Donald M. Jerina - Publications

Affiliations: 
NIH (NIAMDD) 
Website:
https://doi.org/10.1093/carcin/bgr185

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH. Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene. Carcinogenesis. 34: 2184-91. PMID 23671133 DOI: 10.1093/carcin/bgt164  0.96
2012 Tang Y, Liu Z, Ding S, Lin CH, Cai Y, Rodriguez FA, Sayer JM, Jerina DM, Amin S, Broyde S, Geacintov NE. Nuclear magnetic resonance solution structure of an N(2)-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: intercalation from the minor groove with ruptured Watson-Crick base pairing. Biochemistry. 51: 9751-62. PMID 23121427 DOI: 10.1021/bi3013577  0.96
2008 Yagi H, Frank H, Seidel A, Jerina DM. Revised assignment of absolute configuration of the cis- and trans-N6-deoxyadenosine adducts at C14 of (+/-)-11beta,12alpha-dihydroxy-13alpha,14alpha-epoxy-11,12,13,14-tetrahydrodibenzo[a,l]pyrene by stereoselective synthesis. Chemical Research in Toxicology. 21: 2379-92. PMID 19053320 DOI: 10.1021/tx800268f  0.44
2008 Wang Y, Schnetz-Boutaud NC, Kroth H, Yagi H, Sayer JM, Kumar S, Jerina DM, Stone MP. 3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat. Chemical Research in Toxicology. 21: 1348-58. PMID 18549249 DOI: 10.1021/tx7004103  0.72
2007 Yagi H, Jerina DM. Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts. The Journal of Organic Chemistry. 72: 9983-90. PMID 18047370 DOI: 10.1021/jo701705c  0.44
2007 Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H. A structural gap in Dpo4 supports mutagenic bypass of a major benzo [a]pyrene dG adduct in DNA through template misalignment Proceedings of the National Academy of Sciences of the United States of America. 104: 14905-14910. PMID 17848527 DOI: 10.1073/pnas.0700717104  0.96
2007 Yagi H, Jerina DM. Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine. The Journal of Organic Chemistry. 72: 6037-45. PMID 17608435 DOI: 10.1021/jo070303c  0.44
2007 Yagi H, Frank H, Seidel A, Jerina DM. Synthesis and absolute configuration of cis- and trans-opened cyclopenta[cd]pyrene 3,4-oxide N2-deoxyguanosine adducts: conversion to phosphoramidites for oligonucleotide synthesis. Chemical Research in Toxicology. 20: 650-61. PMID 17355153 DOI: 10.1021/tx600286z  0.44
2007 Iyer PC, Yagi H, Sayer JM, Jerina DM. 3'-H-phosphonate synthesis of chiral benzo[a]pyrene diol epoxide adducts at N(2) of deoxyguanosine in oligonucleotides. Chemical Research in Toxicology. 20: 311-5. PMID 17305411 DOI: 10.1021/tx600282y  0.64
2006 Batra VK, Shock DD, Prasad R, Beard WA, Hou EW, Pedersen LC, Sayer JM, Yagi H, Kumar S, Jerina DM, Wilson SH. Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Proceedings of the National Academy of Sciences of the United States of America. 103: 17231-6. PMID 17079493 DOI: 10.1073/pnas.0605069103  0.72
2006 Johnson AA, Sayer JM, Yagi H, Patil SS, Debart F, Maier MA, Corey DR, Vasseur JJ, Burke TR, Marquez VE, Jerina DM, Pommier Y. Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding: role of DNA backbone flexibility and an open catalytic site. The Journal of Biological Chemistry. 281: 32428-38. PMID 16943199 DOI: 10.1074/jbc.M605101200  0.96
2006 Wang B, Sayer JM, Yagi H, Frank H, Seidel A, Jerina DM. Facile interstrand migration of the hydrocarbon moiety of a dibenzo[a,l]pyrene 11,12-diol 13,14-epoxide adduct at N2 of deoxyguanosine in a duplex oligonucleotide. Journal of the American Chemical Society. 128: 10079-84. PMID 16881636 DOI: 10.1021/ja0608038  0.64
2006 Yakovleva L, Handy CJ, Yagi H, Sayer JM, Jerina DM, Shuman S. Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III. Biochemistry. 45: 7644-53. PMID 16768460 DOI: 10.1021/bi060158h  0.96
2006 Choudhary S, Doherty KM, Handy CJ, Sayer JM, Yagi H, Jerina DM, Brosh RM. Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A. The Journal of Biological Chemistry. 281: 6000-9. PMID 16380375 DOI: 10.1074/jbc.M510122200  0.96
2005 Chiapperino D, Cai M, Sayer JM, Yagi H, Kroth H, Masutani C, Hanaoka F, Jerina DM, Cheh AM. Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. The Journal of Biological Chemistry. 280: 39684-92. PMID 16188888 DOI: 10.1074/jbc.M508008200  0.96
2004 Carmella SG, Chen M, Yagi H, Jerina DM, Hecht SS. Analysis of phenanthrols in human urine by gas chromatography-mass spectrometry: potential use in carcinogen metabolite phenotyping. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 2167-74. PMID 15598776  0.44
2004 Doan L, Yagi H, Jerina DM, Whalen DL. Synthesis and hydrolysis of a cis-chlorohydrin derived from a benzo[a]pyrene 7,8-diol 9,10-epoxide. The Journal of Organic Chemistry. 69: 8012-7. PMID 15527284 DOI: 10.1021/jo040234r  0.96
2004 Laco GS, Du W, Kohlhagen G, Sayer JM, Jerina DM, Burke TG, Curran DP, Pommier Y. Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies. Bioorganic & Medicinal Chemistry. 12: 5225-35. PMID 15351405 DOI: 10.1016/j.bmc.2004.06.046  0.96
2004 Tian L, Sayer JM, Jerina DM, Shuman S. Individual nucleotide bases, not base pairs, are critical for triggering site-specific DNA cleavage by vaccinia topoisomerase. The Journal of Biological Chemistry. 279: 39718-26. PMID 15252055 DOI: 10.1074/jbc.M407376200  0.64
2004 Tuske S, Sarafianos SG, Clark AD, Ding J, Naeger LK, White KL, Miller MD, Gibbs CS, Boyer PL, Clark P, Wang G, Gaffney BL, Jones RA, Jerina DM, Hughes SH, et al. Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. Nature Structural & Molecular Biology. 11: 469-74. PMID 15107837 DOI: 10.1038/nsmb760  0.96
2004 Yakovleva L, Handy CJ, Sayer JM, Pirrung M, Jerina DM, Shuman S. Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase. The Journal of Biological Chemistry. 279: 23335-42. PMID 15044474 DOI: 10.1074/jbc.M401203200  0.96
2004 Ling H, Sayer JM, Plosky BS, Yagi H, Boudsocq F, Woodgate R, Jerina DM, Yang W. Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2265-9. PMID 14982998 DOI: 10.1073/pnas.0308332100  0.96
2004 Karle IL, Yagi H, Sayer JM, Jerina DM. Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1433-8. PMID 14757823 DOI: 10.1073/pnas.0307305101  0.96
2004 Graziewicz MA, Sayer JM, Jerina DM, Copeland WC. Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine. Nucleic Acids Research. 32: 397-405. PMID 14729924 DOI: 10.1093/nar/gkh213  0.64
2004 Johnson AA, Sayer JM, Yagi H, Kalena GP, Amin R, Jerina DM, Pommier Y. Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates. The Journal of Biological Chemistry. 279: 7947-55. PMID 14627697 DOI: 10.1074/jbc.M311263200  0.96
2003 Hecht SS, Chen M, Yagi H, Jerina DM, Carmella SG. r-1,t-2,3,c-4-Tetrahydroxy-1,2,3,4-tetrahydrophenanthrene in human urine: a potential biomarker for assessing polycyclic aromatic hydrocarbon metabolic activation. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 12: 1501-8. PMID 14693744  0.44
