Mark D. Distefano

Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
protein engineering, protein prenylation and cellular patterning
"Mark D. Distefano"

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Glenn A. Berchtold grad student 1989 MIT
 (Enzymatic mercuric ion reduction : a mechanistic investigation employing site-directed mutagenesis)
Christopher T. Walsh grad student 1989 MIT
Peter B. Dervan post-doc 1989-1992 Caltech


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Tamara A. Kale grad student 2001 UMN
Hao Kuang grad student 2001 UMN
John R. Jalas grad student 2003 UMN
Dongfeng Qi grad student 2003 UMN
Cheng-Min Tann grad student 2004 UMN
Benjamin P. Duckworth grad student 2007 UMN
James W. Wollack grad student 2009 UMN
Erick K. Leggans grad student 2010 UMN
Stepan Lenevich grad student 2010 UMN
Kelly J. Kyro grad student 2011 UMN
Daniel Abate Pella grad student 2012 UMN
Joshua D. Ochocki grad student 2012 UMN
Mohammad Rashidian grad student 2013 UMN
Jonathan K. Dozier grad student 2014 UMN
Yen-Chih Wang grad student 2014 UMN
Kiall F Suazo grad student 2014-2021 UMN
Taysir K Bader grad student 2017-2023 University of Minnesota - Minneapolis
Matthew D Hammers post-doc 2016- UMN
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Zhang Y, Wang Y, Uslu S, et al. (2022) Enzymatic Construction of DARPin-Based Targeted Delivery Systems Using Protein Farnesyltransferase and a Capture and Release Strategy. International Journal of Molecular Sciences. 23
Morstein J, Bader T, Cardillo AL, et al. (2022) Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation. Acs Chemical Biology
Wang Y, Wagner CR, Distefano MD. (2022) Manipulating Cell Fates with Protein Conjugates. Bioconjugate Chemistry
Maxwell ZA, Suazo KF, Brown HMG, et al. (2022) Combining Isoprenoid Probes with Antibody Markers for Mass Cytometric Analysis of Prenylation in Single Cells. Analytical Chemistry
Schey GL, Buttery PH, Hildebrandt ER, et al. (2021) MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International Journal of Molecular Sciences. 22
Suazo KF, Park KY, Distefano MD. (2021) A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications. Chemical Reviews
Suazo KF, Jeong A, Ahmadi M, et al. (2021) Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells. Scientific Reports. 11: 4367
Hammers MD, Hodny MH, Bader TK, et al. (2020) Two-photon uncaging of bioactive thiols in live cells at wavelengths above 800 nm. Organic & Biomolecular Chemistry
Qu W, Suazo KF, Liu W, et al. (2020) Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function. Molecular Neurobiology
Mangubat-Medina AE, Trial HO, Vargas RD, et al. (2020) Red-shifted backbone N-H photocaging agents. Organic & Biomolecular Chemistry
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