the Raper–Mason pathway unravels the structural diversity within eumelanin pigments Chemical Science. 11: 7836-7841. DOI: 10.1039/D0Sc02262D |
0.677 |
|
| 2020 |
Sztain-Pedone T, Burkart MD, McCammon JA. Effect of Cargo Identity on ACYL Carrier Protein Structure Biophysical Journal. 118: 532a. DOI: 10.1016/J.Bpj.2019.11.2918 |
0.365 |
|
| 2020 |
Patel A, MIndrebo JT, Kim WE, Chen A, Bartholow TG, Davis TD, La Clair JJ, McCammon JA, Noel JP, Burkart MD. A Computational Perspective on the Gating Mechanism of β-Ketoacyl-ACP Synthases Biophysical Journal. 118: 502a. DOI: 10.1016/J.Bpj.2019.11.2771 |
0.626 |
|
| 2020 |
Mindrebo JT, Misson LE, Patel A, Charov K, Noel JP, Burkart MD. The Complete Characterization of a Trapped ACYL Carrier Protein-Ketosynthase Complex Biophysical Journal. 118: 182a-183a. DOI: 10.1016/J.Bpj.2019.11.1114 |
0.565 |
|
| 2020 |
Bartholow TG, Sztain-Pedone T, Patel A, Abagyan R, Burkart MD. Elucidation of Protein-Protein Interactions Throughout E. coli Fatty Acid Biosynthesis Biophysical Journal. 118: 182a. DOI: 10.1016/J.Bpj.2019.11.1110 |
0.384 |
|
| 2019 |
Vickery CR, McCulloch IP, Sonnenschein EC, Beld J, Noel JP, Burkart MD. Dissecting modular synthases through inhibition: A complementary chemical and genetic approach. Bioorganic & Medicinal Chemistry Letters. 126820. PMID 31812466 DOI: 10.1016/J.Bmcl.2019.126820 |
0.801 |
|
| 2019 |
Jaremko MJ, Davis TD, Corpuz JC, Burkart MD. Type II non-ribosomal peptide synthetase proteins: structure, mechanism, and protein-protein interactions. Natural Product Reports. PMID 31593192 DOI: 10.1039/C9Np00047J |
0.445 |
|
| 2019 |
Sztain-Pedone T, Bartholow T, McCammon JA, Burkart MD. Shifting the Hydrolysis Equilibrium of Substrate Loaded Acyl Carrier Proteins. Biochemistry. PMID 31397556 DOI: 10.1021/Acs.Biochem.9B00612 |
0.418 |
|
| 2019 |
Callmann CE, LeGuyader CLM, Burton ST, Thompson MP, Hennis R, Barback C, Henriksen NM, Chan WC, Jaremko MJ, Yang J, Garcia A, Burkart MD, Gilson MK, Momper JD, Bertin PA, et al. Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin. Journal of the American Chemical Society. PMID 31317744 DOI: 10.1021/Jacs.9B04272 |
0.343 |
|
| 2019 |
Charov K, Burkart MD. A single tool to monitor multiple protein-protein interactions of the acyl carrier protein. Acs Infectious Diseases. PMID 31317739 DOI: 10.1021/Acsinfecdis.9B00150 |
0.436 |
|
| 2019 |
Milligan JC, Lee DJ, Jackson DR, Schaub AJ, Beld J, Barajas JF, Hale JJ, Luo R, Burkart MD, Tsai SC. Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nature Chemical Biology. PMID 31209348 DOI: 10.1038/S41589-019-0301-Y |
0.711 |
|
| 2019 |
Sztain T, Patel A, Lee DJ, Davis T, McCammon JA, Burkart MD. One atom matters: modifying the thioester linkage affects structure of the acyl carrier protein. Angewandte Chemie (International Ed. in English). PMID 31140212 DOI: 10.1002/Anie.201903815 |
0.41 |
|
| 2019 |
Davis TD, Michaud JM, Burkart MD. Active site labeling of fatty acid and polyketide acyl-carrier protein transacylases. Organic & Biomolecular Chemistry. PMID 31044196 DOI: 10.1039/C8Ob03229G |
0.434 |
|
| 2019 |
Dodge GJ, Patel A, Jaremko KL, McCammon JA, Smith JL, Burkart MD. Structural and dynamical rationale for fatty acid unsaturation in . Proceedings of the National Academy of Sciences of the United States of America. PMID 30872475 DOI: 10.1073/Pnas.1818686116 |
0.374 |
|
| 2018 |
Tallorin L, Wang J, Kim WE, Sahu S, Kosa NM, Yang P, Thompson M, Gilson MK, Frazier PI, Burkart MD, Gianneschi NC. Discovering de novo peptide substrates for enzymes using machine learning. Nature Communications. 9: 5253. PMID 30531862 DOI: 10.1038/S41467-018-07717-6 |
0.782 |
|
| 2018 |
Chan WC, León B, Krug KA, Patel A, La Clair JJ, Burkart MD. Daedal Facets of Splice Modulator Optimization. Acs Medicinal Chemistry Letters. 9: 1070-1072. PMID 30429946 DOI: 10.1021/Acsmedchemlett.8B00456 |
0.311 |
|
| 2018 |
Konno S, La Clair J, Burkart MD. Trapping the complex molecular machinery of polyketide and fatty acid synthases with tunable silyl-cyanohydrin crosslinkers. Angewandte Chemie (International Ed. in English). PMID 30379389 DOI: 10.1002/Anie.201806865 |
0.46 |
|
| 2018 |
Kim W, Patel A, Hur G, Tufar P, Wuo M, McCammon AJ, Burkart MD. Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases. Chembiochem : a European Journal of Chemical Biology. PMID 30194895 DOI: 10.1002/Cbic.201800439 |
0.737 |
|
| 2018 |
