Vince Cryns - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Cell Biology, Molecular Biology

35/87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Etheridge T, Damodaran S, Schultz A, Richards KA, Gawdzik J, Yang B, Cryns V, Jarrard DF. Combination therapy with androgen deprivation for hormone sensitive prostate cancer: A new frontier. Asian Journal of Urology. 6: 57-64. PMID 30775249 DOI: 10.1016/J.Ajur.2018.09.001  0.319
2019 Strekalova E, Malin D, Rajanala H, Cryns VL. Preclinical Breast Cancer Models to Investigate Metabolic Priming by Methionine Restriction. Methods in Molecular Biology (Clifton, N.J.). 1866: 61-73. PMID 30725408 DOI: 10.1007/978-1-4939-8796-2_6  0.387
2017 Strekalova E, Malin D, Rajanala H, Cryns VL. Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression. Breast Cancer Research and Treatment. 163: 435-447. PMID 28324269 DOI: 10.1007/s10549-017-4201-0  0.392
2016 Ugolkov A, Gaisina I, Zhang JS, Billadeau DD, White K, Kozikowski A, Jain S, Cristofanilli M, Giles F, O'Halloran T, Cryns VL, Mazar AP. GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Letters. PMID 27424289 DOI: 10.1016/J.Canlet.2016.07.006  0.349
2016 Malin D, Petrovic V, Strekalova E, Sharma B, Cryns VL. αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target. Pharmacology & Therapeutics. PMID 26820756 DOI: 10.1016/j.pharmthera.2016.01.012  0.438
2015 Strekalova E, Malin D, Good DM, Cryns VL. Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2780-91. PMID 25724522 DOI: 10.1158/1078-0432.CCR-14-2792  0.424
2013 Petrovic V, Malin D, Cryns VL. αB-crystallin promotes oncogenic transformation and inhibits caspase activation in cells primed for apoptosis by Rb inactivation. Breast Cancer Research and Treatment. 138: 415-25. PMID 23471649 DOI: 10.1007/s10549-013-2465-6  0.447
2011 Malin D, Chen F, Schiller C, Koblinski J, Cryns VL. Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5005-15. PMID 21653692 DOI: 10.1158/1078-0432.CCR-11-0099  0.378
2011 Toft DJ, Cryns VL. Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies. Molecular Endocrinology (Baltimore, Md.). 25: 199-211. PMID 20861225 DOI: 10.1210/Edrv.31.5.9988  0.359
2010 Oshita SE, Chen F, Kwan T, Yehiely F, Cryns VL. The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway. Breast Cancer Research and Treatment. 124: 307-15. PMID 20087649 DOI: 10.1007/S10549-010-0735-0  0.699
2010 Evans JR, Bosman JD, Brown-Endres L, Yehiely F, Cryns VL. Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73. Breast Cancer Research and Treatment. 122: 159-68. PMID 19777343 DOI: 10.1007/S10549-009-0542-7  0.725
2010 Bosman JD, Yehiely F, Evans JR, Cryns VL. Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer. Breast Cancer Research and Treatment. 119: 63-70. PMID 19205872 DOI: 10.1007/S10549-009-0330-4  0.748
2008 Lu M, Strohecker A, Chen F, Kwan T, Bosman J, Jordan VC, Cryns VL. Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3168-76. PMID 18483385 DOI: 10.1158/1078-0432.Ccr-07-4362  0.718
2008 Strohecker AM, Yehiely F, Chen F, Cryns VL. Caspase cleavage of HER-2 releases a Bad-like cell death effector. The Journal of Biological Chemistry. 283: 18269-82. PMID 18420586 DOI: 10.1074/Jbc.M802156200  0.763
2008 Ivanov O, Chen F, Wiley EL, Keswani A, Diaz LK, Memmel HC, Rademaker A, Gradishar WJ, Morrow M, Khan SA, Cryns VL. alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer. Breast Cancer Research and Treatment. 111: 411-7. PMID 17968656 DOI: 10.1007/s10549-007-9796-0  0.346