2003 Khan QA, Kohlhagen G, Marshall R, Austin CA, Kalena GP, Kroth H, Sayer JM, Jerina DM, Pommier Y. Position-specific trapping of topoisomerase II by benzo[a]pyrene diol epoxide adducts: implications for interactions with intercalating anticancer agents. Proceedings of the National Academy of Sciences of the United States of America. 100: 12498-503. PMID 14523238 DOI: 10.1073/pnas.2032456100  0.96
2003 Yakovleva L, Tian L, Sayer JM, Kalena GP, Kroth H, Jerina DM, Shuman S. Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications. The Journal of Biological Chemistry. 278: 42170-7. PMID 12909623 DOI: 10.1074/jbc.M308079200  0.64
2003 Driscoll HC, Matson SW, Sayer JM, Kroth H, Jerina DM, Brosh RM. Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent. The Journal of Biological Chemistry. 278: 41126-35. PMID 12881525 DOI: 10.1074/jbc.M304798200  0.96
2003 Kramata P, Zajc B, Sayer JM, Jerina DM, Wei CS. A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA. The Journal of Biological Chemistry. 278: 14940-8. PMID 12595542 DOI: 10.1074/jbc.M211557200  0.64
2003 Volk DE, Thiviyanathan V, Rice JS, Luxon BA, Shah JH, Yagi H, Sayer JM, Yeh HJC, Jerina DM, Gorenstein DG. Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex Biochemistry. 42: 1410-1420. PMID 12578353 DOI: 10.1021/bi026745u  0.96
2003 Sarafianos SG, Clark AD, Tuske S, Squire CJ, Das K, Sheng D, Ilankumaran P, Ramesha AR, Kroth H, Sayer JM, Jerina DM, Boyer PL, Hughes SH, Arnold E. Trapping HIV-1 reverse transcriptase before and after translocation on DNA. The Journal of Biological Chemistry. 278: 16280-8. PMID 12554739 DOI: 10.1074/jbc.M212911200  0.96
2003 Tian L, Sayer JM, Kroth H, Kalena G, Jerina DM, Shuman S. Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove. The Journal of Biological Chemistry. 278: 9905-11. PMID 12524450 DOI: 10.1074/jbc.M212468200  0.64
2002 Ramos LA, Pontén I, Dipple A, Kumar S, Yagi H, Sayer JM, Kroth H, Kalena G, Jerina DM. Site-specific mutagenesis in Escherichia coli by N2-deoxyguanosine adducts derived from the highly carcinogenic fjord-region benzo[c]phenanthrene 3,4-diol 1,2-epoxides. Chemical Research in Toxicology. 15: 1619-26. PMID 12482245  0.72
2002 Frank EG, Sayer JM, Kroth H, Ohashi E, Ohmori H, Jerina DM, Woodgate R. Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Nucleic Acids Research. 30: 5284-92. PMID 12466554  0.64
2002 Sarafianos SG, Clark AD, Das K, Tuske S, Birktoft JJ, Ilankumaran P, Ramesha AR, Sayer JM, Jerina DM, Boyer PL, Hughes SH, Arnold E. Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. The Embo Journal. 21: 6614-24. PMID 12456667 DOI: 10.1093/emboj/cdf637  0.96
2002 Doan L, Yagi H, Jerina DM, Whalen DL. Chloride ion catalyzed conformational inversion of carbocation intermediates in the hydrolysis of a benzo[a]pyrene 7,8-diol 9,10-epoxide. Journal of the American Chemical Society. 124: 14382-7. PMID 12452712  0.44
2002 Simhadri S, Kramata P, Zajc B, Sayer JM, Jerina DM, Hinkle DC, Wei CS. Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro. Mutation Research. 508: 137-45. PMID 12379469  0.64
2002 Yagi H, Ramesha AR, Kalena G, Sayer JM, Kumar S, Jerina DM. Novel stereoselective control over cis vs trans opening of benzo[c]phenanthrene 3,4-diol 1,2-epoxides by the exocyclic N(2)-amino group of deoxyguanosine in the presence of hexafluoropropan-2-ol. The Journal of Organic Chemistry. 67: 6678-89. PMID 12227797  0.72
2002 Pommier Y, Kohlhagen G, Laco GS, Kroth H, Sayer JM, Jerina DM. Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site. The Journal of Biological Chemistry. 277: 13666-72. PMID 11832494 DOI: 10.1074/jbc.M200209200  0.64
2002 Chiapperino D, Kroth H, Kramarczuk IH, Sayer JM, Masutani C, Hanaoka F, Jerina DM, Cheh AM. Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. The Journal of Biological Chemistry. 277: 11765-71. PMID 11821420 DOI: 10.1074/jbc.M112139200  0.96
2002 Laco GS, Collins JR, Luke BT, Kroth H, Sayer JM, Jerina DM, Pommier Y. Human topoisomerase I inhibition: docking camptothecin and derivatives into a structure-based active site model. Biochemistry. 41: 1428-35. PMID 11814334  0.64
2002 Shen X, Sayer JM, Kroth H, Ponten I, O'Donnell M, Woodgate R, Jerina DM, Goodman MF. Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts. The Journal of Biological Chemistry. 277: 5265-74. PMID 11734560 DOI: 10.1074/jbc.M109575200  0.64
2001 Conney AH, Chang RL, Cui XX, Schiltz M, Yagi H, Jerina DM, Wei SJ. Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons. Advances in Experimental Medicine and Biology. 500: 697-707. PMID 11765016 DOI: 10.1007/978-1-4615-0667-6_102  0.96
2001 Vepachedu S, Ya N, Yagi H, Sayer JM, Jerina DM. Marked Differences in Base Selectivity between DNA and the Free Nucleotides upon Adduct Formation from Bay- and Fjord-Region Diol Epoxides Volume 13, Number 9, September 2000, pp 883-890. Chemical Research in Toxicology. 14: 148. PMID 11749530  0.64
2001 Ilankumaran P, Pannell LK, Gebreselassie P, Pilcher AS, Yagi H, Sayer JM, Jerina DM. Patterns of resistance to exonuclease digestion of oligonucleotides containing polycyclic aromatic hydrocarbon diol epoxide adducts at N6 of deoxyadenosine. Chemical Research in Toxicology. 14: 1330-8. PMID 11559050 DOI: 10.1021/TX010092L  0.64
2001 Peletskaya EN, Boyer PL, Kogon AA, Clark P, Kroth H, Sayer JM, Jerina DM, Hughes SH. Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer. Journal of Virology. 75: 9435-45. PMID 11533206 DOI: 10.1128/JVI.75.19.9435-9445.2001  0.64
2001 Ramos LA, Sayer JM, Yagi H, Shah JH, Dipple A, Jerina DM. Effect of benzo-ring hydroxyl groups on site-specific mutagenesis by tetrahydrobenzo[a]pyrene adducts at N(6) of deoxyadenosine. Chemical Research in Toxicology. 14: 1082-9. PMID 11511182 DOI: 10.1021/TX010076O  0.64
2001 Doan L, Lin B, Yagi H, Jerina DM, Whalen DL. New insights on the mechanisms of the pH-independent reactions of benzo[a]pyrenes 7,8-diol 9,10-epoxides. Journal of the American Chemical Society. 123: 6785-91. PMID 11448182 DOI: 10.1021/ja004359z  0.44
2001 Pontén I, Kroth H, Sayer JM, Dipple A, Jerina DM. Differences between the mutational consequences of replication of cis- and trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-deoxyguanosine adducts in M13mp7L2 constructs. Chemical Research in Toxicology. 14: 720-6. PMID 11409943 DOI: 10.1021/TX0002684  0.64
2001 Kroth H, Yagi H, Sayer JM, Kumar S, Jerina DM. O(6)-allyl protected deoxyguanosine adducts of polycyclic aromatic hydrocarbons as building blocks for the synthesis of oligonucleotides. Chemical Research in Toxicology. 14: 708-19. PMID 11409942 DOI: 10.1021/TX0002637  0.72
