Year |
Citation |
Score |
2023 |
de Almeida Magalhaes T, Liu J, Chan C, Borges KS, Zhang J, Kane AJ, Wierbowski BM, Ge Y, Liu Z, Mannam P, Zeve D, Weiss R, Breault DT, Huang P, Salic A. Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens. Developmental Cell. PMID 38154460 DOI: 10.1016/j.devcel.2023.11.027 |
0.831 |
|
2023 |
Quek RT, Hardy KS, Walker SG, Nguyen DT, de Almeida Magalhães T, Salic A, Gopalakrishnan SM, Silver PA, Mitchison TJ. Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity. Acs Chemical Biology. PMID 36795767 DOI: 10.1021/acschembio.2c00908 |
0.452 |
|
2022 |
de Almeida Magalhães T, Alencastro Veiga Cruzeiro G, Ribeiro de Sousa G, Englinger B, Peinado Nagano LF, Ancliffe M, Rodrigues da Silva K, Jiang L, Gojo J, Cherry Liu Y, Carline B, Kuchibhotla M, Pinto Saggioro F, Kazue Nagahashi Marie S, Mieko Oba-Shinjo S, ... ... Salic A, et al. Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in Supratentorial Ependymoma. Neuro-Oncology. PMID 35640920 DOI: 10.1093/neuonc/noac147 |
0.307 |
|
2022 |
Huang P, Wierbowski BM, Lian T, Chan C, García-Linares S, Jiang J, Salic A. Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Developmental Cell. 57: 670-685.e8. PMID 35231446 DOI: 10.1016/j.devcel.2022.02.008 |
0.836 |
|
2022 |
Liu YC, Wierbowski BM, Salic A. Hedgehog pathway modulation by glypican 3-conjugated heparan sulfate. Journal of Cell Science. PMID 35142364 DOI: 10.1242/jcs.259297 |
0.82 |
|
2021 |
Li W, Wang L, Wierbowski BM, Lu M, Dong F, Liu W, Li S, Wang P, Salic A, Gong X. Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nature Communications. 12: 6966. PMID 34845226 DOI: 10.1038/s41467-021-27257-w |
0.811 |
|
2021 |
Petrov K, de Almeida Magalhaes T, Salic A. Mechanism and ultrasensitivity in Hedgehog signaling revealed by Patched1 disease mutations. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526656 DOI: 10.1073/pnas.2006800118 |
0.821 |
|
2020 |
Wierbowski BM, Petrov K, Aravena L, Gu G, Xu Y, Salic A. Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. Developmental Cell. PMID 33038332 DOI: 10.1016/j.devcel.2020.09.017 |
0.816 |
|
2020 |
Petrov K, Wierbowski BM, Liu J, Salic A. Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway. Developmental Cell. PMID 32860743 DOI: 10.1016/J.Devcel.2020.08.002 |
0.795 |
|
2020 |
Magalhães TdA, Cruzeiro GAV, Borges KS, Yulu CL, Souza GRd, Silva KRd, Scridelli CA, Salic A, Tone LG. Abstract A30: Alisertib acts synergistically with sonidegib by modulating primary cilia assembly in a pediatric RELA ependymoma cell line Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A30 |
0.434 |
|
2020 |
Salic A, Wierbowski B, Petrov K. Lipids and Hedgehogs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00180 |
0.744 |
|
2018 |
Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A. Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell. 175: 295-297. PMID 30241610 DOI: 10.1016/j.cell.2018.09.003 |
0.798 |
|
2018 |
Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A. Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell. PMID 29804838 DOI: 10.1016/J.Cell.2018.04.029 |
0.809 |
|
2017 |
Petrov K, Wierbowski BM, Salic A. Sending and Receiving Hedgehog Signals. Annual Review of Cell and Developmental Biology. PMID 28693388 DOI: 10.1146/Annurev-Cellbio-100616-060847 |
0.792 |
|
2016 |
Tukachinsky H, Petrov K, Watanabe M, Salic A. Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647915 DOI: 10.1073/Pnas.1606719113 |
0.811 |
|
2016 |
Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A. Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell. PMID 27545348 DOI: 10.1016/J.Cell.2016.08.003 |
0.834 |
|
2016 |
Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070 |
0.439 |
|
2015 |
Jao CY, Nedelcu D, Lopez LV, Samarakoon TN, Welti R, Salic A. Bioorthogonal probes for imaging sterols in cells. Chembiochem : a European Journal of Chemical Biology. 16: 611-7. PMID 25663046 DOI: 10.1002/Cbic.201402715 |
0.792 |
|
2015 |
Jao CY, Roth M, Welti R, Salic A. Biosynthetic labeling and two-color imaging of phospholipids in cells. Chembiochem : a European Journal of Chemical Biology. 16: 472-6. PMID 25586136 DOI: 10.1002/Cbic.201402149 |
0.752 |
|
2015 |
Salic A. Hedgehogs and Lipids The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.90.3 |
0.561 |
|
2014 |
Iyoshi S, Cheng J, Tatematsu T, Takatori S, Taki M, Yamamoto Y, Salic A, Fujimoto T. Asymmetrical distribution of choline phospholipids revealed by click chemistry and freeze-fracture electron microscopy. Acs Chemical Biology. 9: 2217-22. PMID 25122546 DOI: 10.1021/Cb500558N |
