David G. Harrison - Publications

Affiliations: 
Medicine Vanderbilt University Medical Center, Nashville, TN, United States 

301 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 de la Visitación N, Chen W, Krishnan J, Van Beusecum JP, Amarnath V, Hennen EM, Zhao S, Saleem M, Ao M, Harrison DG, Patrick DM. Immunoproteasomal Processing of Isolevuglandin Adducts in Hypertension. Biorxiv : the Preprint Server For Biology. PMID 37383945 DOI: 10.1101/2023.04.10.536054  0.738
2022 Chen W, Van Beusecum JP, Xiao L, Patrick DM, Ao M, Zhao S, Lopez MG, Billings FT, Cavinato C, Caulk AW, Humphrey JD, Harrison DG. Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36083796 DOI: 10.1152/ajpheart.00253.2022  0.721
2022 Patrick DM, de la Visitación N, Krishnan J, Chen W, Ormseth MJ, Stein CM, Davies SS, Amarnath V, Crofford LJ, Williams JM, Zhao S, Smart CD, Dikalov S, Dikalova A, Xiao L, ... ... Harrison DG, et al. Isolevuglandins disrupt PU.1 mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus. Jci Insight. PMID 35608913 DOI: 10.1172/jci.insight.136678  0.704
2021 Van Beusecum JP, Moreno H, Harrison DG. Innate immunity and clinical hypertension. Journal of Human Hypertension. PMID 34689174 DOI: 10.1038/s41371-021-00627-z  0.72
2021 Van Beusecum JP, Ruggeri Barbaro N, Smart CD, Patrick DM, Loperena R, Zhao S, de la Visitacion N, Ao M, Xiao L, Shibao CA, Harrison DG. Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension. Circulation Research. PMID 34565181 DOI: 10.1161/CIRCRESAHA.121.319643  0.74
2021 Dikalov SI, Mayorov V, Fehrenbach D, Ao M, Panov A, Harrison DG, Dikalova A. Abstract MP01: Deacetylation Of Mitochondrial Cyclophilin D K166 Inhibits Cytokine-induced Oxidative Stress And Attenuates Hypertension Hypertension. 78. DOI: 10.1161/HYP.78.SUPPL_1.MP01  0.3
2020 Ruggeri Barbaro N, Van Beusecum J, Xiao L, do Carmo L, Pitzer A, Loperena R, Foss JD, Elijovich F, Laffer CL, Montaniel KR, Galindo CL, Chen W, Ao M, Mernaugh RL, Alsouqi A, ... ... Harrison DG, et al. Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation. Cardiovascular Research. PMID 33038226 DOI: 10.1093/Cvr/Cvaa207  0.733
2020 Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalitskaya LV, Boutaud O, Zagol-Ikapitte I, Barnett JV, Murphy MB, Subati T, Stark JM, Christopher IL, Jafarian-Kerman SR, Saleh MA, Norlander AE, Loperena R, ... ... Harrison DG, et al. Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension. Jacc. Basic to Translational Science. 5: 602-615. PMID 32613146 DOI: 10.1016/J.Jacbts.2020.04.004  0.313
2020 Xiao L, Harrison DG. Inflammation in Hypertension. The Canadian Journal of Cardiology. 36: 635-647. PMID 32389337 DOI: 10.1016/J.Cjca.2020.01.013  0.396
2020 Alexander Y, Osto E, Schmidt-Trucksäss A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Bäck M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, et al. ENDOTHELIAL FUNCTION IN CARDIOVASCULAR PRECISION MEDICINE : A POSITION PAPER ON BEHALF OF THE EUROPEAN SOCIETY OF CARDIOLOGY. Cardiovascular Research. PMID 32282914 DOI: 10.1093/Cvr/Cvaa085  0.333
2020 Madhur MS, Kirabo A, Guzik TJ, Harrison DG. From Rags to Riches: Moving Beyond RAG1 in Studies of Hypertension. Hypertension (Dallas, Tex. : 1979). 75: 930-934. PMID 32078385 DOI: 10.1161/Hypertensionaha.119.14612  0.334
2020 Xiao L, Do Carmo L, Foss JD, Chen W, Harrison DG. Sympathetic Enhancement of Memory T Cell Homing and Hypertension Sensitization. Circulation Research. PMID 31928179 DOI: 10.1161/Circresaha.119.314758  0.331
2020 Van Beusecum JP, Harrison DG. New insight sheds light as to how nitrite might reduce blood pressure height: is this alright? Cardiovascular Research. 116: 1-3. PMID 31598636 DOI: 10.1093/Cvr/Cvz248  0.695
2020 Dikalova A, Mayorov V, Xiao L, Panov A, Amarnath V, Zagol-Ikapitte I, Vergeade A, Ao M, Yermalitsky V, Nazarewicz R, Boutaud O, Lopez MG, Billings FT, Davies SS, Roberts LJ, ... Harrison DG, et al. Abstract P074: Mitochondrial Isolevuglandins Contribute To Vascular Oxidative Stress And Mitochondria-targeted Scavenger Of Isolevuglandins Reduces Mitochondrial Dysfunction And Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P074  0.315
2020 Patrick DM, de la Visitacion N, Ormseth MJ, Stein C, Davies SS, Yermalitsky VN, Crofford LJ, Williams JM, Dikalov SI, Xiao L, Van Beusecum JP, Fogo A, Kirabo A, Harrison DG. Abstract MP41: A Role Of Isolevuglandins In Systemic Lupus Erythematosus Associated Autoimmunity And Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp41  0.325
2020 Beusecum JPV, Barbaro NR, Smart CD, Patrick DM, Shibao CA, Harrison DG. Abstract MP27: Human Hypertension And Endothelial Cell Activation Promote The Formation And Activation Of Axl + Siglec-6 + Dendritic Cells Via Endothelial Release Of Growth Arrest Specific 6 Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp27  0.385
2019 Rothman AM, MacFadyen J, Thuren T, Webb A, Harrison DG, Guzik TJ, Libby P, Glynn RJ, Ridker PM. Effects of Interleukin-1β Inhibition on Blood Pressure, Incident Hypertension, and Residual Inflammatory Risk: A Secondary Analysis of CANTOS. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31884854 DOI: 10.1161/Hypertensionaha.119.13642  0.343
2019 Dikalova AE, Pandey AK, Xiao L, Arslanbaeva L, Sidorova T, Lopez MG, Billings Iv FT, Verdin E, Auwerx J, Harrison DG, Dikalov SI. Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress. Circulation Research. PMID 31852393 DOI: 10.1161/Circresaha.119.315767  0.449
2019 Xiao L, Itani HA, do Carmo LS, Carver LS, Breyer RM, Harrison DG. Central EP3 (E Prostanoid 3) Receptors Mediate Salt-Sensitive Hypertension and Immune Activation. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31679420 DOI: 10.1161/Hypertensionaha.119.13850  0.378
2019 Van Beusecum JP, Barbaro NR, McDowell Z, Aden LA, Xiao L, Pandey AK, Itani HA, Himmel LE, Harrison DG, Kirabo A. High Salt Activates CD11c Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31280647 DOI: 10.1161/Hypertensionaha.119.12761  0.744
2019 Dikalov S, Itani HA, Richmond B, Vergeade A, Rahman SMJ, Boutaud O, Blackwell T, Massion PP, Harrison DG, Dikalova AE. Tobacco Smoking Induces Cardiovascular Mitochondrial Oxidative Stress, Promotes Endothelial Dysfunction and Enhances Hypertension. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30608177 DOI: 10.1152/Ajpheart.00595.2018  0.331
2019 Dikalova A, Pandey A, Xiao L, Lopez MG, Billings FT, Verdin E, Auwerx J, Harrison DG, Dikalov S. Abstract P3018: Sirt3 Depletion in Human Essential Hypertension is Linked to Vascular Inflammation and Oxidative Stress While Endothelial Specific Sirt3 Depletion in Mice Promotes Vascular Dysfunction and Increases Hypertension Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P3018  0.424
2019 Pandey AK, Dikalova A, Loperena R, Sergey D, Hana I, Harrison D. Cd70 Is Necessary For Endothelial Nitric Oxide Synthase Expression Journal of the American College of Cardiology. 73: 2038. DOI: 10.1016/S0735-1097(19)32644-0  0.314
2018 Cześnikiewicz-Guzik M, Nosalski R, Mikolajczyk TP, Vidler F, Dohnal T, Dembowska E, Graham D, Harrison DG, Guzik TJ. Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate Angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology. PMID 30414380 DOI: 10.1111/Bph.14536  0.393
2018 Loperena R, Van Beusecum JP, Itani HA, Engel N, Laroumanie F, Xiao L, Elijovich F, Laffer CL, Gnecco JS, Noonan J, Maffia P, Jasiewicz-Honkisz B, Czesnikiewicz-Guzik M, Mikolajczyk T, Sliwa T, ... ... Harrison DG, et al. Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: Roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research. PMID 29800237 DOI: 10.1093/Cvr/Cvy112  0.748
2018 Van Beusecum JP, Harrison DG. The nerve of the spleen! Causing hypertension by placental growth factor. Cardiovascular Research. 114: 356-357. PMID 29432537 DOI: 10.1093/Cvr/Cvy029  0.694
2018 Norlander AE, Madhur MS, Harrison DG. Correction: The immunology of hypertension. The Journal of Experimental Medicine. 215: 719. PMID 29305396 DOI: 10.1084/Jem.2017177301022018C  0.316
2018 Bersi MR, Khosravi R, Wujciak AJ, Harrison DG, Humphrey JD. Differential cell-matrix mechanoadaptations and inflammation drive regional propensities to aortic fibrosis, aneurysm or dissection in hypertension. Journal of the Royal Society, Interface. 14. PMID 29118111 DOI: 10.1098/Rsif.2017.0327  0.326
2018 Chen W, Patrick DM, Barbaro NR, Bernstein KE, Bernstein KE, Roeth D, Kalkum M, Xiao L, Kirabo A, Harrison DG. Abstract P281: Artificial Dendritic Cells Identify a Major Histocompatibility Complex Class 1 Subset that Activates T Cells in Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P281  0.308
2018 Carmo LS, Xiao L, Loperena R, Elijovich F, Barbaro NR, Harrison D. Abstract P160: Hypertension is Associated With Monocytes Activation in the Blood in Mice and Humans Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P160  0.329
2018 Beusecum JPV, Barbaro NR, Loperena R, Harrison DG. Abstract 127: Axl + Siglec6 + Dendritic Cells: the Role of Salt, Stretch, and Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.127  0.34
