Adrian Salic - Publications

Affiliations: 
Cell Biology Harvard Medical School, Boston, MA, United States 
Website:
https://salic.med.harvard.edu/

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 de Almeida Magalhaes T, Liu J, Chan C, Borges KS, Zhang J, Kane AJ, Wierbowski BM, Ge Y, Liu Z, Mannam P, Zeve D, Weiss R, Breault DT, Huang P, Salic A. Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens. Developmental Cell. PMID 38154460 DOI: 10.1016/j.devcel.2023.11.027  0.831
2023 Quek RT, Hardy KS, Walker SG, Nguyen DT, de Almeida Magalhães T, Salic A, Gopalakrishnan SM, Silver PA, Mitchison TJ. Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity. Acs Chemical Biology. PMID 36795767 DOI: 10.1021/acschembio.2c00908  0.452
2022 de Almeida Magalhães T, Alencastro Veiga Cruzeiro G, Ribeiro de Sousa G, Englinger B, Peinado Nagano LF, Ancliffe M, Rodrigues da Silva K, Jiang L, Gojo J, Cherry Liu Y, Carline B, Kuchibhotla M, Pinto Saggioro F, Kazue Nagahashi Marie S, Mieko Oba-Shinjo S, ... ... Salic A, et al. Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in Supratentorial Ependymoma. Neuro-Oncology. PMID 35640920 DOI: 10.1093/neuonc/noac147  0.307
2022 Huang P, Wierbowski BM, Lian T, Chan C, García-Linares S, Jiang J, Salic A. Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Developmental Cell. 57: 670-685.e8. PMID 35231446 DOI: 10.1016/j.devcel.2022.02.008  0.836
2022 Liu YC, Wierbowski BM, Salic A. Hedgehog pathway modulation by glypican 3-conjugated heparan sulfate. Journal of Cell Science. PMID 35142364 DOI: 10.1242/jcs.259297  0.82
2021 Li W, Wang L, Wierbowski BM, Lu M, Dong F, Liu W, Li S, Wang P, Salic A, Gong X. Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nature Communications. 12: 6966. PMID 34845226 DOI: 10.1038/s41467-021-27257-w  0.811
2021 Petrov K, de Almeida Magalhaes T, Salic A. Mechanism and ultrasensitivity in Hedgehog signaling revealed by Patched1 disease mutations. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526656 DOI: 10.1073/pnas.2006800118  0.821
2020 Wierbowski BM, Petrov K, Aravena L, Gu G, Xu Y, Salic A. Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. Developmental Cell. PMID 33038332 DOI: 10.1016/j.devcel.2020.09.017  0.816
2020 Petrov K, Wierbowski BM, Liu J, Salic A. Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway. Developmental Cell. PMID 32860743 DOI: 10.1016/J.Devcel.2020.08.002  0.795
2020 Magalhães TdA, Cruzeiro GAV, Borges KS, Yulu CL, Souza GRd, Silva KRd, Scridelli CA, Salic A, Tone LG. Abstract A30: Alisertib acts synergistically with sonidegib by modulating primary cilia assembly in a pediatric RELA ependymoma cell line Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A30  0.434
2020 Salic A, Wierbowski B, Petrov K. Lipids and Hedgehogs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00180  0.744
2018 Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A. Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell. 175: 295-297. PMID 30241610 DOI: 10.1016/j.cell.2018.09.003  0.798
2018 Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A. Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell. PMID 29804838 DOI: 10.1016/J.Cell.2018.04.029  0.809
2017 Petrov K, Wierbowski BM, Salic A. Sending and Receiving Hedgehog Signals. Annual Review of Cell and Developmental Biology. PMID 28693388 DOI: 10.1146/Annurev-Cellbio-100616-060847  0.793
2016 Tukachinsky H, Petrov K, Watanabe M, Salic A. Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647915 DOI: 10.1073/Pnas.1606719113  0.811
2016 Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A. Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell. PMID 27545348 DOI: 10.1016/J.Cell.2016.08.003  0.834
2016 Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070  0.439
2015 Jao CY, Nedelcu D, Lopez LV, Samarakoon TN, Welti R, Salic A. Bioorthogonal probes for imaging sterols in cells. Chembiochem : a European Journal of Chemical Biology. 16: 611-7. PMID 25663046 DOI: 10.1002/Cbic.201402715  0.792
2015 Jao CY, Roth M, Welti R, Salic A. Biosynthetic labeling and two-color imaging of phospholipids in cells. Chembiochem : a European Journal of Chemical Biology. 16: 472-6. PMID 25586136 DOI: 10.1002/Cbic.201402149  0.752
2015 Salic A. Hedgehogs and Lipids The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.90.3  0.561
2014 Iyoshi S, Cheng J, Tatematsu T, Takatori S, Taki M, Yamamoto Y, Salic A, Fujimoto T. Asymmetrical distribution of choline phospholipids revealed by click chemistry and freeze-fracture electron microscopy. Acs Chemical Biology. 9: 2217-22. PMID 25122546 DOI: 10.1021/Cb500558N  0.329
