Richard Carthew - Publications

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86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bernasek SM, Peláez N, Carthew RW, Bagheri N, Amaral LAN. Fly-QMA: Automated analysis of mosaic imaginal discs in Drosophila. Plos Computational Biology. 16: e1007406. PMID 32126077 DOI: 10.1371/Journal.Pcbi.1007406  0.56
2019 Agbu P, Cassidy JJ, Braverman J, Jacobson A, Carthew RW. MicroRNA miR-7 regulates secretion of insulin-like peptides. Endocrinology. PMID 31875904 DOI: 10.1210/endocr/bqz040  0.56
2019 Cassidy JJ, Bernasek SM, Bakker R, Giri R, Peláez N, Eder B, Bobrowska A, Bagheri N, Nunes Amaral LA, Carthew RW. Repressive Gene Regulation Synchronizes Development with Cellular Metabolism. Cell. PMID 31353220 DOI: 10.1016/J.Cell.2019.06.023  0.56
2016 Kim S, Cassidy JJ, Yang B, Carthew RW, Hilgenfeldt S. Hexagonal Patterning of the Insect Compound Eye: Facet Area Variation, Defects, and Disorder. Biophysical Journal. 111: 2735-2746. PMID 28002749 DOI: 10.1016/J.Bpj.2016.11.004  0.56
2016 Carthew RW, Agbu P, Giri R. MicroRNA function in Drosophila melanogaster. Seminars in Cell & Developmental Biology. PMID 27000418 DOI: 10.1016/j.semcdb.2016.03.015  1
2015 Cassidy JJ, Straughn AJ, Carthew RW. Differential Masking of Natural Genetic Variation by miR-9a in Drosophila. Genetics. PMID 26614743 DOI: 10.1534/genetics.115.183822  0.56
2015 Peláez N, Gavalda-Miralles A, Wang B, Navarro HT, Gudjonson H, Rebay I, Dinner AR, Katsaggelos AK, Amaral LA, Carthew RW. Dynamics and heterogeneity of a fate determinant during transition towards cell differentiation. Elife. 4. PMID 26583752 DOI: 10.7554/Elife.08924  0.32
2014 Posadas DM, Carthew RW. MicroRNAs and their roles in developmental canalization. Current Opinion in Genetics & Development. 27: 1-6. PMID 24791686 DOI: 10.1016/j.gde.2014.03.005  1
2014 Giri R, Carthew RW. microRNAs suppress cellular phenotypic heterogeneity. Cell Cycle (Georgetown, Tex.). 13: 1517-8. PMID 24769868 DOI: 10.4161/cc.29013  1
2014 Boisclair Lachance JF, Peláez N, Cassidy JJ, Webber JL, Rebay I, Carthew RW. A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling. Developmental Biology. 385: 263-78. PMID 24240101 DOI: 10.1016/J.Ydbio.2013.11.002  1
2013 Qi J, Wang B, Pelaez N, Rebay I, Carthew RW, Katsaggelos AK, Nunes Amaral LA. Drosophila Eye Nuclei Segmentation Based on Graph Cut and Convex Shape Prior. International Conference On Signal Processing Proceedings. International Conference On Signal Processing. 670-674. PMID 25089515 DOI: 10.1109/ICIP.2013.6738138  1
2013 Cassidy JJ, Jha AR, Posadas DM, Giri R, Venken KJ, Ji J, Jiang H, Bellen HJ, White KP, Carthew RW. miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor. Cell. 155: 1556-67. PMID 24360277 DOI: 10.1016/J.Cell.2013.10.057  1
2013 Wu PH, Isaji M, Carthew RW. Functionally diverse microRNA effector complexes are regulated by extracellular signaling. Molecular Cell. 52: 113-23. PMID 24055343 DOI: 10.1016/j.molcel.2013.08.023  1
2013 Marques JT, Wang JP, Wang X, de Oliveira KP, Gao C, Aguiar ER, Jafari N, Carthew RW. Functional specialization of the small interfering RNA pathway in response to virus infection. Plos Pathogens. 9: e1003579. PMID 24009507 DOI: 10.1371/journal.ppat.1003579  1
2013 Webber JL, Zhang J, Cote L, Vivekanand P, Ni X, Zhou J, Nègre N, Carthew RW, White KP, Rebay I. The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan. Genetics. 193: 633-49. PMID 23172856 DOI: 10.1534/Genetics.112.146647  1