2018 Dikalov SI, Mayorov V, Pandey A, Panov A, Itani H, Amarnath V, Mernaugh R, Boutaud O, Davies S, Oates J, Harrison DG, Dikalova A. Abstract 125: Hyperacetylation of CypD Contributes to Mitochondrial Dysfunction, Vascular Oxidative Stress and Hypertension, and Mitochondria-Targeted Isoketal Scavenger mito2HOBA Prevents CypD Hyperacetylation and Reduces Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.125  0.369
2018 Dikalova A, Pandey A, Xiao L, Itani H, Sidorova T, Verdin E, Auwerx J, Harrison DG, Dikalov SI. Abstract 060: Mitochondrial Deacetylase Sirt3 in Endothelial and Smooth Muscle Cells Protects From Vascular Dysfunction and Attenuates Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.060  0.359
2018 Patrick DM, Xiao L, Chen CW, Ao M, Kirabo A, Harrison DG. Abstract 022: Proteasome Inhibition Prevents Renal Inflammation and Hypertension by Abrogation of Dendritic Cell Autoantigen Presentation Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.022  0.34
2018 Chen W, Xiao L, Harrison D. A15205 Long term end-organ inflammation and dysfunction in mice after angiotensin II-induced hypertension Journal of Hypertension. 36. DOI: 10.1097/01.Hjh.0000548336.09432.E7  0.306
2017 Pandey AK, Singhi EK, Arroyo JP, Ikizler TA, Gould ER, Brown J, Beckman JA, Harrison DG, Moslehi J. Mechanisms of VEGF (Vascular Endothelial Growth Factor) Inhibitor-Associated Hypertension and Vascular Disease. Hypertension (Dallas, Tex. : 1979). PMID 29279311 DOI: 10.1161/Hypertensionaha.117.10271  0.372
2017 Oh YS, Berkowitz DE, Cohen RA, Figueroa CA, Harrison DG, Humphrey JD, Larson DF, Leopold JA, Mecham RP, Ruiz-Opazo N, Santhanam L, Seta F, Shyy JYJ, Sun Z, Tsao PS, et al. A Special Report on the NHLBI Initiative to Study Cellular and Molecular Mechanisms of Arterial Stiffness and Its Association With Hypertension. Circulation Research. 121: 1216-1218. PMID 29122942 DOI: 10.1161/Circresaha.117.311703  0.331
2017 Barbaro NR, Foss JD, Kryshtal DO, Tsyba N, Kumaresan S, Xiao L, Mernaugh RL, Itani HA, Loperena R, Chen W, Dikalov S, Titze JM, Knollmann BC, Harrison DG, Kirabo A. Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension. Cell Reports. 21: 1009-1020. PMID 29069584 DOI: 10.1016/J.Celrep.2017.10.002  0.349
2017 Guzik TJ, Skiba DS, Touyz RM, Harrison DG. The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovascular Research. 113: 1009-1023. PMID 28838042 DOI: 10.1093/Cvr/Cvx108  0.356
2017 Dikalova AE, Itani HA, Nazarewicz RR, McMaster WG, Flynn CR, Uzhachenko RV, Fessel JP, Gamboa JL, Harrison DG, Dikalov SI. Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension. Circulation Research. PMID 28684630 DOI: 10.1161/Circresaha.117.310933  0.418
2017 Norlander AE, Saleh MA, Pandey AK, Itani HA, Wu J, Xiao L, Kang J, Dale BL, Goleva SB, Laroumanie F, Du L, Harrison DG, Madhur MS. A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage. Jci Insight. 2. PMID 28679951 DOI: 10.1172/Jci.Insight.92801  0.392
2017 Barbaro NR, Kirabo A, Harrison DG. A New Role of Mister (MR) T in Hypertension: Mineralocorticoid Receptor, Immune System, and Hypertension. Circulation Research. 120: 1527-1529. PMID 28495982 DOI: 10.1161/Circresaha.117.310985  0.39
2017 Loperena R, Harrison DG. Oxidative Stress and Hypertensive Diseases. The Medical Clinics of North America. 101: 169-193. PMID 27884227 DOI: 10.1016/J.Mcna.2016.08.004  0.404
2016 Foss JD, Kirabo A, Harrison DG. Do High Salt Microenvironments Drive Hypertensive Inflammation? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00414.2016. PMID 27903514 DOI: 10.1152/Ajpregu.00414.2016  0.384
2016 Harrison DG, Guzik TJ. Macrophages come to mind as keys to cognitive decline Journal of Clinical Investigation. 126: 4393-4395. PMID 27841765 DOI: 10.1172/Jci91277  0.342
2016 Montaniel KR, Harrison DG. Is Hypertension a Bone Marrow Disease? Circulation. PMID 27678263 DOI: 10.1161/Circulationaha.116.024520  0.364
2016 Griendling KK, Touyz RM, Zweier JL, Dikalov S, Chilian W, Chen YR, Harrison DG, Bhatnagar A. Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. Circulation Research. PMID 27418630 DOI: 10.1161/Res.0000000000000110  0.528
2016 Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, ... ... Harrison DG, et al. National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness Building on the Current Scientific Evidence. Hypertension. PMID 27324228 DOI: 10.1161/Hypertensionaha.116.07415  0.363
2016 Itani HA, McMaster WG, Saleh MA, Nazarewicz RR, Mikolajczyk TP, Kaszuba A, Konior A, Prejbisz A, Januszewicz A, Norlander AE, Chen W, Bonami RH, Marshall AF, Poffenberger G, Weyand CM, ... ... Harrison DG, et al. Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension. PMID 27217403 DOI: 10.1161/Hypertensionaha.116.07237  0.334
2016 Itani HA, Dikalova AE, McMaster WG, Nazarewicz RR, Bikineyeva AT, Harrison DG, Dikalov SI. Mitochondrial Cyclophilin D in Vascular Oxidative Stress and Hypertension. Hypertension. PMID 27067720 DOI: 10.1161/Hypertensionaha.115.07085  0.39
2016 Bersi MR, Bellini C, Wu J, Montaniel KR, Harrison DG, Humphrey JD. Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced Hypertension. Hypertension. PMID 27001298 DOI: 10.1161/Hypertensionaha.115.06262  0.383
2016 Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, ... ... Harrison DG, et al. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circulation Research. PMID 26988069 DOI: 10.1161/Circresaha.115.308111  0.329
2016 Perrien DS, Saleh MA, Takahashi K, Madhur MS, Harrison DG, Harris RC, Takahashi T. Novel methods for microCT-based analyses of vasculature in the renal cortex reveal a loss of perfusable arterioles and glomeruli in eNOS-/- mice. Bmc Nephrology. 17: 24. PMID 26936597 DOI: 10.1186/S12882-016-0235-5  0.315
2016 Shirai T, Nazarewicz RR, Wallis BB, Yanes RE, Watanabe R, Hilhorst M, Tian L, Harrison DG, Giacomini JC, Assimes TL, Goronzy JJ, Weyand CM. The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease. The Journal of Experimental Medicine. PMID 26926996 DOI: 10.1084/Jem.20150900  0.321
2016 Mikolajczyk TP, Nosalski R, Szczepaniak P, Budzyn K, Osmenda G, Skiba D, Sagan A, Wu J, Vinh A, Marvar PJ, Guzik B, Podolec J, Drummond G, Lob HE, Harrison DG, et al. Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26873938 DOI: 10.1096/Fj.201500088R  0.382
2016 Humphrey JD, Harrison DG, Figueroa CA, Lacolley P, Laurent S. Central Artery Stiffness in Hypertension and Aging: A Problem With Cause and Consequence. Circulation Research. 118: 379-81. PMID 26846637 DOI: 10.1161/Circresaha.115.307722  0.36
2016 Harrison D. Sy 17-2 Inflammation, Immunity And Hypertension Journal of Hypertension. 34. DOI: 10.1097/01.Hjh.0000501473.77203.33  0.407
2016 Dikalova A, Uzhachenko R, Itani H, Harrison DG, Dikalov S. Inactivation of Mitochondrial Deacetylase Sirt3 Promotes Vascular Oxidative Stress, Increases Endothelial Dysfunction and Exacerbates Hypertension Free Radical Biology and Medicine. 100. DOI: 10.1016/J.Freeradbiomed.2016.10.368  0.428
2016 Mayorov V, Dikalova A, Uzhachenko R, Itani H, Vergeade A, Amarnath V, Boutaud O, Mernaugh R, Davies S, Roberts LJ, Harrison DG, Dikalov S. Scavenging of Reactive Isolevuglandins in Mitochondria Reduces Vascular Oxidative Stress and Attenuates Hypertension Free Radical Biology and Medicine. 100. DOI: 10.1016/J.Freeradbiomed.2016.10.171  0.397
2015 Wu J, Montaniel KR, Saleh MA, Xiao L, Chen W, Owens GK, Humphrey JD, Majesky MW, Paik DT, Hatzopoulos AK, Madhur MS, Harrison DG. The Origin of Matrix-Producing Cells that Contribute to Aortic Fibrosis in Hypertension. Hypertension. PMID 26693821 DOI: 10.1161/Hypertensionaha.115.06123  0.379
2015 Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, ... ... Harrison DG, et al. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of Clinical Investigation. PMID 26595812 DOI: 10.1172/Jci80761  0.423
2015 Wenzel U, Turner JE, Krebs C, Kurts C, Harrison DG, Ehmke H. Immune Mechanisms in Arterial Hypertension. Journal of the American Society of Nephrology : Jasn. PMID 26319245 DOI: 10.1681/Asn.2015050562  0.377
2015 Shah KH, Shi P, Giani JF, Janjulia T, Bernstein E, Li Y, Zhao T, Harrison DG, Bernstein KE, Shen XZ. Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension. Circulation Research. PMID 26294657 DOI: 10.1161/Circresaha.115.306539  0.374
2015 Xiao L, Kirabo A, Wu J, Saleh MA, Zhu L, Wang F, Takahashi T, Loperena R, Foss JD, Mernaugh RL, Chen W, Roberts J, Osborn JW, Itani HA, Harrison DG. Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension. Circulation Research. PMID 26156232 DOI: 10.1161/Circresaha.115.306010  0.373
2015 Itani HA, Harrison DG. Memories that last in hypertension. American Journal of Physiology. Renal Physiology. 308: F1197-F1199. PMID 25834073 DOI: 10.1152/Ajprenal.00633.2014  0.347
2015 Shirai T, Hilhorst M, Harrison DG, Goronzy JJ, Weyand CM. Macrophages in vascular inflammation--From atherosclerosis to vasculitis. Autoimmunity. 48: 139-51. PMID 25811915 DOI: 10.3109/08916934.2015.1027815  0.36
2015 Hofmeister LH, Lee SH, Norlander AE, Montaniel KR, Chen W, Harrison DG, Sung HJ. Phage-display-guided nanocarrier targeting to atheroprone vasculature. Acs Nano. 9: 4435-46. PMID 25768046 DOI: 10.1021/Acsnano.5B01048  0.322
