Gary Siuzdak - Publications

Affiliations: 
Center for Metabolomics and Mass Spectrometry Scripps Research Institute, La Jolla, La Jolla, CA, United States 

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Thorgersen MP, Xue J, Majumder ELW, Trotter VV, Ge X, Poole FL, Owens TK, Lui LM, Nielsen TN, Arkin AP, Deutschbauer AM, Siuzdak G, Adams MWW. Deciphering Microbial Metal Toxicity Responses using RB-TnSeq and Activity-Based Metabolomics. Applied and Environmental Microbiology. AEM0103721. PMID 34432491 DOI: 10.1128/AEM.01037-21  1
2021 Xue J, Derks RJE, Webb B, Billings EM, Aisporna A, Giera M, Siuzdak G. Single Quadrupole Multiple Fragment Ion Monitoring Quantitative Mass Spectrometry. Analytical Chemistry. PMID 34313111 DOI: 10.1021/acs.analchem.1c01246  1
2021 Alseekh S, Aharoni A, Brotman Y, Contrepois K, D'Auria J, Ewald J, C Ewald J, Fraser PD, Giavalisco P, Hall RD, Heinemann M, Link H, Luo J, Neumann S, Nielsen J, ... ... Siuzdak G, et al. Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices. Nature Methods. 18: 747-756. PMID 34239102 DOI: 10.1038/s41592-021-01197-1  1
2021 Otwell AE, Carr AV, Majumder ELW, Ruiz MK, Wilpiszeski RL, Hoang LT, Webb B, Turkarslan S, Gibbons SM, Elias DA, Stahl DA, Siuzdak G, Baliga NS. Sulfur Metabolites Play Key System-Level Roles in Modulating Denitrification. Msystems. 6. PMID 33563788 DOI: 10.1128/mSystems.01025-20  1
2021 Majumder EL, Billings EM, Benton HP, Martin RL, Palermo A, Guijas C, Rinschen MM, Domingo-Almenara X, Montenegro-Burke JR, Tagtow BA, Plumb RS, Siuzdak G. Cognitive analysis of metabolomics data for systems biology. Nature Protocols. PMID 33483720 DOI: 10.1038/s41596-020-00455-4  1
2020 Alvarez-Jarreta J, Rodrigues PRS, Fahy E, O'Connor A, Price A, Gaud C, Andrews S, Benton P, Siuzdak G, Hawksworth JI, Valdivia-Garcia M, Allen SM, O'Donnell VB. LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications. Bioinformatics (Oxford, England). PMID 33027502 DOI: 10.1093/bioinformatics/btaa856  0.01
2020 Guijas C, Montenegro-Burke JR, Cintron-Colon R, Domingo-Almenara X, Sanchez-Alavez M, Aguirre CA, Shankar K, Majumder EL, Billings E, Conti B, Siuzdak G. Metabolic adaptation to calorie restriction. Science Signaling. 13. PMID 32900879 DOI: 10.1126/Scisignal.Abb2490  1
2020 Xue J, Guijas C, Benton HP, Warth B, Siuzdak G. METLIN MS molecular standards database: a broad chemical and biological resource. Nature Methods. 17: 953-954. PMID 32839599 DOI: 10.1038/S41592-020-0942-5  1
2020 Xue J, Domingo-Almenara X, Guijas C, Palermo A, Rinschen MM, Isbell J, Benton HP, Siuzdak G. Enhanced in-Source Fragmentation Annotation Enables Novel Data Independent Acquisition and Autonomous METLIN Molecular Identification. Analytical Chemistry. 92: 6051-6059. PMID 32242660 DOI: 10.1021/Acs.Analchem.0C00409  1
2020 Montenegro-Burke JR, Guijas C, Siuzdak G. METLIN: A Tandem Mass Spectral Library of Standards. Methods in Molecular Biology (Clifton, N.J.). 2104: 149-163. PMID 31953817 DOI: 10.1007/978-1-0716-0239-3_9  1
2020 Domingo-Almenara X, Siuzdak G. Metabolomics Data Processing Using XCMS. Methods in Molecular Biology (Clifton, N.J.). 2104: 11-24. PMID 31953810 DOI: 10.1007/978-1-0716-0239-3_2  1
2019 Domingo-Almenara X, Guijas C, Billings E, Montenegro-Burke JR, Uritboonthai W, Aisporna AE, Chen E, Benton HP, Siuzdak G. The METLIN small molecule dataset for machine learning-based retention time prediction. Nature Communications. 10: 5811. PMID 31862874 DOI: 10.1038/S41467-019-13680-7  1
2019 Rinschen MM, Palygin O, Guijas C, Palermo A, Palacio-Escat N, Domingo-Almenara X, Montenegro-Burke R, Saez-Rodriguez J, Staruschenko A, Siuzdak G. Metabolic rewiring of the hypertensive kidney. Science Signaling. 12. PMID 31822592 DOI: 10.1126/Scisignal.Aax9760  1
2019 Cintron-Colon R, Johnson CW, Montenegro-Burke JR, Guijas C, Faulhaber L, Sanchez-Alavez M, Aguirre CA, Shankar K, Singh M, Galmozzi A, Siuzdak G, Saez E, Conti B. Activation of Kappa Opioid Receptor Regulates the Hypothermic Response to Calorie Restriction and Limits Body Weight Loss. Current Biology : Cb. PMID 31786059 DOI: 10.1016/J.Cub.2019.10.027  1
2019 Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, ... ... Siuzdak G, et al. PGRMC2 is an intracellular haem chaperone critical for adipocyte function. Nature. PMID 31748741 DOI: 10.1038/S41586-019-1774-2  1
2019 Riva A, Kuzyk O, Forsberg E, Siuzdak G, Pfann C, Herbold C, Daims H, Loy A, Warth B, Berry D. A fiber-deprived diet disturbs the fine-scale spatial architecture of the murine colon microbiome. Nature Communications. 10: 4366. PMID 31554820 DOI: 10.1038/S41467-019-12413-0  1
2019 Krantz GP, Lucas K, Wunderlich EL, Hoang LT, Avci R, Siuzdak G, Fields MW. Bulk phase resource ratio alters carbon steel corrosion rates and endogenously produced extracellular electron transfer mediators in a sulfate-reducing biofilm. Biofouling. 1-15. PMID 31402749 DOI: 10.1080/08927014.2019.1646731  1
2019 Rinschen MM, Ivanisevic J, Giera M, Siuzdak G. Identification of bioactive metabolites using activity metabolomics. Nature Reviews. Molecular Cell Biology. 20: 353-367. PMID 30814649 DOI: 10.1038/S41580-019-0108-4  1
2019 Domingo-Almenara X, Montenegro-Burke JR, Guijas C, Majumder EL, Benton HP, Siuzdak G. Autonomous METLIN-Guided In-source Fragment Annotation for Untargeted Metabolomics. Analytical Chemistry. 91: 3246-3253. PMID 30681830 DOI: 10.1021/Acs.Analchem.8B03126  1
2019 Warth B, Palermo A, Rattray NJW, Lee NV, Zhu Z, Hoang LT, Cai Y, Mazurek A, Dann S, VanArsdale T, Fantin VR, Shields D, Siuzdak G, Johnson CH. Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells. Metabolites. 9. PMID 30609717 DOI: 10.3390/Metabo9010007  1
2018 Guijas C, Siuzdak G. Reply to Comment on METLIN: A Technology Platform for Identifying Knowns and Unknowns. Analytical Chemistry. 90: 13128-13129. PMID 30299932 DOI: 10.1021/Acs.Analchem.8B04081  1
2018 Domingo-Almenara X, Montenegro-Burke JR, Ivanisevic J, Thomas A, Sidibé J, Teav T, Guijas C, Aisporna AE, Rinehart D, Hoang L, Nordström A, Gómez-Romero M, Whiley L, Lewis MR, Nicholson JK, ... ... Siuzdak G, et al. XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules. Nature Methods. PMID 30150755 DOI: 10.1038/S41592-018-0110-3  1
2018 Kok BP, Galmozzi A, Littlejohn NK, Albert V, Godio C, Kim W, Kim SM, Bland JS, Grayson N, Fang M, Meyerhof W, Siuzdak G, Srinivasan S, Behrens M, Saez E. Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits. Molecular Metabolism. PMID 30120064 DOI: 10.1016/J.Molmet.2018.07.013  1
