Donald M. Jerina - Publications

Affiliations: 
NIH (NIAMDD) 
Website:
https://doi.org/10.1093/carcin/bgr185

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH. Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene. Carcinogenesis. 34: 2184-91. PMID 23671133 DOI: 10.1093/Carcin/Bgt164  0.326
2008 Yagi H, Frank H, Seidel A, Jerina DM. Revised assignment of absolute configuration of the cis- and trans-N6-deoxyadenosine adducts at C14 of (+/-)-11beta,12alpha-dihydroxy-13alpha,14alpha-epoxy-11,12,13,14-tetrahydrodibenzo[a,l]pyrene by stereoselective synthesis. Chemical Research in Toxicology. 21: 2379-92. PMID 19053320 DOI: 10.1021/Tx800268F  0.329
2007 Yagi H, Jerina DM. Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts. The Journal of Organic Chemistry. 72: 9983-90. PMID 18047370 DOI: 10.1021/Jo701705C  0.31
2007 Yagi H, Jerina DM. Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine. The Journal of Organic Chemistry. 72: 6037-45. PMID 17608435 DOI: 10.1021/Jo070303C  0.319
2007 Yagi H, Frank H, Seidel A, Jerina DM. Synthesis and absolute configuration of cis- and trans-opened cyclopenta[cd]pyrene 3,4-oxide N2-deoxyguanosine adducts: conversion to phosphoramidites for oligonucleotide synthesis. Chemical Research in Toxicology. 20: 650-61. PMID 17355153 DOI: 10.1021/Tx600286Z  0.335
2007 Iyer PC, Yagi H, Sayer JM, Jerina DM. 3'-H-phosphonate synthesis of chiral benzo[a]pyrene diol epoxide adducts at N(2) of deoxyguanosine in oligonucleotides. Chemical Research in Toxicology. 20: 311-5. PMID 17305411 DOI: 10.1021/Tx600282Y  0.383
2006 Wang B, Sayer JM, Yagi H, Frank H, Seidel A, Jerina DM. Facile interstrand migration of the hydrocarbon moiety of a dibenzo[a,l]pyrene 11,12-diol 13,14-epoxide adduct at N2 of deoxyguanosine in a duplex oligonucleotide. Journal of the American Chemical Society. 128: 10079-84. PMID 16881636 DOI: 10.1021/Ja0608038  0.304
2005 Chiapperino D, Cai M, Sayer JM, Yagi H, Kroth H, Masutani C, Hanaoka F, Jerina DM, Cheh AM. Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. The Journal of Biological Chemistry. 280: 39684-92. PMID 16188888 DOI: 10.1074/Jbc.M508008200  0.34
2004 Doan L, Yagi H, Jerina DM, Whalen DL. Synthesis and hydrolysis of a cis-chlorohydrin derived from a benzo[a]pyrene 7,8-diol 9,10-epoxide. The Journal of Organic Chemistry. 69: 8012-7. PMID 15527284 DOI: 10.1021/Jo040234R  0.332
2004 Karle IL, Yagi H, Sayer JM, Jerina DM. Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1433-8. PMID 14757823 DOI: 10.1073/Pnas.0307305101  0.329
2004 Graziewicz MA, Sayer JM, Jerina DM, Copeland WC. Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine. Nucleic Acids Research. 32: 397-405. PMID 14729924 DOI: 10.1093/Nar/Gkh213  0.31
2003 Yakovleva L, Tian L, Sayer JM, Kalena GP, Kroth H, Jerina DM, Shuman S. Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications. The Journal of Biological Chemistry. 278: 42170-7. PMID 12909623 DOI: 10.1074/Jbc.M308079200  0.314
2003 Volk DE, Thiviyanathan V, Rice JS, Luxon BA, Shah JH, Yagi H, Sayer JM, Yeh HJC, Jerina DM, Gorenstein DG. Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex Biochemistry. 42: 1410-1420. PMID 12578353 DOI: 10.1021/Bi026745U  0.34
2003 Tian L, Sayer JM, Kroth H, Kalena G, Jerina DM, Shuman S. Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove. The Journal of Biological Chemistry. 278: 9905-11. PMID 12524450 DOI: 10.1074/Jbc.M212468200  0.313
2002 Ramos LA, Pontén I, Dipple A, Kumar S, Yagi H, Sayer JM, Kroth H, Kalena G, Jerina DM. Site-specific mutagenesis in Escherichia coli by N2-deoxyguanosine adducts derived from the highly carcinogenic fjord-region benzo[c]phenanthrene 3,4-diol 1,2-epoxides. Chemical Research in Toxicology. 15: 1619-26. PMID 12482245 DOI: 10.1021/Tx020073R  0.312
2002 Doan L, Yagi H, Jerina DM, Whalen DL. Chloride ion catalyzed conformational inversion of carbocation intermediates in the hydrolysis of a benzo[a]pyrene 7,8-diol 9,10-epoxide. Journal of the American Chemical Society. 124: 14382-7. PMID 12452712 DOI: 10.1021/Ja020436+  0.303
2002 Simhadri S, Kramata P, Zajc B, Sayer JM, Jerina DM, Hinkle DC, Wei CS. Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro. Mutation Research. 508: 137-45. PMID 12379469 DOI: 10.1016/S0027-5107(02)00211-7  0.334
2002 Yagi H, Ramesha AR, Kalena G, Sayer JM, Kumar S, Jerina DM. Novel stereoselective control over cis vs trans opening of benzo[c]phenanthrene 3,4-diol 1,2-epoxides by the exocyclic N(2)-amino group of deoxyguanosine in the presence of hexafluoropropan-2-ol. The Journal of Organic Chemistry. 67: 6678-89. PMID 12227797 DOI: 10.1021/Jo020418A  0.335
2002 Chiapperino D, Kroth H, Kramarczuk IH, Sayer JM, Masutani C, Hanaoka F, Jerina DM, Cheh AM. Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. The Journal of Biological Chemistry. 277: 11765-71. PMID 11821420 DOI: 10.1074/Jbc.M112139200  0.343
2002 Sayer JM, Kroth H, Yagi H, Kalena G, Jerina DM, Ramos LA, Dipple A, Pontén I, Goodman MF. Mutational Consequences on Replication of M13 Constructs Containing Isomeric Diol Epoxide Adducts in E. coli Polycyclic Aromatic Compounds. 22: 871-879. DOI: 10.1080/10406630290104022  0.306
2001 Ilankumaran P, Pannell LK, Gebreselassie P, Pilcher AS, Yagi H, Sayer JM, Jerina DM. Patterns of resistance to exonuclease digestion of oligonucleotides containing polycyclic aromatic hydrocarbon diol epoxide adducts at N6 of deoxyadenosine. Chemical Research in Toxicology. 14: 1330-8. PMID 11559050 DOI: 10.1021/Tx010092L  0.344
2001 Ramos LA, Sayer JM, Yagi H, Shah JH, Dipple A, Jerina DM. Effect of benzo-ring hydroxyl groups on site-specific mutagenesis by tetrahydrobenzo[a]pyrene adducts at N(6) of deoxyadenosine. Chemical Research in Toxicology. 14: 1082-9. PMID 11511182 DOI: 10.1021/Tx010076O  0.318
2001 Kumar S, Chang RL, Wood AW, Xie JG, Huang MT, Cui XX, Kole PL, Sikka HC, Balani SK, Conney AH, Jerina DM. Tumorigenicity of racemic and optically pure bay region diol epoxides and other derivatives of the nitrogen heterocycle dibenz[a,h]acridine on mouse skin. Carcinogenesis. 22: 951-5. PMID 11375904 DOI: 10.1093/Carcin/22.6.951  0.312
2001 Pradhan P, Tirumala S, Liu X, Sayer JM, Jerina DM, Yeh HJ. Solution structure of a trans-opened (10S)-dA adduct of (+)-(7S,8R,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a fully complementary DNA duplex: evidence for a major syn conformation. Biochemistry. 40: 5870-81. PMID 11352722 DOI: 10.1021/Bi002896Q  0.308
2001 Pontén I, Waters LS, Sayer JM, Pilcher AS, Dipple A, Jerina DM. Influence of adduct position and sequence length on the ligation of oligonucleotides containing benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts into M13mp7L2. Mutagenesis. 16: 65-9. PMID 11139600 DOI: 10.1093/Mutage/16.1.65  0.301
2001 Jerina DM. From Arene Oxides to Diol Epoxides and DNA Polycyclic Aromatic Compounds. 19: 5-36. DOI: 10.1080/10406630008034720  0.386
2001 Ramesha AR, Kroth H, Jerina DM. Novel trifluoroethanol mediated synthesis of benzo[ a ]pyrene 7,8-diol 9,10-epoxide adducts at the N 2 -position of deoxyguanosine and the N 6 -position of deoxyadenosine Tetrahedron Letters. 42: 1003-1005. DOI: 10.1016/S0040-4039(00)02220-6  0.34
2000 Volk DE, Rice JS, Luxon BA, Yeh HJC, Liang C, Xie G, Sayer JM, Jerina DM, Gorenstein DG. NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex Biochemistry. 39: 14040-14053. PMID 11087351 DOI: 10.1021/Bi001669L  0.312
2000 Chang RL, Wood AW, Kumar S, Lehr RE, Shirai N, Jerina DM, Conney AH. Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice. Carcinogenesis. 21: 1997-2003. PMID 11062160 DOI: 10.1093/Carcin/21.11.1997  0.656
2000 Pommier Y, Laco GS, Kohlhagen G, Sayer JM, Kroth H, Jerina DM. Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine. Proceedings of the National Academy of Sciences of the United States of America. 97: 10739-44. PMID 10995470 DOI: 10.1073/Pnas.190312697  0.33
2000 Vepachedu SR, Ya N, Yagi H, Sayer JM, Jerina DM. Marked differences in base selectivity between DNA and the free nucleotides upon adduct formation from Bay- and Fjord-region diol epoxides. Chemical Research in Toxicology. 13: 883-90. PMID 10995261 DOI: 10.1021/Tx000073W  0.363
2000 Kroth H, Yagi H, Seidel A, Jerina DM. New and highly efficient synthesis of cis- and trans-opened Benzo[a]pyrene 7,8-diol 9,10-epoxide adducts at the exocyclic N(2)-amino group of deoxyguanosine. The Journal of Organic Chemistry. 65: 5558-64. PMID 10970294 DOI: 10.1021/Jo000522X  0.319
