Year |
Citation |
Score |
2024 |
Gui C, Kalkreuter E, Lauterbach L, Yang D, Shen B. Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate. Nature Chemical Biology. PMID 38831037 DOI: 10.1038/s41589-024-01636-y |
0.59 |
|
2024 |
Steele AD, Jiang H, Pan G, Lim SK, Kalkreuter E, Kwong T, Ju J, Rajski S, Shen B. Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis. Biochemistry. PMID 38345531 DOI: 10.1021/acs.biochem.3c00672 |
0.652 |
|
2024 |
Fluegel LL, Deng MR, Su P, Kalkreuter E, Yang D, Rudolf JD, Dong LB, Shen B. Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology. PMID 38262768 DOI: 10.1093/jimb/kuae003 |
0.677 |
|
2023 |
Kalkreuter E, Kautsar SA, Yang D, Teijaro CN, Bader CD, Fluegel LL, Davis CM, Simpson JR, Steele AD, Gui C, Meng S, Li G, Viehrig K, Ye F, Su P, et al. The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity. Biorxiv : the Preprint Server For Biology. PMID 38168313 DOI: 10.1101/2023.12.14.571759 |
0.512 |
|
2023 |
Gui C, Kalkreuter E, Liu YC, Li G, Steele AD, Yang D, Chang C, Shen B. Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nature Chemical Biology. PMID 37945897 DOI: 10.1038/s41589-023-01476-2 |
0.514 |
|
2023 |
Bhardwaj M, Cui Z, Daniel Hankore E, Moonschi FH, Saghaeiannejad Esfahani H, Kalkreuter E, Gui C, Yang D, Phillips GN, Thorson JS, Shen B, Van Lanen SG. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220468120. PMID 36802426 DOI: 10.1073/pnas.2220468120 |
0.672 |
|
2022 |
Gui C, Kalkreuter E, Liu YC, Adhikari A, Teijaro CN, Yang D, Chang C, Shen B. Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. Journal of the American Chemical Society. 144: 20452-20462. PMID 36279548 DOI: 10.1021/jacs.2c08957 |
0.532 |
|
2021 |
Kalkreuter E, Shen B. MIO-containing aminomutases for α- to β-amino acids. Trends in Chemistry. 4: 91-92. PMID 36304426 DOI: 10.1016/j.trechm.2021.09.007 |
0.36 |
|
2021 |
Meng S, Steele AD, Yan W, Pan G, Kalkreuter E, Liu YC, Xu Z, Shen B. Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase. Nature Communications. 12: 5672. PMID 34584078 DOI: 10.1038/s41467-021-25798-8 |
0.669 |
|
2021 |
Kalkreuter E, Bingham KS, Keeler AM, Lowell AN, Schmidt JJ, Sherman DH, Williams GJ. Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase. Nature Communications. 12: 2193. PMID 33850151 DOI: 10.1038/s41467-021-22497-2 |
0.574 |
|
2021 |
Cao M, Zheng C, Yang D, Kalkreuter E, Adhikari A, Liu YC, Rateb ME, Shen B. Cryptic sulfur incorporation in thioangucycline biosynthesis. Angewandte Chemie (International Ed. in English). PMID 33465268 DOI: 10.1002/anie.202015570 |
0.539 |
|
2020 |
Zheng CJ, Kalkreuter E, Fan BY, Liu YC, Dong LB, Shen B. PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine -Acetyltransferases. Acs Chemical Biology. PMID 33314918 DOI: 10.1021/acschembio.0c00773 |
0.573 |
|
2019 |
Kalkreuter E, Pan G, Cepeda AJ, Shen B. Targeting Bacterial Genomes for Natural Product Discovery. Trends in Pharmacological Sciences. PMID 31822352 DOI: 10.1016/J.Tips.2019.11.002 |
0.672 |
|
2019 |
Dong LB, Liu YC, Cepeda AJ, Kalkreuter E, Deng MR, Rudolf JD, Chang C, Joachimiak A, Phillips GN, Shen B. Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 31291107 DOI: 10.1021/jacs.9b06183 |
0.672 |
|
2019 |
Kalkreuter E, Keeler AM, Malico AA, Bingham KS, Gayen AK, Williams GJ. Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli. Acs Synthetic Biology. PMID 31134799 DOI: 10.1021/acssynbio.9b00078 |
0.58 |
|
2019 |
Dong LB, Zhang X, Shen B, Rudolf JD, Deng MR, Kalkreuter E, Cepeda AJ, Renata H. Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 30735041 DOI: 10.1021/Jacs.8B13452 |
0.655 |
|
2019 |
Kalkreuter E, CroweTipton JM, Lowell AN, Sherman DH, Williams GJ. Engineering the Substrate Specificity of a Modular Polyketide Synthase for Installation of Consecutive Non-Natural Extender Units. Journal of the American Chemical Society. PMID 30676722 DOI: 10.1021/Jacs.8B10521 |
0.569 |
|
2018 |
Kalkreuter E, Williams GJ. Engineering enzymatic assembly lines for the production of new antimicrobials. Current Opinion in Microbiology. 45: 140-148. PMID 29733997 DOI: 10.1016/j.mib.2018.04.005 |
0.604 |
|
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