2007 Werner ME, Chen F, Moyano JV, Yehiely F, Jones JC, Cryns VL. Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration. The Journal of Biological Chemistry. 282: 5560-9. PMID 17178732 DOI: 10.1074/jbc.M603669200  0.378
2007 Dusek RL, Godsel LM, Chen F, Strohecker AM, Getsios S, Harmon R, Müller EJ, Caldelari R, Cryns VL, Green KJ. Plakoglobin deficiency protects keratinocytes from apoptosis Journal of Investigative Dermatology. 127: 792-801. PMID 17110936 DOI: 10.1038/Sj.Jid.5700615  0.739
2006 Yehiely F, Moyano JV, Evans JR, Nielsen TO, Cryns VL. Deconstructing the molecular portrait of basal-like breast cancer. Trends in Molecular Medicine. 12: 537-44. PMID 17011236 DOI: 10.1016/j.molmed.2006.09.004  0.329
2006 Moyano JV, Evans JR, Chen F, Lu M, Werner ME, Yehiely F, Diaz LK, Turbin D, Karaca G, Wiley E, Nielsen TO, Perou CM, Cryns VL. AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer. The Journal of Clinical Investigation. 116: 261-70. PMID 16395408 DOI: 10.1172/Jci25888  0.41
2006 Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ. The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes Journal of Biological Chemistry. 281: 3614-3624. PMID 16286477 DOI: 10.1074/Jbc.M508258200  0.469
2005 Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Research. 65: 4799-808. PMID 15930300 DOI: 10.1158/0008-5472.Can-04-3319  0.608
2005 Kamradt MC, Lu M, Werner ME, Kwan T, Chen F, Strohecker A, Oshita S, Wilkinson JC, Yu C, Oliver PG, Duckett CS, Buchsbaum DJ, LoBuglio AF, Jordan VC, Cryns VL. The small heat shock protein αB-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3 Journal of Biological Chemistry. 280: 11059-11066. PMID 15653686 DOI: 10.1074/Jbc.M413382200  0.639
2005 Ebert AD, Chen F, He X, Cryns VL, Bohn MC. A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. Experimental Neurology. 191: S80-94. PMID 15629764 DOI: 10.1016/J.Expneurol.2004.08.024  0.319
2005 Lu M, Kwan T, Yu C, Chen F, Freedman B, Schafer JM, Lee EJ, Jameson JL, Jordan VC, Cryns VL. Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. The Journal of Biological Chemistry. 280: 6742-51. PMID 15569667 DOI: 10.1074/jbc.M411519200  0.56
2004 Chen F, Arseven OK, Cryns VL. Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 27542-8. PMID 15087450 DOI: 10.1074/jbc.M400971200  0.504
2003 Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL. Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis. The Journal of Biological Chemistry. 278: 6848-53. PMID 12477713 DOI: 10.1074/jbc.M212021200  0.49
2002 Kamradt MC, Chen F, Sam S, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of Biological Chemistry. 277: 38731-6. PMID 12140279 DOI: 10.1074/jbc.M201770200  0.515
2002 Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL. Caspase proteolysis of the cohesin component RAD21 promotes apoptosis. The Journal of Biological Chemistry. 277: 16775-81. PMID 11875078 DOI: 10.1074/jbc.M201322200  0.448
2001 Byun Y, Chen F, Chang R, Trivedi M, Green KJ, Cryns VL. Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis Cell Death and Differentiation. 8: 443-450. PMID 11423904 DOI: 10.1038/Sj.Cdd.4400840  0.455
2001 Kamradt MC, Chen F, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. The Journal of Biological Chemistry. 276: 16059-63. PMID 11274139 DOI: 10.1074/jbc.C100107200  0.51
1999 Bialik S, Cryns VL, Drincic A, Miyata S, Wollowick AL, Srinivasan A, Kitsis RN. The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes Circulation Research. 85: 403-414. PMID 10473670 DOI: 10.1161/01.Res.85.5.403  0.419
