Jon S. Thorson - Publications

Affiliations: 
Pharmacy University of Kentucky, Lexington, KY 

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Voss SR, Ponomareva LV, Dwaraka VB, Pardue KE, Baddar NWAH, Rodgers AK, Woodcock MR, Qiu Q, Crowner A, Blichmann D, Khatri S, Thorson JS. HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration. Scientific Reports. 9: 6751. PMID 31043677 DOI: 10.1038/s41598-019-43230-6  0.76
2019 Fatima A, Aftab U, Shaaban KA, Thorson JS, Sajid I. Spore forming Actinobacterial diversity of Cholistan Desert Pakistan: Polyphasic taxonomy, antimicrobial potential and chemical profiling. Bmc Microbiology. 19: 49. PMID 30795744 DOI: 10.1186/s12866-019-1414-x  0.6
2019 Savi DC, Shaaban KA, Mitra P, Ponomareva LV, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by the citrus phytopathogen Phyllosticta citricarpa. The Journal of Antibiotics. PMID 30792517 DOI: 10.1038/s41429-019-0154-3  0.76
2019 Biecker AL, Liu X, Thorson JS, Yang Z, Van Lanen SG. Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics. Molecules (Basel, Switzerland). 24. PMID 30691073 DOI: 10.3390/molecules24030433  0.6
2018 Ye Q, Zhang Y, Cao Y, Wang X, Guo Y, Chen J, Horn J, Ponomareva LV, Chaiswing L, Shaaban KA, Wei Q, Anderson BD, St Clair DK, Zhu H, Leggas M, ... Thorson JS, et al. Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell Chemical Biology. PMID 30661989 DOI: 10.1016/j.chembiol.2018.11.013  0.76
2018 Savi DC, Shaaban KA, Gos FMW, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by Microbacterium sp. LGMB471 with antifungal activity against the phytopathogen Phyllosticta citricarpa. Folia Microbiologica. PMID 30565048 DOI: 10.1007/s12223-018-00668-x  0.6
2018 Abbas M, Elshahawi SI, Wang X, Ponomareva LV, Sajid I, Shaaban KA, Thorson JS. Puromycins B-E, Naturally Occurring Amino-Nucleosides Produced by the Himalayan Isolate Streptomyces sp. PU-14G. Journal of Natural Products. PMID 30418763 DOI: 10.1021/acs.jnatprod.8b00720  0.76
2018 Cui Z, Liu X, Overbay J, Cai W, Wang X, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of Organic Chemistry. PMID 29768920 DOI: 10.1021/acs.joc.8b00855  0.6
2018 Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG. Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy. PMID 29735559 DOI: 10.1128/AAC.00193-18  0.64
2018 Cui Z, Wang X, Koppermann S, Thorson JS, Ducho C, Van Lanen SG. Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. Journal of Natural Products. PMID 29553733 DOI: 10.1021/acs.jnatprod.7b01054  0.6
2018 de Medeiros AG, Savi DC, Mitra P, Shaaban KA, Jha AK, Thorson JS, Rohr J, Glienke C. Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds. Folia Microbiologica. PMID 29497981 DOI: 10.1007/s12223-018-0587-2  0.6
2018 Savi DC, Shaaban KA, Gos FMWR, Ponomareva LV, Thorson JS, Glienke C, Rohr J. Phaeophleospora vochysiae Savi & Glienke sp. nov. Isolated from Vochysia divergens Found in the Pantanal, Brazil, Produces Bioactive Secondary Metabolites. Scientific Reports. 8: 3122. PMID 29449610 DOI: 10.1038/s41598-018-21400-2  0.76
2018 Koppermann S, Cui Z, Fischer PD, Wang X, Ludwig J, Thorson JS, Van Lanen SG, Ducho C. Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics. Chemmedchem. PMID 29438582 DOI: 10.1002/cmdc.201700793  0.6
2017 Gos FMWR, Savi DC, Shaaban KA, Thorson JS, Aluizio R, Possiede YM, Rohr J, Glienke C. Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil). Frontiers in Microbiology. 8: 1642. PMID 28932210 DOI: 10.3389/fmicb.2017.01642  0.6
2017 Wang X, Elshahawi SI, Cai W, Zhang Y, Ponomareva LV, Chen X, Copley GC, Hower JC, Zhan CG, Parkin S, Rohr J, Van Lanen SG, Shaaban KA, Thorson JS. Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2. Journal of Natural Products. PMID 28358212 DOI: 10.1021/acs.jnatprod.7b00108  0.76
2017 Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN, Thorson JS, Singh S. Structure and specificity of a permissive bacterial C-prenyltransferase. Nature Chemical Biology. PMID 28166207 DOI: 10.1038/nchembio.2285  1
2017 Wang X, Zhang Y, Ponomareva LV, Qiu Q, Woodcock R, Elshahawi SI, Chen X, Zhou Z, Hatcher BE, Hower JC, Zhan CG, Parkin S, Kharel MK, Voss SR, Shaaban KA, ... Thorson JS, et al. Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe. Angewandte Chemie (International Ed. in English). PMID 28140487 DOI: 10.1002/anie.201612447  0.76
2017 Hughes RR, Shaaban KA, Zhang J, Cao H, Phillips GN, Thorson JS. OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation. Chembiochem : a European Journal of Chemical Biology. PMID 28067448 DOI: 10.1002/cbic.201600676  0.92