Chen A, Re RN, Burkart MD. Type II fatty acid and polyketide synthases: deciphering protein-protein and protein-substrate interactions. Natural Product Reports. PMID 30046786 DOI: 10.1039/C8Np00040A |
0.665 |
|
| 2018 |
Roulet J, Taton A, Golden JW, Arabolaza A, Burkart MD, Gramajo H. Development of a cyanobacterial heterologous polyketide production platform. Metabolic Engineering. PMID 30036678 DOI: 10.1016/J.Ymben.2018.07.013 |
0.342 |
|
| 2018 |
Davis TD, Kunakom S, Burkart MD, Eustaquio AS. Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-l-Methionine and Analogs. Methods in Enzymology. 604: 367-388. PMID 29779659 DOI: 10.1016/Bs.Mie.2018.02.012 |
0.361 |
|
| 2018 |
Sarria S, Bartholow TG, Verga A, Burkart MD, Peralta-Yahya P. Matching Protein Interfaces for Improved Medium-Chain Fatty Acid Production. Acs Synthetic Biology. PMID 29722970 DOI: 10.1021/Acssynbio.7B00334 |
0.372 |
|
| 2018 |
Vickery CR, Cardenas J, Bowman M, Burkart MD, Da Silva NA, Noel JP. A coupled in vitro/in vivo approach for engineering a heterologous Type III PKS to enhance polyketide biosynthesis in Saccharomyces cerevisiae. Biotechnology and Bioengineering. PMID 29457628 DOI: 10.1002/Bit.26564 |
0.807 |
|
| 2017 |
Finzel K, Beld J, Burkart MD, Charkoudian LK. Utilizing Mechanistic Cross-Linking Technology to Study Protein-Protein Interactions: An Experiment Designed for an Undergraduate Biochemistry Lab. Journal of Chemical Education. 94: 375-379. PMID 29255327 DOI: 10.1021/Acs.Jchemed.6B00453 |
0.701 |
|
| 2017 |
Jaremko MJ, Lee DJ, Patel A, Winslow V, Opella SJ, McCammon JA, Burkart MD. Manipulating protein-protein interactions in NRPS type II PCPs. Biochemistry. PMID 28920687 DOI: 10.1021/Acs.Biochem.7B00884 |
0.396 |
|
| 2017 |
Barajas JF, Shakya G, Moreno G, Rivera H, Jackson DR, Topper CL, Vagstad AL, La Clair JJ, Townsend CA, Burkart MD, Tsai SC. Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484029 DOI: 10.1073/Pnas.1609001114 |
0.342 |
|
| 2017 |
Leon B, Kashyap M, Chan W, Krug K, Castro J, LaClair J, Burkart MD. A Challenging Pie to Splice: Drugging the Spliceosome. Angewandte Chemie (International Ed. in English). PMID 28371109 DOI: 10.1002/Anie.201701065 |
0.625 |
|
| 2017 |
León B, Kashyap MK, Chan WC, Krug KA, Castro JE, La Clair JJ, Burkart MD. Das Spliceosom als Angriffspunkt für Pharmaka Angewandte Chemie. 129: 12218-12230. DOI: 10.1002/Ange.201701065 |
0.578 |
|
| 2016 |
Mindrebo JT, Nartey CM, Seto Y, Burkart MD, Noel JP. Corrigendum to "Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom" [Curr Opin Struct Biol 2016, 41:233-246]. Current Opinion in Structural Biology. PMID 27884574 DOI: 10.1016/J.Sbi.2016.11.008 |
0.481 |
|
| 2016 |
Mindrebo JT, Nartey CM, Seto Y, Burkart MD, Noel JP. Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom. Current Opinion in Structural Biology. 41: 233-246. PMID 27662376 DOI: 10.1016/J.Sbi.2016.08.005 |
0.548 |
|
| 2016 |
Barajas JF, Finzel K, Valentic TR, Shakya G, Gamarra N, Martinez D, Meier JL, Vagstad AL, Newman AG, Townsend CA, Burkart MD, Tsai SC. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain. Angewandte Chemie (International Ed. in English). PMID 27653519 DOI: 10.1002/Anie.201605401 |
0.633 |
|
| 2016 |
Crews LA, Balaian L, Delos Santos NP, Leu HS, Court AC, Lazzari E, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Kulidjian A, Storb R, Morris SR, Ball ED, Burkart MD, et al. RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell. PMID 27570067 DOI: 10.1016/J.Stem.2016.08.003 |
0.689 |
|
| 2016 |
Kumar D, Kashyap MK, La Clair JJ, Villa R, Spaanderman I, Chien S, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Selectivity in Small Molecule Splicing Modulation. Acs Chemical Biology. PMID 27499047 DOI: 10.1021/Acschembio.6B00399 |
0.784 |
|
| 2016 |
Rivera H, Dhar S, La Clair JJ, Tsai SC, Burkart MD. An unusual intramolecular trans-amidation. Tetrahedron. 72: 3605-3608. PMID 27346894 DOI: 10.1016/J.Tet.2016.01.062 |
0.313 |
|
| 2016 |
Koo HJ, Vickery CR, Xu Y, Louie GV, O'Maille PE, Bowman M, Nartey CM, Burkart MD, Noel JP. Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. The Journal of Antibiotics. PMID 27328867 DOI: 10.1038/Ja.2016.68 |
0.794 |
|
| 2016 |
Uranga CC, Beld J, Mrse A, Córdova-Guerrero I, Burkart MD, Hernández-Martínez R. Data from mass spectrometry, NMR spectra, GC-MS of fatty acid esters produced by Lasiodiplodia theobromae. Data in Brief. 8: 31-39. PMID 27274528 DOI: 10.1016/J.Dib.2016.05.003 |
0.655 |
|
| 2016 |