2000 Pontén I, Sayer JM, Pilcher AS, Yagi H, Kumar S, Jerina DM, Dipple A. Factors determining mutagenic potential for individual cis and trans opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts. Biochemistry. 39: 4136-44. PMID 10747805 DOI: 10.1021/Bi991719Q  0.34
2000 Pommier Y, Kohlhagen G, Pourquier P, Sayer JM, Kroth H, Jerina DM. Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages. Proceedings of the National Academy of Sciences of the United States of America. 97: 2040-5. PMID 10688881 DOI: 10.1073/Pnas.040397497  0.357
2000 Desai D, Krzeminski J, Lin J, Chadha A, Miyata N, Yagi H, Jerina DM, Amin S. Syntheses and Identification of Benzo[C]Chrysene Metabolites Polycyclic Aromatic Compounds. 16: 255-264. DOI: 10.1080/10406639908020592  0.306
2000 Pontén I, Page JE, Dipple A, Kumar S, Sayer JM, Yagi H, Pilcher A, Jerina DM. Effect of Structure and Sequence on Mutations Induced by Diol Epoxide-DNA Adducts in anE. Coli−M13 Vector System Polycyclic Aromatic Compounds. 21: 63-72. DOI: 10.1080/10406630008028524  0.304
2000 Jerina DM, Sayer JM, Kroth H, Kohlhagen G, Laco GS, Pommier Y. Bay-Region Diol Epoxides of Benzo[a]Pyrene are Stealth Poisons of Topoisomerase I Polycyclic Aromatic Compounds. 21: 53-62. DOI: 10.1080/10406630008028523  0.339
2000 Whalen D, Doan L, Poulose B, Friedman S, Gold A, Sangaiah R, Ramesha AR, Sayer JM, Jerina DM. Mechanisms of Solution Reactions of Cyclo-Penta[cd]Pyrene Oxide and Acenaphthylene Oxide Polycyclic Aromatic Compounds. 21: 43-52. DOI: 10.1080/10406630008028522  0.346
1999 Adams JD, Sayer JM, Chadha A, Shirai N, Lehr RE, Kumar S, Jerina DM. The proximate carcinogen trans-3,4-dihydroxy-3,4-dihydro-dibenz[c,h]acridine is oxidized stereoselectively and regioselectively by cytochrome 1A1, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats. Chemico-Biological Interactions. 122: 117-35. PMID 10528997 DOI: 10.1016/S0009-2797(99)00116-7  0.678
1999 Page JE, Pilcher AS, Yagi H, Sayer JM, Jerina DM, Dipple A. Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts. Chemical Research in Toxicology. 12: 258-63. PMID 10077488 DOI: 10.1021/Tx980244L  0.315
1999 Pontén I, Sayer JM, Pilcher AS, Yagi H, Kumar S, Jerina DM, Dipple A. Sequence context effects on mutational properties of cis-opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts in site-specific mutation studies. Biochemistry. 38: 1144-52. PMID 9894012 DOI: 10.1021/Bi982436L  0.324
1999 Custer L, Zajc B, Sayer JM, Cullinane C, Phillips DR, Cheh AM, Jerina DM, Bohr VA, Mazur SJ. Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence. Biochemistry. 38: 569-81. PMID 9888796 DOI: 10.1021/Bi9813330  0.341
1999 Sayer JM, Shah JH, Liang C, Xie G, Kroth H, Yagi H, Xiaohongliu, Yeh HJC, Jerina DM. Effect of Absolute Configuration on the Optical and NMR Properties of Oligonucleotides Containing Benzo[a]Pyrene Adducts at N 6 of Deoxyadenosine Polycyclic Aromatic Compounds. 17: 95-104. DOI: 10.1080/10406639908020605  0.376
1998 Page JE, Zajc B, Oh-hara T, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Sequence context profoundly influences the mutagenic potency of trans- opened benzo[a]pyrene 7,8-diol 9,10-epoxide - Purine nucleoside adducts in site-specific mutation studies Biochemistry. 37: 9127-9137. PMID 9636059 DOI: 10.1021/Bi980273V  0.571
1998 Pilcher AS, Yagi H, Jerina DM. A Novel Synthetic Method for Cis-Opened Benzo[a]pyrene 7,8-Diol 9,10-Epoxide Adducts at the ExocyclicN6-Amino Group of Deoxyadenosine Journal of the American Chemical Society. 120: 3520-3521. DOI: 10.1021/Ja980176P  0.307
1998 Dress KR, Gooßen LJ, Liu H, Jerina DM, Sharpless KB. Catalytic aminohydroxylation using adenine-derivatives as the nitrogen source Tetrahedron Letters. 39: 7669-7672. DOI: 10.1016/S0040-4039(98)01716-X  0.306
1997 Schwartz JL, Rice JS, Luxon BA, Sayer JM, Xie G, Yeh HJC, Liu X, Jerina DM, Gorenstein DG. Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: Glycosidic rotation from syn to anti at the modified deoxyadenosine Biochemistry. 36: 11069-11076. PMID 9333324 DOI: 10.1021/Bi971306U  0.324
1997 Einolf HJ, Gross MA, Butch ER, Lin J, Amin S, Yagi H, Jerina DM, Baird WM. Selective Recognition of Substituted Chrysene-Diol Epoxide-2-DNA Adducts by Antiserum prepared Against DNA Adducts of Benzo[c]Phenanthrene-Diol Epoxide-2 Polycyclic Aromatic Compounds. 12: 125-138. DOI: 10.1080/10406639708233831  0.301
1997 Boyd DR, Sharma ND, Agarwal R, Resnick SM, Schocken MJ, Gibson DT, Sayer JM, Yagi H, Jerina DM. Bacterial dioxygenase-catalysed dihydroxylation and chemical resolution routes to enantiopure cis-dihydrodiols of chrysene Journal of the Chemical Society - Perkin Transactions 1. 1715-1723. DOI: 10.1039/A606686K  0.33
1996 Agarwal R, Yagi H, Jerina DM, Dipple A. Benzo[c]phenanthrene 3,4-dihydrodiol 1,2-epoxide adducts in native and denatured DNA. Carcinogenesis. 17: 1773-6. PMID 8761442 DOI: 10.1093/Carcin/17.8.1773  0.328
1996 Agarwal R, Canella KA, Yagi H, Jerina DM, Dipple A. Benzo[c]phenanthrene-DNA adducts in mouse epidermis in relation to the tumorigenicities of four configurationally isomeric 3,4-dihydrodiol 1,2-epoxides. Chemical Research in Toxicology. 9: 586-92. PMID 8728502 DOI: 10.1021/Tx950148+  0.322
1996 Page JE, Christner DF, Lakshman MK, Zajc B, Oh-Hara T, Lipinski LJ, Ross HL, Agarwal R, Szeliga J, Yagi H, Sayer JM, Jerina DM, Dipple A. Effects of polycyclic aromatic hydrocarbon adducts with deoxyguanosine and deoxyadenosine in vivo and in vitro Polycyclic Aromatic Compounds. 10: 171-178. DOI: 10.1080/10406639608034694  0.62
1996 Jerina DM, Sayer JM, Yeh HJ, Liu X, Yagi H, Schurter E, Gorenstein D. NMR Conformational Analysis of DNA Duplexes Containing Diol Epoxide Adducts of Polycyclic Aromatic Hydrocarbons Polycyclic Aromatic Compounds. 10: 145-152. DOI: 10.1080/10406639608034691  0.351
1995 Schurter EJ, Yeh HJ, Sayer JM, Lakshman MK, Yagi H, Jerina DM, Gorenstein DG. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Biochemistry. 34: 1364-75. PMID 7827084 DOI: 10.1021/Bi00004A031  0.603
1995 Adams JD, Yagi H, Levin W, Jerina DM. Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats. Chemico-Biological Interactions. 95: 57-77. PMID 7697754 DOI: 10.1016/0009-2797(94)03354-4  0.346
1995 Schurter EJ, Sayer JM, Oh-hara T, Yeh HJ, Yagi H, Luxon BA, Jerina DM, Gorenstein DG. Nuclear magnetic resonance solution structure of an undecanucleotide duplex with a complementary thymidine base opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7R,8S,9R,10S)-7,8-dihydroxy- 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Biochemistry. 34: 9009-20. PMID 7619800 DOI: 10.1021/Bi00028A009  0.321
1995 Lebreton PR, Huang CR, Fernando H, Zajc B, Lakshman MK, Sayer JM, Jerina DM. Multiple fluorescence lifetimes for oligonucleotides containing single, site-specific modifications at guanine and adenine corresponding to trans addition of exocyclic amino groups to (+)-(7R,8S,9S,10R)- and (-)-(7S,8R,9R,10S)-7,8-Dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene Chemical Research in Toxicology. 8: 338-348. PMID 7578919 DOI: 10.1021/Tx00045A004  0.604
1995 Yeh HJ, Sayer JM, Liu X, Altieri AS, Byrd RA, Lakshman MK, Yagi H, Schurter EJ, Gorenstein DG, Jerina DM. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA. Biochemistry. 34: 13570-81. PMID 7577946 DOI: 10.1021/Bi00041A037  0.612
1994 Cheh AM, Yagi H, Jerina DM. Effect of DNA base sequence on the configuration of deoxyadenosine adducts formed by the Fjord region diol epoxide, (+)-(1R,2S,3R,4S)-3,4-dihydroxy-1,2-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene. Biochemistry. 33: 12911-9. PMID 7947697 DOI: 10.1021/Bi00209A023  0.33
1994 Christner DF, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene - deoxyadenosine adducts Biochemistry. 33: 14297-14305. PMID 7524675 DOI: 10.1021/Bi00251A043  0.616
1994 Lakshman MK, Xiao W, Sayer JM, Cheh AM, Jerina DM. Synthesis and assignment of absolute configuration to the N6-deoxyadenosine adducts resulting from cis and trans ring-opening of phenanthrene 9,10-oxide Journal of Organic Chemistry. 59: 1755-1760. DOI: 10.1021/Jo00086A027  0.638
