Sharon L. Campbell - Publications

Affiliations: 
Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Ras and Rho GTPases, Their Modulators and Effectors
Website:
http://www.med.unc.edu/biochem/campbell

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Arrington ME, Temple B, Schaefer A, Campbell SL. The molecular basis for immune dysregulation by the hyper-activated E62K mutant of the GTPase RAC2. The Journal of Biological Chemistry. PMID 32636302 DOI: 10.1074/jbc.RA120.012915  1
2019 Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, ... ... Campbell SL, et al. Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. Cancer Discovery. PMID 31649109 DOI: 10.1158/2159-8290.CD-19-1006  1
2019 Dohlman HG, Campbell SL. Regulation of large and small G proteins by ubiquitination. The Journal of Biological Chemistry. PMID 31645437 DOI: 10.1074/jbc.REV119.011068  1
2019 Yoshino H, Yin G, Kawaguchi R, Popov KI, Temple B, Sasaki M, Kofuji S, Wolfe K, Kofuji K, Okumura K, Randhawa J, Malhotra A, Majd N, Ikeda Y, Shimada H, ... ... Campbell SL, et al. Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan. Plos One. 14: e0224443. PMID 31639175 DOI: 10.1371/journal.pone.0224443  1
2019 Lee HT, Sharek L, O'Brien ET, Urbina FL, Gupton SL, Superfine R, Burridge K, Campbell SL. Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction. Plos One. 14: e0221962. PMID 31483833 DOI: 10.1371/journal.pone.0221962  1
2019 Krokhotin A, Sarker M, Sevilla EA, Costantini LM, Griffith JD, Campbell SL, Dokholyan NV. Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences. Structure (London, England : 1993). PMID 31422909 DOI: 10.1016/j.str.2019.07.013  1
2019 Yoshino H, Yin G, Kawaguchi R, Popov KI, Temple B, Sasaki M, Kofuji S, Wolfe K, Kofuji K, Okumura K, Randhawa J, Malhotra A, Majd N, Ikeda Y, Shimada H, ... ... Campbell SL, et al. Identification of lysine methylation in the core GTPase domain by GoMADScan. Plos One. 14: e0219436. PMID 31390367 DOI: 10.1371/journal.pone.0219436  1
2019 Sarker M, Lee HT, Mei L, Krokhotin A, de Los Reyes SE, Yen L, Costantini LM, Griffith J, Dokholyan NV, Alushin GM, Campbell SL. Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. Journal of Molecular Biology. PMID 30844403 DOI: 10.1016/j.jmb.2019.02.024  1
2019 Zhu C, Dukhovlinova E, Council O, Ping L, Faison EM, Prabhu SS, Potter EL, Upton SL, Yin G, Fay JM, Kincer LP, Spielvogel E, Campbell SL, Benhabbour SR, Ke H, et al. Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies. Nature Communications. 10: 948. PMID 30814513 DOI: 10.1038/s41467-019-08876-w  1
2017 Shellhammer JP, Morin-Kensicki E, Matson JP, Yin G, Isom DG, Campbell SL, Mohney RP, Dohlman HG. Amino acid metabolites that regulate G protein signaling during osmotic stress. Plos Genetics. 13: e1006829. PMID 28558063 DOI: 10.1371/journal.pgen.1006829  1
2017 Yin G, Kistler S, George SD, Kuhlmann N, Garvey L, Huynh M, Bagni RK, Lammers M, Der CJ, Campbell SL. A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation. The Journal of Biological Chemistry. PMID 28154176 DOI: 10.1074/jbc.M116.762435  1
2016 Thompson PM, Ramachandran S, Case LB, Tolbert CE, Tandon A, Pershad M, Dokholyan NV, Waterman CM, Campbell SL. A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization. Structure (London, England : 1993). PMID 28089450 DOI: 10.1016/j.str.2016.12.002  1
2016 Kim LY, Thompson PM, Lee HT, Pershad M, Campbell SL, Alushin GM. The Structural Basis of Actin Organization by Vinculin and Metavinculin. Journal of Molecular Biology. 428: 10-25. PMID 26493222 DOI: 10.1016/j.jmb.2015.09.031  1
