Mark D. Distefano

Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
protein engineering, protein prenylation and cellular patterning
"Mark D. Distefano"

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Glenn A. Berchtold grad student 1989 MIT
 (Enzymatic mercuric ion reduction : a mechanistic investigation employing site-directed mutagenesis)
Christopher T. Walsh grad student 1989 MIT
Peter B. Dervan post-doc 1989-1992 Caltech


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Tamara A. Kale grad student 2001 UMN
Hao Kuang grad student 2001 UMN
John R. Jalas grad student 2003 UMN
Dongfeng Qi grad student 2003 UMN
Cheng-Min Tann grad student 2004 UMN
Benjamin P. Duckworth grad student 2007 UMN
James W. Wollack grad student 2009 UMN
Erick K. Leggans grad student 2010 UMN
Stepan Lenevich grad student 2010 UMN
Kelly J. Kyro grad student 2011 UMN
Daniel Abate Pella grad student 2012 UMN
Joshua D. Ochocki grad student 2012 UMN
Mohammad Rashidian grad student 2013 UMN
Jonathan K. Dozier grad student 2014 UMN
Yen-Chih Wang grad student 2014 UMN
Matthew D Hammers post-doc 2016- UMN
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Schey GL, Buttery PH, Hildebrandt ER, et al. (2021) MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International Journal of Molecular Sciences. 22
Suazo KF, Park KY, Distefano MD. (2021) A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications. Chemical Reviews
Suazo KF, Jeong A, Ahmadi M, et al. (2021) Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells. Scientific Reports. 11: 4367
Wang Y, Kilic O, Csizmar CM, et al. (2020) Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical Science. 12: 331-340
Hammers MD, Hodny MH, Bader TK, et al. (2020) Two-photon uncaging of bioactive thiols in live cells at wavelengths above 800 nm. Organic & Biomolecular Chemistry
Qu W, Suazo KF, Liu W, et al. (2020) Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function. Molecular Neurobiology
Kilic O, Matos de Souza MR, Almotlak A, et al. (2020) Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T-cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression. Journal of Medicinal Chemistry
Brandt AC, McNally L, Lorimer EL, et al. (2020) Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy. Proceedings of the National Academy of Sciences of the United States of America
Bader TK, Xu F, Hodny MH, et al. (2019) A methoxy-substituted nitrodibenzofuran-based protecting group with an improved two-photon action cross-section for thiol protection in solid phase peptide synthesis. The Journal of Organic Chemistry
Zhang Y, Auger S, Schaefer JV, et al. (2019) Site-Selective Enzymatic Labeling of Designed Ankyrin Repeat Proteins Using Protein Farnesyltransferase. Methods in Molecular Biology (Clifton, N.J.). 2033: 207-219
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