1999 Holly TA, Drincic A, Byun Y, Nakamura S, Harris K, Klocke FJ, Cryns VL. Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo. Journal of Molecular and Cellular Cardiology. 31: 1709-15. PMID 10471354 DOI: 10.1006/jmcc.1999.1006  0.338
1997 Cryns VL, Byun Y, Rana A, Mellor H, Lustig KD, Ghanem L, Parker PJ, Kirschner MW, Yuan J. Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy. The Journal of Biological Chemistry. 272: 29449-53. PMID 9368003 DOI: 10.1074/Jbc.272.47.29449  0.436
1997 Li H, Bergeron L, Cryns V, Pasternack MS, Zhu H, Shi L, Greenberg A, Yuan J. Activation of caspase-2 in apoptosis. The Journal of Biological Chemistry. 272: 21010-7. PMID 9261102 DOI: 10.1074/Jbc.272.34.21010  0.406
1996 Cryns VL, Bergeron L, Zhu H, Li H, Yuan J. Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease. The Journal of Biological Chemistry. 271: 31277-82. PMID 8940132 DOI: 10.1074/Jbc.271.49.31277  0.383
Low-probability matches (unlikely to be authored by this person)
2010 Ahn RW, Chen F, Chen H, Stern ST, Clogston JD, Patri AK, Raja MR, Swindell EP, Parimi V, Cryns VL, O'Halloran TV. A novel nanoparticulate formulation of arsenic trioxide with enhanced therapeutic efficacy in a murine model of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3607-17. PMID 20519360 DOI: 10.1158/1078-0432.Ccr-10-0068  0.297
2008 Cheang M, Voduc D, Turbin D, Cryns V, Nielsen T. AlphaB-crystallin predicts poor breast cancer survival in basal-like tumors European Journal of Cancer Supplements. 6: 60. DOI: 10.1016/S1359-6349(08)70349-5  0.292
2010 Standley SM, Toft DJ, Cheng H, Soukasene S, Chen J, Raja SM, Band V, Band H, Cryns VL, Stupp SI. Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide. Cancer Research. 70: 3020-6. PMID 20354185 DOI: 10.1158/0008-5472.Can-09-3267  0.29
2007 Diaz LK, Cryns VL, Symmans WF, Sneige N. Triple negative breast carcinoma and the basal phenotype: from expression profiling to clinical practice. Advances in Anatomic Pathology. 14: 419-30. PMID 18049131 DOI: 10.1097/PAP.0b013e3181594733  0.288
2020 Chepikova OE, Malin D, Strekalova E, Lukasheva EV, Zamyatnin AA, Cryns VL. Lysine oxidase exposes a dependency on the thioredoxin antioxidant pathway in triple-negative breast cancer cells. Breast Cancer Research and Treatment. PMID 32696316 DOI: 10.1007/s10549-020-05801-4  0.278
2009 Kennecke HF, Voduc D, Leung S, Cryns VL, Perou CM, Nielsen TO, Cheang M. α-basic-crystallin expression in basal-like breast cancer and its association with brain metastasis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 1025. PMID 27961038 DOI: 10.1200/Jco.2009.27.15_Suppl.1025  0.274
2008 Sitterding SM, Wiseman WR, Schiller CL, Luan C, Chen F, Moyano JV, Watkin WG, Wiley EL, Cryns VL, Diaz LK. AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas. Annals of Diagnostic Pathology. 12: 33-40. PMID 18164413 DOI: 10.1016/j.anndiagpath.2007.02.004  0.27
2010 Lee SM, Ahn RW, Chen F, Fought AJ, O'Halloran TV, Cryns VL, Nguyen ST. Biological evaluation of pH-responsive polymer-caged nanobins for breast cancer therapy. Acs Nano. 4: 4971-8. PMID 20738118 DOI: 10.1021/Nn100560P  0.269
2011 Soukasene S, Toft DJ, Moyer TJ, Lu H, Lee HK, Standley SM, Cryns VL, Stupp SI. Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin. Acs Nano. 5: 9113-21. PMID 22044255 DOI: 10.1021/Nn203343Z  0.263
