Year |
Citation |
Score |
2018 |
Posfai D, Sylvester K, Reddy A, Ganley JG, Wirth J, Cullen QE, Dave T, Kato N, Dave SS, Derbyshire ER. Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection. Plos Pathogens. 14: e1007057. PMID 29775485 DOI: 10.1371/Journal.Ppat.1007057 |
0.326 |
|
2018 |
Kato N, March S, Bhatia SN, Marti M. Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages. Methods in Molecular Biology (Clifton, N.J.). 1787: 41-52. PMID 29736708 DOI: 10.1007/978-1-4939-7847-2_3 |
0.318 |
|
2018 |
Posfai D, Eubanks AL, Keim AI, Lu KY, Wang GZ, Hughes PF, Kato N, Haystead TA, Derbyshire ER. Identification of Hsp90 inhibitors with anti-Plasmodium activity. Antimicrobial Agents and Chemotherapy. PMID 29339390 DOI: 10.1128/Aac.01799-17 |
0.332 |
|
2017 |
Maetani M, Zoller J, Melillo B, Verho O, Kato N, Pu J, Comer E, Schreiber SL. Synthesis of a bicyclic azetidine with in vivo antimalarial activity enabled by stereospecific, directed C(sp(3))-H arylation. Journal of the American Chemical Society. PMID 28732448 DOI: 10.1021/Jacs.7B06994 |
0.302 |
|
2017 |
Maetani M, Kato N, Jabor VAP, Calil FA, Nonato MC, Scherer CA, Schreiber SL. Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase. Acs Medicinal Chemistry Letters. 8: 438-442. PMID 28435533 DOI: 10.1021/Acsmedchemlett.7B00030 |
0.354 |
|
2016 |
Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan G, Duffy S, Eckley S, et al. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. PMID 27602946 DOI: 10.1038/Nature19804 |
0.318 |
|
2016 |
Swann J, Corey V, Scherer CA, Kato N, Comer E, Maetani M, Antonova-Koch Y, Reimer C, Gagaring K, Ibanez M, Plouffe D, Zeeman AM, Kocken CH, McNamara CW, Schreiber SL, et al. High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria. Acs Infectious Diseases. 2: 281-293. PMID 27275010 DOI: 10.1021/Acsinfecdis.5B00143 |
0.331 |
|
2015 |
Plouffe DM, Wree M, Du AY, Meister S, Li F, Patra K, Lubar A, Okitsu SL, Flannery EL, Kato N, Tanaseichuk O, Comer E, Zhou B, Kuhen K, Zhou Y, et al. High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission. Cell Host & Microbe. PMID 26749441 DOI: 10.1016/J.Chom.2015.12.001 |
0.339 |
|
2014 |
Comer E, Beaudoin JA, Kato N, Fitzgerald ME, Heidebrecht RW, Lee Md, Masi D, Mercier M, Mulrooney C, Muncipinto G, Rowley A, Crespo-Llado K, Serrano AE, Lukens AK, Wiegand RC, et al. Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. Journal of Medicinal Chemistry. 57: 8496-502. PMID 25211597 DOI: 10.1021/Jm500994N |
0.312 |
|
2014 |
Zou B, Nagle A, Chatterjee AK, Leong SY, Tan LJ, Sim WL, Mishra P, Guntapalli P, Tully DC, Lakshminarayana SB, Lim CS, Tan YC, Abas SN, Bodenreider C, Kuhen KL, ... ... Kato N, et al. Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages. Acs Medicinal Chemistry Letters. 5: 947-50. PMID 25147620 DOI: 10.1021/Ml500244M |
0.314 |
|
2014 |
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J. Chemical interrogation of the malaria kinome. Chembiochem : a European Journal of Chemical Biology. 15: 1920-30. PMID 25111632 DOI: 10.1002/Cbic.201400025 |
0.328 |
|
2013 |
McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, ... ... Kato N, et al. Targeting Plasmodium PI(4)K to eliminate malaria. Nature. 504: 248-253. PMID 24284631 DOI: 10.1038/Nature12782 |
0.331 |
|
2011 |
Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, ... ... Kato N, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.). 334: 1372-7. PMID 22096101 DOI: 10.1126/Science.1211936 |
0.345 |
|
2011 |
Nam TG, McNamara CW, Bopp S, Dharia NV, Meister S, Bonamy GM, Plouffe DM, Kato N, McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA. A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor. Acs Chemical Biology. 6: 1214-22. PMID 21866942 DOI: 10.1021/Cb200105D |
0.317 |
|
2008 |
Kato N, Mueller CR, Fuchs JF, McElroy K, Wessely V, Higgs S, Christensen BM. Evaluation of the function of a type I peritrophic matrix as a physical barrier for midgut epithelium invasion by mosquito-borne pathogens in Aedes aegypti. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 8: 701-12. PMID 18627241 DOI: 10.1089/Vbz.2007.0270 |
0.521 |
|
2008 |
Kato N, Sakata T, Breton G, Le Roch KG, Nagle A, Andersen C, Bursulaya B, Henson K, Johnson J, Kumar KA, Marr F, Mason D, McNamara C, Plouffe D, Ramachandran V, et al. Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. Nature Chemical Biology. 4: 347-56. PMID 18454143 DOI: 10.1038/Nchembio.87 |
0.344 |
|
2006 |
Kato N, Mueller CR, Fuchs JF, Wessely V, Lan Q, Christensen BM. Regulatory mechanisms of chitin biosynthesis and roles of chitin in peritrophic matrix formation in the midgut of adult Aedes aegypti. Insect Biochemistry and Molecular Biology. 36: 1-9. PMID 16360944 DOI: 10.1016/J.Ibmb.2005.09.003 |
0.543 |
|
2005 |
Kato N, Mueller CR, Wessely V, Lan Q, Christensen BM. Aedes aegypti phosphohexomutases and uridine diphosphate-hexose pyrophosphorylases: comparison of primary sequences, substrate specificities and temporal transcription. Insect Molecular Biology. 14: 615-24. PMID 16313562 DOI: 10.1111/J.1365-2583.2005.00592.X |
0.488 |
|
2005 |
Kato N, Mueller CR, Wessely V, Lan Q, Christensen BM. Mosquito glucosamine-6-phosphate N-acetyltransferase: cDNA, gene structure and enzyme kinetics. Insect Biochemistry and Molecular Biology. 35: 637-46. PMID 15857769 DOI: 10.1016/J.Ibmb.2005.02.005 |
0.545 |
|
2002 |
Kato N, Dasgupta R, Smartt CT, Christensen BM. Glucosamine:fructose-6-phosphate aminotransferase: gene characterization, chitin biosynthesis and peritrophic matrix formation in Aedes aegypti. Insect Molecular Biology. 11: 207-16. PMID 12000639 DOI: 10.1046/J.1365-2583.2002.00326.X |
0.484 |
|
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