2016 Huynh MV, Campbell SL. Getting a Handle on RAS-targeted Therapies: Cysteine Directed Inhibitors. Mini Reviews in Medicinal Chemistry. 16: 383-90. PMID 26423694  1
2015 Case LB, Baird MA, Shtengel G, Campbell SL, Hess HF, Davidson MW, Waterman CM. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nature Cell Biology. 17: 880-92. PMID 26053221 DOI: 10.1038/ncb3180  1
2015 Thompson PM, Beck MR, Campbell SL. Protein-protein interaction analysis by nuclear magnetic resonance spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 1278: 267-79. PMID 25859955 DOI: 10.1007/978-1-4939-2425-7_16  1
2015 Wall SB, Oh JY, Mitchell L, Laube AH, Campbell SL, Renfrow MB, Landar A. Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J2 analog. Redox Biology. 4: 346-54. PMID 25677088 DOI: 10.1016/j.redox.2015.01.016  1
2015 Hobbs GA, Mitchell LE, Arrington ME, Gunawardena HP, DeCristo MJ, Loeser RF, Chen X, Cox AD, Campbell SL. Redox regulation of Rac1 by thiol oxidation. Free Radical Biology & Medicine. 79: 237-50. PMID 25289457 DOI: 10.1016/j.freeradbiomed.2014.09.027  1
2014 Burd CE, Liu W, Huynh MV, Waqas MA, Gillahan JE, Clark KS, Fu K, Martin BL, Jeck WR, Souroullas GP, Darr DB, Zedek DC, Miley MJ, Baguley BC, Campbell SL, et al. Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma. Cancer Discovery. 4: 1418-29. PMID 25252692 DOI: 10.1158/2159-8290.CD-14-0729  1
2014 Tolbert CE, Thompson PM, Superfine R, Burridge K, Campbell SL. Phosphorylation at Y1065 in vinculin mediates actin bundling, cell spreading, and mechanical responses to force. Biochemistry. 53: 5526-36. PMID 25115937 DOI: 10.1021/bi500678x  1
2014 Hobbs GA, Zhou B, Cox AD, Campbell SL. Rho GTPases, oxidation, and cell redox control. Small Gtpases. 5: e28579. PMID 24809833 DOI: 10.4161/sgtp.28579  1
2014 Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM. Copper is required for oncogenic BRAF signalling and tumorigenesis. Nature. 509: 492-6. PMID 24717435 DOI: 10.1038/nature13180  1
2014 Thompson PM, Tolbert CE, Shen K, Kota P, Palmer SM, Plevock KM, Orlova A, Galkin VE, Burridge K, Egelman EH, Dokholyan NV, Superfine R, Campbell SL. Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties. Structure (London, England : 1993). 22: 697-706. PMID 24685146 DOI: 10.1016/j.str.2014.03.002  1
2014 Hobbs GA, Gunawardena HP, Campbell SL. Biophysical and proteomic characterization strategies for cysteine modifications in Ras GTPases. Methods in Molecular Biology (Clifton, N.J.). 1120: 75-96. PMID 24470020 DOI: 10.1007/978-1-62703-791-4_6  1
2013 Baker R, Wilkerson EM, Sumita K, Isom DG, Sasaki AT, Dohlman HG, Campbell SL. Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination. The Journal of Biological Chemistry. 288: 36856-62. PMID 24247240 DOI: 10.1074/jbc.C113.525691  1
2013 Hobbs GA, Gunawardena HP, Baker R, Campbell SL. Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function. Small Gtpases. 4: 186-92. PMID 24030601 DOI: 10.4161/sgtp.26270  1
2013 Thievessen I, Thompson PM, Berlemont S, Plevock KM, Plotnikov SV, Zemljic-Harpf A, Ross RS, Davidson MW, Danuser G, Campbell SL, Waterman CM. Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. The Journal of Cell Biology. 202: 163-77. PMID 23836933 DOI: 10.1083/jcb.201303129  1
2013 Beck MR, Dixon RD, Goicoechea SM, Murphy GS, Brungardt JG, Beam MT, Srinath P, Patel J, Mohiuddin J, Otey CA, Campbell SL. Structure and function of palladin's actin binding domain. Journal of Molecular Biology. 425: 3325-37. PMID 23806659 DOI: 10.1016/j.jmb.2013.06.016  1
