Mark D. Distefano

Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
protein engineering, protein prenylation and cellular patterning
"Mark D. Distefano"

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Glenn A. Berchtold grad student 1989 MIT
 (Enzymatic mercuric ion reduction : a mechanistic investigation employing site-directed mutagenesis)
Christopher  T. Walsh grad student 1989 MIT
Peter B. Dervan post-doc 1989-1992 Caltech


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Tamara A. Kale grad student 2001 UMN
Hao Kuang grad student 2001 UMN
John R. Jalas grad student 2003 UMN
Dongfeng Qi grad student 2003 UMN
Cheng-Min Tann grad student 2004 UMN
Benjamin P. Duckworth grad student 2007 UMN
James W. Wollack grad student 2009 UMN
Erick K. Leggans grad student 2010 UMN
Stepan Lenevich grad student 2010 UMN
Kelly J. Kyro grad student 2011 UMN
Daniel Abate Pella grad student 2012 UMN
Joshua D. Ochocki grad student 2012 UMN
Mohammad Rashidian grad student 2013 UMN
Jonathan K. Dozier grad student 2014 UMN
Yen-Chih Wang grad student 2014 UMN
Matthew D Hammers post-doc 2016- UMN
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Zhang Y, Park KY, Suazo KF, et al. (2018) Recent progress in enzymatic protein labelling techniques and their applications. Chemical Society Reviews
Suazo KF, Hurben AK, Liu K, et al. (2018) Metabolic Labeling of Prenylated Proteins Using Alkyne-Modified Isoprenoid Analogues. Current Protocols in Chemical Biology. e46
Pujari SS, Zhang Y, Ji S, et al. (2018) Site-specific cross-linking of proteins to DNA via a new bioorthogonal approach employing oxime ligation. Chemical Communications (Cambridge, England)
Jeong A, Suazo KF, Wood WG, et al. (2018) Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease. Critical Reviews in Biochemistry and Molecular Biology. 53: 279-310
Fisher SA, Tam RY, Fokina A, et al. (2018) Photo-immobilized EGF chemical gradients differentially impact breast cancer cell invasion and drug response in defined 3D hydrogels. Biomaterials
Blanden MJ, Suazo KF, Hildebrandt ER, et al. (2017) Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome. The Journal of Biological Chemistry
Diaz-Rodriguez V, Hsu ET, Ganusova E, et al. (2017) a-Factor Analogues Containing Alkyne- and Azide-Functionalized Isoprenoids Are Efficiently Enzymatically Processed and Retain Wild-Type Bioactivity. Bioconjugate Chemistry
Suazo KF, Schaber C, Palsuledesai CC, et al. (2016) Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue. Scientific Reports. 6: 38615
Mahmoodi MM, Fisher SA, Tam RY, et al. (2016) 6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning. Organic & Biomolecular Chemistry
Palsuledesai CC, Ochocki JD, Kuhns MM, et al. (2016) Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells. Acs Chemical Biology
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