2018 Montenegro-Burke JR, Woldstad CJ, Fang M, Bade AN, McMillan J, Edagwa B, Boska MD, Gendelman HE, Siuzdak G. Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress. Molecular Neurobiology. PMID 30069830 DOI: 10.1007/S12035-018-1273-8  1
2018 Palermo A, Forsberg EM, Warth B, Aisporna AE, Billings E, Kuang E, Benton HP, Berry D, Siuzdak G. Fluorinated Gold Nanoparticles for Nanostructure Imaging Mass Spectrometry. Acs Nano. PMID 29966083 DOI: 10.1021/Acsnano.8B02376  1
2018 Huan T, Palermo A, Ivanisevic J, Rinehart D, Edler D, Phommavongsay T, Benton HP, Guijas C, Domingo-Almenara X, Warth B, Siuzdak G. Autonomous Multimodal Metabolomics Data Integration for Comprehensive Pathway Analysis and Systems Biology. Analytical Chemistry. 90: 8396-8403. PMID 29893550 DOI: 10.1021/Acs.Analchem.8B00875  1
2018 Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, ... ... Siuzdak G, et al. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biology. 17: 259-273. PMID 29747066 DOI: 10.1016/J.Redox.2018.04.007  1
2018 Guijas C, Montenegro-Burke JR, Warth B, Spilker ME, Siuzdak G. Metabolomics activity screening for identifying metabolites that modulate phenotype. Nature Biotechnology. 36: 316-320. PMID 29621222 DOI: 10.1038/Nbt.4101  1
2018 Forsberg EM, Huan T, Rinehart D, Benton HP, Warth B, Hilmers B, Siuzdak G. Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online. Nature Protocols. 13: 633-651. PMID 29494574 DOI: 10.1038/Nprot.2017.151  1
2018 Giera M, Branco Dos Santos F, Siuzdak G. Metabolite-Induced Protein Expression Guided by Metabolomics and Systems Biology. Cell Metabolism. 27: 270-272. PMID 29414681 DOI: 10.1016/J.Cmet.2018.01.002  1
2018 Guijas C, Montenegro-Burke JR, Domingo-Almenara X, Palermo A, Warth B, Hermann G, Koellensperger G, Huan T, Uritboonthai W, Aisporna AE, Wolan DW, Spilker ME, Benton HP, Siuzdak G. METLIN: A Technology Platform for Identifying Knowns and Unknowns. Analytical Chemistry. PMID 29381867 DOI: 10.1021/Acs.Analchem.7B04424  1
2018 Warth B, Raffeiner P, Granados A, Huan T, Fang M, Forsberg EM, Benton HP, Goetz L, Johnson CH, Siuzdak G. Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy. Cell Chemical Biology. PMID 29337187 DOI: 10.1016/J.Chembiol.2017.12.010  1
2018 Domingo-Almenara X, Montenegro-Burke JR, Benton HP, Siuzdak G. Annotation: A Computational Solution for Streamlining Metabolomics Analysis. Analytical Chemistry. 90: 480-489. PMID 29039932 DOI: 10.1021/Acs.Analchem.7B03929  1
2017 Beyer BA, Fang M, Sadrian B, Montenegro-Burke JR, Plaisted WC, Kok BPC, Saez E, Kondo T, Siuzdak G, Lairson LL. Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation. Nature Chemical Biology. PMID 29131145 DOI: 10.1038/Nchembio.2517  1
2017 Johnson CH, Santidrian AF, LeBoeuf SE, Kurczy ME, Rattray NJW, Rattray Z, Warth B, Ritland M, Hoang LT, Loriot C, Higa J, Hansen JE, Felding BH, Siuzdak G. Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids. Cancer & Metabolism. 5: 9. PMID 29093815 DOI: 10.1186/S40170-017-0171-2  1
2017 Warth B, Spangler S, Fang M, Johnson CH, Forsberg EM, Granados A, Martin RL, Domingo-Almenara X, Huan T, Rinehart D, Montenegro-Burke JR, Hilmers B, Aisporna AE, Hoang LT, Uritboonthai W, ... ... Siuzdak G, et al. Exposome-Scale Investigations Guided by Global Metabolomics, Pathway Analysis, and Cognitive Computing. Analytical Chemistry. PMID 28945073 DOI: 10.1021/Acs.Analchem.7B02759  1
2017 Gendelman HE, Zhang Y, Santamaria P, Olson KE, Schutt CR, Bhatti D, Shetty BLD, Lu Y, Estes KA, Standaert DG, Heinrichs-Graham E, Larson L, Meza JL, Follett M, Forsberg E, ... Siuzdak G, et al. Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial. Npj Parkinson's Disease. 3: 10. PMID 28649610 DOI: 10.1038/S41531-017-0013-5  1
2017 Gao J, Louie KB, Steinke P, Bowen BP, Raad M, Zuckermann RN, Siuzdak G, Northen TR. Morphology Driven Control of Metabolite Selectivity using Nanostructure-initiator Mass Spectrometry. Analytical Chemistry. PMID 28520405 DOI: 10.1021/Acs.Analchem.7B00599  1
2017 Huan T, Forsberg EM, Rinehart D, Johnson CH, Ivanisevic J, Benton HP, Fang M, Aisporna A, Hilmers B, Poole FL, Thorgersen MP, Adams MWW, Krantz G, Fields MW, Robbins PD, ... ... Siuzdak G, et al. Systems biology guided by XCMS Online metabolomics. Nature Methods. 14: 461-462. PMID 28448069 DOI: 10.1038/Nmeth.4260  1
2017 Warth B, Levin N, Rinehart D, Teijaro J, Benton HP, Siuzdak G. Metabolizing Data in the Cloud. Trends in Biotechnology. PMID 28117091 DOI: 10.1016/J.Tibtech.2016.12.010  1
2016 Montenegro-Burke JR, Aisporna AE, Benton HP, Rinehart D, Fang M, Huan T, Warth B, Forsberg EM, Abe BT, Ivanisevic J, Teyton L, Lairson LL, Siuzdak G. Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes. Analytical Chemistry. PMID 27983788 DOI: 10.1021/Acs.Analchem.6B03890  1
2016 Johnson CH, Spilker ME, Goetz L, Peterson SN, Siuzdak G. Metabolite and Microbiome Interplay in Cancer Immunotherapy. Cancer Research. PMID 27729325 DOI: 10.1158/0008-5472.Can-16-0309  1
2016 Wang J, Westenskow PD, Fang M, Friedlander M, Siuzdak G. Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 374. PMID 27644974 DOI: 10.1098/Rsta.2015.0376  1
2016 Montenegro Burke JR, Phommavongsay T, Aisporna AE, Huan T, Rinehart D, Forsberg EM, Poole FL, Thorgersen MP, Adams MW, Krantz G, Fields MW, Robbins PD, Niedernhofer LJ, Lairson LL, Benton HP, ... Siuzdak G, et al. Smartphone Analytics: Expanding the Lab into the Cloud. Analytical Chemistry. PMID 27560777 DOI: 10.1021/Acs.Analchem.6B02676  1
2016 Forsberg E, Fang M, Siuzdak G. Staying Alive: Measuring Intact Viable Microbes with Electrospray Ionization Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 27456857 DOI: 10.1007/S13361-016-1440-Y  1
2016 Ivanisevic J, Stauch KL, Petrascheck M, Benton HP, Epstein AA, Fang M, Gorantla S, Tran M, Hoang L, Kurczy ME, Boska MD, Gendelman HE, Fox HS, Siuzdak G. Metabolic drift in the aging brain. Aging. PMID 27182841 DOI: 10.18632/aging.100961  1
2016 Kurczy ME, Forsberg EM, Thorgersen MP, Poole FL, Benton HP, Ivanisevic J, Tran ML, Wall JD, Elias DA, Adams MW, Siuzdak G. Global Isotope Metabolomics Reveals Adaptive Strategies for Nitrogen Assimilation in Pseudomonas. Acs Chemical Biology. PMID 27045776 DOI: 10.1021/Acschembio.6B00082  1