Mc Culloch I, Jaremko M, La Clair J, Burkart MD. Fluorescent mechanism-based probes for aerobic flavin-dependent enzyme activity. Chembiochem : a European Journal of Chemical Biology. PMID 27271974 DOI: 10.1002/Cbic.201600275 |
0.397 |
|
| 2016 |
Vranken C, Fin A, Tufar P, Hofkens J, Burkart MD, Tor Y. Chemoenzymatic synthesis and utilization of a SAM analog with an isomorphic nucleobase. Organic & Biomolecular Chemistry. 14: 6189-92. PMID 27270873 DOI: 10.1039/C6Ob00844E |
0.322 |
|
| 2016 |
Foley TL, Dorjsuren D, Dexheimer TS, Burkart MD, Wight WC, Simeonov A. A Platform to Enable the Pharmacological Profiling of Small Molecules in Gel-Based Electrophoretic Mobility Shift Assays. Journal of Biomolecular Screening. PMID 27269812 DOI: 10.1177/1087057116652895 |
0.724 |
|
| 2016 |
Dhar S, La Clair JJ, León B, Hammons JC, Yu Z, Kashyap MK, Castro JE, Burkart MD. A Carbohydrate-Derived Splice Modulator. Journal of the American Chemical Society. PMID 27058259 DOI: 10.1021/Jacs.5B13427 |
0.648 |
|
| 2016 |
Tallorin L, Finzel K, Nguyen Q, Beld J, La Clair JJ, Burkart MD. Trapping of the Enoyl-Acyl Carrier Protein Reductase • Acyl Carrier Protein Interaction. Journal of the American Chemical Society. PMID 26938266 DOI: 10.1021/Jacs.5B13456 |
0.824 |
|
| 2016 |
Uranga CC, Beld J, Mrse A, Córdova-Guerrero I, Burkart MD, Hernández-Martínez R. Fatty acid esters produced by Lasiodiplodia theobromae function as growth regulators in tobacco seedlings. Biochemical and Biophysical Research Communications. PMID 26926564 DOI: 10.1016/J.Bbrc.2016.02.104 |
0.666 |
|
| 2016 |
Beld J, Abbriano R, Finzel K, Hildebrand M, Burkart MD. Probing fatty acid metabolism in bacteria, cyanobacteria, green microalgae and diatoms with natural and unnatural fatty acids. Molecular Biosystems. PMID 26886879 DOI: 10.1039/C5Mb00804B |
0.675 |
|
| 2016 |
Vickery CR, La Clair JJ, Burkart MD, Noel JP. Harvesting the biosynthetic machineries that cultivate a variety of indispensable plant natural products. Current Opinion in Chemical Biology. 31: 66-73. PMID 26851514 DOI: 10.1016/J.Cbpa.2016.01.008 |
0.797 |
|
| 2016 |
Crews LA, Balaian L, Leu HS, Santos NPD, Court AC, Sadarangani A, Zipeto MA, Clair JJL, Villa R, Morris SR, Storb R, Kulidjian A, Ball ED, Burkart MD, Jamieson CHM. Abstract 915: RNA processing signatures of normal versus malignant progenitor cell aging predict leukemia stem cell sensitivity to RNA splicing modulation Cancer Research. 76: 915-915. DOI: 10.1158/1538-7445.Am2016-915 |
0.68 |
|
| 2016 |
Sonnenschein EC, Pu Y, Beld J, Burkart MD. Phosphopantetheinylation in the green microalgae Chlamydomonas reinhardtii Journal of Applied Phycology. 1-9. DOI: 10.1007/S10811-016-0875-7 |
0.702 |
|
| 2015 |
Moynié L, Hope AG, Finzel K, Schmidberger J, Leckie SM, Schneider G, Burkart MD, Smith AD, Gray DW, Naismith JH. A substrate mimic allows high throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA. Journal of Molecular Biology. PMID 26562505 DOI: 10.1016/J.Jmb.2015.10.027 |
0.458 |
|
| 2015 |
Finzel K, Nguyen C, Jackson DR, Gupta A, Tsai SC, Burkart MD. Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA. Chemistry & Biology. PMID 26526101 DOI: 10.1016/J.Chembiol.2015.09.009 |
0.406 |
|
| 2015 |
Jaremko MJ, Lee DJ, Opella SJ, Burkart MD. Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. Journal of the American Chemical Society. 137: 11546-9. PMID 26340431 DOI: 10.1021/Jacs.5B04525 |
0.377 |
|
| 2015 |
Cahill JF, Darlington TK, Fitzgerald C, Schoepp NG, Beld J, Burkart MD, Prather KA. Online Analysis of Single Cyanobacteria and Algae Cells under Nitrogen-Limited Conditions Using Aerosol Time-of-Flight Mass Spectrometry. Analytical Chemistry. 87: 8039-46. PMID 26237223 DOI: 10.1021/Acs.Analchem.5B02326 |
0.637 |
|
| 2015 |
Ferreira-Camargo LS, Tran M, Beld J, Burkart MD, Mayfield SP. Selenocystamine improves protein accumulation in chloroplasts of eukaryotic green algae. Amb Express. 5: 126. PMID 26137911 DOI: 10.1186/S13568-015-0126-3 |
0.703 |
|
| 2015 |
Kashyap MK, Kumar D, Villa R, La Clair JJ, Benner C, Sasik R, Jones H, Ghia EM, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 100: 945-54. PMID 25862704 DOI: 10.3324/Haematol.2014.122069 |
0.769 |
|
| 2015 |
Finzel K, Lee DJ, Burkart MD. Using modern tools to probe the structure-function relationship of fatty acid synthases. Chembiochem : a European Journal of Chemical Biology. 16: 528-47. PMID 25676190 DOI: 10.1002/Cbic.201402578 |
0.462 |
|
| 2015 |
Konno S, Ishikawa F, Suzuki T, Dohmae N, Burkart MD, Kakeya H. Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases. Chemical Communications (Cambridge, England). 51: 2262-5. PMID 25563804 DOI: 10.1039/C4Cc09412C |
