| Year |
Citation |
Score |
| 2024 |
Lin CH, Chin Y, Zhou M, Sobol RW, Hung MC, Tan M. Protein lipoylation: mitochondria, cuproptosis, and beyond. Trends in Biochemical Sciences. PMID 38714376 DOI: 10.1016/j.tibs.2024.04.002 |
0.392 |
|
| 2024 |
Fu J, Ling J, Li CF, Tsai CL, Yin W, Hou J, Chen P, Cao Y, Kang Y, Sun Y, Xia X, Jiang Z, Furukawa K, Lu Y, Wu M, ... ... Hung MC, et al. Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer. Nature Communications. 15: 3149. PMID 38605037 DOI: 10.1038/s41467-024-47242-3 |
0.332 |
|
| 2024 |
Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, ... ... Hung MC, et al. BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers. Cancer Discovery. PMID 38552003 DOI: 10.1158/2159-8290.CD-23-1220 |
0.369 |
|
| 2024 |
Jabbarzadeh Kaboli P, Chen HF, Babaeizad A, Roustai Geraylow K, Yamaguchi H, Hung MC. Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer. Cancer Letters. 588: 216780. PMID 38462033 DOI: 10.1016/j.canlet.2024.216780 |
0.329 |
|
| 2024 |
Liu C, Zhou C, Xia W, Zhou Y, Qiu Y, Weng J, Zhou Q, Chen W, Wang YN, Lee HH, Wang SC, Kuang M, Yu D, Ren N, Hung MC. Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma. Nature Communications. 15: 1009. PMID 38307859 DOI: 10.1038/s41467-024-45215-0 |
0.563 |
|
| 2024 |
Yamaguchi H, Chang LC, Chang OS, Chen YF, Hsiao YC, Wu CS, Hung MC. MRCK as a Potential Target for Claudin-Low Subtype of Breast Cancer. International Journal of Biological Sciences. 20: 1-14. PMID 38164185 DOI: 10.7150/ijbs.88285 |
0.384 |
|
| 2023 |
Wang S, Chang CW, Huang J, Zeng S, Zhang X, Hung MC, Hou J. Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models. The Journal of Clinical Investigation. PMID 37883181 DOI: 10.1172/JCI166841 |
0.347 |
|
| 2023 |
Sun X, Wang WJ, Lang J, Yang R, Shen WJ, Sun L, Hsu JM, Chan LC, Li CW, Xia W, Ke B, Yao G, Huang K, Lee PC, Koller PB, ... Hung MC, et al. Inhibition of Galectin-9 sensitizes tumors to anthracycline treatment via inducing antitumor immunity. International Journal of Biological Sciences. 19: 4644-4656. PMID 37781042 DOI: 10.7150/ijbs.84108 |
0.351 |
|
| 2023 |
Wang YN, Lee HH, Jiang Z, Chan LC, Hortobagyi GN, Yu D, Hung MC. Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation. International Journal of Biological Sciences. 19: 2957-2973. PMID 37416781 DOI: 10.7150/ijbs.84592 |
0.592 |
|
| 2023 |
Zhang Y, Zhao Z, Huang LA, Liu Y, Yao J, Sun C, Li Y, Zhang Z, Ye Y, Yuan F, Nguyen TK, Garlapati NR, Wu A, Egranov SD, Caudle AS, ... ... Hung MC, et al. Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation. Cell Metabolism. PMID 37329887 DOI: 10.1016/j.cmet.2023.05.009 |
0.486 |
|
| 2023 |
Cho J, Min HY, Lee HJ, Hyun SY, Sim JY, Noh M, Hwang SJ, Park SH, Boo HJ, Lee HJ, Hong S, Park RW, Shin YK, Hung MC, Lee HY. RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. The Journal of Clinical Investigation. 133. PMID 37183821 DOI: 10.1172/JCI171901 |
0.315 |
|
| 2023 |
Wang HC, Chang WC, Lee DY, Li XG, Hung MC. IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth. American Journal of Cancer Research. 13: 1067-1081. PMID 37034222 |
0.343 |
|
| 2023 |
Xu A, Liu M, Huang MF, Zhang Y, Hu R, Gingold JA, Liu Y, Zhu D, Chien CS, Wang WC, Liao Z, Yuan F, Hsu CW, Tu J, Yu Y, ... ... Hung MC, et al. Rewired mA epitranscriptomic networks link mutant p53 to neoplastic transformation. Nature Communications. 14: 1694. PMID 36973285 DOI: 10.1038/s41467-023-37398-9 |
0.74 |
|
| 2023 |
Sun C, Ye Y, Tan Z, Liu Y, Li Y, Hu W, Liang K, Egranov SD, Huang LA, Zhang Z, Zhang Y, Yao J, Nguyen TK, Zhao Z, Wu A, ... ... Hung MC, et al. Tumor-associated nonmyelinating Schwann cell-expressed promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science Advances. 9: eadd6995. PMID 36724291 DOI: 10.1126/sciadv.add6995 |
0.584 |
|
| 2023 |
Lin ZS, Chung CC, Liu YC, Chang CH, Liu HC, Liang YY, Huang TL, Chen TM, Lee CH, Tang CH, Hung MC, Chen YH. EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression. Elife. 12. PMID 36622753 DOI: 10.7554/eLife.79432 |
0.312 |
|
| 2022 |
Wang SH, Chou WC, Huang HC, Lee TA, Hsiao TC, Wang LH, Huang KB, Kuo CT, Chao CH, Chang SJ, Hsu JM, Weng J, Ren N, Li FA, Lai YJ, ... ... Hung MC, et al. Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis. American Journal of Cancer Research. 12: 4721-4736. PMID 36381324 |
0.309 |
|
| 2022 |
Zhang Y, Sun C, Li Y, Qin J, Amancherla K, Jing Y, Hu Q, Liang K, Zhang Z, Ye Y, Huang LA, Nguyen TK, Egranov SD, Zhao Z, Wu A, ... ... Hung MC, et al. Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis. Science Translational Medicine. 14: eabo1981. PMID 36322628 DOI: 10.1126/scitranslmed.abo1981 |
0.502 |
|
| 2022 |
Chu YY, Chen MK, Wei Y, Lee HH, Xia W, Wang YN, Yam C, Hsu JL, Wang HL, Chang WC, Yamaguchi H, Jiang Z, Liu C, Li CF, Nie L, ... ... Hung MC, et al. Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex. Nature Cancer. PMID 36253486 DOI: 10.1038/s43018-022-00438-2 |
0.607 |
|
| 2022 |
Ho CT, Lin SP, Tseng LM, Hung MC, Hung SC. Snail induces dormancy in disseminated luminal type A breast cancer through Src inhibition. American Journal of Cancer Research. 12: 3932-3946. PMID 36119827 |
0.356 |
|
| 2022 |
Tu J, Huo Z, Yu Y, Zhu D, Xu A, Huang MF, Hu R, Wang R, Gingold JA, Chen YH, Tsai KL, Forcioli-Conti NR, Huang SXL, Webb TR, Su J, ... ... Hung MC, et al. Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117857119. PMID 35412907 DOI: 10.1073/pnas.2117857119 |
0.765 |
|
| 2022 |
Zhao X, Wei Y, Chu YY, Li Y, Hsu JM, Jiang Z, Liu C, Hsu JL, Chang WC, Yang R, Chan LC, Qu J, Zhang S, Ying H, Yu D, ... Hung MC, et al. Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function. Cancer Research. PMID 35385574 DOI: 10.1158/0008-5472.CAN-21-2300 |
0.491 |
|
| 2022 |
Cha JH, Chan LC, Wang YN, Chu YY, Wang CH, Lee HH, Xia W, Shyu WC, Liu SP, Yao J, Chang CW, Cheng FR, Liu J, Lim SO, Hsu JL, ... ... Hung MC, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. The Journal of Biological Chemistry. 101817. PMID 35278434 DOI: 10.1016/j.jbc.2022.101817 |
0.593 |
|
| 2022 |
Wang YN, Lee HH, Wei Y, Chu YY, Xia W, Wang M, Yu D, Hung MC. An optimized protocol for PD-L1 pathological assessment with patient sample deglycosylation to improve correlation with therapeutic response. Star Protocols. 3: 101198. PMID 35243381 DOI: 10.1016/j.xpro.2022.101198 |
0.456 |
|
| 2021 |
Sun LL, Linghu DL, Hung MC. Ferroptosis: a promising target for cancer immunotherapy. American Journal of Cancer Research. 11: 5856-5863. PMID 35018229 |
0.327 |
|
| 2021 |
Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, ... ... Hung MC, et al. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nature Communications. 12: 7041. PMID 34873175 DOI: 10.1038/s41467-021-27349-7 |
0.306 |
|
| 2021 |
Lin YZ, Lee CC, Cho DY, Wang YL, Chen CY, Weng CY, Chiu SC, Hung MC, Wang SC. Suppression of breast cancer cells resistant to a pure anti-estrogen with CAR-transduced natural killer cells. American Journal of Cancer Research. 11: 4455-4469. PMID 34659898 |
0.302 |
|
| 2021 |
Wang YL, Lee CC, Shen YC, Lin PL, Wu WR, Lin YZ, Cheng WC, Chang H, Hung Y, Cho YC, Liu LC, Xia WY, Ji JH, Liang JA, Chiang SF, ... Hung MC, et al. Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA. Cell Reports. 36: 109537. PMID 34433039 DOI: 10.1016/j.celrep.2021.109537 |
0.333 |
|
| 2021 |
Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, Zhang S, Zhang Z, Kong X, Xu Q, He F, Liu D, Bai X, Sun B, Hung MC, et al. Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture. American Journal of Cancer Research. 11: 2537-2567. PMID 34249415 |
0.342 |
|
| 2021 |
Qiu Y, Yang Y, Yang R, Liu C, Hsu JM, Jiang Z, Sun L, Wei Y, Li CW, Yu D, Zhang J, Hung MC. Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer. Oncogene. PMID 34172932 DOI: 10.1038/s41388-021-01896-1 |
0.505 |
|
| 2021 |
Lee HH, Wang YN, Yang WH, Xia W, Wei Y, Chan LC, Wang YH, Jiang Z, Xu S, Yao J, Qiu Y, Hsu YH, Hwang WL, Yan M, Cha JH, ... Hung MC, et al. Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation. Nature Communications. 12: 2788. PMID 33986289 DOI: 10.1038/s41467-021-23075-2 |
0.616 |
|
| 2021 |
Jiang Z, Lim SO, Yan M, Hsu JL, Yao J, Wei Y, Chang SS, Yamaguchi H, Lee HH, Ke B, Hsu JM, Chan LC, Hortobagyi GN, Yang L, Lin C, ... ... Hung MC, et al. TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis. The Journal of Clinical Investigation. 131. PMID 33855973 DOI: 10.1172/JCI139434 |
0.472 |
|
| 2021 |
Yang R, Sun L, Li CF, Wang YH, Yao J, Li H, Yan M, Chang WC, Hsu JM, Cha JH, Hsu JL, Chou CW, Sun X, Deng Y, Chou CK, ... ... Hung MC, et al. Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy. Nature Communications. 12: 832. PMID 33547304 DOI: 10.1038/s41467-021-21099-2 |
0.672 |
|
| 2021 |
Gao Y, Chen MK, Chu YY, Yang L, Yu D, Liu Y, Hung MC. Nuclear translocation of the receptor tyrosine kinase c-MET reduces the treatment efficacies of olaparib and gemcitabine in pancreatic ductal adenocarcinoma cells. American Journal of Cancer Research. 11: 236-250. PMID 33520371 |
0.588 |
|
| 2021 |
Cho J, Min HY, Lee HJ, Hyun SY, Sim JY, Noh M, Hwang SJ, Park SH, Boo HJ, Lee HJ, Hong S, Park RW, Shin YK, Hung MC, Lee HY. RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. The Journal of Clinical Investigation. 131. PMID 33393490 DOI: 10.1172/JCI136779 |
0.382 |
|
| 2020 |
Lin CC, Huang YK, Cho CF, Lin YS, Lo CC, Kuo TT, Tseng GC, Cheng WC, Chang WC, Hsiao TH, Lai LC, Shih JY, Liu YH, Chao KSC, Hsu JL, ... ... Hung MC, et al. Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression. Theranostics. 10: 10925-10939. PMID 33042262 DOI: 10.7150/Thno.49425 |
0.375 |
|
| 2020 |
Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, ... ... Hung MC, et al. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nature Cell Biology. PMID 32929201 DOI: 10.1038/S41556-020-0575-Z |
0.371 |
|
| 2020 |
Jiang Z, Hsu JL, Li Y, Hortobagyi GN, Hung MC. Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment. Frontiers in Oncology. 10: 1197. PMID 32775303 DOI: 10.3389/Fonc.2020.01197 |
0.359 |
|
| 2020 |
Wang YN, Lee HH, Hsu JL, Yu D, Hung MC. The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis. Journal of Biomedical Science. 27: 77. PMID 32620165 DOI: 10.1186/S12929-020-00670-X |
0.466 |
|
| 2020 |
Chen MK, Hsu JL, Hung MC. Nuclear receptor tyrosine kinase transport and functions in cancer. Advances in Cancer Research. 147: 59-107. PMID 32593407 DOI: 10.1016/Bs.Acr.2020.04.010 |
0.413 |
|
| 2020 |
Zhang L, Yao J, Wei Y, Zhou Z, Li P, Qu J, Badu-Nkansah A, Yuan X, Huang YW, Fukumura K, Mao X, Chang WC, Saunus J, Lakhani S, Huse JT, ... Hung MC, et al. Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases. Science Translational Medicine. 12. PMID 32461334 DOI: 10.1126/Scitranslmed.Aaz5387 |
0.494 |
|
| 2020 |
Han Y, Wei Y, Yao J, Chu YY, Li CW, Hsu JL, Nie L, Hung MC. Inhibition of CDK2 reduces EZH2 phosphorylation and reactivates ERα expression in high-grade serous ovarian carcinoma. American Journal of Cancer Research. 10: 1194-1206. PMID 32368395 |
0.391 |
|
| 2020 |
Zhou C, Liu C, Liu W, Chen W, Yin Y, Li CW, Hsu JL, Sun J, Zhou Q, Li H, Hu B, Fu P, Atyah M, Ma Q, Xu Y, ... ... Hung MC, et al. SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway. Theranostics. 10: 4627-4643. PMID 32292519 DOI: 10.7150/Thno.42869 |
0.312 |
|
| 2020 |
Chou CK, Liu YL, Chen YI, Huang PJ, Tsou PH, Chen CT, Lee HH, Wang YN, Hsu JL, Lee JF, Yankeelov TE, Kameoka J, Yeh HC, Hung MC. Digital Receptor Occupancy Assay in Quantifying On- and Off-Target Binding Affinities of Therapeutic Antibodies. Acs Sensors. PMID 32073836 DOI: 10.1021/Acssensors.9B01736 |
0.493 |
|
| 2020 |
Hung M. Abstract IA23: Marker-guided targeted therapy, PARP inhibitors, and novel post-translational modification of PD-L1 Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Ia23 |
0.359 |
|
| 2020 |
Cha J, Yang W, Xia W, Wei Y, Chan L, Lim S, Li C, Hsu J, Wang H, Kuo C, Chang W, Hadad S, Purdie C, McCoy A, Litton J, ... ... Hung M, et al. Abstract A16: Metformin is a potential nontoxic adjuvant to enhance the efficacy of non-PDL1/PD-1 targeting immune therapies Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A16 |
0.374 |
|
| 2019 |
