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Le Cong - Publications

Affiliations: 
2014 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
 2017 Biology, Bioengineering, McGovern Institute Massachusetts Institute of Technology, Cambridge, MA, United States 
 2017 Zhang Lab, Regev Lab Broad Institute (MIT/Harvard) 
 2018- Pathology, Genetics, Wu Tsai Neuroscience Institute Stanford University, Palo Alto, CA 
Website:
https://profiles.stanford.edu/186687
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick C, Wang J, Hughes NW, Donosa O, Andrejka L, Karmakar S, Aboiralor I, Cong L, Sage J, Petrov DA, Winslow MM. Modeling the genomic complexity of human cancer using Cas12a mice. Biorxiv : the Preprint Server For Biology. PMID 38496463 DOI: 10.1101/2024.03.07.583774  0.305
2023 Wang X, Xu G, Johnson WA, Qu Y, Yin D, Ramkissoon N, Xiang H, Cong L. Long sequence insertion via CRISPR/Cas gene-editing with transposase, recombinase, and integrase. Current Opinion in Biomedical Engineering. 28. PMID 38549686 DOI: 10.1016/j.cobme.2023.100491  0.323
2022 Wang C, Xia Q, Zhang Q, Qu Y, Su S, Cheng JKW, Hughes NW, Cong L. CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells. Frontiers in Cell and Developmental Biology. 9: 719705. PMID 35774104 DOI: 10.3389/fcell.2021.719705  0.394
2022 Wang C, Qu Y, Cheng JKW, Hughes NW, Zhang Q, Wang M, Cong L. dCas9-based gene editing for cleavage-free genomic knock-in of long sequences. Nature Cell Biology. 24: 268-278. PMID 35145221 DOI: 10.1038/s41556-021-00836-1  0.4
2021 Wang C, Cheng JKW, Zhang Q, Hughes NW, Xia Q, Winslow MM, Cong L. Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects. Nucleic Acids Research. PMID 33619540 DOI: 10.1093/nar/gkaa1264  0.411
2019 Nidetz NF, McGee MC, Tse LV, Li C, Cong L, Li Y, Huang W. Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery. Pharmacology & Therapeutics. 107453. PMID 31836454 DOI: 10.1016/J.Pharmthera.2019.107453  0.302
2019 Luan B, Xu G, Feng M, Cong L, Zhou R. Combined Computational-Experimental Approach to Explore Molecular Mechanism of SaCas9 with Broadened DNA Targeting Range. Journal of the American Chemical Society. PMID 30924644 DOI: 10.1021/Jacs.8B13144  0.353
2017 Cleary B, Cong L, Cheung A, Lander ES, Regev A. Efficient Generation of Transcriptomic Profiles by Random Composite Measurements. Cell. PMID 29153835 DOI: 10.1016/J.Cell.2017.10.023  0.315
2017 Cong L. CRISPR: Groundbreaking technology for RNA-guided genome engineering. Analytical Biochemistry. PMID 28479380 DOI: 10.1016/j.ab.2017.05.005  0.326
2017 Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JY, Nevin J, Herbst RH, Yanai I, et al. Abstract A10: A distinct gene module for T cell dysfunction uncoupled from T cell activation and controlled by metallothioneins Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A10  0.333
2016 Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JY, Nevin J, Herbst RH, Yanai I, et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 166: 1500-1511.e9. PMID 27610572 DOI: 10.1016/J.Cell.2016.08.052  0.364
2016 Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science (New York, N.Y.). 351: 407-11. PMID 26721686 DOI: 10.1126/Science.Aad5177  0.587
2016 Cong L, Singer M, Wang C, Kwon J, Anderson A, Rozenblatt-Rosen O, Kuchroo V, Regev A. Abstract B085: Combining transcriptomic profiling and genome engineering to dissect regulation of tumor immunology Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B085  0.359
2015 Spencer NY, Yan Z, Cong L, Zhang Y, Engelhardt JF, Stanton RC. Definitive Localization of Intracellular Proteins: Novel Approach Using CRISPR-Cas9 Genome Editing, with Glucose 6-Phosphate Dehydrogenase as a Model. Analytical Biochemistry. PMID 26576833 DOI: 10.1016/J.Ab.2015.11.002  0.341
2015 Nishimasu H, Cong L, Yan WX, Ran FA, Zetsche B, Li Y, Kurabayashi A, Ishitani R, Zhang F, Nureki O. Crystal Structure of Staphylococcus aureus Cas9. Cell. 162: 1113-26. PMID 26317473 DOI: 10.1016/J.Cell.2015.08.007  0.488
2015 Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Sequence determinants of improved CRISPR sgRNA design. Genome Research. PMID 26063738 DOI: 10.1101/Gr.191452.115  0.521
2015 Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/Nature14299  0.588
2015 Cong L, Zhang F. Genome engineering using CRISPR-Cas9 system. Methods in Molecular Biology (Clifton, N.J.). 1239: 197-217. PMID 25408407 DOI: 10.1007/978-1-4939-1862-1_10  0.553
2014 Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. Genome Biology. 15: 554. PMID 25476604 DOI: 10.1186/S13059-014-0554-4  0.507
2013 Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/Nature12466  0.688
2013 Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.). 339: 819-23. PMID 23287718 DOI: 10.1126/Science.1231143  0.528
2013 Wu J, Wang Z, Shi Z, Zhang S, Ming R, Zhu S, Khan MA, Tao S, Korban SS, Wang H, Chen NJ, Nishio T, Xu X, Cong L, Qi K, et al. The genome of the pear (Pyrus bretschneideri Rehd.). Genome Research. 23: 396-408. PMID 23149293 DOI: 10.1101/Gr.144311.112  0.323
2012 Cong L, Zhou R, Kuo YC, Cunniff M, Zhang F. Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nature Communications. 3: 968. PMID 22828628 DOI: 10.1038/Ncomms1962  0.578
2012 Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Genome-scale promoter engineering by coselection MAGE. Nature Methods. 9: 591-3. PMID 22484848 DOI: 10.1038/Nmeth.1971  0.682
2012 Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F. A transcription activator-like effector toolbox for genome engineering. Nature Protocols. 7: 171-92. PMID 22222791 DOI: 10.1038/Nprot.2011.431  0.586
2011 Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/Nbt.1775  0.69
2009 Xu Y, Cong L, Chen C, Wei L, Zhao Q, Xu X, Ma Y, Bartlam M, Rao Z. Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain. Journal of Virology. 83: 1083-92. PMID 18987156 DOI: 10.1128/Jvi.01862-08  0.304
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