2001 Kumar S, Chang RL, Wood AW, Xie JG, Huang MT, Cui XX, Kole PL, Sikka HC, Balani SK, Conney AH, Jerina DM. Tumorigenicity of racemic and optically pure bay region diol epoxides and other derivatives of the nitrogen heterocycle dibenz[a,h]acridine on mouse skin. Carcinogenesis. 22: 951-5. PMID 11375904 DOI: 10.1093/CARCIN/22.6.951  0.96
2001 Pradhan P, Tirumala S, Liu X, Sayer JM, Jerina DM, Yeh HJ. Solution structure of a trans-opened (10S)-dA adduct of (+)-(7S,8R,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a fully complementary DNA duplex: evidence for a major syn conformation. Biochemistry. 40: 5870-81. PMID 11352722 DOI: 10.1021/BI002896Q  0.64
2001 Pontén I, Waters LS, Sayer JM, Pilcher AS, Dipple A, Jerina DM. Influence of adduct position and sequence length on the ligation of oligonucleotides containing benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts into M13mp7L2. Mutagenesis. 16: 65-9. PMID 11139600 DOI: 10.1093/MUTAGE/16.1.65  0.64
2000 Harsch A, Sayer JM, Jerina DM, Vouros P. HPLC-MS/MS identification of positionally isomeric benzo[c]phenanthrene diol epoxide adducts in duplex DNA Chemical Research in Toxicology. 13: 1342-1348. PMID 11123977 DOI: 10.1021/tx000140m  0.96
2000 Volk DE, Rice JS, Luxon BA, Yeh HJC, Liang C, Xie G, Sayer JM, Jerina DM, Gorenstein DG. NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex Biochemistry. 39: 14040-14053. PMID 11087351 DOI: 10.1021/bi001669l  0.96
2000 Chang RL, Wood AW, Kumar S, Lehr RE, Shirai N, Jerina DM, Conney AH. Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice. Carcinogenesis. 21: 1997-2003. PMID 11062160 DOI: 10.1093/CARCIN/21.11.1997  0.96
2000 Pommier Y, Laco GS, Kohlhagen G, Sayer JM, Kroth H, Jerina DM. Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine. Proceedings of the National Academy of Sciences of the United States of America. 97: 10739-44. PMID 10995470 DOI: 10.1073/pnas.190312697  0.64
2000 Vepachedu SR, Ya N, Yagi H, Sayer JM, Jerina DM. Marked differences in base selectivity between DNA and the free nucleotides upon adduct formation from Bay- and Fjord-region diol epoxides. Chemical Research in Toxicology. 13: 883-90. PMID 10995261 DOI: 10.1021/TX000073W  0.64
2000 Kroth H, Yagi H, Seidel A, Jerina DM. New and highly efficient synthesis of cis- and trans-opened Benzo[a]pyrene 7,8-diol 9,10-epoxide adducts at the exocyclic N(2)-amino group of deoxyguanosine. The Journal of Organic Chemistry. 65: 5558-64. PMID 10970294 DOI: 10.1021/JO000522X  0.44
2000 Rao TV, Haber MT, Sayer JM, Jerina DM. Incorporation of 4-thiothymidine into DNA by the Klenow fragment and HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry Letters. 10: 907-10. PMID 10853657 DOI: 10.1016/S0960-894X(00)00123-2  0.64
2000 Pontén I, Sayer JM, Pilcher AS, Yagi H, Kumar S, Jerina DM, Dipple A. Factors determining mutagenic potential for individual cis and trans opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts. Biochemistry. 39: 4136-44. PMID 10747805 DOI: 10.1021/BI991719Q  0.72
2000 Pommier Y, Kohlhagen G, Pourquier P, Sayer JM, Kroth H, Jerina DM. Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages. Proceedings of the National Academy of Sciences of the United States of America. 97: 2040-5. PMID 10688881 DOI: 10.1073/pnas.040397497  0.64
1999 Schiltz M, Cui XX, Lu YP, Yagi H, Jerina DM, Zdzienicka MZ, Chang RL, Conney AH, Wei SJ. Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells. Carcinogenesis. 20: 2279-86. PMID 10590220 DOI: 10.1093/CARCIN/20.12.2279  0.96
1999 Adams JD, Sayer JM, Chadha A, Shirai N, Lehr RE, Kumar S, Jerina DM. The proximate carcinogen trans-3,4-dihydroxy-3,4-dihydro-dibenz[c,h]acridine is oxidized stereoselectively and regioselectively by cytochrome 1A1, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats. Chemico-Biological Interactions. 122: 117-35. PMID 10528997 DOI: 10.1016/S0009-2797(99)00116-7  0.96
1999 Wei SJ, Chang RL, Merkler KA, Gwynne M, Cui XX, Murthy B, Huang MT, Xie JG, Lu YP, Lou YR, Jerina DM, Conney AH. Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene. Carcinogenesis. 20: 1689-96. PMID 10469612 DOI: 10.1093/carcin/20.9.1689  0.96
1999 Page JE, Pilcher AS, Yagi H, Sayer JM, Jerina DM, Dipple A. Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts. Chemical Research in Toxicology. 12: 258-63. PMID 10077488 DOI: 10.1021/tx980244l  0.64
1999 Wei SJ, Chang RL, Wong CQ, Cui XX, Dandamudi N, Lu YP, Merkler KA, Sayer JM, Conney AH, Jerina DM. The ratio of deoxyadenosine to deoxyguanosine adducts formed by (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in purified calf thymus DNA and DNA in V-79 cells is independent of dose. International Journal of Oncology. 14: 509-13. PMID 10024684 DOI: 10.3892/IJO.14.3.509  0.96
1999 Pontén I, Sayer JM, Pilcher AS, Yagi H, Kumar S, Jerina DM, Dipple A. Sequence context effects on mutational properties of cis-opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts in site-specific mutation studies. Biochemistry. 38: 1144-52. PMID 9894012 DOI: 10.1021/bi982436l  0.72
1999 Custer L, Zajc B, Sayer JM, Cullinane C, Phillips DR, Cheh AM, Jerina DM, Bohr VA, Mazur SJ. Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence. Biochemistry. 38: 569-81. PMID 9888796 DOI: 10.1021/bi9813330  0.96
1998 Lipinski LJ, Ross HL, Zajc B, Sayer JM, Jerina DM, Dipple A. Effect of single benzo[a]pyrene diol epoxide-deoxyguanosine adducts on the action of DNA polymerases in vitro. International Journal of Oncology. 13: 269-73. PMID 9664121 DOI: 10.3892/IJO.13.2.269  0.64
1998 Page JE, Zajc B, Oh-hara T, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Sequence context profoundly influences the mutagenic potency of trans- opened benzo[a]pyrene 7,8-diol 9,10-epoxide - Purine nucleoside adducts in site-specific mutation studies Biochemistry. 37: 9127-9137. PMID 9636059 DOI: 10.1021/bi980273v  0.96
1998 Lin B, Doan L, Yagi H, Jerina DM, Whalen DL. Halide effects in the hydrolysis reactions of (+/-)-7beta, 8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo- [a]pyrene. Chemical Research in Toxicology. 11: 630-8. PMID 9625731 DOI: 10.1021/tx9701743  0.44
1998 Dress KR, Gooßen LJ, Liu H, Jerina DM, Sharpless KB. Catalytic aminohydroxylation using adenine-derivatives as the nitrogen source Tetrahedron Letters. 39: 7669-7672. DOI: 10.1016/S0040-4039(98)01716-X  0.96
1997 Schwartz JL, Rice JS, Luxon BA, Sayer JM, Xie G, Yeh HJC, Liu X, Jerina DM, Gorenstein DG. Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: Glycosidic rotation from syn to anti at the modified deoxyadenosine Biochemistry. 36: 11069-11076. PMID 9333324 DOI: 10.1021/bi971306u  0.96
1997 Einolf HJ, Story WT, Marcus CB, Larsen MC, Jefcoate CR, Greenlee WF, Yagi H, Jerina DM, Amin S, Park SS, Gelboin HV, Baird WM. Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis. Chemical Research in Toxicology. 10: 609-17. PMID 9168260 DOI: 10.1021/tx960174n  0.96