2016 Johnson CH, Ivanisevic J, Siuzdak G. Metabolomics: beyond biomarkers and towards mechanisms. Nature Reviews. Molecular Cell Biology. PMID 26979502 DOI: 10.1038/Nrm.2016.25  1
2016 Kurihara T, Westenskow PD, Gantner ML, Usui Y, Schultz A, Bravo S, Aguilar E, Wittgrove C, Friedlander MS, Paris LP, Chew E, Siuzdak G, Friedlander M. Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration. Elife. 5. PMID 26978795 DOI: 10.7554/Elife.14319  1
2016 Paris LP, Johnson CH, Aguilar E, Usui Y, Cho K, Hoang LT, Feitelberg D, Benton HP, Westenskow PD, Kurihara T, Trombley J, Tsubota K, Ueda S, Wakabayashi Y, Patti GJ, ... ... Siuzdak G, et al. Global metabolomics reveals metabolic dysregulation in ischemic retinopathy. Metabolomics : Official Journal of the Metabolomic Society. 12: 15. PMID 26617478 DOI: 10.1007/S11306-015-0877-5  1
2016 Kurihara T, Westenskow PD, Gantner ML, Usui Y, Schultz A, Bravo S, Aguilar E, Wittgrove C, Friedlander MS, Paris LP, Chew E, Siuzdak G, Friedlander M. Author response: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration Elife. DOI: 10.7554/Elife.14319.030  1
2015 Fang M, Ivanisevic J, Benton HP, Johnson CH, Patti GJ, Hoang LT, Uritboonthai W, Kurczy ME, Siuzdak G. Thermal Degradation of Small Molecules: A Global Metabolomic Investigation. Analytical Chemistry. PMID 26434689 DOI: 10.1021/Acs.Analchem.5B03003  1
2015 Kurczy ME, Ivanisevic J, Johnson CH, Uritboonthai W, Hoang L, Fang M, Hicks M, Aldebot A, Rinehart D, Mellander LJ, Tautenhahn R, Patti GJ, Spilker ME, Benton HP, Siuzdak G. Determining Conserved Metabolic Biomarkers from a Million Database Queries. Bioinformatics (Oxford, England). PMID 26275895 DOI: 10.1093/Bioinformatics/Btv475  1
2015 Ivanisevic J, Elias D, Deguchi H, Averell PM, Kurczy M, Johnson CH, Tautenhahn R, Zhu Z, Watrous J, Jain M, Griffin J, Patti GJ, Siuzdak G. Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis. Scientific Reports. 5: 12757. PMID 26244428 DOI: 10.1038/Srep12757  1
2015 Johnson CH, Patti GJ, Courade JP, Shriver LP, Hoang LT, Manchester M, Siuzdak G. Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 396-401. PMID 26232265 DOI: 10.1007/S11481-015-9624-Y  1
2015 Ivanisevic J, Siuzdak G. The Role of Metabolomics in Brain Metabolism Research. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 391-5. PMID 26201839 DOI: 10.1007/S11481-015-9621-1  1
2015 Benton PH, Ivanisevic J, Rinehart D, Epstein A, Kurczy ME, Boska MD, Gendelman HE, Siuzdak G. An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data. Metabolomics : Official Journal of the Metabolomic Society. 11: 1029-1034. PMID 26195918 DOI: 10.1007/S11306-014-0759-2  1
2015 Deguchi H, Banerjee Y, Trauger S, Siuzdak G, Kalisiak E, Fernández JA, Hoang L, Tran M, Yegneswaran S, Elias DJ, Griffin JH. Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data. Blood. 126: 1595-600. PMID 26175037 DOI: 10.1182/Blood-2015-03-636761  1
2015 Johnson CH, Dejea CM, Edler D, Hoang LT, Santidrian AF, Felding BH, Ivanisevic J, Cho K, Wick EC, Hechenbleikner EM, Uritboonthai W, Goetz L, Casero RA, Pardoll DM, White JR, ... ... Siuzdak G, et al. Metabolism links bacterial biofilms and colon carcinogenesis. Cell Metabolism. 21: 891-7. PMID 25959674 DOI: 10.1016/J.Cmet.2015.04.011  1
2015 Nikolskiy I, Siuzdak G, Patti GJ. Discriminating precursors of common fragments for large-scale metabolite profiling by triple quadrupole mass spectrometry. Bioinformatics (Oxford, England). 31: 2017-23. PMID 25691443 DOI: 10.1093/Bioinformatics/Btv085  1
2015 Kurczy ME, Zhu ZJ, Ivanisevic J, Schuyler AM, Lalwani K, Santidrian AF, David JM, Giddabasappa A, Roberts AJ, Olivos HJ, O'Brien PJ, Franco L, Fields MW, Paris LP, Friedlander M, ... ... Siuzdak G, et al. Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids. Nature Communications. 6: 5998. PMID 25601659 DOI: 10.1038/Ncomms6998  1
2015 Benton HP, Ivanisevic J, Mahieu NG, Kurczy ME, Johnson CH, Franco L, Rinehart D, Valentine E, Gowda H, Ubhi BK, Tautenhahn R, Gieschen A, Fields MW, Patti GJ, Siuzdak G. Autonomous metabolomics for rapid metabolite identification in global profiling. Analytical Chemistry. 87: 884-91. PMID 25496351 DOI: 10.1021/Ac5025649  1
2015 Johnson CH, Ivanisevic J, Benton HP, Siuzdak G. Bioinformatics: the next frontier of metabolomics. Analytical Chemistry. 87: 147-56. PMID 25389922 DOI: 10.1021/Ac5040693  1
2015 Kurczy ME, Northen TR, Trauger SA, Siuzdak G. Nanostructure imaging mass spectrometry: the role of fluorocarbons in metabolite analysis and yoctomole level sensitivity. Methods in Molecular Biology (Clifton, N.J.). 1203: 141-9. PMID 25361674 DOI: 10.1007/978-1-4939-1357-2_14  1
2014 Patti GJ, Tautenhahn R, Johannsen D, Kalisiak E, Ravussin E, Brüning JC, Dillin A, Siuzdak G. Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension. Metabolomics : Official Journal of the Metabolomic Society. 10: 737-743. PMID 25530742 DOI: 10.1007/S11306-013-0608-8  1
2014 Ivanisevic J, Epstein AA, Kurczy ME, Benton PH, Uritboonthai W, Fox HS, Boska MD, Gendelman HE, Siuzdak G. Brain region mapping using global metabolomics. Chemistry & Biology. 21: 1575-84. PMID 25457182 DOI: 10.1016/J.Chembiol.2014.09.016  1
2014 Cho K, Mahieu N, Ivanisevic J, Uritboonthai W, Chen YJ, Siuzdak G, Patti GJ. isoMETLIN: a database for isotope-based metabolomics. Analytical Chemistry. 86: 9358-61. PMID 25166490 DOI: 10.1021/Ac5029177  1
2014 Gowda H, Ivanisevic J, Johnson CH, Kurczy ME, Benton HP, Rinehart D, Nguyen T, Ray J, Kuehl J, Arevalo B, Westenskow PD, Wang J, Arkin AP, Deutschbauer AM, Patti GJ, ... Siuzdak G, et al. Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses. Analytical Chemistry. 86: 6931-9. PMID 24934772 DOI: 10.1021/Ac500734C  1
2014 Rinehart D, Johnson CH, Nguyen T, Ivanisevic J, Benton HP, Lloyd J, Arkin AP, Deutschbauer AM, Patti GJ, Siuzdak G. Metabolomic data streaming for biology-dependent data acquisition. Nature Biotechnology. 32: 524-7. PMID 24911492 DOI: 10.1038/Nbt.2927  1
2014 Johnson CH, Fisher TS, Hoang LT, Felding BH, Siuzdak G, O'Brien PJ. Luciferase does not Alter Metabolism in Cancer Cells. Metabolomics : Official Journal of the Metabolomic Society. 10: 354-360. PMID 24791164 DOI: 10.1007/S11306-014-0622-5  1
2014 Deguchi H, Elias DJ, Trauger S, Zhang HM, Kalisiak E, Siuzdak G, Griffin JH. Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids. British Journal of Haematology. 165: 409-12. PMID 24450944 DOI: 10.1111/Bjh.12720  1