1994 Boyd DR, Davies RJH, Hamilton L, McCullough JJ, Malone JF, Porter HP, Smith A, Carl JM, Sayer JM, Jerina DM. Synthesis and Solvolysis of Acridine 1,2- and 3,4-Oxides: Crystal Structure of Acridine 1,2-Oxide The Journal of Organic Chemistry. 59: 984-990. DOI: 10.1021/Jo00084A013  0.379
1994 Shipley DS, Ross AM, Mohan RS, Whalen DL, Sayer JM, Serve PM, Jerina DM. Solvolysis of (4-Nitrophenoxy)ethylene Oxides The Journal of Organic Chemistry. 59: 977-983. DOI: 10.1021/Jo00084A012  0.366
1993 Chang RL, Battista S, Wong CQ, Kumar S, Kole PL, Sikka HC, Balani SK, Jerina DM, Conney AH, Wood AW. Bacterial and mammalian cell mutagenicity of four optically active bay-region 10,11-diol-8,9-epoxides of the nitrogen heterocycle dibenz[a,h]acridine. Carcinogenesis. 14: 2233-7. PMID 8242848 DOI: 10.1093/Carcin/14.11.2233  0.304
1993 Boyd DR, Sharma ND, Agarwal SK, Gadaginamath GS, O'Kane GA, Jennings WB, Yagi H, Jerina DM. Synthesis and spontaneous racemization of benz[a]anthracene 3,4-oxide: photochemical oxygen-walk rearrangements of arene oxides of benz[a]anthracene and triphenylene to yield oxepines Journal of the Chemical Society-Perkin Transactions 1. 423-429. DOI: 10.1039/P19930000423  0.362
1993 Nashed NT, Rao TVS, Jerina DM. Sterically induced methoxyl migration on acid-catalyzed dehydration of K-region trans-dihydrodiol monomethyl ethers The Journal of Organic Chemistry. 58: 6344-6348. DOI: 10.1021/Jo00075A030  0.335
1993 Nashed NT, Sayer JM, Jerina DM. Acid-catalyzed rearrangement of K-region arene oxides: observation of ketone intermediates and a sterically induced change in rate-determining step Journal of the American Chemical Society. 115: 1723-1730. DOI: 10.1021/Ja00058A016  0.424
1993 Nashed NT, Bax A, Loncharich RJ, Sayer JM, Jerina DM. Methanolysis of K-region arene oxides: comparison between acid-catalyzed and methoxide ion addition reactions Journal of the American Chemical Society. 115: 1711-1722. DOI: 10.1021/Ja00058A015  0.379
1992 Canella KA, Peltonen K, Yagi H, Jerina DM, Dipple A. Identification of individual benzo[c]phenanthrene dihydrodiol epoxide-DNA adducts by the 32P-postlabeling assay. Chemical Research in Toxicology. 5: 685-90. PMID 1446010 DOI: 10.1021/Tx00029A015  0.332
1992 Lakshman MK, Sayer JM, Yagi H, Jerina DM. Synthesis and duplex-forming properties of a nonanucleotide containing an N6-deoxyadenosine adduct of a bay-region diol epoxide Journal of Organic Chemistry. 57: 4585-4590. DOI: 10.1021/Jo00043A012  0.578
1992 Lakshman MK, Sayer JM, Jerina DM. Synthesis and site-specific incorporation of a bay-region cis ring-opened tetrahydro epoxide-deoxyadenosine adduct into a DNA oligomer Journal of Organic Chemistry. 57: 3438-3443. DOI: 10.1021/Jo00038A037  0.634
1992 Kumar S, Kole PL, Balani SK, Jerina DM. Synthesis of enantiomerically pure bay-region 10,11-diol 8,9-epoxide diastereomers of the carcinogen dibenz[a,h]acridine The Journal of Organic Chemistry. 57: 2784-2787. DOI: 10.1021/Jo00036A006  0.335
1992 Haber MT, Nashed NT, Jerina DM. Enantiomeric Composition of Trans-Dihydrodiols Formed from Meso-K-Region Arene Oxides by Microsomal Epoxide Hydrolase Bioorganic & Medicinal Chemistry Letters. 2: 1729-1734. DOI: 10.1016/S0960-894X(00)80465-5  0.402
1992 Zajc B, Lakshman MK, Sayer JM, Jerina DM. Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine Tetrahedron Letters. 33: 3409-3412. DOI: 10.1016/S0040-4039(00)92649-2  0.629
1992 Lakshman MK, Yeh HJC, Yagi H, Jerina DM. Synthesis of deoxyadenosine adducts from the highly carcinogenic fjord region diol epoxide of benzo[c]phenanthrene Tetrahedron Letters. 33: 7121-7124. DOI: 10.1016/S0040-4039(00)60852-3  0.641
1991 Jerina DM, Chadha A, Cheh AM, Schurdak ME, Wood AW, Sayer JM. Covalent bonding of bay-region diol epoxides to nucleic acids. Advances in Experimental Medicine and Biology. 283: 533-53. PMID 2069024 DOI: 10.1007/978-1-4684-5877-0_70  0.324
1991 Thakker DR, Boehlert C, Levin W, Ryan DE, Thomas PE, Yagi H, Jerina DM. Novel stereoselectivity of rat liver cytochrome(s) P450 toward enantiomers of the trans-1,2-dihydrodiol of triphenylene. Archives of Biochemistry and Biophysics. 288: 54-63. PMID 1898024 DOI: 10.1016/0003-9861(91)90164-E  0.322
1991 Sayer JM, Chadha A, Agarwal SK, Yeh HJC, Yagi H, Jerina DM. Covalent nucleoside adducts of benzo[a]pyrene 7,8-diol 9,10-epoxides: structural reinvestigation and characterization of a novel adenosine adduct on the ribose moiety The Journal of Organic Chemistry. 56: 20-29. DOI: 10.1021/Jo00001A007  0.312
1991 Lakshman MK, Sayer JM, Jerina DM. Chemical synthesis of a bay-region polycyclic aromatic hydrocarbon tetrahydroepoxide-deoxyadenosine adduct and its site-specific incorporation into a DNA oligomer Journal of the American Chemical Society. 113: 6589-6594. DOI: 10.1021/Ja00017A034  0.607
1991 Boyd DR, Bushman DR, Davies RH, Dorriy MR, Hamilton L, Jerina DM, Levin W, McCullough JJ, McMordie RS, Malone JF, Porter H. Absolute configurations of the arene oxide, trans-dihydrodiol and cis-dihydeodiol products resulting from metabolism of quinoline at the 5,6-bond Tetrahedron Letters. 32: 2963-2966. DOI: 10.1016/0040-4039(91)80663-Q  0.388
1990 Cheh AM, Yagi H, Jerina DM. Stereoselective release of polycyclic aromatic hydrocarbon-deoxyadenosine adducts from DNA by the 32P postlabeling and deoxyribonuclease I/snake venom phosphodiesterase digestion methods. Chemical Research in Toxicology. 3: 545-50. PMID 1966469 DOI: 10.1021/Tx00018A009  0.332
1990 Agarwal SK, Boyd DR, Davies RJH, Hamilton L, Jerina DM, McCullough JJ, Porter HP. Synthesis of arene oxide and trans-dihydrodiol metabolites of quinoline Journal of the Chemical Society-Perkin Transactions 1. 1969-1974. DOI: 10.1039/P19900001969  0.4
1990 Sayer JM, Lehr RE, Kumar S, Yagi H, Yeh HJC, Holder GM, Duke CC, Silverton JV, Gibson C, Jerina DM. Comparative solvolytic reactivity of bay-region diol epoxides derived from dibenz[a,j]anthracene and dibenzacridines Journal of the American Chemical Society. 112: 1177-1185. DOI: 10.1021/Ja00159A044  0.635
1990 SAYER JM, LEHR RE, KUMAR S, YAGI H, YEH HJC, HOLDER GM, DUKE CC, SILVERTON JV, GIBSON C, JERINA DM. ChemInform Abstract: Comparative Solvolytic Reactivity of Bay-Region Diol Epoxides Derived from Dibenz(a,j)anthracene and Dibenzacridines Cheminform. 21. DOI: 10.1002/CHIN.199019080  0.644
1990 BUSHMAN DR, GROSSMAN SJ, JERINA DM, LEHR RE. ChemInform Abstract: Synthesis of Optically Active Fjord-Region 11,12-Diol 13,14-Epoxides and the K-Region 9,10-Oxide of the Carcinogen Benzo(g)chrysene. Cheminform. 21. DOI: 10.1002/CHIN.199001154  0.651
1989 Rao SN, Lybrand T, Michaud D, Jerina DM, Kollman PA. Molecular mechanics simulations on covalent complexes between polycyclic carcinogens and B-DNA. Carcinogenesis. 10: 27-38. PMID 2910528 DOI: 10.1093/Carcin/10.1.27  0.335
1989 Sayer JM, Whalen DL, Jerina DM. Chemical strategies for the inactivation of bay-region diol epoxides, ultimate carcinogens derived from polycyclic aromatic hydrocarbons. Drug Metabolism Reviews. 20: 155-82. PMID 2680377 DOI: 10.3109/03602538909103534  0.328
1989 Bushman DR, Grossman SJ, Jerina DM, Lehr RE. Synthesis of optically active fjord-region 11,12-diol 13,14-epoxides and the K-region 9,10-oxide of the carcinogen benzo[g]chrysene The Journal of Organic Chemistry. 54: 3533-3544. DOI: 10.1021/Jo00276A009  0.676
1989 Chadha A, Sayer JM, Yeh HJC, Yagi H, Cheh AM, Pannell LK, Jerina DM. Structures of covalent nucleoside adducts formed from adenine, guanine, and cytosine bases of DNA and the optically active bay-region 3,4-diol 1,2-epoxides of dibenz[a,j]anthracene Journal of the American Chemical Society. 111: 5456-5463. DOI: 10.1021/Jo00067A039  0.385
1989 Balani SK, Sayer JM, Jerina DM. Rearrangements on acid-catalyzed dehydration of regioisomeric thiol adducts formed from K-region arene oxides Journal of the American Chemical Society. 111: 3290-3295. DOI: 10.1021/Ja00191A027  0.389
1989 Bushman DR, Sayer JM, Boyd DR, Jerina DM. Solvolysis of the quinoline 5,6- and 7,8-oxides: effect of the ring nitrogen Journal of the American Chemical Society. 111: 2688-2691. DOI: 10.1021/Ja00189A051  0.361
1987 Dipple A, Pigott MA, Agarwal SK, Yagi H, Sayer JM, Jerina DM. Optically active benzo[c]phenanthrene diol epoxides bind extensively to adenine in DNA. Nature. 327: 535-6. PMID 3587368 DOI: 10.1038/327535A0  0.323