2015 McMaster WG, Kirabo A, Madhur MS, Harrison DG. Inflammation, immunity, and hypertensive end-organ damage. Circulation Research. 116: 1022-33. PMID 25767287 DOI: 10.1161/Circresaha.116.303697  0.415
2015 Saleh MA, McMaster WG, Wu J, Norlander AE, Funt SA, Thabet SR, Kirabo A, Xiao L, Chen W, Itani HA, Michell D, Huan T, Zhang Y, Takaki S, Titze J, ... ... Harrison DG, et al. Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. The Journal of Clinical Investigation. 125: 1189-202. PMID 25664851 DOI: 10.1172/Jci76327  0.424
2015 Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA. Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Hypertension. 65: 569-76. PMID 25601932 DOI: 10.1161/Hypertensionaha.114.04975  0.317
2015 Dikalova AE, Itani HA, Nazarewicz RR, McMaster WG, Fessel JP, Gamboa JL, Harrison DG, Dikalov S. The Redox Sensitive Inactivation of Mitochondrial Sirt3, SOD2 Hyperacetylation and Complex I Superoxide Production in Endothelial Dysfunction and Hypertension Free Radical Biology and Medicine. 87. DOI: 10.1016/J.Freeradbiomed.2015.10.128  0.341
2014 Nozik-Grayck E, Woods C, Taylor JM, Benninger RK, Johnson RD, Villegas LR, Stenmark KR, Harrison DG, Majka SM, Irwin D, Farrow KN. Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L868-76. PMID 25326578 DOI: 10.1152/Ajplung.00096.2014  0.376
2014 Trott DW, Thabet SR, Kirabo A, Saleh MA, Itani H, Norlander AE, Wu J, Goldstein A, Arendshorst WJ, Madhur MS, Chen W, Li CI, Shyr Y, Harrison DG. Oligoclonal CD8+ T cells play a critical role in the development of hypertension. Hypertension. 64: 1108-15. PMID 25259750 DOI: 10.1161/Hypertensionaha.114.04147  0.316
2014 Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, ... ... Harrison DG, et al. DC isoketal-modified proteins activate T cells and promote hypertension. The Journal of Clinical Investigation. 124: 4642-56. PMID 25244096 DOI: 10.1172/Jci74084  0.367
2014 Trott DW, Harrison DG. The immune system in hypertension. Advances in Physiology Education. 38: 20-4. PMID 24585465 DOI: 10.1152/Advan.00063.2013  0.407
2014 Youn JY, Siu KL, Lob HE, Itani H, Harrison DG, Cai H. Role of vascular oxidative stress in obesity and metabolic syndrome. Diabetes. 63: 2344-55. PMID 24550188 DOI: 10.2337/Db13-0719  0.335
2014 Harrison DG. From ST segments to endothelial pathophysiology: hypercholesterolemia and endothelial superoxide production. The Journal of Clinical Investigation. 124: 473-5. PMID 24487641 DOI: 10.1172/Jci70336  0.362
2014 Wu J, Thabet SR, Kirabo A, Trott DW, Saleh MA, Xiao L, Madhur MS, Chen W, Harrison DG. Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Circulation Research. 114: 616-25. PMID 24347665 DOI: 10.1161/Circresaha.114.302157  0.374
2014 Dikalov SI, Nazarewicz RR, Bikineyeva A, Hilenski L, Lassègue B, Griendling KK, Harrison DG, Dikalova AE. Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. Antioxidants & Redox Signaling. 20: 281-94. PMID 24053613 DOI: 10.1089/Ars.2012.4918  0.408
2013 Wiig H, Schröder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N, Dahlmann A, Brenner S, Tenstad O, Nurmi H, Mervaala E, ... ... Harrison DG, et al. Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. The Journal of Clinical Investigation. 123: 2803-15. PMID 23722907 DOI: 10.1172/Jci60113  0.343
2013 Madhur MS, Harrison DG. Senescent T cells and hypertension: new ideas about old cells. Hypertension (Dallas, Tex. : 1979). 62: 13-5. PMID 23716580 DOI: 10.1161/Hypertensionaha.113.01410  0.391
2013 Itani HA, Dikalov S, Harrison DG. Knock, knock: who's there?: Nox1. Circulation. 127: 1850-2. PMID 23564667 DOI: 10.1161/Circulationaha.113.002564  0.386
2013 Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM. Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism. American Journal of Physiology. Renal Physiology. 304: F1390-7. PMID 23515718 DOI: 10.1152/Ajprenal.00292.2012  0.344
2013 Harrison DG. The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension. Journal of the American Society of Hypertension : Jash. 7: 68-74. PMID 23321405 DOI: 10.1016/J.Jash.2012.11.007  0.344
2013 Lob HE, Schultz D, Marvar PJ, Davisson RL, Harrison DG. Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension. 61: 382-7. PMID 23248154 DOI: 10.1161/Hypertensionaha.111.00546  0.409
2012 Madhur MS, Harrison DG. Synapses, signals, CDs, and cytokines: interactions of the autonomic nervous system and immunity in hypertension. Circulation Research. 111: 1113-6. PMID 23065340 DOI: 10.1161/Circresaha.112.278408  0.442
2012 Hasty AH, Harrison DG. Endoplasmic reticulum stress and hypertension - a new paradigm? The Journal of Clinical Investigation. 122: 3859-61. PMID 23064369 DOI: 10.1172/Jci65173  0.346
2012 Marvar PJ, Harrison DG. Stress-dependent hypertension and the role of T lymphocytes. Experimental Physiology. 97: 1161-7. PMID 22941978 DOI: 10.1113/Expphysiol.2011.061507  0.36
2012 Harrison DG, Marvar PJ, Titze JM. Vascular inflammatory cells in hypertension. Frontiers in Physiology. 3: 128. PMID 22586409 DOI: 10.3389/Fphys.2012.00128  0.421
2012 Nagamani SC, Campeau PM, Shchelochkov OA, Premkumar MH, Guse K, Brunetti-Pierri N, Chen Y, Sun Q, Tang Y, Palmer D, Reddy AK, Li L, Slesnick TC, Feig DI, Caudle S, ... Harrison D, et al. Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria. American Journal of Human Genetics. 90: 836-46. PMID 22541557 DOI: 10.1016/J.Ajhg.2012.03.018  0.31
2012 Youn JY, Wang T, Blair J, Laude KM, Oak JH, McCann LA, Harrison DG, Cai H. Endothelium-specific sepiapterin reductase deficiency in DOCA-salt hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 302: H2243-9. PMID 22467312 DOI: 10.1152/Ajpheart.00835.2011  0.4
2012 Osgood MJ, Harrison DG, Sexton KW, Hocking KM, Voskresensky IV, Komalavilas P, Cheung-Flynn J, Guzman RJ, Brophy CM. Role of the renin-angiotensin system in the pathogenesis of intimal hyperplasia: therapeutic potential for prevention of vein graft failure? Annals of Vascular Surgery. 26: 1130-44. PMID 22445245 DOI: 10.1016/J.Avsg.2011.12.001  0.352
2012 Cowley AW, Nadeau JH, Baccarelli A, Berecek K, Fornage M, Gibbons GH, Harrison DG, Liang M, Nathanielsz PW, O'Connor DT, Ordovas J, Peng W, Soares MB, Szyf M, Tolunay HE, et al. Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. Hypertension. 59: 899-905. PMID 22431584 DOI: 10.1161/Hypertensionaha.111.190116  0.347
2012 Marvar PJ, Vinh A, Thabet S, Lob HE, Geem D, Ressler KJ, Harrison DG. T lymphocytes and vascular inflammation contribute to stress-dependent hypertension. Biological Psychiatry. 71: 774-82. PMID 22361077 DOI: 10.1016/J.Biopsych.2012.01.017  0.38
2011 Major AS, Harrison DG. What fans the fire: insights into mechanisms of inflammation in atherosclerosis and diabetes mellitus. Circulation. 124: 2809-11. PMID 22184043 DOI: 10.1161/Circulationaha.111.070565  0.349
2011 Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, ... ... Harrison DG, et al. Requirement of argininosuccinate lyase for systemic nitric oxide production. Nature Medicine. 17: 1619-26. PMID 22081021 DOI: 10.1038/Nm.2544  0.307
2011 Lob HE, Vinh A, Li L, Blinder Y, Offermanns S, Harrison DG. Role of Vascular Extracellular Superoxide Dismutase in Hypertension Hypertension. 58: 232-239. PMID 21730294 DOI: 10.1161/Hypertensionaha.111.172718  0.43
2011 Li L, Du Y, Chen W, Fu H, Harrison DG. A novel high-throughput screening assay for discovery of molecules that increase cellular tetrahydrobiopterin. Journal of Biomolecular Screening. 16: 836-44. PMID 21693765 DOI: 10.1177/1087057111411088  0.306
2011 Li L, Chen W, Rezvan A, Jo H, Harrison DG. Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1547-54. PMID 21512164 DOI: 10.1161/Atvbaha.111.226456  0.347
2011 Madhur MS, Funt SA, Li L, Vinh A, Chen W, Lob HE, Iwakura Y, Blinder Y, Rahman A, Quyyumi AA, Harrison DG. Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1565-72. PMID 21474820 DOI: 10.1161/Atvbaha.111.227629  0.315
2011 Chen W, Li L, Brod T, Saeed O, Thabet S, Jansen T, Dikalov S, Weyand C, Goronzy J, Harrison DG. Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation. The Journal of Biological Chemistry. 286: 13846-51. PMID 21343293 DOI: 10.1074/Jbc.M110.191023  0.327
2011 Marvar PJ, Lob H, Vinh A, Zarreen F, Harrison DG. The central nervous system and inflammation in hypertension. Current Opinion in Pharmacology. 11: 156-61. PMID 21196131 DOI: 10.1016/J.Coph.2010.12.001  0.392
2011 Harrison DG, Guzik TJ, Lob HE, Madhur MS, Marvar PJ, Thabet SR, Vinh A, Weyand CM. Inflammation, immunity, and hypertension. Hypertension (Dallas, Tex. : 1979). 57: 132-40. PMID 21149826 DOI: 10.1161/Hypertensionaha.110.163576  0.328
2011 Harrison DG, Chen W, Dikalov S, Li L. Regulation of endothelial cell tetrahydrobiopterin pathophysiological and therapeutic implications. Advances in Pharmacology (San Diego, Calif.). 60: 107-32. PMID 21081217 DOI: 10.1016/B978-0-12-385061-4.00005-2  0.377
2011 Birari R, Villegas L, Locke J, Harrison D, Nozik-Grayck E. Conditional Knock Down of Extracellular Superoxide Dismutase in Smooth Muscle Cells Augments Chronic Hypoxic Pulmonary Hypertension Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.345  0.304
