Danny Hung-Chieh Chou, Ph.D. - Publications

Affiliations: 
2007-2011 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
 2011-2014 Chemical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
 2014-2020 Biochemistry University of Utah, Salt Lake City, UT 
 2020- Pediatrics Stanford University, Palo Alto, CA 
Area:
Chemical biology
Website:
https://www.dannychoulab.com

30/67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li W, Jacobsen MT, Park C, Jung JU, Lin NP, Huang PS, Lal RA, Chou DH. A cysteine-specific solubilizing tag strategy enables efficient chemical protein synthesis of difficult targets. Chemical Science. 15: 3214-3222. PMID 38425513 DOI: 10.1039/d3sc06032b  0.329
2024 Zhang YW, Lin NP, Guo X, Szabo-Fresnais N, Ortoleva PJ, Chou DH. Omniligase-1-Mediated Phage-Peptide Library Modification and Insulin Engineering. Acs Chemical Biology. PMID 38266161 DOI: 10.1021/acschembio.3c00685  0.404
2023 Zhang YW, Zheng N, Chou DH. Serine-mediated hydrazone ligation displaying insulin-like peptides on M13 phage pIII. Organic & Biomolecular Chemistry. PMID 37905463 DOI: 10.1039/d3ob01487h  0.545
2023 Meudom R, Zhang Y, VandenBerg MA, Zou L, Zhang YW, Webber MJ, Chou DH. Supramolecular approaches for insulin stabilization without prolonged duration of action. Acta Pharmaceutica Sinica. B. 13: 2281-2290. PMID 37250160 DOI: 10.1016/j.apsb.2023.01.007  0.607
2023 Park C, Zhang Y, Jung JU, Buron LD, Lin NP, Hoeg-Jensen T, Chou DH. Antagonistic Insulin Derivative Suppresses Insulin-Induced Hypoglycemia. Journal of Medicinal Chemistry. PMID 37227951 DOI: 10.1021/acs.jmedchem.3c00280  0.38
2022 Clauss ZS, Meudom R, Su B, VandenBerg MA, Saini SS, Webber MJ, Chou DH, Kramer JR. Supramolecular Protein Stabilization with Zwitterionic Polypeptide-Cucurbit[7]uril Conjugates. Biomacromolecules. 24: 481-488. PMID 36512327 DOI: 10.1021/acs.biomac.2c01319  0.557
2022 Laugesen SH, Chou DH, Safavi-Hemami H. Unconventional insulins from predators and pathogens. Nature Chemical Biology. 18: 688-697. PMID 35761080 DOI: 10.1038/s41589-022-01068-6  0.353
2022 Lin NP, Chou DH. Modifying insulin to improve performance. Science (New York, N.Y.). 376: 1270-1271. PMID 35709283 DOI: 10.1126/science.abq7217  0.3
2022 Lin NP, Zheng N, Purushottam L, Zhang YW, Chou DH. Synthesis and Characterization of Phenylboronic Acid-Modified Insulin With Glucose-Dependent Solubility. Frontiers in Chemistry. 10: 859133. PMID 35372263 DOI: 10.3389/fchem.2022.859133  0.711
2022 Xiong X, Blakely A, Kim JH, Menting JG, Schäfer IB, Schubert HL, Agrawal R, Gutmann T, Delaine C, Zhang YW, Artik GO, Merriman A, Eckert D, Lawrence MC, Coskun Ü, ... ... Chou DH, et al. Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nature Chemical Biology. PMID 35289328 DOI: 10.1038/s41589-022-00981-0  0.392
2021 Disotuar MM, Smith JA, Li J, Alam S, Lin NP, Chou DH. Facile synthesis of insulin fusion derivatives through sortase A ligation. Acta Pharmaceutica Sinica. B. 11: 2719-2725. PMID 34589392 DOI: 10.1016/j.apsb.2020.11.011  0.362
2021 Zheng N, Christensen SB, Dowell C, Purushottam L, Skalicky JJ, McIntosh JM, Chou DH. Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain. Journal of Medicinal Chemistry. PMID 34161094 DOI: 10.1021/acs.jmedchem.1c00802  0.699
2020 Zheng N, Christensen S, Blakely A, Dowell C, Purushottam L, McIntosh JM, Chou DH. Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry. PMID 32597184 DOI: 10.1021/Acs.Jmedchem.0C00613  0.7