1987 van Bladeren PJ, Balani SK, Sayer JM, Thakker DR, Boyd DR, Ryan DE, Thomas PE, Levin W, Jerina DM. Stereoselective formation of benzo(c)phenanthrene (+)-(3S,4R) and (+)-(5S,6R)-oxides by cytochrome P450c in a highly purified and reconstituted system. Biochemical and Biophysical Research Communications. 145: 160-7. PMID 3109408 DOI: 10.1016/0006-291X(87)91301-5  0.385
1987 Boyd DR, Kennedy DA, Malone JF, O'Kane GA, Thakker DT, Yagi H, Jerina DM. Synthesis of triphenylene 1,2-oxide (1,2-epoxy-1,2-dihydrophenylene) and absolute configuration of the trans-1,2-dihydro diol metabolite of triphenylene. Crystal structure of (–)-(1R,2R)-trans-2-bromo-1-menthylxyacetoxy-1,2,3,4-tetrahydrotriphenylene Journal of the Chemical Society-Perkin Transactions 1. 369-375. DOI: 10.1039/P19870000369  0.374
1987 Boyd DR, Agarwal SK, Balani SK, Dunlop R, Gadaginamath GS, O'Kane GA, Sharma ND, Jennings WB, Yagi H, Jerina DM. Preparation of oxepines during direct chemical synthesis and facile oxygen walk reactions of arene oxides: Theoretical predictions and experimental evidence Journal of the Chemical Society, Chemical Communications. 1633-1635. DOI: 10.1039/C39870001633  0.381
1987 Agarwal SK, Sayer JM, Yeh HJC, Pannell LK, Hilton BD, Pigott MA, Dipple A, Yagi H, Jerina DM. Chemical characterization of DNA adducts derived from the configurationally isomeric benzo[c]phenanthrene-3,4-diol 1,2-epoxides Journal of the American Chemical Society. 109: 2497-2504. DOI: 10.1021/Ja00242A040  0.321
1986 Yeh HJC, Balani SK, Yagi H, Greene RME, Sharma ND, Boyd DR, Jerina DM. Use of chiral lanthanide shift reagents in the determination of enantiomer composition and absolute configuration of epoxides and arene oxides The Journal of Organic Chemistry. 51: 5439-5443. DOI: 10.1021/Jo00376A080  0.323
1986 Agarwal SK, Boyd DR, Porter HP, Jennings WB, Grossman SJ, Jerina DM. Arene oxides and trans-dihydrodiols of quinoline Tetrahedron Letters. 27: 4253-4256. DOI: 10.1016/S0040-4039(00)94245-X  0.381
1986 Balani SK, Van Bladeren PJ, Shirai N, Jerina DM. Resolution and absolute configuration of K-region trans dihydrodiols from polycyclic aromatic hydrocarbons The Journal of Organic Chemistry. 51: 1773-1778. DOI: 10.1002/Chin.198645067  0.318
1986 Sayer JM, Van Bladeren PJ, Yeh HJC, Jerina DM. Absolute configuration of benzo[c]phenanthrene 5,6-oxide and other K-region derivatives The Journal of Organic Chemistry. 51: 452-456. DOI: 10.1002/Chin.198634204  0.378
1985 Nashed NT, Michaud DP, Levin W, Jerina DM. Properties of liver microsomal cholesterol 5,6-oxide hydrolase. Archives of Biochemistry and Biophysics. 241: 149-62. PMID 4026314 DOI: 10.1016/0003-9861(85)90371-6  0.345
1985 Balani SK, Yeh HJ, Ryan DE, Thomas PE, Levin W, Jerina DM. Absolute configuration of the 5,6-oxide formed from 7,12-dimethylbenz[a]anthracene by cytochrome P450c. Biochemical and Biophysical Research Communications. 130: 610-6. PMID 3927907 DOI: 10.1016/0006-291X(85)90460-7  0.354
1985 Huang MT, Chang RL, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. Carcinogenesis. 6: 237-42. PMID 3918802 DOI: 10.1093/Carcin/6.2.237  0.308
1985 McManus MJ, Berchtold GA, Jerina DM. Nucleophilic addition of azide ion to benzene oxide: A reinvestigation Journal of the American Chemical Society. 107: 2977-2978. DOI: 10.1021/Ja00296A027  0.311
1985 Michaud DP, Nashed NT, Jerina DM. Stereoselective synthesis and solvolytic behavior of the isomeric 7-dehydrocholesterol 5,6-oxides The Journal of Organic Chemistry. 50: 1835-1840. DOI: 10.1002/Chin.198542337  0.343
1985 Lehr RE, Kumar S, Shirai N, Jerina DM. Synthesis of enantiomerically pure bay-region 3,4-diol 1,2-epoxide diastereomers and other derivatives of the potent carcinogen dibenz[c,h]acridine The Journal of Organic Chemistry. 50: 98-107. DOI: 10.1002/Chin.198522224  0.671
1985 LEHR RE, KUMAR S, SHIRAI N, JERINA DM. ChemInform Abstract: SYNTHESIS OF ENANTIOMERICALLY PURE BAY-REGION 3,4-DIOL 1,2-EPOXIDE DIASTEREOMERS AND OTHER DERIVATIVES OF THE POTENT CARCINOGEN DIBENZ(C,H)ACRIDINE Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198522224  0.648
1984 Halpin RA, Vyas KP, El-Naggar SF, Jerina DM. Metabolism and hepatotoxicity of the naturally occurring benzo[b]pyran precocene I. Chemico-Biological Interactions. 48: 297-315. PMID 6713597 DOI: 10.1016/0009-2797(84)90142-X  0.306
1984 Balani SK, Boyd DR, Greene RME, Jerina DM. Synthesis and thermal racemization of the 3,4-oxide metabolite of benzo[c] phenanthrene Journal of the Chemical Society-Perkin Transactions 1. 15: 1781-1784. DOI: 10.1039/P19840001781  0.392
1983 Ittah Y, Thakker DR, Levin W, Croisy-Delcey M, Ryan DE, Thomas PE, Conney AH, Jerina DM. Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450. Chemico-Biological Interactions. 45: 15-28. PMID 6872097 DOI: 10.1016/0009-2797(83)90039-X  0.3
1983 Levin W, Wood AW, Chang RL, Newman MS, Thakker DR, Conney AH, Jerina DM. The effect of steric strain in the bay-region of polycyclic aromatic hydrocarbons: tumorigenicity of alkyl-substituted benz[a]anthracenes. Cancer Letters. 20: 139-46. PMID 6421476 DOI: 10.1016/0304-3835(83)90042-3  0.316
1983 Michaud DP, Gupta SC, Whalen DL, Sayer JM, Jerina DM. Effects of pH and salt concentration on the hydrolysis of a benzo[alpha]pyrene 7,8-diol-9,10-epoxide catalyzed by DNA and polyadenylic acid. Chemico-Biological Interactions. 44: 41-52. PMID 6406081 DOI: 10.1016/0009-2797(83)90128-X  0.301
1983 Levin W, Michaud DP, Thomas PE, Jerina DM. Distinct rat hepatic microsomal epoxide hydrolases catalyze the hydration of cholesterol 5,6 alpha-oxide and certain xenobiotic alkene and arene oxides. Archives of Biochemistry and Biophysics. 220: 485-94. PMID 6401984 DOI: 10.1016/0003-9861(83)90439-3  0.364
1983 Huang MT, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Carcinogenesis. 4: 1631-7. PMID 6360409 DOI: 10.1093/Carcin/4.12.1631  0.362
1983 van Bladeren P, Jerina D. Facile synthesis of K-region arene oxides Tetrahedron Letters. 24: 4903-4906. DOI: 10.1016/S0040-4039(01)99806-5  0.402
1983 Yagi H, Thakker DR, Ittah Y, Croisy-Delcey M, Jerina DM. Synthesis and assignment of absolute configuration to the trans 3,4-dihydrodiols and 3,4-diol-1,2-epoxides of benzo[c]phenanthrene Tetrahedron Letters. 24: 1349-1352. DOI: 10.1016/S0040-4039(00)81653-6  0.351
1983 Lehr RE, Jerina DM. Aza-polycyclic aromatic hydrocarbon carcinogenicity: predictions of reactivity of tetrahydrobenzo ring epoxide derivatives Tetrahedron Letters. 24: 27-30. DOI: 10.1016/S0040-4039(00)81317-9  0.659
1983 LEHR RE, JERINA DM. ChemInform Abstract: AZA-POLYCYCLIC AROMATIC HYDROCARBON CARCINOGENICITY: PREDICTIONS OF REACTIVITY OF TETRAHYDROBENZO RING EPOXIDE DERIVATIVES Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198319039  0.631
1982 Vyas KP, Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Stereoselective metabolism of the optical isomers of trans-1,2-dihydroxy-1,2-dihydrophenanthrene to bay-region diol epoxides by rat liver microsomes. Chemico-Biological Interactions. 38: 203-13. PMID 7055851 DOI: 10.1016/0009-2797(82)90040-0  0.346
1982 Wood AW, Sayer JM, Newmark HL, Yagi H, Michaud DP, Jerina DM, Conney AH. Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 79: 5122-6. PMID 6813854 DOI: 10.1073/Pnas.79.17.5122  0.324
1982 van Bladeren PJ, Armstrong RN, Cobb D, Thakker DR, Ryan DE, Thomas PE, Sharma ND, Boyd DR, Levin W, Jerina DM. Stereoselective formation of benz[a]anthracene (+)-(5S,6R)-oxide and (+)-(8R,9S)-oxide by a highly purified and reconstituted system containing cytochrome P-450c. Biochemical and Biophysical Research Communications. 106: 602-9. PMID 6809007 DOI: 10.1016/0006-291X(82)91153-6  0.404
1982 Wood AW, Huang MT, Chang RL, Newmark HL, Lehr RE, Yagi H, Sayer JM, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid. Proceedings of the National Academy of Sciences of the United States of America. 79: 5513-7. PMID 6752950 DOI: 10.1073/Pnas.79.18.5513  0.645
1982 Levin W, Wood A, Chang R, Ryan D, Thomas P, Yagi H, Thakker D, Vyas K, Boyd C, Chu SY, Conney A, Jerina D. Oxidative metabolism of polycyclic aromatic hydrocarbons to ultimate carcinogens. Drug Metabolism Reviews. 13: 555-80. PMID 6290166 DOI: 10.3109/03602538209011087  0.358
1982 Yagi H, Jerina DM. Absolute configuration of the trans-9,10-dihydrodiol metabolite of the carcinogen benzo[a]pyrene Journal of the American Chemical Society. 104: 4026-4027. DOI: 10.1021/Ja00378A051  0.324