Saab S, Chang OS, Nagaoka K, Hung MC, Yamaguchi H. The potential role of YAP in Axl-mediated resistance to EGFR tyrosine kinase inhibitors. American Journal of Cancer Research. 9: 2719-2729. PMID 31911857 |
0.353 |
|
| 2019 |
Yen YT, Chien M, Lai YC, Chen DP, Chuong CM, Hung MC, Hung SC. PP2A Deficiency Enhances Carcinogenesis of Lgr5 Intestinal Stem Cells Both in Organoids and In Vivo. Cells. 9. PMID 31905853 DOI: 10.3390/Cells9010090 |
0.307 |
|
| 2019 |
Houl JH, Ye Z, Brosey CA, Balapiti-Modarage LPF, Namjoshi S, Bacolla A, Laverty D, Walker BL, Pourfarjam Y, Warden LS, Babu Chinnam N, Moiani D, Stegeman RA, Chen MK, Hung MC, et al. Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nature Communications. 10: 5654. PMID 31827085 DOI: 10.1038/S41467-019-13508-4 |
0.303 |
|
| 2019 |
Nie L, Wei Y, Zhang F, Hsu YH, Chan LC, Xia W, Ke B, Zhu C, Deng R, Tang J, Yao J, Chu YY, Zhao X, Han Y, Hou J, ... ... Hung MC, et al. CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer. Nature Communications. 10: 5114. PMID 31704972 DOI: 10.1038/s41467-019-13105-5 |
0.377 |
|
| 2019 |
Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, Samuel CE, Lin SH, Kabil NN, Wang J, Majidi M, Fang B, Roth JA, Vaporciyan AA, Wistuba II, Hung MC, et al. Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells. Oncogene. PMID 31554935 DOI: 10.1038/S41388-019-1010-4 |
0.381 |
|
| 2019 |
Li N, Wang Y, Neri S, Zhen Y, Fong LWR, Qiao Y, Li X, Chen Z, Stephan C, Deng W, Ye R, Jiang W, Zhang S, Yu Y, Hung MC, et al. Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling. Nature Communications. 10: 4363. PMID 31554794 DOI: 10.1038/S41467-019-12377-1 |
0.315 |
|
| 2019 |
Wu X, Park M, Sarbassova DA, Ying H, Lee MG, Bhattacharya R, Ellis L, Peterson CB, Hung MC, Lin HK, Bersimbaev RI, Song MS, Sarbassov DD. A Chirality-Dependent Action of Vitamin C in Suppressing KRAS Mutant Tumor Growth by the Oxidative Combination: Rationale for Cancer Therapeutics. International Journal of Cancer. PMID 31472018 DOI: 10.1002/Ijc.32658 |
0.353 |
|
| 2019 |
Lee HH, Wang YN, Xia W, Chen CH, Rau KM, Ye L, Wei Y, Chou CK, Wang SC, Yan M, Tu CY, Hsia TC, Chiang SF, Chao KSC, Wistuba II, ... ... Hung MC, et al. Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy. Cancer Cell. PMID 31327656 DOI: 10.1016/j.ccell.2019.06.008 |
0.472 |
|
| 2019 |
Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, ... ... Hung MC, et al. Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nature Immunology. PMID 31160797 DOI: 10.1038/S41590-019-0400-7 |
0.601 |
|
| 2019 |
Wang P, Gong Y, Guo T, Li M, Fang L, Yin S, Kamran M, Liu Y, Xu J, Xu L, Peng F, Xue X, Yang M, Hung MC, Lam EW, et al. Activation of Aurora A kinase increases YAP stability via blockage of autophagy. Cell Death & Disease. 10: 432. PMID 31160567 DOI: 10.1038/s41419-019-1664-4 |
0.352 |
|
| 2019 |
Chen MK, Du Y, Sun L, Hsu JL, Wang YH, Gao Y, Huang J, Hung MC. HOinduces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bounded retrograde trafficking mechanism. The Journal of Biological Chemistry. PMID 30962283 DOI: 10.1074/jbc.RA118.005953 |
0.326 |
|
| 2019 |
Han Y, Chen MK, Wang HL, Hsu JL, Li CW, Chu YY, Liu CX, Nie L, Chan LC, Yam C, Wang SC, He GJ, Hortobagyi GN, Tan XD, Hung MC. Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells. American Journal of Cancer Research. 9: 608-618. PMID 30949414 |
0.375 |
|
| 2019 |
Liu YL, Chou CK, Kim M, Vasisht R, Kuo YA, Ang P, Liu C, Perillo EP, Chen YA, Blocher K, Horng H, Chen YI, Nguyen DT, Yankeelov TE, Hung MC, et al. Assessing metastatic potential of breast cancer cells based on EGFR dynamics. Scientific Reports. 9: 3395. PMID 30833579 DOI: 10.1038/S41598-018-37625-0 |
0.596 |
|
| 2019 |
Park MK, Yao Y, Xia W, Setijono SR, Kim JH, Vila IK, Chiu HH, Wu Y, Billalabeitia EG, Lee MG, Kalb RG, Hung MC, Pandolfi PP, Song SJ, Song MS. PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nature Communications. 10: 636. PMID 30733438 DOI: 10.1038/S41467-019-08481-X |
0.326 |
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| 2019 |
Chen M, Du Y, Sun L, Hsu JL, Wang Y, Gao Y, Huang J, Hung M. Abstract 845: c-MET nuclear transportation via membrane-bounded retrograde trafficking in breast cancer cells Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-845 |
0.358 |
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| 2018 |
Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, ... Hung MC, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nature Genetics. PMID 30349115 DOI: 10.1038/S41588-018-0252-3 |
0.329 |
|
| 2018 |
Yam C, Hung MC, Hortobagyi GN. CDK4/6 inhibitors in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: Are we at the finish line? Oncotarget. 9: 34193-34195. PMID 30344934 DOI: 10.18632/Oncotarget.26134 |
0.376 |
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| 2018 |
Jewell BE, Liu M, Lu L, Zhou R, Tu J, Zhu D, Huo Z, Xu A, Wang D, Mata H, Jin W, Xia W, Rao PH, Zhao R, Hung MC, et al. Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation. Stem Cell Research. 33: 36-40. PMID 30312871 DOI: 10.1016/J.Scr.2018.10.003 |
0.727 |
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| 2018 |
Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nature Cell Biology. PMID 30202049 DOI: 10.1038/S41556-018-0178-0 |
0.312 |
|
| 2018 |
Xing Z, Zhang Y, Liang K, Yan L, Xiang Y, Li C, Hu Q, Jin F, Putluri V, Putluri N, Coarfa C, Sreekumar A, Park PK, Nguyen TK, Wang S, ... Hung MC, et al. Expression of long non-coding RNA YIYA promotes glycolysis in breast cancer. Cancer Research. PMID 29967256 DOI: 10.1158/0008-5472.Can-17-0385 |
0.479 |
|
| 2018 |
Chou CK, Huang PJ, Tsou PH, Wei Y, Lee HH, Wang YN, Liu YL, Shi C, Yeh HC, Kameoka J, Hung MC. A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues. Biosensors & Bioelectronics. 117: 97-103. PMID 29890396 DOI: 10.1016/J.Bios.2018.05.053 |
0.54 |
|
| 2018 |
Xu A, Zhou R, Tu J, Huo Z, Zhu D, Wang D, Gingold JA, Mata H, Rao PH, Liu M, Mohamed AMT, Kong CSL, Jewell BE, Xia W, Zhao R, ... Hung MC, et al. Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing. Stem Cell Research. 29: 215-219. PMID 29730572 DOI: 10.1016/j.scr.2018.04.013 |
0.738 |
|
| 2018 |
Zhang P, Xiao Z, Wang S, Zhang M, Wei Y, Hang Q, Kim J, Yao F, Rodriguez-Aguayo C, Ton BN, Lee M, Wang Y, Zhou Z, Zeng L, Hu X, ... Hung MC, et al. ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer. Cell Reports. 23: 823-837. PMID 29669287 DOI: 10.1016/J.Celrep.2018.03.078 |
0.34 |
|
| 2018 |
Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, ... ... Hung MC, et al. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. PMID 29606349 DOI: 10.1016/J.Ccell.2018.02.012 |
0.542 |
|
| 2018 |
Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, ... ... Hung MC, et al. Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Cancer Cell. 33: 187-201.e10. PMID 29438695 DOI: 10.1016/J.Ccell.2018.01.009 |
0.543 |
|
| 2018 |
Zhou R, Xu A, Wang D, Zhu D, Mata H, Huo Z, Tu J, Liu M, Mohamed AMT, Jewell BE, Gingold J, Xia W, Rao PH, Hung MC, Zhao R, et al. A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing. Stem Cell Research. 27: 131-135. PMID 29414603 DOI: 10.1016/j.scr.2018.01.035 |
0.746 |
|
| 2018 |
Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, ... ... Hung MC, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Molecular Cell. 69: 279-291.e5. PMID 29351847 DOI: 10.1016/J.Molcel.2017.12.024 |
0.363 |
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| 2018 |
Lim S, Li C, Hung M. Abstract 5606: Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1 Cancer Research. 78: 5606-5606. DOI: 10.1158/1538-7445.Am2018-5606 |
0.33 |
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| 2018 |
Hossain MB, Shifat R, Kim DK, Rivera-Molina Y, Martinez FP, Jiang H, Nguyen T, Johnson DG, Bedford MT, Hung M, Sulman EP, Lang F, Sawaya R, Fueyo J, Gomez-Manzano C. Abstract 3205: Histone tyrosine phosphorylation determines glioblastoma cell survival Cancer Research. 78: 3205-3205. DOI: 10.1158/1538-7445.Am2018-3205 |
0.416 |
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| 2018 |
Liu Y, Chou C, Kim M, Vasisht R, Liu C, Perillo EP, Horng H, Hung M, Dunn AK, Yeh T. Effect of Epithelial-Mesenchymal Transition on EGFR Dynamics Revealed by Single-Particle Tracking Biophysical Journal. 114: 534a. DOI: 10.1016/J.Bpj.2017.11.2920 |
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| 2017 |
Korphaisarn K, Chou CK, Xia WY, Clarke CN, Katkhuda R, Davis JS, Raghav KP, Liao HW, Wu JY, Menter DG, Maru DM, Hung MC, Kopetz S. Arginine methylation of EGFR: a new biomarker for predicting resistance to anti-EGFR treatment. American Journal of Cancer Research. 7: 2587-2599. PMID 29312811 |
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| 2017 |
Huang PJ, Chou CK, Chen CT, Yamaguchi H, Qu J, Muliana A, Hung MC, Kameoka J. Pneumatically Actuated Soft Micromold Device for Fabricating Collagen and Matrigel Microparticles. Soft Robotics. 4: 390-399. PMID 29251562 DOI: 10.1089/Soro.2016.0073 |
0.534 |
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| 2017 |
Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, ... Hung MC, et al. JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. The Journal of Clinical Investigation. PMID 29130936 DOI: 10.1172/Jci91553 |
0.584 |
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| 2017 |
Nilsson MB, Sun H, Diao L, Tong P, Liu D, Li L, Fan Y, Poteete A, Lim SO, Howells K, Haddad V, Gomez D, Tran H, Pena GA, Sequist LV, ... ... Hung MC, et al. Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers. Science Translational Medicine. 9. PMID 29118262 DOI: 10.1126/Scitranslmed.Aao4307 |
0.334 |
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| 2017 |
Yamaguchi H, Du Y, Nakai K, Ding M, Chang SS, Hsu JL, Yao J, Wei Y, Nie L, Jiao S, Chang WC, Chen CH, Yu Y, Hortobagyi GN, Hung MC. EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer. Oncogene. PMID 28925391 DOI: 10.1038/Onc.2017.311 |
0.355 |
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| 2017 |
Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Molecular Cell. 67: 733-743.e4. PMID 28844863 DOI: 10.1016/J.Molcel.2017.07.026 |
0.548 |
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| 2017 |
Hossain MB, Shifat R, Li J, Luo X, Hess KR, Rivera-Molina Y, Martinez FP, Jiang H, Lang FF, Hung MC, Fueyo J, Gomez-Manzano C. TIE2 associates with caveolae and regulates caveolin-1 to promote their nuclear translocation. Molecular and Cellular Biology. PMID 28760776 DOI: 10.1128/Mcb.00142-17 |
0.429 |
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| 2017 |
Lin X, Chen W, Wei F, Zhou BP, Hung MC, Xie X. POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells. International Journal of Cancer. PMID 28214331 DOI: 10.1002/ijc.30658 |
0.346 |
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| 2017 |
Jiao S, Xia W, Yamaguchi H, Wei Y, Chen MK, Hsu JM, Hsu JL, Yu WH, Du Y, Lee HH, Li CW, Chou CK, Lim SO, Chang SS, Litton JK, ... ... Hung MC, et al. PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28167507 DOI: 10.1158/1078-0432.CCR-16-3215 |
0.496 |
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| 2017 |
Vila IK, Yao Y, Kim G, Xia W, Kim H, Kim SJ, Park MK, Hwang JP, González-Billalabeitia E, Hung MC, Song SJ, Song MS. A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. Cancer Cell. PMID 28162974 DOI: 10.1016/j.ccell.2017.01.003 |
0.312 |
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| 2017 |
Chen HA, Chang YW, Tseng CF, Chiu CF, Hong CC, Wang W, Wang MY, Hsiao M, Ma JT, Chen CH, Jiang SS, Wu CH, Hung MC, Huang MT, Su JL. Erratum to: E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer. Annals of Surgical Oncology. PMID 28160139 DOI: 10.1245/s10434-017-5769-7 |
0.322 |
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| 2017 |
Zuo X, Xu W, Xu M, Tian R, Moussalli MJ, Mao F, Zheng X, Wang J, Morris JS, Gagea M, Eng C, Kopetz S, Maru DM, Rashid A, Broaddus R, ... Hung MC, et al. Metastasis regulation by PPARD expression in cancer cells. Jci Insight. 2: e91419. PMID 28097239 DOI: 10.1172/Jci.Insight.91419 |
0.46 |
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| 2017 |