2013 Thompson PM, Tolbert CE, Campbell SL. Vinculin and metavinculin: oligomerization and interactions with F-actin. Febs Letters. 587: 1220-9. PMID 23466368 DOI: 10.1016/j.febslet.2013.02.042  1
2013 Tolbert CE, Burridge K, Campbell SL. Vinculin regulation of F-actin bundle formation: what does it mean for the cell? Cell Adhesion & Migration. 7: 219-25. PMID 23307141 DOI: 10.4161/cam.23184  1
2013 Baker R, Lewis SM, Sasaki AT, Wilkerson EM, Locasale JW, Cantley LC, Kuhlman B, Dohlman HG, Campbell SL. Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function. Nature Structural & Molecular Biology. 20: 46-52. PMID 23178454 DOI: 10.1038/nsmb.2430  1
2013 Hobbs GA, Bonini MG, Gunawardena HP, Chen X, Campbell SL. Glutathiolated Ras: characterization and implications for Ras activation. Free Radical Biology & Medicine. 57: 221-9. PMID 23123410 DOI: 10.1016/j.freeradbiomed.2012.10.531  1
2013 Mitchell L, Hobbs GA, Aghajanian A, Campbell SL. Redox regulation of Ras and Rho GTPases: mechanism and function. Antioxidants & Redox Signaling. 18: 250-8. PMID 22657737 DOI: 10.1089/ars.2012.4687  1
2012 Vigil D, Kim TY, Plachco A, Garton AJ, Castaldo L, Pachter JA, Dong H, Chen X, Tokar B, Campbell SL, Der CJ. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Research. 72: 5338-47. PMID 22942252 DOI: 10.1158/0008-5472.CAN-11-2373  1
2012 Davis MF, Zhou L, Ehrenshaft M, Ranguelova K, Gunawardena HP, Chen X, Bonini MG, Mason RP, Campbell SL. Detection of Ras GTPase protein radicals through immuno-spin trapping. Free Radical Biology & Medicine. 53: 1339-45. PMID 22819983 DOI: 10.1016/j.freeradbiomed.2012.07.009  1
2012 Cable J, Prutzman K, Gunawardena HP, Schaller MD, Chen X, Campbell SL. In vitro phosphorylation of the focal adhesion targeting domain of focal adhesion kinase by Src kinase. Biochemistry. 51: 2213-23. PMID 22372511 DOI: 10.1021/bi300123a  1
2011 Shen K, Tolbert CE, Guilluy C, Swaminathan VS, Berginski ME, Burridge K, Superfine R, Campbell SL. The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties. The Journal of Biological Chemistry. 286: 45103-15. PMID 22052910 DOI: 10.1074/jbc.M111.244293  1
2011 Beck MR, Otey CA, Campbell SL. Structural characterization of the interactions between palladin and α-actinin. Journal of Molecular Biology. 413: 712-25. PMID 21925511 DOI: 10.1016/j.jmb.2011.08.059  1
2011 Bhattacharyya D, Ramachandran S, Sharma S, Pathmasiri W, King CL, Baskerville-Abraham I, Boysen G, Swenberg JA, Campbell SL, Dokholyan NV, Chaney SG. Flanking bases influence the nature of DNA distortion by platinum 1,2-intrastrand (GG) cross-links. Plos One. 6: e23582. PMID 21853154 DOI: 10.1371/journal.pone.0023582  1
2011 Davis MF, Vigil D, Campbell SL. Regulation of Ras proteins by reactive nitrogen species. Free Radical Biology & Medicine. 51: 565-75. PMID 21616138 DOI: 10.1016/j.freeradbiomed.2011.05.003  1
2011 Esna Ashari A, Nikoukhah R, Campbell SL. Auxiliary signal design for robust active fault detection of linear discrete-time systems Automatica. 47: 1887-1895. DOI: 10.1016/j.automatica.2011.06.009  0.01
2010 Vigil D, Martin TD, Williams F, Yeh JJ, Campbell SL, Der CJ. Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms. The Journal of Biological Chemistry. 285: 34729-40. PMID 20801877 DOI: 10.1074/jbc.M110.116756  1
2009 Aghajanian A, Wittchen ES, Campbell SL, Burridge K. Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. Plos One. 4: e8045. PMID 19956681 DOI: 10.1371/journal.pone.0008045  1