1982 Gupta SC, Pohl TM, Friedman SL, Whalen DL, Yagi H, Jerina DM. Guanosine 5'-monophosphate-catalyzed hydrolysis of diastereomeric benzo[a]pyrene-7,8-diol 9,10-epoxides Journal of the American Chemical Society. 104: 3101-3104. DOI: 10.1021/Ja00375A026  0.357
1982 Sayer JM, Yagi H, Silverton JV, Friedman SL, Whalen DL, Jerina DM. Conformational effects in the hydrolyses of rigid benzylic epoxides: implications for diol epoxides of polycyclic hydrocarbons Journal of the American Chemical Society. 104: 1972-1978. DOI: 10.1021/Ja00371A029  0.313
1982 Sayer JM, Lehr RE, Whalen DL, Yagi H, Jerina DM. Structure-reactivity indices for the hydrolysis of diol epoxides of polycyclic aromatic hydrocarbons Tetrahedron Letters. 23: 4431-4434. DOI: 10.1016/S0040-4039(00)85620-8  0.64
1982 Yagi H, Vyas KP, Tada M, Thakker DR, Jerina DM. Synthesis of the enantiomeric bay-region diol epoxides of benz[a]anthracene and chrysene Journal of Organic Chemistry. 47: 1110-1117. DOI: 10.1002/Chin.198231185  0.339
1981 Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Regio- and stereoselectivity of hepatic cytochrome P-450 toward polycyclic aromatic hydrocarbon substrates. Advances in Experimental Medicine and Biology. 136: 525-39. PMID 7344478 DOI: 10.1007/978-1-4757-0674-1_39  0.351
1981 Vyas KP, Yagi H, Levin W, Conney AH, Jerina DM. Metabolism of (-)-trans-(3R, 4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes. Biochemical and Biophysical Research Communications. 98: 961-9. PMID 7225135 DOI: 10.1016/0006-291X(81)91204-3  0.322
1981 Jerina DM, Sayer JM, Yagi H, Croisy-Delcey M, Ittah Y, Thakker DR, Wood AW, Chang RL, Levin W, Conney AH. Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene. Advances in Experimental Medicine and Biology. 136: 501-23. PMID 7046379 DOI: 10.1007/978-1-4757-0674-1_38  0.35
1981 Armstrong RN, Levin W, Ryan DE, Thomas PE, Mah HD, Jerina DM. Stereoselectivity of rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide. Biochemical and Biophysical Research Communications. 100: 1077-84. PMID 6791642 DOI: 10.1016/0006-291X(81)91933-1  0.425
1981 Boyd DR, Gadaginamath GS, Sharma ND, Drake AF, Mason SF, Jerina DM. The synthesis of chiral arene oxide metabolites of benz[a]anthracene: Optically active benz[a]anthracene 10,11- and 5,6-oxides Journal of the Chemical Society, Perkin Transactions 1. 2233-2238. DOI: 10.1039/P19810002233  0.384
1981 Boyd DR, Greene RME, Neill JD, Stubbs ME, Yagi H, Jerina DM. Racemization of phenanthrene 3,4-oxide. Absolute stereochemistry of cis- and trans-phenanthrene 3,4-dihydrodiols Journal of the Chemical Society-Perkin Transactions 1. 12: 1477-1482. DOI: 10.1039/P19810001477  0.359
1981 Chao HSI, Berchtold GA, Boyd DR, Dynak JN, Tomaszewski JE, Yagi H, Jerina DM. Migration and retention of deuterium on aromatization of toluene 1,2-oxide and 2,3-oxide to o-cresol Journal of Organic Chemistry. 46: 1948-1950. DOI: 10.1021/Jo00322A051  0.331
1981 Kedzierski B, Thakker DR, Armstrong RN, Jerina DM. absolute configuration of the k-region 4,5-dihydrodiols and 4,5-oxide of benzo[a]pyrene Tetrahedron Letters. 22: 405-408. DOI: 10.1016/0040-4039(81)80111-6  0.398
1981 SAYER JM, YAGI H, CROISY-DELCEY M, JERINA DM. ChemInform Abstract: NOVEL BAY-REGION DIOL EPOXIDES FROM BENZO(C)PHENANTHRENE Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198146197  0.311
1980 MacLeod MC, Levin W, Conney AH, Lehr RE, Mansfield BK, Jerina DM, Selkirk JK. Metabolism of benzo(e)pyrene by rat liver microsomal enzymes. Carcinogenesis. 1: 165-73. PMID 22282997 DOI: 10.1093/Carcin/1.2.165  0.638
1980 Kouri RE, Wood AW, Levin W, Rude TH, Yagi H, Mah HD, Jerina DM, Conney AH. Carcinogenicity of Benzo[a]pyrene and Thirteen of Its Derivatives in C3H/fCum Mice Journal of the National Cancer Institute. 64: 617-623. DOI: 10.1093/Jnci/64.3.617  0.314
1980 Boyd DR, Gadaginamath GS, Kher A, Malone JF, Yagi H, Jerina DM. (+)- and (–)-Benzo[a]pyrene 7,8-oxide : synthesis, absolute stereochemistry, and stereochemical correlation with other mammalian metabolites of benzo[a]pyrene Journal of the Chemical Society-Perkin Transactions 1. 12: 2112-2116. DOI: 10.1039/P19800002112  0.369
1980 Akhtar MN, Boyd DR, Neill JD, Jerina DM. Stereochemical and mechanistic aspects of sulphoxide, epoxide, arene oxide, and phenol formation by photochemical oxygen atom transfer from aza-aromatic N-oxides Journal of the Chemical Society-Perkin Transactions 1. 11: 1693-1699. DOI: 10.1039/P19800001693  0.366
1980 Armstrong RN, Levin W, Jerina DM. Catalytic Properties Of Microsomal And Purified Epoxide Hydrolase Toward K-Region Arene Oxides Microsomes, Drug Oxidations and Chemical Carcinogenesis. 1119-1123. DOI: 10.1016/B978-0-12-187702-6.50094-3  0.368
1980 Boyd DR, Stubbs ME, Thompson NJ, Yeh HJC, Jerina DM, Wasylishen RE. Nitrogen-15 coupling constants: Geminal coupling,2J(15NH), incis- andtrans-aldonitrones and vicinal coupling,3J(15NH), incis-andtrans-ketimines, oxaziridines and nitrones Organic Magnetic Resonance. 14: 528-533. DOI: 10.1002/Mrc.1270140620  0.329
1980 YAGI H, THAKKER DR, LEHR RE, JERINA DM. ChemInform Abstract: BENZO-RING DIOL EPOXIDES OF BENZO(E)PYRENE AND TRIPHENYLENE Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198003247  0.635
1980 LEHR RE, KUMAR S, COHENOUR PT, JERINA DM. ChemInform Abstract: DIHYDRODIOLS AND DIOL EPOXIDES OF DIBENZO(A,I)- AND -(A,H)PYRENE Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198002204  0.603
1979 Dansette PM, DuBois GC, Jerina DM. Continous fluorometric assay of epoxide hydrase activity. Analytical Biochemistry. 97: 340-5. PMID 525797 DOI: 10.1016/0003-2697(79)90083-6  0.633
1979 Chang RL, Wood AW, Levin W, Mah HD, Thakker DR, Jerina DM, Conney AH. Differences in mutagenicity and cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-oxide: a synergistic interaction of enantiomers. Proceedings of the National Academy of Sciences of the United States of America. 76: 4280-4. PMID 388437 DOI: 10.1073/Pnas.76.9.4280  0.363
1979 Wislocki PG, Buening MK, Levin W, Lehr RE, Thakker DR, Jerina DM, Conney AH. Tumorigenicity of the diastereomeric benz[a]anthracene 3,4-diol-1,2-epoxides and the (+)- and (-)-enantiomers of benz[a]anthracene 3,4-dihydrodiol in newborn mice. Journal of the National Cancer Institute. 63: 201-4. PMID 286829 DOI: 10.1093/Jnci/63.1.201  0.634
1979 Akhtar MN, Hamilton JG, Boyd DR, Braunstein A, Seifried HE, Jerina DM. Anthracene 1,2-oxide: synthesis and role in the metabolism of anthracene by mammals. Journal of the Chemical Society-Perkin Transactions 1. 6: 1442-1446. DOI: 10.1039/P19790001442  0.408
1979 Yagi H, Thakker DR, Lehr RE, Jerina DM. Benzo-ring diol epoxides of benzo[e]pyrene and triphenylene Journal of Organic Chemistry. 44: 3439-3442. DOI: 10.1021/Jo01333A047  0.639
1979 Lehr RE, Kumar S, Cohenour PT, Jerina DM. Dihydrodiols and diol epoxides of dibenzo[a,i]-and [a,h]pyrene Tetrahedron Letters. 20: 3819-3822. DOI: 10.1016/S0040-4039(01)95533-9  0.649
1979 Croisy-Delcey M, Ittah Y, Jerina D. Synthesis of benzo[c]phenanthrene dihydrodiols Tetrahedron Letters. 20: 2849-2852. DOI: 10.1016/S0040-4039(01)86432-7  0.338
1979 JERINA DM, THAKKER DR, YAGI DR, LEVIN W, WOOD AW, CONNEY AH. ChemInform Abstract: CARCINOGENICITY OF BENZO(A)PYRENE DERIVATIVES: THE BAY REGION THEORY Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197914385  0.331
1979 LEHR RE, TAYLOR CW, KUMAR S, MAH HD, JERINA DM. ChemInform Abstract: SYNTHESIS OF THE NON-K-REGION AND K-REGION TRANS-DIHYDRODIOLS OF BENZO(E)PYRENE Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197906145  0.623
1978 Rahimtula AD, O'Brien PJ, Seifried HE, Jerina DM. The mechanism of action of cytochrome P-450. Occurrence of the 'NIH shift' during hydroperoxide-dependent aromatic hydroxylations. European Journal of Biochemistry. 89: 133-41. PMID 699902 DOI: 10.1111/J.1432-1033.1978.Tb20905.X  0.388
1978 Dansette PM, Makedonska VB, Jerina DM. Mechanism of catalysis for the hydration of substituted styrene oxides by hepatic epoxide hydrase. Archives of Biochemistry and Biophysics. 187: 290-8. PMID 666312 DOI: 10.1016/0003-9861(78)90037-1  0.622
1978 Jerina DM, Levin W, Thakker DR, Wood AW, Yagi H, Conney AH. Carcinogenicity of benzo[a]pyrene derivatives: The bay region theory Pure and Applied Chemistry. 50: 1033-1044. DOI: 10.1351/Pac197850091033  0.329