Korphaisarn K, Chou C, Xia W, Clarke C, Davis JS, Liao H, Crosby S, Manuel S, Wu J, Menter D, Hung M, Kopetz S. Arginine methylation of EGFR in circulating tumor cells: A new biomarker for predicting resistance to anti-EGFR agents. Journal of Clinical Oncology. 35: 3590-3590. DOI: 10.1200/Jco.2017.35.15_Suppl.3590 |
0.586 |
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| 2017 |
Lim S, Li C, Hung M. Abstract B47: Stabilization of programmed death ligand-1 by epidermal growth factor enhances cancer cell immune escape Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B47 |
0.349 |
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| 2017 |
Goverdhan A, Lee H, Havranek O, Davis RE, Hung M. Abstract 13: PRMT1 as a therapeutic target in diffuse large B-cell lymphoma Clinical Cancer Research. 23: 13-13. DOI: 10.1158/1557-3265.Hemmal17-13 |
0.381 |
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| 2017 |
Nie L, Wei Y, Yamaguchi H, Huo L, Xia W, Deng R, Tang J, Zhu C, Ke B, Hung M. Abstract LB-131: Targeting expression of EZH2 with increased H3K27 trimethylation activity drives and synergizes with oncogene to promote mammary tumorigenesis in genetically engineered mouse models Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-131 |
0.44 |
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| 2017 |
Hossain MB, Shifat R, Li J, Rivera-Mokina Y, Martinez FP, Johnson DG, Bedford MT, Hung M, Sulman EP, Lang F, Sawaya R, Fueyo J, Gomez-Manzano C. Abstract 5854: TIE2-mediated epigenetic marks regulate therapeutic resistance of glioblastoma Cancer Research. 77: 5854-5854. DOI: 10.1158/1538-7445.Am2017-5854 |
0.302 |
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| 2017 |
Lim S, Li C, Hung M. Abstract 4713: Deubiquitination and stabilization of programmed cell death-ligand 1 by CSN5 Cancer Research. 77: 4713-4713. DOI: 10.1158/1538-7445.Am2017-4713 |
0.373 |
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| 2016 |
Rezaeian AH, Li CF, Wu CY, Zhang X, Delacerda J, You MJ, Han F, Cai Z, Jeong YS, Jin G, Phan L, Chou PC, Lee MH, Hung MC, Sarbassov D, et al. A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis. Nature Cell Biology. PMID 27918549 DOI: 10.1038/ncb3445 |
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| 2016 |
Hsu JL, Hung MC. The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer. Cancer Metastasis Reviews. PMID 27913999 DOI: 10.1007/s10555-016-9649-6 |
0.342 |
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| 2016 |
Lim SO, Li CW, Xia W, Cha JH, Chan LC, Wu Y, Chang SS, Lin WC, Hsu JM, Hsu YH, Kim T, Chang WC, Hsu JL, Yamaguchi H, Ding Q, ... ... Hung MC, et al. Deubiquitination and Stabilization of PD-L1 by CSN5. Cancer Cell. PMID 27866850 DOI: 10.1016/J.Ccell.2016.10.010 |
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| 2016 |
Liu YL, Perillo EP, Liu C, Yu P, Chou CK, Hung MC, Dunn AK, Yeh HC. Segmentation of 3D Trajectories Acquired by TSUNAMI Microscope: An Application to EGFR Trafficking. Biophysical Journal. 111: 2214-2227. PMID 27851944 DOI: 10.1016/J.Bpj.2016.09.041 |
0.484 |
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| 2016 |
Wang Y, Hsu JM, Kang Y, Wei Y, Lee PC, Chang SJ, Hsu YH, Hsu JL, Wang HL, Chang WC, Li CW, Liao HW, Chang SS, Xia W, Ko HW, ... ... Hung MC, et al. Oncogenic functions of Gli in pancreatic adenocarcinoma are supported by its PRMT1-mediated methylation. Cancer Research. PMID 27758883 DOI: 10.1158/0008-5472.CAN-16-0715 |
0.571 |
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| 2016 |
Hossain MB, Shifat R, Johnson DG, Bedford MT, Gabrusiewicz KR, Cortes-Santiago N, Luo X, Lu Z, Ezhilarasan R, Sulman EP, Jiang H, Li SS, Lang FF, Tyler J, Hung MC, et al. TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Science Advances. 2: e1501290. PMID 27757426 DOI: 10.1126/Sciadv.1501290 |
0.34 |
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| 2016 |
Du Y, Yamaguchi H, Wei Y, Hsu JL, Wang HL, Hsu YH, Lin WC, Yu WH, Leonard PG, Lee GR, Chen MK, Nakai K, Hsu MC, Chen CT, Sun Y, ... ... Hung MC, et al. Corrigendum: Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nature Medicine. 22: 1192. PMID 27711065 DOI: 10.1038/Nm1016-1192C |
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| 2016 |
Nakai K, Hung MC, Yamaguchi H. A perspective on anti-EGFR therapies targeting triple-negative breast cancer. American Journal of Cancer Research. 6: 1609-1623. PMID 27648353 |
0.312 |
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| 2016 |
Li CW, Lim SO, Xia W, Lee HH, Chan LC, Kuo CW, Khoo KH, Chang SS, Cha JH, Kim T, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Ding Q, ... ... Hung MC, et al. Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nature Communications. 7: 12632. PMID 27572267 DOI: 10.1038/Ncomms12632 |
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| 2016 |
Lee CJ, Hsu LS, Yue CH, Lin H, Chiu YW, Lin YY, Huang CY, Hung MC, Liu JY. MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells. Oncotarget. PMID 27542222 DOI: 10.18632/oncotarget.11337 |
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| 2016 |
Ko HW, Lee HH, Huo L, Xia W, Yang CC, Hsu JL, Li LY, Lai CC, Chan LC, Cheng CC, Labaff AM, Liao HW, Lim SO, Li CW, Wei Y, ... Hung MC, et al. GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget. PMID 27494834 DOI: 10.18632/oncotarget.11008 |
0.843 |
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| 2016 |
Liu CC, Lin SP, Hsu HS, Yang SH, Lin CH, Yang MH, Hung MC, Hung SC. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nature Communications. 7: 11798. PMID 27306323 DOI: 10.1038/ncomms11798 |
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| 2016 |
Chang TY, Chen HA, Chiu CF, Chang YW, Kuo TC, Tseng PC, Wang W, Hung MC, Su JL. Dicer elicits paclitaxel chemosensitization and suppresses cancer stemness in breast cancer by repressing AXL. Cancer Research. PMID 27216190 DOI: 10.1158/0008-5472.CAN-15-2555 |
0.361 |
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| 2016 |
Chen MK, Hung MC. Regulation of therapeutic resistance in cancers by receptor tyrosine kinases. American Journal of Cancer Research. 6: 827-42. PMID 27186434 |
0.357 |
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| 2016 |
Hsu MC, Hung WC, Yamaguchi H, Lim SO, Liao HW, Tsai CH, Hung MC. Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway. American Journal of Cancer Research. 6: 628-38. PMID 27152240 |
0.4 |
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| 2016 |
Chang CC, Zhang C, Zhang Q, Sahin O, Wang H, Xu J, Xiao Y, Zhang J, Rehman SK, Li P, Hung MC, Behbod F, Yu D. Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression. Oncotarget. PMID 27150057 DOI: 10.18632/Oncotarget.9136 |
0.641 |
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| 2016 |
Chou CK, Tsou PH, Hsu JL, Lee HH, Wang YN, Kameoka J, Hung MC. Analysis of Individual Signaling Complexes by mMAPS, a Flow-Proteometric System. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 114: 20.11.1-20.11.22. PMID 27038387 DOI: 10.1002/0471142727.Mb2011S114 |
0.515 |
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| 2016 |
Chou CK, Fan CC, Lin PS, Liao PY, Tung JC, Hsieh CH, Hung MC, Chen CH, Chang WC. Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis. Oncotarget. PMID 27013588 DOI: 10.18632/oncotarget.8264 |
0.584 |
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| 2016 |
Zheng F, Yue C, Li G, He B, Cheng W, Wang X, Yan M, Long Z, Qiu W, Yuan Z, Xu J, Liu B, Shi Q, Lam EW, Hung MC, et al. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nature Communications. 7: 10180. PMID 26782714 DOI: 10.1038/Ncomms10180 |
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| 2016 |
Du Y, Yamaguchi H, Wei Y, Hsu JL, Wang HL, Hsu YH, Lin WC, Yu WH, Leonard PG, Lee GR, Chen MK, Nakai K, Hsu MC, Chen CT, Sun Y, ... Hung MC, et al. Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nature Medicine. PMID 26779812 DOI: 10.1038/Nm.4032 |
0.38 |
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| 2016 |
Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D, Djukovic D, Gu H, Chang WC, Wang HL, Chen ML, Huo L, Chen CH, ... Hung MC, et al. EGFR signaling enhances aerobic glycolysis in triple negative breast cancer cells to promote tumor growth and immune escape. Cancer Research. PMID 26759242 DOI: 10.1158/0008-5472.Can-15-2478 |
0.368 |
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| 2016 |
Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, ... Hung MC, et al. AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent Twist1 degradation. Cancer Research. PMID 26759241 DOI: 10.1158/0008-5472.CAN-15-1941 |
0.834 |
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| 2016 |
Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, Wang C, Hawke DH, Wang S, Zhang Y, Wei Y, Ma G, Park PK, Zhou J, Zhou Y, ... Hung MC, et al. The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. Nature Cell Biology. PMID 26751287 DOI: 10.1038/Ncb3295 |
0.348 |
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| 2016 |
Niu N, Zhang J, Zhang N, Mercado-Uribe I, Tao F, Han Z, Pathak S, Multani A, Kuang J, Yao J, Bast R, Sood A, Hung M, Liu J. Abstract LB-119: Single-cell live imaging of paclitaxel-resistant cancer cell generation Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-119 |
0.409 |
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| 2016 |
Liao H, Hsu J, Xia W, Hung M. Abstract LB-002: Methylation of the EGF receptor regulates signaling and therapeutic response Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-002 |
0.388 |
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| 2016 |
Liu Y, Perillo EP, Liu C, Yu PM, Chou C, Hung M, Dunn AK, Yeh T. Dynamics of EGFR Trafficking from Membrane into Deep Cytoplasm Revealed by a Spatiotemporally Multiplexed 3D Tracking Microscope Biophysical Journal. 110: 638a. DOI: 10.1016/J.Bpj.2015.11.3416 |
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| 2015 |
Rahal OM, Nie L, Chan LC, Li CW, Hsu YH, Hsu J, Yu D, Hung MC. Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells. American Journal of Cancer Research. 5: 3624-34. PMID 26885451 |
0.593 |
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| 2015 |
Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK, Tsou PH, Yamaguchi H, Fang YF, Lee HJ, Lee HH, Tai SK, Yang MH, ... ... Hung MC, et al. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. The Journal of Clinical Investigation. PMID 26571401 DOI: 10.1172/Jci82826 |
0.566 |
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| 2015 |
Han B, Qu Y, Jin Y, Yu Y, Deng N, Wawrowsky K, Zhang X, Li N, Bose S, Wang Q, Sakkiah S, Abrol R, Jensen TW, Berman BP, Tanaka H, ... Hung MC, et al. FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer. Cell Reports. 13: 1046-1058. PMID 26565916 DOI: 10.1016/J.Celrep.2015.09.063 |
0.393 |
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| 2015 |
Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, ... Hung MC, et al. Erythropoietin Stimulates Tumor Growth via EphB4. Cancer Cell. PMID 26481148 DOI: 10.1016/J.Ccell.2015.09.008 |
0.829 |
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| 2015 |
Hu D, Gur M, Zhou Z, Gamper A, Hung MC, Fujita N, Lan L, Bahar I, Wan Y. Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nature Communications. 6: 8419. PMID 26420673 DOI: 10.1038/Ncomms9419 |
0.316 |
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| 2015 |
Yang CC, LaBaff A, Wei Y, Nie L, Xia W, Huo L, Yamaguchi H, Hsu YH, Hsu JL, Liu D, Lang J, Du Y, Lien HC, Li LY, Deng R, ... ... Hung MC, et al. Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. American Journal of Translational Research. 7: 1009-20. PMID 26279746 |
0.826 |
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| 2015 |
Perillo EP, Liu YL, Huynh K, Liu C, Chou CK, Hung MC, Yeh HC, Dunn AK. Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination. Nature Communications. 6: 7874. PMID 26219252 DOI: 10.1038/Ncomms8874 |
0.489 |
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| 2015 |
Timsah Z, Ahmed Z, Ivan C, Berrout J, Gagea M, Zhou Y, Pena GN, Hu X, Vallien C, Kingsley CV, Lu Y, Hancock JF, Liu J, Gladden AB, Mills GB, ... Hung MC, et al. Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene. PMID 26212011 DOI: 10.1038/Onc.2015.279 |
0.481 |