2020 Xiong X, Menting JG, Disotuar MM, Smith NA, Delaine CA, Ghabash G, Agrawal R, Wang X, He X, Fisher SJ, MacRaild CA, Norton RS, Gajewiak J, Forbes BE, Smith BJ, ... ... Chou DH, et al. Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nature Structural & Molecular Biology. PMID 32533129 DOI: 10.1038/s41594-020-0460-2  0.312
2020 Xiong X, Menting JG, Disotuar MM, Smith NA, Delaine CA, Ghabash G, Agrawal R, Wang X, He X, Fisher SJ, MacRaild CA, Norton RS, Gajewiak J, Forbes BE, Smith BJ, ... ... Chou DH, et al. A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nature Structural & Molecular Biology. PMID 32483339 DOI: 10.1038/S41594-020-0430-8  0.485
2020 Xiong X, Blakely A, Karra P, VandenBerg MA, Ghabash G, Whitby F, Zhang YW, Webber MJ, Holland WL, Hill CP, Chou DH. Novel four-disulfide insulin analog with high aggregation stability and potency. Chemical Science. 11: 195-200. PMID 32110371 DOI: 10.1039/C9Sc04555D  0.643
2019 Zheng N, Karra P, VandenBerg M, Kim JH, Webber MJ, Holland W, Chou DH. Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analog with Enhanced Stability. Journal of Medicinal Chemistry. PMID 31804076 DOI: 10.1021/Acs.Jmedchem.9B01589  0.673
2019 Disotuar MM, Chen D, Lin NP, Chou DH. Glucose-Responsive Insulin Through Bioconjugation Approaches. Journal of Diabetes Science and Technology. 1932296819854105. PMID 31216874 DOI: 10.1177/1932296819854105  0.458
2018 Jeong MY, Rutter J, Chou DH. Display of single-chain insulin-like peptides on yeast surface. Biochemistry. PMID 30575376 DOI: 10.1021/Acs.Biochem.8B01094  0.386
2018 Disotuar MM, Petersen ME, Nogueira JM, Kay MS, Chou DH. Synthesis of hydrophobic insulin-based peptides using a helping hand strategy. Organic & Biomolecular Chemistry. PMID 29947407 DOI: 10.1039/C8Ob01212A  0.661
2018 Ahorukomeye P, Disotuar MM, Gajewiak J, Karanth S, Watkins M, Robinson SD, Salcedo PF, Smith NA, Smith BJ, Schlegel A, Forbes BE, Olivera B, Chou DH, Safavi-Hemami H. Author response: Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor Elife. DOI: 10.7554/Elife.41574.034  0.374
2017 Chen D, Disotuar MM, Xiong X, Wang Y, Chou DH. Selective N-terminal functionalization of native peptides and proteins. Chemical Science. 8: 2717-2722. PMID 28553506 DOI: 10.1039/C6Sc04744K  0.342
2017 Menting JG, Chou DH, MacRaild CA, Smith NA, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. Venom evolution provides inspiration for development of ultrafast-acting insulins Acta Crystallographica Section a Foundations and Advances. 73: C243-C243. DOI: 10.1107/S2053273317093305  0.328
2016 Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin. Nature Structural & Molecular Biology. PMID 27617429 DOI: 10.1038/nsmb.3292  0.356
2015 Wang Y, Chou DH. A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization. Angewandte Chemie (International Ed. in English). PMID 26189498 DOI: 10.1002/Anie.201503975  0.337
2015 Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dan?ík V, Ciarlo C, Paulk J, et al. Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling. Journal of the American Chemical Society. 137: 7929-34. PMID 26042473 DOI: 10.1021/Jacs.5B04284  0.672
2015 Chou DH, Webber MJ, Tang BC, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proceedings of the National Academy of Sciences of the United States of America. 112: 2401-6. PMID 25675515 DOI: 10.1073/Pnas.1424684112  0.729
2012 Chou DH, Holson EB, Wagner FF, Tang AJ, Maglathlin RL, Lewis TA, Schreiber SL, Wagner BK. Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis. Chemistry & Biology. 19: 669-73. PMID 22726680 DOI: 10.1016/J.Chembiol.2012.05.010  0.646