2016 Zhang J, Hughes RR, Saunders MA, Elshahawi SI, Ponomareva LV, Zhang Y, Winchester SR, Scott SA, Sunkara M, Morris AJ, Prendergast MA, Shaaban KA, Thorson JS. Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. Journal of Natural Products. PMID 28029796 DOI: 10.1021/acs.jnatprod.6b00949  0.92
2016 Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, ... Thorson JS, et al. Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. Journal of Natural Products. PMID 28029795 DOI: 10.1021/acs.jnatprod.6b00948  0.92
2016 Cai W, Wang X, Elshahawi SI, Ponomareva LV, Liu X, McErlean MR, Cui Z, Arlinghaus AL, Thorson JS, Van Lanen SG. Antibacterial and Cytotoxic Actinomycins Y6-Y9 and Zp from Streptomyces sp. Strain Gö-GS12. Journal of Natural Products. PMID 27736087 DOI: 10.1021/acs.jnatprod.6b00742  0.76
2016 Huber TD, Johnson BR, Zhang J, Thorson JS. AdoMet analog synthesis and utilization: current state of the art. Current Opinion in Biotechnology. 42: 189-197. PMID 27506965 DOI: 10.1016/j.copbio.2016.07.005  1
2016 Marshall DJ, Harried SS, Murphy JL, Hall CA, Shekhani MS, Pain C, Lyons CA, Chillemi A, Malavasi F, Pearce HL, Thorson JS, Prudent JR. Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27434591 DOI: 10.1038/mt.2016.119  0.48
2016 Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet isosteres resistant to classical AdoMet degradation pathways. Acs Chemical Biology. PMID 27351335 DOI: 10.1021/acschembio.6b00348  1
2016 Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Structural Dynamics (Melville, N.Y.). 3: 034702. PMID 27191010 DOI: 10.1063/1.4948539  0.44
2016 Han L, Singh S, Thorson JS, Phillips GN. Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis. Structural Dynamics (Melville, N.Y.). 3: 012004. PMID 26958582 DOI: 10.1063/1.4941368  0.44
2015 Zhang J, Ponomareva LV, Nandurkar NS, Yuan Y, Fang L, Zhan CG, Thorson JS. Influence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer Activity. Acs Medicinal Chemistry Letters. 6: 1053-8. PMID 26487911 DOI: 10.1021/acsmedchemlett.5b00120  0.92
2015 Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, ... Thorson JS, et al. Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8". Organic Letters. PMID 26458135 DOI: 10.1021/acs.orglett.5b02788  0.76
2015 Peltier-Pain P, Singh S, Thorson JS. Characterization of early enzymes involved in TDP-aminodideoxypentose biosynthesis en route to indolocarbazole AT2433. Chembiochem : a European Journal of Chemical Biology. PMID 26289554 DOI: 10.1002/cbic.201500365  1
2015 Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. The Journal of Biological Chemistry. PMID 26240141 DOI: 10.1074/jbc.M115.673459  1
2015 Zhang Y, Ye Q, Wang X, She QB, Thorson JS. A Divergent Enantioselective Strategy for the Synthesis of Griseusins. Angewandte Chemie (International Ed. in English). PMID 26230189 DOI: 10.1002/anie.201505022  1
2015 Ponomareva LV, Athippozhy A, Thorson JS, Voss SR. Using Ambystoma mexicanum (Mexican axolotl) embryos, chemical genetics, and microarray analysis to identify signaling pathways associated with tissue regeneration. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 178: 128-35. PMID 26092703 DOI: 10.1016/j.cbpc.2015.06.004  1
2015 Shaaban KA, Elshahawi SI, Wang X, Horn J, Kharel MK, Leggas M, Thorson JS. Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691. Journal of Natural Products. 78: 1723-9. PMID 26091285 DOI: 10.1021/acs.jnatprod.5b00429  1
2015 Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins. 83: 1547-54. PMID 26061967 DOI: 10.1002/prot.24844  1
2015 Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chemical Biology. PMID 26023720 DOI: 10.1021/acschembio.5b00244  1
2015 Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, ... Thorson JS, et al. Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Organic Letters. 17: 2796-9. PMID 25961722 DOI: 10.1021/acs.orglett.5b01203  1
2015 Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/jbc.M115.646414  1
2015 Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS. A comprehensive review of glycosylated bacterial natural products. Chemical Society Reviews. 44: 7591-697. PMID 25735878 DOI: 10.1039/c4cs00426d  1
2015 Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2. Angewandte Chemie (International Ed. in English). 54: 2811-5. PMID 25581707 DOI: 10.1002/anie.201409792  0.64
2015 Savi DC, Shaaban KA, Vargas N, Ponomareva LV, Possiede YM, Thorson JS, Glienke C, Rohr J. Microbispora sp. LGMB259 endophytic actinomycete isolated from Vochysia divergens (Pantanal, Brazil) producing β-carbolines and indoles with biological activity. Current Microbiology. 70: 345-54. PMID 25385358 DOI: 10.1007/s00284-014-0724-3  0.76
