Edward Kalkreuter - Publications

Affiliations: 
Florida State University, Tallahassee, FL, United States 
Area:
Natural product discovery, natural product biosynthesis, natural product engineering

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gui C, Kalkreuter E, Lauterbach L, Yang D, Shen B. Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate. Nature Chemical Biology. PMID 38831037 DOI: 10.1038/s41589-024-01636-y  0.59
2024 Steele AD, Jiang H, Pan G, Lim SK, Kalkreuter E, Kwong T, Ju J, Rajski S, Shen B. Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis. Biochemistry. PMID 38345531 DOI: 10.1021/acs.biochem.3c00672  0.652
2024 Fluegel LL, Deng MR, Su P, Kalkreuter E, Yang D, Rudolf JD, Dong LB, Shen B. Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology. PMID 38262768 DOI: 10.1093/jimb/kuae003  0.677
2023 Kalkreuter E, Kautsar SA, Yang D, Teijaro CN, Bader CD, Fluegel LL, Davis CM, Simpson JR, Steele AD, Gui C, Meng S, Li G, Viehrig K, Ye F, Su P, et al. The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity. Biorxiv : the Preprint Server For Biology. PMID 38168313 DOI: 10.1101/2023.12.14.571759  0.512
2023 Gui C, Kalkreuter E, Liu YC, Li G, Steele AD, Yang D, Chang C, Shen B. Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nature Chemical Biology. PMID 37945897 DOI: 10.1038/s41589-023-01476-2  0.514
2023 Bhardwaj M, Cui Z, Daniel Hankore E, Moonschi FH, Saghaeiannejad Esfahani H, Kalkreuter E, Gui C, Yang D, Phillips GN, Thorson JS, Shen B, Van Lanen SG. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220468120. PMID 36802426 DOI: 10.1073/pnas.2220468120  0.672
2022 Gui C, Kalkreuter E, Liu YC, Adhikari A, Teijaro CN, Yang D, Chang C, Shen B. Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. Journal of the American Chemical Society. 144: 20452-20462. PMID 36279548 DOI: 10.1021/jacs.2c08957  0.532
2021 Kalkreuter E, Shen B. MIO-containing aminomutases for α- to β-amino acids. Trends in Chemistry. 4: 91-92. PMID 36304426 DOI: 10.1016/j.trechm.2021.09.007  0.36
2021 Meng S, Steele AD, Yan W, Pan G, Kalkreuter E, Liu YC, Xu Z, Shen B. Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase. Nature Communications. 12: 5672. PMID 34584078 DOI: 10.1038/s41467-021-25798-8  0.669
2021 Kalkreuter E, Bingham KS, Keeler AM, Lowell AN, Schmidt JJ, Sherman DH, Williams GJ. Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase. Nature Communications. 12: 2193. PMID 33850151 DOI: 10.1038/s41467-021-22497-2  0.574
2021 Cao M, Zheng C, Yang D, Kalkreuter E, Adhikari A, Liu YC, Rateb ME, Shen B. Cryptic sulfur incorporation in thioangucycline biosynthesis. Angewandte Chemie (International Ed. in English). PMID 33465268 DOI: 10.1002/anie.202015570  0.539
2020 Zheng CJ, Kalkreuter E, Fan BY, Liu YC, Dong LB, Shen B. PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine -Acetyltransferases. Acs Chemical Biology. PMID 33314918 DOI: 10.1021/acschembio.0c00773  0.573
2019 Kalkreuter E, Pan G, Cepeda AJ, Shen B. Targeting Bacterial Genomes for Natural Product Discovery. Trends in Pharmacological Sciences. PMID 31822352 DOI: 10.1016/J.Tips.2019.11.002  0.672
2019 Dong LB, Liu YC, Cepeda AJ, Kalkreuter E, Deng MR, Rudolf JD, Chang C, Joachimiak A, Phillips GN, Shen B. Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 31291107 DOI: 10.1021/jacs.9b06183  0.672
2019 Kalkreuter E, Keeler AM, Malico AA, Bingham KS, Gayen AK, Williams GJ. Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli. Acs Synthetic Biology. PMID 31134799 DOI: 10.1021/acssynbio.9b00078  0.58
2019 Dong LB, Zhang X, Shen B, Rudolf JD, Deng MR, Kalkreuter E, Cepeda AJ, Renata H. Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 30735041 DOI: 10.1021/Jacs.8B13452  0.655
2019 Kalkreuter E, CroweTipton JM, Lowell AN, Sherman DH, Williams GJ. Engineering the Substrate Specificity of a Modular Polyketide Synthase for Installation of Consecutive Non-Natural Extender Units. Journal of the American Chemical Society. PMID 30676722 DOI: 10.1021/Jacs.8B10521  0.569
2018 Kalkreuter E, Williams GJ. Engineering enzymatic assembly lines for the production of new antimicrobials. Current Opinion in Microbiology. 45: 140-148. PMID 29733997 DOI: 10.1016/j.mib.2018.04.005  0.604
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