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| 2015 |
Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, ... Hung MC, et al. The ZNF304-integrin axis protects against anoikis in cancer. Nature Communications. 6: 7351. PMID 26081979 DOI: 10.1038/Ncomms8351 |
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| 2015 |
Sun Y, Ponz-Sarvise M, Chang SS, Chang WC, Chen CH, Hsu JL, Hung MC. Proteasome inhibition enhances the killing effect of BikDD gene therapy. American Journal of Translational Research. 7: 319-27. PMID 25901200 |
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| 2015 |
Sorokin AV, Nair BC, Wei Y, Aziz KE, Evdokimova V, Hung MC, Chen J. Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis. Cancer Research. 75: 1846-58. PMID 25877877 DOI: 10.1158/0008-5472.Can-14-2718 |
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| 2015 |
Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR. Modeling familial cancer with induced pluripotent stem cells. Cell. 161: 240-54. PMID 25860607 DOI: 10.1016/J.Cell.2015.02.045 |
0.801 |
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| 2015 |
Xu J, Acharya S, Sahin O, Zhang Q, Saito Y, Yao J, Wang H, Li P, Zhang L, Lowery FJ, Kuo WL, Xiao Y, Ensor J, Sahin AA, Zhang XH, ... Hung MC, et al. 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2. Cancer Cell. 27: 177-92. PMID 25670079 DOI: 10.1016/J.Ccell.2014.11.025 |
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| 2015 |
Boulbes DR, Arold ST, Chauhan GB, Blachno KV, Deng N, Chang WC, Jin Q, Huang TH, Hsu JM, Brady SW, Bartholomeusz C, Ladbury JE, Stone S, Yu D, Hung MC, et al. HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer. Molecular Oncology. 9: 586-600. PMID 25435280 DOI: 10.1016/J.Molonc.2014.10.011 |
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| 2015 |
Chen HA, Chang YW, Tseng CF, Chiu CF, Hong CC, Wang W, Wang MY, Hsiao M, Ma JT, Chen CH, Jiang SS, Wu CH, Hung MC, Huang MT, Su JL. E1A-mediated inhibition of HSPA5 suppresses cell migration and invasion in triple-negative breast cancer. Annals of Surgical Oncology. 22: 889-98. PMID 25212833 DOI: 10.1245/s10434-014-4061-3 |
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| 2015 |
Chang S, Yamaguchi H, Hung M. Abstract B03: Cisplatin-resistant cells possess collateral sensitivity to folate antimetabolites Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B03 |
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| 2015 |
Xu J, Acharya S, Sahin O, Zhang L, Lowery FJ, Sahin AA, Zhang XH-, Hung M, Yu D. Abstract LB-202: 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2 Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-202 |
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| 2015 |
Lee D, Su J, Kim HS, Chang B, Zhao R, Papatsenko D, Yuan Y, Gingold J, Xia W, Darr H, Schaniel C, Mirzayans R, Hung M, Lemischka IR. Abstract 5129: Model osteosarcoma by Li-Fraumeni syndrome patient-specific induced pluripotent stem cells Cancer Research. 75: 5129-5129. DOI: 10.1158/1538-7445.Am2015-5129 |
0.705 |
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| 2015 |
Chou C, Lee H, Tsou P, Chen C, Hsu J, Yamaguchi H, Wang Y, Hsu JL, Lee J, Kameoka J, Hung M. Abstract 5120: Using flow-proteometric platform to analyze individual signaling complexes in tumor tissue Cancer Research. 75: 5120-5120. DOI: 10.1158/1538-7445.Am2015-5120 |
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| 2015 |
Chen J, Chen J, Zhang J, Phan L, Muñoz NM, Katz LH, Gi Y, Menon VK, Shin J, Jeong YS, Jogunoori W, Farci P, Shetty K, Su X, Pandita TK, ... ... Hung M, et al. Abstract 3900: Genomic landscape of human cancer reveals dysregulated TGF-β signaling with prognostic significance Cancer Research. 75: 3900-3900. DOI: 10.1158/1538-7445.Am2015-3900 |
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| 2015 |
Hossain MB, Shifat R, Johnson DG, Bedford MT, Hung M, Cortes-Santiago N, Gabrusiewicz K, Gumin J, Ezhilarasan R, Sulman EP, Lang F, Sawaya R, Yung WKA, Fueyo J, Gomez-Manzano C. Abstract 3298: ABL1 is required for Tie2-mediated DNA repair in brain tumor stem cells Cancer Research. 75: 3298-3298. DOI: 10.1158/1538-7445.Am2015-3298 |
0.398 |
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| 2015 |
Nie L, Wei Y, LaBaff A, Yang C, Xia W, Huo L, Liu D, Hsu Y, Hortobagyi GN, Yao J, Kleer CG, Hung M. Abstract 2895: Phosphorylation of EZH2 at T416 by CDK2 promotes development of mammary tumors with basal-like phenotype Cancer Research. 75: 2895-2895. DOI: 10.1158/1538-7445.Am2015-2895 |
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| 2015 |
Rojas A, Zhang P, Wang Y, Munoz NM, Xiao L, Wang J, Gores GJ, Hung M, Blechacz BRA. Abstract 1962: TGF-β/SMAD2 signaling drives tumor-progression via c-KIT/STAT3-signaling in advanced HCC Cancer Research. 75: 1962-1962. DOI: 10.1158/1538-7445.Am2015-1962 |
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| 2015 |
Hossain MB, Shifat R, Johnson DG, Bedford MT, Hung M, Gabrusiewicz K, Gumin J, Ezhilarasan R, Sulman EP, Lang F, Tyler J, Sawaya R, Yung WA, Fueyo J, Gomez-Manzano C. RTRB-10TYROSINE KINASE RECEPTOR TIE2 REGULATES DNA REPAIR THROUGH THE PROTO-ONCOGENE ABL1 IN BRAIN TUMOR STEM CELLS Neuro-Oncology. 17: v197.2-v197. DOI: 10.1093/Neuonc/Nov231.10 |
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| 2014 |
Huo L, Li CW, Huang TH, Lam YC, Xia W, Tu C, Chang WC, Hsu JL, Lee DF, Nie L, Yamaguchi H, Wang Y, Lang J, Li LY, Chen CH, ... ... Hung MC, et al. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. American Journal of Translational Research. 6: 649-63. PMID 25628777 |
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Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, Park PK, Qin L, Wei Y, Hawke DH, Hung MC, Lin C, Yang L. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 159: 1110-25. PMID 25416949 DOI: 10.1016/j.cell.2014.10.013 |
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Chang YW, Chen HA, Tseng CF, Hong CC, Ma JT, Hung MC, Wu CH, Huang MT, Su JL. De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells. Oncotarget. 5: 10558-70. PMID 25301734 DOI: 10.18632/ONCOTARGET.2510 |
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Zhang P, Wei Y, Wang L, Debeb BG, Yuan Y, Zhang J, Yuan J, Wang M, Chen D, Sun Y, Woodward WA, Liu Y, Dean DC, Liang H, Hu Y, ... ... Hung MC, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nature Cell Biology. 16: 864-75. PMID 25086746 DOI: 10.1038/Ncb3013 |
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Khotskaya YB, Goverdhan A, Shen J, Ponz-Sarvise M, Chang SS, Hsu MC, Wei Y, Xia W, Yu D, Hung MC. S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer. American Journal of Translational Research. 6: 361-76. PMID 25075253 |
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Thirumurthi U, Shen J, Xia W, LaBaff AM, Wei Y, Li CW, Chang WC, Chen CH, Lin HK, Yu D, Hung MC. MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Science Signaling. 7: ra71. PMID 25074979 DOI: 10.1126/Scisignal.2005076 |
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Debeb BG, Gong Y, Atkinson RL, Sneige N, Huo L, Gonzalez-Angulo AM, Hung MC, Valero V, Ueno NT, Woodward WA. EZH2 expression correlates with locoregional recurrence after radiation in inflammatory breast cancer. Journal of Experimental & Clinical Cancer Research : Cr. 33: 58. PMID 25051981 DOI: 10.1186/S13046-014-0058-9 |
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Yamaguchi H, Hung MC. Regulation and Role of EZH2 in Cancer. Cancer Research and Treatment : Official Journal of Korean Cancer Association. 46: 209-22. PMID 25038756 DOI: 10.4143/crt.2014.46.3.209 |
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Hsu YH, Yao J, Chan LC, Wu TJ, Hsu JL, Fang YF, Wei Y, Wu Y, Huang WC, Liu CL, Chang YC, Wang MY, Li CW, Shen J, Chen MK, ... Hung MC, et al. Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer. Cancer Research. 74: 4822-35. PMID 24970481 DOI: 10.1158/0008-5472.Can-14-0584 |
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Chao CH, Chang CC, Wu MJ, Ko HW, Wang D, Hung MC, Yang JY, Chang CJ. MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. The Journal of Clinical Investigation. 124: 3093-106. PMID 24911147 DOI: 10.1172/JCI73351 |
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Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Stroehlein JR, Martin JF, ... Hung MC, et al. Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties. Cancer Research. 74: 4170-82. PMID 24906622 DOI: 10.1158/0008-5472.Can-13-3569 |
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Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, ... ... Hung MC, et al. Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Molecular Cell. 54: 960-74. PMID 24857548 DOI: 10.1016/j.molcel.2014.04.024 |
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Chou CK, Lee HH, Tsou PH, Chen CT, Hsu JM, Yamaguchi H, Wang YN, Lee HJ, Hsu JL, Lee JF, Kameoka J, Hung MC. mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes. Science Signaling. 7: rs1. PMID 24595109 DOI: 10.1126/Scisignal.2004620 |
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Zhang K, Chou CK, Xia X, Hung MC, Qin L. Block-Cell-Printing for live single-cell printing. Proceedings of the National Academy of Sciences of the United States of America. 111: 2948-53. PMID 24516129 DOI: 10.1073/Pnas.1313661111 |
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Chang YW, Hung MC, Su JL. The anti-tumor activity of E1A and its implications in cancer therapy. Archivum Immunologiae Et Therapiae Experimentalis. 62: 195-204. PMID 24504082 DOI: 10.1007/s00005-014-0273-2 |
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| 2014 |
Xue J, Lin X, Chiu WT, Chen YH, Yu G, Liu M, Feng XH, Sawaya R, Medema RH, Hung MC, Huang S. Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis. The Journal of Clinical Investigation. 124: 564-79. PMID 24382352 DOI: 10.1172/Jci71104 |
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Khotskaya YB, Beck BH, Hurst DR, Han Z, Xia W, Hung MC, Welch DR. Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix. Molecular Carcinogenesis. 53: 1011-26. PMID 24000122 DOI: 10.1002/Mc.22068 |
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Yamaguchi H, Chang SS, Hsu JL, Hung MC. Signaling cross-talk in the resistance to HER family receptor targeted therapy. Oncogene. 33: 1073-81. PMID 23542173 DOI: 10.1038/Onc.2013.74 |
0.388 |
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| 2014 |
Du Y, Shen J, Hsu JL, Han Z, Hsu MC, Yang CC, Kuo HP, Wang YN, Yamaguchi H, Miller SA, Hung MC. Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Oncogene. 33: 756-70. PMID 23376851 DOI: 10.1038/onc.2013.1 |
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| 2014 |
Khotskaya YB, Goverdhan A, Shen J, Sarvice MP, Chang S, Hsu M, Wei Y, Xia W, Steeg P, Yu D, Hung M. Abstract A49: S6K1 promotes invasiveness of breast cancer cells in a novel model of triple-negative breast cancer metastasis Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-A49 |
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| 2014 |
Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Cascone T, Giri D, Kim J, Ye Y, Multani A, Chan C, Erez B, Saigal B, Lin H, ... Hung M, et al. Abstract 5146: The histone demethylase KDM2A is a new promoter of tumorigenesis, drug target and negative prognostic biomarker for non-small cell lung cancer Cancer Research. 74: 5146-5146. DOI: 10.1158/1538-7445.Am2014-5146 |
0.454 |
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| 2014 |
Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Jin J, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Martin JF, ... Hung M, et al. Abstract 3896: The Hippo coactivator YAP1 upregulates SOX9 and endows cancer stem cell properties in non-transformed cells and esophageal cancer cells Cancer Research. 74: 3896-3896. DOI: 10.1158/1538-7445.Am2014-3896 |
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| 2014 |
Chen J, Chen J, Gi Y, Katz LH, Shin J, Phan L, Jogunoori W, Shukla V, Mishra B, Li S, Javle M, Hung M, Mishra L. Abstract 2784: Targeting TGF-β regulated E3 ligases: a novel therapeutic approach for primary liver cancer Cancer Research. 74: 2784-2784. DOI: 10.1158/1538-7445.Am2014-2784 |