2015 Zhang J, Ponomareva LV, Nandurkar NS, Yuan Y, Fang L, Zhan CG, Thorson JS. Influence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer Activity Acs Medicinal Chemistry Letters. 6: 1053-1058. DOI: 10.1021/acsmedchemlett.5b00120  1
2015 Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2 Angewandte Chemie - International Edition. 54: 2811-2815. DOI: 10.1002/anie.201409792  1
2014 Nandurkar NS, Zhang J, Ye Q, Ponomareva LV, She QB, Thorson JS. The identification of perillyl alcohol glycosides with improved antiproliferative activity. Journal of Medicinal Chemistry. 57: 7478-84. PMID 25121720 DOI: 10.1021/jm500870u  1
2014 Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, ... ... Thorson JS, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/cb500327m  1
2014 Goff RD, Thorson JS. Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads. Medchemcomm. 5: 1036-1047. PMID 25071927 DOI: 10.1039/C4MD00117F  1
2014 Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization. Acs Nano. 8: 8104-12. PMID 25025628 DOI: 10.1021/nn502181k  1
2014 Singh S, Nandurkar NS, Thorson JS. Characterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6. Chembiochem : a European Journal of Chemical Biology. 15: 1418-21. PMID 24978950 DOI: 10.1002/cbic.201402119  1
2014 Singh S, Peltier-Pain P, Tonelli M, Thorson JS. A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways. Organic Letters. 16: 3220-3. PMID 24911465 DOI: 10.1021/ol501241a  1
2014 Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46. The Journal of Antibiotics. 67: 571-5. PMID 24713874 DOI: 10.1038/ja.2014.37  1
2014 Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem : a European Journal of Chemical Biology. 15: 647-52. PMID 24677528 DOI: 10.1002/cbic.201300779  1
2014 Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. The Febs Journal. 281: 4224-39. PMID 24649856 DOI: 10.1111/febs.12784  1
2014 Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/anie.201308272  1
2014 Wang X, Elshahawi SI, Shaaban KA, Fang L, Ponomareva LV, Zhang Y, Copley GC, Hower JC, Zhan CG, Kharel MK, Thorson JS. Ruthmycin, a new tetracyclic polyketide from Streptomyces sp. RM-4-15. Organic Letters. 16: 456-9. PMID 24341358 DOI: 10.1021/ol4033418  1
2014 Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2. The Journal of Antibiotics. 67: 223-30. PMID 24252813 DOI: 10.1038/ja.2013.113  1
2014 Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Natural Product Research. 28: 337-9. PMID 24237421 DOI: 10.1080/14786419.2013.855932  1
2014 Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization Acs Nano. 8: 8104-8112. DOI: 10.1021/nn502181k  1
2013 Zhang Y, Wang X, Sunkara M, Ye Q, Ponomereva LV, She QB, Morris AJ, Thorson JS. A diastereoselective oxa-Pictet-Spengler-based strategy for (+)-frenolicin B and epi-(+)-frenolicin B synthesis. Organic Letters. 15: 5566-9. PMID 24151973 DOI: 10.1021/ol4027649  1
2013 Zhang J, Ponomareva LV, Marchillo K, Zhou M, Andes DR, Thorson JS. Synthesis and antibacterial activity of doxycycline neoglycosides. Journal of Natural Products. 76: 1627-36. PMID 23987662 DOI: 10.1021/np4003096  1
2013 Shaaban KA, Wang X, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. Journal of Natural Products. 76: 1619-26. PMID 23947794 DOI: 10.1021/np400308w  1
2013 Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Zhang Y, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. Journal of Natural Products. 76: 1441-7. PMID 23944931 DOI: 10.1021/np400231r  1
2013 Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. Acs Chemical Biology. 8: 1632-9. PMID 23662776 DOI: 10.1021/cb400068k  1
2013 Gantt RW, Peltier-Pain P, Singh S, Zhou M, Thorson JS. Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 7648-53. PMID 23610417 DOI: 10.1073/pnas.1220220110  1
2013 Wang F, Zhou M, Singh S, Yennamalli RM, Bingman CA, Thorson JS, Phillips GN. Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins. 81: 1277-82. PMID 23526584 DOI: 10.1002/prot.24289  1
2013 Zhou M, Hamza A, Zhan CG, Thorson JS. Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors. Journal of Natural Products. 76: 279-86. PMID 23360118 DOI: 10.1021/np300890h  1
2012 Zhou M, Hou Y, Hamza A, Pain C, Zhan CG, Bugni TS, Thorson JS. Probing the regiospecificity of enzyme-catalyzed steroid glycosylation. Organic Letters. 14: 5424-7. PMID 23075289 DOI: 10.1021/ol3024924  1
2012 Gantt RW, Thorson JS. High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer. Methods in Enzymology. 516: 345-60. PMID 23034237 DOI: 10.1016/B978-0-12-394291-3.00009-5  1