2012 Nakahara KS, Masuta C, Yamada S, Shimura H, Kashihara Y, Wada TS, Meguro A, Goto K, Tadamura K, Sueda K, Sekiguchi T, Shao J, Itchoda N, Matsumura T, Igarashi M, ... ... Carthew RW, et al. Tobacco calmodulin-like protein provides secondary defense by binding to and directing degradation of virus RNA silencing suppressors. Proceedings of the National Academy of Sciences of the United States of America. 109: 10113-8. PMID 22665793 DOI: 10.1073/pnas.1201628109  1
2012 Pressman S, Reinke CA, Wang X, Carthew RW. A Systematic Genetic Screen to Dissect the MicroRNA Pathway in Drosophila. G3 (Bethesda, Md.). 2: 437-48. PMID 22540035 DOI: 10.1534/g3.112.002030  1
2012 Peláez N, Carthew RW. Biological robustness and the role of microRNAs: a network perspective. Current Topics in Developmental Biology. 99: 237-55. PMID 22365741 DOI: 10.1016/B978-0-12-387038-4.00009-4  1
2011 Gemp IM, Carthew RW, Hilgenfeldt S. Cadherin-dependent cell morphology in an epithelium: constructing a quantitative dynamical model. Plos Computational Biology. 7: e1002115. PMID 21814505 DOI: 10.1371/Journal.Pcbi.1002115  1
2011 Harris DA, Kim K, Nakahara K, Vásquez-Doorman C, Carthew RW. Cargo sorting to lysosome-related organelles regulates siRNA-mediated gene silencing. The Journal of Cell Biology. 194: 77-87. PMID 21746852 DOI: 10.1083/jcb.201102021  1
2010 Lu J, Shen Y, Carthew RW, Wang SM, Wu CI. Reply to evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nature Genetics. 42: 9-10. PMID 25067898 DOI: 10.1038/Ng0110-9  1
2010 Marques JT, Kim K, Wu PH, Alleyne TM, Jafari N, Carthew RW. Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila. Nature Structural & Molecular Biology. 17: 24-30. PMID 20037596 DOI: 10.1038/nsmb.1735  1
2009 Lucchetta EM, Carthew RW, Ismagilov RF. The endo-siRNA pathway is essential for robust development of the Drosophila embryo. Plos One. 4: e7576. PMID 19851503 DOI: 10.1371/Journal.Pone.0007576  1
2009 Lee YS, Pressman S, Andress AP, Kim K, White JL, Cassidy JJ, Li X, Lubell K, Lim do H, Cho IS, Nakahara K, Preall JB, Bellare P, Sontheimer EJ, Carthew RW. Silencing by small RNAs is linked to endosomal trafficking. Nature Cell Biology. 11: 1150-6. PMID 19684574 DOI: 10.1038/Ncb1930  1
2009 Li X, Cassidy JJ, Reinke CA, Fischboeck S, Carthew RW. A microRNA imparts robustness against environmental fluctuation during development. Cell. 137: 273-82. PMID 19379693 DOI: 10.1016/j.cell.2009.01.058  1
2009 Carthew RW, Sontheimer EJ. Origins and Mechanisms of miRNAs and siRNAs. Cell. 136: 642-55. PMID 19239886 DOI: 10.1016/j.cell.2009.01.035  1
2008 Reinke CA, Carthew RW. BMP signaling goes posttranscriptional in a microRNA sort of way. Developmental Cell. 15: 174-5. PMID 18694554 DOI: 10.1016/j.devcel.2008.07.015  1
2008 Hayashi T, Xu C, Carthew RW. Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye. Development (Cambridge, England). 135: 2787-96. PMID 18635611 DOI: 10.1242/dev.006189  1
2008 Lim do H, Kim J, Kim S, Carthew RW, Lee YS. Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila. Biochemical and Biophysical Research Communications. 371: 525-30. PMID 18454937 DOI: 10.1016/J.Bbrc.2008.04.118  1
2008 Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, Carthew R, Wu CI. Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Molecular Biology and Evolution. 25: 929-38. PMID 18296702 DOI: 10.1093/Molbev/Msn040  1
2008 Lu J, Shen Y, Wu Q, Kumar S, He B, Shi S, Carthew RW, Wang SM, Wu CI. The birth and death of microRNA genes in Drosophila. Nature Genetics. 40: 351-5. PMID 18278047 DOI: 10.1038/Ng.73  1