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| 2014 |
Chen J, Chen J, Gi Y, Katz LH, Shin J, Phan LM, Jogunoori W, Shukla V, Mishra B, Li S, Javle M, Hung M, Mishra L. 641 TGF-β? Regulated E3 Ligase Are Novel Therapeutic Targets for Primary Liver Cancer Gastroenterology. 146: S-918. DOI: 10.1016/S0016-5085(14)63337-0 |
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| 2013 |
Zhang J, Zhang P, Wei Y, Piao HL, Wang W, Maddika S, Wang M, Chen D, Sun Y, Hung MC, Chen J, Ma L. Deubiquitylation and stabilization of PTEN by USP13. Nature Cell Biology. 15: 1486-94. PMID 24270891 DOI: 10.1038/Ncb2874 |
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| 2013 |
Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Giri D, Cascone T, Kim JH, Ye Y, Multani AS, Chan CH, Erez B, Saigal B, Chung J, ... ... Hung MC, et al. KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. The Journal of Clinical Investigation. 123: 5231-46. PMID 24200691 DOI: 10.1172/Jci68642 |
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| 2013 |
Saldana SM, Lee HH, Lowery FJ, Khotskaya YB, Xia W, Zhang C, Chang SS, Chou CK, Steeg PS, Yu D, Hung MC. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. Plos One. 8: e73406. PMID 24039934 DOI: 10.1371/Journal.Pone.0073406 |
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| 2013 |
Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward WA, Reuben JM, Warner SL, Bearss DJ, Hortobagyi GN, Hung MC, Ueno NT. TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase. Cancer Research. 73: 6516-25. PMID 24014597 DOI: 10.1158/0008-5472.Can-13-0967 |
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| 2013 |
Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell. 154: 556-68. PMID 23911321 DOI: 10.1016/j.cell.2013.06.048 |
0.35 |
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| 2013 |
Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, ... ... Hung MC, et al. Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. Cancer Cell. 23: 796-810. PMID 23764002 DOI: 10.1016/j.ccr.2013.04.027 |
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| 2013 |
Yu YL, Chou RH, Liang JH, Chang WJ, Su KJ, Tseng YJ, Huang WC, Wang SC, Hung MC. Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides. Plos One. 8: e61362. PMID 23593472 DOI: 10.1371/journal.pone.0061362 |
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| 2013 |
Yu YL, Chou RH, Shyu WC, Hsieh SC, Wu CS, Chiang SY, Chang WJ, Chen JN, Tseng YJ, Lin YH, Lee W, Yeh SP, Hsu JL, Yang CC, Hung SC, ... Hung MC, et al. Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke. Embo Molecular Medicine. 5: 531-47. PMID 23526793 DOI: 10.1002/emmm.201201783 |
0.777 |
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| 2013 |
Dong C, Yuan T, Wu Y, Wang Y, Fan TW, Miriyala S, Lin Y, Yao J, Shi J, Kang T, Lorkiewicz P, St Clair D, Hung MC, Evers BM, Zhou BP. Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell. 23: 316-31. PMID 23453623 DOI: 10.1016/J.Ccr.2013.01.022 |
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| 2013 |
Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes & Development. 27: 274-87. PMID 23388826 DOI: 10.1101/Gad.203760.112 |
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| 2013 |
Hsia TC, Tu CY, Chen YJ, Wei YL, Yu MC, Hsu SC, Tsai SL, Chen WS, Yeh MH, Yen CJ, Yu YL, Huang TC, Huang CY, Hung MC, Huang WC. Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction enhances the aggressiveness of triple-negative breast cancer cells. Molecular Pharmacology. 83: 857-69. PMID 23355539 DOI: 10.1124/mol.112.082743 |
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| 2013 |
Liu CM, Hsieh CL, He YC, Lo SJ, Liang JA, Hsieh TF, Josson S, Chung LW, Hung MC, Sung SY. In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression. Plos One. 8: e53795. PMID 23342005 DOI: 10.1371/Journal.Pone.0053795 |
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Huang WH, Chang MC, Tsai KS, Hung MC, Chen HL, Hung SC. Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. Oncogene. 32: 4343-54. PMID 23085755 DOI: 10.1038/Onc.2012.458 |
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Sher YP, Chang CM, Juo CG, Chen CT, Hsu JL, Lin CY, Han Z, Shiah SG, Hung MC. Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth. Oncogene. 32: 1082-90. PMID 22562248 DOI: 10.1038/Onc.2012.134 |
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| 2013 |
Wei Y, Chang S, Wang H, Xia W, Hung M. Abstract 5351: Phosphorylation of EZH2 at Thr487 is a marker for good prognosis in pancreatic cancer patients. Cancer Research. 73: 5351-5351. DOI: 10.1158/1538-7445.Am2013-5351 |
0.392 |
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| 2013 |
Chou C, Lee H, Tsou P, Yamaguchi H, Wang Y, Lee H, Kameoka J, Hung M. Abstract 5169: Flow-proteometric analysis of single signaling complex. Cancer Research. 73: 5169-5169. DOI: 10.1158/1538-7445.Am2013-5169 |
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| 2013 |
Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward W, Reuben JM, Hortobagyi GN, Hung M, Ueno NT. Abstract 3032: Tazarotene-induced gene 1 promotes tumorigenicity and invasiveness of inflammatory breast cancer through receptor tyrosine kinase Axl. Cancer Research. 73: 3032-3032. DOI: 10.1158/1538-7445.Am2013-3032 |
0.442 |
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| 2013 |
Lim S, Li C, Chang S, Shen J, Hung M. Abstract 3027: A novel function of EGFR in epigenetic modulation via hMOF in breast cancer . Cancer Research. 73: 3027-3027. DOI: 10.1158/1538-7445.Am2013-3027 |
0.467 |
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| 2013 |
Rojas A, Cromheecke J, Lee M, Hung M, Blechacz B. Abstract 2046: TGF-β drives tumor-progression via JAK/STAT3-signaling in advanced HCC. Cancer Research. 73: 2046-2046. DOI: 10.1158/1538-7445.Am2013-2046 |
0.323 |
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| 2013 |
Holder AM, Adkins F, Akcakanat A, Chen H, Do K, Hung M, Meric-Bernstam F. Abstract 1496: Epithelial to mesenchymal transition and rapamycin sensitivity in cancer cell lines. Cancer Research. 73: 1496-1496. DOI: 10.1158/1538-7445.Am2013-1496 |
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| 2013 |
Yamaguchi H, Hsu JL, Chen C, Wang Y, Hsu M, Chang S, Du Y, Ko H, Herbst RS, Hung M. Abstract 1051: EGFR inhibitors attenuate caspase-independent cell death and confer negative effects on cisplatin . Cancer Research. 73: 1051-1051. DOI: 10.1158/1538-7445.Am2013-1051 |
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| 2013 |
Zuo M, Rashid A, Churi C, Hung M, Javle M. Abstract C171: Novel therapeutic strategies targeting the hedgehog signaling pathway and mTOR pathway in biliary tract cancer (BTC). Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C171 |
0.482 |
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| 2012 |
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KKC, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, et al. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis. Cell. 151: 913-914. PMID 30360292 DOI: 10.1016/J.Cell.2012.10.025 |
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| 2012 |
Ho TH, Monzon FA, Hoang A, Tamboli P, Furge KA, Dykema K, Petillo D, Teh BT, Tannir NM, Hung MC, Jonasch E. Regulation of SETD2, a histone methyltransferase, in advanced clear cell renal cell carcinoma (ccRCC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 368. PMID 27968196 DOI: 10.1200/Jco.2012.30.5_Suppl.368 |
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| 2012 |
Hong S, Tsou PH, Chou CK, Yamaguchi H, Su CB, Hung MC, Kameoka J. Microfluidic three-dimensional hydrodynamic flow focusing for the rapid protein concentration analysis. Biomicrofluidics. 6: 24132. PMID 23785388 DOI: 10.1063/1.4730332 |
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Li L, Xie X, Luo J, Liu M, Xi S, Guo J, Kong Y, Wu M, Gao J, Xie Z, Tang J, Wang X, Wei W, Yang M, Hung MC, et al. Targeted expression of miR-34a using the T-VISA system suppresses breast cancer cell growth and invasion. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2326-34. PMID 23032974 DOI: 10.1038/Mt.2012.201 |
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Chen D, Sun Y, Wei Y, Zhang P, Rezaeian AH, Teruya-Feldstein J, Gupta S, Liang H, Lin HK, Hung MC, Ma L. LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nature Medicine. 18: 1511-7. PMID 23001183 DOI: 10.1038/Nm.2940 |
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Lee DF, Su J, Ang YS, Carvajal-Vergara X, Mulero-Navarro S, Pereira CF, Gingold J, Wang HL, Zhao R, Sevilla A, Darr H, Williamson AJ, Chang B, Niu X, Aguilo F, ... ... Hung MC, et al. Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell. 11: 179-94. PMID 22862944 DOI: 10.1016/J.Stem.2012.05.020 |
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Chen CT, Du Y, Yamaguchi H, Hsu JM, Kuo HP, Hortobagyi GN, Hung MC. Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer. Molecular Cancer Therapeutics. 11: 2212-21. PMID 22826466 DOI: 10.1158/1535-7163.MCT-12-0180 |
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Yu YL, Chou RH, Wu CH, Wang YN, Chang WJ, Tseng YJ, Chang WC, Lai CC, Lee HJ, Huo L, Chen CH, Hung MC. Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776. The Journal of Biological Chemistry. 287: 31015-26. PMID 22815474 DOI: 10.1074/jbc.M112.358077 |
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Xie X, Li L, Xiao X, Guo J, Kong Y, Wu M, Liu W, Gao G, Hsu JL, Wei W, Hung MC, Xie X. Targeted expression of BikDD eliminates breast cancer with virtually no toxicity in noninvasive imaging models. Molecular Cancer Therapeutics. 11: 1915-24. PMID 22752427 DOI: 10.1158/1535-7163.Mct-12-0191 |
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Yamaguchi H, Hsu JL, Hung MC. Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer. Frontiers in Oncology. 2: 15. PMID 22649777 DOI: 10.3389/fonc.2012.00015 |
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Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, et al. The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis. Cell. 149: 1098-111. PMID 22632973 DOI: 10.1016/J.Cell.2012.02.065 |
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Ouelaa-Benslama R, De Wever O, Hendrix A, Sabbah M, Lambein K, Land D, Prévost G, Bracke M, Hung MC, Larsen AK, Emami S, Gespach C. Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition International Journal of Oncology. 41: 189-200. PMID 22552300 DOI: 10.3892/ijo.2012.1457 |
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| 2012 |
Wang Y, Ding Q, Yen CJ, Xia W, Izzo JG, Lang JY, Li CW, Hsu JL, Miller SA, Wang X, Lee DF, Hsu JM, Huo L, Labaff AM, Liu D, ... ... Hung MC, et al. The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell. 21: 374-87. PMID 22439934 DOI: 10.1016/j.ccr.2011.12.028 |
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Yang WH, Lan HY, Huang CH, Tai SK, Tzeng CH, Kao SY, Wu KJ, Hung MC, Yang MH. RAC1 activation mediates Twist1-induced cancer cell migration. Nature Cell Biology. 14: 366-74. PMID 22407364 DOI: 10.1038/ncb2455 |
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| 2012 |
Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 21: 105-20. PMID 22264792 DOI: 10.1016/J.Ccr.2011.12.006 |
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| 2012 |
Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, ... Hung MC, et al. Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1 Cancer Research. 72: 1290-1300. PMID 22253230 DOI: 10.1158/0008-5472.CAN-11-3123 |
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| 2012 |
Zhao H, Ho PC, Lo YH, Espejo A, Bedford MT, Hung MC, Wang SC. Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer. Plos One. 7: e29416. PMID 22238610 DOI: 10.1371/Journal.Pone.0029416 |
0.396 |
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| 2012 |
Li X, Lu Y, Liang K, Hsu JM, Albarracin C, Mills GB, Hung MC, Fan Z. Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR. Oncogene. 31: 4372-83. PMID 22231447 DOI: 10.1038/Onc.2011.608 |
0.445 |
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| 2012 |
Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, ... Hung MC, et al. IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression. Molecular Cell. 45: 171-84. PMID 22196886 DOI: 10.1016/J.Molcel.2011.11.018 |
0.832 |
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| 2012 |
Ho TH, Monzon FA, Hoang A, Tamboli P, Furge KA, Dykema K, Petillo D, Teh BT, Tannir NM, Hung M, Jonasch E. Molecular characterization of SETD2, a histone methyltransferase, in clear cell renal cell carcinoma (ccRCC). Journal of Clinical Oncology. 30: 4624-4624. DOI: 10.1200/Jco.2012.30.15_Suppl.4624 |
0.331 |
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| 2012 |
Wang Y, Xia W, Lang J, Hsu J, Wang H, Ajani J, Hung M. Abstract 989: The crosstalk of mTOR/S6K1 and Hedgehog pathways Cancer Research. 72: 989-989. DOI: 10.1158/1538-7445.Am2012-989 |
0.415 |
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| 2012 |
Yang P, Hsieh C, Hung M, Kuo F, Huang Y, Lee J. Abstract 3465: The effect of ephrin-A1 on the resistance of photodynamic therapy in esophageal cancer cells Cancer Research. 72: 3465-3465. DOI: 10.1158/1538-7445.Am2012-3465 |
0.412 |
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| 2012 |
Khotskaya YB, Shen J, Chang S, Yu D, Steeg PS, Hung M. Abstract 3290: A novel model of breast cancer metastasis: Killing two birds with one stone Cancer Research. 72: 3290-3290. DOI: 10.1158/1538-7445.Am2012-3290 |
0.599 |
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| 2012 |
Zhao HJ, Ho P, Lo Y, Espejo A, Bedford MT, Hung M, Wang S. Abstract 3036: Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer Cancer Research. 72: 3036-3036. DOI: 10.1158/1538-7445.Am2012-3036 |
0.495 |
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| 2012 |
Du Y, Shen J, Hsu JL, Han Z, Wang Y, Yamaguchi H, Miller SA, Hung M. Abstract 1230: Syntaxin 6- and microtubule-mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR Cancer Research. 72: 1230-1230. DOI: 10.1158/1538-7445.Am2012-1230 |
0.39 |
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| 2012 |
Ho TH, Monzon FA, Hoang A, Tamboli P, Furge K, Dykema K, Petillo D, Teh BT, Tannir N, Jonasch E, Hung M. Abstract 1035: SETD2, a histone methyltransferase, is misregulated in advanced clear cell renal cell carcinoma (ccRCC) Cancer Research. 72: 1035-1035. DOI: 10.1158/1538-7445.Am2012-1035 |
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| 2011 |
Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, ... ... Hung MC, et al. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. The Journal of Clinical Investigation. 121: 4526-36. PMID 21985787 DOI: 10.1172/Jci45008 |
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| 2011 |
Su JL, Cheng X, Yamaguchi H, Chang YW, Hou CF, Lee DF, Ko HW, Hua KT, Wang YN, Hsiao M, Chen PB, Hsu JM, Bast RC, Hortobagyi GN, Hung MC. FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization. Cancer Research. 71: 6878-87. PMID 21911455 DOI: 10.1158/0008-5472.Can-11-0295 |
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| 2011 |
Lang JY, Hsu JL, Meric-Bernstam F, Chang CJ, Wang Q, Bao Y, Yamaguchi H, Xie X, Woodward WA, Yu D, Hortobagyi GN, Hung MC. BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment. Cancer Cell. 20: 341-56. PMID 21907925 DOI: 10.1016/J.Ccr.2011.07.017 |
0.604 |
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| 2011 |
Lee JC, Chou LC, Huang CH, Chung JG, Huang LJ, Lee KH, Hung MC, Way TD, Kuo SC. CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cells. European Journal of Pharmacology. 670: 96-104. PMID 21907193 DOI: 10.1016/j.ejphar.2011.08.006 |
0.341 |
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| 2011 |
Chen YJ, Huang WC, Wei YL, Hsu SC, Yuan P, Lin HY, Wistuba II, Lee JJ, Yen CJ, Su WC, Chang KY, Chang WC, Chou TC, Chou CK, Tsai CH, ... Hung MC, et al. Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. Plos One. 6: e21428. PMID 21731744 DOI: 10.1371/Journal.Pone.0021428 |
0.61 |
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| 2011 |
Jan CI, Yu CC, Hung MC, Harn HJ, Nieh S, Lee HS, Lou MA, Wu YC, Chen CY, Huang CY, Chen FN, Lo JF. Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients. The Journal of Pathology. 225: 424-37. PMID 21710689 DOI: 10.1002/path.2921 |
0.307 |
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| 2011 |
Tsai KS, Yang SH, Lei YP, Tsai CC, Chen HW, Hsu CY, Chen LL, Wang HW, Miller SA, Chiou SH, Hung MC, Hung SC. Mesenchymal stem cells promote formation of colorectal tumors in mice. Gastroenterology. 141: 1046-56. PMID 21699785 DOI: 10.1053/J.Gastro.2011.05.045 |
0.405 |
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| 2011 |
Banerjee A, Lang JY, Hung MC, Sengupta K, Banerjee SK, Baksi K, Banerjee DK. Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin. The Journal of Biological Chemistry. 286: 29127-38. PMID 21676868 DOI: 10.1074/jbc.M110.169771 |
0.303 |
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| 2011 |
Huang WC, Chen YJ, Li LY, Wei YL, Hsu SC, Tsai SL, Chiu PC, Huang WP, Wang YN, Chen CH, Chang WC, Chang WC, Chen AJ, Tsai CH, Hung MC. Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. The Journal of Biological Chemistry. 286: 20558-68. PMID 21487020 DOI: 10.1074/jbc.M111.240796 |
0.351 |
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| 2011 |
Yang JY, Hung MC. Deciphering the role of forkhead transcription factors in cancer therapy. Current Drug Targets. 12: 1284-90. PMID 21443462 |
0.836 |
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| 2011 |
Kim SJ, Kim JS, Park ES, Lee JS, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung MC, Fidler IJ. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia (New York, N.Y.). 13: 286-98. PMID 21390191 DOI: 10.1593/Neo.11112 |
0.318 |
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| 2011 |
Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu JL, Lee HH, Liu M, Chen CT, Yu D, Hung MC. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nature Cell Biology. 13: 317-23. PMID 21336307 DOI: 10.1038/Ncb2173 |
0.796 |
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| 2011 |
Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, Lin CY, Lee HJ, Wang YN, Liu M, Liao HW, Shi B, Lai CC, Bedford MT, Tsai CH, Hung MC. Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nature Cell Biology. 13: 174-81. PMID 21258366 DOI: 10.1038/Ncb2158 |
0.776 |
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| 2011 |
Zhao H, Lo YH, Ma L, Waltz SE, Gray JK, Hung MC, Wang SC. Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth. Molecular Cancer Therapeutics. 10: 29-36. PMID 21220489 DOI: 10.1158/1535-7163.MCT-10-0778 |
0.326 |
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| 2011 |
Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hsu JM, Hortobagyi GN, Hung MC. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling. Cancer Cell. 19: 86-100. PMID 21215703 DOI: 10.1016/J.Ccr.2010.10.035 |
0.836 |
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| 2011 |
Li LY, Dai HY, Yeh FL, Kan SF, Lang J, Hsu JL, Jeng LB, Chen YH, Sher YP, Lin WC, Hung MC. Targeted hepatocellular carcinoma proapoptotic BikDD gene therapy. Oncogene. 30: 1773-83. PMID 21151169 DOI: 10.1038/Onc.2010.558 |
0.382 |
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| 2011 |
Wei Y, Chen YH, Li LY, Lang J, Yeh SP, Shi B, Yang CC, Yang JY, Lin CY, Lai CC, Hung MC. CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nature Cell Biology. 13: 87-94. PMID 21131960 DOI: 10.1038/ncb2139 |
0.819 |
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| 2011 |
Rhodes LV, Short SP, Neel NF, Salvo VA, Zhu Y, Elliott S, Wei Y, Yu D, Sun M, Muir SE, Fonseca JP, Bratton MR, Segar C, Tilghman SL, Sobolik-Delmaire T, ... Hung MC, et al. Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer Research. 71: 603-13. PMID 21123450 DOI: 10.1158/0008-5472.Can-10-3185 |
0.616 |
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| 2011 |
Beyer I, Li Z, Persson J, Liu Y, van Rensburg R, Yumul R, Zhang XB, Hung MC, Lieber A. Controlled extracellular matrix degradation in breast cancer tumors improves therapy by trastuzumab. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 479-89. PMID 21081901 DOI: 10.1038/mt.2010.256 |
0.307 |
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| 2011 |
Zhu QS, Rosenblatt K, Huang KL, Lahat G, Brobey R, Bolshakov S, Nguyen T, Ding Z, Belousov R, Bill K, Luo X, Lazar A, Dicker A, Mills GB, Hung MC, et al. Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene. 30: 457-70. PMID 20856200 DOI: 10.1038/Onc.2010.421 |
0.485 |
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| 2011 |
Li L, Chen H, Hsieh Y, Wang Y, Chu H, Tsai C, Hung M. Abstract A57: The novel function of nuclear ErbB-2 in regulating transcription of rRNA genes Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A57 |
0.36 |
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| 2011 |
Chang C, Hung M. Abstract 976: Hypoxic microenvironment promotes breast cancer stem cells through regulation of Polycomb protein expression Cancer Research. 71: 976-976. DOI: 10.1158/1538-7445.Am2011-976 |
0.509 |
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| 2011 |
Yamaguchi H, Hsu J, Ko H, Wang Y, Chang S, Hung M. Abstract 721: Putative molecular mechanism contributing AZD6244 resistance in lung cancer Cancer Research. 71: 721-721. DOI: 10.1158/1538-7445.Am2011-721 |
0.306 |
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| 2011 |
Chao C, Chang C, Xia W, Yang J, Xiong Y, Li C, Hung M. Abstract 4710: p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulation of miRNAs Cancer Research. 71: 4710-4710. DOI: 10.1158/1538-7445.Am2011-4710 |
0.809 |
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| 2011 |
Wang Y, Yamaguchi H, Huo L, Du Y, Lee H, Lee H, Wang H, Hsu J, Hung M. Abstract 4051: EGF receptor trafficking from the cell surface to the nucleus through the Golgi, ER, and nuclear envelope Cancer Research. 71: 4051-4051. DOI: 10.1158/1538-7445.Am2011-4051 |
0.336 |
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| 2011 |
Khotskaya YB, Beck BH, Hurst DR, Hung M, Welch DR. Abstract 1438: Breast cancer metastasis suppressor 1 (BRMS1) suppresses attachment and spreading of breast cancer cells on 2D and 3D extracellular matrix components by altering focal adhesion-associated signaling Cancer Research. 71: 1438-1438. DOI: 10.1158/1538-7445.Am2011-1438 |
0.446 |
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| 2011 |
Huo L, Wang Y, Xia W, Hsu S, Lai C, Li L, Chang W, Wang Y, Hsu M, Yu Y, Huang T, Ding Q, Chen C, Tsai C, Hung M. Abstract 1086: RHA plays an important role in EGFR-mediated gene transcription in cancer cells Cancer Research. 71: 1086-1086. DOI: 10.1158/1538-7445.Am2011-1086 |
0.436 |
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| 2011 |
Adkins F, Kim W, Akcakanat A, Singh G, Hung M, Meric-Bernstam F. Differential Regulation Of Tumor Suppressor PDCD4 Expression By Rapamycin Journal of Surgical Research. 165: 178. DOI: 10.1016/J.Jss.2010.11.762 |
0.356 |
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| 2010 |
Hong S, Wang YN, Yamaguchi H, Sreenivasappa H, Chou CK, Tsou PH, Hung MC, Kameoka J. MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS). Journal of Biomaterials and Nanobiotechnology. 1: 31-36. PMID 21804949 DOI: 10.4236/Jbnb.2010.11004 |
0.563 |
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| 2010 |
Jin Q, Yuan LX, Boulbes D, Baek JM, Wang YN, Gomez-Cabello D, Hawke DH, Yeung SC, Lee MH, Hortobagyi GN, Hung MC, Esteva FJ. Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells. Breast Cancer Research : Bcr. 12: R96. PMID 21080941 DOI: 10.1186/bcr2777 |
0.395 |
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| 2010 |
Liang K, Esteva FJ, Albarracin C, Stemke-Hale K, Lu Y, Bianchini G, Yang CY, Li Y, Li X, Chen CT, Mills GB, Hortobagyi GN, Mendelsohn J, Hung MC, Fan Z. Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation. Cancer Cell. 18: 423-35. PMID 21075308 DOI: 10.1016/j.ccr.2010.10.025 |
0.364 |
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| 2010 |
Cheng X, Xia W, Yang JY, Hsu JL, Chou CK, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis. Biochemical and Biophysical Research Communications. 403: 103-7. PMID 21040707 DOI: 10.1016/J.Bbrc.2010.10.126 |