2013 O'Brien PJ, Lee M, Spilker ME, Zhang CC, Yan Z, Nichols TC, Li W, Johnson CH, Patti GJ, Siuzdak G. Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging. Cancer & Metabolism. 1: 4. PMID 24280026 DOI: 10.1186/2049-3002-1-4  1
2013 Ivanisevic J, Zhu ZJ, Plate L, Tautenhahn R, Chen S, O'Brien PJ, Johnson CH, Marletta MA, Patti GJ, Siuzdak G. Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. Analytical Chemistry. 85: 6876-84. PMID 23781873 DOI: 10.1021/Ac401140H  1
2013 Zhu ZJ, Schultz AW, Wang J, Johnson CH, Yannone SM, Patti GJ, Siuzdak G. Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database. Nature Protocols. 8: 451-60. PMID 23391889 DOI: 10.1038/Nprot.2013.004  1
2013 Blankman JL, Long JZ, Trauger SA, Siuzdak G, Cravatt BF. ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proceedings of the National Academy of Sciences of the United States of America. 110: 1500-5. PMID 23297193 DOI: 10.1073/Pnas.1217121110  1
2013 Patti GJ, Tautenhahn R, Rinehart D, Cho K, Shriver LP, Manchester M, Nikolskiy I, Johnson CH, Mahieu NG, Siuzdak G. A view from above: cloud plots to visualize global metabolomic data. Analytical Chemistry. 85: 798-804. PMID 23206250 DOI: 10.1021/Ac3029745  1
2013 Siuzdak G. Abstract ED04-02: XCMS cloud-based metabolomics: A platform for the cancer biologist Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Ed04-02  0.01
2012 Tautenhahn R, Cho K, Uritboonthai W, Zhu Z, Patti GJ, Siuzdak G. An accelerated workflow for untargeted metabolomics using the METLIN database. Nature Biotechnology. 30: 826-8. PMID 22965049 DOI: 10.1038/Nbt.2348  1
2012 Tautenhahn R, Patti GJ, Rinehart D, Siuzdak G. XCMS Online: a web-based platform to process untargeted metabolomic data. Analytical Chemistry. 84: 5035-9. PMID 22533540 DOI: 10.1021/Ac300698C  1
2012 Krohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Translational Medicine. 1: 96-109. PMID 22532929 DOI: 10.5966/Sctm.2011-0057  1
2012 Patti GJ, Yanes O, Siuzdak G. Innovation: Metabolomics: the apogee of the omics trilogy. Nature Reviews. Molecular Cell Biology. 13: 263-9. PMID 22436749 DOI: 10.1038/Nrm3314  1
2012 Greving M, Cheng X, Reindl W, Bowen B, Deng K, Louie K, Nyman M, Cohen J, Singh A, Simmons B, Adams P, Siuzdak G, Northen T. Acoustic deposition with NIMS as a high-throughput enzyme activity assay. Analytical and Bioanalytical Chemistry. 403: 707-11. PMID 22407334 DOI: 10.1007/S00216-012-5908-8  1
2012 Patti GJ, Tautenhahn R, Siuzdak G. Meta-analysis of untargeted metabolomic data from multiple profiling experiments. Nature Protocols. 7: 508-16. PMID 22343432 DOI: 10.1038/Nprot.2011.454  1
2012 Patti GJ, Yanes O, Shriver LP, Courade JP, Tautenhahn R, Manchester M, Siuzdak G. Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin. Nature Chemical Biology. 8: 232-4. PMID 22267119 DOI: 10.1038/Nchembio.767  1
2012 Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G, Izpisua Belmonte JC. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Research. 22: 168-77. PMID 22064701 DOI: 10.1038/Cr.2011.177  1
2011 Marchetti V, Yanes O, Aguilar E, Wang M, Friedlander D, Moreno S, Storm K, Zhan M, Naccache S, Nemerow G, Siuzdak G, Friedlander M. Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. Scientific Reports. 1: 76. PMID 22355595 DOI: 10.1038/Srep00076  1
2011 Long JZ, Cisar JS, Milliken D, Niessen S, Wang C, Trauger SA, Siuzdak G, Cravatt BF. Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids. Nature Chemical Biology. 7: 763-5. PMID 21926997 DOI: 10.1038/Nchembio.659  1
2011 Lancaster WA, Praissman JL, Poole FL, Cvetkovic A, Menon AL, Scott JW, Jenney FE, Thorgersen MP, Kalisiak E, Apon JV, Trauger SA, Siuzdak G, Tainer JA, Adams MW. A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data. Bmc Bioinformatics. 12: 64. PMID 21356119 DOI: 10.1186/1471-2105-12-64  1
2011 Yanes O, Tautenhahn R, Patti GJ, Siuzdak G. Expanding coverage of the metabolome for global metabolite profiling. Analytical Chemistry. 83: 2152-61. PMID 21329365 DOI: 10.1021/Ac102981K  1
2011 Tautenhahn R, Patti GJ, Kalisiak E, Miyamoto T, Schmidt M, Lo FY, McBee J, Baliga NS, Siuzdak G. metaXCMS: second-order analysis of untargeted metabolomics data. Analytical Chemistry. 83: 696-700. PMID 21174458 DOI: 10.1021/Ac102980G  1
2011 Powers ME, Smith PA, Roberts TC, Fowler BJ, King CC, Trauger SA, Siuzdak G, Romesberg FE. Type I signal peptidase and protein secretion in Staphylococcus epidermidis. Journal of Bacteriology. 193: 340-8. PMID 21075926 DOI: 10.1128/Jb.01052-10  1
2011 Greving MP, Patti GJ, Siuzdak G. Nanostructure-initiator mass spectrometry metabolite analysis and imaging. Analytical Chemistry. 83: 2-7. PMID 21049956 DOI: 10.1021/Ac101565F  1
2011 Pendyala G, Trauger SA, Siuzdak G, Fox HS. Short communication: quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity. Aids Research and Human Retroviruses. 27: 179-82. PMID 20929344 DOI: 10.1089/Aid.2010.0090  1
2011 Patti GJ, Tautenhahn R, Fonslow BR, Cho Y, Deutschbauer A, Arkin A, Northen T, Siuzdak G. Meta-analysis of global metabolomics and proteomics data to link alterations with phenotype Spectroscopy. 26: 151-154. DOI: 10.3233/Spe-2011-0534  1
2011 Deguchi H, Trauger S, Kalisiak E, Zhang H, Siuzdak G, Griffin JH, Elias DJ. Warfarin Untargeted Metabolomics Study Identifies Novel Procoagulant Ethanolamide Lipids Blood. 118: 1200-1200. DOI: 10.1182/Blood.V118.21.1200.1200  1
2011 Greving MP, Zhang C, Yan Z, Spilker ME, Li W, Siuzdak G, O'Brien PJ. Abstract LB-333: Metabolic imaging of cancer using nanostructure-initiator mass spectrometry Cellular and Molecular Biology. 71. DOI: 10.1158/1538-7445.Am2011-Lb-333  1
2010 Kopp F, Komatsu T, Nomura DK, Trauger SA, Thomas JR, Siuzdak G, Simon GM, Cravatt BF. The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice. Chemistry & Biology. 17: 831-40. PMID 20797612 DOI: 10.1016/J.Chembiol.2010.06.009  1
2010 Patti GJ, Shriver LP, Wassif CA, Woo HK, Uritboonthai W, Apon J, Manchester M, Porter FD, Siuzdak G. Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome. Neuroscience. 170: 858-64. PMID 20670678 DOI: 10.1016/J.Neuroscience.2010.07.038  1
2010 Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL, Jenney FE, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ, Trauger SA, Kalisiak E, Apon JV, Siuzdak G, Yannone SM, et al. Microbial metalloproteomes are largely uncharacterized. Nature. 466: 779-82. PMID 20639861 DOI: 10.1038/Nature09265  1