2010 Vinh A, Chen W, Blinder Y, Weiss D, Taylor WR, Goronzy JJ, Weyand CM, Harrison DG, Guzik TJ. Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Circulation. 122: 2529-37. PMID 21126972 DOI: 10.1161/Circulationaha.109.930446  0.356
2010 Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK. Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H673-9. PMID 20639222 DOI: 10.1152/Ajpheart.00242.2010  0.379
2010 Nam D, Ni CW, Rezvan A, Suo J, Budzyn K, Llanos A, Harrison DG, Giddens DP, Jo H. A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium. Journal of Visualized Experiments : Jove. PMID 20613706 DOI: 10.3791/1861  0.319
2010 Marvar PJ, Thabet SR, Guzik TJ, Lob HE, McCann LA, Weyand C, Gordon FJ, Harrison DG. Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circulation Research. 107: 263-70. PMID 20558826 DOI: 10.1161/Circresaha.110.217299  0.371
2010 Schneider MP, Sullivan JC, Wach PF, Boesen EI, Yamamoto T, Fukai T, Harrison DG, Pollock DM, Pollock JS. Protective role of extracellular superoxide dismutase in renal ischemia/reperfusion injury. Kidney International. 78: 374-81. PMID 20505656 DOI: 10.1038/Ki.2010.141  0.317
2010 Dikalova AE, Bikineyeva AT, Budzyn K, Nazarewicz RR, McCann L, Lewis W, Harrison DG, Dikalov SI. Therapeutic Targeting of Mitochondrial Superoxide in Hypertension Circulation Research. 107: 106-116. PMID 20448215 DOI: 10.1161/Circresaha.109.214601  0.392
2010 Harrison DG, Vinh A, Lob H, Madhur MS. Role of the adaptive immune system in hypertension. Current Opinion in Pharmacology. 10: 203-207. PMID 20167535 DOI: 10.1016/J.Coph.2010.01.006  0.383
2010 Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC. Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Circulation. 121: 519-28. PMID 20083682 DOI: 10.1161/Circulationaha.109.883777  0.364
2010 Madhur MS, Lob HE, McCann LA, Iwakura Y, Blinder Y, Guzik TJ, Harrison DG. Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction Hypertension. 55: 500-507. PMID 20038749 DOI: 10.1161/Hypertensionaha.109.145094  0.336
2010 Lob HE, Marvar PJ, Guzik TJ, Sharma S, McCann LA, Weyand C, Gordon FJ, Harrison DG. Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system. Hypertension (Dallas, Tex. : 1979). 55: 277-83, 6p following. PMID 20008675 DOI: 10.1161/Hypertensionaha.109.142646  0.419
2010 Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W. GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide. Circulation Research. 106: 328-36. PMID 19926872 DOI: 10.1161/Circresaha.109.210658  0.344
2010 Silberman GA, Fan THM, Jiao Z, Boulden BM, Widder J, Fredd S, Dikalov S, Harrison DG, Lovelock JD, Xiao HD, Wolska BM, Liu H, Dudley SC, Bernstein KE. Reply to letter regarding article, uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction Circulation. 122: e559. DOI: 10.1161/Circulationaha.110.962183  0.355
2010 Dikalova A, Góngora MC, Harrison D, Lambeth D, Dikalov S, Griendling K. Supplementation with Tetrahydrobiopterin Reverse Impaired Endothelium-Dependent Relaxation and eNOS Uncoupling Induced by Nox1 Overexpression in Vascular Smooth Muscle Free Radical Biology and Medicine. 49: S180. DOI: 10.1016/J.Freeradbiomed.2010.10.512  0.316
2010 Dikalov S, Dikalova A, Nazarewicz R, Bikineyeva A, Mayorov V, Hilenski L, Lassègue B, Harrison D, Griendling K. Role of Nox2-induced Reverse Electron Transfer in Production of Mitochondrial Reactive Oxygen Species, Endothelial Dysfunction and Hypertension Free Radical Biology and Medicine. 49: S20. DOI: 10.1016/J.Freeradbiomed.2010.10.021  0.333
2009 Shuvaev VV, Christofidou-Solomidou M, Bhora F, Laude K, Cai H, Dikalov S, Arguiri E, Solomides CC, Albelda SM, Harrison DG, Muzykantov VR. Targeted detoxification of selected reactive oxygen species in the vascular endothelium. The Journal of Pharmacology and Experimental Therapeutics. 331: 404-11. PMID 19692634 DOI: 10.1124/Jpet.109.156877  0.395
2009 Nam D, Ni CW, Rezvan A, Suo J, Budzyn K, Llanos A, Harrison D, Giddens D, Jo H. Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1535-43. PMID 19684185 DOI: 10.1152/Ajpheart.00510.2009  0.305
2009 Marvar PJ, Gordon FJ, Harrison DG. Blood pressure control: salt gets under your skin. Nature Medicine. 15: 487-8. PMID 19424204 DOI: 10.1038/Nm0509-487  0.306
2009 Collins AR, Lyon CJ, Xia X, Liu JZ, Tangirala RK, Yin F, Boyadjian R, Bikineyeva A, Praticò D, Harrison DG, Hsueh WA. Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circulation Research. 104: e42-54. PMID 19265038 DOI: 10.1161/Circresaha.108.188771  0.336
2009 Jones R, Baker MB, Weber M, Harrison DG, Bao G, Searles CD. Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA. American Journal of Physiology. Cell Physiology. 296: C498-504. PMID 19109525 DOI: 10.1152/Ajpcell.00462.2008  0.347
2009 Hoch NE, Guzik TJ, Chen W, Deans T, Maalouf SA, Gratze P, Weyand C, Harrison DG. Regulation of T-cell function by endogenously produced angiotensin II. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R208-16. PMID 19073907 DOI: 10.1152/Ajpregu.90521.2008  0.344
2008 Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG. Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease. Journal of the American College of Cardiology. 52: 1803-9. PMID 19022160 DOI: 10.1016/J.Jacc.2008.07.063  0.32
2008 Daiber A, Harrison DG, Münzel T. Doubt about an essential role for constitutive nitric oxide synthase in nitroglycerin-mediated vasodilation Proceedings of the National Academy of Sciences of the United States of America. 105. PMID 19020103 DOI: 10.1073/Pnas.0807190105  0.319
2008 Harrison DG, Guzik TJ, Goronzy J, Weyand C. Is hypertension an immunologic disease? Current Cardiology Reports. 10: 464-469. PMID 18950555 DOI: 10.1007/S11886-008-0073-6  0.385
2008 Qin Z, Gongora MC, Ozumi K, Itoh S, Akram K, Ushio-Fukai M, Harrison DG, Fukai T. Role of Menkes ATPase in angiotensin II-induced hypertension: a key modulator for extracellular superoxide dismutase function. Hypertension. 52: 945-51. PMID 18768397 DOI: 10.1161/Hypertensionaha.108.116467  0.418
2008 Dikalov SI, Dikalova AE, Bikineyeva AT, Schmidt HH, Harrison DG, Griendling KK. Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Free Radical Biology & Medicine. 45: 1340-51. PMID 18760347 DOI: 10.1016/J.Freeradbiomed.2008.08.013  0.334
2008 Ashfaq S, Abramson JL, Jones DP, Rhodes SD, Weintraub WS, Hooper WC, Vaccarino V, Alexander RW, Harrison DG, Quyyumi AA. Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults. Hypertension. 52: 80-5. PMID 18504327 DOI: 10.1161/Hypertensionaha.107.097386  0.358
2008 Chen W, Bacanamwo M, Harrison DG. Activation of p300 Histone Acetyltransferase Activity Is an Early Endothelial Response to Laminar Shear Stress and Is Essential for Stimulation of Endothelial Nitric-oxide Synthase mRNA Transcription* Journal of Biological Chemistry. 283: 16293-16298. PMID 18397880 DOI: 10.1074/Jbc.M801803200  0.304
2008 Porkert M, Sher S, Reddy U, Cheema F, Niessner C, Kolm P, Jones DP, Hooper C, Taylor WR, Harrison D, Quyyumi AA. Tetrahydrobiopterin: a novel antihypertensive therapy. Journal of Human Hypertension. 22: 401-7. PMID 18322548 DOI: 10.1038/Sj.Jhh.1002329  0.33
2008 Doughan AK, Harrison DG, Dikalov SI. Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction Circulation Research. 102: 488-496. PMID 18096818 DOI: 10.1161/Circresaha.107.162800  0.363
2008 Gongora MC, Harrison DG. Sad Heart From No SOD Hypertension. 51: 28-30. PMID 18025292 DOI: 10.1161/Hypertensionaha.107.101162  0.365
2008 Harrison DG. O76. Role of the T cell in modulation of blood pressure and vascular function in hypertension Nitric Oxide. 19: 37-38. DOI: 10.1016/J.Niox.2008.06.077  0.366
2008 Silberman GA, Liu H, Jiao Z, Xiao HD, Boulden BM, Widder J, Fredd S, Bernstein KE, Dikalov S, Harrison DG, Tai-Hwang MF, Dudley SC. Uncoupled Nitric Oxide Synthase Leads to Diastolic Dysfunction Irrespective of Blood Pressure Journal of Cardiac Failure. 14: S24. DOI: 10.1016/J.Cardfail.2008.06.081  0.353
2007 Harrison DG, Gongora MC. Oxidative Stress and Hypertension Medical Clinics of North America. 93: 621-635. PMID 19427495 DOI: 10.1016/J.Mcna.2009.02.015  0.415
2007 Cai H, Dikalov S, Griendling KK, Harrison DG. Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity. Methods in Molecular Medicine. 139: 293-311. PMID 18287681 DOI: 10.1007/978-1-59745-571-8_20  0.382
2007 Guzik TJ, Hoch NE, Brown KA, McCann LA, Rahman A, Dikalov S, Goronzy J, Weyand CM, Harrison DG. Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction Journal of Experimental Medicine. 204: 2449-2460. PMID 17875676 DOI: 10.1084/Jem.20070657  0.407
2007 Widder JD, Chen W, Li L, Dikalov S, Thöny B, Hatakeyama K, Harrison DG. Regulation of Tetrahydrobiopterin Biosynthesis by Shear Stress Circulation Research. 101: 830-838. PMID 17704208 DOI: 10.1161/Circresaha.107.153809  0.316
2007 Guzik TJ, Harrison DG. Endothelial NF-κB As a Mediator of Kidney Damage: The Missing Link Between Systemic Vascular and Renal Disease? Circulation Research. 101: 227-229. PMID 17673681 DOI: 10.1161/Circresaha.107.158295  0.387