0.814 |
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| 2010 |
Chou CK, Jing N, Yamaguchi H, Tsou PH, Lee HH, Chen CT, Wang YN, Hong S, Su C, Kameoka J, Hung MC. Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device. The Analyst. 135: 2907-12. PMID 20877860 DOI: 10.1039/C0An00229A |
0.487 |
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| 2010 |
Luyimbazi D, Akcakanat A, McAuliffe PF, Zhang L, Singh G, Gonzalez-Angulo AM, Chen H, Do KA, Zheng Y, Hung MC, Mills GB, Meric-Bernstam F. Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer. Molecular Cancer Therapeutics. 9: 2770-84. PMID 20876744 DOI: 10.1158/1535-7163.MCT-09-0980 |
0.384 |
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| 2010 |
Cheng X, Xia W, Yang JY, Hsu JL, Lang JY, Chou CK, Du Y, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis. Cancer Research. 70: 7684-9. PMID 20841468 DOI: 10.1158/0008-5472.Can-09-3231 |
0.822 |
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| 2010 |
Huo L, Wang YN, Xia W, Hsu SC, Lai CC, Li LY, Chang WC, Wang Y, Hsu MC, Yu YL, Huang TH, Ding Q, Chen CH, Tsai CH, Hung MC. RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 107: 16125-30. PMID 20802156 DOI: 10.1073/Pnas.1000743107 |
0.393 |
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| 2010 |
Yamaguchi H, Chen CT, Chou CK, Pal A, Bornmann W, Hortobagyi GN, Hung MC. Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation Oncogene. 29: 5619-5629. PMID 20676141 DOI: 10.1038/Onc.2010.295 |
0.626 |
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| 2010 |
Su JL, Chen PB, Chen YH, Chen SC, Chang YW, Jan YH, Cheng X, Hsiao M, Hung MC. Downregulation of microRNA miR-520h by E1A contributes to anticancer activity. Cancer Research. 70: 5096-108. PMID 20501832 DOI: 10.1158/0008-5472.Can-09-4148 |
0.627 |
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| 2010 |
Chou CK, Jing N, Yamaguchi H, Tsou PH, Lee HH, Chen CT, Wang YN, Hong S, Su C, Kameoka J, Hung MC. High speed digital protein interaction analysis using microfluidic single molecule detection system. Lab On a Chip. 10: 1793-8. PMID 20498894 DOI: 10.1039/C002937H |
0.51 |
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| 2010 |
Yang JY, Chang CJ, Xia W, Wang Y, Wong KK, Engelman JA, Du Y, Andreeff M, Hortobagyi GN, Hung MC. Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer. Cancer Research. 70: 4709-18. PMID 20484037 DOI: 10.1158/0008-5472.Can-09-4524 |
0.831 |
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| 2010 |
Yang G, Chang B, Yang F, Guo X, Cai KQ, Xiao XS, Wang H, Sen S, Hung MC, Mills GB, Chang S, Multani AS, Mercado-Uribe I, Liu J. Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3171-81. PMID 20423983 DOI: 10.1158/1078-0432.Ccr-09-3171 |
0.478 |
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| 2010 |
Lahat G, Zhu QS, Huang KL, Wang S, Bolshakov S, Liu J, Torres K, Langley RR, Lazar AJ, Hung MC, Lev D. Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies. Plos One. 5: e10105. PMID 20419128 DOI: 10.1371/Journal.Pone.0010105 |
0.43 |
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| 2010 |
Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nature Cell Biology. 12: 457-67. PMID 20383141 DOI: 10.1038/Ncb2047 |
0.345 |
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| 2010 |
Zhang W, Konopleva M, Burks JK, Dywer KC, Schober WD, Yang JY, McQueen TJ, Hung MC, Andreeff M. Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim. Cancer Research. 70: 2424-34. PMID 20215498 DOI: 10.1158/0008-5472.Can-09-0878 |
0.816 |
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| 2010 |
Kuo HP, Hung MC. Arrest-defective-1 protein (ARD1): tumor suppressor or oncoprotein? American Journal of Translational Research. 2: 56-64. PMID 20182582 |
0.72 |
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| 2010 |
Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, ... Hung MC, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling. 3: ra9. PMID 20145209 DOI: 10.1126/Scisignal.2000590 |
0.828 |
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| 2010 |
Esteva FJ, Yu D, Hung MC, Hortobagyi GN. Molecular predictors of response to trastuzumab and lapatinib in breast cancer. Nature Reviews. Clinical Oncology. 7: 98-107. PMID 20027191 DOI: 10.1038/Nrclinonc.2009.216 |
0.579 |
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| 2010 |
Jiralerspong S, Liu S, Palla SL, Mills GB, Hung M, Hortobagyi GN, Gonzalez-Angulo AM. Correlation of Snail expression and survival in patients with early-stage triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 28: 10525-10525. DOI: 10.1200/Jco.2010.28.15_Suppl.10525 |
0.409 |
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| 2010 |
Yang P, Hung M, Wang Y, Tung E, Lee Y, Lee J. Abstract 499: EGFR expression correlates with response to photodynamic therapy in esophageal cancer cells Cancer Research. 70: 499-499. DOI: 10.1158/1538-7445.Am10-499 |
0.427 |
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| 2010 |
Chou C, Jing N, Yamaguchi H, Tsou P, Kameoka J, Hung M. Abstract 4017: Identifying Protein-Protein Interactions in Single Protein Complex level by Microchannel Device Cancer Research. 70: 4017-4017. DOI: 10.1158/1538-7445.Am10-4017 |
0.593 |
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| 2010 |
Kim SJ, Kim J, Park ES, Lee J, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung M, Fidler IJ. Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy Cancer Research. 70: 3428-3428. DOI: 10.1158/1538-7445.Am10-3428 |
0.434 |
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| 2010 |
Hsu S, Hung M. Abstract 263: p38 MAPK is required for EGFR nuclear translocation Cancer Research. 70: 263-263. DOI: 10.1158/1538-7445.Am10-263 |
0.39 |
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| 2010 |
Hong S, Sreenivasappa H, Yamaguchi H, Wang Y, Chou C, Hung M, Kameoka J. Raster Image Correlation Spectroscopy for Anti-Cancer Drug Screening Based on the Identification of Molecular Dynamics Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2185 |
0.605 |
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| 2009 |
Zhang D, LaFortune TA, Krishnamurthy S, Esteva FJ, Cristofanilli M, Liu P, Lucci A, Singh B, Hung MC, Hortobagyi GN, Ueno NT. Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer Clinical Cancer Research. 15: 6639-6648. PMID 19825949 DOI: 10.1158/1078-0432.CCR-09-0951 |
0.368 |
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| 2009 |
Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, ... ... Hung MC, et al. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Molecular Cell. 36: 131-40. PMID 19818716 DOI: 10.1016/J.Molcel.2009.07.025 |
0.813 |
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| 2009 |
Kuo HP, Lee DF, Xia W, Wei Y, Hung MC. TNFalpha induces HIF-1alpha expression through activation of IKKbeta. Biochemical and Biophysical Research Communications. 389: 640-4. PMID 19766100 DOI: 10.1016/j.bbrc.2009.09.042 |
0.793 |
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| 2009 |
Lu J, Guo H, Treekitkarnmongkol W, Li P, Zhang J, Shi B, Ling C, Zhou X, Chen T, Chiao PJ, Feng X, Seewaldt VL, Muller WJ, Sahin A, Hung MC, et al. 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell. 16: 195-207. PMID 19732720 DOI: 10.1016/J.Ccr.2009.08.010 |
0.665 |
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| 2009 |
Jiralerspong S, Gonzalez-Angulo AM, Hung MC. Expanding the arsenal: metformin for the treatment of triple-negative breast cancer? Cell Cycle (Georgetown, Tex.). 8: 2681. PMID 19717981 DOI: 10.4161/Cc.8.17.9502 |
0.387 |
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| 2009 |
Kuo HP, Lee DF, Xia W, Lai CC, Li LY, Hung MC. Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation. Biochemical and Biophysical Research Communications. 389: 156-61. PMID 19716809 DOI: 10.1016/j.bbrc.2009.08.127 |
0.823 |
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| 2009 |
Melnikova VO, Balasubramanian K, Villares GJ, Dobroff AS, Zigler M, Wang H, Petersson F, Price JE, Schroit A, Prieto VG, Hung MC, Bar-Eli M. Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis. The Journal of Biological Chemistry. 284: 28845-55. PMID 19703903 DOI: 10.1074/Jbc.M109.042150 |
0.307 |
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| 2009 |
Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC, Hung MC. A novel hTERT promoter-driven E1A therapeutic for ovarian cancer. Molecular Cancer Therapeutics. 8: 2375-82. PMID 19671744 DOI: 10.1158/1535-7163.Mct-09-0056 |
0.307 |
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| 2009 |
Chou CK, Lee DF, Sun HL, Li LY, Lin CY, Huang WC, Hsu JM, Kuo HP, Yamaguchi H, Wang YN, Liu M, Wu HY, Liao PC, Yen CJ, Hung MC. The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. Molecular Carcinogenesis. 48: 1048-58. PMID 19526459 DOI: 10.1002/Mc.20557 |
0.818 |
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| 2009 |
Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung MC, Hortobagyi GN, Gonzalez-Angulo AM. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 3297-302. PMID 19487376 DOI: 10.1200/Jco.2009.19.6410 |
0.327 |
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| 2009 |
Liao Y, Wei Y, Zhou X, Yang JY, Dai C, Chen YJ, Agarwal NK, Sarbassov D, Shi D, Yu D, Hung MC. Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation. Oncogene. 28: 2436-45. PMID 19448664 DOI: 10.1038/Onc.2009.98 |
0.8 |
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| 2009 |
Cheng X, Hung MC. Regulation of breast cancer metastasis by atypical chemokine receptors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2951-3. PMID 19383808 DOI: 10.1158/1078-0432.CCR-09-0141 |
0.646 |
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| 2009 |
Hawthorne VS, Huang WC, Neal CL, Tseng LM, Hung MC, Yu D. ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells. Molecular Cancer Research : McR. 7: 592-600. PMID 19372587 DOI: 10.1158/1541-7786.Mcr-08-0316 |
0.84 |
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| 2009 |
Neal CL, Yao J, Yang W, Zhou X, Nguyen NT, Lu J, Danes CG, Guo H, Lan KH, Ensor J, Hittelman W, Hung MC, Yu D. 14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival. Cancer Research. 69: 3425-32. PMID 19318578 DOI: 10.1158/0008-5472.Can-08-2765 |
0.829 |
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| 2009 |
Huang WC, Hung MC. Induction of Akt activity by chemotherapy confers acquired resistance. Journal of the Formosan Medical Association = Taiwan Yi Zhi. 108: 180-94. PMID 19293033 DOI: 10.1016/S0929-6646(09)60051-6 |
0.317 |
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| 2009 |
Hung MC, Mills GB, Yu D. Oxygen sensor boosts growth factor signaling. Nature Medicine. 15: 246-7. PMID 19265822 DOI: 10.1038/Nm0309-246 |
0.504 |
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| 2009 |
Song S, Mazurek N, Liu C, Sun Y, Ding QQ, Liu K, Hung MC, Bresalier RS. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Research. 69: 1343-9. PMID 19190323 DOI: 10.1158/0008-5472.Can-08-4153 |
0.377 |
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| 2009 |
Yang JY, Hung MC. A new fork for clinical application: targeting forkhead transcription factors in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 752-7. PMID 19188143 DOI: 10.1158/1078-0432.CCR-08-0124 |
0.836 |
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| 2009 |
Xia W, Wei Y, Du Y, Liu J, Chang B, Yu YL, Huo LF, Miller S, Hung MC. Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer. Molecular Carcinogenesis. 48: 610-7. PMID 19058255 DOI: 10.1002/Mc.20504 |
0.398 |
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| 2009 |
Ueno N, Kazansky A, LaFortune T, Lucci A, Krishnamurthy S, Hung M, Hortobagyi G, Woodward W, Reuben J, Robertson F, Cristofanilli M, Zhang D. Suppression of mesenchymal phenotype in inflammatory breast cancer by EGFR tyrosine kinase inhibitor erlotinib: a novel approach to suppressing metastasis. Cancer Research. 69: 2042. DOI: 10.1158/0008-5472.Sabcs-2042 |
0.426 |
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| 2009 |