2010 Facciotti MT, Pang WL, Lo FY, Whitehead K, Koide T, Masumura K, Pan M, Kaur A, Larsen DJ, Reiss DJ, Hoang L, Kalisiak E, Northen T, Trauger SA, Siuzdak G, et al. Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. Bmc Systems Biology. 4: 64. PMID 20470417 DOI: 10.1186/1752-0509-4-64  1
2010 Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G. Metabolic oxidation regulates embryonic stem cell differentiation. Nature Chemical Biology. 6: 411-7. PMID 20436487 DOI: 10.1038/Nchembio.364  1
2010 Lowe RD, Szili EJ, Kirkbride P, Thissen H, Siuzdak G, Voelcker NH. Combined immunocapture and laser desorption/ionization mass spectrometry on porous silicon. Analytical Chemistry. 82: 4201-8. PMID 20411919 DOI: 10.1021/Ac100455X  0.01
2010 Patti GJ, Woo HK, Yanes O, Shriver L, Thomas D, Uritboonthai W, Apon JV, Steenwyk R, Manchester M, Siuzdak G. Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging. Analytical Chemistry. 82: 121-8. PMID 19961200 DOI: 10.1021/Ac9014353  1
2010 Pendyala G, Trauger SA, Siuzdak G, Fox HS. Quantitative plasma proteomic profiling identifies the vitamin E binding protein afamin as a potential pathogenic factor in SIV induced CNS disease. Journal of Proteome Research. 9: 352-8. PMID 19908921 DOI: 10.1021/Pr900685U  1
2010 Dorrell MI, Aguilar E, Jacobson R, Trauger SA, Friedlander J, Siuzdak G, Friedlander M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. Glia. 58: 43-54. PMID 19544395 DOI: 10.1002/Glia.20900  1
2009 Crews B, Wikoff WR, Patti GJ, Woo HK, Kalisiak E, Heideker J, Siuzdak G. Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data. Analytical Chemistry. 81: 8538-44. PMID 19764780 DOI: 10.1021/Ac9014947  1
2009 Wikoff WR, Kalisak E, Trauger S, Manchester M, Siuzdak G. Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. Journal of Proteome Research. 8: 3578-87. PMID 19496611 DOI: 10.1021/Pr900275P  1
2009 Woo HK, Go EP, Hoang L, Trauger SA, Bowen B, Siuzdak G, Northen TR. Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 23: 1849-55. PMID 19449318 DOI: 10.1002/Rcm.4076  1
2009 Koudelka KJ, Destito G, Plummer EM, Trauger SA, Siuzdak G, Manchester M. Endothelial targeting of cowpea mosaic virus (CPMV) via surface vimentin Plos Pathogens. 5. PMID 19412526 DOI: 10.1371/Journal.Ppat.1000417  1
2009 Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell. 4: 381-4. PMID 19398399 DOI: 10.1016/J.Stem.2009.04.005  1
2009 Yanes O, Woo HK, Northen TR, Oppenheimer SR, Shriver L, Apon J, Estrada MN, Potchoiba MJ, Steenwyk R, Manchester M, Siuzdak G. Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis. Analytical Chemistry. 81: 2969-75. PMID 19301920 DOI: 10.1021/Ac802576Q  1
2009 Pendyala G, Trauger SA, Kalisiak E, Ellis RJ, Siuzdak G, Fox HS. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys. Journal of Proteome Research. 8: 2253-60. PMID 19281240 DOI: 10.1021/Pr800854T  1
2009 Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC, Siuzdak G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America. 106: 3698-703. PMID 19234110 DOI: 10.1073/Pnas.0812874106  1
2009 Dorrell MI, Aguilar E, Jacobson R, Yanes O, Gariano R, Heckenlively J, Banin E, Ramirez GA, Gasmi M, Bird A, Siuzdak G, Friedlander M. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. The Journal of Clinical Investigation. 119: 611-23. PMID 19188685 DOI: 10.1172/Jci35977  1
2009 Kalisiak J, Trauger SA, Kalisiak E, Morita H, Fokin VV, Adams MW, Sharpless KB, Siuzdak G. Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach. Journal of the American Chemical Society. 131: 378-86. PMID 19055353 DOI: 10.1021/Ja808172N  1
2009 Menon AL, Poole FL, Cvetkovic A, Trauger SA, Kalisiak E, Scott JW, Shanmukh S, Praissman J, Jenney FE, Wikoff WR, Apon JV, Siuzdak G, Adams MW. Novel multiprotein complexes identified in the hyperthermophilic archaeon Pyrococcus furiosus by non-denaturing fractionation of the native proteome. Molecular & Cellular Proteomics : McP. 8: 735-51. PMID 19043064 DOI: 10.1074/Mcp.M800246-Mcp200  1
2008 Bunner AE, Trauger SA, Siuzdak G, Williamson JR. Quantitative ESI-TOF analysis of macromolecular assembly kinetics. Analytical Chemistry. 80: 9379-86. PMID 19007188 DOI: 10.1021/Ac8020505  1
2008 Woo HK, Northen TR, Yanes O, Siuzdak G. Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis. Nature Protocols. 3: 1341-9. PMID 18714302 DOI: 10.1038/Nprot.2008.110  1
2008 Benton HP, Wong DM, Trauger SA, Siuzdak G. XCMS2: processing tandem mass spectrometry data for metabolite identification and structural characterization. Analytical Chemistry. 80: 6382-9. PMID 18627180 DOI: 10.1021/Ac800795F  1
2008 Wikoff WR, Pendyala G, Siuzdak G, Fox HS. Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. The Journal of Clinical Investigation. 118: 2661-9. PMID 18521184 DOI: 10.1172/Jci34138  1
2008 Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. Journal of the American Society of Nephrology : Jasn. 19: 1732-40. PMID 18508962 DOI: 10.1681/Asn.2008020180  1
2008 Northen TR, Lee JC, Hoang L, Raymond J, Hwang DR, Yannone SM, Wong CH, Siuzdak G. A nanostructure-initiator mass spectrometry-based enzyme activity assay. Proceedings of the National Academy of Sciences of the United States of America. 105: 3678-83. PMID 18319341 DOI: 10.1073/Pnas.0712332105  1
2008 Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiological Genomics. 33: 180-92. PMID 18270321 DOI: 10.1152/Physiolgenomics.00207.2007  1
2008 Trauger SA, Kalisak E, Kalisiak J, Morita H, Weinberg MV, Menon AL, Poole FL, Adams MW, Siuzdak G. Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile. Journal of Proteome Research. 7: 1027-35. PMID 18247545 DOI: 10.1021/Pr700609J  1
2008 Nordström A, Want E, Northen T, Lehtiö J, Siuzdak G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Analytical Chemistry. 80: 421-9. PMID 18085752 DOI: 10.1021/Ac701982E  1
2008 O'Maille G, Go EP, Hoang L, Want EJ, Smith C, O'Maille P, Nordström A, Morita H, Qin C, Uritboonthai W, Apon J, Moore R, Garrett J, Siuzdak G. Metabolomics relative quantitation with mass spectrometry using chemical derivatization and isotope labeling Spectroscopy. 22: 327-343. DOI: 10.3233/Spe-2008-0361  1
2007 Pendyala G, Want EJ, Webb W, Siuzdak G, Fox HS. Biomarkers for neuroAIDS: the widening scope of metabolomics. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 72-80. PMID 18040828 DOI: 10.1007/S11481-006-9041-3  1