2008 Hilgenfeldt S, Erisken S, Carthew RW. Physical modeling of cell geometric order in an epithelial tissue. Proceedings of the National Academy of Sciences of the United States of America. 105: 907-11. PMID 18192402 DOI: 10.1073/Pnas.0711077105  1
2008 Zheng L, Carthew RW. Lola regulates cell fate by antagonizing Notch induction in the Drosophila eye. Mechanisms of Development. 125: 18-29. PMID 18053694 DOI: 10.1016/j.mod.2007.10.007  1
2007 Käfer J, Hayashi T, Marée AF, Carthew RW, Graner F. Cell adhesion and cortex contractility determine cell patterning in the Drosophila retina. Proceedings of the National Academy of Sciences of the United States of America. 104: 18549-54. PMID 18003929 DOI: 10.1073/pnas.0704235104  1
2007 Bei Y, Pressman S, Carthew R. SnapShot: small RNA-mediated epigenetic modifications. Cell. 130: 756. PMID 17719551 DOI: 10.1016/j.cell.2007.08.015  1
2007 Pressman S, Bei Y, Carthew R. Posttranscriptional gene silencing. Cell. 130: 570. PMID 17693263 DOI: 10.1016/j.cell.2007.07.042  1
2007 Carthew RW. Pattern formation in the Drosophila eye. Current Opinion in Genetics & Development. 17: 309-13. PMID 17618111 DOI: 10.1016/j.gde.2007.05.001  1
2007 Marques JT, Carthew RW. A call to arms: coevolution of animal viruses and host innate immune responses. Trends in Genetics : Tig. 23: 359-64. PMID 17467114 DOI: 10.1016/j.tig.2007.04.004  1
2007 Kim K, Lee YS, Carthew RW. Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes. Rna (New York, N.Y.). 13: 22-9. PMID 17123955 DOI: 10.1261/Rna.283207  1
2006 Kim K, Lee YS, Harris D, Nakahara K, Carthew RW. The RNAi pathway initiated by Dicer-2 in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 71: 39-44. PMID 17381278 DOI: 10.1101/Sqb.2006.71.008  1
2006 Carthew RW. Molecular biology. A new RNA dimension to genome control. Science (New York, N.Y.). 313: 305-6. PMID 16857925 DOI: 10.1126/science.1131186  1
2006 Wang XH, Aliyari R, Li WX, Li HW, Kim K, Carthew R, Atkinson P, Ding SW. RNA interference directs innate immunity against viruses in adult Drosophila. Science (New York, N.Y.). 312: 452-4. PMID 16556799 DOI: 10.1126/Science.1125694  1
2006 Carthew RW. Gene regulation by microRNAs. Current Opinion in Genetics & Development. 16: 203-8. PMID 16503132 DOI: 10.1016/j.gde.2006.02.012  1
2006 Bayraktar J, Zygmunt D, Carthew RW. Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo. Journal of Cell Science. 119: 711-21. PMID 16449319 DOI: 10.1242/jcs.02789  1
2005 Li X, Carthew RW. A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell. 123: 1267-77. PMID 16377567 DOI: 10.1016/j.cell.2005.10.040  1
2005 Nakahara K, Kim K, Sciulli C, Dowd SR, Minden JS, Carthew RW. Targets of microRNA regulation in the Drosophila oocyte proteome. Proceedings of the National Academy of Sciences of the United States of America. 102: 12023-8. PMID 16099838 DOI: 10.1073/Pnas.0500053102  1
2005 Sontheimer EJ, Carthew RW. Silence from within: endogenous siRNAs and miRNAs. Cell. 122: 9-12. PMID 16009127 DOI: 10.1016/j.cell.2005.06.030  1
2005 Carthew RW. Adhesion proteins and the control of cell shape. Current Opinion in Genetics & Development. 15: 358-63. PMID 15963712 DOI: 10.1016/j.gde.2005.06.002  1
2005 Hatfield SD, Shcherbata HR, Fischer KA, Nakahara K, Carthew RW, Ruohola-Baker H. Stem cell division is regulated by the microRNA pathway. Nature. 435: 974-8. PMID 15944714 DOI: 10.1038/nature03816  1