1997 Boyd DR, Sharma ND, Agarwal R, Resnick SM, Schocken MJ, Gibson DT, Sayer JM, Yagi H, Jerina DM. Bacterial dioxygenase-catalysed dihydroxylation and chemical resolution routes to enantiopure cis-dihydrodiols of chrysene Journal of the Chemical Society - Perkin Transactions 1. 1715-1723.  0.96
1996 Einolf HJ, Amin S, Yagi H, Jerina DM, Baird WM. Benzo[c]phenanthrene is activated to DNA-binding diol epoxides in the human mammary carcinoma cell line MCF-7 but only limited activation occurs in mouse skin. Carcinogenesis. 17: 2237-44. PMID 8895494 DOI: 10.1093/CARCIN/17.10.2237  0.44
1996 Agarwal R, Yagi H, Jerina DM, Dipple A. Benzo[c]phenanthrene 3,4-dihydrodiol 1,2-epoxide adducts in native and denatured DNA. Carcinogenesis. 17: 1773-6. PMID 8761442 DOI: 10.1093/CARCIN/17.8.1773  0.44
1996 Agarwal R, Canella KA, Yagi H, Jerina DM, Dipple A. Benzo[c]phenanthrene-DNA adducts in mouse epidermis in relation to the tumorigenicities of four configurationally isomeric 3,4-dihydrodiol 1,2-epoxides. Chemical Research in Toxicology. 9: 586-92. PMID 8728502 DOI: 10.1021/tx950148  0.44
1996 Page JE, Christner DF, Lakshman MK, Zajc B, Oh-Hara T, Lipinski LJ, Ross HL, Agarwal R, Szeliga J, Yagi H, Sayer JM, Jerina DM, Dipple A. Effects of polycyclic aromatic hydrocarbon adducts with deoxyguanosine and deoxyadenosine in vivo and in vitro Polycyclic Aromatic Compounds. 10: 171-178.  0.96
1995 Schurter EJ, Yeh HJ, Sayer JM, Lakshman MK, Yagi H, Jerina DM, Gorenstein DG. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Biochemistry. 34: 1364-75. PMID 7827084  0.64
1995 Adams JD, Yagi H, Levin W, Jerina DM. Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats. Chemico-Biological Interactions. 95: 57-77. PMID 7697754 DOI: 10.1016/0009-2797(94)03354-4  0.44
1995 Schurter EJ, Sayer JM, Oh-hara T, Yeh HJ, Yagi H, Luxon BA, Jerina DM, Gorenstein DG. Nuclear magnetic resonance solution structure of an undecanucleotide duplex with a complementary thymidine base opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7R,8S,9R,10S)-7,8-dihydroxy- 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Biochemistry. 34: 9009-20. PMID 7619800  0.96
1995 Lebreton PR, Huang CR, Fernando H, Zajc B, Lakshman MK, Sayer JM, Jerina DM. Multiple fluorescence lifetimes for oligonucleotides containing single, site-specific modifications at guanine and adenine corresponding to trans addition of exocyclic amino groups to (+)-(7R,8S,9S,10R)- and (-)-(7S,8R,9R,10S)-7,8-Dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene Chemical Research in Toxicology. 8: 338-348. PMID 7578919  0.96
1995 Yeh HJ, Sayer JM, Liu X, Altieri AS, Byrd RA, Lakshman MK, Yagi H, Schurter EJ, Gorenstein DG, Jerina DM. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA. Biochemistry. 34: 13570-81. PMID 7577946  0.96
1994 Bigger CA, Cheh A, Latif F, Fishel R, Canella KA, Stafford GA, Yagi H, Jerina DM, Dipple A. DNA strand breaks induced by configurationally isomeric hydrocarbon diol epoxides. Drug Metabolism Reviews. 26: 287-99. PMID 8082571 DOI: 10.3109/03602539409029798  0.96
1994 Conney AH, Chang RL, Jerina DM, Wei SJ. Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite. Drug Metabolism Reviews. 26: 125-63. PMID 8082562 DOI: 10.3109/03602539409029788  0.32
1994 Wei SJ, Chang RL, Hennig E, Cui XX, Merkler KA, Wong CQ, Yagi H, Jerina DM, Conney AH. Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity. Carcinogenesis. 15: 1729-35. PMID 8055656 DOI: 10.1093/CARCIN/15.8.1729  0.44
1994 Christner DF, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene - deoxyadenosine adducts Biochemistry. 33: 14297-14305. PMID 7524675  0.96
1994 Lakshman MK, Xiao W, Sayer JM, Cheh AM, Jerina DM. Synthesis and assignment of absolute configuration to the N6-deoxyadenosine adducts resulting from cis and trans ring-opening of phenanthrene 9,10-oxide Journal of Organic Chemistry. 59: 1755-1760.  0.96
1993 Chang RL, Battista S, Wong CQ, Kumar S, Kole PL, Sikka HC, Balani SK, Jerina DM, Conney AH, Wood AW. Bacterial and mammalian cell mutagenicity of four optically active bay-region 10,11-diol-8,9-epoxides of the nitrogen heterocycle dibenz[a,h]acridine. Carcinogenesis. 14: 2233-7. PMID 8242848 DOI: 10.1093/CARCIN/14.11.2233  0.72
1992 Bigger CA, St John J, Yagi H, Jerina DM, Dipple A. Mutagenic specificities of four stereoisomeric benzo[c]phenanthrene dihydrodiol epoxides. Proceedings of the National Academy of Sciences of the United States of America. 89: 368-72. PMID 1729707 DOI: 10.1073/pnas.89.1.368  0.44
1992 Butch ER, Lau HHS, Shaw KL, Smolarek TA, Schmerold I, Anderson JN, Baird WM, Yagi H, Jerina DM. High selectivity of polyclonal antibodies against dna modified by diastereomeric benzo[a]phenanthrene-3,4-diol-1,2-epoxides Carcinogenesis. 13: 895-899. PMID 1587005 DOI: 10.1093/carcin/13.5.895  0.96
1992 Canella KA, Peltonen K, Yagi H, Jerina DM, Dipple A. Identification of individual benzo[c]phenanthrene dihydrodiol epoxide-DNA adducts by the 32P-postlabeling assay. Chemical Research in Toxicology. 5: 685-90. PMID 1446010 DOI: 10.1021/TX00029A015  0.44
1992 Zajc B, Lakshman MK, Sayer JM, Jerina DM. Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine Tetrahedron Letters. 33: 3409-3412. DOI: 10.1016/S0040-4039(00)92649-2  0.96
1992 Lakshman MK, Yeh HJC, Yagi H, Jerina DM. Synthesis of deoxyadenosine adducts from the highly carcinogenic fjord region diol epoxide of benzo[c]phenanthrene Tetrahedron Letters. 33: 7121-7124. DOI: 10.1016/S0040-4039(00)60852-3  0.96
1992 Lakshman MK, Sayer JM, Jerina DM. Synthesis and site-specific incorporation of a bay-region cis ring-opened tetrahydro epoxide-deoxyadenosine adduct into a DNA oligomer Journal of Organic Chemistry. 57: 3438-3443.  0.96
1992 Lakshman MK, Sayer JM, Yagi H, Jerina DM. Synthesis and duplex-forming properties of a nonanucleotide containing an N6-deoxyadenosine adduct of a bay-region diol epoxide Journal of Organic Chemistry. 57: 4585-4590.  0.96
1991 Jerina DM, Chadha A, Cheh AM, Schurdak ME, Wood AW, Sayer JM. Covalent bonding of bay-region diol epoxides to nucleic acids. Advances in Experimental Medicine and Biology. 283: 533-53. PMID 2069024 DOI: 10.1007/978-1-4684-5877-0_70  0.96
1991 Thakker DR, Boehlert C, Levin W, Ryan DE, Thomas PE, Yagi H, Jerina DM. Novel stereoselectivity of rat liver cytochrome(s) P450 toward enantiomers of the trans-1,2-dihydrodiol of triphenylene. Archives of Biochemistry and Biophysics. 288: 54-63. PMID 1898024 DOI: 10.1016/0003-9861(91)90164-E  0.96
1991 Wei SJ, Chang RL, Wong CQ, Bhachech N, Cui XX, Hennig E, Yagi H, Sayer JM, Jerina DM, Preston BD. Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene. Proceedings of the National Academy of Sciences of the United States of America. 88: 11227-30. PMID 1763036  0.96