2007 Dikalov S, Griendling KK, Harrison DG. Measurement of reactive oxygen species in cardiovascular studies. Hypertension. 49: 717-27. PMID 17296874 DOI: 10.1161/01.Hyp.0000258594.87211.6B  0.335
2007 Widder JD, Guzik TJ, Mueller CF, Clempus RE, Schmidt HH, Dikalov SI, Griendling KK, Jones DP, Harrison DG. Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 762-8. PMID 17272743 DOI: 10.1161/01.Atv.0000259298.11129.A2  0.409
2007 San Martín A, Du P, Dikalova A, Lassègue B, Aleman M, Góngora MC, Brown K, Joseph G, Harrison DG, Taylor WR, Jo H, Griendling KK. Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2073-82. PMID 17237245 DOI: 10.1152/Ajpheart.00943.2006  0.339
2006 Ramchandran R, Takezako T, Saad Y, Stull L, Fink B, Yamada H, Dikalov S, Harrison DG, Moravec C, Karnik SS. Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response. Proceedings of the National Academy of Sciences of the United States of America. 103: 19087-92. PMID 17148616 DOI: 10.1073/Pnas.0602715103  0.413
2006 Boulden BM, Widder JD, Allen JC, Smith DA, Al-Baldawi RN, Harrison DG, Dikalov SI, Jo H, Dudley SC. Early determinants of H2O2-induced endothelial dysfunction. Free Radical Biology & Medicine. 41: 810-7. PMID 16895801 DOI: 10.1016/J.Freeradbiomed.2006.05.030  0.336
2006 Gongora MC, Qin Z, Laude K, Kim HW, McCann L, Folz JR, Dikalov S, Fukai T, Harrison DG. Role of extracellular superoxide dismutase in hypertension. Hypertension. 48: 473-81. PMID 16864745 DOI: 10.1161/01.Hyp.0000235682.47673.Ab  0.391
2006 Miriyala S, Gongora Nieto MC, Mingone C, Smith D, Dikalov S, Harrison DG, Jo H. Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Circulation. 113: 2818-25. PMID 16769910 DOI: 10.1161/Circulationaha.106.611822  0.419
2006 Guzik TJ, Harrison DG. Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discovery Today. 11: 524-533. PMID 16713904 DOI: 10.1016/J.Drudis.2006.04.003  0.357
2006 Harrison DG, Widder J, Grumbach I, Chen W, Weber M, Searles C. Endothelial mechanotransduction, nitric oxide and vascular inflammation. Journal of Internal Medicine. 259: 351-363. PMID 16594903 DOI: 10.1111/J.1365-2796.2006.01621.X  0.383
2006 Modlinger P, Chabrashvili T, Gill PS, Mendonca M, Harrison DG, Griendling KK, Li M, Raggio J, Wellstein A, Chen Y, Welch WJ, Wilcox CS. RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response. Hypertension. 47: 238-44. PMID 16391171 DOI: 10.1161/01.Hyp.0000200023.02195.73  0.361
2006 Doughan AK, Harrison DG, Dikalov SI. Molecular mechanisms of angiotensin II mediated mitochondrial dysfunction in vascular endothelial cells Mitochondrion. 6: 21. DOI: 10.1016/J.Mito.2006.08.051  0.357
2006 Landmesser U, Harrison DG, Drexler H. Oxidant stress—a major cause of reduced endothelial nitric oxide availability in cardiovascular disease European Journal of Clinical Pharmacology. 62: 13-19. DOI: 10.1007/S00228-005-0012-Z  0.429
2005 Guzik TJ, Sadowski J, Guzik B, Jopek A, Kapelak B, Przybylowski P, Wierzbicki K, Korbut R, Harrison DG, Channon KM. Coronary artery superoxide production and nox isoform expression in human coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 333-9. PMID 16293794 DOI: 10.1161/01.Atv.0000196651.64776.51  0.304
2005 Mueller CFH, Widder JD, McNally JS, McCann L, Jones DP, Harrison DG. The Role of the Multidrug Resistance Protein-1 in Modulation of Endothelial Cell Oxidative Stress Circulation Research. 97: 637-644. PMID 16123331 DOI: 10.1161/01.Res.0000183734.21112.B7  0.417
2005 Grumbach IM, Chen W, Mertens SA, Harrison DG. A negative feedback mechanism involving nitric oxide and nuclear factor kappa-B modulates endothelial nitric oxide synthase transcription. Journal of Molecular and Cellular Cardiology. 39: 595-603. PMID 16099468 DOI: 10.1016/J.Yjmcc.2005.06.012  0.382
2005 Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols : Implications for uncoupling endothelial nitric oxide synthase Biochemical Pharmacology. 70: 343-354. PMID 15963955 DOI: 10.1016/J.Bcp.2005.05.009  0.329
2005 Weber M, Hagedorn CH, Harrison DG, Searles CD. Laminar shear stress and 3' polyadenylation of eNOS mRNA. Circulation Research. 96: 1161-8. PMID 15905462 DOI: 10.1161/01.Res.0000170651.72198.Fa  0.315
2005 Jeney V, Itoh S, Wendt M, Gradek Q, Ushio-Fukai M, Harrison DG, Fukai T. Role of antioxidant-1 in extracellular superoxide dismutase function and expression. Circulation Research. 96: 723-9. PMID 15761197 DOI: 10.1161/01.Res.0000162001.57896.66  0.311
2005 Lauer N, Suvorava T, Rüther U, Jacob R, Meyer W, Harrison DG, Kojda G. Critical involvement of hydrogen peroxide in exercise-induced up-regulation of endothelial NO synthase. Cardiovascular Research. 65: 254-262. PMID 15621054 DOI: 10.1016/J.Cardiores.2004.09.010  0.322
2005 Laude K, Cai H, Fink B, Hoch N, Weber DS, McCann L, Kojda G, Fukai T, Schmidt HH, Dikalov S, Ramasamy S, Gamez G, Griendling KK, Harrison DG. Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H7-12. PMID 15471976 DOI: 10.1152/Ajpheart.00637.2004  0.376
2005 Weber DS, Rocic P, Mellis AM, Laude K, Lyle AN, Harrison DG, Griendling KK. Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 288: H37-42. PMID 15345488 DOI: 10.1152/Ajpheart.00638.2004  0.357
2004 Mueller CFH, Laude K, McNally JS, Harrison DG. Redox Mechanisms in Blood Vessels Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 274-278. PMID 15514203 DOI: 10.1161/01.Atv.0000149143.04821.Eb  0.376
2004 Fink B, Laude K, McCann L, Doughan A, Harrison DG, Dikalov S. Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay. American Journal of Physiology-Cell Physiology. 287. PMID 15306539 DOI: 10.1152/Ajpcell.00028.2004  0.316
2004 Son SM, Whalin MK, Harrison DG, Taylor WR, Griendling KK. Oxidative stress and diabetic vascular complications. Current Diabetes Reports. 4: 247-52. PMID 15265465 DOI: 10.1007/S11892-004-0075-8  0.325
2004 Cai H, McNally JS, Weber M, Harrison DG. Oscillatory shear stress upregulation of endothelial nitric oxide synthase requires intracellular hydrogen peroxide and CaMKII Journal of Molecular and Cellular Cardiology. 37: 121-125. PMID 15242742 DOI: 10.1016/J.Yjmcc.2004.04.012  0.326
2004 Khatri JJ, Johnson C, Magid R, Lessner SM, Laude KM, Dikalov SI, Harrison DG, Sung HJ, Rong Y, Galis ZS. Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma. Circulation. 109: 520-5. PMID 14744973 DOI: 10.1161/01.Cir.0000109698.70638.2B  0.33
2004 Davis ME, Grumbach IM, Fukai T, Cutchins A, Harrison DG. Shear stress regulates endothelial nitric-oxide synthase promoter activity through nuclear factor kappaB binding. The Journal of Biological Chemistry. 279: 163-8. PMID 14570928 DOI: 10.1074/Jbc.M307528200  0.336
2003 Boo YC, Sorescu GP, Bauer PM, Fulton D, Kemp BE, Harrison DG, Sessa WC, Jo H. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. Free Radical Biology & Medicine. 35: 729-41. PMID 14583337 DOI: 10.1016/S0891-5849(03)00397-6  0.311
2003 Cai H, Griendling KK, Harrison DG. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends in Pharmacological Sciences. 24: 471-8. PMID 12967772 DOI: 10.1016/S0165-6147(03)00233-5  0.345
2003 Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S, Giddens DP, Griendling KK, Harrison DG, Jo H. Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. The Journal of Biological Chemistry. 278: 47291-8. PMID 12958309 DOI: 10.1074/Jbc.M305150200  0.338
2003 McNally JS, Davis ME, Giddens DP, Saha A, Hwang J, Dikalov S, Jo H, Harrison DG. Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2290-7. PMID 12958034 DOI: 10.1152/Ajpheart.00515.2003  0.352
2003 Harrison DG, Cai H, Landmesser U, Griendling KK. Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 4: 51-61. PMID 12806586 DOI: 10.3317/Jraas.2003.014  0.411
2003 Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. The Journal of Clinical Investigation. 111: 1201-9. PMID 12697739 DOI: 10.1172/Jci14172  0.428
2003 Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. Journal of Biological Chemistry. 278: 22546-22554. PMID 12692136 DOI: 10.1074/Jbc.M302227200  0.357
2003 Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of oxidative stress in atherosclerosis. The American Journal of Cardiology. 91: 7A-11A. PMID 12645638 DOI: 10.1016/S0002-9149(02)03144-2  0.413
2003 Spiekermann S, Landmesser U, Dikalov S, Bredt M, Gamez G, Tatge H, Reepschläger N, Hornig B, Drexler H, Harrison DG. Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation. 107: 1383-9. PMID 12642358 DOI: 10.1161/01.Cir.0000056762.69302.46  0.356
2003 Davis ME, Cai H, McCann L, Fukai T, Harrison DG. Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1449-53. PMID 12595302 DOI: 10.1152/Ajpheart.00918.2002  0.327
2003 Ashfag S, Abramson Jl, Rhodes SD, Beinart SC, Jurkovitz C, Williams JK, Vaccarino V, Quyyumi AA, Weintraub WS, Harrison DG. The relationship of oxidative stress to vascular health in humans Journal of the American College of Cardiology. 41: 272. DOI: 10.1016/S0735-1097(03)82276-3  0.311