2009 Palmer SM, Playford MP, Craig SW, Schaller MD, Campbell SL. Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini. The Journal of Biological Chemistry. 284: 7223-31. PMID 19110481 DOI: 10.1074/jbc.M807842200  1
2008 Palmer SM, Campbell SL. Backbone 1H, 13C, and 15N NMR assignments of the tail domain of vinculin. Biomolecular Nmr Assignments. 2: 69-71. PMID 19636928 DOI: 10.1007/s12104-008-9087-7  1
2008 Dixon RD, Campbell SL. 1H, 15N, and 13C NMR chemical shift assignments for the Ig3 domain of palladin. Biomolecular Nmr Assignments. 2: 51-3. PMID 19636923 DOI: 10.1007/s12104-008-9082-z  1
2008 Palmer SM, Schaller MD, Campbell SL. Vinculin tail conformation and self-association is independent of pH and H906 protonation. Biochemistry. 47: 12467-75. PMID 18980387 DOI: 10.1021/bi801764a  1
2008 Dixon RD, Arneman DK, Rachlin AS, Sundaresan NR, Costello MJ, Campbell SL, Otey CA. Palladin is an actin cross-linking protein that uses immunoglobulin-like domains to bind filamentous actin. The Journal of Biological Chemistry. 283: 6222-31. PMID 18180288 DOI: 10.1074/jbc.M707694200  1
2008 Scheswohl DM, Harrell JR, Rajfur Z, Gao G, Campbell SL, Schaller MD. Multiple paxillin binding sites regulate FAK function. Journal of Molecular Signaling. 3: 1. PMID 18171471 DOI: 10.1186/1750-2187-3-1  1
2008 Dixon RDS, Arneman DK, Rachlin AS, Sundaresan NR, Costello MJ, Campbell SL, Otey CA. Palladin is an actin cross-linking protein that uses immunoglobulin-like domains to bind filamentous actin (Journal of Biological Chemistry (2008) 283 (6222-6231)) Journal of Biological Chemistry. 283: 27344.  1
2007 Raines KW, Bonini MG, Campbell SL. Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases. Cardiovascular Research. 75: 229-39. PMID 17559822 DOI: 10.1016/j.cardiores.2007.04.013  1
2007 Chen Y, Campbell SL, Dokholyan NV. Deciphering protein dynamics from NMR data using explicit structure sampling and selection. Biophysical Journal. 93: 2300-6. PMID 17557784 DOI: 10.1529/biophysj.107.104174  1
2007 Wu Y, Bhattacharyya D, King CL, Baskerville-Abraham I, Huh SH, Boysen G, Swenberg JA, Temple B, Campbell SL, Chaney SG. Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link. Biochemistry. 46: 6477-87. PMID 17497831 DOI: 10.1021/bi062291f  1
2006 Campbell S. Bioidentical hormones. Achieving the perfect fit Advance For Nurse Practitioners. 14: 25-29; quiz 30. PMID 2006090506  1
2006 Heo J, Raines KW, Mocanu V, Campbell SL. Redox regulation of RhoA. Biochemistry. 45: 14481-9. PMID 17128987 DOI: 10.1021/bi0610101  1
2006 Heo J, Campbell SL. Ras regulation by reactive oxygen and nitrogen species. Biochemistry. 45: 2200-10. PMID 16475808 DOI: 10.1021/bi051872m  1
2006 Ding F, Prutzman KC, Campbell SL, Dokholyan NV. Topological determinants of protein domain swapping. Structure (London, England : 1993). 14: 5-14. PMID 16407060 DOI: 10.1016/j.str.2005.09.008  1
2005 Heo J, Campbell SL. Mechanism of redox-mediated guanine nucleotide exchange on redox-active Rho GTPases. The Journal of Biological Chemistry. 280: 31003-10. PMID 15994296 DOI: 10.1074/jbc.M504768200  1
2005 Heo J, Thapar R, Campbell SL. Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors. Biochemistry. 44: 6573-85. PMID 15850391 DOI: 10.1021/bi047443q  1
2005 Heo J, Prutzman KC, Mocanu V, Campbell SL. Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation. Journal of Molecular Biology. 346: 1423-40. PMID 15713491 DOI: 10.1016/j.jmb.2004.12.050  1
2005 Heo J, Campbell SL. Superoxide anion radical modulates the activity of Ras and Ras-related GTPases by a radical-based mechanism similar to that of nitric oxide. The Journal of Biological Chemistry. 280: 12438-45. PMID 15684418 DOI: 10.1074/jbc.M414282200  1