1990 Cheh AM, Yagi H, Jerina DM. Stereoselective release of polycyclic aromatic hydrocarbon-deoxyadenosine adducts from DNA by the 32P postlabeling and deoxyribonuclease I/snake venom phosphodiesterase digestion methods. Chemical Research in Toxicology. 3: 545-50. PMID 1966469 DOI: 10.1021/TX00018A009  0.96
1989 Bigger CA, Strandberg J, Yagi H, Jerina DM, Dipple A. Mutagenic specificity of a potent carcinogen, benzo[c]phenanthrene (4R,3S)-dihydrodiol (2S,1R)-epoxide, which reacts with adenine and guanine in DNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 2291-5. PMID 2648399 DOI: 10.1073/PNAS.86.7.2291  0.44
1989 Reardon DB, Bigger CA, Strandberg J, Yagi H, Jerina DM, Dipple A. Sequence selectivity in the reaction of optically active hydrocarbon dihydrodiol epoxides with rat H-ras DNA. Chemical Research in Toxicology. 2: 12-4. PMID 2519225 DOI: 10.1021/TX00007A002  0.44
1987 Ravindranath V, Boyd MR, Jerina DM. Hepatotoxicity of precocene I in rats. Role of metabolic activation in vivo Biochemical Pharmacology. 36: 441-446. PMID 3827936 DOI: 10.1016/0006-2952(87)90348-0  0.96
1987 Chang RL, Wood AW, Conney AH, Yagi H, Sayer JM, Thakker DR, Jerina DM, Levin W. Role of diaxial versus diequatorial hydroxyl groups in the tumorigenic activity of a benzo[a]pyrene bay-region diol epoxide. Proceedings of the National Academy of Sciences of the United States of America. 84: 8633-6. PMID 3479808  0.32
1987 van Bladeren PJ, Balani SK, Sayer JM, Thakker DR, Boyd DR, Ryan DE, Thomas PE, Levin W, Jerina DM. Stereoselective formation of benzo(c)phenanthrene (+)-(3S,4R) and (+)-(5S,6R)-oxides by cytochrome P450c in a highly purified and reconstituted system. Biochemical and Biophysical Research Communications. 145: 160-7. PMID 3109408 DOI: 10.1016/0006-291X(87)91301-5  0.96
1987 Boyd DR, Agarwal SK, Balani SK, Dunlop R, Gadaginamath GS, O'Kane GA, Sharma ND, Jennings WB, Yagi H, Jerina DM. Preparation of oxepines during direct chemical synthesis and facile oxygen walk reactions of arene oxides: Theoretical predictions and experimental evidence Journal of the Chemical Society, Chemical Communications. 1633-1635. DOI: 10.1039/C39870001633  0.96
1987 Yagi H, Sayer JM, Thakker DR, Levin W, Jerina DM. Effects of a 6-fluoro substituent on the solvolytic properties of the diastereomeric 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene Journal of the American Chemical Society. 109: 838-846.  0.96
1986 Smart RC, Huang MT, Chang RL, Sayer JM, Jerina DM, Wood AW, Conney AH. Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice. Carcinogenesis. 7: 1669-75. PMID 3757169 DOI: 10.1093/carcin/7.10.1669  0.64
1986 Jerina DM, Sayer JM, Agarwal SK, Yagi H, Levin W, Wood AW, Conney AH, Pruess-Schwartz D, Baird WM, Pigott MA. Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons. Advances in Experimental Medicine and Biology. 197: 11-30. PMID 3490131 DOI: 10.1007/978-1-4684-5134-4_2  0.64
1986 Smart RC, Huang MT, Chang RL, Sayer JM, Jerina DM, Conney AH. Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3-O-decylellagic acid and 3,3'-di-O-methylellagic acid in mice. Carcinogenesis. 7: 1663-7. PMID 3093111 DOI: 10.1093/carcin/7.10.1663  0.64
1986 Agarwal SK, Boyd DR, Porter HP, Jennings WB, Grossman SJ, Jerina DM. Arene oxides and trans-dihydrodiols of quinoline Tetrahedron Letters. 27: 4253-4256. DOI: 10.1016/S0040-4039(00)94245-X  0.96
1985 Chang RL, Huang MT, Wood AW, Wong CQ, Newmark HL, Yagi H, Sayer JM, Jerina DM, Conney AH. Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. Carcinogenesis. 6: 1127-33. PMID 3926336 DOI: 10.1093/carcin/6.8.1127  0.64
1985 Huang MT, Chang RL, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. Carcinogenesis. 6: 237-42. PMID 3918802 DOI: 10.1093/carcin/6.2.237  0.64
1985 McManus MJ, Berchtold GA, Jerina DM. Nucleophilic addition of azide ion to benzene oxide: A reinvestigation Journal of the American Chemical Society. 107: 2977-2978.  0.96
1984 Jerina DM, Van Bladeren PJ, Yagi H, Gibson DT, Mahadevan V, Neese AS, Koreeda M, Sharma ND, Boyd DR. Synthesis and absolute configuration of the bacterial cis-1,2-, cis-8,9-, and cis-10,11-dihydrodiol metabolites of benz[a]anthracene formed by a strain of Beijerinckia Journal of Organic Chemistry. 49: 3621-3628.  0.96
1983 Ittah Y, Thakker DR, Levin W, Croisy-Delcey M, Ryan DE, Thomas PE, Conney AH, Jerina DM. Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450. Chemico-Biological Interactions. 45: 15-28. PMID 6872097 DOI: 10.1016/0009-2797(83)90039-X  0.96
1983 Levin W, Wood AW, Chang RL, Newman MS, Thakker DR, Conney AH, Jerina DM. The effect of steric strain in the bay-region of polycyclic aromatic hydrocarbons: tumorigenicity of alkyl-substituted benz[a]anthracenes. Cancer Letters. 20: 139-46. PMID 6421476 DOI: 10.1016/0304-3835(83)90042-3  0.96
1983 Huang MT, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Carcinogenesis. 4: 1631-7. PMID 6360409 DOI: 10.1093/carcin/4.12.1631  0.64
1983 Yagi H, Thakker DR, Ittah Y, Croisy-Delcey M, Jerina DM. Synthesis and assignment of absolute configuration to the trans 3,4-dihydrodiols and 3,4-diol-1,2-epoxides of benzo[c]phenanthrene Tetrahedron Letters. 24: 1349-1352. DOI: 10.1016/S0040-4039(00)81653-6  0.96
1983 Lehr RE, Jerina DM. Aza-polycyclic aromatic hydrocarbon carcinogenicity: predictions of reactivity of tetrahydrobenzo ring epoxide derivatives Tetrahedron Letters. 24: 27-30. DOI: 10.1016/S0040-4039(00)81317-9  0.96
1982 Vyas KP, Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Stereoselective metabolism of the optical isomers of trans-1,2-dihydroxy-1,2-dihydrophenanthrene to bay-region diol epoxides by rat liver microsomes. Chemico-Biological Interactions. 38: 203-13. PMID 7055851 DOI: 10.1016/0009-2797(82)90040-0  0.96
1982 Wood AW, Sayer JM, Newmark HL, Yagi H, Michaud DP, Jerina DM, Conney AH. Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 79: 5122-6. PMID 6813854 DOI: 10.1073/pnas.79.17.5122  0.64
1982 van Bladeren PJ, Armstrong RN, Cobb D, Thakker DR, Ryan DE, Thomas PE, Sharma ND, Boyd DR, Levin W, Jerina DM. Stereoselective formation of benz[a]anthracene (+)-(5S,6R)-oxide and (+)-(8R,9S)-oxide by a highly purified and reconstituted system containing cytochrome P-450c. Biochemical and Biophysical Research Communications. 106: 602-9. PMID 6809007 DOI: 10.1016/0006-291X(82)91153-6  0.96
1982 Wood AW, Huang MT, Chang RL, Newmark HL, Lehr RE, Yagi H, Sayer JM, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid. Proceedings of the National Academy of Sciences of the United States of America. 79: 5513-7. PMID 6752950 DOI: 10.1073/pnas.79.18.5513  0.96
1982 Levin W, Wood A, Chang R, Ryan D, Thomas P, Yagi H, Thakker D, Vyas K, Boyd C, Chu SY, Conney A, Jerina D. Oxidative metabolism of polycyclic aromatic hydrocarbons to ultimate carcinogens. Drug Metabolism Reviews. 13: 555-80. PMID 6290166 DOI: 10.3109/03602538209011087  0.96