Sher Y, Tzeng T, Kan S, Hsu J, Xie X, Han Z, Lin W, Li L, Hung M. Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival Oncogene. 28: 3286-3295. DOI: 10.1038/Onc.2009.187 |
0.437 |
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| 2008 |
Tsou PH, Chou CK, Saldana S, Hung MC, Kameoka J. The fabrication and testing of electrospun silica nanofiber membranes for the detection of proteins. Nanotechnology. 19: 445714. PMID 19081800 DOI: 10.1088/0957-4484/19/44/445714 |
0.51 |
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| 2008 |
Lee C, Dhillon J, Wang MY, Gao Y, Hu K, Park E, Astanehe A, Hung MC, Eirew P, Eaves CJ, Dunn SE. Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice. Cancer Research. 68: 8661-6. PMID 18974106 DOI: 10.1158/0008-5472.Can-08-1082 |
0.431 |
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| 2008 |
Lee DF, Kuo HP, Chen CT, Wei Y, Chou CK, Hung JY, Yen CJ, Hung MC. IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance. International Journal of Molecular Medicine. 22: 633-8. PMID 18949383 DOI: 10.3892/ijmm_00000065 |
0.789 |
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| 2008 |
Wang RH, Zheng Y, Kim HS, Xu X, Cao L, Luhasen T, Lee MH, Xiao C, Vassilopoulos A, Chen W, Gardner K, Man YG, Hung MC, Finkel T, Deng CX. Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. Molecular Cell. 32: 11-20. PMID 18851829 DOI: 10.1016/J.Molcel.2008.09.011 |
0.372 |
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Tan M, Jing T, Lan KH, Neal CL, Li P, Lee S, Fang D, Nagata Y, Liu J, Arlinghaus R, Hung MC, Yu D. Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Molecular Cell. 9: 993-1004. PMID 12049736 DOI: 10.1016/S1097-2765(02)00510-5 |
0.824 |
|
| 2002 |
Wang SC, Shao R, Pao AY, Zhang S, Hung MC, Su LK. Inhibition of cancer cell growth by BRCA2. Cancer Research. 62: 1311-4. PMID 11888897 |
0.37 |
|
| 2002 |
Meric F, Lee WP, Sahin A, Zhang H, Kung HJ, Hung MC. Expression profile of tyrosine kinases in breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 361-7. PMID 11839650 |
0.656 |
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| 2002 |
Lee WP, Wen Y, Varnum B, Hung MC. Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis. Oncogene. 21: 329-36. PMID 11821945 DOI: 10.1038/sj.onc.1205066 |
0.742 |
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| 2002 |
Zou Y, Peng H, Zhou B, Wen Y, Wang SC, Tsai EM, Hung MC. Systemic tumor suppression by the proapoptotic gene bik. Cancer Research. 62: 8-12. PMID 11782349 |
0.626 |
|
| 2002 |
Hung M, Hortobagyi GN, Ueno NT. Development of clinical trial of E1A gene therapy targeting HER-2/neu-overexpressing breast and ovarian cancer. Advances in Experimental Medicine and Biology. 465: 171-180. PMID 10810625 DOI: 10.1007/0-306-46817-4_16 |
0.367 |
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| 2002 |
Bourguignon L, Lan K, Singleton P, Lin S, Yu D, Hung M. Localizing the EGF receptor - Reply Nature Cell Biology. 4: E22-E23. DOI: 10.1038/Ncb0202-E22B |
0.724 |
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| 2001 |
Hung M, Yan D, Zhang S. E1A-Mediated Gene Therapy. Methods in Molecular Medicine. 39: 775-782. PMID 21340839 DOI: 10.1385/1-59259-071-3:775 |
0.426 |
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| 2001 |
Meisler A, Hortobagyi GN, Ueno N, Hung M. E1A Is an Oncogene and May Immortalize Normal Cells, Especially in Combination With Other Oncoproteins Journal of Clinical Oncology. 19: 4183-4184. PMID 11689591 DOI: 10.1200/Jco.2001.19.21.4183 |
0.334 |
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| 2001 |
Wen Y, Yan DH, Wang B, Spohn B, Ding Y, Shao R, Zou Y, Xie K, Hung MC. p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models. Cancer Research. 61: 7142-7. PMID 11585747 |
0.638 |
|
| 2001 |
Lin SY, Makino K, Xia W, Matin A, Wen Y, Kwong KY, Bourguignon L, Hung MC. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nature Cell Biology. 3: 802-8. PMID 11533659 DOI: 10.1038/Ncb0901-802 |
0.569 |
|
| 2001 |
Hortobagyi GN, Ueno NT, Xia W, Zhang S, Wolf JK, Putnam JB, Weiden PL, Willey JS, Carey M, Branham DL, Payne JY, Tucker SD, Bartholomeusz C, Kilbourn RG, De Jager RL, ... ... Hung MC, et al. Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: A phase I clinical trial Journal of Clinical Oncology. 19: 3422-3433. PMID 11454891 DOI: 10.1200/Jco.2001.19.14.3422 |
0.42 |
|
| 2001 |
Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nature Cell Biology. 3: 245-52. PMID 11231573 DOI: 10.1038/35060032 |
0.44 |
|
| 2000 |
Hung M, Wang S. Suppressing HER2/neu-mediated cell transformation by transcriptional repressors. Breast Disease. 11: 133-144. PMID 15687599 DOI: 10.3233/Bd-1999-11112 |
0.496 |
|
| 2000 |
Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC. HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Research. 60: 6841-5. PMID 11156376 |
0.602 |
|
| 2000 |
Meric F, Liao Y, Lee WP, Pollock RE, Hung MC. Adenovirus 5 early region 1A does not induce expression of the ewing sarcoma fusion product EWS-FLI1 in breast and ovarian cancer cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 3832-6. PMID 11051226 |
0.636 |
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| 2000 |
Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R. Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. The Journal of Biological Chemistry. 275: 36238-44. PMID 10945974 DOI: 10.1074/Jbc.M002138200 |
0.491 |
|
| 2000 |
Yang H, Zhou BP, Hung M, Lee M. Oncogenic signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27. Journal of Biological Chemistry. 275: 24735-24739. PMID 10859299 DOI: 10.1074/Jbc.C000147200 |
0.449 |
|
| 2000 |
Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG, Hung MC. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 97: 4262-6. PMID 10759547 DOI: 10.1073/Pnas.060025397 |
0.62 |
|
| 2000 |
Zhou BP, Hu MC, Miller SA, Yu Z, Xia W, Lin SY, Hung MC. HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway. The Journal of Biological Chemistry. 275: 8027-31. PMID 10713122 DOI: 10.1074/JBC.275.11.8027 |
0.707 |
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| 2000 |
Xing X, Wang SC, Xia W, Zou Y, Shao R, Kwong KY, Yu Z, Zhang S, Miller S, Huang L, Hung MC. The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis. Nature Medicine. 6: 189-95. PMID 10655108 DOI: 10.1038/72294 |
0.703 |
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| 2000 |
Wen Y, Yan DH, Spohn B, Deng J, Lin SY, Hung MC. Tumor suppression and sensitization to tumor necrosis factor alpha-induced apoptosis by an interferon-inducible protein, p202, in breast cancer cells. Cancer Research. 60: 42-6. PMID 10646849 |
0.652 |
|
| 1999 |
Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Siminovitch K, Mills GB. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene. 18: 7034-45. PMID 10597304 DOI: 10.1038/Sj.Onc.1203183 |
0.465 |
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| 1999 |
Lee WP, Liao Y, Robinson D, Kung HJ, Liu ET, Hung MC. Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity. Molecular and Cellular Biology. 19: 8075-82. PMID 10567533 DOI: 10.1128/Mcb.19.12.8075 |
0.646 |
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| 1999 |
Hung MC, Lau YK. Basic science of HER-2/neu: A review Seminars in Oncology. 26: 51-59. PMID 10482194 |
0.433 |
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| 1999 |
Zhang L, Lau YK, Xia W, Hortobagyi GN, Hung MC. Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 343-53. PMID 10037184 |
0.39 |
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| 1999 |
Yan DH, Wen Y, Spohn B, Choubey D, Gutterman JU, Hung MC. Reduced growth rate and transformation phenotype of the prostate cancer cells by an interferon-inducible protein, p202. Oncogene. 18: 807-11. PMID 9989832 DOI: 10.1038/Sj.Onc.1202369 |
0.595 |
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| 1998 |
Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, Hung MC. Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Molecular Cell. 2: 581-91. PMID 9844631 DOI: 10.1016/S1097-2765(00)80157-4 |
0.83 |
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| 1998 |
Zhang L, Lau YK, Xi L, Hong RL, Kim DS, Chen CF, Hortobagyi GN, Chang C, Hung MC. Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties. Oncogene. 16: 2855-63. PMID 9671406 DOI: 10.1038/sj.onc.1201813 |
0.321 |
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| 1997 |
Ueno NT, Yu D, Hung MC. Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A. Oncogene. 15: 953-60. PMID 9285690 DOI: 10.1038/Sj.Onc.1201250 |
0.653 |
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| 1997 |
Gershenson DM, Baker VV, Price JE, Hung MC, El-Naggar AK, Tortolero-Luna G, Silva EG. Molecular profile of advanced-stage transitional cell carcinoma of the ovary. American Journal of Obstetrics and Gynecology. 177: 120-5. PMID 9240594 DOI: 10.1016/S0002-9378(97)70449-6 |
0.312 |
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| 1994 |
Miller S, Suen T, Sexton T, Hung M. Mechanisms of deregulated her2/neu expression in breast-cancer cell-lines. International Journal of Oncology. 4: 599-608. PMID 21566965 |
0.329 |
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| 1991 |
Yu D, Scorsone K, Hung M. Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene Molecular and Cellular Biology. 11: 1745-1750. PMID 1671710 DOI: 10.1128/Mcb.11.3.1745 |
0.305 |
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| 1990 |
Yu UA, Suen TC, Yan DH, Chang LS, Hung MC. Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products Proceedings of the National Academy of Sciences of the United States of America. 87: 4499-4503. PMID 1972274 DOI: 10.1073/Pnas.87.12.4499 |
0.358 |
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| 1989 |
Hung M, Yan D, Zhao X. Amplification of the proto-neu oncogene facilitates oncogenic activation by a single point mutation. Proceedings of the National Academy of Sciences of the United States of America. 86: 2545-2548. PMID 2565034 DOI: 10.1073/Pnas.86.8.2545 |
0.362 |
|
| 1986 |
Bargmann CI, Hung MC, Weinberg RA. The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature. 319: 226-30. PMID 3945311 DOI: 10.1038/319226A0 |
0.625 |
|
| 1986 |
Hung MC, Schechter AL, Chevray PYM, Stern DF, Weinberg RA. Molecular cloning of the neu gene: Absence of gross structural alteration in oncogenic alleles Proceedings of the National Academy of Sciences of the United States of America. 83: 261-264. PMID 3001730 DOI: 10.1073/Pnas.83.2.261 |
0.617 |
|
| 1986 |
Bargmann CI, Hung MC, Weinberg RA. Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 45: 649-57. PMID 2871941 DOI: 10.1016/0092-8674(86)90779-8 |
0.61 |
|
| 1985 |
Shepherd B, Garabedian MJ, Hung MC, Wensink PC. Developmental control of Drosophila yolk protein 1 gene by cis-acting DNA elements. Cold Spring Harbor Symposia On Quantitative Biology. 50: 521-6. PMID 3938365 |
0.722 |
|
| 1985 |
Garabedian MJ, Hung MC, Wensink PC. Independent control elements that determine yolk protein gene expression in alternative Drosophila tissues. Proceedings of the National Academy of Sciences of the United States of America. 82: 1396-400. PMID 3919395 DOI: 10.1073/Pnas.82.5.1396 |
0.721 |
|
| 1985 |
Schechter AL, Hung MC, Vaidyanathan L, Weinberg RA, Yang-Feng TL, Francke U, Ullrich A, Coussens L. The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor Science. 229: 976-978. PMID 2992090 DOI: 10.1126/Science.2992090 |
0.429 |
|
| 1984 |
Hung MC, Wensink PC. Different restriction enzyme-generated sticky DNA ends can be joined in vitro. Nucleic Acids Research. 12: 1863-74. PMID 6199744 DOI: 10.1093/nar/12.4.1863 |
0.605 |
|
| 1983 |
Hung MC, Wensink PC. Sequence and structure conservation in yolk proteins and their genes. Journal of Molecular Biology. 164: 481-92. PMID 6405043 DOI: 10.1016/0022-2836(83)90046-3 |
0.63 |
|
| 1982 |
Hung MC, Barnett T, Woolford C, Wensink PC. Transcript maps of Drosophila yolk protein genes. Journal of Molecular Biology. 154: 581-602. PMID 6283091 DOI: 10.1016/S0022-2836(82)80016-8 |
0.63 |
|
| 1981 |
Hung MC, Wensink PC. The sequence of the Drosophila melanogaster gene for yolk protein 1. Nucleic Acids Research. 9: 6407-19. PMID 6275360 DOI: 10.1093/nar/9.23.6407 |
0.624 |
|
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