2012 Peltier-Pain P, Marchillo K, Zhou M, Andes DR, Thorson JS. Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation. Organic Letters. 14: 5086-9. PMID 22984807 DOI: 10.1021/ol3023374  1
2012 Singh S, Phillips GN, Thorson JS. The structural biology of enzymes involved in natural product glycosylation. Natural Product Reports. 29: 1201-37. PMID 22688446 DOI: 10.1039/c2np20039b  1
2012 Goff RD, Thorson JS. Enhancement of cyclopamine via conjugation with nonmetabolic sugars. Organic Letters. 14: 2454-7. PMID 22540932 DOI: 10.1021/ol300703z  1
2012 Shen B, Thorson JS. Expanding nature's chemical repertoire through metabolic engineering and biocatalysis. Current Opinion in Chemical Biology. 16: 99-100. PMID 22464247 DOI: 10.1016/j.cbpa.2012.03.006  1
2011 Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN. Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proceedings of the National Academy of Sciences of the United States of America. 108: 17649-54. PMID 21987796 DOI: 10.1073/pnas.1108484108  1
2011 Gantt RW, Peltier-Pain P, Thorson JS. Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules. Natural Product Reports. 28: 1811-53. PMID 21901218 DOI: 10.1039/c1np00045d  1
2011 Gantt RW, Peltier-Pain P, Cournoyer WJ, Thorson JS. Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions. Nature Chemical Biology. 7: 685-91. PMID 21857660 DOI: 10.1038/nchembio.638  1
2011 Lee HS, Thorson JS. Development of a universal glycosyltransferase assay amenable to high-throughput formats. Analytical Biochemistry. 418: 85-8. PMID 21741952 DOI: 10.1016/j.ab.2011.06.016  1
2011 Peltier-Pain P, Timmons SC, Grandemange A, Benoit E, Thorson JS. Warfarin glycosylation invokes a switch from anticoagulant to anticancer activity. Chemmedchem. 6: 1347-50. PMID 21714096 DOI: 10.1002/cmdc.201100178  1
2011 Chang A, Singh S, Phillips GN, Thorson JS. Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation. Current Opinion in Biotechnology. 22: 800-8. PMID 21592771 DOI: 10.1016/j.copbio.2011.04.013  1
2011 Singh S, Chang A, Goff RD, Bingman CA, Grüschow S, Sherman DH, Phillips GN, Thorson JS. Structural characterization of the mitomycin 7-O-methyltransferase. Proteins. 79: 2181-8. PMID 21538548 DOI: 10.1002/prot.23040  1
2011 Zhou M, Thorson JS. Asymmetric enzymatic glycosylation of mitoxantrone. Organic Letters. 13: 2786-8. PMID 21528870 DOI: 10.1021/ol200977u  1
2011 Goff RD, Singh S, Thorson JS. Glycosyloxyamine neoglycosylation: a model study using calicheamicin. Chemmedchem. 6: 774-6. PMID 21520418 DOI: 10.1002/cmdc.201100028  1
2011 Chang A, Singh S, Bingman CA, Thorson JS, Phillips GN. Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 67: 197-203. PMID 21358050 DOI: 10.1107/S090744491100360X  1
2011 Moretti R, Chang A, Peltier-Pain P, Bingman CA, Phillips GN, Thorson JS. Expanding the nucleotide and sugar 1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution. The Journal of Biological Chemistry. 286: 13235-43. PMID 21317292 DOI: 10.1074/jbc.M110.206433  1
2011 Williams GJ, Yang J, Zhang C, Thorson JS. Recombinant E. coli prototype strains for in vivo glycorandomization. Acs Chemical Biology. 6: 95-100. PMID 20886903 DOI: 10.1021/cb100267k  1
2010 Goff RD, Thorson JS. Assessment of chemoselective neoglycosylation methods using chlorambucil as a model. Journal of Medicinal Chemistry. 53: 8129-39. PMID 20973561 DOI: 10.1021/jm101024j  1
2010 Horsman GP, Chen Y, Thorson JS, Shen B. Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes. Proceedings of the National Academy of Sciences of the United States of America. 107: 11331-5. PMID 20534556 DOI: 10.1073/pnas.1003442107  1
2009 Goff RD, Thorson JS. Enhancing the divergent activities of betulinic acid via neoglycosylation. Organic Letters. 11: 461-4. PMID 19102682 DOI: 10.1021/ol8025704  1
2009 McCoy JG, Johnson HD, Singh S, Bingman CA, Lei IK, Thorson JS, Phillips GN. Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins. 74: 50-60. PMID 18561189 DOI: 10.1002/prot.22131  1
2008 Johnson HD, Thorson JS. Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formation. Journal of the American Chemical Society. 130: 17662-3. PMID 19055330 DOI: 10.1021/ja807557a  1
2008 Gantt RW, Goff RD, Williams GJ, Thorson JS. Probing the aglycon promiscuity of an engineered glycosyltransferase. Angewandte Chemie (International Ed. in English). 47: 8889-92. PMID 18924204 DOI: 10.1002/anie.200803508  1
2008 Zhang C, Moretti R, Jiang J, Thorson JS. The in vitro characterization of polyene glycosyltransferases AmphDI and NysDI. Chembiochem : a European Journal of Chemical Biology. 9: 2506-14. PMID 18798210 DOI: 10.1002/cbic.200800349  1