2014 Signer RA, Magee JA, Salic A, Morrison SJ. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature. 509: 49-54. PMID 24670665 DOI: 10.1038/Nature13035  0.332
2013 Nedelcu D, Liu J, Xu Y, Jao C, Salic A. Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling. Nature Chemical Biology. 9: 557-64. PMID 23831757 DOI: 10.1038/Nchembio.1290  0.81
2012 Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A. Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand. Cell Reports. 2: 308-20. PMID 22902404 DOI: 10.1016/J.Celrep.2012.07.010  0.817
2012 Liu J, Xu Y, Stoleru D, Salic A. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proceedings of the National Academy of Sciences of the United States of America. 109: 413-8. PMID 22160674 DOI: 10.1073/Pnas.1111561108  0.369
2011 Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657  0.426
2011 Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. The Journal of Cell Biology. 192: 825-38. PMID 21357747 DOI: 10.1083/Jcb.201008090  0.789
2010 Tukachinsky H, Lopez LV, Salic A. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. The Journal of Cell Biology. 191: 415-28. PMID 20956384 DOI: 10.1083/Jcb.201004108  0.815
2010 Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, ... Salic A, et al. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Nature Chemical Biology. 6: 829-36. PMID 20890287 DOI: 10.1038/Nchembio.453  0.477
2009 Jao CY, Roth M, Welti R, Salic A. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 15332-7. PMID 19706413 DOI: 10.1073/Pnas.0907864106  0.765
2008 Jao CY, Salic A. Exploring RNA transcription and turnover in vivo by using click chemistry. Proceedings of the National Academy of Sciences of the United States of America. 105: 15779-84. PMID 18840688 DOI: 10.1073/Pnas.0808480105  0.72
2008 Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Current Biology : Cb. 18: 1256-61. PMID 18718761 DOI: 10.1016/J.Cub.2008.07.092  0.698
2008 Salic A, Mitchison TJ. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 2415-20. PMID 18272492 DOI: 10.1073/Pnas.0712168105  0.468
2007 Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E. Lrp6 is required for convergent extension during Xenopus gastrulation. Development (Cambridge, England). 134: 4095-106. PMID 17965054 DOI: 10.1242/Dev.010272  0.452
2007 Boyarchuk Y, Salic A, Dasso M, Arnaoutov A. Bub1 is essential for assembly of the functional inner centromere. The Journal of Cell Biology. 176: 919-28. PMID 17389228 DOI: 10.1083/Jcb.200609044  0.372
2005 Salic A, King RW. Identifying small molecule inhibitors of the ubiquitin-proteasome pathway in Xenopus egg extracts. Methods in Enzymology. 399: 567-85. PMID 16338382 DOI: 10.1016/S0076-6879(05)99038-1  0.601
2004 Salic A, Waters JC, Mitchison TJ. Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell. 118: 567-78. PMID 15339662 DOI: 10.1016/J.Cell.2004.08.016  0.481
2003 Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. Plos Biology. 1: E10. PMID 14551908 DOI: 10.1371/Journal.Pbio.0000010  0.587
2003 Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M. Anteroposterior patterning in hemichordates and the origins of the chordate nervous system. Cell. 113: 853-65. PMID 12837244 DOI: 10.1016/S0092-8674(03)00469-0  0.709
2002 Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO. A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. The Journal of Biological Chemistry. 277: 34727-35. PMID 12121999 DOI: 10.1074/Jbc.M204989200  0.583
2001 Lee E, Salic A, Kirschner MW. Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon. The Journal of Cell Biology. 154: 983-93. PMID 11524435 DOI: 10.1083/Jcb.200102074  0.506
2001 Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1. Genes & Development. 15: 1759-64. PMID 11459825 DOI: 10.1101/Gad.897901  0.547
2000 Salic A, Lee E, Mayer L, Kirschner MW. Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Molecular Cell. 5: 523-32. PMID 10882137 DOI: 10.1016/S1097-2765(00)80446-3  0.501
1998 Kroll KL, Salic AN, Evans LM, Kirschner MW. Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation. Development (Cambridge, England). 125: 3247-58. PMID 9671596  0.693
1997 Salic AN, Kroll KL, Evans LM, Kirschner MW. Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos. Development (Cambridge, England). 124: 4739-48. PMID 9428410  0.731
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