2007 Northen TR, Yanes O, Northen MT, Marrinucci D, Uritboonthai W, Apon J, Golledge SL, Nordström A, Siuzdak G. Clathrate nanostructures for mass spectrometry. Nature. 449: 1033-6. PMID 17960240 DOI: 10.1038/Nature06195  1
2007 Wikoff WR, Gangoiti JA, Barshop BA, Siuzdak G. Metabolomics identifies perturbations in human disorders of propionate metabolism. Clinical Chemistry. 53: 2169-76. PMID 17951291 DOI: 10.1373/Clinchem.2007.089011  1
2007 Northen TR, Woo HK, Northen MT, Nordström A, Uritboonthail W, Turner KL, Siuzdak G. High surface area of porous silicon drives desorption of intact molecules. Journal of the American Society For Mass Spectrometry. 18: 1945-9. PMID 17881245 DOI: 10.1016/J.Jasms.2007.08.009  1
2007 Lissauer ME, Johnson SB, Siuzdak G, Bochicchio G, Whiteford C, Nussbaumer B, Moore R, Scalea TM. Coagulation and complement protein differences between septic and uninfected systemic inflammatory response syndrome patients. The Journal of Trauma. 62: 1082-92; discussion . PMID 17495706 DOI: 10.1097/Ta.0B013E31804D23E1  0.01
2007 Mutch DM, O'Maille G, Wikoff WR, Wiedmer T, Sims PJ, Siuzdak G. Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice. Genome Biology. 8: R38. PMID 17355638 DOI: 10.1186/Gb-2007-8-3-R38  1
2007 Go EP, Uritboonthai W, Apon JV, Trauger SA, Nordstrom A, O'Maille G, Brittain SM, Peters EC, Siuzdak G. Selective metabolite and peptide capture/mass detection using fluorous affinity tags. Journal of Proteome Research. 6: 1492-9. PMID 17343404 DOI: 10.1021/Pr060608S  1
2006 Steenwyk RC, Hutzler JM, Sams J, Shen Z, Siuzdak G. Atmospheric pressure desorption/ionization on silicon ion trap mass spectrometry applied to the quantitation of midazolam in rat plasma and determination of midazolam 1'-hydroxylation kinetics in human liver microsomes. Rapid Communications in Mass Spectrometry : Rcm. 20: 3717-22. PMID 17117443 DOI: 10.1002/Rcm.2796  1
2006 Go EP, Wikoff WR, Shen Z, O'Maille G, Morita H, Conrads TP, Nordstrom A, Trauger SA, Uritboonthai W, Lucas DA, Chan KC, Veenstra TD, Lewicki H, Oldstone MB, Schneemann A, ... Siuzdak G, et al. Mass spectrometry reveals specific and global molecular transformations during viral infection. Journal of Proteome Research. 5: 2405-16. PMID 16944953 DOI: 10.1021/Pr060215T  1
2006 Lee J, Wu C, Apon JV, Siuzdak G, Wong C. Reactivity-based one-pot synthesis of the tumor-associated antigen N3 minor octasaccharide for the development of a photocleavable DIOS-MS sugar array. Angewandte Chemie. 45: 2753-2757. PMID 16548041 DOI: 10.1002/Anie.200504067  1
2006 Smith CA, Want EJ, O'Maille G, Abagyan R, Siuzdak G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Analytical Chemistry. 78: 779-87. PMID 16448051 DOI: 10.1021/Ac051437Y  1
2006 Want EJ, O'Maille G, Smith CA, Brandon TR, Uritboonthai W, Qin C, Trauger SA, Siuzdak G. Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Analytical Chemistry. 78: 743-52. PMID 16448047 DOI: 10.1021/Ac051312T  1
2005 Smith CA, O'Maille G, Want EJ, Qin C, Trauger SA, Brandon TR, Custodio DE, Abagyan R, Siuzdak G. METLIN: a metabolite mass spectral database. Therapeutic Drug Monitoring. 27: 747-51. PMID 16404815 DOI: 10.1097/01.Ftd.0000179845.53213.39  1
2005 Luo G, Chen Y, Siuzdak G, Vertes A. Surface modification and laser pulse length effects on internal energy transfer in DIOS. The Journal of Physical Chemistry. B. 109: 24450-6. PMID 16375447 DOI: 10.1021/Jp054311D  1
2005 Talkington MW, Siuzdak G, Williamson JR. An assembly landscape for the 30S ribosomal subunit. Nature. 438: 628-32. PMID 16319883 DOI: 10.1038/Nature04261  1
2005 Want EJ, Cravatt BF, Siuzdak G. The expanding role of mass spectrometry in metabolite profiling and characterization. Chembiochem : a European Journal of Chemical Biology. 6: 1941-51. PMID 16206229 DOI: 10.1002/Cbic.200500151  1
2005 Lacy ER, Wang Y, Post J, Nourse A, Webb W, Mapelli M, Musacchio A, Siuzdak G, Kriwacki RW. Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division. Journal of Molecular Biology. 349: 764-73. PMID 15890360 DOI: 10.1016/J.Jmb.2005.04.019  1
2005 Go EP, Apon JV, Luo G, Saghatelian A, Daniels RH, Sahi V, Dubrow R, Cravatt BF, Vertes A, Siuzdak G. Desorption/ionization on silicon nanowires. Analytical Chemistry. 77: 1641-6. PMID 15762567 DOI: 10.1021/Ac048460O  1
2005 Bothner B, Taylor D, Jun B, Lee KK, Siuzdak G, Schultz CP, Schlutz CP, Johnson JE. Maturation of a tetravirus capsid alters the dynamic properties and creates a metastable complex. Virology. 334: 17-27. PMID 15749119 DOI: 10.1016/J.Virol.2005.01.017  1
2004 Saghatelian A, Trauger SA, Want EJ, Hawkins EG, Siuzdak G, Cravatt BF. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry. 43: 14332-9. PMID 15533037 DOI: 10.1021/Bi0480335  1
2004 Meng JC, Siuzdak G, Finn MG. Affinity mass spectrometry from a tailored porous silicon surface. Chemical Communications (Cambridge, England). 2108-9. PMID 15367998 DOI: 10.1039/B408200A  1
2004 Trauger SA, Wu E, Bark SJ, Nemerow GR, Siuzdak G. The identification of an adenovirus receptor by using affinity capture and mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 5: 1095-9. PMID 15300833 DOI: 10.1002/Cbic.200400037  1
2004 Trauger SA, Go EP, Shen Z, Apon JV, Compton BJ, Bouvier ES, Finn MG, Siuzdak G. High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon. Analytical Chemistry. 76: 4484-9. PMID 15283591 DOI: 10.1021/Ac049657J  1
2004 Shen Z, Go EP, Gamez A, Apon JV, Fokin V, Greig M, Ventura M, Crowell JE, Blixt O, Paulson JC, Stevens RC, Finn MG, Siuzdak G. A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform. Chembiochem : a European Journal of Chemical Biology. 5: 921-7. PMID 15239048 DOI: 10.1002/Cbic.200400008  1
2004 Wu E, Trauger SA, Pache L, Mullen TM, von Seggern DJ, Siuzdak G, Nemerow GR. Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis. Journal of Virology. 78: 3897-905. PMID 15047806 DOI: 10.1128/Jvi.78.8.3897-3905.2004  1
2004 Bothner B, Siuzdak G. Electrospray ionization of a whole virus: analyzing mass, structure, and viability. Chembiochem : a European Journal of Chemical Biology. 5: 258-60. PMID 14997515 DOI: 10.1002/Cbic.200300754  1
2004 Meng J, Averbuj C, Lewis WG, Siuzdak G, Finn MG. Cleavable Linkers for Porous Silicon‐Based Mass Spectrometry Angewandte Chemie. 43: 1255-1260. PMID 14991792 DOI: 10.1002/Anie.200352803  1
2004 Kriwacki R, Reisdorph N, Siuzdak G. Protein structure characterization with mass spectrometry Spectroscopy. 18: 37-47. DOI: 10.1155/2004/407960  1