1982 Sayer JM, Lehr RE, Whalen DL, Yagi H, Jerina DM. Structure-reactivity indices for the hydrolysis of diol epoxides of polycyclic aromatic hydrocarbons Tetrahedron Letters. 23: 4431-4434. DOI: 10.1016/S0040-4039(00)85620-8  0.96
1982 Yagi H, Vyas KP, Tada M, Thakker DR, Jerina DM. Synthesis of the enantiomeric bay-region diol epoxides of benz[a]anthracene and chrysene Journal of Organic Chemistry. 47: 1110-1117.  0.96
1981 Thakker DR, Levin W, Yagi H, Conney AH, Jerina DM. Regio- and stereoselectivity of hepatic cytochrome P-450 toward polycyclic aromatic hydrocarbon substrates. Advances in Experimental Medicine and Biology. 136: 525-39. PMID 7344478  0.96
1981 Jerina DM, Sayer JM, Yagi H, Croisy-Delcey M, Ittah Y, Thakker DR, Wood AW, Chang RL, Levin W, Conney AH. Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene. Advances in Experimental Medicine and Biology. 136: 501-23. PMID 7046379  0.32
1981 Boyd DR, Gadaginamath GS, Sharma ND, Drake AF, Mason SF, Jerina DM. The synthesis of chiral arene oxide metabolites of benz[a]anthracene: Optically active benz[a]anthracene 10,11- and 5,6-oxides Journal of the Chemical Society, Perkin Transactions 1. 2233-2238. DOI: 10.1039/P19810002233  0.96
1981 Kedzierski B, Thakker DR, Armstrong RN, Jerina DM. absolute configuration of the k-region 4,5-dihydrodiols and 4,5-oxide of benzo[a]pyrene Tetrahedron Letters. 22: 405-408. DOI: 10.1016/0040-4039(81)80111-6  0.96
1981 Chao HSI, Berchtold GA, Boyd DR, Dynak JN, Tomaszewski JE, Yagi H, Jerina DM. Migration and retention of deuterium on aromatization of toluene 1,2-oxide and 2,3-oxide to o-cresol Journal of Organic Chemistry. 46: 1948-1950.  0.96
1980 MacLeod MC, Levin W, Conney AH, Lehr RE, Mansfield BK, Jerina DM, Selkirk JK. Metabolism of benzo(e)pyrene by rat liver microsomal enzymes. Carcinogenesis. 1: 165-73. PMID 22282997 DOI: 10.1093/carcin/1.2.165  0.96
1979 Dansette PM, DuBois GC, Jerina DM. Continous fluorometric assay of epoxide hydrase activity. Analytical Biochemistry. 97: 340-5. PMID 525797 DOI: 10.1016/0003-2697(79)90083-6  0.52
1979 Thakker DR, Levin W, Yagi H, Turujman S, Kapadia D, Conney AH, Jerina DM. Absolute stereochemistry of the trans-dihydrodiols formed from benzo[a]anthracene by liver microsomes. Chemico-Biological Interactions. 27: 145-61. PMID 498352 DOI: 10.1016/0009-2797(79)90122-4  0.32
1979 Chang RL, Wood AW, Levin W, Mah HD, Thakker DR, Jerina DM, Conney AH. Differences in mutagenicity and cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-oxide: a synergistic interaction of enantiomers. Proceedings of the National Academy of Sciences of the United States of America. 76: 4280-4. PMID 388437  0.32
1979 Wislocki PG, Buening MK, Levin W, Lehr RE, Thakker DR, Jerina DM, Conney AH. Tumorigenicity of the diastereomeric benz[a]anthracene 3,4-diol-1,2-epoxides and the (+)- and (-)-enantiomers of benz[a]anthracene 3,4-dihydrodiol in newborn mice. Journal of the National Cancer Institute. 63: 201-4. PMID 286829 DOI: 10.1093/jnci/63.1.201  0.32
1979 Lehr RE, Kumar S, Cohenour PT, Jerina DM. Dihydrodiols and diol epoxides of dibenzo[a,i]-and [a,h]pyrene Tetrahedron Letters. 20: 3819-3822. DOI: 10.1016/S0040-4039(01)95533-9  0.96
1979 Whalen DL, Ross AM, Montemarano JA, Thakker DR, Yagi H, Jerina DM. General acid catalysis in the hydrolysis of benzo[a]pyrene 7,8-diol 9,10-epoxides [19] Journal of the American Chemical Society. 101: 5086-5088.  0.96
1979 Yagi H, Thakker DR, Lehr RE, Jerina DM. Benzo-ring diol epoxides of benzo[e]pyrene and triphenylene Journal of Organic Chemistry. 44: 3439-3442.  0.96
1978 Marsh MM, Jerina DM. Calculated properties of arene oxides of biological interest. 1. Molecular orbital examination of simple models. Journal of Medicinal Chemistry. 21: 1298-301. PMID 722737 DOI: 10.1021/jm00210a024  0.96
1978 Thakker DR, Yagi H, Jerina DM. Analysis of polycyclic aromatic hydrocarbons and their metabolites by high-pressure liquid chromatography. Methods in Enzymology. 52: 279-96. PMID 672632 DOI: 10.1016/S0076-6879(78)52030-2  0.96
1978 Dansette PM, Makedonska VB, Jerina DM. Mechanism of catalysis for the hydration of substituted styrene oxides by hepatic epoxide hydrase. Archives of Biochemistry and Biophysics. 187: 290-8. PMID 666312 DOI: 10.1016/0003-9861(78)90037-1  0.52
1978 Regan JD, Francis AA, Dunn WC, Hernandez O, Yagi H, Jerina DM. Repair of DNA damaged by mutagenic metabolites of benzo(a)pyrene in human cells. Chemico-Biological Interactions. 20: 279-87. PMID 657391 DOI: 10.1016/0009-2797(78)90106-0  0.96
1978 Thakker DR, Levin W, Wood AW, Conney AH, Stoming TA, Jerina DM. Metabolic formation of 1,9,10-trihydroxy-9,10-dihydro-3-methylcholanthrene: a potential proximate carcinogen from 3-methylcholanthrene. Journal of the American Chemical Society. 100: 645-7. PMID 624805 DOI: 10.1021/ja00470a057  0.96
1978 Koreeda M, Moore PD, Wislocki PG, Levin W, Yagi H, Jerina DM. Binding of benzo[a]pyrene 7,8-diol-9,10-epoxides to DNA, RNA, and protein of mouse skin occurs with high stereoselectivity. Science (New York, N.Y.). 199: 778-81. PMID 622566  0.96
1978 Buening MK, Wislocki PG, Levin W, Yagi H, Thakker DR, Akagi H, Koreeda M, Jerina DM, Conney AH. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Proceedings of the National Academy of Sciences of the United States of America. 75: 5358-61. PMID 281685  0.32
1978 Jerina DM, Levin W, Thakker DR, Wood AW, Yagi H, Conney AH. Carcinogenicity of benzo[a]pyrene derivatives: The bay region theory Pure and Applied Chemistry. 50: 1033-1044. DOI: 10.1351/pac197850091033  0.96
1978 Whalen DL, Ross AM, Yagi H, Karle JM, Jerina DM. Stereoelectronic factors in the solvolysis of bay region diol epoxides of polycyclic aromatic hydrocarbons [8] Journal of the American Chemical Society. 100: 5218-5221. DOI: 10.1021/ja00484a058  0.96
1978 KARLE JM, MAH HD, JERINA DM, YAGI H. ChemInform Abstract: SYNTHESIS OF DIHYDRODIOLS FROM CHRYSENE AND DIBENZO(A,H)ANTHRACENE Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197805212  0.44
1978 Koreeda M, Akhtar MN, Boyd DR, Neill JD, Gibson DT, Jerina DM. Absolute stereochemistry of cis-1,2-, trans-1,2-, and cis-3,4-dihydrodiol metabolites of phenanthrene Journal of Organic Chemistry. 43: 1023-1027.  0.96
1977 Bresnick E, Stoming TA, Vaught JB, Thakker DR, Jerina DM. Nuclear metabolism of benzo(a)pyrene and of (+/-)-trans-7-8-dihydroxy-7-8,-dihydrobenzo(a)pyrene. Comparative chromatographic analysis of alkylated DNA. Archives of Biochemistry and Biophysics. 183: 31-7. PMID 907356 DOI: 10.1016/0003-9861(77)90415-5  0.96
1977 Yagi H, Akagi H, Thakker DR, Mah HD, Koreeda M, Jerina DM. Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene. Journal of the American Chemical Society. 99: 2358-9. PMID 864141  0.96