1978 Lehr RE, Taylor CW, Kumar S, Mah HD, Jerina DM. Synthesis of the non-K-region and K-region trans-dihydrodiols of benzo[e]pyrene The Journal of Organic Chemistry. 43: 3462-3466. DOI: 10.1021/Jo00412A008  0.649
1978 Boyd DR, Gadaginamath GS, Hamilton R, Yagi H, Jerina DM. Synthesis of (+)- and (−)-benzo[a]pyrene 7,8-oxide Tetrahedron Letters. 19: 2487-2490. DOI: 10.1016/S0040-4039(01)94807-5  0.358
1977 Bresnick E, Stoming TA, Vaught JB, Thakker DR, Jerina DM. Nuclear metabolism of benzo(a)pyrene and of (+/-)-trans-7-8-dihydroxy-7-8,-dihydrobenzo(a)pyrene. Comparative chromatographic analysis of alkylated DNA. Archives of Biochemistry and Biophysics. 183: 31-7. PMID 907356 DOI: 10.1016/0003-9861(77)90415-5  0.324
1977 Yagi H, Akagi H, Thakker DR, Mah HD, Koreeda M, Jerina DM. Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene. Journal of the American Chemical Society. 99: 2358-9. PMID 864141 DOI: 10.1002/Chin.197725111  0.369
1977 Thakker DR, Yagi H, Akagi H, Koreeda M, Lu AH, Levin W, Wood AW, Conney AH, Jerina DM. Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides. Chemico-Biological Interactions. 16: 281-300. PMID 862130 DOI: 10.1016/0009-2797(77)90108-9  0.328
1977 Bresnick E, Mukhtar H, Stoming TA, Dansette PM, Jerina DM. Effect of phenobarbital and 3-methylcholanthrene administration on epoxide hydrase levels in liver microsomes. Biochemical Pharmacology. 26: 891-2. PMID 861055 DOI: 10.1016/0006-2952(77)90406-3  0.538
1977 Kapitulnik J, Levin W, Conney AH, Yagi H, Jerina DM. Benzo[ a ]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[ a ]pyrene in newborn mice Nature. 266: 378-380. PMID 859608 DOI: 10.1038/266378A0  0.351
1977 Yagi H, Thakker DR, Hernandez O, Koreeda M, Jerina DM. Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene. Journal of the American Chemical Society. 99: 1604-11. PMID 839009 DOI: 10.1021/Ja00447A053  0.318
1977 Lehr RE, Jerina DM. Metabolic activations of polycyclic hydrocarbons - Structure-activity relationships Archives of Toxicology. 39: 1-6. PMID 579975 DOI: 10.1007/Bf00343269  0.663
1977 Wood AW, Levin W, Ryan D, Thomas PE, Yagi H, Mah HD, Thakker DR, Jerina DM, Conney AH. High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene. Biochemical and Biophysical Research Communications. 78: 847-54. PMID 334179 DOI: 10.1016/0006-291X(77)90500-9  0.309
1977 Wood AW, Chang RL, Levin W, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Mutagenicity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides Proceedings of the National Academy of Sciences of the United States of America. 74: 2746-2750. PMID 331315 DOI: 10.1073/Pnas.74.7.2746  0.698
1977 Lehr RE, Jerina DM. Relationships of quantum mechanical calculations, relative mutagenicity of benzom anthracene diol epoxides, and “Bay region” concept of aromatic hydrocarbon carcinogenicity Journal of Toxicology and Environmental Health. 2: 1259-1265. PMID 328916 DOI: 10.1080/15287397709529528  0.65
1977 Wood AW, Levin W, Chang RL, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. Proceedings of the National Academy of Sciences of the United States of America. 74: 3176-9. PMID 269381 DOI: 10.1073/Pnas.74.8.3176  0.626
1977 Kapitulnik J, Levin W, Morecki R, Dansette PM, Jerina DM, Conney AH. Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes. Clinical Pharmacology and Therapeutics. 21: 158-65. PMID 65238 DOI: 10.1002/Cpt1977212158  0.619
1977 Tomaszewski JE, Jerina DM, Levin W, Conney AH. A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system. Archives of Biochemistry and Biophysics. 176: 788-98. PMID 10855 DOI: 10.1016/0003-9861(76)90223-X  0.309
1977 Hayakawa T, Myokei Y, Yagi H, Jerina DM. Purification and Some Properties of Glutathione-S-Epoxide Transferase from Guinea Pig Liver Journal of Biochemistry. 82: 407-415. DOI: 10.1093/Oxfordjournals.Jbchem.A131708  0.33
1977 Lindsay Smith JR, Shaw BAJ, Foulkes DM, Jeffrey AM, Jerina DM. Aromatic hydroxylation. Part 6. Oxidation of naphthalene by di-oxygen in the presence of iron(II) salts Journal of the Chemical Society, Perkin Transactions 2. 1583-1589. DOI: 10.1039/P29770001583  0.358
1977 Lehr RE, Schaefer-Ridder M, Jerina DM. Synthesis and properties of the vicinal trans dihydrodiols of anthracene, phenanthrene, and benzo[a]anthracene The Journal of Organic Chemistry. 42: 736-744. DOI: 10.1021/Jo00424A036  0.656
1977 Whalen DL, Ross AM, Dansette PM, Jerina DM. Specific effects of chloride ion in the hydrolysis of a K-region arene oxide Journal of the American Chemical Society. 99: 5672-5676. DOI: 10.1021/Ja00459A024  0.601
1977 Lehr RE, Schaefer-Ridder M, Jerina DM. Synthesis and reactivity of diol epoxides derived from non-K-region trans-dihydrodiols of benzo[a]anthracene Tetrahedron Letters. 18: 539-542. DOI: 10.1016/S0040-4039(01)92688-7  0.68
1977 Ziffer H, Kabuto K, Gibson DT, Kobal VM, Jerina DM. The absolute stereochemistry of several cis-dihydrodiols microbially produced from substituted benzenes Tetrahedron. 33: 2491-2496. DOI: 10.1016/0040-4020(77)80070-7  0.365
1977 WHALEN DL, ROSS AM, DANSETTE PM, JERINA DM. ChemInform Abstract: SPECIFIC EFFECTS OF CHLORIDE ION IN THE HYDROLYSIS OF A K-REGION ARENE OXIDE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197747093  0.564
1977 LEHR RE, SCHAEFER-RIDDER M, JERINA DM. ChemInform Abstract: SYNTHESIS AND REACTIVITY OF DIOL EPOXIDES DERIVED FROM NON-K-REGION TRANS-DIHYDRODIOLS OF BENZO(A)ANTHRACENE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197724212  0.656
1977 Yagi H, Thakker DR, Hernandez O, Koreeda M, Jerina DM. Synthesis And Reactions Of The Highly Mutagenic 7,8‐Diol 9,10‐Epoxides Of The Carcinogen Benzo(A)Pyrene Cheminform. 8. DOI: 10.1002/Chin.197721193  0.302
1976 Levin W, Wood AW, Yagi H, Dansette PM, Jerina DM, Conney AH. Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin. Proceedings of the National Academy of Sciences of the United States of America. 73: 243-7. PMID 1061121 DOI: 10.1073/Pnas.73.1.243  0.62
1976 Boyd DR, Campbell RM, Craig HC, Watson CG, Daly JW, Jerina DM. Mechanism of aromatic hydroxylation in fungi. Evidence for the formation of arene oxides. Journal of the Chemical Society. Perkin Transactions 1. 2438-43. PMID 1033945 DOI: 10.1039/P19760002438  0.531
1976 Jerina DM, Selander H, Yagi H, Wells MC, Davey JF, Mahadevan V, Gibson DT. Dihydrodiols from anthracene and phenanthrene Journal of the American Chemical Society. 98: 5988-5996. PMID 965633 DOI: 10.1002/Chin.197650168  0.304
1976 Wood AW, Levin W, Lu AYH, Ryan D, West SB, Lehr RE, Schaefer-Ridder M, Jerina DM, Conney AH. Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: Evidence for bay region activation of carcinogenic polycyclic hydrocarbons Biochemical and Biophysical Research Communications. 72: 680-686. PMID 791280 DOI: 10.1016/S0006-291X(76)80093-9  0.658
1976 Wislocki PG, Wood AW, Chang RL, Levin W, Yagi H, Hernandez O, Jerina DM, Conney AH. High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene. Biochemical and Biophysical Research Communications. 68: 1006-12. PMID 769789 DOI: 10.1016/0006-291X(76)91246-8  0.311
1976 Yagi H, Holder GM, Dansette PM, Hernandez O, Yeh HJC, LeMahieu RA, Jerina DM. Synthesis and spectral properties of the isomeric hydroxybenzo[a]pyrenes The Journal of Organic Chemistry. 41: 977-985. DOI: 10.1021/Jo00868A017  0.572
1976 Bruice PY, Bruice TC, Yagi H, Jerina DM. Nucleophilic displacement on the arene oxides of phenanthrene Journal of the American Chemical Society. 98: 2973-2981. DOI: 10.1021/Ja00426A049  0.355
1976 Bruice PY, Bruice TC, Dansette PM, Selander HG, Yagi H, Jerina DM. Comparison of the mechanisms of solvolysis and rearrangement of K-region vs. non-K-region arene oxides of phenanthrene. Comparative solvolytic rate constants of K-region and non-K-region arene oxides Journal of the American Chemical Society. 98: 2965-2973. DOI: 10.1021/Ja00426A048  0.598
1976 Yagi H, Jerina D. Additions and Corrections - A General Synthetic Method for Non-K-Region Arene Oxides Journal of the American Chemical Society. 98: 641-641. DOI: 10.1021/Ja00418A607  0.356
1976 Silverton J, Dansette P, Jerina D. Oxidation of 4,5-dihydrobenzo[a]pyrene with osmium tetroxide. Stereochemistry of a substituted K-region diol. Tetrahedron Letters. 17: 1557-1560. DOI: 10.1016/S0040-4039(01)91615-6  0.631