2002 Landmesser U, Spiekermann S, Dikalov S, Tatge H, Wilke R, Kohler C, Harrison DG, Hornig B, Drexler H. Vascular Oxidative Stress and Endothelial Dysfunction in Patients With Chronic Heart Failure Role of Xanthine-Oxidase and Extracellular Superoxide Dismutase Circulation. 106: 3073-3078. PMID 12473554 DOI: 10.1161/01.Cir.0000041431.57222.Af  0.371
2002 Münzel T, Afanas’ev IB, Kleschyov AL, Harrison DG. Detection of Superoxide in Vascular Tissue Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1761-1768. PMID 12426202 DOI: 10.1161/01.Atv.0000034022.11764.Ec  0.311
2002 Cai H, Li Z, Dikalov S, Holland SM, Hwang J, Jo H, Dudley SC, Harrison DG. NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II. The Journal of Biological Chemistry. 277: 48311-7. PMID 12377764 DOI: 10.1074/Jbc.M208884200  0.361
2002 Landmesser U, Cai H, Dikalov S, McCann L, Hwang J, Jo H, Holland SM, Harrison DG. Role Of P47(Phox) In Vascular Oxidative Stress And Hypertension Caused By Angiotensin Ii Hypertension. 40: 511-515. PMID 12364355 DOI: 10.1161/01.Hyp.0000032100.23772.98  0.406
2002 Hink HU, Santanam N, Dikalov S, McCann L, Nguyen AD, Parthasarathy S, Harrison DG, Fukai T. Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1402-8. PMID 12231557 DOI: 10.1161/01.Atv.0000027524.86752.02  0.309
2002 Braddon LG, Karoyli D, Harrison DG, Nerem RM. Maintenance of a functional endothelial cell monolayer on a fibroblast/polymer substrate under physiologically relevant shear stress conditions. Tissue Engineering. 8: 695-708. PMID 12202008 DOI: 10.1089/107632702760240607  0.309
2002 Fukai T, Folz RJ, Landmesser U, Harrison DG. Extracellular superoxide dismutase and cardiovascular disease. Cardiovascular Research. 55: 239-49. PMID 12123763 DOI: 10.1016/S0008-6363(02)00328-0  0.378
2002 Dikalov S, Landmesser U, Harrison DG. Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase. Journal of Biological Chemistry. 277: 25480-25485. PMID 11983711 DOI: 10.1074/Jbc.M203271200  0.359
2002 Nickenig G, Harrison DG. The AT1-Type Angiotensin Receptor in Oxidative Stress and Atherogenesis Circulation. 105: 530-536. PMID 11815439 DOI: 10.1161/Hc0402.102619  0.355
2002 Nickenig G, Harrison DG. The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis. Circulation. 105: 393-396. PMID 11804998 DOI: 10.1161/Hc0302.102618  0.361
2001 Griendling KK, Harrison DG. Out, damned dot: studies of the NADPH oxidase in atherosclerosis. The Journal of Clinical Investigation. 108: 1423-4. PMID 11714732 DOI: 10.1172/Jci14453  0.373
2001 Landmesser U, Harrison DG. Oxidative stress and vascular damage in hypertension. Coronary Artery Disease. 12: 455-461. PMID 11696684 DOI: 10.1097/00019501-200109000-00004  0.375
2001 Cai H, Davis ME, Drummond GR, Harrison DG. Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2+)/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1571-6. PMID 11597928 DOI: 10.1161/Hq1001.097028  0.317
2001 Uemura S, Matsushita H, Li W, Glassford AJ, Asagami T, Lee K, Harrison DG, Tsao PS. Diabetes Mellitus Enhances Vascular Matrix Metalloproteinase Activity: Role of Oxidative Stress Circulation Research. 88: 1291-1298. PMID 11420306 DOI: 10.1161/Hh1201.092042  0.315
2001 Sorescu D, Somers MJ, Lassègue B, Grant S, Harrison DG, Griendling KK. Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells. Free Radical Biology & Medicine. 30: 603-12. PMID 11295358 DOI: 10.1016/S0891-5849(00)00507-4  0.319
2001 Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, Tarpey M, Fukai T, Harrison DG. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation. 103: 1282-8. PMID 11238274 DOI: 10.1161/01.Cir.103.9.1282  0.397
2001 Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchkov M, Thaiss F, Stahl RA, Warnholtz A, Meinertz T, Griendling K, Harrison DG, Forstermann U, Munzel T. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circulation Research. 88: E14-22. PMID 11157681 DOI: 10.1161/01.Res.88.2.E14  0.369
2001 Davis ME, Harrison DG. Cracking down on caveolin: role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in modulating edothelial cell nitric oxide production. Circulation. 103: 2-4. PMID 11136674 DOI: 10.1161/01.Cir.103.1.2  0.386
2001 Landmesser U, Harrison DG. Oxidant Stress as a Marker for Cardiovascular Events Ox Marks the Spot Circulation. 104: 2638-2640. DOI: 10.1161/Circ.104.22.2638  0.402
2000 Somers MJ, Burchfield JS, Harrison DG. Evidence for a NADH/NADPH oxidase in human umbilical vein endothelial cells using electron spin resonance. Antioxidants & Redox Signaling. 2: 779-787. PMID 11213482 DOI: 10.1089/Ars.2000.2.4-779  0.329
2000 Cai H, Harrison DG. Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress Circulation Research. 87: 840-844. PMID 11073878 DOI: 10.1161/01.Res.87.10.840  0.402
2000 Schultz D, Harrison DG. Quest for fire: seeking the source of pathogenic oxygen radicals in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1412-1413. PMID 10845849 DOI: 10.1161/01.Atv.20.6.1412  0.355
2000 Fukai T, Siegfried MR, Ushio-Fukai M, Cheng Y, Kojda G, Harrison DG. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. The Journal of Clinical Investigation. 105: 1631-9. PMID 10841522 DOI: 10.1172/Jci9551  0.345
2000 Somers MJ, Mavromatis K, Galis ZS, Harrison DG. Vascular Superoxide Production and Vasomotor Function in Hypertension Induced by Deoxycorticosterone Acetate–Salt Circulation. 101: 1722-1728. PMID 10758056 DOI: 10.1161/01.Cir.101.14.1722  0.428
2000 Drummond GR, Cai H, Davis ME, Ramasamy S, Harrison DG. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circulation Research. 86: 347-54. PMID 10679488 DOI: 10.1161/01.Res.86.3.347  0.346
1999 Somers MJ, Harrison DG. Reactive oxygen species and the control of vasomotor tone. Current Hypertension Reports. 1: 102-108. PMID 10981049 DOI: 10.1007/S11906-999-0080-Z  0.412
1999 Kojda G, Harrison D. Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure Cardiovascular Research. 43: 562-571. PMID 10690328 DOI: 10.1016/S0008-6363(99)00169-8  0.418
1999 Shah AM, Vallance P, Harrison D. NO in the cardiovascular system. Cardiovascular Research. 43: 507-508. PMID 10690322 DOI: 10.1016/S0008-6363(99)00181-9  0.331
1999 Searles CD, Harrison DG. The interaction of nitric oxide, bradykinin, and the angiotensin II type 2 receptor: lessons learned from transgenic mice Journal of Clinical Investigation. 104: 1013-1014. PMID 10525037 DOI: 10.1172/Jci8507  0.403
1999 Gallis B, Corthals GL, Goodlett DR, Ueba H, Kim F, Presnell SR, Figeys D, Harrison DG, Berk BC, Aebersold R, Corson MA. Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002 Journal of Biological Chemistry. 274: 30101-30108. PMID 10514497 DOI: 10.1074/Jbc.274.42.30101  0.328
1999 Searles CD, Miwa Y, Harrison DG, Ramasamy S. Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase During Cell Growth Circulation Research. 85: 588-595. PMID 10506483 DOI: 10.1161/01.Res.85.7.588  0.35
1999 Griendling KK, Harrison DG. Dual role of reactive oxygen species in vascular growth. Circulation Research. 85: 562-3. PMID 10488060 DOI: 10.1161/01.Res.85.6.562  0.318
1999 Tummala PE, Chen XL, Sundell CL, Laursen JB, Hammes CP, Alexander RW, Harrison DG, Medford RM. Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: A potential link between the renin-angiotensin system and atherosclerosis. Circulation. 100: 1223-9. PMID 10484544 DOI: 10.1161/01.Cir.100.11.1223  0.357
1999 Münzel T, Hink U, Yigit H, Macharzina R, Harrison DG, Mülsch A. Role of superoxide dismutase in in vivo and in vitro nitrate tolerance. British Journal of Pharmacology. 127: 1224-1230. PMID 10455269 DOI: 10.1038/Sj.Bjp.0702622  0.346
1999 Kojda G, Laursen JB, Ramasamy S, Kent JD, Kurz S, Burchfield J, Shesely EG, Harrison DG. Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart rate control. Cardiovascular Research. 42: 206-13. PMID 10435012 DOI: 10.1016/S0008-6363(98)00315-0  0.37
1999 Münzel T, Harrison DG. Increased superoxide in heart failure: a biochemical baroreflex gone awry. Circulation. 100: 216-218. PMID 10411841 DOI: 10.1161/01.Cir.100.3.216  0.362
1999 Fukai T, Siegfried MR, Ushio-Fukai M, Griendling KK, Harrison DG. Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension. Circulation Research. 85: 23-8. PMID 10400907 DOI: 10.1161/01.Res.85.1.23  0.377
1999 Ramasamy S, Drummond GR, Ahn J, Storek M, Pohl J, Parthasarathy S, Harrison DG. Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells Molecular Pharmacology. 56: 116-123. PMID 10385691 DOI: 10.1124/Mol.56.1.116  0.393
1999 Kurz S, Hink U, Nickenig G, Borthayre AB, Harrison DG, Münzel T. Evidence for a Causal Role of the Renin-Angiotensin System in Nitrate Tolerance Circulation. 99: 3181-3187. PMID 10377083 DOI: 10.1161/01.Cir.99.24.3181  0.36
1999 Warnholtz A, Nickenig G, Schulz E, Macharzina R, Bräsen JH, Skatchkov M, Heitzer T, Stasch JP, Griendling KK, Harrison DG, Böhm M, Meinertz T, Münzel T. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation. 99: 2027-33. PMID 10209008 DOI: 10.1161/01.Cir.99.15.2027  0.351
1999 Skatchkov MP, Sperling D, Hink U, Mülsch A, Harrison DG, Sindermann I, Meinertz T, Münzel T. Validation of Lucigenin as a Chemiluminescent Probe to Monitor Vascular Superoxide as Well as Basal Vascular Nitric Oxide Production Biochemical and Biophysical Research Communications. 254: 319-324. PMID 9918836 DOI: 10.1006/Bbrc.1998.9942  0.326