2004 Bettencourt-Dias M, Giet R, Sinka R, Mazumdar A, Lock WG, Balloux F, Zafiropoulos PJ, Yamaguchi S, Winter S, Carthew RW, Cooper M, Jones D, Frenz L, Glover DM. Genome-wide survey of protein kinases required for cell cycle progression. Nature. 432: 980-7. PMID 15616552 DOI: 10.1038/Nature03160  1
2004 Hayashi T, Carthew RW. Surface mechanics mediate pattern formation in the developing retina. Nature. 431: 647-52. PMID 15470418 DOI: 10.1038/nature02952  1
2004 Sontheimer EJ, Carthew RW. Molecular biology. Argonaute journeys into the heart of RISC. Science (New York, N.Y.). 305: 1409-10. PMID 15353786 DOI: 10.1126/science.1103076  1
2004 Nakahara K, Carthew RW. Expanding roles for miRNAs and siRNAs in cell regulation. Current Opinion in Cell Biology. 16: 127-33. PMID 15196554 DOI: 10.1016/j.ceb.2004.02.006  1
2004 Pham JW, Pellino JL, Lee YS, Carthew RW, Sontheimer EJ. A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell. 117: 83-94. PMID 15066284 DOI: 10.1016/S0092-8674(04)00258-2  1
2004 Lee YS, Nakahara K, Pham JW, Kim K, He Z, Sontheimer EJ, Carthew RW. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell. 117: 69-81. PMID 15066283 DOI: 10.1016/S0092-8674(04)00261-2  1
2003 Carthew RW. Making and breaking with nucleases and small RNAs. Nature Structural Biology. 10: 776-7. PMID 14513022 DOI: 10.1038/nsb1003-776  1
2003 Lee YS, Carthew RW. Making a better RNAi vector for Drosophila: use of intron spacers. Methods (San Diego, Calif.). 30: 322-9. PMID 12828946 DOI: 10.1016/S1046-2023(03)00051-3  1
2003 Takemaru K, Yamaguchi S, Lee YS, Zhang Y, Carthew RW, Moon RT. Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. Nature. 422: 905-9. PMID 12712206 DOI: 10.1038/Nature01570  1
2002 Carthew RW. RNA interference: the fragile X syndrome connection. Current Biology : Cb. 12: R852-4. PMID 12498706 DOI: 10.1016/S0960-9822(02)01352-0  1
2002 Li S, Xu C, Carthew RW. Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack. Molecular and Cellular Biology. 22: 6854-65. PMID 12215542 DOI: 10.1128/MCB.22.19.6854-6865.2002  1
2002 Kennerdell JR, Yamaguchi S, Carthew RW. RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes & Development. 16: 1884-9. PMID 12154120 DOI: 10.1101/gad.990802  1
2001 Carthew RW. Gene silencing by double-stranded RNA. Current Opinion in Cell Biology. 13: 244-8. PMID 11248560 DOI: 10.1016/S0955-0674(00)00204-0  1
2000 Xu C, Kauffmann RC, Zhang J, Kladny S, Carthew RW. Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye. Cell. 103: 87-97. PMID 11051550  1
2000 Kennerdell JR, Carthew RW. Heritable gene silencing in Drosophila using double-stranded RNA. Nature Biotechnology. 18: 896-8. PMID 10932163 DOI: 10.1038/78531  1
2000 Carthew RW, Xu C. Endocytosis: why not wait to deubiquitinate? Current Biology : Cb. 10: R532-4. PMID 10898994 DOI: 10.1016/S0960-9822(00)00587-X  1
1999 Dong X, Tsuda L, Zavitz KH, Lin M, Li S, Carthew RW, Zipursky SL. ebi regulates epidermal growth factor receptor signaling pathways in Drosophila. Genes & Development. 13: 954-65. PMID 10215623 DOI: 10.1101/Gad.13.8.954  1
1998 Kennerdell JR, Carthew RW. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell. 95: 1017-26. PMID 9875855 DOI: 10.1016/S0092-8674(00)81725-0  1
1998 Zhang J, Carthew RW. Interactions between Wingless and DFz2 during Drosophila wing development. Development (Cambridge, England). 125: 3075-85. PMID 9671581  1
1998 Zhang J, Guenther MG, Carthew RW, Lazar MA. Proteasomal regulation of nuclear receptor corepressor-mediated repression. Genes & Development. 12: 1775-80. PMID 9637679 DOI: 10.1101/Gad.12.12.1775  1