0.367 |
|
| 2015 |
Beld J, Lee DJ, Burkart MD. Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Molecular Biosystems. 11: 38-59. PMID 25360565 DOI: 10.1039/C4Mb00443D |
0.695 |
|
| 2015 |
Lindert S, Tallorin L, Nguyen QG, Burkart MD, McCammon JA. In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors. Journal of Computer-Aided Molecular Design. 29: 79-87. PMID 25344312 DOI: 10.1007/S10822-014-9806-3 |
0.797 |
|
| 2015 |
Crews LA, Balaian L, Leu H, Delos Santos N, Court AC, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Morris S, Storb RF, Kulidjian A, Ball ED, Burkart MD, Jamieson C. RNA Splicing Modulation Impairs Acute Myeloid Leukemia Stem Cell Maintenance Blood. 126: 567-567. DOI: 10.1182/Blood.V126.23.567.567 |
0.699 |
|
| 2014 |
Kosa NM, Pham KM, Burkart MD. Chemoenzymatic exchange of phosphopantetheine on protein and peptide. Chemical Science (Royal Society of Chemistry : 2010). 5: 1179-1186. PMID 26998215 DOI: 10.1039/C3Sc53154F |
0.827 |
|
| 2014 |
Ku TH, Sahu S, Kosa NM, Pham KM, Burkart MD, Gianneschi NC. Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials. Journal of the American Chemical Society. 136: 17378-81. PMID 25468257 DOI: 10.1021/Ja509827S |
0.786 |
|
| 2014 |
Shakya G, Rivera H, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, ... Burkart MD, et al. Modeling linear and cyclic PKS intermediates through atom replacement. Journal of the American Chemical Society. 136: 16792-9. PMID 25406716 DOI: 10.1021/Ja5064857 |
0.387 |
|
| 2014 |
Beld J, Cang H, Burkart MD. Visualizing the chain-flipping mechanism in fatty-acid biosynthesis. Angewandte Chemie (International Ed. in English). 53: 14456-61. PMID 25354391 DOI: 10.1002/Anie.201408576 |
0.693 |
|
| 2014 |
Beld J, Finzel K, Burkart MD. Versatility of acyl-acyl carrier protein synthetases. Chemistry & Biology. 21: 1293-9. PMID 25308274 DOI: 10.1016/J.Chembiol.2014.08.015 |
0.719 |
|
| 2014 |
Tallorin L, Durrant JD, Nguyen QG, McCammon JA, Burkart MD. Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase. Bioorganic & Medicinal Chemistry. 22: 6053-61. PMID 25284249 DOI: 10.1016/J.Bmc.2014.09.002 |
0.812 |
|
| 2014 |
Beld J, Blatti JL, Behnke C, Mendez M, Burkart MD. Evolution of acyl-ACP-thioesterases and β-ketoacyl-ACP-synthases revealed by protein-protein interactions. Journal of Applied Phycology. 26: 1619-1629. PMID 25110394 DOI: 10.1007/S10811-013-0203-4 |
0.815 |
|
| 2014 |
Vickery CR, Kosa NM, Casavant EP, Duan S, Noel JP, Burkart MD. Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of Mycobacteria. Acs Chemical Biology. 9: 1939-44. PMID 24963544 DOI: 10.1021/Cb500263P |
0.785 |
|
| 2014 |
Schoepp NG, Stewart RL, Sun V, Quigley AJ, Mendola D, Mayfield SP, Burkart MD. System and method for research-scale outdoor production of microalgae and cyanobacteria. Bioresource Technology. 166: 273-81. PMID 24926599 DOI: 10.1016/J.Biortech.2014.05.046 |
0.306 |
|
| 2014 |
Rothmann M, Kosa NM, Burkart MD. Resin supported acyl carrier protein labeling strategies. Rsc Advances. 4: 9092-9097. PMID 24818001 DOI: 10.1039/C3Ra47847E |
0.813 |
|
| 2014 |
Foley TL, Rai G, Yasgar A, Daniel T, Baker HL, Attene-Ramos M, Kosa NM, Leister W, Burkart MD, Jadhav A, Simeonov A, Maloney DJ. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. Journal of Medicinal Chemistry. 57: 1063-78. PMID 24450337 DOI: 10.1021/Jm401752P |
0.79 |
|
| 2014 |
Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella SJ, Tsai SC, Burkart MD. Trapping the dynamic acyl carrier protein in fatty acid biosynthesis. Nature. 505: 427-31. PMID 24362570 DOI: 10.1038/Nature12810 |
0.436 |
|
| 2014 |
Beld J, Sonnenschein EC, Vickery CR, Noel JP, Burkart MD. The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life. Natural Product Reports. 31: 61-108. PMID 24292120 DOI: 10.1039/C3Np70054B |
0.805 |
|
| 2014 |
Kosa NM, Foley TL, Burkart MD. Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors. The Journal of Antibiotics. 67: 113-20. PMID 24192555 DOI: 10.1038/Ja.2013.106 |
0.806 |
|
| 2014 |
Kosa NM, Pham KM, Burkart MD. Chemoenzymatic exchange of phosphopantetheine on protein and peptide Chemical Science. 5: 1179-1186. DOI: 10.1039/c3sc53154f |
0.79 |
|
| 2014 |
Bruegger J, Caldara G, Beld J, Burkart MD, Tsai SCS. Polyketide Synthase: Sequence, Structure, and Function Natural Products: Discourse, Diversity, and Design. 219-243. DOI: 10.1002/9781118794623.ch12 |
0.6 |
|
| 2013 |