1998 Zafari AM, Ushio-Fukai M, Akers M, Yin Q, Shah A, Harrison DG, Taylor WR, Griendling KK. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension (Dallas, Tex. : 1979). 32: 488-95. PMID 9740615 DOI: 10.1161/01.Hyp.32.3.488  0.373
1998 Vejlstrup NG, Bouloumie A, Boesgaard S, Andersen CB, Nielsen-Kudsk JE, Mortensen SA, Kent JD, Harrison DG, Busse R, Aldershvile J. Inducible nitric oxide synthase (iNOS) in the human heart: expression and localization in congestive heart failure. Journal of Molecular and Cellular Cardiology. 30: 1215-23. PMID 9689595 DOI: 10.1006/Jmcc.1998.0686  0.306
1998 Fukai T, Galis ZS, Meng XP, Parthasarathy S, Harrison DG. Vascular expression of extracellular superoxide dismutase in atherosclerosis. The Journal of Clinical Investigation. 101: 2101-11. PMID 9593766 DOI: 10.1172/Jci2105  0.328
1998 Inoue N, Ohara Y, Fukai T, Harrison DG, Nishida K. Probucol improves endothelial-dependent relaxation and decreases vascular superoxide production in cholesterol-fed rabbits. The American Journal of the Medical Sciences. 315: 242-7. PMID 9537638 DOI: 10.1097/00000441-199804000-00005  0.318
1998 Inoue N, Ohara Y, Fukai T, Harrison DG, Nishida K. Original ArticlesProbucol Improves Endothelial-Dependent Relaxation and Decreases Vascular Superoxide Production in Cholesterol-Fed Rabbits The American Journal of the Medical Sciences. 315. DOI: 10.1016/S0002-9629(15)40320-9  0.343
1997 Münzel T, Harrison DG. Evidence for a role of oxygen-derived free radicals and protein kinase C in nitrate tolerance Journal of Molecular Medicine. 75: 891-900. PMID 9428622 DOI: 10.1007/S001090050181  0.406
1997 Harrison DG. Cellular and molecular mechanisms of endothelial cell dysfunction. Journal of Clinical Investigation. 100: 2153-2157. PMID 9410891 DOI: 10.1172/Jci119751  0.342
1997 Wilcox JN, Subramanian RR, Sundell CL, Ross Tracey W, Pollock JS, Harrison DG, Marsden PA. Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2479-2488. PMID 9409218 DOI: 10.1161/01.Atv.17.11.2479  0.374
1997 Münzel T, Heitzer T, Harrison DG. The physiology and pathophysiology of the nitric oxide/superoxide system. Herz. 22: 158-172. PMID 9232165 DOI: 10.1007/Bf03044353  0.413
1997 Rajagopalan S, Laursen JB, Borthayre A, Kurz S, Keiser J, Haleen S, Giaid A, Harrison DG. Role for endothelin-1 in angiotensin II-mediated hypertension. Hypertension. 30: 29-34. PMID 9231817 DOI: 10.1161/01.Hyp.30.1.29  0.338
1997 Capers Q, Laursen JB, Fukui T, Rajagopalan S, Mori I, Lou P, Freeman BA, Berrington WR, Griendling KK, Harrison DG, Runge MS, Alexander RW, Taylor WR. Vascular thrombin receptor regulation in hypertensive rats. Circulation Research. 80: 838-44. PMID 9168786 DOI: 10.1161/01.Res.80.6.838  0.387
1997 Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG. Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation. 95: 588-93. PMID 9024144 DOI: 10.1161/01.Cir.95.3.588  0.386
1997 Laursen JB, Harrison DG. Modulation of myocardial oxygen consumption through ACE inhibitors. NO effect? Circulation. 95: 14-6. PMID 8994409 DOI: 10.1161/01.Cir.95.1.14  0.369
1997 Fukui T, Ishizaka N, Rajagopalan S, Laursen JB, Capers Q, Taylor WR, Harrison DG, de Leon H, Wilcox JN, Griendling KK. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circulation Research. 80: 45-51. PMID 8978321 DOI: 10.1161/01.Res.80.1.45  0.342
1997 HARRISON D. Role of oxidant mechanisms in hypertension American Journal of Hypertension. 10: 230A. DOI: 10.1016/S0895-7061(97)89495-2  0.358
1996 Harrison DG, Cai H. Endothelial control of vasomotion and nitric oxide production. Cardiology Clinics. 21: 289-302. PMID 14621446 DOI: 10.1016/S0733-8651(03)00073-0  0.383
1996 Harrison DG. ENDOTHELIAL CONTROL OF VASOMOTION AND NITRIC OXIDE PRODUCTION: A Potential Target for Risk Factor Management Cardiology Clinics. 14: 1-15. PMID 9072283 DOI: 10.1016/S0733-8651(05)70257-5  0.37
1996 Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. Journal of Clinical Investigation. 98: 2572-2579. PMID 8958220 DOI: 10.1172/Jci119076  0.356
1996 Harrison DG, Inoue N, Ohara Y, Fukai T. Modulation of endothelial cell nitric oxide synthase expression. Japanese Circulation Journal. 60: 815-21. PMID 8958189 DOI: 10.1253/Jcj.60.815  0.349
1996 Harrison DG, Sayegh H, Ohara Y, Inoue N, Venema RC. Regulation Of Expression Of The Endothelial Cell Nitric Oxide Synthase Clinical and Experimental Pharmacology and Physiology. 23: 251-255. PMID 8934617 DOI: 10.1111/J.1440-1681.1996.Tb02606.X  0.347
1996 Münzel T, Kurz S, Rajagopalan S, Thoenes M, Berrington WR, Thompson JA, Freeman BA, Harrison DG. Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase: A new action for an old drug Journal of Clinical Investigation. 98: 1465-1470. PMID 8823313 DOI: 10.1172/Jci118935  0.324
1996 Khan BV, Harrison DG, Olbrych MT, Alexander RW, Medford RM. Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 9114-9119. PMID 8799163 DOI: 10.1073/Pnas.93.17.9114  0.372
1996 Rajagopalan S, Harrison DG. Reversing endothelial dysfunction with ACE inhibitors: A new TREND? Circulation. 94: 240-243. PMID 8759059 DOI: 10.1161/01.Cir.94.3.240  0.408
1996 Münzel T, Kurz S, Heitzer T, Harrison DG. New insights into mechanisms underlying nitrate tolerance. American Journal of Cardiology. 77. PMID 8638523 DOI: 10.1016/S0002-9149(96)00185-3  0.402
1996 Venema RC, Sayegh HS, Kent JD, Harrison DG. Identification, Characterization, and Comparison of the Calmodulin-binding Domains of the Endothelial and Inducible Nitric Oxide Synthases Journal of Biological Chemistry. 271: 6435-6440. PMID 8626444 DOI: 10.1074/Jbc.271.11.6435  0.309
1996 Rajagopalan S, Kurz S, Münzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. The Journal of Clinical Investigation. 97: 1916-23. PMID 8621776 DOI: 10.1172/Jci118623  0.401
1995 Uematsu M, Ohara Y, Navas JP, Nishida K, Murphy TJ, Alexander RW, Nerem RM, Harrison DG. Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress. The American Journal of Physiology. 269: C1371-8. PMID 8572165 DOI: 10.1152/Ajpcell.1995.269.6.C1371  0.321
1995 Harrison DG, Ohara Y. Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: Implications for impaired vasomotion The American Journal of Cardiology. 75. PMID 7863980 DOI: 10.1016/0002-9149(95)80018-N  0.407
1995 Münzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. The Journal of Clinical Investigation. 95: 187-94. PMID 7814613 DOI: 10.1172/Jci117637  0.367
1995 Arnal J, Michel J, Harrison DG. Nitric oxide in the pathogenesis of hypertension. Current Opinion in Nephrology and Hypertension. 4: 182-188. PMID 7600050 DOI: 10.1097/00041552-199503000-00012  0.356
1995 Inoue N, Venema RC, Sayegh HS, Ohara Y, Murphy TJ, Harrison DG. Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-β1 Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1255-1261. PMID 7543000 DOI: 10.1161/01.Atv.15.8.1255  0.35
1995 Münzel T, Giaid A, Kurz S, Stewart DJ, Harrison DG. Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance. Proceedings of the National Academy of Sciences of the United States of America. 92: 5244-8. PMID 7539147 DOI: 10.1073/Pnas.92.11.5244  0.326
1995 Ohara Y, Sayegh HS, Yamin JJ, Harrison DG. Regulation of endothelial constitutive nitric oxide synthase by protein kinase C Hypertension. 25: 415-420. PMID 7533140 DOI: 10.1161/01.Hyp.25.3.415  0.359
1995 Anderson WD, Manoukian Sv, Zhang J, Peterson TE, Cipolla GD, Marshall JJ, King SB, Harrison DG, Wayne Alexander R, Treasure CB. 765-3 Superoxide Dismutase Reduces Superoxide Anion Levels in Balloon-injured Porcine Coronary Arteries Journal of the American College of Cardiology. 25: 276A. DOI: 10.1016/0735-1097(95)92603-3  0.312
1995 Johnston TS, Harrison DG, Klein JL, Anderson WD, Marshall JJ, Zhang J, Alexander RW, Treasure CB. 930-105 Xanthine-Oxidase Inhibition Improves Coronary Endothelium-Mediated Relaxation in Patients with Early Atherosclerosis Journal of the American College of Cardiology. 25: 115. DOI: 10.1016/0735-1097(95)91933-O  0.325
1995 Harrison DG. Alterations of vasomotor regulation in atherosclerosis Cardiovascular Drugs and Therapy. 9: 55-63. DOI: 10.1007/Bf00878573  0.402
1994 Harrison DG. Endothelial dysfunction in atherosclerosis Basic Research in Cardiology. 87-102. PMID 7945179 DOI: 10.1007/978-3-642-85660-0_8  0.413
1994 Arnal JF, Yamin J, Dockery S, Harrison DG. Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth American Journal of Physiology-Cell Physiology. 267. PMID 7526698 DOI: 10.1152/Ajpcell.1994.267.5.C1381  0.366
1994 Ohara Y, Peterson TE, Zheng B, Kuo JF, Harrison DG. Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 14: 1007-13. PMID 7515277 DOI: 10.1161/01.Atv.14.6.1007  0.301
1993 Kurz MA, Boyer TD, Whalen R, Peterson TE, Harrison DG. Nitroglycerin metabolism in vascular tissue: role of glutathione S-transferases and relationship between NO. and NO2- formation. The Biochemical Journal. 292: 545-50. PMID 8503888 DOI: 10.1042/Bj2920545  0.314
1993 Harrison DG, Bates JN. The nitrovasodilators. New ideas about old drugs. Circulation. 87: 1461-1467. PMID 8491000 DOI: 10.1161/01.Cir.87.5.1461  0.348