1976 Dansette P, Ziffer H, Jerina D. Optically active 4-substituted cis-1,2-diphenylethylene oxides and related 1,2-diphenylethane diols Tetrahedron. 32: 2071-2074. DOI: 10.1016/0040-4020(76)85110-1  0.629
1976 Yagi H, Dansette P, Jerina DM. Specifically tritiated arene oxides Journal of Labelled Compounds and Radiopharmaceuticals. 12: 127-132. DOI: 10.1002/Jlcr.2580120115  0.64
1976 DANSETTE PM, ZIFFER H, JERINA DM. ChemInform Abstract: OPTICALLY ACTIVE 4-SUBSTITUTED CIS-1,2-DIPHENYLETHYLENE OXIDES AND RELATED 1,2-DIPHENYLETHANE DIOLS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197652206  0.569
1976 BRUICE PY, BRUICE TC, DANSETTE PM, SELANDER HG, YAGI H, JERINA DM. ChemInform Abstract: COMPARISON OF THE MECHANISMS OF SOLVOLYSIS AND REARRANGEMENT OF K-REGION VS. NON-K-REGION ARENE OXIDES OF PHENANTHRENE. COMPARATIVE SOLVOLYTIC RATE CONSTANTS OF K-REGION AND NON-K-REGION ARENE OXIDES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197631079  0.6
1976 YAGI H, HOLDER GM, DANSETTE PM, HERNANDEZ O, YEH HJC, LEMAHIEU RA, JERINA DM. ChemInform Abstract: SYNTHESIS AND SPECTRAL PROPERTIES OF THE ISOMERIC HYDROXYBENZO(A)PYRENES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197626189  0.579
1975 Selander HG, Jerina DM, Daly JW. Metabolism of acetanilide with hepatic microsomes and reconstituted cytochrome monoxygenase systems. Archives of Biochemistry and Biophysics. 164: 241-6. PMID 4429351 DOI: 10.1016/0003-9861(74)90028-9  0.462
1975 Hayakawa T, Udenfriend S, Yagi H, Jerina DM. Substrates and inhibitors of hepatic glutathione-S-epoxide transferase. Archives of Biochemistry and Biophysics. 170: 438-51. PMID 1190775 DOI: 10.1016/0003-9861(75)90139-3  0.381
1975 Gibson DT, Mahadevan V, Jerina DM, Yogi H, Yeh HJ. Oxidation of the carcinogens benzo [a] pyrene and benzo [a] anthracene to dihydrodiols by a bacterium. Science (New York, N.Y.). 189: 295-7. PMID 1145203 DOI: 10.1126/Science.1145203  0.379
1975 Selander HG, Jerina DM, Piccolo DE, Berchtold GA. Letter: SyntheSis of 3- and 4-chlorobenzene oxides. Unexpected trapping results during metabolism of ]14-c[chlorobenzene by hepatic microsomes. Journal of the American Chemical Society. 97: 4428-30. PMID 1141606 DOI: 10.1021/Ja00848A066  0.361
1975 Tomaszewski JE, Jerina DM, Daly JW. Deuterium isotope effects during formation of phenols by hepatic monoxygenases. Evidence for an alternative to arene oxide pathway. Biochemistry. 14: 2024-31. PMID 1125208 DOI: 10.1021/Bi00680A033  0.527
1975 Wood AW, Goode RL, Chang RL, Levin W, Conney AH, Yagi H, Dansette PM, Jerina DM. Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols. Proceedings of the National Academy of Sciences of the United States of America. 72: 3176-80. PMID 1103140 DOI: 10.1073/Pnas.72.8.3176  0.616
1975 Selander HG, Jerina DM, Daly JW. Metobolism of chlorobenzene with hepatic microsomes and solubilized cytochrome P-450 systems. Archives of Biochemistry and Biophysics. 168: 309-21. PMID 806264 DOI: 10.1016/0003-9861(75)90255-6  0.49
1975 Jeffrey AM, Yeh HJ, Jerina DM, Patel TR, Davey JF, Gibson DT. Initial reactions in the oxidation of naphthalene by Pseudomonas putida. Biochemistry. 14: 575-84. PMID 234247 DOI: 10.1021/Bi00674A018  0.348
1975 Akhtar MN, Boyd DR, Thompson NJ, Koreeda M, Gibson DT, Mahadevan V, Jerina DM. Absolute stereochemistry of the dihydroanthracene-cis- and -trans-1,2-diols produced from anthracene by mammals and bacteria Journal of the Chemical Society, Perkin Transactions 1. 2506-2511. DOI: 10.1039/P19750002506  0.313
1975 Smith JRL, Jerina DM, Kaufman S, Milstein S. Aromatic hydroxylation mediated by flavin autoxidation: lack of the NIH shift Journal of the Chemical Society, Chemical Communications. 881-882. DOI: 10.1039/C39750000881  0.334
1975 Yagi H, Jerina DM. General synthetic method for non-K-region arene oxides Journal of the American Chemical Society. 97: 3185-3192. DOI: 10.1021/Ja00844A044  0.353
1975 Moriarty R, Dansette P, Jerina D. Pyrene derivatives oxygenated at both K-regions. Synthesis of a bis-arene oxide. Tetrahedron Letters. 16: 2557-2560. DOI: 10.1016/S0040-4039(00)75177-X  0.635
1975 MORIARTY RM, DANSETTE P, JERINA DM. ChemInform Abstract: PYRENE DERIVATIVES OXYGENATED AT BOTH K-REGIONS, SYNTHESIS OF A BIS-ARENE OXIDE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197543252  0.6
1975 SELANDER HG, JERINA DM, PICCOLO DE, BERCHTOLD GA. ChemInform Abstract: SYNTHESIS OF 3- AND 4-CHLOROBENZENE OXIDES. UNEXPECTED TRAPPING RESULTS DURING METABOLISM OF ((14)C) CHLOROBENZENE BY HEPATIC MICROSOMES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197541207  0.37
1974 Jerina DM, Daly JW. Arene oxides: a new aspect of drug metabolism. Science (New York, N.Y.). 185: 573-82. PMID 4841570 DOI: 10.1126/Science.185.4151.573  0.463
1974 Dansette P, Jerina DM. A facile synthesis of arene oxides at the K regions of polycylic hydrocarbons. Journal of the American Chemical Society. 96: 1224-5. PMID 4816471 DOI: 10.1002/Chin.197417257  0.631
1974 Holder G, Yagi H, Dansette P, Jerina DM, Levin W, Lu AY, Conney AH. Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proceedings of the National Academy of Sciences of the United States of America. 71: 4356-4360. PMID 4530987 DOI: 10.1073/Pnas.71.11.4356  0.614
1974 Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7  0.687
1974 Jeffrey AM, Yeh HJC, Jerina DM, DeMarinis RM, Foster CH, Piccolo DE, Berchtold GA. Stereochemical course in reactions between nucleophiles and arene oxides Journal of the American Chemical Society. 96: 6929-6937. DOI: 10.1021/Ja00829A020  0.342
1974 Bruice PY, Bruice TC, Selander HG, Yagi H, Jerina DM. Comparative mechanisms of reaction of K-region and non-K-region arene oxides of phenanthrene Journal of the American Chemical Society. 96: 6814-6815. DOI: 10.1021/Ja00828A073  0.338
1974 Jerina DM, Witkop B, McIntosh CL, Chapman OL. Photolysis of arene oxides at low temperatures. Oxygen walks and keto tautomers of phenols [14] Journal of the American Chemical Society. 96: 5578-5580. DOI: 10.1021/Ja00824A050  0.307
1974 JERINA DM, DALY JW. ChemInform Abstract: ARENE OXIDES, A NEW ASPECT OF DRUG METABOLISM Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197452267  0.47
1974 BRUICE PY, BRUICE TC, SELANDER HG, YAGI H, JERINA DM. ChemInform Abstract: COMPARATIVE MECHANISMS OF REACTION OF K-REGION AND NON-K-REGION ARENE OXIDES OF PHENANTHRENE Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197452195  0.332
1974 DANSETTE P, JERINA DM. ChemInform Abstract: A FACILE SYNTHESIS OF ARENE OXIDES AT THE K REGIONS OF POLYCYCLIC HYDROCARBONS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197417257  0.599
1973 Ferris JP, Fasco MJ, Stylianopoulou FL, Jerina DM, Daly JW, Jeffrey AM. Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes. Archives of Biochemistry and Biophysics. 156: 97-103. PMID 4730481 DOI: 10.1016/0003-9861(73)90345-7  0.501
1973 Reed DJ, Vimmerstedt J, Jerina DM, Daly JW. Formation of phenols from aromatic subtrates by plant and animal mono-oxygenases: The effect of adjacent deuteriums on the magnitude of the NIH shift of tritium Archives of Biochemistry and Biophysics. 154: 642-647. PMID 4691507 DOI: 10.1016/0003-9861(73)90019-2  0.501
1973 Oesch F, Jerina DM, Daly JW, Lu AY, Kuntzman R, Conney AH. A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. Archives of Biochemistry and Biophysics. 153: 62-7. PMID 4650623 DOI: 10.1016/0003-9861(72)90420-1  0.497
1973 Oesch F, Jerina DM, Daly JW, Rice JM. Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase Chemico-Biological Interactions. 6: 189-202. PMID 4632460 DOI: 10.1016/0009-2797(73)90071-9  0.518
1973 Kasperek GJ, Bruice PY, Bruice TC, Yagi H, Jerina DM. Multiple pathways for aromatization of 8,9-indan oxide Journal of the American Chemical Society. 95: 6041-6046. DOI: 10.1021/Ja00799A035  0.333
1973 Yagi H, Jerina DM. Synthesis of non-K-region arene oxides Journal of the American Chemical Society. 95: 243-244. DOI: 10.1021/Ja00782A046  0.381
1973 Kasperek GJ, Bruice PY, Bruice TC, Yagi H, Jerina DM. Multiple Pathways For Aromatization Of 8,9-Indan Oxide Cheminform. 4. DOI: 10.1002/Chin.197345267  0.333
1973 Jerina DM, Yagi H, Daly JW. Arene Oxides‐Oxepins Cheminform. 16: 197-282. DOI: 10.1002/9780470187203.Ch2  0.437