2008 Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN, Thorson JS. Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chemistry & Biology. 15: 842-53. PMID 18721755 DOI: 10.1016/j.chembiol.2008.06.011  1
2008 Williams GJ, Gantt RW, Thorson JS. The impact of enzyme engineering upon natural product glycodiversification. Current Opinion in Chemical Biology. 12: 556-64. PMID 18678278 DOI: 10.1016/j.cbpa.2008.07.013  1
2008 Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS. Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. The Journal of Biological Chemistry. 283: 22628-36. PMID 18502766 DOI: 10.1074/jbc.M800503200  1
2008 Timmons SC, Thorson JS. Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria. Current Opinion in Chemical Biology. 12: 297-305. PMID 18424273 DOI: 10.1016/j.cbpa.2008.03.017  1
2008 Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ. Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly. Acs Chemical Biology. 3: 220-9. PMID 18422304 DOI: 10.1021/cb700258r  1
2008 Williams GJ, Goff RD, Zhang C, Thorson JS. Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chemistry & Biology. 15: 393-401. PMID 18420146 DOI: 10.1016/j.chembiol.2008.02.017  1
2008 Moretti R, Thorson JS. A comparison of sugar indicators enables a universal high-throughput sugar-1-phosphate nucleotidyltransferase assay. Analytical Biochemistry. 377: 251-8. PMID 18387352 DOI: 10.1016/j.ab.2008.03.018  1
2008 Gao Q, Thorson JS. The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. Fems Microbiology Letters. 282: 105-14. PMID 18328078 DOI: 10.1111/j.1574-6968.2008.01112.x  1
2008 Williams GJ, Thorson JS. A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution. Nature Protocols. 3: 357-62. PMID 18323806 DOI: 10.1038/nprot.2007.538  1
2008 Bitto E, Huang Y, Bingman CA, Singh S, Thorson JS, Phillips GN. The structure of flavin-dependent tryptophan 7-halogenase RebH. Proteins. 70: 289-93. PMID 17876823 DOI: 10.1002/prot.21627  1
2007 Williams GJ, Zhang C, Thorson JS. Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nature Chemical Biology. 3: 657-62. PMID 17828251 DOI: 10.1038/nchembio.2007.28  1
2007 Griffith BR, Krepel C, Fu X, Blanchard S, Ahmed A, Edmiston CE, Thorson JS. Model for antibiotic optimization via neoglycosylation: synthesis of liponeoglycopeptides active against VRE. Journal of the American Chemical Society. 129: 8150-5. PMID 17564440 DOI: 10.1021/ja068602r  1
2007 Hui JP, Yang J, Thorson JS, Soo EC. Selective detection of sugar phosphates by capillary electrophoresis/mass spectrometry and its application to an engineered E. coli host. Chembiochem : a European Journal of Chemical Biology. 8: 1180-8. PMID 17562551 DOI: 10.1002/cbic.200700116  1
2007 Moretti R, Thorson JS. Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA. The Journal of Biological Chemistry. 282: 16942-7. PMID 17434871 DOI: 10.1074/jbc.M701951200  1
2007 Zhang C, Fu Q, Albermann C, Li L, Thorson JS. The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification. Chembiochem : a European Journal of Chemical Biology. 8: 385-90. PMID 17262863 DOI: 10.1002/cbic.200600509  1
2006 Zhang C, Albermann C, Fu X, Thorson JS. The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility. Journal of the American Chemical Society. 128: 16420-1. PMID 17177349 DOI: 10.1021/ja065950k  1
2006 Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, Markley JL, Thorson JS. Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chemical Biology. 1: 451-60. PMID 17168523 DOI: 10.1021/cb6002898  1
2006 Griffith BR, Thorson JS. A sweet success for substrate engineering. Nature Chemical Biology. 2: 659-60. PMID 17108980 DOI: 10.1038/nchembio1206-659  1
2006 Ahmed A, Peters NR, Fitzgerald MK, Watson JA, Hoffmann FM, Thorson JS. Colchicine glycorandomization influences cytotoxicity and mechanism of action. Journal of the American Chemical Society. 128: 14224-5. PMID 17076473 DOI: 10.1021/ja064686s  1
2006 Zhang C, Griffith BR, Fu Q, Albermann C, Fu X, Lee IK, Li L, Thorson JS. Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science (New York, N.Y.). 313: 1291-4. PMID 16946071 DOI: 10.1126/science.1130028  1
2006 Gao Q, Zhang C, Blanchard S, Thorson JS. Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chemistry & Biology. 13: 733-43. PMID 16873021 DOI: 10.1016/j.chembiol.2006.05.009  1
2006 Biggins JB, Prudent JR, Marshall DJ, Thorson JS. A continuous assay for DNA cleavage using molecular break lights. Methods in Molecular Biology (Clifton, N.J.). 335: 83-92. PMID 16785622 DOI: 10.1385/1-59745-069-3:83  1