Thomsen M, Vogensen SB, Buchardt J, Burkart MD, Clausen RP. Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs. Organic & Biomolecular Chemistry. 11: 7606-10. PMID 24100405 DOI: 10.1039/C3Ob41702F |
0.406 |
|
| 2013 |
Nonejuie P, Burkart M, Pogliano K, Pogliano J. Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: 16169-74. PMID 24046367 DOI: 10.1073/Pnas.1311066110 |
0.338 |
|
| 2013 |
Javidpour P, Bruegger J, Srithahan S, Korman TP, Crump MP, Crosby J, Burkart MD, Tsai SC. The determinants of activity and specificity in actinorhodin type II polyketide ketoreductase. Chemistry & Biology. 20: 1225-34. PMID 24035284 DOI: 10.1016/J.Chembiol.2013.07.016 |
0.359 |
|
| 2013 |
Bruegger J, Haushalter RW, Haushalter B, Vagstad AL, Vagstad A, Shakya G, Mih N, Townsend CA, Burkart MD, Tsai SC. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers. Chemistry & Biology. 20: 1135-46. PMID 23993461 DOI: 10.1016/J.Chembiol.2013.07.012 |
0.352 |
|
| 2013 |
Villa R, Kashyap MK, Kumar D, Kipps TJ, Castro JE, La Clair JJ, Burkart MD. Stabilized cyclopropane analogs of the splicing inhibitor FD-895. Journal of Medicinal Chemistry. 56: 6576-82. PMID 23919277 DOI: 10.1021/Jm400861T |
0.79 |
|
| 2013 |
Ishikawa F, Haushalter RW, Lee DJ, Finzel K, Burkart MD. Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase. Journal of the American Chemical Society. 135: 8846-9. PMID 23718183 DOI: 10.1021/Ja4042059 |
0.463 |
|
| 2013 |
Blatti JL, Michaud J, Burkart MD. Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. Current Opinion in Chemical Biology. 17: 496-505. PMID 23683348 DOI: 10.1016/J.Cbpa.2013.04.007 |
0.798 |
|
| 2013 |
Rothmann M, Kang M, Villa R, Ntai I, La Clair JJ, Kelleher NL, Chapman E, Burkart MD. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. 135: 5962-5. PMID 23550886 DOI: 10.1021/Ja400795M |
0.799 |
|
| 2013 |
Stewart C, Vickery CR, Burkart MD, Noel JP. Confluence of structural and chemical biology: plant polyketide synthases as biocatalysts for a bio-based future. Current Opinion in Plant Biology. 16: 365-72. PMID 23481348 DOI: 10.1016/J.Pbi.2013.02.004 |
0.787 |
|
| 2013 |
Rodionova IA, Leyn SA, Burkart MD, Boucher N, Noll KM, Osterman AL, Rodionov DA. Novel inositol catabolic pathway in Thermotoga maritima. Environmental Microbiology. 15: 2254-66. PMID 23441918 DOI: 10.1111/1462-2920.12096 |
0.368 |
|
| 2012 |
Villa R, Mandel AL, Jones BD, La Clair JJ, Burkart MD. Structure of FD-895 revealed through total synthesis. Organic Letters. 14: 5396-9. PMID 23072504 DOI: 10.1021/Ol3023006 |
0.771 |
|
| 2012 |
Blatti JL, Beld J, Behnke CA, Mendez M, Mayfield SP, Burkart MD. Manipulating fatty acid biosynthesis in microalgae for biofuel through protein-protein interactions. Plos One. 7: e42949. PMID 23028438 DOI: 10.1371/Journal.Pone.0042949 |
0.815 |
|
| 2012 |
Kosa NM, Haushalter RW, Smith AR, Burkart MD. Reversible labeling of native and fusion-protein motifs. Nature Methods. 9: 981-4. PMID 22983458 DOI: 10.1038/nmeth.2175 |
0.816 |
|
| 2012 |
Hur GH, Vickery CR, Burkart MD. Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology. Natural Product Reports. 29: 1074-98. PMID 22802156 DOI: 10.1039/C2Np20025B |
0.808 |
|
| 2012 |
van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chemistry & Biology. 19: 559-71. PMID 22633408 DOI: 10.1016/J.Chembiol.2012.03.013 |
0.619 |
|
| 2012 |
Ishikawa F, Haushalter RW, Burkart MD. Dehydratase-specific probes for fatty acid and polyketide synthases. Journal of the American Chemical Society. 134: 769-72. PMID 22188524 DOI: 10.1021/Ja2082334 |
0.411 |
|
| 2012 |
Rothmann M, Niessen S, Haushalter RW, Cravatt BF, Burkart MD. Resin-based investigation of acyl carrier protein interaction networks in Escherichia coli. Bioorganic & Medicinal Chemistry. 20: 667-71. PMID 22104437 DOI: 10.1016/J.Bmc.2011.10.053 |
0.806 |
|
| 2012 |
Kashyap MK, Kumar D, Jones HJ, Schwaederlé M, Ghia EM, Villa R, La Clair JJ, Burkart MD, Kipps TJ, Castro JE. Fd-895 and Pladienolide B Inhibit mRNA Splicing and Induce Apoptosis in Chronic Lymphocytic Leukemia Blood. 120: 3890-3890. DOI: 10.1182/Blood.V120.21.3890.3890 |
0.62 |
|
| 2012 |
Blatti JL, Burkart MD. Releasing stored solar energy within pond scum: Biodiesel from algal lipids Journal of Chemical Education. 89: 239-242. DOI: 10.1021/Ed200098C |
0.768 |
|
| 2011 |
Yu WL, Ansari W, Schoepp NG, Hannon MJ, Mayfield SP, Burkart MD. Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microbial Cell Factories. 10: 91. PMID 22047615 DOI: 10.1186/1475-2859-10-91 |
0.323 |
|
| 2011 |
Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, et al. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America. 108: 8815-20. PMID 21555588 DOI: 10.1073/Pnas.1101137108 |
0.777 |
|
| 2011 |
Haushalter RW, Filipp FV, Ko KS, Yu R, Opella SJ, Burkart MD. Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. Acs Chemical Biology. 6: 413-8. PMID 21268653 DOI: 10.1021/Cb200004K |
0.468 |
|
| 2011 |
Worthington AS, Hur GH, Burkart MD. Activity-guided engineering of natural product carrier proteins. Molecular Biosystems. 7: 365-70. PMID 21184004 DOI: 10.1039/C0Mb00251H |
0.819 |
|
| 2011 |
Meier JL, Burkart MD. Proteomic analysis of polyketide and nonribosomal peptide biosynthesis. Current Opinion in Chemical Biology. 15: 48-56. PMID 21087894 DOI: 10.1016/J.Cbpa.2010.10.021 |
0.634 |
|
| 2011 |
Meier JL, Patel AD, Niessen S, Meehan M, Kersten R, Yang JY, Rothmann M, Cravatt BF, Dorrestein PC, Burkart MD, Bafna V. Practical 4'-phosphopantetheine active site discovery from proteomic samples. Journal of Proteome Research. 10: 320-9. PMID 21067235 DOI: 10.1021/Pr100953B |
0.794 |
|
| 2010 |
Yu WL, Guizzunti G, Foley TL, Burkart MD, La Clair JJ. An optimized immunoaffinity fluorescent method for natural product target elucidation. Journal of Natural Products. 73: 1659-66. PMID 20836515 DOI: 10.1021/Np100371K |
0.708 |
|
| 2010 |
Foley TL, Yasgar A, Garcia CJ, Jadhav A, Simeonov A, Burkart MD. Preparation of FRET reporters to support chemical probe development. Organic & Biomolecular Chemistry. 8: 4601-6. PMID 20725690 DOI: 10.1039/C0Ob00322K |
0.689 |
|
| 2010 |
Meier JL, Haushalter RW, Burkart MD. A mechanism based protein crosslinker for acyl carrier protein dehydratases. Bioorganic & Medicinal Chemistry Letters. 20: 4936-9. PMID 20620055 DOI: 10.1016/J.Bmcl.2010.06.028 |
0.676 |
|
| 2010 |
Worthington AS, Porter DF, Burkart MD. Mechanism-based crosslinking as a gauge for functional interaction of modular synthases. Organic & Biomolecular Chemistry. 8: 1769-72. PMID 20449476 DOI: 10.1039/B925966J |
0.804 |
|
| 2010 |
Yasgar A, Foley TL, Jadhav A, Inglese J, Burkart MD, Simeonov A. A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular Biosystems. 6: 365-75. PMID 20094656 DOI: 10.1039/B913291K |
0.746 |
|
| 2009 |
Foley TL, Young BS, Burkart MD. Phosphopantetheinyl transferase inhibition and secondary metabolism. The Febs Journal. 276: 7134-45. PMID 19895578 DOI: 10.1111/J.1742-4658.2009.07425.X |
0.747 |
|
| 2009 |
Kang M, Jones BD, Mandel AL, Hammons JC, DiPasquale AG, Rheingold AL, La Clair JJ, Burkart MD. Isolation, structure elucidation, and antitumor activity of spirohexenolides A and B. The Journal of Organic Chemistry. 74: 9054-61. PMID 19883063 DOI: 10.1021/Jo901826D |
0.555 |
|
| 2009 |
Lear MJ, Simon O, Foley TL, Burkart MD, Baiga TJ, Noel JP, DiPasquale AG, Rheingold AL, La Clair JJ. Laetirobin from the parasitic growth of Laetiporus sulphureus on Robinia pseudoacacia. Journal of Natural Products. 72: 1980-7. PMID 19842686 DOI: 10.1021/Np9002838 |
0.736 |
|
| 2009 |
Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, Burkart MD. An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. Acs Chemical Biology. 4: 948-57. PMID 19785476 DOI: 10.1021/Cb9002128 |
0.8 |
|
| 2009 |
Foley TL, Burkart MD. A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Analytical Biochemistry. 394: 39-47. PMID 19573516 DOI: 10.1016/J.Ab.2009.06.037 |
0.755 |
|
| 2009 |
Meier JL, Burkart MD. The chemical biology of modular biosynthetic enzymes. Chemical Society Reviews. 38: 2012-45. PMID 19551180 DOI: 10.1039/B805115C |
0.632 |
|
| 2009 |
Meier JL, Burkart MD. Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes. Methods in Enzymology. 458: 219-54. PMID 19374985 DOI: 10.1016/S0076-6879(09)04809-5 |
0.629 |
|
| 2009 |
Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, Burkart MD. Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis. Chemistry & Biology. 16: 372-81. PMID 19345117 DOI: 10.1016/J.Chembiol.2009.02.009 |
0.809 |
|
| 2009 |
Mercer AC, Meier JL, Torpey JW, Burkart MD. In vivo modification of native carrier protein domains. Chembiochem : a European Journal of Chemical Biology. 10: 1091-100. PMID 19308927 DOI: 10.1002/Cbic.200800838 |
0.811 |
|
| 2008 |
Mercer AC, Meier JL, Hur GH, Smith AR, Burkart MD. Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli. Bioorganic & Medicinal Chemistry Letters. 18: 5991-4. PMID 18701278 DOI: 10.1016/J.Bmcl.2008.07.078 |
0.81 |
|
| 2008 |
Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD. Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem : a European Journal of Chemical Biology. 9: 2096-103. PMID 18666307 DOI: 10.1002/Cbic.200800198 |
0.825 |
|
| 2008 |
Meier JL, Barrows-Yano T, Foley TL, Wike CL, Burkart MD. The unusual macrocycle forming thioesterase of mycolactone. Molecular Biosystems. 4: 663-71. PMID 18493665 DOI: 10.1039/B801397G |
0.799 |
|
| 2008 |
Meier JL, Mercer AC, Burkart MD. Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. Journal of the American Chemical Society. 130: 5443-5. PMID 18376827 DOI: 10.1021/Ja711263W |
0.802 |
|
| 2008 |
Haushalter RW, Worthington AS, Hur GH, Burkart MD. An orthogonal purification strategy for isolating crosslinked domains of modular synthases. Bioorganic & Medicinal Chemistry Letters. 18: 3039-42. PMID 18249538 DOI: 10.1016/J.Bmcl.2008.01.026 |
0.813 |
|
| 2008 |
Kapur S, Worthington A, Tang Y, Cane DE, Burkart MD, Khosla C. Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase. Bioorganic & Medicinal Chemistry Letters. 18: 3034-8. PMID 18243693 DOI: 10.1016/J.Bmcl.2008.01.073 |
0.798 |
|
| 2008 |
Najmabadi P, Ko KS, La Clair JJ, Burkart MD. A Method for Fabrication of Polycarbonate-Based Bioactive Platforms Jala - Journal of the Association For Laboratory Automation. 13: 284-288. DOI: 10.1016/J.Jala.2008.07.003 |
0.312 |
|
| 2007 |
Mandel AL, Jones BD, La Clair JJ, Burkart MD. A synthetic entry to pladienolide B and FD-895. Bioorganic & Medicinal Chemistry Letters. 17: 5159-64. PMID 17681759 DOI: 10.1016/J.Bmcl.2007.06.094 |
0.54 |
|
| 2007 |
Mercer AC, Burkart MD. The ubiquitous carrier protein--a window to metabolite biosynthesis. Natural Product Reports. 24: 750-73. PMID 17653358 DOI: 10.1039/B603921A |
0.756 |
|
| 2007 |
Worthington AS, Burkart MD. The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis. Acs Chemical Biology. 2: 152-4. PMID 17373761 DOI: 10.1021/Cb700053G |
0.772 |
|
| 2007 |
Foley TL, Burkart MD. Site-specific protein modification: advances and applications. Current Opinion in Chemical Biology. 11: 12-9. PMID 17189712 DOI: 10.1016/J.Cbpa.2006.11.036 |
0.757 |
|
| 2006 |
Worthington AS, Rivera H, Torpey JW, Alexander MD, Burkart MD. Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. Acs Chemical Biology. 1: 687-91. PMID 17184132 DOI: 10.1021/Cb6003965 |
0.823 |
|
| 2006 |
Meier JL, Mercer AC, Rivera H, Burkart MD. Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. Journal of the American Chemical Society. 128: 12174-84. PMID 16967968 DOI: 10.1021/Ja063217N |
0.798 |
|
| 2006 |
Mercer AC, Burkart MD. Chemical expansion of cofactor activity. Nature Chemical Biology. 2: 8-10. PMID 16408081 DOI: 10.1038/Nchembio0106-8 |
0.681 |
|
| 2006 |
Worthington AS, Burkart MD. One-pot chemo-enzymatic synthesis of reporter-modified proteins. Organic & Biomolecular Chemistry. 4: 44-6. PMID 16357994 DOI: 10.1039/B512735A |
0.805 |
|
| 2005 |
Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate Chemistry. 16: 1352-5. PMID 16287229 DOI: 10.1021/Bc050213J |
0.359 |
|
| 2005 |
Clarke KM, Mercer AC, La Clair JJ, Burkart MD. In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. Journal of the American Chemical Society. 127: 11234-5. PMID 16089439 DOI: 10.1021/Ja052911K |
0.746 |
|
| 2005 |
Mercer AC, La Clair JJ, Burkart MD. Fluorescent multiplex analysis of carrier protein post-translational modification. Chembiochem : a European Journal of Chemical Biology. 6: 1335-7. PMID 15997462 DOI: 10.1002/Cbic.200500051 |
0.71 |
|
| 2005 |
Mercer AC, Burkart MD. Enzyme-assisted antibiotic engineering--the Wright way. Chemistry & Biology. 12: 147-8. PMID 15734642 DOI: 10.1016/J.Chembiol.2005.01.010 |
0.736 |
|
| 2004 |
Mandel AL, La Clair JJ, Burkart MD. Modular synthesis of pantetheine and phosphopantetheine. Organic Letters. 6: 4801-3. PMID 15606070 DOI: 10.1021/Ol048853+ |
0.564 |
|
| 2004 |
Nyffeler PT, Durón SG, Burkart MD, Vincent SP, Wong CH. Selectfluor: mechanistic insight and applications. Angewandte Chemie (International Ed. in English). 44: 192-212. PMID 15578736 DOI: 10.1002/Anie.200400648 |
0.78 |
|
| 2004 |
Merkel AB, Major LL, Errey JC, Burkart MD, Field RA, Walsh CT, Naismith JH. The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. The Journal of Biological Chemistry. 279: 32684-91. PMID 15159413 DOI: 10.1074/Jbc.M404091200 |
0.526 |
|
| 2004 |
La Clair JJ, Foley TL, Schegg TR, Regan CM, Burkart MD. Manipulation of carrier proteins in antibiotic biosynthesis. Chemistry & Biology. 11: 195-201. PMID 15123281 DOI: 10.1016/J.Chembiol.2004.02.010 |