2011 Adamo B, Deal AM, Livasy C, Burrows E, Fritchie K, Blackwell KL, Hamilton EP, Geradts J, Thorne L, Ugolkov A, Miller CR, Ewend MG, Carey LA, Perou CM, Cryns VL, et al. AlphaB-crystallin (aBC) expression in breast cancer brain metastases (BM) and primary breast cancer (pBC) with eventual BM and association with outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2041. PMID 28023795 DOI: 10.1200/Jco.2011.29.15_Suppl.2041  0.26
2012 Toft DJ, Moyer TJ, Standley SM, Ruff Y, Ugolkov A, Stupp SI, Cryns VL. Coassembled cytotoxic and pegylated peptide amphiphiles form filamentous nanostructures with potent antitumor activity in models of breast cancer. Acs Nano. 6: 7956-65. PMID 22928955 DOI: 10.1021/Nn302503S  0.259
2014 Halo TL, McMahon KM, Angeloni NL, Xu Y, Wang W, Chinen AB, Malin D, Strekalova E, Cryns VL, Cheng C, Mirkin CA, Thaxton CS. NanoFlares for the detection, isolation, and culture of live tumor cells from human blood. Proceedings of the National Academy of Sciences of the United States of America. 111: 17104-9. PMID 25404304 DOI: 10.1073/Pnas.1418637111  0.257
2014 Malin D, Strekalova E, Petrovic V, Deal AM, Al Ahmad A, Adamo B, Miller CR, Ugolkov A, Livasy C, Fritchie K, Hamilton E, Blackwell K, Geradts J, Ewend M, Carey L, ... ... Cryns VL, et al. αB-crystallin: a novel regulator of breast cancer metastasis to the brain. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 56-67. PMID 24132917 DOI: 10.1158/1078-0432.Ccr-13-1255  0.256
2011 Su J, Chen F, Cryns VL, Messersmith PB. Catechol polymers for pH-responsive, targeted drug delivery to cancer cells. Journal of the American Chemical Society. 133: 11850-3. PMID 21751810 DOI: 10.1021/ja203077x  0.251
2003 Berry RW, Abraha A, Lagalwar S, LaPointe N, Gamblin TC, Cryns VL, Binder LI. Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment. Biochemistry. 42: 8325-31. PMID 12846581 DOI: 10.1021/Bi027348M  0.24
2000 Lee C, Janulis L, Ilio K, Shah A, Park I, Kim S, Cryns V, Pins M, Bergan R. In vitro models of prostate apoptosis: clusterin as an antiapoptotic mediator. The Prostate. Supplement. 9: 21-4. PMID 11056498 DOI: 10.1002/1097-0045(2000)45:9+<21::Aid-Pros5>3.0.Co;2-C  0.238
2000 Talanian RV, Brady KD, Cryns VL. Caspases as targets for anti-inflammatory and anti-apoptotic drug discovery. Journal of Medicinal Chemistry. 43: 3351-71. PMID 10978183  0.237
2019 Choi S, Chen M, Cryns VL, Anderson RA. A nuclear phosphoinositide kinase complex regulates p53. Nature Cell Biology. PMID 30886346 DOI: 10.1038/s41556-019-0297-2  0.233
2018 Ugolkov AV, Matsangou M, Taxter TJ, O'Halloran TV, Cryns VL, Giles FJ, Mazar AP. Aberrant expression of glycogen synthase kinase-3β in human breast and head and neck cancer. Oncology Letters. 16: 6437-6444. PMID 30405781 DOI: 10.3892/Ol.2018.9483  0.231
1993 Cryns VL, Alexander JM, Klibanski A, Arnold A. The retinoblastoma gene in human pituitary tumors. The Journal of Clinical Endocrinology and Metabolism. 77: 644-6. PMID 7690360 DOI: 10.1210/jcem.77.3.7690360  0.229
2015 Voduc KD, Nielsen TO, Perou CM, Harrell JC, Fan C, Kennecke H, Minn AJ, Cryns VL, Cheang MC. αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis. Npj Breast Cancer. 1. PMID 27656679 DOI: 10.1038/npjbcancer.2015.14  0.222
1994 Cryns VL, Thor A, Xu HJ, Hu SX, Wierman ME, Vickery AL, Benedict WF, Arnold A. Loss of the retinoblastoma tumor-suppressor gene in parathyroid carcinoma. The New England Journal of Medicine. 330: 757-61. PMID 7906387 DOI: 10.1056/NEJM199403173301105  0.218