1997 Li S, Li Y, Carthew RW, Lai ZC. Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack. Cell. 90: 469-78. PMID 9267027 DOI: 10.1016/S0092-8674(00)80507-3  1
1996 Kauffmann RC, Li S, Gallagher PA, Zhang J, Carthew RW. Ras1 signaling and transcriptional competence in the R7 cell of Drosophila. Genes & Development. 10: 2167-78. PMID 8804311  1
1995 Zheng L, Zhang J, Carthew RW. frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. Development (Cambridge, England). 121: 3045-55. PMID 7555730  1
1995 Kauffmann RC, Qian Y, Vogt A, Sebti SM, Hamilton AD, Carthew RW. Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 92: 10919-23. PMID 7479910 DOI: 10.1073/Pnas.92.24.10919  1
1994 Carthew RW, Neufeld TP, Rubin GM. Identification of genes that interact with the sina gene in Drosophila eye development. Proceedings of the National Academy of Sciences of the United States of America. 91: 11689-93. PMID 7972125 DOI: 10.1073/Pnas.91.24.11689  1
1992 Baker NE, Moses K, Nakahara D, Ellis MC, Carthew RW, Rubin GM. Mutations on the second chromosome affecting the Drosophila eye. Journal of Neurogenetics. 8: 85-100. PMID 1634999 DOI: 10.3109/01677069209084154  1
1992 Simon MA, Carthew RW, Fortini ME, Gaul U, Mardon G, Rubin GM. Signal transduction pathway initiated by activation of the sevenless tyrosine kinase receptor. Cold Spring Harbor Symposia On Quantitative Biology. 57: 375-80. PMID 1339672 DOI: 10.1101/Sqb.1992.057.01.042  1
1991 Neufeld TP, Carthew RW, Rubin GM. Evolution of gene position: chromosomal arrangement and sequence comparison of the Drosophila melanogaster and Drosophila virilis sina and Rh4 genes. Proceedings of the National Academy of Sciences of the United States of America. 88: 10203-7. PMID 1946441 DOI: 10.1073/pnas.88.22.10203  1
1991 Hariharan IK, Carthew RW, Rubin GM. The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination. Cell. 67: 717-22. PMID 1934069 DOI: 10.1016/0092-8674(91)90066-8  1
1990 Carthew RW, Rubin GM. seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye. Cell. 63: 561-77. PMID 2146028 DOI: 10.1016/0092-8674(90)90452-K  1
1988 Chodosh LA, Baldwin AS, Carthew RW, Sharp PA. Human CCAAT-binding proteins have heterologous subunits. Cell. 53: 11-24. PMID 3349524 DOI: 10.1016/0092-8674(88)90483-7  1
1988 Carthew RW, Samuels M, Sharp PA. Formation of transcription preinitiation complexes with an amanitin-resistant RNA polymerase II. The Journal of Biological Chemistry. 263: 17128-35. PMID 3182839  1
1987 Chodosh LA, Carthew RW, Morgan JG, Crabtree GR, Sharp PA. The adenovirus major late transcription factor activates the rat gamma-fibrinogen promoter. Science (New York, N.Y.). 238: 684-8. PMID 3672119  1
1987 Carthew RW, Chodosh LA, Sharp PA. The major late transcription factor binds to and activates the mouse metallothionein I promoter. Genes & Development. 1: 973-80. PMID 3428603 DOI: 10.1101/Gad.1.9.973  1
1986 Chodosh LA, Carthew RW, Sharp PA. A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Molecular and Cellular Biology. 6: 4723-33. PMID 3796614 DOI: 10.1128/Mcb.6.12.4723  1
1985 Carthew RW, Chodosh LA, Sharp PA. An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell. 43: 439-48. PMID 4075400 DOI: 10.1016/0092-8674(85)90174-6  1
1985 Sopta M, Carthew RW, Greenblatt J. Isolation of three proteins that bind to mammalian RNA polymerase II. The Journal of Biological Chemistry. 260: 10353-60. PMID 3860504  1
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