2006 Blanchard S, Thorson JS. Enzymatic tools for engineering natural product glycosylation. Current Opinion in Chemical Biology. 10: 263-71. PMID 16675288 DOI: 10.1016/j.cbpa.2006.04.001  1
2006 Zhang C, Albermann C, Fu X, Peters NR, Chisholm JD, Zhang G, Gilbert EJ, Wang PG, Van Vranken DL, Thorson JS. RebG- and RebM-catalyzed indolocarbazole diversification. Chembiochem : a European Journal of Chemical Biology. 7: 795-804. PMID 16575939 DOI: 10.1002/cbic.200500504  1
2006 Borisova SA, Zhang C, Takahashi H, Zhang H, Wong AW, Thorson JS, Liu HW. Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angewandte Chemie (International Ed. in English). 45: 2748-53. PMID 16538696 DOI: 10.1002/anie.200503195  1
2006 Zhang C, Weller RL, Thorson JS, Rajski SR. Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. Journal of the American Chemical Society. 128: 2760-1. PMID 16506729 DOI: 10.1021/ja056231t  1
2005 Bililign T, Griffith BR, Thorson JS. Structure, activity, synthesis and biosynthesis of aryl-C-glycosides. Natural Product Reports. 22: 742-60. PMID 16311633 DOI: 10.1039/b407364a  1
2005 Langenhan JM, Griffith BR, Thorson JS. Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification. Journal of Natural Products. 68: 1696-711. PMID 16309329 DOI: 10.1021/np0502084  1
2005 Griffith BR, Langenhan JM, Thorson JS. 'Sweetening' natural products via glycorandomization. Current Opinion in Biotechnology. 16: 622-30. PMID 16226456 DOI: 10.1016/j.copbio.2005.10.002  1
2005 Langenhan JM, Peters NR, Guzei IA, Hoffmann FM, Thorson JS. Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. Proceedings of the National Academy of Sciences of the United States of America. 102: 12305-10. PMID 16105948 DOI: 10.1073/pnas.0503270102  1
2005 Yang J, Fu X, Liao J, Liu L, Thorson JS. Structure-based engineering of E. coli galactokinase as a first step toward in vivo glycorandomization. Chemistry & Biology. 12: 657-64. PMID 15975511 DOI: 10.1016/j.chembiol.2005.04.009  1
2005 Fu X, Albermann C, Zhang C, Thorson JS. Diversifying vancomycin via chemoenzymatic strategies. Organic Letters. 7: 1513-5. PMID 15816740 DOI: 10.1021/ol0501626  1
2005 Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Antitumor antibiotics: bleomycin, enediynes, and mitomycin. Chemical Reviews. 105: 739-58. PMID 15700963 DOI: 10.1021/cr030117g  1
2005 Langenhan JM, Thorson JS. Recent carbohydrate-based chemoselective ligation applications Current Organic Synthesis. 2: 59-81. DOI: 10.2174/1570179052996937  1
2004 Fu X, Langenhan JM, Thorson JS. Combinatorial chemoenzymatic strategies for in vitro glycorandomization: Efforts toward antibiotic optimization. Discovery Medicine. 4: 111-4. PMID 20705004  1
2004 Bililign T, Hyun CG, Williams JS, Czisny AM, Thorson JS. The hedamycin locus implicates a novel aromatic PKS priming mechanism. Chemistry & Biology. 11: 959-69. PMID 15271354 DOI: 10.1016/j.chembiol.2004.04.016  1
2004 Yang J, Liu L, Thorson JS. Structure-based enhancement of the first anomeric glucokinase. Chembiochem : a European Journal of Chemical Biology. 5: 992-6. PMID 15239058 DOI: 10.1002/cbic.200400041  1
2004 Hoffmeister D, Thorson JS. Mechanistic implications of Escherichia coli galactokinase structure-based engineering. Chembiochem : a European Journal of Chemical Biology. 5: 989-92. PMID 15239057 DOI: 10.1002/cbic.200400003  1
2004 Dürr C, Hoffmeister D, Wohlert SE, Ichinose K, Weber M, Von Mulert U, Thorson JS, Bechthold A. The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers. Angewandte Chemie (International Ed. in English). 43: 2962-5. PMID 15170316 DOI: 10.1002/anie.200453758  1
2004 Yang J, Hoffmeister D, Liu L, Fu X, Thorson JS. Natural product glycorandomization. Bioorganic & Medicinal Chemistry. 12: 1577-84. PMID 15112655 DOI: 10.1016/j.bmc.2003.12.046  1
2004 Thorson JS, Barton WA, Hoffmeister D, Albermann C, Nikolov DB. Structure-based enzyme engineering and its impact on in vitro glycorandomization. Chembiochem : a European Journal of Chemical Biology. 5: 16-25. PMID 14695508 DOI: 10.1002/cbic.200300620  1
2003 Hoffmeister D, Yang J, Liu L, Thorson JS. Creation of the first anomeric D/L-sugar kinase by means of directed evolution. Proceedings of the National Academy of Sciences of the United States of America. 100: 13184-9. PMID 14612558 DOI: 10.1073/pnas.2235011100  1
2003 Fu X, Albermann C, Jiang J, Liao J, Zhang C, Thorson JS. Antibiotic optimization via in vitro glycorandomization. Nature Biotechnology. 21: 1467-9. PMID 14608364 DOI: 10.1038/nbt909  1
2003 Liu W, Ahlert J, Gao Q, Wendt-Pienkowski E, Shen B, Thorson JS. Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model. Proceedings of the National Academy of Sciences of the United States of America. 100: 11959-63. PMID 14528002 DOI: 10.1073/pnas.2034291100  1
