| Year |
Citation |
Score |
| 2020 |
Ghosh S, Goldgur Y, Shuman S. Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Research. PMID 32034423 DOI: 10.1093/Nar/Gkaa075 |
0.587 |
|
| 2019 |
Jia N, Unciuleac MC, Xue C, Greene EC, Patel DJ, Shuman S. Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31740608 DOI: 10.1073/pnas.1913546116 |
0.58 |
|
| 2019 |
Munir A, Shuman S. Structure-function analysis of the phosphoesterase component of the nucleic acid end-healing enzyme HD-Pnk. Journal of Bacteriology. PMID 31160396 DOI: 10.1128/Jb.00292-19 |
0.388 |
|
| 2019 |
Garg A, Goldgur Y, Sanchez AM, Schwer B, Shuman S. Structure of fission yeast transcription factor Pho7 bound to promoter DNA and effect of Pho7 mutations on DNA binding and phosphate homeostasis. Molecular and Cellular Biology. PMID 31010807 DOI: 10.1128/Mcb.00132-19 |
0.52 |
|
| 2019 |
Ejaz A, Goldgur Y, Shuman S. Activity and structure of MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster. The Journal of Biological Chemistry. PMID 30894417 DOI: 10.1074/Jbc.Ra119.008049 |
0.634 |
|
| 2019 |
Unciuleac MC, Goldgur Y, Shuman S. Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates. The Journal of Biological Chemistry. PMID 30718283 DOI: 10.1074/Jbc.Ra119.007445 |
0.559 |
|
| 2018 |
Ejaz A, Shuman S. Characterization of Lhr-Core DNA helicase and Mn-dependent DNA nuclease components of a bacterial gene cluster encoding nucleic acid repair enzymes. The Journal of Biological Chemistry. PMID 30224353 DOI: 10.1074/Jbc.Ra118.005296 |
0.611 |
|
| 2018 |
Garg A, Goldgur Y, Schwer B, Shuman S. Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis. Nucleic Acids Research. PMID 30212894 DOI: 10.1093/nar/gky827 |
0.393 |
|
| 2018 |
Munir A, Banerjee A, Shuman S. NAD+-dependent synthesis of a 5'-phospho-ADP-ribosylated RNA/DNA cap by RNA 2'-phosphotransferase Tpt1. Nucleic Acids Research. PMID 30202863 DOI: 10.1093/Nar/Gky792 |
0.317 |
|
| 2018 |
Schmier BJ, Shuman S. HD-Pnk, a nucleic acid end-healing enzyme, abets resistance to killing by ionizing radiation and mitomycin C. Journal of Bacteriology. PMID 29891641 DOI: 10.1128/Jb.00151-18 |
0.4 |
|
| 2017 |
Ejaz A, Ordonez H, Jacewicz A, Ferrao R, Shuman S. Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases. Nucleic Acids Research. PMID 29165676 DOI: 10.1093/Nar/Gkx1163 |
0.513 |
|
| 2017 |
Schwer B, Sanchez AM, Garg A, Chatterjee D, Shuman S. Defining the DNA Binding Site Recognized by the Fission Yeast Zn2Cys6 Transcription Factor Pho7 and Its Role in Phosphate Homeostasis. Mbio. 8. PMID 28811350 DOI: 10.1128/Mbio.01218-17 |
0.392 |
|
| 2017 |
Uson ML, Ghosh S, Shuman S. The DNA repair repertoire of Mycobacterium smegmatis FenA includes the incision of DNA 5' flaps and the removal of 5' adenylylated products of aborted nick ligation. Journal of Bacteriology. PMID 28630124 DOI: 10.1128/Jb.00304-17 |
0.613 |
|
| 2017 |
Reed BR, Yakovleva L, Shuman S, Ghose R. Characterization of DNA binding by the isolated N-terminal domain of vaccinia virus DNA topoisomerase IB. Biochemistry. PMID 28570045 DOI: 10.1021/Acs.Biochem.7B00042 |
0.607 |
|
| 2017 |
Unciuleac MC, Goldgur Y, Shuman S. Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223499 DOI: 10.1073/Pnas.1619220114 |
0.306 |
|
| 2016 |
Gupta R, Unciuleac MC, Shuman S, Glickman MS. Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases. Nucleic Acids Research. PMID 27899634 DOI: 10.1093/Nar/Gkw1130 |
0.549 |
|
| 2016 |
Gupta R, Chatterjee D, Glickman MS, Shuman S. Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase. Nucleic Acids Research. PMID 27899559 DOI: 10.1093/Nar/Gkw1046 |
0.353 |
|
| 2016 |
Munir A, Shuman S. Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2',3' -phosphoesterase HD domain and a C-terminal 5' -OH polynucleotide kinase domain. Journal of Bacteriology. PMID 27895092 DOI: 10.1128/Jb.00739-16 |
0.401 |
|
| 2016 |
Remus BS, Schwer B, Shuman S. Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis. Rna (New York, N.Y.). PMID 27492257 DOI: 10.1261/Rna.057455.116 |
0.31 |
|
| 2016 |
Cho JE, Huang SN, Burgers PM, Shuman S, Pommier Y, Jinks-Robertson S. Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo. Nucleic Acids Research. PMID 27257064 DOI: 10.1093/Nar/Gkw495 |
0.422 |
|
| 2016 |
Chauleau M, Shuman S. Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD+-dependent DNA ligase (LigA). Nucleic Acids Research. PMID 26857547 DOI: 10.1093/Nar/Gkw049 |
0.51 |
|
| 2016 |
Dai P, Wang W, Li T, Serna-Tamayo C, Shuman S, Chen Z, Deng L. 455 Inhibition of the cytosolic DNA sensor cyclic GMP-AMP synthase by poxviral virulence factor E3 Journal of Investigative Dermatology. 136: S81. DOI: 10.1016/j.jid.2016.02.491 |
0.326 |
|
| 2015 |
Maughan WP, Shuman S. Characterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3. Journal of Bacteriology. 197: 3616-24. PMID 26350128 DOI: 10.1128/Jb.00631-15 |
0.491 |
|
| 2015 |
Gupta R, Shuman S, Glickman MS. RecF and RecR Play Critical Roles in the Homologous Recombination and Single-Strand Annealing Pathways of Mycobacteria. Journal of Bacteriology. 197: 3121-32. PMID 26195593 DOI: 10.1128/Jb.00290-15 |
0.495 |
|
| 2015 |
Uson ML, Ordonez H, Shuman S. Mycobacterium smegmatis HelY Is an RNA-Activated ATPase/dATPase and 3'-to-5' Helicase That Unwinds 3'-Tailed RNA Duplexes and RNA:DNA Hybrids. Journal of Bacteriology. 197: 3057-65. PMID 26170411 DOI: 10.1128/Jb.00418-15 |
0.385 |
|
| 2015 |
Chauleau M, Jacewicz A, Shuman S. DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition. Nucleic Acids Research. PMID 26007660 DOI: 10.1093/Nar/Gkv501 |
0.572 |
|
| 2015 |
Jacewicz A, Shuman S. Biochemical characterization of Mycobacterium smegmatis RnhC (MSMEG_4305), a bifunctional enzyme composed of autonomous N-terminal type I ribonuclease H and C-terminal acid phosphatase domains. Journal of Bacteriology. PMID 25986906 DOI: 10.1128/Jb.00268-15 |
0.553 |
|
| 2015 |
Chauleau M, Das U, Shuman S. Effects of DNA3'pp5'G capping on 3' end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance. Nucleic Acids Research. 43: 3197-207. PMID 25753667 DOI: 10.1093/Nar/Gkv179 |