2005 Hekman M, Fischer A, Wennogle LP, Wang YK, Campbell SL, Rapp UR. Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation. Febs Letters. 579: 464-8. PMID 15642359 DOI: 10.1016/j.febslet.2004.11.105  0.01
2005 Chaney SG, Campbell SL, Bassett E, Wu Y. Recognition and processing of cisplatin- and oxaliplatin-DNA adducts. Critical Reviews in Oncology/Hematology. 53: 3-11. PMID 15607931 DOI: 10.1016/j.critrevonc.2004.08.008  1
2004 Dixon RD, Chen Y, Ding F, Khare SD, Prutzman KC, Schaller MD, Campbell SL, Dokholyan NV. New insights into FAK signaling and localization based on detection of a FAT domain folding intermediate. Structure (London, England : 1993). 12: 2161-71. PMID 15576030 DOI: 10.1016/j.str.2004.09.011  1
2004 Thapar R, Williams JG, Campbell SL. NMR characterization of full-length farnesylated and non-farnesylated H-Ras and its implications for Raf activation. Journal of Molecular Biology. 343: 1391-408. PMID 15491620 DOI: 10.1016/j.jmb.2004.08.106  1
2004 Chaney SG, Campbell SL, Temple B, Bassett E, Wu Y, Faldu M. Protein interactions with platinum-DNA adducts: from structure to function. Journal of Inorganic Biochemistry. 98: 1551-9. PMID 15458816 DOI: 10.1016/j.jinorgbio.2004.04.024  1
2004 Wu Y, Pradhan P, Havener J, Boysen G, Swenberg JA, Campbell SL, Chaney SG. NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex. Journal of Molecular Biology. 341: 1251-69. PMID 15321720 DOI: 10.1016/j.jmb.2004.06.066  1
2004 Heo J, Gao G, Campbell SL. pH-dependent perturbation of Ras-guanine nucleotide interactions and Ras guanine nucleotide exchange. Biochemistry. 43: 10102-11. PMID 15287738 DOI: 10.1021/bi035704a  1
2004 Prutzman KC, Gao G, King ML, Iyer VV, Mueller GA, Schaller MD, Campbell SL. The focal adhesion targeting domain of focal adhesion kinase contains a hinge region that modulates tyrosine 926 phosphorylation. Structure (London, England : 1993). 12: 881-91. PMID 15130480 DOI: 10.1016/j.str.2004.02.028  1
2004 Solski PA, Wilder RS, Rossman KL, Sondek J, Cox AD, Campbell SL, Der CJ. Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation. The Journal of Biological Chemistry. 279: 25226-33. PMID 15073184 DOI: 10.1074/jbc.M313792200  1
2004 Gao G, Williams JG, Campbell SL. Protein-protein interaction analysis by nuclear magnetic resonance spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 261: 79-92. PMID 15064450 DOI: 10.1385/1-59259-762-9:079  1
2004 Karnoub AE, Symons M, Campbell SL, Der CJ. Molecular basis for Rho GTPase signaling specificity. Breast Cancer Research and Treatment. 84: 61-71. PMID 14999155 DOI: 10.1023/B:BREA.0000018427.84929.5c  1
2004 Heo J, Campbell SL. Mechanism of p21Ras S-nitrosylation and kinetics of nitric oxide-mediated guanine nucleotide exchange. Biochemistry. 43: 2314-22. PMID 14979728 DOI: 10.1021/bi035275g  1
2004 Gao G, Prutzman KC, King ML, Scheswohl DM, DeRose EF, London RE, Schaller MD, Campbell SL. NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model. The Journal of Biological Chemistry. 279: 8441-51. PMID 14662767 DOI: 10.1074/jbc.M309808200  1
2003 Thapar R, Moore CD, Campbell SL. Backbone 1H, 13C, and 15N resonance assignments for the 21 kDa GTPase Rac1 complexed to GDP and Mg2+. Journal of Biomolecular Nmr. 27: 87-8. PMID 12878844  1
2003 Williams JG, Pappu K, Campbell SL. Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange. Proceedings of the National Academy of Sciences of the United States of America. 100: 6376-81. PMID 12740440 DOI: 10.1073/pnas.1037299100  1