2011 Chou DH, Duvall JR, Gerard B, Liu H, Pandya BA, Suh BC, Forbeck EM, Faloon P, Wagner BK, Marcaurelle LA. Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis. Acs Medicinal Chemistry Letters. 2: 698-702. PMID 21927648 DOI: 10.1021/Ml200120M  0.62
2010 Chou DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, Wagner BK. Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis. Acs Chemical Biology. 5: 729-34. PMID 20550176 DOI: 10.1021/Cb100129D  0.712
Low-probability matches (unlikely to be authored by this person)
2019 Qiu Y, Agrawal R, Chen D, Zheng N, Durupt G, Kim JH, Fisher SJ, Chou DH. Long‐Lasting Designer Insulin with Glucose‐Dependent Solubility Markedly Reduces Risk of Hypoglycemia Advanced Therapeutics. 2: 1900128. DOI: 10.1002/adtp.201900128  0.261
2022 Jacobsen MT, Spaltenstein P, Giesler RJ, Chou DH, Kay MS. Improved Handling of Peptide Segments Using Side Chain-Based "Helping Hand" Solubilizing Tools. Methods in Molecular Biology (Clifton, N.J.). 2530: 81-107. PMID 35761044 DOI: 10.1007/978-1-0716-2489-0_7  0.196
2017 Wang Y, Bruno B, Cornillie S, Nogueira J, Chen D, Cheatham T, Lim C, Chou D. Application of Thiol-yne/Thiol-ene Reactions for Peptide and Protein Macrocyclizations. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28345248 DOI: 10.1002/Chem.201700572  0.186
2021 Kim H, Perovanovic J, Shakya A, Shen Z, German CN, Ibarra A, Jafek JL, Lin NP, Evavold BD, Chou DH, Jensen PE, He X, Tantin D. Targeting transcriptional coregulator OCA-B/Pou2af1 blocks activated autoreactive T cells in the pancreas and type 1 diabetes. The Journal of Experimental Medicine. 218. PMID 33295943 DOI: 10.1084/jem.20200533  0.175
2022 Sreedhara A, Buecheler J, Brosig S, Chou D, Christian T, Das T, de Jong I, Fast J, Jagannathan B, Morales AM, Moussa EM, Nejadnik MR, Prajapati I, Radwick A, Rahman Y, et al. End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics. The Aaps Journal. 25: 6. PMID 36471030 DOI: 10.1208/s12248-022-00773-3  0.124
2022 Kopp MRG, Grigolato F, Zürcher D, Das TK, Chou D, Wuchner K, Arosio P. Surface-induced protein aggregation and particle formation in biologics: current understanding of mechanisms, detection and mitigation strategies. Journal of Pharmaceutical Sciences. PMID 36223809 DOI: 10.1016/j.xphs.2022.10.009  0.108
2023 Morales AM, Sreedhara A, Buecheler J, Brosig S, Chou D, Christian T, Das T, de Jong I, Fast J, Jagannathan B, Moussa EM, Nejadnik MR, Prajapati I, Radwick A, Rahman Y, et al. Correction: End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics. The Aaps Journal. 25: 15. PMID 36631711 DOI: 10.1208/s12248-023-00780-y  0.107
2007 Johnston K, Johnston L, Clark W, Chou D. A multidisciplinary approach to the diagnosis and management of chronic pain associated with pelvic venous incompetence. Journal of Minimally Invasive Gynecology. 14: 2-3. PMID 17218220 DOI: 10.1016/j.jmig.2006.07.016  0.09
1996 Chou DH, Lee W, McCulloch CA. TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 156: 4354-62. PMID 8666807  0.087
2010 Singh SK, Afonina N, Awwad M, Bechtold-Peters K, Blue JT, Chou D, Cromwell M, Krause HJ, Mahler HC, Meyer BK, Narhi L, Nesta DP, Spitznagel T. An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics. Journal of Pharmaceutical Sciences. 99: 3302-21. PMID 20310025 DOI: 10.1002/jps.22097  0.058
2021 Listijono DR, Rosen DMB, Choi S, Bukhari M, Cario GM, Chou D. Cultivating the Apprentice-Mentor Model for Minimally Invasive Gynaecology in the Era of Surgically Scarce Training: A Case Report of Laparoscopic Cornuostomy for Interstitial Ectopic Pregnancy by a Trainee. Case Reports in Obstetrics and Gynecology. 2021: 5560309. PMID 33747585 DOI: 10.1155/2021/5560309  0.046