0.772 |
|
| 2004 |
Nyffeler PT, Durón SG, Burkart MD, Vincent SP, Wong C. Selectfluor: Mechanismen und Anwendungen Angewandte Chemie. 117: 196-217. DOI: 10.1002/Ange.200400648 |
0.75 |
|
| 2003 |
Burkart MD. Metabolic engineering--a genetic toolbox for small molecule organic synthesis. Organic & Biomolecular Chemistry. 1: 1-4. PMID 12929378 DOI: 10.1039/B210173D |
0.311 |
|
| 2002 |
Kohli RM, Walsh CT, Burkart MD. Biomimetic synthesis and optimization of cyclic peptide antibiotics. Nature. 418: 658-61. PMID 12167866 DOI: 10.1038/Nature00907 |
0.694 |
|
| 2002 |
Marshall CG, Burkart MD, Meray RK, Walsh CT. Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases. Biochemistry. 41: 8429-37. PMID 12081492 DOI: 10.1021/Bi0202575 |
0.569 |
|
| 2002 |
Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH. Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 58: 1226-8. PMID 12077451 DOI: 10.1107/S0907444902007382 |
0.793 |
|
| 2002 |
Thomas MG, Burkart MD, Walsh CT. Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis. Chemistry & Biology. 9: 171-84. PMID 11880032 DOI: 10.1016/S1074-5521(02)00100-X |
0.641 |
|
| 2001 |
Luo L, Burkart MD, Stachelhaus T, Walsh CT. Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase. Journal of the American Chemical Society. 123: 11208-18. PMID 11697963 DOI: 10.1021/Ja0166646 |
0.466 |
|
| 2001 |
Chen H, Thomas MG, O'Connor SE, Hubbard BK, Burkart MD, Walsh CT. Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics. Biochemistry. 40: 11651-9. PMID 11570865 DOI: 10.1021/Bi0115434 |
0.646 |
|
| 2001 |
Marshall CG, Burkart MD, Keating TA, Walsh CT. Heterocycle formation in vibriobactin biosynthesis: alternative substrate utilization and identification of a condensed intermediate. Biochemistry. 40: 10655-63. PMID 11524010 DOI: 10.1021/Bi010937S |
0.515 |
|
| 2000 |
Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD. Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11942-7. PMID 11035791 DOI: 10.1073/Pnas.210395097 |
0.784 |
|
| 2000 |
Burkart MD, Vincent SP, Düffels A, Murray BW, Ley SV, Wong CH. Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases. Bioorganic & Medicinal Chemistry. 8: 1937-46. PMID 11003139 DOI: 10.1016/S0968-0896(00)00139-5 |
0.467 |
|
| 2000 |
Burkart MD, Izumi M, Chapman E, Lin CH, Wong CH. Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides. The Journal of Organic Chemistry. 65: 5565-74. PMID 10970295 DOI: 10.1021/Jo000266O |
0.593 |
|
| 1999 |
Vincent SP, Burkart MD, Tsai CY, Zhang Z, Wong CH. Electrophilic Fluorination-Nucleophilic Addition Reaction Mediated by Selectfluor: Mechanistic Studies and New Applications. The Journal of Organic Chemistry. 64: 5264-5279. PMID 34237857 DOI: 10.1021/jo990686h |
0.374 |
|
| 1999 |
Burkart MD, Wong CH. A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV. Analytical Biochemistry. 274: 131-7. PMID 10527506 DOI: 10.1006/Abio.1999.4264 |
0.499 |
|
| 1999 |
Burkart MD, Izumi M, Wong CH. Enzymatic Regeneration of 3'-Phosphoadenosine-5'-Phosphosulfate Using Aryl Sulfotransferase for the Preparative Enzymatic Synthesis of Sulfated Carbohydrates. Angewandte Chemie (International Ed. in English). 38: 2747-2750. PMID 10508369 DOI: 10.1002/(Sici)1521-3773(19990917)38:18<2747::Aid-Anie2747>3.0.Co;2-2 |
0.476 |
|
| 1999 |
Burkart MD, Vincent SP, Wong C. An efficient synthesis of CMP-3-fluoroneuraminic acid Chemical Communications. 1525-1526. DOI: 10.1039/A903362I |
0.449 |
|
| 1999 |
Vincent SP, Burkart MD, Tsai CY, Zhang Z, Wong CH. Electrophilic fluorination - Nucleophilic addition reaction mediated by selectfluor: Mechanistic studies and new applications Journal of Organic Chemistry. 64: 5264-5279. DOI: 10.1021/Jo990686H |
0.427 |
|
| 1999 |
Burkart MD, Izumi M, Wong C. Enzymatische Regeneration von 3′-Phosphoadenosin-5′-phosphosulfat mit Aryl-Sulfotransferase zur präparativen enzymatischen Synthese von sulfatierten Kohlenhydraten Angewandte Chemie. 111: 2912-2915. DOI: 10.1002/(Sici)1521-3757(19990917)111:18<2912::Aid-Ange2912>3.0.Co;2-X |
0.378 |
|
| 1997 |
Murray BW, Wittmann V, Burkart MD, Hung SC, Wong CH. Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. Biochemistry. 36: 823-31. PMID 9020780 DOI: 10.1021/Bi962284Z |
0.641 |
|
| 1997 |
Burkart MD, Zhang Z, Hung SC, Wong CH. A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor Journal of the American Chemical Society. 119: 11743-11746. DOI: 10.1021/Ja9723904 |
0.644 |
|
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