0.604 |
|
| 2014 |
Ordonez H, Shuman S. Mycobacterium smegmatis DinB2 misincorporates deoxyribonucleotides and ribonucleotides during templated synthesis and lesion bypass. Nucleic Acids Research. 42: 12722-34. PMID 25352547 DOI: 10.1093/Nar/Gku1027 |
0.479 |
|
| 2014 |
Das U, Wang LK, Smith P, Munir A, Shuman S. Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide. Journal of Bacteriology. 196: 4285-92. PMID 25266383 DOI: 10.1128/Jb.02197-14 |
0.368 |
|
| 2014 |
Remus BS, Jacewicz A, Shuman S. Structure and mechanism of E. coli RNA 2',3'-cyclic phosphodiesterase. Rna (New York, N.Y.). 20: 1697-705. PMID 25239919 DOI: 10.1261/Rna.046797.114 |
0.303 |
|
| 2014 |
Ordonez H, Uson ML, Shuman S. Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation. Nucleic Acids Research. 42: 11056-70. PMID 25200080 DOI: 10.1093/Nar/Gku752 |
0.586 |
|
| 2014 |
Das U, Chauleau M, Ordonez H, Shuman S. Impact of DNA3'pp5'G capping on repair reactions at DNA 3' ends. Proceedings of the National Academy of Sciences of the United States of America. 111: 11317-22. PMID 25049385 DOI: 10.1073/Pnas.1409203111 |
0.627 |
|
| 2014 |
Doamekpor SK, Sanchez AM, Schwer B, Shuman S, Lima CD. How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes & Development. 28: 1323-36. PMID 24939935 DOI: 10.1101/Gad.242768.114 |
0.308 |
|
| 2014 |
Kyrieleis OJ, Chang J, de la Peña M, Shuman S, Cusack S. Crystal structure of vaccinia virus mRNA capping enzyme provides insights into the mechanism and evolution of the capping apparatus. Structure (London, England : 1993). 22: 452-65. PMID 24607143 DOI: 10.1016/J.Str.2013.12.014 |
0.332 |
|
| 2014 |
Remus BS, Shuman S. Distinctive kinetics and substrate specificities of plant and fungal tRNA ligases. Rna (New York, N.Y.). 20: 462-73. PMID 24554441 DOI: 10.1261/Rna.043752.113 |
0.351 |
|
| 2014 |
Schmier BJ, Shuman S. Effects of 3'-OH and 5'-PO4 base mispairs and damaged base lesions on the fidelity of nick sealing by Deinococcus radiodurans RNA ligase. Journal of Bacteriology. 196: 1704-12. PMID 24532777 DOI: 10.1128/Jb.00020-14 |
0.311 |
|
| 2013 |
Das U, Chakravarty AK, Remus BS, Shuman S. Rewriting the rules for end joining via enzymatic splicing of DNA 3'-PO4 and 5'-OH ends. Proceedings of the National Academy of Sciences of the United States of America. 110: 20437-42. PMID 24218597 DOI: 10.1073/Pnas.1314289110 |
0.615 |
|
| 2013 |
Chauleau M, Shuman S. Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3'-OH base mispairs and damaged base lesions. Rna (New York, N.Y.). 19: 1840-7. PMID 24158792 DOI: 10.1261/Rna.041731.113 |
0.374 |
|
| 2013 |
Unciuleac MC, Shuman S. Discrimination of RNA from DNA by polynucleotide phosphorylase. Biochemistry. 52: 6702-11. PMID 23980617 DOI: 10.1021/Bi401041V |
0.526 |
|
| 2013 |
Das U, Wang LK, Smith P, Shuman S. Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkp•hen1 RNA repair system. Biochemistry. 52: 4734-43. PMID 23721485 DOI: 10.1021/Bi400412X |
0.322 |
|
| 2013 |
Wang LK, Smith P, Shuman S. Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system. Nucleic Acids Research. 41: 5864-73. PMID 23595150 DOI: 10.1093/Nar/Gkt221 |
0.306 |
|
| 2013 |
Unciuleac MC, Shuman S. Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase. Biochemistry. 52: 2967-81. PMID 23560592 DOI: 10.1021/Bi400281W |
0.515 |
|
| 2013 |
Ordonez H, Shuman S. Mycobacterium smegmatis Lhr Is a DNA-dependent ATPase and a 3'-to-5' DNA translocase and helicase that prefers to unwind 3'-tailed RNA:DNA hybrids. The Journal of Biological Chemistry. 288: 14125-34. PMID 23549043 DOI: 10.1074/Jbc.M113.466854 |
0.606 |
|
| 2013 |
Yakovleva L, Shuman S. Chemical mutagenesis of vaccinia DNA topoisomerase lysine 167 provides insights to the catalysis of DNA transesterification. Biochemistry. 52: 984-91. PMID 23317114 DOI: 10.1021/Bi301643H |
0.455 |
|
| 2013 |
Gupta R, Ryzhikov M, Koroleva O, Unciuleac M, Shuman S, Korolev S, Glickman MS. A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing. Nucleic Acids Research. 41: 2284-95. PMID 23295671 DOI: 10.1093/Nar/Gks1298 |
0.583 |
|
| 2012 |
Zhu H, Bhattarai H, Yan HG, Shuman S, Glickman MS. Characterization of Mycobacterium smegmatis PolD2 and PolD1 as RNA/DNA polymerases homologous to the POL domain of bacterial DNA ligase D. Biochemistry. 51: 10147-58. PMID 23198659 DOI: 10.1021/Bi301202E |
0.596 |
|
| 2012 |
Meineke B, Kast A, Schwer B, Meinhardt F, Shuman S, Klassen R. A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair. Rna (New York, N.Y.). 18: 1716-24. PMID 22836353 DOI: 10.1261/Rna.034132.112 |
0.318 |
|
| 2012 |
Samai P, Shuman S. Kinetic analysis of DNA strand joining by Chlorella virus DNA ligase and the role of nucleotidyltransferase motif VI in ligase adenylylation. The Journal of Biological Chemistry. 287: 28609-18. PMID 22745124 DOI: 10.1074/Jbc.M112.380428 |
0.568 |
|
| 2012 |
Yakovleva L, Shuman S. Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3' to 5' translocase and helicase activities. Nucleic Acids Research. 40: 7465-75. PMID 22641846 DOI: 10.1093/Nar/Gks417 |
0.559 |
|
| 2012 |
Chakravarty AK, Subbotin R, Chait BT, Shuman S. RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates. Proceedings of the National Academy of Sciences of the United States of America. 109: 6072-7. PMID 22474365 DOI: 10.1073/Pnas.1201207109 |
0.35 |
|
| 2012 |
Ordonez H, Unciuleac M, Shuman S. Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3'-5' translocase and duplex unwinding activities. Nucleic Acids Research. 40: 4604-14. PMID 22287622 DOI: 10.1093/Nar/Gks046 |
0.473 |
|
| 2012 |
Natarajan A, Dutta K, Temel DB, Nair PA, Shuman S, Ghose R. Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D. Nucleic Acids Research. 40: 2076-88. PMID 22084199 DOI: 10.1093/Nar/Gkr950 |
0.544 |
|
| 2012 |
Das U, Smith P, Shuman S. Structural insights to the metal specificity of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme family. Nucleic Acids Research. 40: 828-36. PMID 21965539 DOI: 10.1093/Nar/Gkr767 |
0.329 |
|
| 2011 |