1994 Cryns VL, Rubio MP, Thor AD, Louis DN, Arnold A. p53 abnormalities in human parathyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. 78: 1320-4. PMID 8200932 DOI: 10.1210/Jcem.78.6.8200932  0.216
1997 Lustig KD, Stukenberg PT, McGarry TJ, King RW, Cryns VL, Mead PE, Zon LI, Yuan J, Kirschner MW. Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. Methods in Enzymology. 283: 83-99. PMID 9251013 DOI: 10.1016/S0076-6879(97)83009-1  0.21
2006 Guillozet-Bongaarts AL, Cahill ME, Cryns VL, Reynolds MR, Berry RW, Binder LI. Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo. Journal of Neurochemistry. 97: 1005-14. PMID 16606369 DOI: 10.1111/J.1471-4159.2006.03784.X  0.189
2019 Moyer TJ, Chen F, Toft DJ, Ruff Y, Cryns VL, Stupp SI. Self-Assembled Peptide Nanostructures Targeting Death Receptor 5 and Encapsulating Paclitaxel As a Multifunctional Cancer Therapy Acs Biomaterials Science & Engineering. 5: 6046-6053. DOI: 10.1021/acsbiomaterials.9b01259  0.189
2015 Malin D, Strekalova E, Petrovic V, Rajanala H, Sharma B, Ugolkov A, Gradishar WJ, Cryns VL. ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo. Oncogene. 34: 5626-34. PMID 25684139 DOI: 10.1038/onc.2015.12  0.182
2020 Bruckbauer ST, Minkoff BB, Yu D, Cryns VL, Cox MM, Sussman MR. Ionizing radiation-induced proteomic oxidation in . Molecular & Cellular Proteomics : McP. PMID 32536603 DOI: 10.1074/Mcp.Ra120.002092  0.182
2019 Strekalova E, Malin D, Weisenhorn EMM, Russell JD, Hoelper D, Jain A, Coon JJ, Lewis PW, Cryns VL. S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability of cancer stem cells. Breast Cancer Research and Treatment. PMID 30712196 DOI: 10.1007/S10549-019-05146-7  0.18
2003 Tsuruta D, Hopkinson SB, Lane KD, Werner ME, Cryns VL, Jones JC. Crucial role of the specificity-determining loop of the integrin beta4 subunit in the binding of cells to laminin-5 and outside-in signal transduction. The Journal of Biological Chemistry. 278: 38707-14. PMID 12867433 DOI: 10.1074/jbc.M301637200  0.18
2020 Chen M, Wen T, Horn HT, Chandrahas VK, Thapa N, Choi S, Cryns VL, Anderson RA. The nuclear phosphoinositide response to stress. Cell Cycle (Georgetown, Tex.). 1-22. PMID 31902273 DOI: 10.1080/15384101.2019.1711316  0.176
2013 Goldberg MS, Hook SS, Wang AZ, Bulte JW, Patri AK, Uckun FM, Cryns VL, Hanes J, Akin D, Hall JB, Gharkholo N, Mumper RJ. Biotargeted nanomedicines for cancer: six tenets before you begin. Nanomedicine (London, England). 8: 299-308. PMID 23394158 DOI: 10.2217/Nnm.13.3  0.17
2011 Antin JH, Emmert-Buck MR, Aplin AE, Cheng SY, Cryns VL, Wang D. Launching of American Journal of Cancer Research. American Journal of Cancer Research. 1: i. PMID 21969259  0.156
2011 Antin JH, Aplin AE, Cheng SY, Emmert-Buck MR, Cryns VL, Wang D. American journal of cancer research: editorial board (2011). American Journal of Cancer Research. 1: 817-22. PMID 22016829  0.155
1995 Cryns VL, Yi SM, Tahara H, Gaz RD, Arnold A. Frequent loss of chromosome arm 1p DNA in parathyroid adenomas. Genes, Chromosomes & Cancer. 13: 9-17. PMID 7541648  0.143
2004 Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI. Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7895-902. PMID 15356202 DOI: 10.1523/Jneurosci.1988-04.2004  0.141
2015 Fernando IR, Ferris DP, Frasconi M, Malin D, Strekalova E, Yilmaz MD, Ambrogio MW, Algaradah MM, Hong MP, Chen X, Nassar MS, Botros YY, Cryns VL, Stoddart JF. Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery. Nanoscale. 7: 7178-83. PMID 25820516 DOI: 10.1039/C4Nr07443B  0.139