1993 Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. The Journal of Clinical Investigation. 91: 2546-51. PMID 8390482 DOI: 10.1172/Jci116491  0.326
1993 Nerem RM, Harrison DG, Taylor WR, Alexander RW. Hemodynamics and vascular endothelial biology Journal of Cardiovascular Pharmacology. 21. PMID 7681132 DOI: 10.1097/00005344-199321001-00002  0.351
1992 Fujii M, Nuno DW, Lamping KG, Dellsperger KC, Eastham CL, Harrison DG. Effect of hypertension and hypertrophy on coronary microvascular pressure. Circulation Research. 71: 120-126. PMID 1535028 DOI: 10.1161/01.Res.71.1.120  0.324
1992 Harrison DG, Kurz MA, Quillen JE, Sellke FW, Mügge A. Normal and pathophysiologic considerations of endothelial regulation of vascular tone and their relevance to nitrate therapy American Journal of Cardiology. 70. PMID 1529921 DOI: 10.1016/0002-9149(92)90589-Q  0.396
1992 Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. The Journal of Clinical Investigation. 90: 2092-6. PMID 1385480 DOI: 10.1172/Jci116092  0.357
1992 Myers PR, Guerra R, Harrison DG. Release of multiple endothelium-derived relaxing factors from porcine coronary arteries. Journal of Cardiovascular Pharmacology. 20: 392-400. PMID 1279283 DOI: 10.1097/00005344-199209000-00008  0.329
1991 Harrison DG. Endothelial modulation of vascular tone: relevance to coronary angioplasty and restenosis. Journal of the American College of Cardiology. 17: 71-76. PMID 2016485 DOI: 10.1016/0735-1097(91)90941-2  0.377
1991 Bates JN, Harrison DG, Myers PR, Minor RL. EDRF: nitrosylated compound or authentic nitric oxide. Basic Research in Cardiology. 86: 17-26. PMID 1953608 DOI: 10.1007/978-3-642-72461-9_3  0.319
1991 Mügge A, Elwell JH, Peterson TE, Hofmeyer TG, Heistad DD, Harrison DG. Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits. Circulation Research. 69: 1293-1300. PMID 1934359 DOI: 10.1161/01.Res.69.5.1293  0.376
1991 Mügge A, Harrison DG. L-Arginine Does Not Restore Endothelial Dysfunction in Atherosclerotic Rabbit Aorta in vitro Journal of Vascular Research. 28: 354-357. PMID 1912602 DOI: 10.1159/000158881  0.362
1991 Harrison DG, Treasure CB, Mügge A, Dellsperger KC, Lamping KG. Hypertension and the coronary circulation. With special attention to endothelial regulation. American Journal of Hypertension. 4. PMID 1910638 DOI: 10.1093/Ajh/4.7.454S  0.402
1991 Mugge A, Elwell JH, Peterson TE, Harrison DG. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity American Journal of Physiology-Cell Physiology. 260. PMID 1847583 DOI: 10.1152/Ajpcell.1991.260.2.C219  0.394
1991 Tomanek RJ, Wessel TJ, Harrison DG. Capillary growth and geometry during long-term hypertension and myocardial hypertrophy in dogs American Journal of Physiology - Heart and Circulatory Physiology. 261. PMID 1833986 DOI: 10.1152/Ajpheart.1991.261.4.H1011  0.302
1991 Bates JN, Baker MT, Guerra R, Harrison DG. Nitric oxide generation from nitroprusside by vascular tissue. Evidence that reduction of the nitroprusside anion and cyanide loss are required. Biochemical Pharmacology. 42: 157-165. PMID 1768273 DOI: 10.1016/0006-2952(91)90406-U  0.321
1991 Myers PR, Banitt PF, Guerra R, Harrison DG. Role of the endothelium in modulation of the acetylcholine vasoconstrictor response in porcine coronary microvessels. Cardiovascular Research. 25: 129-137. PMID 1742764 DOI: 10.1093/Cvr/25.2.129  0.31
1991 Mügge A, Peterson T, Harrison DG. Release of nitrogen oxides from cultured bovine aortic endothelial cells is not impaired by calcium channel antagonists. Circulation. 83: 1404-1409. PMID 1707354 DOI: 10.1161/01.Cir.83.4.1404  0.33
1991 Murphy S, Minor RL, Welk G, Harrison DG. Central nervous system astroglial cells release nitrogen oxide(s) with vasorelaxant properties Journal of Cardiovascular Pharmacology. 17. DOI: 10.1097/00005344-199100001-00047  0.305
1991 Mügge A, Elwell JH, Heistad DD, Harrison DG. Treatment with superoxide dismutase improves vascular responses in atherosclerotic rabbits Journal of the American College of Cardiology. 17. DOI: 10.1016/0735-1097(91)91200-X  0.325
1990 Minor RL, Myers PR, Guerra R, Bates JN, Harrison DG. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. The Journal of Clinical Investigation. 86: 2109-16. PMID 2254462 DOI: 10.1172/Jci114949  0.372
1990 Cappelli-Bigazzi M, Lamping KG, Nuno DW, Harrison DG. Leukocyte and platelet-derived factors augment canine coronary constriction to serotonin. American Journal of Physiology-Heart and Circulatory Physiology. 259. PMID 2171364 DOI: 10.1152/Ajpheart.1990.259.4.H1161  0.334
1990 Murphy S, Minor RL, Welk G, Harrison DG. Evidence for an astrocyte-derived vasorelaxing factor with properties similar to nitric oxide Journal of Neurochemistry. 55: 349-351. PMID 2113082 DOI: 10.1111/J.1471-4159.1990.Tb08860.X  0.331
1990 Sellke FW, Quillen JE, Brooks LA, Harrison DG. Endothelial modulation of the coronary vasculature in vessels perfused via mature collaterals. Circulation. 81: 1938-1947. PMID 2111743 DOI: 10.1161/01.Cir.81.6.1938  0.338
1990 Myers PR, Minor RL, Guerra R, Bates JN, Harrison DG. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide. Nature. 345: 161-3. PMID 2110626 DOI: 10.1038/345161A0  0.338
1990 Sellke FW, Armstrong ML, Harrison DG. Endothelium-dependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates. Circulation. 81: 1586-1593. PMID 2110036 DOI: 10.1161/01.Cir.81.5.1586  0.356
1990 Sellke FW, Myers PR, Bates JN, Harrison DG. Influence of vessel size on the sensitivity of porcine coronary microvessels to nitroglycerin. American Journal of Physiology-Heart and Circulatory Physiology. 258. PMID 2106798 DOI: 10.1152/Ajpheart.1990.258.2.H515  0.305
1989 Myers PR, Banitt PF, Guerra R, Harrison DG. Characteristics of canine coronary resistance arteries: importance of endothelium. American Journal of Physiology-Heart and Circulatory Physiology. 257. PMID 2788367 DOI: 10.1152/Ajpheart.1989.257.2.H603  0.324
1989 Myers PR, Guerra R, Harrison DG. Release of NO and EDRF from cultured bovine aortic endothelial cells. American Journal of Physiology-Heart and Circulatory Physiology. 256. PMID 2784944 DOI: 10.1152/Ajpheart.1989.256.4.H1030  0.356
1989 Harrison DG. From isolated vessels to the catheterization laboratory. Studies of endothelial function in the coronary circulation of humans. Circulation. 80: 703-706. PMID 2670317 DOI: 10.1161/01.Cir.80.3.703  0.31
1989 Guerra R, Brotherton AFA, Goodwin PJ, Clark CR, Armstrong ML, Harrison DG. Mechanisms of Abnormal Endothelium-Dependent Vascular Relaxation in Atherosclerosis: Implications for Altered Autocrine and Paracrine Functions of EDRF Journal of Vascular Research. 26: 300-314. PMID 2576820 DOI: 10.1159/000158779  0.359
1989 Lopez JAG, Armstrong ML, Harrison DG, Piegors DJ, Heistad DD. Vascular responses to leukocyte products in atherosclerotic primates. Circulation Research. 65: 1078-1086. PMID 2507195 DOI: 10.1161/01.Res.65.4.1078  0.333
1989 Tomanek RJ, Schalk KA, Marcus ML, Harrison DG. Coronary angiogenesis during long-term hypertension and left ventricular hypertrophy in dogs. Circulation Research. 65: 352-9. PMID 2473855 DOI: 10.1161/01.Res.65.2.352  0.321
1988 Lopez JAG, Armstrong ML, Harrison DG, Piegors DJ, Heistad DD. Responsiveness of iliac collateral vessels to constrictor stimuli in atherosclerotic primates. Circulation Research. 63: 1020-1028. PMID 3197270 DOI: 10.1161/01.Res.63.6.1020  0.334
1987 Heistad DD, Harrison DG, Armstrong ML, Piegors D, Breese K, Meegan M. Serotonin and experimental vascular disease. International Journal of Cardiology. 14: 205-212. PMID 3818136 DOI: 10.1016/0167-5273(87)90009-X  0.327
1987 Harrison DG, Armstrong ML, Freiman PC, Heistad DD. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. Journal of Clinical Investigation. 80: 1808-1811. PMID 3680531 DOI: 10.1172/Jci113276  0.348
1987 Harrison DG, Freiman PC, Armstrong ML, Marcus ML, Heistad DD. Alterations of vascular reactivity in atherosclerosis. Circulation Research. 61. DOI: 10.1161/01.Res.61.5_Suppl.Ii-74  0.382
1986 Freiman PC, Mitchell GG, Heistad DD, Armstrong ML, Harrison DG. Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates. Circulation Research. 58: 783-789. PMID 3087655 DOI: 10.1161/01.Res.58.6.783  0.366
1986 Chilian WM, Harrison DG, Haws CW, Snyder WD, Marcus ML. Adrenergic coronary tone during submaximal exercise in the dog is produced by circulating catecholamines. Evidence for adrenergic denervation supersensitivity in the myocardium but not in coronary vessels. Circulation Research. 58: 68-82. PMID 3002658 DOI: 10.1161/01.Res.58.1.68  0.5
1986 Harrison DG, Chilian WM, Marcus ML. Absence of functioning alpha-adrenergic receptors in mature canine coronary collaterals. Circulation Research. 59: 133-42. PMID 2874899 DOI: 10.1161/01.Res.59.2.133  0.544
1985 Harrison DG, Barnes DH, Hiratzka LF, Eastham CL, Kerber RE, Marcus ML. The effect of cardiac hypertrophy on the coronary collateral circulation. Circulation. 71: 1135-45. PMID 3158452 DOI: 10.1161/01.Cir.71.6.1135  0.301
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