Tanaka N, Chakravarty AK, Maughan B, Shuman S. Novel mechanism of RNA repair by RtcB via sequential 2',3'-cyclic phosphodiesterase and 3'-Phosphate/5'-hydroxyl ligation reactions. The Journal of Biological Chemistry. 286: 43134-43. PMID 22045815 DOI: 10.1074/Jbc.M111.302133 |
0.322 |
|
| 2011 |
Jain R, Poulos MG, Gros J, Chakravarty AK, Shuman S. Substrate specificity and mutational analysis of Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease. Rna (New York, N.Y.). 17: 1336-43. PMID 21610213 DOI: 10.1261/Rna.2722711 |
0.433 |
|
| 2011 |
Samai P, Shuman S. Structure-function analysis of the OB and latch domains of chlorella virus DNA ligase. The Journal of Biological Chemistry. 286: 22642-52. PMID 21527793 DOI: 10.1074/Jbc.M111.245399 |
0.577 |
|
| 2011 |
Simsek D, Furda A, Gao Y, Artus J, Brunet E, Hadjantonakis AK, Van Houten B, Shuman S, McKinnon PJ, Jasin M. Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature. 471: 245-8. PMID 21390132 DOI: 10.1038/Nature09794 |
0.537 |
|
| 2011 |
Samai P, Shuman S. Functional dissection of the DNA interface of the nucleotidyltransferase domain of chlorella virus DNA ligase. The Journal of Biological Chemistry. 286: 13314-26. PMID 21335605 DOI: 10.1074/Jbc.M111.226191 |
0.629 |
|
| 2011 |
Gupta R, Barkan D, Redelman-Sidi G, Shuman S, Glickman MS. Mycobacteria exploit three genetically distinct DNA double-strand break repair pathways. Molecular Microbiology. 79: 316-30. PMID 21219454 DOI: 10.1111/J.1365-2958.2010.07463.X |
0.455 |
|
| 2011 |
Dutta K, Natarajan A, Nair PA, Shuman S, Ghose R. Sequence-specific 1H, 13C and 15N assignments of the phosphoesterase (PE) domain of Pseudomonas aeruginosa DNA ligase D (LigD). Biomolecular Nmr Assignments. 5: 151-5. PMID 21213076 DOI: 10.1007/S12104-010-9289-7 |
0.549 |
|
| 2011 |
Smith P, Nair PA, Das U, Zhu H, Shuman S. Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily. Nucleic Acids Research. 39: 3310-20. PMID 21208981 DOI: 10.1093/Nar/Gkq1163 |
0.503 |
|
| 2011 |
Chakravarty AK, Shuman S. RNA 3'-phosphate cyclase (RtcA) catalyzes ligase-like adenylylation of DNA and RNA 5'-monophosphate ends. The Journal of Biological Chemistry. 286: 4117-22. PMID 21098490 DOI: 10.1074/Jbc.M110.196766 |
0.422 |
|
| 2010 |
Unciuleac MC, Shuman S. Double strand break unwinding and resection by the mycobacterial helicase-nuclease AdnAB in the presence of single strand DNA-binding protein (SSB). The Journal of Biological Chemistry. 285: 34319-29. PMID 20736178 DOI: 10.1074/Jbc.M110.162925 |
0.567 |
|
| 2010 |
Nair PA, Smith P, Shuman S. Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily. Proceedings of the National Academy of Sciences of the United States of America. 107: 12822-7. PMID 20616014 DOI: 10.1073/Pnas.1005830107 |
0.612 |
|
| 2010 |
Patel A, Yakovleva L, Shuman S, Mondragón A. Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site. Structure (London, England : 1993). 18: 725-33. PMID 20541510 DOI: 10.1016/J.Str.2010.03.007 |
0.652 |
|
| 2010 |
Zhu H, Shuman S. Gap filling activities of Pseudomonas DNA ligase D (LigD) polymerase and functional interactions of LigD with the DNA end-binding Ku protein. The Journal of Biological Chemistry. 285: 4815-25. PMID 20018881 DOI: 10.1074/Jbc.M109.073874 |
0.634 |
|
| 2010 |
Jain R, Shuman S. Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. Rna (New York, N.Y.). 16: 316-23. PMID 20007328 DOI: 10.1261/Rna.1926510 |
0.323 |
|
| 2010 |
Wang LK, Shuman S. Mutational analysis of the 5'-OH oligonucleotide phosphate acceptor site of T4 polynucleotide kinase. Nucleic Acids Research. 38: 1304-11. PMID 19966275 DOI: 10.1093/Nar/Gkp1096 |
0.317 |
|
| 2010 |
Unciuleac MC, Shuman S. Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machines Journal of Biological Chemistry. 285: 2632-2641. PMID 19920138 DOI: 10.1074/Jbc.M109.076133 |
0.466 |
|
| 2010 |
Piserchio A, Nair PA, Shuman S, Ghose R. Solution NMR studies of Chlorella virus DNA ligase-adenylate. Journal of Molecular Biology. 395: 291-308. PMID 19913033 DOI: 10.1016/J.Jmb.2009.11.007 |
0.467 |
|
| 2009 |
Piserchio A, Nair PA, Shuman S, Ghose R. Sequence-specific 1H N, 13C, and 15N backbone resonance assignments of the 34 kDa Paramecium bursaria Chlorella virus 1 (PBCV1) DNA ligase. Biomolecular Nmr Assignments. 3: 77-80. PMID 19636951 DOI: 10.1007/S12104-009-9145-9 |
0.478 |
|
| 2009 |
Sinha KM, Unciuleac MC, Glickman MS, Shuman S. AdnAB: A new DSB-resecting motor-nuclease from mycobacteria Genes and Development. 23: 1423-1437. PMID 19470566 DOI: 10.1101/Gad.1805709 |
0.468 |
|
| 2009 |
Shuman S. DNA ligases: Progress and prospects Journal of Biological Chemistry. 284: 17365-17369. PMID 19329793 DOI: 10.1074/Jbc.R900017200 |
0.63 |
|
| 2009 |
Sinha KM, Glickman MS, Shuman S. Mutational analysis of mycobacterium UvrD1 identifies functional groups required for ATP hydrolysis, DNA unwinding, and chemomechanical coupling Biochemistry. 48: 4019-4030. PMID 19317511 DOI: 10.1021/Bi900103D |
0.538 |
|
| 2009 |
Jain R, Shuman S. Characterization of a thermostable archaeal polynucleotide kinase homologous to human Clp1 Rna. 15: 923-931. PMID 19299550 DOI: 10.1261/Rna.1492809 |
0.305 |
|
| 2009 |
Wang LK, Zhu H, Shuman S. Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA). The Journal of Biological Chemistry. 284: 8486-94. PMID 19150981 DOI: 10.1074/Jbc.M808476200 |
0.483 |
|
| 2009 |
Natarajan A, Zhu H, Nair PA, Shuman S, Ghose R. Structure/function Correlations in P. aeruginosa DNA Ligase LigD Biophysical Journal. 96: 58a-59a. DOI: 10.1016/J.Bpj.2008.12.199 |
0.482 |
|
| 2009 |
Piserchio A, Nair PA, Shuman SS, Ghose R. Functional Dynamics in Chlorella virus DNA Ligase Biophysical Journal. 96: 322a. DOI: 10.1016/J.Bpj.2008.12.1614 |
0.552 |
|
| 2008 |
Sinha KM, Stephanou NC, Unciuleac MC, Glickman MS, Shuman S. Domain requirements for DNA unwinding by mycobacterial UvrD2, an essential DNA helicase. Biochemistry. 47: 9355-64. PMID 18702526 DOI: 10.1021/Bi800725Q |
0.462 |
|
| 2008 |
Nandakumar J, Schwer B, Schaffrath R, Shuman S. RNA repair: an antidote to cytotoxic eukaryal RNA damage. Molecular Cell. 31: 278-86. PMID 18657509 DOI: 10.1016/J.Molcel.2008.05.019 |