1977 Thakker DR, Yagi H, Akagi H, Koreeda M, Lu AH, Levin W, Wood AW, Conney AH, Jerina DM. Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides. Chemico-Biological Interactions. 16: 281-300. PMID 862130 DOI: 10.1016/0009-2797(77)90108-9  0.96
1977 Bresnick E, Mukhtar H, Stoming TA, Dansette PM, Jerina DM. Effect of phenobarbital and 3-methylcholanthrene administration on epoxide hydrase levels in liver microsomes. Biochemical Pharmacology. 26: 891-2. PMID 861055 DOI: 10.1016/0006-2952(77)90406-3  0.52
1977 Yagi H, Thakker DR, Hernandez O, Koreeda M, Jerina DM. Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene. Journal of the American Chemical Society. 99: 1604-11. PMID 839009  0.96
1977 Lehr RE, Jerina DM. Metabolic activations of polycyclic hydrocarbons - Structure-activity relationships Archives of Toxicology. 39: 1-6. PMID 579975 DOI: 10.1007/BF00343269  0.96
1977 Wood AW, Levin W, Ryan D, Thomas PE, Yagi H, Mah HD, Thakker DR, Jerina DM, Conney AH. High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene. Biochemical and Biophysical Research Communications. 78: 847-54. PMID 334179 DOI: 10.1016/0006-291X(77)90500-9  0.96
1977 Wood AW, Chang RL, Levin W, Yagi H, Thakker DR, Jerina DM, Conney AH. Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides. Biochemical and Biophysical Research Communications. 77: 1389-96. PMID 332178 DOI: 10.1016/S0006-291X(77)80133-2  0.32
1977 Wood AW, Chang RL, Levin W, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Mutagenicity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides Proceedings of the National Academy of Sciences of the United States of America. 74: 2746-2750. PMID 331315 DOI: 10.1073/pnas.74.7.2746  0.32
1977 Lehr RE, Jerina DM. Relationships of quantum mechanical calculations, relative mutagenicity of benzom anthracene diol epoxides, and “Bay region” concept of aromatic hydrocarbon carcinogenicity Journal of Toxicology and Environmental Health. 2: 1259-1265. PMID 328916 DOI: 10.1080/15287397709529528  0.96
1977 Remsen J, Jerina D, Yagi H, Cerutti P. In vitro reaction of radioactive 7β,8α,-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene and 7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene with DNA Biochemical and Biophysical Research Communications. 74: 934-940. PMID 320977 DOI: 10.1016/0006-291X(77)91608-4  0.44
1977 Wood AW, Levin W, Chang RL, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. Proceedings of the National Academy of Sciences of the United States of America. 74: 3176-9. PMID 269381 DOI: 10.1073/pnas.74.8.3176  0.32
1977 Whalen DL, Montemarano JA, Thakker DR, Yagi H, Jerina DM. Changes of mechanisms and product distributions in the hydrolysis of benzo[a]pyrene-7,8-diol 9,10-epoxide metabolites induced by changes in pH. Journal of the American Chemical Society. 99: 5522-4. PMID 18500  0.96
1977 Lindsay Smith JR, Shaw BAJ, Foulkes DM, Jeffrey AM, Jerina DM. Aromatic hydroxylation. Part 6. Oxidation of naphthalene by di-oxygen in the presence of iron(II) salts Journal of the Chemical Society, Perkin Transactions 2. 1583-1589. DOI: 10.1039/P29770001583  0.96
1977 Lehr RE, Schaefer-Ridder M, Jerina DM. Synthesis and reactivity of diol epoxides derived from non-K-region trans-dihydrodiols of benzo[a]anthracene Tetrahedron Letters. 18: 539-542. DOI: 10.1016/S0040-4039(01)92688-7  0.96
1977 Karle JM, Mah HD, Jerina DM, Yagi H. Synthesis of dihydrodiols from chrysene and dibenzo[a,h]anthracene Tetrahedron Letters. 18: 4021-4024. DOI: 10.1016/S0040-4039(01)83415-8  0.96
1977 Ziffer H, Kabuto K, Gibson DT, Kobal VM, Jerina DM. The absolute stereochemistry of several cis-dihydrodiols microbially produced from substituted benzenes Tetrahedron. 33: 2491-2496. DOI: 10.1016/0040-4020(77)80070-7  0.96
1976 Levin W, Wood AW, Yagi H, Dansette PM, Jerina DM, Conney AH. Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin. Proceedings of the National Academy of Sciences of the United States of America. 73: 243-7. PMID 1061121 DOI: 10.1073/pnas.73.1.243  0.52
1976 Boyd DR, Campbell RM, Craig HC, Watson CG, Daly JW, Jerina DM. Mechanism of aromatic hydroxylation in fungi. Evidence for the formation of arene oxides. Journal of the Chemical Society. Perkin Transactions 1. 2438-43. PMID 1033945 DOI: 10.1039/P19760002438  0.8
1976 Koreeda M, Moore PD, Yagi H, Yeh HJ, Jerina DM. Alkylation of polyguanylic acid at the 2-amino group and phosphate by the potent mutagen (+/-)-7beta,8alpha-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Journal of the American Chemical Society. 98: 6720-2. PMID 972227  0.96
1976 Jerina DM, Selander H, Yagi H, Wells MC, Davey JF, Mahadevan V, Gibson DT. Dihydrodiols from anthracene and phenanthrene Journal of the American Chemical Society. 98: 5988-5996. PMID 965633 DOI: 10.1021/ja00435a035  0.96
1976 Wood AW, Levin W, Lu AYH, Ryan D, West SB, Lehr RE, Schaefer-Ridder M, Jerina DM, Conney AH. Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: Evidence for bay region activation of carcinogenic polycyclic hydrocarbons Biochemical and Biophysical Research Communications. 72: 680-686. PMID 791280 DOI: 10.1016/S0006-291X(76)80093-9  0.32
1975 Selander HG, Jerina DM, Daly JW. Metabolism of acetanilide with hepatic microsomes and reconstituted cytochrome monoxygenase systems. Archives of Biochemistry and Biophysics. 164: 241-6. PMID 4429351 DOI: 10.1016/0003-9861(74)90028-9  0.44
1975 Akhtar MN, Boyd DR, Thompson NJ, Koreeda M, Gibson DT, Mahadevan V, Jerina DM. Absolute sterochemistry of the dihydroanthracene-cis- and -trans-1,2-diols produced from anthracene by mammals and bacteria. Journal of the Chemical Society. Perkin Transactions 1. 2506-11. PMID 1239455  0.96
1975 Hayakawa T, Udenfriend S, Yagi H, Jerina DM. Substrates and inhibitors of hepatic glutathione-S-epoxide transferase. Archives of Biochemistry and Biophysics. 170: 438-51. PMID 1190775 DOI: 10.1016/0003-9861(75)90139-3  0.96
1975 Selander HG, Jerina DM, Piccolo DE, Berchtold GA. Letter: SyntheSis of 3- and 4-chlorobenzene oxides. Unexpected trapping results during metabolism of ]14-c[chlorobenzene by hepatic microsomes. Journal of the American Chemical Society. 97: 4428-30. PMID 1141606  0.96
1975 Wood AW, Goode RL, Chang RL, Levin W, Conney AH, Yagi H, Dansette PM, Jerina DM. Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols. Proceedings of the National Academy of Sciences of the United States of America. 72: 3176-80. PMID 1103140 DOI: 10.1073/pnas.72.8.3176  0.52
1975 Selander HG, Jerina DM, Daly JW. Metobolism of chlorobenzene with hepatic microsomes and solubilized cytochrome P-450 systems. Archives of Biochemistry and Biophysics. 168: 309-21. PMID 806264 DOI: 10.1016/0003-9861(75)90255-6  0.44