2004 Thomas JJ, Bothner B, Traina J, Benner WH, Siuzdak G. Electrospray ion mobility spectrometry of intact viruses Spectroscopy. 18: 31-36. DOI: 10.1155/2004/376572  1
2003 Go EP, Shen Z, Harris K, Siuzdak G. Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition. Analytical Chemistry. 75: 5475-9. PMID 14710827 DOI: 10.1021/Ac034376H  1
2003 Reisdorph N, Thomas JJ, Katpally U, Chase E, Harris K, Siuzdak G, Smith TJ. Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology. 314: 34-44. PMID 14517058 DOI: 10.1016/S0042-6822(03)00452-5  1
2003 Go EP, Prenni JE, Wei J, Jones A, Hall SC, Witkowska HE, Shen Z, Siuzdak G. Desorption/ionization on silicon time-of-flight/time-of-flight mass spectrometry. Analytical Chemistry. 75: 2504-6. PMID 12918997 DOI: 10.1021/Ac026253N  1
2003 Yao S, Meng J, Siuzdak G, Finn MG. New catalysts for the asymmetric hydrosilylation of ketones discovered by mass spectrometry screening. Journal of Organic Chemistry. 68: 2540-2546. PMID 12662022 DOI: 10.1021/Jo026365E  1
2003 Prenni JE, Shen Z, Trauger S, Chen W, Siuzdak G. Protein characterization using Liquid Chromatography Desorption Ionization on Silicon Mass Spectrometry (LC-DIOS-MS) Spectroscopy. 17: 693-698. DOI: 10.1155/2003/172838  1
2003 Lewis WG, Shen Z, Finn MG, Siuzdak G. Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications International Journal of Mass Spectrometry. 226: 107-116. DOI: 10.1016/S1387-3806(02)00973-9  1
2002 Smith TJ, Schmidt T, Fang J, Wu J, Siuzdak G, Stanley CA. The structure of apo human glutamate dehydrogenase details subunit communication and allostery Journal of Molecular Biology. 318: 765-777. PMID 12054821 DOI: 10.1016/S0022-2836(02)00161-4  1
2002 Bothner B, Carmitchel L, Staniszewski K, Sonderegger M, Siuzdak G. Biomolecule structure characterization in the gas phase using mass spectrometry Spectroscopy. 16: 71-79. DOI: 10.1155/2002/243284  1
2001 Fuerstenau SD, Benner WH, Thomas JJ, Brugidou C, Bothner B, Siuzdak G. Mass Spectrometry of an Intact Virus. Angewandte Chemie (International Ed. in English). 40: 541-544. PMID 29712014 DOI: 10.1002/1521-3773(20010202)40:3<541::Aid-Anie541>3.0.Co;2-K  1
2001 Thomas JJ, Shen Z, Crowell JE, Finn MG, Siuzdak G. Desorption/ionization on silicon (DIOS): a diverse mass spectrometry platform for protein characterization. Proceedings of the National Academy of Sciences of the United States of America. 98: 4932-7. PMID 11296246 DOI: 10.1073/Pnas.081069298  1
2001 Fuerstenau SD, Benner WH, Thomas JJ, Brugidou C, Bothner B, Siuzdak G. Mass Spectrometry of an Intact Virus The authors gratefully acknowledge Jennifer Boydston for her helpful comments and suggestions. G.S. is grateful for support from the NIH (GM55775). The work at LBL was supported by the Director, Office of Energy Research, Office of Health and Environmental Research, Human Genome Program, U.S. Department of Energy under contract number DE-AC03-76SF00098. Angewandte Chemie (International Ed. in English). 40: 9822. PMID 11268101 DOI: 10.1002/1521-3773(20010316)40:6<9822::Aid-Anie9822>3.3.Co;2-I  1
2001 Broo K, Wei J, Marshall D, Brown F, Smith TJ, Johnson JE, Schneemann A, Siuzdak G. Viral capsid mobility: a dynamic conduit for inactivation. Proceedings of the National Academy of Sciences of the United States of America. 98: 2274-2277. PMID 11226229 DOI: 10.1073/Pnas.051598298  1
2001 Shen Z, Thomas JJ, Averbuj C, Broo KM, Engelhard M, Crowell JE, Finn MG, Siuzdak G. Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry. Analytical Chemistry. 73: 612-9. PMID 11217770 DOI: 10.1021/Ac000746F  1
2001 Fuerstenau SD, Benner WH, Thomas JJ, Brugidou C, Bothner B, Siuzdak G. Mass Spectrometry of an Intact Virus The authors gratefully acknowledge Jennifer Boydston for her helpful comments and suggestions. G.S. is grateful for support from the NIH (GM55775). The work at LBL was supported by the Director, Office of Energy Research, Office of Health and Environmental Research, Human Genome Program, U.S. Department of Energy under contract number DE-AC03-76SF00098. Angewandte Chemie (International Ed. in English). 40: 541-544. PMID 11180363 DOI: 10.1002/1521-3773(20010202)40:3<541::AID-ANIE541>3.0.CO;2-K  1
2001 Shen Z, Yao S, Crowell JE, Siuzdak G, Finn MG. DIOS‐MSEED: A chip‐based method for measurement of enantiomeric excess by kinetic resolution/mass spectrometry Israel Journal of Chemistry. 41: 313-316. DOI: 10.1560/Tbxu-Fd8H-Fhm1-Nr8H  1
2000 Kriwacki RW, Siuzdak G. Probing protein-protein interactions with mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 146: 223-38. PMID 10948505 DOI: 10.1385/1-59259-045-4:223  1
2000 Bothner B, Chavez R, Wei J, Strupp C, Phung Q, Schneemann A, Siuzdak G. Monitoring enzyme catalysis with mass spectrometry Journal of Biological Chemistry. 275: 13455-13459. PMID 10788458 DOI: 10.1074/Jbc.275.18.13455  1
1999 Yang C, Gu ZW, Yang M, Lin SN, Siuzdak G, Smith CV. Identification of modified tryptophan residues in apolipoprotein B-100 derived from copper ion-oxidized low-density lipoprotein. Biochemistry. 38: 15903-8. PMID 10625456 DOI: 10.1021/Bi991464G  0.04
1999 Siuzdak G, Hollenbeck T, Bothner B. Preparative mass spectrometry with electrospray ionization Journal of Mass Spectrometry. 34: 1087-1088. PMID 10510432 DOI: 10.1002/(Sici)1096-9888(199910)34:10<1087::Aid-Jms872>3.0.Co;2-A  1
1999 Chatman K, Hollenbeck T, Hagey L, Vallee M, Purdy R, Weiss F, Siuzdak G. Nanoelectrospray mass spectrometry and precursor ion monitoring for quantitative steroid analysis and attomole sensitivity. Analytical Chemistry. 71: 2358-63. PMID 10405603 DOI: 10.1021/Ac9806411  1
1999 Wei J, Buriak JM, Siuzdak G. Desorption-ionization mass spectrometry on porous silicon. Nature. 399: 243-6. PMID 10353246 DOI: 10.1038/20400  1
1999 Takayama S, Chung SJ, Igarashi Y, Ichikawa Y, Sepp A, Lechler RI, Wu J, Hayashi T, Siuzdak G, Wong CH. Selective inhibition of β-1,4- and α-1,3-galactosyltransferases: donor sugar-nucleotide based approach Bioorganic & Medicinal Chemistry. 7: 401-409. PMID 10218835 DOI: 10.1016/S0968-0896(98)00249-1  1
1999 Tsui V, Garcia C, Cavagnero S, Siuzdak G, Dyson HJ, Wright PE. Quench-flow experiments combined with mass spectrometry show apomyoglobin folds through and obligatory intermediate. Protein Science : a Publication of the Protein Society. 8: 45-9. PMID 10210182 DOI: 10.1110/Ps.8.1.45  1