0.301 |
|
| 2008 |
Wang LK, Nair PA, Shuman S. Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escherichia coli DNA ligase. The Journal of Biological Chemistry. 283: 23343-52. PMID 18515356 DOI: 10.1074/Jbc.M802945200 |
0.452 |
|
| 2008 |
Crut A, Nair PA, Koster DA, Shuman S, Dekker NH. Dynamics of phosphodiester synthesis by DNA ligase. Proceedings of the National Academy of Sciences of the United States of America. 105: 6894-9. PMID 18458338 DOI: 10.1073/Pnas.0800113105 |
0.604 |
|
| 2008 |
Benarroch D, Smith P, Shuman S. Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domain. Structure (London, England : 1993). 16: 501-12. PMID 18400173 DOI: 10.1016/J.Str.2008.01.009 |
0.447 |
|
| 2008 |
Yakovleva L, Chen S, Hecht SM, Shuman S. Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provides insights to cleavage site recognition and transesterification chemistry. The Journal of Biological Chemistry. 283: 16093-103. PMID 18367446 DOI: 10.1074/Jbc.M801595200 |
0.604 |
|
| 2008 |
Aniukwu J, Glickman MS, Shuman S. The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends. Genes & Development. 22: 512-27. PMID 18281464 DOI: 10.1101/Gad.1631908 |
0.532 |
|
| 2008 |
Zhu H, Shuman S. Bacterial nonhomologous end joining ligases preferentially seal breaks with a 3′-OH monoribonucleotide Journal of Biological Chemistry. 283: 8331-8339. PMID 18203718 DOI: 10.1074/Jbc.M705476200 |
0.542 |
|
| 2007 |
Keppetipola N, Shuman S. Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase. Nucleic Acids Research. 35: 7721-32. PMID 17986465 DOI: 10.1093/Nar/Gkm868 |
0.319 |
|
| 2007 |
Shuman S, Glickman MS. Bacterial DNA repair by non-homologous end joining. Nature Reviews. Microbiology. 5: 852-61. PMID 17938628 DOI: 10.1038/Nrmicro1768 |
0.538 |
|
| 2007 |
Stephanou NC, Gao F, Bongiorno P, Ehrt S, Schnappinger D, Shuman S, Glickman MS. Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks. Journal of Bacteriology. 189: 5237-46. PMID 17496093 DOI: 10.1128/Jb.00332-07 |
0.404 |
|
| 2007 |
Keppetipola N, Nandakumar J, Shuman S. Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme. Nucleic Acids Research. 35: 3624-30. PMID 17488852 DOI: 10.1093/Nar/Gkm110 |
0.335 |
|
| 2007 |
Zhu H, Shuman S. Characterization of Agrobacterium tumefaciens DNA ligases C and D Nucleic Acids Research. 35: 3631-3645. PMID 17488851 DOI: 10.1093/Nar/Gkm145 |
0.559 |
|
| 2007 |
Nandakumar J, Nair PA, Shuman S. Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate. Molecular Cell. 26: 257-71. PMID 17466627 DOI: 10.1016/J.Molcel.2007.02.026 |
0.555 |
|
| 2007 |
Sinha KM, Stephanou NC, Gao F, Glickman MS, Shuman S. Mycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repair. The Journal of Biological Chemistry. 282: 15114-25. PMID 17376770 DOI: 10.1074/Jbc.M701167200 |
0.592 |
|
| 2007 |
Tian L, Shuman S. Vaccinia topoisomerase mutants illuminate roles for Phe59, Gly73, Gln69 and Phe215. Virology. 359: 466-76. PMID 17059840 DOI: 10.1016/J.Virol.2006.08.056 |
0.484 |
|
| 2007 |
Benarroch D, Claverie JM, Raoult D, Shuman S. Characterization of mimivirus DNA topoisomerase IB suggests horizontal gene transfer between eukaryal viruses and bacteria. Journal of Virology. 80: 314-21. PMID 16352556 DOI: 10.1128/Jvi.80.1.314-321.2006 |
0.496 |
|
| 2006 |
Nandakumar J, Shuman S, Lima CD. RNA ligase structures reveal the basis for RNA specificity and conformational changes that drive ligation forward. Cell. 127: 71-84. PMID 17018278 DOI: 10.1016/J.Cell.2006.08.038 |
0.377 |
|
| 2006 |
Yakovleva L, Lai J, Kool ET, Shuman S. Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase. The Journal of Biological Chemistry. 281: 35914-21. PMID 17005552 DOI: 10.1074/Jbc.M608349200 |
0.571 |
|
| 2006 |
Benarroch D, Shuman S. Characterization of mimivirus NAD+-dependent DNA ligase Virology. 353: 133-143. PMID 16844179 DOI: 10.1016/J.Virol.2006.04.032 |
0.596 |
|
| 2006 |
Yakovleva L, Shuman S. Nucleotide misincorporation, 3′-mismatch extension, and responses to abasic sites and DNA adducts by the polymerase component of bacterial DNA ligase D Journal of Biological Chemistry. 281: 25026-25040. PMID 16816388 DOI: 10.1074/Jbc.M603302200 |
0.584 |
|
| 2006 |
Yakovleva L, Handy CJ, Yagi H, Sayer JM, Jerina DM, Shuman S. Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III. Biochemistry. 45: 7644-53. PMID 16768460 DOI: 10.1021/Bi060158H |
0.621 |
|
| 2006 |
Zhu H, Shuman S. Substrate specificity and structure-function analysis of the 3′-phosphoesterase component of the bacterial NHEJ protein, DNA ligase D Journal of Biological Chemistry. 281: 13873-13881. PMID 16540477 DOI: 10.1074/Jbc.M600055200 |
0.44 |
|
| 2006 |
Akey D, Martins A, Aniukwu J, Glickman MS, Shuman S, Berger JM. Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D. The Journal of Biological Chemistry. 281: 13412-23. PMID 16476729 DOI: 10.1074/Jbc.M513550200 |
0.551 |
|
| 2006 |
Zhu H, Nandakumar J, Aniukwu J, Wang LK, Glickman MS, Lima CD, Shuman S. Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D. Proceedings of the National Academy of Sciences of the United States of America. 103: 1711-6. PMID 16446439 DOI: 10.1073/Pnas.0509083103 |
0.583 |
|
| 2006 |
Patel A, Shuman S, Mondragón A. Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA. The Journal of Biological Chemistry. 281: 6030-7. PMID 16368685 DOI: 10.1074/Jbc.M512332200 |
0.596 |
|
| 2006 |
Keppetipola N, Shuman S. Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase. Rna (New York, N.Y.). 12: 73-82. PMID 16301605 DOI: 10.1261/Rna.2196406 |
0.333 |
|
| 2005 |
Khalid MF, Damha MJ, Shuman S, Schwer B. Structure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase. Nucleic Acids Research. 33: 6349-60. PMID 16275784 DOI: 10.1093/Nar/Gki934 |
0.331 |
|
| 2005 |
Moreno-Herrero F, Holtzer L, Koster DA, Shuman S, Dekker C, Dekker NH. Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion Nucleic Acids Research. 33: 5945-5953. PMID 16237128 DOI: 10.1093/Nar/Gki906 |
0.584 |
|
| 2005 |