1972 Jerina DM, Kaubisch N, Daly JW. Arene oxides as intermediates in the metabolism of aromatic substrates: alkyl and oxygen migrations during isomerization of alkylated arene oxides. Proceedings of the National Academy of Sciences of the United States of America. 68: 2545-8. PMID 5289888 DOI: 10.1073/Pnas.68.10.2545  0.532
1972 Oesch F, Kaubisch N, Jerina DM, Daly JW. Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors. Biochemistry. 10: 4858-66. PMID 5134533 DOI: 10.1021/Bi00802A005  0.407
1972 Oesch F, Jerina DM, Daly JW. Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes. Archives of Biochemistry and Biophysics. 144: 253-61. PMID 5117530 DOI: 10.1016/0003-9861(71)90476-0  0.519
1972 Kaubisch N, Daly JW, Jerina DM. Arene oxides as intermediates in the oxidative metabolism of aromatic compounds. Isomerization of methyl-substituted arene oxides. Biochemistry. 11: 3080-8. PMID 5041913 DOI: 10.1021/Bi00766A022  0.528
1972 Boyd DR, Daly JW, Jerina DM. Rearrangement of (1- 2 H)- and (2- 2 H)naphthalene 1,2-oxides to 1-naphthol. Mechanism of the NIH shift. Biochemistry. 11: 1961-6. PMID 5025637 DOI: 10.1021/Bi00760A035  0.464
1972 Yagi H, Jerina DM, Kasperek GJ, Bruice TC. A novel mechanism for the NIH-shift. Proceedings of the National Academy of Sciences of the United States of America. 69: 1985-6. PMID 4505677 DOI: 10.1073/Pnas.69.7.1985  0.311
1972 Daly JW, Jerina DM, Witkop B. Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds. Experientia. 28: 1129-49. PMID 4117670 DOI: 10.1007/Bf01946135  0.498
1972 Cannon JF, Daly J, Silverton JV, Boyd DR, Jerina DM. Crystal and molecular structure of cis-2-isopropyl-3-(4-nitrophenyl)-oxaziridine Journal of the Chemical Society-Perkin Transactions 1. 1137-1140. DOI: 10.1039/P29720001137  0.432
1972 Kasperek GJ, Bruice TC, Yagi H, Jerina DM. Differentiation between the concerted and stepwise mechanisms for aromatization (NIH-shift) of arene epoxides Journal of the Chemical Society, Chemical Communications. 784-785. DOI: 10.1039/C39720000784  0.308
1972 Kasperek G, Bruice T, Yagi H, Kaubsich N, Jerina D. Solvolytic Chemistry of 1,4-Dimethylbenzene Oxide. A New and Novel Mechanism for the NIH Shift Journal of the American Chemical Society. 94: 7876-7882. DOI: 10.1021/Ja00777A606  0.326
1972 CANNON JF, DALY J, SILVERTON JV, BOYD DR, JERINA DM. ChemInform Abstract: KRISTALL- UND MOLEKULARSTRUKTUR VON CIS-2-ISOPROPYL-3-(4-NITRO-PHENYL)-OXAZIRIDIN Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197239096  0.453
1971 Jerina DM, Daly JW, Jeffrey AM, Gibson DT. Cis-1,2-dihydroxy-1,2-dihydronaphthalene: a bacterial metabolite from naphthalene. Archives of Biochemistry and Biophysics. 142: 394-6. PMID 5545490 DOI: 10.1016/0003-9861(71)90298-0  0.44
1971 Jerina DM, Daly JW, Witkop B. Migration of substituents during Hydroxylation of aromatic substrates (NIH shift). Oxidations with peroxytrifluoroacetic acid. Biochemistry. 10: 366-72. PMID 5543961 DOI: 10.1021/Bi00779A002  0.509
1971 Oesch E, Jerina DM, Daly J. A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide. Biochimica Et Biophysica Acta. 227: 685-91. PMID 4328054 DOI: 10.1016/0005-2744(71)90017-9  0.467
1970 Daly JW, Jerina DM. Aerobic aromatic hydroxylation catalyzed by horseradish peroxidase: absense of NIH shift. Biochimica Et Biophysica Acta. 208: 340-2. PMID 5420986 DOI: 10.1016/0304-4165(70)90256-4  0.428
1970 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. 1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. Biochemistry. 9: 147-56. PMID 5411205 DOI: 10.1021/Bi00803A019  0.521
1970 Daly JW, Jerina DM, Ziffer H, Witkop B, Klärner FG, Vogel E. Enzymatic hydration of 8,9-indan oxide, Homoallylic addition of water. Journal of the American Chemical Society. 92: 702-3. PMID 5411062 DOI: 10.1021/ja00706a048  0.38
1970 Boyd DR, Jerina DM, Daly JW. Optically active 1,2-naphthalene oxide The Journal of Organic Chemistry. 35: 3170-3172. DOI: 10.1021/Jo00834A076  0.46
1970 Jerina DM, Ziffer H, Daly JW. Role of the arene oxide-oxepin system in the metabolism of aromatic substrates. IV. Stereochemical considerations of dihydrodiol formation and dehyrogenation Journal of the American Chemical Society. 92: 1056-1061. DOI: 10.1021/Ja00707A052  0.506
1970 Jerina DM, Boyd DR, Daly JW. Photolysis of pyridine-N-oxide: an oxygen atom transfer model for enzymatic oxygenation, arene oxide formation, and the NIH shift Tetrahedron Letters. 11: 457-460. DOI: 10.1016/0040-4039(70)80074-0  0.475
1970 BOYD DR, JERINA DM, DALY JW. ChemInform Abstract: OPTISCH AKTIVES 1,2-NAPHTHALIN-OXID Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197049305  0.497
1970 JERINA DM, BOYD DR, DALY JW. ChemInform Abstract: PHOTOLYSE VON PYRIDIN-N-OXID, MODELL FUER DIE TRANSFER-RK. VON SAUERSTOFF BEI ENZYMRK., DIE BLDG. VON AREN-OXIDEN SOWIE DIE ′NIH-SHIFTS′ Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197019210  0.466
1969 Daly J, Jerina D, Farnsworth J, Guroff G. The migration of deuterium during aryl hydroxylation. II. Effect of induction of microsomal hydroxylases with phenobarbital or polycyclic aromatic hydrocarbons. Archives of Biochemistry and Biophysics. 131: 238-44. PMID 5781725 DOI: 10.1016/0003-9861(69)90127-1  0.452
1969 Daly J, Jerina D. Migration of deuterium during aryl hydroxylation. 3. Effect of ortho- and meta- substituents. Archives of Biochemistry and Biophysics. 134: 266-8. PMID 5345594 DOI: 10.1016/0003-9861(69)90280-X  0.46
1968 Daly J, Jerina D, Witkop B. Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes. I. Influence of ring substitutents. Archives of Biochemistry and Biophysics. 128: 517-27. PMID 5698035 DOI: 10.1016/0003-9861(68)90059-3  0.458
1968 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. Journal of the American Chemical Society. 90: 6525-7. PMID 5682453 DOI: 10.1021/Ja01025A058  0.507
1968 Jerina DM, Daly JW, Witkop B. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. II. Synthesis of 3,4-toluene-4-2H oxide and subsequent "NIH shift" to 4-hydroxytoluene-3-2H. Journal of the American Chemical Society. 90: 6523-5. PMID 5682452 DOI: 10.1021/Ja01025A057  0.508
1968 Jerina D, Guroff G, Daly J. Enzymic and nonenzymic hydroxylation and chlorination of p-deuteroanisole. Archives of Biochemistry and Biophysics. 124: 612-5. PMID 5661630 DOI: 10.1016/0003-9861(68)90374-3  0.41
1968 Jerina DM, Daly JW, Witkop B. Additions and Corrections - Deuterium Migration during the Acid-Catalyzed Dehydration of 6-Deutrio-5,6-dihydroxy-3-chloro-1,3-cyclohexadiene, a Nonenzymatic Model for the NIH Shift. Journal of the American Chemical Society. 90: 1094-1094. DOI: 10.1021/Ja01006A609  0.437
1968 Jerina D, Daly J, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. Role of the arene oxide-oxepin system in the metabolism of aromatic substrates Archives of Biochemistry and Biophysics. 128: 176-183. DOI: 10.1016/0003-9861(68)90020-9  0.533
1967 Guroff G, Daly JW, Jerina DM, Renson J, Witkop B, Udenfriend S. Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. Science (New York, N.Y.). 157: 1524-30. PMID 6038165 DOI: 10.1126/Science.157.3796.1524  0.448
1967 Letsinger RL, Caruthers MH, Jerina DM. Reactions of nucleosides on polymer supports. Synthesis of thymidylylthymidylylthymidine. Biochemistry. 6: 1379-88. PMID 6036831 DOI: 10.1021/Bi00857A021  0.641
1967 Jerina DM, Daly JW, Witkop B. Deuterium migration during the acid-catalyzed dehydration of 6-deuterio-5,6-dihydroxy-3-chloro-1,3-cyclohexadi-ene, a nonenzymic model for the NIH shift Journal of the American Chemical Society. 89: 5488-5489. DOI: 10.1021/Ja00997A053  0.436
1967 Jerina DM, Daly JW, Landis WR, Witkop B, Udenfriend S. Intramolecular migration of tritium and deuterium during nonenzymic aromatic hydroxylation Journal of the American Chemical Society. 89: 3347-3349. DOI: 10.1021/Ja00989A044  0.468
1967 Letsinger RL, Jerina DM. Reactivity of ester groups on insoluble polymer supports Journal of Polymer Science Part a-1: Polymer Chemistry. 5: 1977-1986. DOI: 10.1002/pol.1967.150050814  0.435
1964 Letsinger RL, Kornet MJ, Mahadevan V, Jerina DM. Reactions on Polymer Supports Journal of the American Chemical Society. 86: 5163-5165. DOI: 10.1021/ja01077a024  0.429
1964 Letsinger RL, Kornet MJ, Mahadevan V, Jerina DM. Reactions on polymer supports Journal of the American Chemical Society. 86: 5163-5165. DOI: 10.1021/Ja01077A024  0.489
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