1999 Bothner B, Schneeman A, Marshall D, Reddy V, Johnson JE, Siuzdak G. Crystallographically identical virus capsids display different properties in solution Nature Structural Biology. 6: 114-116. PMID 10048920 DOI: 10.1038/5799  1
1999 Marmey P, Bothner B, Jacquot E, De Kochko A, Ong CA, Yot P, Siuzdak G, Beachy RN, Fauquet CM. Rice tungro bacilliform virus open reading frame 3 encodes a single 37- kDa coat protein Virology. 253: 319-326. PMID 9918890 DOI: 10.1006/Viro.1998.9519  1
1999 Guo J, Wu J, Siuzdak G, Finn MG. Bestimmung Von Enantiomerenuberschussen Durch Kinetische Racematspaltung Und Massenspektrometrie Angewandte Chemie. 111: 1868-1871. DOI: 10.1002/(Sici)1521-3757(19990614)111:12<1868::Aid-Ange1868>3.0.Co;2-J  1
1999 Schalley CA, Rivera JM, Martín T, Santamaría J, Siuzdak G, Rebek J. Structural examination of supramolecular architectures by electrospray ionization mass spectrometry European Journal of Organic Chemistry. 1325-1331. DOI: 10.1002/(Sici)1099-0690(199906)1999:6<1325::Aid-Ejoc1325>3.0.Co;2-6  1
1998 Owens DR, Bothner B, Phung Q, Harris K, Siuzdak G. Aspects of oligonucleotide and peptide sequencing with MALDI and electrospray mass spectrometry Bioorganic and Medicinal Chemistry. 6: 1547-1554. PMID 9801826 DOI: 10.1016/S0968-0896(98)00098-4  1
1998 Lewis JK, Bothner B, Smith TJ, Siuzdak G. Antiviral agent blocks breathing of the common cold virus Proceedings of the National Academy of Sciences of the United States of America. 95: 6774-6778. PMID 9618488 DOI: 10.1073/Pnas.95.12.6774  1
1998 Bothner B, Dong XF, Bibbs L, Johnson JE, Siuzdak G. Evidence of viral capsid dynamics using limited proteolysis mass spectrometry Journal of Biological Chemistry. 273: 673-676. PMID 9422714 DOI: 10.1074/Jbc.273.2.673  1
1997 Wu J, Takayama S, Wong CH, Siuzdak G. Quantitative Electrospray Mass Spectrometry For The Rapid Assay Of Enzyme Inhibitors Chemistry & Biology. 4: 653-657. PMID 9331404 DOI: 10.1016/S1074-5521(97)90220-9  1
1997 Wu J, Chatman K, Harris K, Siuzdak G. An automated MALDI mass spectrometry approach for optimizing cyclosporin extraction and quantitation. Analytical Chemistry. 69: 3767-71. PMID 9302875 DOI: 10.1021/Ac970276Y  1
1997 Kriwacki RW, Wu J, Tennant L, Wright PE, Siuzdak G. Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1. Journal of Chromatography. A. 777: 23-30. PMID 9297835 DOI: 10.1016/S0021-9673(97)00527-X  1
1997 Takayama S, Martin R, Wu J, Laslo K, Siuzdak G, Wong CH. Chemoenzymatic Preparation of Novel Cyclic Imine Sugars and Rapid Biological Activity Evaluation Using Electrospray Mass Spectrometry and Kinetic Analysis Journal of the American Chemical Society. 119: 8146-8151. DOI: 10.1021/Ja971695F  1
1996 Fitzgerald MC, Siuzdak G. Biochemical mass spectrometry: worth the weight? Chemistry & Biology. 3: 707-15. PMID 8939685 DOI: 10.1016/S1074-5521(96)90245-8  1
1996 Siuzdak G, Bothner B, Yeager M, Brugidou C, Fauquet CM, Hoey K, Chang CM. Mass spectrometry and viral analysis Chemistry and Biology. 3: 45-48. PMID 8807827 DOI: 10.1016/S1074-5521(96)90083-6  1
1996 Kriwacki RW, Wu J, Siuzdak G, Wright PE. Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/Cdk2 complex Journal of the American Chemical Society. 118: 5320-5321. DOI: 10.1021/Ja960752M  1
1996 Fitzgerald MC, Harris K, Shevlin CG, Siuzdak G. Direct characterization of solid phase resin-bound molecules by mass spectrometry Bioorganic and Medicinal Chemistry Letters. 6: 979-982. DOI: 10.1016/0960-894X(96)00152-7  1
1996 Chang H, Chen C, Kondo T, Siuzdak G, Sharpless KB. Asymmetric Dihydroxylation Enables Rapid Construction of Chiral Dendrimers Based on 1,2-Diols Angewandte Chemie International Edition in English. 35: 182-186. DOI: 10.1002/Anie.199601821  1
1996 Chang H, Chen C, Kondo T, Siuzdak G, Sharpless KB. Asymmetrische Dihydroxylierung zum schnellen Aufbau von chiralen Dendrimeren aus 1,2-Diolen Angewandte Chemie. 108: 202-206. DOI: 10.1002/Ange.19961080217  1
1995 Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL, Lerner RA. Chemical characterization of a family of brain lipids that induce sleep. Science (New York, N.Y.). 268: 1506-9. PMID 7770779 DOI: 10.1126/Science.7770779  1
1995 Siuzdak G. Correction: The Emergence of Mass Spectrometry in Biochemical Research Proceedings of the National Academy of Sciences of the United States of America. 92: 646. DOI: 10.1073/Pnas.92.2.646A  0.01
1995 Bothner B, Chatman K, Sarkisian M, Siuzdak G. Liquid chromatography mass spectrometry of antisense oligonucleotides Bioorganic and Medicinal Chemistry Letters. 5: 2863-2868. DOI: 10.1016/0960-894X(95)00499-J  1
1995 Siuzdak G, Bothner B. Gas-phase micelles Angewandte Chemie (International Edition in English). 34: 2053-2055. DOI: 10.1002/Anie.199520531  1
1994 Stewart JD, Krebs JF, Siuzdak G, Berdis AJ, Smithrud DB, Benkovic SJ. Dissection of an antibody-catalyzed reaction Proceedings of the National Academy of Sciences of the United States of America. 91: 7404-7409. PMID 8052597 DOI: 10.1073/Pnas.91.16.7404  1
1994 Lerner RA, Siuzdak G, Prospero-Garcia O, Henriksen SJ, Boger DL, Cravatt BF. Cerebrodiene: a brain lipid isolated from sleep-deprived cats. Proceedings of the National Academy of Sciences of the United States of America. 91: 9505-8. PMID 7937797 DOI: 10.1073/Pnas.91.20.9505  1
1994 Siuzdak G, ZhengP ZL, Rhamphal JY, Ichikawa Y, Nicolaou KC, Gaeta FCA, Chatman KS, Wong CH. Examination of the sialyl lewis X - calcium complex by electrospray mass spectrometry Bioorganic and Medicinal Chemistry Letters. 4: 2863-2866. DOI: 10.1016/S0960-894X(01)80829-5  1
1993 Rideout D, Bustamante A, Siuzdak G. Cationic drug analysis using matrix-assisted laser desorption/ionization mass spectrometry: Application to influx kinetics, multidrug resistance, and intracellular chemical change Proceedings of the National Academy of Sciences of the United States of America. 90: 10226-10229. PMID 8234281 DOI: 10.1073/Pnas.90.21.10226  1
1993 Siuzdak G, Ichikawa Y, Caulfield TJ, Munoz B, Wong CH, Nicolaou KC. Evidence of calcium(2+)-dependent carbohydrate association through ion spray mass spectrometry Journal of the American Chemical Society. 115: 2877-2881. DOI: 10.1021/Ja00060A040  1
1992 Siuzdak G, Wendeborn SV, Nicolaou K. Cationization of organometallo carbonyl compounds by fast ion bombardment International Journal of Mass Spectrometry and Ion Processes. 112: 79-91. DOI: 10.1016/0168-1176(92)87033-B  0.01
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