Keppetipola N, Shuman S. Characterization of a thermophilic ATP-dependent DNA ligase from the euryarchaeon Pyrococcus horikoshii. Journal of Bacteriology. 187: 6902-8. PMID 16199559 DOI: 10.1128/Jb.187.20.6902-6908.2005 |
0.514 |
|
| 2005 |
Zhu H, Wang LK, Shuman S. Essential constituents of the 3'-phosphoesterase domain of bacterial DNA ligase D, a nonhomologous end-joining enzyme. The Journal of Biological Chemistry. 280: 33707-15. PMID 16046407 DOI: 10.1074/Jbc.M506838200 |
0.47 |
|
| 2005 |
Martins A, Shuman S. An end-healing enzyme from Clostridium thermocellum with 5′ kinase, 2′,3′ phosphatase, and adenylyltransferase activities Rna. 11: 1271-1280. PMID 15987807 DOI: 10.1261/Rna.2690505 |
0.436 |
|
| 2005 |
Li KW, Shuman S. Structure-function analysis of yeast tRNA ligase Rna. 11: 966-975. PMID 15923379 DOI: 10.1261/Rna.2170305 |
0.34 |
|
| 2005 |
Zhu H, Shuman S. Novel 3′-ribonuclease and 3′-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase D Journal of Biological Chemistry. 280: 25973-25981. PMID 15897197 DOI: 10.1074/Jbc.M504002200 |
0.544 |
|
| 2005 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Mechanistic plasticity of DNA topoisomerase IB: phosphate electrostatics dictate the need for a catalytic arginine. Structure (London, England : 1993). 13: 513-20. PMID 15837190 DOI: 10.1016/J.Str.2005.02.001 |
0.586 |
|
| 2005 |
Koster DA, Croquette V, Dekker C, Shuman S, Dekker NH. Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB. Nature. 434: 671-4. PMID 15800630 DOI: 10.1038/Nature03395 |
0.597 |
|
| 2005 |
Gong C, Bongiorno P, Martins A, Stephanou NC, Zhu H, Shuman S, Glickman MS. Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C. Nature Structural & Molecular Biology. 12: 304-12. PMID 15778718 DOI: 10.1038/Nsmb915 |
0.551 |
|
| 2005 |
Zhu H, Shuman S. Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA) Journal of Biological Chemistry. 280: 12137-12144. PMID 15671015 DOI: 10.1074/Jbc.M413685200 |
0.418 |
|
| 2005 |
Zhu H, Shuman S. A primer-dependent polymerase function of Pseudomonas aeruginosa ATP-dependent DNA ligase (LigD) Journal of Biological Chemistry. 280: 418-427. PMID 15520014 DOI: 10.1074/Jbc.M410110200 |
0.628 |
|
| 2004 |
Shuman S, Lima CD. The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases. Current Opinion in Structural Biology. 14: 757-64. PMID 15582400 DOI: 10.1016/J.Sbi.2004.10.006 |
0.485 |
|
| 2004 |
Nandakumar J, Shuman S. How an RNA ligase discriminates RNA versus DNA damage. Molecular Cell. 16: 211-21. PMID 15494308 DOI: 10.1016/J.Molcel.2004.09.022 |
0.409 |
|
| 2004 |
Martins A, Shuman S. An RNA ligase from Deinococcus radiodurans Journal of Biological Chemistry. 279: 50654-50661. PMID 15333634 DOI: 10.1074/Jbc.M407657200 |
0.357 |
|
| 2004 |
Shuman S. NAD+ specificity of bacterial DNA ligase revealed Structure. 12: 1335-1336. PMID 15296724 DOI: 10.1016/J.Str.2004.07.002 |
0.569 |
|
| 2004 |
Nandakumar J, Ho CK, Lima CD, Shuman S. RNA substrate specificity and structure-guided mutational analysis of bacteriophage T4 RNA ligase 2. The Journal of Biological Chemistry. 279: 31337-47. PMID 15084599 DOI: 10.1074/Jbc.M402394200 |
0.322 |
|
| 2004 |
Zhu H, Yin S, Shuman S. Characterization of polynucleotide kinase/phosphatase enzymes from Mycobacteriophages omega and Cjw1 and vibriophage KVP40. The Journal of Biological Chemistry. 279: 26358-69. PMID 15056675 DOI: 10.1074/Jbc.M403200200 |
0.361 |
|
| 2004 |
Yakovleva L, Handy CJ, Sayer JM, Pirrung M, Jerina DM, Shuman S. Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase. The Journal of Biological Chemistry. 279: 23335-42. PMID 15044474 DOI: 10.1074/Jbc.M401203200 |
0.569 |
|
| 2004 |
Gong C, Martins A, Bongiorno P, Glickman M, Shuman S. Biochemical and genetic analysis of the four DNA ligases of mycobacteria. The Journal of Biological Chemistry. 279: 20594-606. PMID 14985346 DOI: 10.1074/Jbc.M401841200 |
0.494 |
|
| 2004 |
Yin S, Kiong Ho C, Miller ES, Shuman S. Characterization of bacteriophage KVP40 and T4 RNA ligase 2. Virology. 319: 141-51. PMID 14967495 DOI: 10.1016/J.Virol.2003.10.037 |
0.301 |
|
| 2004 |
Ho CK, Wang LK, Lima CD, Shuman S. Structure and mechanism of RNA ligase. Structure (London, England : 1993). 12: 327-39. PMID 14962393 DOI: 10.1016/J.Str.2004.01.011 |
0.318 |
|
| 2004 |
Liao S, Mao C, Birktoft JJ, Shuman S, Seeman NC. Resolution of undistorted symmetric immobile DNA junctions by vaccinia topoisomerase I. Biochemistry. 43: 1520-31. PMID 14769028 DOI: 10.1021/Bi0358061 |
0.557 |
|
| 2004 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB. Structure (London, England : 1993). 12: 31-40. PMID 14725763 DOI: 10.1016/J.Str.2003.11.025 |
0.532 |
|
| 2004 |
Odell M, Malinina L, Sriskanda V, Teplova M, Shuman S. Analysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediate. Nucleic Acids Research. 31: 5090-100. PMID 12930960 DOI: 10.1093/Nar/Gkg665 |
0.576 |
|
| 2003 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Guarding the genome: electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB. Molecular Cell. 12: 199-208. PMID 12887905 DOI: 10.1016/S1097-2765(03)00263-6 |
0.609 |
|
| 2003 |
Sawaya R, Shuman S. Mutational analysis of the guanylyltransferase component of Mammalian mRNA capping enzyme. Biochemistry. 42: 8240-9. PMID 12846573 DOI: 10.1021/Bi034396D |
0.323 |
|
| 2003 |
Wang LK, Ho CK, Pei Y, Shuman S. Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction. The Journal of Biological Chemistry. 278: 29454-62. PMID 12766156 DOI: 10.1074/Jbc.M304320200 |
0.346 |
|
| 2003 |
Yin S, Ho CK, Shuman S. Structure-function analysis of T4 RNA ligase 2. The Journal of Biological Chemistry. 278: 17601-8. PMID 12611899 DOI: 10.1074/Jbc.M300817200 |
0.386 |
|
| 2003 |
Tian L, Sayer JM, Kroth H, Kalena G, Jerina DM, Shuman S. Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove. The Journal of Biological Chemistry. 278: 9905-11. PMID 12524450 DOI: 10.1074/Jbc.M212468200 |
0.576 |
|
| 2002 |
Wang LK, Lima CD, Shuman S. Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme. The Embo Journal. 21: 3873-80. PMID 12110598 DOI: 10.1093/Emboj/Cdf397 |