1990 St Germain DL, Dittrich W, Morganelli CM, Cryns V. Molecular cloning by hybrid arrest of translation in Xenopus laevis oocytes. Identification of a cDNA encoding the type I iodothyronine 5'-deiodinase from rat liver. The Journal of Biological Chemistry. 265: 20087-90. PMID 1700781  0.139
2003 Gamblin TC, Chen F, Zambrano A, Abraha A, Lagalwar S, Guillozet AL, Lu M, Fu Y, Garcia-Sierra F, LaPointe N, Miller R, Berry RW, Binder LI, Cryns VL. Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 10032-7. PMID 12888622 DOI: 10.1073/Pnas.1630428100  0.131
2017 Richards K, Liou J, Cryns V, Downs T, Abel J, Jarrard D. MP53-08 METFORMIN USE IS ASSOCIATED WITH IMPROVED SURVIVAL IN VETERANS WITH ADVANCED PROSTATE CANCER ON ANDROGEN DEPRIVATION THERAPY Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1659  0.127
2013 Frasconi M, Liu Z, Lei J, Wu Y, Strekalova E, Malin D, Ambrogio MW, Chen X, Botros YY, Cryns VL, Sauvage JP, Stoddart JF. Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles. Journal of the American Chemical Society. 135: 11603-13. PMID 23815127 DOI: 10.1021/Ja405058Y  0.124
2018 Yu D, Yang SE, Miller BR, Wisinski JA, Sherman DS, Brinkman JA, Tomasiewicz JL, Cummings NE, Kimple ME, Cryns VL, Lamming DW. Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701211R. PMID 29401631 DOI: 10.1096/Fj.201701211R  0.112
2014 Moyer TJ, Finbloom JA, Chen F, Toft DJ, Cryns VL, Stupp SI. pH and amphiphilic structure direct supramolecular behavior in biofunctional assemblies. Journal of the American Chemical Society. 136: 14746-52. PMID 25310840 DOI: 10.1021/Ja5042429  0.108
1996 Tahara H, Smith AP, Gas RD, Cryns VL, Arnold A. Genomic localization of novel candidate tumor suppressor gene loci in human parathyroid adenomas. Cancer Research. 56: 599-605. PMID 8564978  0.104
1998 Cryns V, Yuan J. Proteases to die for. Genes & Development. 12: 1551-70. PMID 9620844 DOI: 10.1101/Gad.12.11.1551  0.104
2018 Richards KA, Liou JI, Cryns VL, Downs TM, Abel EJ, Jarrard DF. Metformin Use Is Associated with Improved Survival in Patients with Advanced Prostate Cancer on Androgen Deprivation Therapy. The Journal of Urology. PMID 29940252 DOI: 10.1016/J.Juro.2018.06.031  0.099
2020 Haws SA, Yu D, Ye C, Wille CK, Nguyen LC, Krautkramer KA, Tomasiewicz JL, Yang SE, Miller BR, Liu WH, Igarashi K, Sridharan R, Tu BP, Cryns VL, Lamming DW, et al. Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Molecular Cell. PMID 32208170 DOI: 10.1016/J.Molcel.2020.03.004  0.071
2016 Toft DJ, Fuller M, Schipma M, Chen F, Cryns VL, Layden BT. αB-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance. Genomics Data. 9: 10-7. PMID 27330996 DOI: 10.1016/J.Gdata.2016.03.010  0.07
2016 Toft DJ, Fuller M, Schipma M, Chen F, Cryns VL, Layden BT. αB-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance Genomics Data. 9: 10-17. DOI: 10.1016/j.gdata.2016.03.010  0.07
2000 Abraha A, Ghoshal N, Gamblin TC, Cryns V, Berry RW, Kuret J, Binder LI. C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. Journal of Cell Science. 113: 3737-45. PMID 11034902  0.065
1995 Baron JA, Comi RJ, Cryns V, Brinck-Johnsen T, Mercer NG. The effect of cigarette smoking on adrenal cortical hormones. The Journal of Pharmacology and Experimental Therapeutics. 272: 151-5. PMID 7815328  0.036
2017 Hanseree P, Staples AC, Cryns VL, Hansen KE. Hypocalciuria as a Predictor of Reduced Intestinal Calcium Absorption. Journal of the Endocrine Society. 1: 1179-1187. PMID 29264573 DOI: 10.1210/js.2017-00234  0.03
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