2008 Rosen DMB, Shukla A, Cario GM, Carlton MA, Chou D. Is Hysterectomy Necessary for Laparoscopic Pelvic Floor Repair? A Prospective Study Journal of Minimally Invasive Gynecology. 15: 729-734. PMID 18971137 DOI: 10.1016/j.jmig.2008.08.010  0.045
2018 Saar TD, Pacquée S, Conrad DH, Sarofim M, Rosnay P, Rosen D, Cario G, Chou D. Endometriosis Involving the Sciatic Nerve: A Case Report of Isolated Endometriosis of the Sciatic Nerve and Review of the Literature. Gynecology and Minimally Invasive Therapy. 7: 81-85. PMID 30254944 DOI: 10.4103/GMIT.GMIT_24_18  0.044
2005 Elkington N, Cario G, Rosen D, Carlton M, Chou D. Total laparoscopic hysterectomy: a tried and tested technique. Journal of Minimally Invasive Gynecology. 12: 267-74. PMID 15922986 DOI: 10.1016/j.jmig.2005.03.005  0.042
2018 Pacquée S, Conrad DH, Saar TD, Rosen D, Cario G, Chou D, Smet ME. Surgical Management of Complete Procidentia in a Female Patient with Bladder Exstrophy-epispadias Complex: Case Report and Literature Review. Gynecology and Minimally Invasive Therapy. 7: 127-129. PMID 30254955 DOI: 10.4103/GMIT.GMIT_14_18  0.041
2010 Kwik M, O'Neill A, Hamani Y, Chapman M, Chou D. Laparoscopic ovarian transposition with potential preservation of natural fertility. Journal of Minimally Invasive Gynecology. 17: 411-2. PMID 20621003 DOI: 10.1016/j.jmig.2009.07.002  0.039
1993 Zhang DH, Chou DH, Pan WS. [Pleural mesothelioma: a clinicopathologic study of 42 cases]. Zhonghua Nei Ke Za Zhi. 32: 587-90. PMID 8112139  0.035
2014 McKenna JB, Kanade T, Choi S, Tsai BP, Rosen DM, Cario GM, Chou D. The Sydney Contained In Bag Morcellation technique. Journal of Minimally Invasive Gynecology. 21: 984-5. PMID 25048565 DOI: 10.1016/j.jmig.2014.07.007  0.035
2012 Aust T, Reyftmann L, Rosen D, Cario G, Chou D. Anterior approach to laparoscopic uterine artery ligation. Journal of Minimally Invasive Gynecology. 18: 792-5. PMID 22024265 DOI: 10.1016/j.jmig.2011.07.008  0.034
2021 De Silva P, Daniels S, Bukhari ME, Choi S, Liew A, Rosen DMB, Conrad D, Cario GM, Chou D. Superior Hypogastric Plexus Nerve Block in Minimally Invasive Gynecology: a Randomised Controlled Trial. Journal of Minimally Invasive Gynecology. PMID 34197956 DOI: 10.1016/j.jmig.2021.06.017  0.032
2014 Kanade TT, McKenna JB, Choi S, Tsai BP, Rosen DM, Cario GM, Chou D. Sydney contained in bag morcellation for laparoscopic myomectomy. Journal of Minimally Invasive Gynecology. 21: 981. PMID 25048568 DOI: 10.1016/j.jmig.2014.07.005  0.031
2006 Elkington NM, Chou D. A review of total laparoscopic hysterectomy: role, techniques and complications. Current Opinion in Obstetrics & Gynecology. 18: 380-4. PMID 16794416 DOI: 10.1097/01.gco.0000233930.21307.5a  0.025
2018 Conrad DH, Saar TD, Pacquée S, Sarofim M, Rosen D, Cario G, Chou D. Laparoscopic Myomectomy of a 4.2 kg Fibroid with Assistance of a Minilaparotomy. Gynecology and Minimally Invasive Therapy. 7: 130-132. PMID 30254956 DOI: 10.4103/GMIT.GMIT_13_18  0.024
2023 Robertson J, Abbott J, Corbett-Burns S, Bukhari M, Perera S, Kalantan A, Sarofim M, Chou R, Cario G, Rosen D, Choi S, Wynn-Williams M, Condous G, Chou D. Treatment of rectosigmoid endometriosis by laparoscopic reverse submucosal dissection (LRSD): The Sydney partial thickness discoid excision technique. The Australian & New Zealand Journal of Obstetrics & Gynaecology. PMID 37905841 DOI: 10.1111/ajo.13762  0.024