0.357 |
|
| 2002 |
Gong C, Shuman S. Chlorella virus RNA triphosphatase. Mutational analysis and mechanism of inhibition by tripolyphosphate. The Journal of Biological Chemistry. 277: 15317-24. PMID 11844801 DOI: 10.1074/Jbc.M200532200 |
0.332 |
|
| 2002 |
Sriskanda V, Shuman S. Role of nucleotidyltransferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase Nucleic Acids Research. 30: 903-911. PMID 11842101 DOI: 10.1093/Nar/30.4.903 |
0.622 |
|
| 2002 |
Krogh BO, Shuman S. A poxvirus-like type IB topoisomerase family in bacteria Proceedings of the National Academy of Sciences of the United States of America. 99: 1853-1858. PMID 11830640 DOI: 10.1073/Pnas.032613199 |
0.534 |
|
| 2002 |
Sriskanda V, Shuman S. Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+ Journal of Biological Chemistry. 277: 9695-9700. PMID 11781321 DOI: 10.1074/Jbc.M111164200 |
0.584 |
|
| 2002 |
Krogh BO, Shuman S. Proton relay mechanism of general acid catalysis by DNA topoisomerase IB Journal of Biological Chemistry. 277: 5711-5714. PMID 11756402 DOI: 10.1074/Jbc.C100681200 |
0.53 |
|
| 2002 |
Sriskanda V, Shuman S. Role of nucleotidyl transferase motif V in strand joining by Chlorella virus DNA ligase Journal of Biological Chemistry. 277: 9661-9667. PMID 11751916 DOI: 10.1074/Jbc.M110613200 |
0.624 |
|
| 2002 |
Odell M, Sriskanda V, Shuman S, Nikolov DB. Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining. Molecular Cell. 6: 1183-93. PMID 11106756 DOI: 10.1016/S1097-2765(00)00115-5 |
0.525 |
|
| 2001 |
Sriskanda V, Shuman S. A second NAD+-dependent DNA ligase (LigB) in Escherichia coli Nucleic Acids Research. 29: 4930-4934. PMID 11812821 DOI: 10.1093/Nar/29.24.4930 |
0.619 |
|
| 2001 |
Sriskanda V, Moyer RW, Shuman S. NAD+-dependent DNA ligase encoded by a eukaryotic virus. The Journal of Biological Chemistry. 276: 36100-9. PMID 11459847 DOI: 10.1074/jbc.M105643200 |
0.469 |
|
| 2001 |
Krogh BO, Shuman S. Vaccinia topoisomerase mutants illuminate conformational changes during closure of the protein clamp and assembly of a functional active site. The Journal of Biological Chemistry. 276: 36091-9. PMID 11441004 DOI: 10.1074/Jbc.M102609200 |
0.463 |
|
| 2001 |
Krogh BO, Claeboe CD, Hecht SM, Shuman S. Effect of 2'-5' phosphodiesters on DNA transesterification by vaccinia topoisomerase. The Journal of Biological Chemistry. 276: 20907-12. PMID 11399773 DOI: 10.1074/Jbc.M102312200 |
0.661 |
|
| 2001 |
Shuman S. Analysis of topoisomerase-DNA interactions by electrophoretic mobility shift assay Methods in Molecular Biology (Clifton, N.J.). 95: 65-74. PMID 11089220 DOI: 10.1385/1-59259-057-8:65 |
0.462 |
|
| 2000 |
Cheng C, Shuman S. Recombinogenic flap ligation pathway for intrinsic repair of topoisomerase IB-induced double-strand breaks. Molecular and Cellular Biology. 20: 8059-68. PMID 11027276 DOI: 10.1128/Mcb.20.21.8059-8068.2000 |
0.777 |
|
| 2000 |
Martins A, Shuman S. Mechanism of phosphoanhydride cleavage by baculovirus phosphatase Journal of Biological Chemistry. 275: 35070-35076. PMID 10954717 DOI: 10.1074/Jbc.M005748200 |
0.309 |
|
| 2000 |
Woodfield G, Cheng C, Shuman S, Burgin AB. Vaccinia topoisomerase and Cre recombinase catalyze direct ligation of activated DNA substrates containing a 3'-para-nitrophenyl phosphate ester. Nucleic Acids Research. 28: 3323-31. PMID 10954601 DOI: 10.1093/nar/28.17.3323 |
0.795 |
|
| 2000 |
Krogh BO, Shuman S. Catalytic mechanism of DNA topoisomerase IB. Molecular Cell. 5: 1035-41. PMID 10911997 DOI: 10.1016/S1097-2765(00)80268-3 |
0.566 |
|
| 2000 |
Sekiguchi J, Cheng C, Shuman S. Resolution of a Holliday junction by vaccinia topoisomerase requires a spacer DNA segment 3' of the CCCTT/ cleavage sites. Nucleic Acids Research. 28: 2658-63. PMID 10908320 DOI: 10.1093/Nar/28.14.2658 |
0.693 |
|
| 2000 |
Klemm M, Cheng C, Cassell G, Shuman S, Segall AM. Peptide inhibitors of DNA cleavage by tyrosine recombinases and topoisomerases Journal of Molecular Biology. 299: 1203-1216. PMID 10873446 DOI: 10.1006/Jmbi.2000.3829 |
0.732 |
|
| 2000 |
Sriskanda V, Kelman Z, Hurwitz J, Shuman S. Characterization of an ATP-dependent DNA ligase from the the thermophilic archaeon Methanobacterium thermoautotrophicum Nucleic Acids Research. 28: 2221-2228. PMID 10871342 DOI: 10.1093/Nar/28.11.2221 |
0.589 |
|
| 2000 |
Krogh BO, Shuman S. DNA strand transfer catalyzed by vaccinia topoisomerase: peroxidolysis and hydroxylaminolysis of the covalent protein-DNA intermediate. Biochemistry. 39: 6422-32. PMID 10828956 DOI: 10.1021/Bi000184U |
0.611 |
|
| 2000 |
Stivers JT, Jagadeesh GJ, Nawrot B, Stec WJ, Shuman S. Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase. Biochemistry. 39: 5561-72. PMID 10820030 DOI: 10.1021/Bi992429C |
0.462 |
|
| 2000 |
Cheng C, Shuman S. DNA strand transfer catalyzed by vaccinia topoisomerase: ligation of DNAs containing a 3' mononucleotide overhang. Nucleic Acids Research. 28: 1893-8. PMID 10756188 DOI: 10.1093/Nar/28.9.1893 |
0.785 |
|
| 1999 |
Cheng C, Shuman S. Site-specific DNA transesterification by vaccinia topoisomerase: role of specific phosphates and nucleosides. Biochemistry. 38: 16599-612. PMID 10600122 DOI: 10.1021/Bi992001D |
0.775 |
|
| 1999 |
Krogh BO, Cheng C, Burgin A, Shuman S. Melanoplus sanguinipes entomopoxvirus DNA topoisomerase: site-specific DNA transesterification and effects of 5'-bridging phosphorothiolates. Virology. 264: 441-51. PMID 10562506 DOI: 10.1006/Viro.1999.0022 |
0.778 |
|
| 1999 |
Pei Y, Ho CK, Schwer B, Shuman S. Mutational analyses of yeast RNA triphosphatases highlight a common mechanism of metal-dependent NTP hydrolysis and a means of targeting enzymes to Pre-mRNAs in vivo by fusion to the guanylyltransferase component of the capping apparatus Journal of Biological Chemistry. 274: 28865-28874. PMID 10506129 DOI: 10.1074/Jbc.274.41.28865 |
0.337 |
|
| 1999 |
Sriskanda V, Schwer B, Ho KC, Shuman S. Mutational analysis of Escherichia coli DNA ligase identifies amino acids required for nick-ligation in vitro and for in vivo complementation of the growth of yeast cells deleted for CDC9 and LIG4 Nucleic Acids Research. 27: 3953-3963. PMID 10497258 DOI: 10.1093/Nar/27.20.3953 |