2003 Biggins JB, Onwueme KC, Thorson JS. Resistance to enediyne antitumor antibiotics by CalC self-sacrifice. Science (New York, N.Y.). 301: 1537-41. PMID 12970566 DOI: 10.1126/science.1086695  1
2003 Yang J, Fu X, Jia Q, Shen J, Biggins JB, Jiang J, Zhao J, Schmidt JJ, Wang PG, Thorson JS. Studies on the substrate specificity of Escherichia coli galactokinase. Organic Letters. 5: 2223-6. PMID 12816414 DOI: 10.1021/ol034642d  1
2003 Jiang J, Albermann C, Thorson JS. Application of the nucleotidylyltransferase Ep toward the chemoenzymatic synthesis of dTDP-desosamine analogues. Chembiochem : a European Journal of Chemical Biology. 4: 443-6. PMID 12740816 DOI: 10.1002/cbic.200200566  1
2003 Albermann C, Soriano A, Jiang J, Vollmer H, Biggins JB, Barton WA, Lesniak J, Nikolov DB, Thorson JS. Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization. Organic Letters. 5: 933-6. PMID 12633109 DOI: 10.1021/ol0341086  1
2003 Zazopoulos E, Huang K, Staffa A, Liu W, Bachmann BO, Nonaka K, Ahlert J, Thorson JS, Shen B, Farnet CM. A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nature Biotechnology. 21: 187-90. PMID 12536216 DOI: 10.1038/nbt784  1
2003 Hyun CG, Bililign T, Liao J, Thorson JS. The biosynthesis of indolocarbazoles in a heterologous E. coli host. Chembiochem : a European Journal of Chemical Biology. 4: 114-7. PMID 12512086 DOI: 10.1002/cbic.200390004  1
2002 Losey HC, Jiang J, Biggins JB, Oberthür M, Ye XY, Dong SD, Kahne D, Thorson JS, Walsh CT. Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chemistry & Biology. 9: 1305-14. PMID 12498883 DOI: 10.1016/S1074-5521(02)00270-3  1
2002 Bililign T, Shepard EM, Ahlert J, Thorson JS. On the origin of deoxypentoses: evidence to support a glucose progenitor in the biosynthesis of calicheamicin. Chembiochem : a European Journal of Chemical Biology. 3: 1143-6. PMID 12404643 DOI: 10.1002/1439-7633(20021104)3:11<1143::AID-CBIC1143>3.0.CO;2-W  1
2002 Barton WA, Biggins JB, Jiang J, Thorson JS, Nikolov DB. Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proceedings of the National Academy of Sciences of the United States of America. 99: 13397-402. PMID 12374866 DOI: 10.1073/pnas.192468299  1
2002 Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS. The calicheamicin gene cluster and its iterative type I enediyne PKS. Science (New York, N.Y.). 297: 1173-6. PMID 12183629 DOI: 10.1126/science.1072105  1
2001 Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 29712364 DOI: 10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K  1
2001 Barton WA, Lesniak J, Biggins JB, Jeffrey PD, Jiang J, Rajashankar KR, Thorson JS, Nikolov DB. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nature Structural Biology. 8: 545-51. PMID 11373625 DOI: 10.1038/88618  1
2001 Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives This contribution was supported by the National Institutes of Health (GM58196 and CA84374), a Cancer Center Support Grant (CA-08748), and a grant from the Special Projects Committee of the Society of Memorial Sloan-Kettering Cancer Center. J.S.T. is an Alfred P. Sloan Research Fellow and a Rita Allen Foundation Scholar. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 11317315 DOI: 10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K  1
2001 Thorson JS. Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites Current Organic Chemistry. 5: 139-167. DOI: 10.2174/1385272013375706  1
2000 Thorson JS, Sievers EL, Ahlert J, Shepard E, Whitwam RE, Onwueme KC, Ruppen M. Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research. Current Pharmaceutical Design. 6: 1841-79. PMID 11102565  1
2000 Biggins JB, Prudent JR, Marshall DJ, Ruppen M, Thorson JS. A continuous assay for DNA cleavage: The application of 'break lights' to enediynes, iron-dependent and nucleases Proceedings of the National Academy of Sciences of the United States of America. 97: 13537-13542. PMID 11095715 DOI: 10.1073/pnas.240460997  1
2000 Whitwam RE, Ahlert J, Holman TR, Ruppen M, Thorson JS. The gene calC encodes for a non-heme iron metalloprotein responsible for calicheamicin self-resistance in Micromonospora [9] Journal of the American Chemical Society. 122: 1556-1557. DOI: 10.1021/ja993612w  1
2000 Jiang J, Biggins JB, Thorson JS. A general enzymatic method for the synthesis of natural and 'unnatural' UDP- and TDP-nucleotide sugars [20] Journal of the American Chemical Society. 122: 6803-6804. DOI: 10.1021/ja001444y  1