0.33 |
|
2014 |
Signer RA, Magee JA, Salic A, Morrison SJ. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature. 509: 49-54. PMID 24670665 DOI: 10.1038/Nature13035 |
0.332 |
|
2013 |
Nedelcu D, Liu J, Xu Y, Jao C, Salic A. Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling. Nature Chemical Biology. 9: 557-64. PMID 23831757 DOI: 10.1038/Nchembio.1290 |
0.81 |
|
2012 |
Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A. Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand. Cell Reports. 2: 308-20. PMID 22902404 DOI: 10.1016/J.Celrep.2012.07.010 |
0.818 |
|
2012 |
Liu J, Xu Y, Stoleru D, Salic A. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proceedings of the National Academy of Sciences of the United States of America. 109: 413-8. PMID 22160674 DOI: 10.1073/Pnas.1111561108 |
0.369 |
|
2011 |
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657 |
0.425 |
|
2011 |
Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. The Journal of Cell Biology. 192: 825-38. PMID 21357747 DOI: 10.1083/Jcb.201008090 |
0.789 |
|
2010 |
Tukachinsky H, Lopez LV, Salic A. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. The Journal of Cell Biology. 191: 415-28. PMID 20956384 DOI: 10.1083/Jcb.201004108 |
0.816 |
|
2010 |
Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, ... Salic A, et al. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Nature Chemical Biology. 6: 829-36. PMID 20890287 DOI: 10.1038/Nchembio.453 |
0.477 |
|
2009 |
Jao CY, Roth M, Welti R, Salic A. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 15332-7. PMID 19706413 DOI: 10.1073/Pnas.0907864106 |
0.765 |
|
2008 |
Jao CY, Salic A. Exploring RNA transcription and turnover in vivo by using click chemistry. Proceedings of the National Academy of Sciences of the United States of America. 105: 15779-84. PMID 18840688 DOI: 10.1073/Pnas.0808480105 |
0.72 |
|
2008 |
Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Current Biology : Cb. 18: 1256-61. PMID 18718761 DOI: 10.1016/J.Cub.2008.07.092 |
0.695 |
|
2008 |
Salic A, Mitchison TJ. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 2415-20. PMID 18272492 DOI: 10.1073/Pnas.0712168105 |
0.468 |
|
2007 |
Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E. Lrp6 is required for convergent extension during Xenopus gastrulation. Development (Cambridge, England). 134: 4095-106. PMID 17965054 DOI: 10.1242/Dev.010272 |
0.452 |
|
2007 |
Boyarchuk Y, Salic A, Dasso M, Arnaoutov A. Bub1 is essential for assembly of the functional inner centromere. The Journal of Cell Biology. 176: 919-28. PMID 17389228 DOI: 10.1083/Jcb.200609044 |
0.372 |
|
2005 |
Salic A, King RW. Identifying small molecule inhibitors of the ubiquitin-proteasome pathway in Xenopus egg extracts. Methods in Enzymology. 399: 567-85. PMID 16338382 DOI: 10.1016/S0076-6879(05)99038-1 |
0.601 |
|
2004 |
Salic A, Waters JC, Mitchison TJ. Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell. 118: 567-78. PMID 15339662 DOI: 10.1016/J.Cell.2004.08.016 |
0.481 |
|
2003 |
Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. Plos Biology. 1: E10. PMID 14551908 DOI: 10.1371/Journal.Pbio.0000010 |
0.586 |
|
2003 |
Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M. Anteroposterior patterning in hemichordates and the origins of the chordate nervous system. Cell. 113: 853-65. PMID 12837244 DOI: 10.1016/S0092-8674(03)00469-0 |
0.709 |
|
2002 |
Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO. A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. The Journal of Biological Chemistry. 277: 34727-35. PMID 12121999 DOI: 10.1074/Jbc.M204989200 |
0.583 |
|
2001 |
Lee E, Salic A, Kirschner MW. Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon. The Journal of Cell Biology. 154: 983-93. PMID 11524435 DOI: 10.1083/Jcb.200102074 |
0.505 |
|
2001 |
Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1. Genes & Development. 15: 1759-64. PMID 11459825 DOI: 10.1101/Gad.897901 |
0.547 |
|
2000 |
Salic A, Lee E, Mayer L, Kirschner MW. Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Molecular Cell. 5: 523-32. PMID 10882137 DOI: 10.1016/S1097-2765(00)80446-3 |
0.501 |
|
1998 |
Kroll KL, Salic AN, Evans LM, Kirschner MW. Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation. Development (Cambridge, England). 125: 3247-58. PMID 9671596 |
0.69 |
|
1997 |
Salic AN, Kroll KL, Evans LM, Kirschner MW. Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos. Development (Cambridge, England). 124: 4739-48. PMID 9428410 |
0.728 |
|
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