0.548 |
|
| 1999 |
Odell M, Shuman S. Footprinting of Chlorella virus DNA ligase bound at a nick in duplex DNA Journal of Biological Chemistry. 274: 14032-14039. PMID 10318816 DOI: 10.1074/Jbc.274.20.14032 |
0.644 |
|
| 1999 |
Martins A, Gross CH, Shuman S. Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase I, a DNA-dependent ATPase of the DExH box family. Journal of Virology. 73: 1302-8. PMID 9882335 DOI: 10.1128/Jvi.73.2.1302-1308.1999 |
0.393 |
|
| 1999 |
Ho CK, Pei Y, Shuman S. Yeast and viral RNA 5' triphosphatases comprise a new nucleoside triphosphatase family. The Journal of Biological Chemistry. 273: 34151-6. PMID 9852075 DOI: 10.1074/Jbc.273.51.34151 |
0.349 |
|
| 1998 |
Sriskanda V, Shuman S. Mutational analysis of Chlorella virus DNA ligase: Catalytic roles of domain I and motif VI Nucleic Acids Research. 26: 4618-4625. PMID 9753729 DOI: 10.1093/Nar/26.20.4618 |
0.533 |
|
| 1998 |
Shuman S. Vaccinia virus DNA topoisomerase: A model eukaryotic type IB enzyme Biochimica Et Biophysica Acta - Gene Structure and Expression. 1400: 321-337. PMID 9748643 DOI: 10.1016/S0167-4781(98)00144-4 |
0.631 |
|
| 1998 |
Gross CH, Shuman S. Characterization of a baculovirus-encoded RNA 5'-triphosphatase Journal of Virology. 72: 7057-7063. PMID 9696798 DOI: 10.1128/Jvi.72.9.7057-7063.1998 |
0.317 |
|
| 1998 |
Sriskanda V, Shuman S. Specificity and fidelity of strand joining by Chlorella virus DNA ligase Nucleic Acids Research. 26: 3536-3541. PMID 9671815 DOI: 10.1093/Nar/26.15.3536 |
0.59 |
|
| 1998 |
Shuman S. Polynucleotide ligase activity of eukaryotic topoisomerase I Molecular Cell. 1: 741-748. PMID 9660957 DOI: 10.1016/S1097-2765(00)80073-8 |
0.478 |
|
| 1998 |
Cheng C, Shuman S. A catalytic domain of eukaryotic DNA topoisomerase I. The Journal of Biological Chemistry. 273: 11589-95. PMID 9565576 DOI: 10.1074/Jbc.273.19.11589 |
0.794 |
|
| 1998 |
Cheng C, Kussie P, Pavletich N, Shuman S. Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases Cell. 92: 841-850. PMID 9529259 DOI: 10.1016/S0092-8674(00)81411-7 |
0.736 |
|
| 1998 |
Deng L, Shuman S. Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination Genes and Development. 12: 538-546. PMID 9472022 DOI: 10.1101/Gad.12.4.538 |
0.314 |
|
| 1998 |
Sriskanda V, Shuman S. Chlorella virus DNA ligase: Nick recognition and mutational analysis Nucleic Acids Research. 26: 525-531. PMID 9421510 DOI: 10.1093/Nar/26.2.502 |
0.664 |
|
| 1998 |
Wittschieben J, Petersen BO, Shuman S. Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease. Nucleic Acids Research. 26: 490-6. PMID 9421505 DOI: 10.1093/Nar/26.2.490 |
0.602 |
|
| 1997 |
Sekiguchi J, Shuman S. Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I Molecular Cell. 1: 89-97. PMID 9659906 DOI: 10.1016/S1097-2765(00)80010-6 |
0.581 |
|
| 1997 |
Sekiguchi J, Shuman S. Nick sensing by vaccinia virus DNA ligase requires a 5' phosphate at the nick and occupancy of the adenylate binding site on the enzyme Journal of Virology. 71: 9679-9684. PMID 9371633 DOI: 10.1128/Jvi.71.12.9679-9684.1997 |
0.656 |
|
| 1997 |
Sekiguchi J, Shuman S. Novobiocin inhibits vaccinia virus replication by blocking virus assembly Virology. 235: 129-137. PMID 9300044 DOI: 10.1006/Viro.1997.8684 |
0.36 |
|
| 1997 |
Sekiguchi J, Shuman S. Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding Nucleic Acids Research. 25: 3649-3656. PMID 9278486 DOI: 10.1093/Nar/25.18.3649 |
0.644 |
|
| 1997 |
Wang SP, Deng L, Ho CK, Shuman S. Phylogeny of mRNA capping enzymes. Proceedings of the National Academy of Sciences of the United States of America. 94: 9573-8. PMID 9275164 DOI: 10.1073/Pnas.94.18.9573 |
0.378 |
|
| 1997 |
Wittschieben J, Shuman S. Mechanism of DNA transesterification by vaccinia topoisomerase: Catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167 Nucleic Acids Research. 25: 3001-3008. PMID 9224599 DOI: 10.1093/Nar/25.15.3001 |
0.601 |
|
| 1997 |
Sekiguchi J, Shuman S. Ligation of RNA-containing duplexes by vaccinia DNA ligase Biochemistry. 36: 9073-9079. PMID 9220997 DOI: 10.1021/Bi970705M |
0.568 |
|
| 1997 |
Wang LK, Wittschieben J, Shuman S. Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage. Biochemistry. 36: 7944-50. PMID 9201940 DOI: 10.1021/Bi970498Q |
0.65 |
|
| 1997 |
Sekiguchi J, Cheng C, Shuman S. Kinetic analysis of DNA and RNA strand transfer reactions catalyzed by vaccinia topoisomerase. The Journal of Biological Chemistry. 272: 15721-8. PMID 9188465 DOI: 10.1074/Jbc.272.25.15721 |
0.782 |
|
| 1997 |
Petersen B, Shuman S. DNA strand transfer reactions catalyzed by vaccinia topoisomerase: Hydrolysis and glycerololysis of the covalent protein-DNA intermediate Nucleic Acids Research. 25: 2091-2097. PMID 9153307 DOI: 10.1093/Nar/25.11.2091 |
0.649 |
|
| 1997 |
Petersen BO, Hall RL, Moyer RW, Shuman S. Characterization of a DNA topoisomerase encoded by Amsacta moore entomopoxvirus. Virology. 230: 197-206. PMID 9143275 DOI: 10.1006/Viro.1997.8495 |
0.577 |
|
| 1997 |
Wang LK, Shuman S. Deletions at the carboxyl terminus of vaccinia DNA topoisomerase affect DNA binding and enhance distributivity in DNA relaxation Biochemistry. 36: 3909-3916. PMID 9092821 DOI: 10.1021/Bi962754P |
0.648 |
|
| 1997 |
Cheng C, Wang LK, Sekiguchi J, Shuman S. Mutational analysis of 39 residues of vaccinia DNA topoisomerase identifies Lys-220, Arg-223, and Asn-228 as important for covalent catalysis. The Journal of Biological Chemistry. 272: 8263-9. PMID 9079646 DOI: 10.1074/Jbc.272.13.8263 |
0.751 |
|
| 1997 |
Cheng C, Shuman S. Characterization of an ATP-dependent DNA ligase encoded by Haemophilus influenzae. Nucleic Acids Research. 25: 1369-74. PMID 9060431 DOI: 10.1093/Nar/25.7.1369 |
0.762 |
|
| 1997 |
Ho CK, Van Etten JL, Shuman S. Characterization of an ATP-dependent DNA ligase encoded by Chlorella virus PBCV-1. Journal of Virology. 71: 1931-7. PMID 9032324 DOI: 10.1128/Jvi.71.3.1931-1937.1997 |
0.629 |
|
| 1997 |