1999 Zhao Y, Thorson JS. Chemoenzymatic synthesis of the Salmonella group E1 core trisaccharide using a recombinant β-(1→4)-mannosyltransferase Carbohydrate Research. 319: 184-191. PMID 10520265 DOI: 10.1016/S0008-6215(99)00116-0  1
1999 Zhao L, Ahlert J, Xue Y, Thorson JS, Sherman DH, Liu HW. Engineering a methymycin/pikromycin-calicheamicin hybrid: Construction of two new macrolides carrying a designed sugar moiety [6] Journal of the American Chemical Society. 121: 9881-9882. DOI: 10.1021/ja992810k  1
1999 Thorson JS, Shen B, Whitwam RE, Liu W, Li Y, Ahlert J. Enediyne biosynthesis and self-resistance: A progress report Bioorganic Chemistry. 27: 172-188. DOI: 10.1006/bioo.1998.1122  1
1998 Zhao Y, Thorson JS. A Methodological Comparison: The Advantage of Phosphorimidates in Expanding the Sugar Nucleotide Repertoire. The Journal of Organic Chemistry. 63: 7568-7572. PMID 11672420  1
1998 Thorson JS, Cornish VW, Barrett JE, Cload ST, Yano T, Schultz PG. A biosynthetic approach for the incorporation of unnatural amino acids into proteins. Methods in Molecular Biology (Clifton, N.J.). 77: 43-73. PMID 9770661 DOI: 10.1385/0-89603-397-X:43  1
1998 Zhao Y, Biggins JB, Thorson JS. Acceptor specificity of Salmonella GDP-Man:αLRha1→3αDGal-PP-Und β1→4-mannosyltransferase: A simplified assay based on unnatural acceptors [16] Journal of the American Chemical Society. 120: 12986-12987. DOI: 10.1021/ja982285+  1
1998 Thorson JS, Shin I, Chapman E, Stenberg G, Mannervik B, Schultz PG. Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis Journal of the American Chemical Society. 120: 451-452. DOI: 10.1021/ja9731682  1
1997 Chapman E, Thorson JS, Schultz PG. Mutational analysis of backbone hydrogen bonds in staphylococcal nuclease [2] Journal of the American Chemical Society. 119: 7151-7152. DOI: 10.1021/ja970826+  1
1996 He X, Thorson JS, Liu HW. Probing the coenzyme and substrate binding events of CDP-D-glucose 4,6-dehydratase: mechanistic implications. Biochemistry. 35: 4721-31. PMID 8664262 DOI: 10.1021/bi952706p  1
1995 Thorson JS, Chapman E, Schultz PG. Analysis of hydrogen bonding strengths in proteins using unnatural amino acids Journal of the American Chemical Society. 117: 9361-9362. DOI: 10.1021/ja00141a032  1
1995 Thorson JS, Chapman E, Murphy EC, Schultz PG, Judice JK. Linear free energy analysis of hydrogen bonding in proteins Journal of the American Chemical Society. 117: 1157-1158.  1
1994 Lo SF, Miller VP, Lei Y, Thorson JS, Liu HW, Schottel JL. CDP-6-deoxy-delta 3,4-glucoseen reductase from Yersinia pseudotuberculosis: enzyme purification and characterization of the cloned gene. Journal of Bacteriology. 176: 460-8. PMID 8288541  1
1994 Thorson JS, Kelly TM, Liu HW. Cloning, sequencing, and overexpression in Escherichia coli of the alpha-D-glucose-1-phosphate cytidylyltransferase gene isolated from Yersinia pseudotuberculosis. Journal of Bacteriology. 176: 1840-9. PMID 8144449  1
1994 Thorson JS, Lo SF, Ploux O, He X, Liu HW. Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA. Journal of Bacteriology. 176: 5483-93. PMID 8071227  1
1994 Liu HW, Thorson JS. Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria. Annual Review of Microbiology. 48: 223-56. PMID 7826006 DOI: 10.1146/annurev.mi.48.100194.001255  1
1993 Miller VP, Thorson JS, Ploux O, Lo SF, Liu HW. Cofactor characterization and mechanistic studies of CDP-6-deoxy-delta 3,4-glucoseen reductase: exploration into a novel enzymatic C-O bond cleavage event. Biochemistry. 32: 11934-42. PMID 8218267  0.96
1993 Thorson JS, Liu HW. Coenzyme B6 as a redox cofactor: A new role for an old coenzyme? Journal of the American Chemical Society. 115: 12177-12178.  1
1993 Thorson JS, Liu HW. Characterization of the first PMP-dependent iron-sulfur-containing enzyme which is essential for the biosynthesis of 3,6-dideoxyhexoses Journal of the American Chemical Society. 115: 7539-7540.  1
1993 Thorson JS, Lo SF, Liu HW. Molecular basis of 3,6-dideoxyhexose biosynthesis elucidation of CDP-ascarylose biosynthetic genes and their relationship to other 3,6-dideoxyhexose pathways Journal of the American Chemical Society. 115: 5827-5828.  1
1993 Thorson JS, Lo SF, Liu HW, Richard Hutchinson C. Biosynthesis of 3,6-dideoxyhexoses: New mechanistic reflections upon 2,6-dideoxy, 4,6-dideoxy, and amino sugar construction Journal of the American Chemical Society. 115: 6999-7000.  1
1992 Yu Y, Russell RN, Thorson JS, Liu LD, Liu HW. Mechanistic studies of the biosynthesis of 3,6-dideoxyhexoses in Yersinia pseudotuberculosis. Purification and stereochemical analysis of CDP-D-glucose oxidoreductase. The Journal of Biological Chemistry. 267: 5868-75. PMID 1556102  1
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