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Tingjian Chen - Publications

Affiliations: 
2011- Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sun L, Xiang Y, Du Y, Wang Y, Ma J, Wang Y, Wang X, Wang G, Chen T. Template-independent synthesis and 3'-end labelling of 2'-modified oligonucleotides with terminal deoxynucleotidyl transferases. Nucleic Acids Research. PMID 39149896 DOI: 10.1093/nar/gkae691  0.413
2024 Wen C, Wang G, Yang L, Chen T, Liu H, Gong W. Structural basis for C2'-methoxy recognition by DNA polymerases and function improvement. Journal of Molecular Biology. 168744. PMID 39147125 DOI: 10.1016/j.jmb.2024.168744  0.443
2024 Wang G, Du Y, Chen T. Enzymatic Preparation of DNA with an Expanded Genetic Alphabet Using Terminal Deoxynucleotidyl Transferase and Its Applications. Methods in Molecular Biology (Clifton, N.J.). 2760: 133-145. PMID 38468086 DOI: 10.1007/978-1-0716-3658-9_8  0.463
2023 Cao Y, Bai J, Zou J, Du Y, Chen T. One-Pot Enzymatic Preparation of Oligonucleotides with an Expanded Genetic Alphabet via Controlled Pause and Restart of Primer Extension: Making Unnatural Out of Natural. Acs Synthetic Biology. 12: 2691-2706. PMID 37672623 DOI: 10.1021/acssynbio.3c00258  0.471
2023 Qin Y, Ma X, Tao R, Du Y, Chen T. Synthesis, Reverse Transcription, Replication, and Inter-Transcription of 2'-Modified Nucleic Acids with Evolved Thermophilic Polymerases: Efforts toward Multidimensional Expansion of the Central Dogma. Acs Synthetic Biology. 12: 2616-2631. PMID 37646406 DOI: 10.1021/acssynbio.3c00213  0.491
2023 Bai J, Zou J, Cao Y, Du Y, Chen T. Recognition of an Unnatural Base Pair by Tool Enzymes from Bacteriophages and Its Application in the Enzymatic Preparation of DNA with an Expanded Genetic Alphabet. Acs Synthetic Biology. 12: 2676-2690. PMID 37590442 DOI: 10.1021/acssynbio.3c00250  0.47
2022 Wang G, Du Y, Ma X, Ye F, Qin Y, Wang Y, Xiang Y, Tao R, Chen T. Thermophilic Nucleic Acid Polymerases and Their Application in Xenobiology. International Journal of Molecular Sciences. 23. PMID 36499296 DOI: 10.3390/ijms232314969  0.473
2022 Wang G, He C, Zou J, Liu J, Du Y, Chen T. Enzymatic Synthesis of DNA with an Expanded Genetic Alphabet Using Terminal Deoxynucleotidyl Transferase. Acs Synthetic Biology. 11: 4142-4155. PMID 36455255 DOI: 10.1021/acssynbio.2c00456  0.424
2022 Sun L, Ma X, Zhang B, Qin Y, Ma J, Du Y, Chen T. From polymerase engineering to semi-synthetic life: artificial expansion of the central dogma. Rsc Chemical Biology. 3: 1173-1197. PMID 36320892 DOI: 10.1039/d2cb00116k  0.36
2022 Guo YY, Zhang R, Huo B, Wang L, Yuan D, Bai J, Wang H, Zhu G, Zhang X, Zhu A, Chen T, Li L. Site-specific unnatural base excision visible light. Chemical Communications (Cambridge, England). PMID 36184910 DOI: 10.1039/d2cc03664a  0.369
2021 Song P, Zhang R, He C, Chen T. Transcription, Reverse Transcription, and Amplification of Backbone-Modified Nucleic Acids with Laboratory-Evolved Thermophilic DNA Polymerases. Current Protocols. 1: e188. PMID 34232574 DOI: 10.1002/cpz1.188  0.52
2020 Shao Q, Chen T, Sheng K, Liu Z, Zhang Z, Romesberg FE. Selection of Aptamers with Large Hydrophobic 2'-Substituents. Journal of the American Chemical Society. PMID 31961667 DOI: 10.1021/Jacs.9B10538  0.8
2017 Liu Z, Chen T, Romesberg FE. Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers. Chemical Science. 8: 8179-8182. PMID 29568464 DOI: 10.1039/C7Sc03747C  0.815
2017 Chen T, Romesberg FE. A Method for the Exponential Synthesis of RNA: Introducing the Polymerase Chain Transcription (PCT) Reaction. Biochemistry. PMID 28930440 DOI: 10.1021/Acs.Biochem.7B00846  0.614
2017 Chen T, Romesberg FE. Enzymatic synthesis, amplification, and application of DNA with a functionalized backbone. Angewandte Chemie (International Ed. in English). PMID 28914996 DOI: 10.1002/Anie.201707367  0.676
2017 Chen T, Romesberg FE. Polymerase Chain Transcription: Exponential Synthesis of RNA and Modified RNA. Journal of the American Chemical Society. PMID 28715205 DOI: 10.1021/Jacs.7B03981  0.694
2017 Thirunavukarasu D, Chen T, Liu Z, Hongdilokkul N, Romesberg FE. Selection of 2'-Fluoro-Modified Aptamers with Optimized Properties. Journal of the American Chemical Society. PMID 28218835 DOI: 10.1021/Jacs.6B13132  0.655
2016 Chen T, Hongdilokkul N, Liu Z, Thirunavukarasu D, Romesberg FE. The expanding world of DNA and RNA. Current Opinion in Chemical Biology. 34: 80-87. PMID 27565457 DOI: 10.1016/J.Cbpa.2016.08.001  0.668
2016 Chen T, Hongdilokkul N, Liu Z, Adhikary R, Tsuen SS, Romesberg FE. Evolution of thermophilic DNA polymerases for the recognition and amplification of C2'-modified DNA. Nature Chemistry. 8: 556-562. PMID 27219699 DOI: 10.1038/Nchem.2493  0.722
2015 Adhikary R, Yu W, Oda M, Walker RC, Chen T, Stanfield RL, Wilson IA, Zimmermann J, Romesberg FE. Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry. 54: 2085-93. PMID 25756188 DOI: 10.1021/Bi501417Q  0.735
2014 Malyshev DA, Dhami K, Lavergne T, Chen T, Dai N, Foster JM, Corrêa IR, Romesberg FE. A semi-synthetic organism with an expanded genetic alphabet. Nature. 509: 385-8. PMID 24805238 DOI: 10.1038/Nature13314  0.77
2014 Chen T, Romesberg FE. Directed polymerase evolution. Febs Letters. 588: 219-29. PMID 24211837 DOI: 10.1016/J.Febslet.2013.10.040  0.663
2009 Chen Y, Li S, Chen T, Hua H, Lin Z. Random dissection to select for protein split sites and its application in protein fragment complementation. Protein Science : a Publication of the Protein Society. 18: 399-409. PMID 19165722 DOI: 10.1002/Pro.42  0.38
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