Petersen B, Shuman S. Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes Journal of Biological Chemistry. 272: 3891-3896. PMID 9020090 DOI: 10.1074/Jbc.272.7.3891 |
0.545 |
|
| 1997 |
Sekiguchi J, Shuman S. Domain structure of vaccinia DNA ligase Nucleic Acids Research. 25: 727-734. PMID 9016621 DOI: 10.1093/Nar/25.4.727 |
0.492 |
|
| 1996 |
Gross CH, Shuman S. Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription Journal of Virology. 70: 8549-8557. PMID 8970979 |
0.35 |
|
| 1996 |
Petersen BO, Wittschieben J, Shuman S. Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium. Journal of Molecular Biology. 263: 181-95. PMID 8913300 DOI: 10.1006/Jmbi.1996.0568 |
0.451 |
|
| 1996 |
Shuman S. Closing the gap on DNA ligase Structure. 4: 653-656. PMID 8805556 DOI: 10.1016/S0969-2126(96)00070-6 |
0.501 |
|
| 1996 |
Ho CK, Van Etten JL, Shuman S. Expression and characterization of an RNA capping enzyme encoded by Chlorella virus PBCV-1. Journal of Virology. 70: 6658-64. PMID 8794301 DOI: 10.1128/Jvi.70.10.6658-6664.1996 |
0.333 |
|
| 1996 |
Sekiguchi J, Shuman S. Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond Journal of Biological Chemistry. 271: 19436-19442. PMID 8702632 DOI: 10.1074/Jbc.271.32.19436 |
0.589 |
|
| 1996 |
Sekiguchi J, Shuman S. Identification of contacts between topoisomerase I and its target DNA by site-specific photocrosslinking Embo Journal. 15: 3448-3457. PMID 8670847 DOI: 10.1002/J.1460-2075.1996.Tb00711.X |
0.622 |
|
| 1996 |
Gross CH, Shuman S. Vaccinia virus RNA helicase: Nucleic acid specificity in duplex unwinding Journal of Virology. 70: 2615-2619. PMID 8642695 |
0.492 |
|
| 1996 |
Ho CK, Shuman S. Physical and functional characterization of the double-stranded RNA binding protein encoded by the vaccinia virus E3 gene Virology. 217: 272-284. PMID 8599212 DOI: 10.1006/Viro.1996.0114 |
0.306 |
|
| 1996 |
Sekiguchi J, Seeman NC, Shuman S. Resolution of Holliday junctions by eukaryotic DNA topoisomerase I. Proceedings of the National Academy of Sciences of the United States of America. 93: 785-9. PMID 8570635 DOI: 10.1073/Pnas.93.2.785 |
0.583 |
|
| 1996 |
Sekiguchi J, Stivers JT, Mildvan AS, Shuman S. Mechanism of inhibition of vaccinia DNA topoisomerase by novobiocin and coumermycin. The Journal of Biological Chemistry. 271: 2313-22. PMID 8567695 DOI: 10.1074/Jbc.271.4.2313 |
0.519 |
|
| 1995 |
Shuman S, Schwer B. RNA capping enzyme and DNA ligase: A superfamily of covalent nucleotidyl transferases Molecular Microbiology. 17: 405-410. PMID 8559059 DOI: 10.1111/J.1365-2958.1995.Mmi_17030405.X |
0.466 |
|
| 1995 |
Shuman S. Vaccinia virus DNA ligase: Specificity, fidelity, and inhibition Biochemistry. 34: 16138-16147. PMID 8519771 DOI: 10.1021/Bi00049A029 |
0.667 |
|
| 1995 |
Sekiguchi J, Shuman S. Proteolytic footprinting of vaccinia topoisomerase bound to DNA Journal of Biological Chemistry. 270: 11636-11645. PMID 7744804 DOI: 10.1074/Jbc.270.19.11636 |
0.606 |
|
| 1995 |
Gross CH, Shuman S. Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase Journal of Virology. 69: 4727-4736. PMID 7609038 |
0.308 |
|
| 1995 |
Cong P, Shuman S. Mutational analysis of mRNA capping enzyme identifies amino acids involved in GTP binding, enzyme-guanylate formation, and GMP transfer to RNA Molecular and Cellular Biology. 15: 6222-6231. PMID 7565775 DOI: 10.1128/Mcb.15.11.6222 |
0.367 |
|
| 1994 |
Stivers JT, Shuman S, Mildvan AS. Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry. 33: 327-39. PMID 8286354 DOI: 10.1021/Bi00167A043 |
0.603 |
|
| 1994 |
Schwer B, Shuman S. Mutational analysis of yeast mRNA capping enzyme Proceedings of the National Academy of Sciences of the United States of America. 91: 4328-4332. PMID 8183907 DOI: 10.1073/Pnas.91.10.4328 |
0.393 |
|
| 1994 |
Shuman S, Liu Y, Schwer B. Covalent catalysis in nucleotidyl transfer reactions: Essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases Proceedings of the National Academy of Sciences of the United States of America. 91: 12046-12050. PMID 7991582 DOI: 10.1073/Pnas.91.25.12046 |
0.357 |
|
| 1994 |
Stivers JT, Shuman S, Mildvan AS. Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step. Biochemistry. 33: 15449-58. PMID 7803409 DOI: 10.1021/Bi00255A027 |
0.371 |
|
| 1992 |
Hagler J, Shuman S. Structural analysis of ternary complexes of vaccinia RNA polymerase Proceedings of the National Academy of Sciences of the United States of America. 89: 10099-10103. PMID 1438198 |
0.509 |
|
| 1992 |
Hagler J, Shuman S. Ternary complex formation by vaccinia virus RNA polymerase at an early viral promoter: Analysis by native gel electrophoresis Journal of Virology. 66: 2982-2989. PMID 1373199 |
0.39 |
|
| 1991 |
Shuman S. Recombination mediated by vaccinia virus DNA topoisomerase I in Escherichia coli is sequence specific Proceedings of the National Academy of Sciences of the United States of America. 88: 10104-10108. PMID 1658796 DOI: 10.1073/Pnas.88.22.10104 |
0.637 |
|
| 1990 |
Morham SG, Shuman S. Phenotypic selection and characterization of mutant alleles of a eukaryotic DNA topoisomerase I Genes and Development. 4: 515-524. PMID 2163340 |
0.375 |
|
| 1989 |
Shuman S, Kane EM, Morham SG. Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I. Proceedings of the National Academy of Sciences of the United States of America. 86: 9793-7. PMID 2557629 DOI: 10.1073/Pnas.86.24.9793 |
0.607 |
|
| 1989 |
Shuman S. Vaccinia DNA topoisomerase I promotes illegitimate recombination in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 86: 3489-3493. PMID 2542933 DOI: 10.1073/Pnas.86.10.3489 |
0.543 |
|
| 1989 |
Shuman S, Golder M, Moss B. Insertional mutagenesis of the vaccinia virus gene encoding a type I DNA topoisomerase: evidence that the gene is essential for virus growth. Virology. 170: 302-6. PMID 2541548 DOI: 10.1016/0042-6822(89)90384-X |
0.318 |
|
| 1987 |
Shuman S, Moss B. Identification of a vaccinia virus gene encoding a type I DNA topoisomerase Proceedings of the National Academy of Sciences of the United States of America. 84: 7478-7482. PMID 2823264 DOI: 10.1073/Pnas.84.21.7478 |
0.374 |
|
| Show low-probability matches. |