2021 Chou D, Perera S, Bukhari M, Al-Shamari M, Cario APG, Rosen D, Choi S, Med JAB, Wynn-Williams M, Condous G. Rectal Shaving for Bowel Endometriosis by Laparoscopic Reverse Submucosal Dissection (LRSD) for Easier, Safer and More Complete Excision of Disease. Journal of Minimally Invasive Gynecology. PMID 34023519 DOI: 10.1016/j.jmig.2021.05.011  0.023
2004 Gui JH, Liu JY, Jia LT, Chou DH, Yu WZ, He J. [The chromosomal location of AD7C-NTP gene and the prediction of transmembrane domains of its deduced protein]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 20: 604-7. PMID 15367359  0.023
2019 Conrad DH, Pacquee S, Saar TD, Walsh C, Chou D, Rosen D, Cario GM. Long-term patient-reported outcomes after laparoscopic Burch colposuspension. The Australian & New Zealand Journal of Obstetrics & Gynaecology. PMID 31514249 DOI: 10.1111/ajo.13048  0.022
2007 Johnston K, Rosen D, Cario G, Chou D, Carlton M, Cooper M, Reid G. Major complications arising from 1265 operative laparoscopic cases: a prospective review from a single center. Journal of Minimally Invasive Gynecology. 14: 339-44. PMID 17478366 DOI: 10.1016/j.jmig.2006.12.003  0.018
2010 Rosen DM, Hamani Y, Cario GM, Chou D. Uterine perfusion following laparoscopic clipping of uterine arteries at myomectomy. The Australian & New Zealand Journal of Obstetrics & Gynaecology. 49: 559-60. PMID 19780746 DOI: 10.1111/j.1479-828X.2009.01046.x  0.018
2021 Rosen DMB, Conrad DH, Saar TD, Cario GM, Chou D, Bukhari M. Removing the large uterus without morcellation - The Colpo-V incision for specimen extraction at hysterectomy. The Australian & New Zealand Journal of Obstetrics & Gynaecology. PMID 34097304 DOI: 10.1111/ajo.13395  0.017
2020 Leonardi M, Espada M, Choi S, Chou D, Chang T, Smith C, Rowan K, Condous G. Transvaginal Ultrasound Can Accurately Predict the American Society of Reproductive Medicine (ASRM) Stage of Endometriosis Assigned at Laparoscopy. Journal of Minimally Invasive Gynecology. PMID 32126302 DOI: 10.1016/j.jmig.2020.02.014  0.015
2022 Chou R, Robertson J, Bukhari M, Chou D. Uterine Teratoma (Dermoid cyst) Presenting as an Endometrial Polyp. Gynecology and Minimally Invasive Therapy. 11: 256-257. PMID 36660324 DOI: 10.4103/gmit.gmit_107_21  0.01
2018 Leonardi M, Reid S, Lu C, Gerges B, Chang T, Rombauts L, Healey M, Chou D, Choi S, Al-Mashat D, Ahmed S, Magotti R, Nader R, Adno A, Condous G. Diagnostic Accuracy and Reproducibility of Predicting Cul-de-Sac Obliteration by General Gynaecologists and Minimally Invasive Gynaecologic Surgeons. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'Obstetrique Et Gynecologie Du Canada : Jogc. PMID 30361156 DOI: 10.1016/j.jogc.2018.06.023  0.01
2010 Lee HY, Chou D, Pang SM, Thirumoorthy T. Acute generalized exanthematous pustulosis: analysis of cases managed in a tertiary hospital in Singapore. International Journal of Dermatology. 49: 507-12. PMID 20534083 DOI: 10.1111/j.1365-4632.2010.04313.x  0.01
2006 Shukla A, Johnston KM, Aslan P, Chou D. Infiltrative vesical and ureteral endometriosis: two different points of view. Journal of Minimally Invasive Gynecology. 13: 497-8. PMID 17097567 DOI: 10.1016/j.jmig.2006.04.012  0.01
1994 Zheng RH, Chou DH, Shi MX. [Hamartoma of the lung: an analysis of 24 cases]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases. 17: 86-7, 126. PMID 7994773  0.01
1981 Chou DH. [Nursing care of a 6-year-old boy in ICU after open heart surgery]. Hu Li Za Zhi the Journal of Nursing. 28: 30-5. PMID 6912286  0.01
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