1975 Jeffrey AM, Yeh HJ, Jerina DM, Patel TR, Davey JF, Gibson DT. Initial reactions in the oxidation of naphthalene by Pseudomonas putida. Biochemistry. 14: 575-84. PMID 234247  0.96
1975 Akhtar MN, Boyd DR, Thompson NJ, Koreeda M, Gibson DT, Mahadevan V, Jerina DM. Absolute stereochemistry of the dihydroanthracene-cis- and -trans-1,2-diols produced from anthracene by mammals and bacteria Journal of the Chemical Society, Perkin Transactions 1. 2506-2511.  0.32
1974 Jerina DM, Daly JW. Arene oxides: a new aspect of drug metabolism. Science (New York, N.Y.). 185: 573-82. PMID 4841570 DOI: 10.1126/science.185.4151.573  0.52
1974 Holder G, Yagi H, Dansette P, Jerina DM, Levin W, Lu AY, Conney AH. Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proceedings of the National Academy of Sciences of the United States of America. 71: 4356-4360. PMID 4530987 DOI: 10.1073/pnas.71.11.4356  0.96
1974 Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7  0.8
1974 Bjørgo J, Boyd DR, Watson CG, Jennings WB, Jerina DM. E–Z-isomerism in aldimines Journal of the Chemical Society, Perkin Transactions 2. 1081-1084. DOI: 10.1039/P29740001081  0.96
1974 Jerina DM, Witkop B, McIntosh CL, Chapman OL. Photolysis of arene oxides at low temperatures. Oxygen walks and keto tautomers of phenols [14] Journal of the American Chemical Society. 96: 5578-5580. DOI: 10.1021/ja00824a050  0.96
1974 Jeffrey AM, Yeh HJC, Jerina DM. Synthesis of cis-1,2-dihydroxy-1,2-dihydronaphthalene and cis-1,4-dihydroxy-1,4-dihydronaphthalene Journal of Organic Chemistry. 39: 1405-1407.  0.96
1973 Ferris JP, Fasco MJ, Stylianopoulou FL, Jerina DM, Daly JW, Jeffrey AM. Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes. Archives of Biochemistry and Biophysics. 156: 97-103. PMID 4730481 DOI: 10.1016/0003-9861(73)90345-7  0.96
1973 Reed DJ, Vimmerstedt J, Jerina DM, Daly JW. Formation of phenols from aromatic subtrates by plant and animal mono-oxygenases: The effect of adjacent deuteriums on the magnitude of the NIH shift of tritium Archives of Biochemistry and Biophysics. 154: 642-647. PMID 4691507 DOI: 10.1016/0003-9861(73)90019-2  0.96
1973 Oesch F, Jerina DM, Daly JW, Rice JM. Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase Chemico-Biological Interactions. 6: 189-202. PMID 4632460 DOI: 10.1016/0009-2797(73)90071-9  0.96
1973 KASPEREK GJ, BRUICE TC, YAGI H, KAUBISCH N, JERINA DM. ChemInform Abstract: SOLVOLYSE-CHEMIE VON 1,4-DIMETHYL-BENZOLOXID, NEUER MECHANISMUS DER NIH-VERSCHIEBUNG Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197302124  0.4
1972 Jerina DM, Kaubisch N, Daly JW. Arene oxides as intermediates in the metabolism of aromatic substrates: alkyl and oxygen migrations during isomerization of alkylated arene oxides. Proceedings of the National Academy of Sciences of the United States of America. 68: 2545-8. PMID 5289888 DOI: 10.1073/pnas.68.10.2545  0.4
1972 Oesch F, Kaubisch N, Jerina DM, Daly JW. Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors. Biochemistry. 10: 4858-66. PMID 5134533 DOI: 10.1021/bi00802a005  0.44
1972 Oesch F, Jerina DM, Daly JW. Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes. Archives of Biochemistry and Biophysics. 144: 253-61. PMID 5117530 DOI: 10.1016/0003-9861(71)90476-0  0.36
1972 Kaubisch N, Daly JW, Jerina DM. Arene oxides as intermediates in the oxidative metabolism of aromatic compounds. Isomerization of methyl-substituted arene oxides. Biochemistry. 11: 3080-8. PMID 5041913 DOI: 10.1021/bi00766a022  0.4
1972 Jeffrey AM, Jerina DM, Self R, Evans WC. The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp. The Biochemical Journal. 130: 383-90. PMID 4198081  0.96
1972 Daly JW, Jerina DM, Witkop B. Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds. Experientia. 28: 1129-49. PMID 4117670 DOI: 10.1007/BF01946135  0.96
1972 Boyd DR, Watson CG, Jennings WB, Jerina DM. E- and Z-aldimines Journal of the Chemical Society, Chemical Communications. 183. DOI: 10.1039/C39720000183  0.96
1971 Jerina DM, Daly JW, Jeffrey AM, Gibson DT. Cis-1,2-dihydroxy-1,2-dihydronaphthalene: a bacterial metabolite from naphthalene. Archives of Biochemistry and Biophysics. 142: 394-6. PMID 5545490 DOI: 10.1016/0003-9861(71)90298-0  0.96
1971 Jerina DM, Daly JW, Witkop B. Migration of substituents during Hydroxylation of aromatic substrates (NIH shift). Oxidations with peroxytrifluoroacetic acid. Biochemistry. 10: 366-72. PMID 5543961 DOI: 10.1021/bi00779a002  0.96
1970 Daly JW, Jerina DM. Aerobic aromatic hydroxylation catalyzed by horseradish peroxidase: absense of NIH shift. Biochimica Et Biophysica Acta. 208: 340-2. PMID 5420986 DOI: 10.1016/0304-4165(70)90256-4  0.48
1970 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. 1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. Biochemistry. 9: 147-56. PMID 5411205 DOI: 10.1021/bi00803a019  0.96
1970 Daly JW, Jerina DM, Ziffer H, Witkop B, Klärner FG, Vogel E. Enzymatic hydration of 8,9-indan oxide, Homoallylic addition of water. Journal of the American Chemical Society. 92: 702-3. PMID 5411062 DOI: 10.1021/ja00706a048  0.96
1970 Boyd DR, Jennings WB, Spratt R, Jerina DM. Stereochemical control in oxaziridine synthesis from nitrones and imines Journal of the Chemical Society D: Chemical Communications. 745-746. DOI: 10.1039/C29700000745  0.96
1970 Jerina DM, Boyd DR, Paolillo L, Becker ED. Stereospecific chemical shifts and coupling constants in 15N-oxaziridines Tetrahedron Letters. 11: 1483-1484. DOI: 10.1016/S0040-4039(01)98001-3  0.96
1970 BOYD DR, JERINA DM, DALY JW. ChemInform Abstract: OPTISCH AKTIVES 1,2-NAPHTHALIN-OXID Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/chin.197049305  0.32
1968 Daly J, Jerina D, Witkop B. Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes. I. Influence of ring substitutents. Archives of Biochemistry and Biophysics. 128: 517-27. PMID 5698035 DOI: 10.1016/0003-9861(68)90059-3  0.96
1968 Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. Journal of the American Chemical Society. 90: 6525-7. PMID 5682453 DOI: 10.1021/ja01025a058  0.96
1968 Jerina DM, Daly JW, Witkop B. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. II. Synthesis of 3,4-toluene-4-2H oxide and subsequent "NIH shift" to 4-hydroxytoluene-3-2H. Journal of the American Chemical Society. 90: 6523-5. PMID 5682452 DOI: 10.1021/ja01025a057  0.96
1967 Guroff G, Daly JW, Jerina DM, Renson J, Witkop B, Udenfriend S. Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. Science (New York, N.Y.). 157: 1524-30. PMID 6038165 DOI: 10.1126/science.157.3796.1524  0.96
1967 Letsinger RL, Caruthers MH, Jerina DM. Reactions of nucleosides on polymer supports. Synthesis of thymidylylthymidylylthymidine. Biochemistry. 6: 1379-88. PMID 6036831 DOI: 10.1021/bi00857a021  0.96
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