2003 Fuentes EJ, Karnoub AE, Booden MA, Der CJ, Campbell SL. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation. The Journal of Biological Chemistry. 278: 21188-96. PMID 12637530 DOI: 10.1074/jbc.M211792200  1
2002 Booden MA, Campbell SL, Der CJ. Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation. Molecular and Cellular Biology. 22: 2487-97. PMID 11909943  1
2002 Thapar R, Karnoub AE, Campbell SL. Structural and biophysical insights into the role of the insert region in Rac1 function. Biochemistry. 41: 3875-83. PMID 11900529  1
2002 Rossman KL, Worthylake DK, Snyder JT, Siderovski DP, Campbell SL, Sondek J. A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. The Embo Journal. 21: 1315-26. PMID 11889037 DOI: 10.1093/emboj/21.6.1315  1
2002 Lambert JM, Karnoub AE, Graves LM, Campbell SL, Der CJ. Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation. The Journal of Biological Chemistry. 277: 4770-7. PMID 11713255 DOI: 10.1074/jbc.M109379200  1
2001 Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors. Nature Structural Biology. 8: 1037-41. PMID 11685227 DOI: 10.1038/nsb719  1
2001 Karnoub AE, Der CJ, Campbell SL. The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Molecular and Cellular Biology. 21: 2847-57. PMID 11283263 DOI: 10.1128/MCB.21.8.2847-2857.2001  1
2000 Rossman KL, Campbell SL. Bacterial expressed DH and DH/PH domains. Methods in Enzymology. 325: 25-38. PMID 11036589  1
2000 Drugan JK, Rogers-Graham K, Gilmer T, Campbell S, Clark GJ. The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain Journal of Biological Chemistry. 275: 35021-35027. PMID 10954709 DOI: 10.1074/jbc.M004386200  1
2000 Williams JG, Drugan JK, Yi GS, Clark GJ, Der CJ, Campbell SL. Elucidation of binding determinants and functional consequences of Ras/Raf-cysteine-rich domain interactions. The Journal of Biological Chemistry. 275: 22172-9. PMID 10777480 DOI: 10.1074/jbc.M000397200  1
2000 Abe K, Rossman KL, Liu B, Ritola KD, Chiang D, Campbell SL, Burridge K, Der CJ. Vav2 is an activator of Cdc42, Rac1, and RhoA. The Journal of Biological Chemistry. 275: 10141-9. PMID 10744696 DOI: 10.1074/jbc.275.14.10141  1
1999 Whitehead IP, Lambert QT, Glaven JA, Abe K, Rossman KL, Mahon GM, Trzaskos JM, Kay R, Campbell SL, Der CJ. Dependence of Dbl and Dbs transformation on MEK and NF-κB activation Molecular and Cellular Biology. 19: 7759-7770. PMID 10523665 DOI: 10.1128/MCB.19.11.7759  1
1999 Graham SM, Oldham SM, Martin CB, Drugan JK, Zohn IE, Campbell S, Der CJ. TC21 and Ras share indistinguishable transforming and differentiating activities. Oncogene. 18: 2107-16. PMID 10321735 DOI: 10.1038/sj.onc.1202517  1
1998 Zohn IM, Campbell SL, Khosravi-Far R, Rossman KL, Der CJ. Rho family proteins and Ras transformation: The RHOad less traveled gets congested Oncogene. 17: 1415-1438. PMID 9779988 DOI: 10.1038/sj.onc.1202181  1
1998 Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ. Increasing complexity of Ras signaling Oncogene. 17: 1395-1413. PMID 9779987 DOI: 10.1038/sj.onc.1202174  1
1998 Winkler DG, Cutler RE, Drugan JK, Campbell S, Morrison DK, Cooper JA. Identification of residues in the cysteine-rich domain of Raf-1 that control Ras binding and Raf-1 activity Journal of Biological Chemistry. 273: 21578-21584. PMID 9705288 DOI: 10.1074/jbc.273.34.21578  1
1997 Khosravi-Far R, Campbell S, Rossman KL, Der CJ. Increasing complexity of ras signal transduction: Involvement of rho family proteins Advances in Cancer Research. 72: 57-107. PMID 9338074 DOI: 10.1016/S0065-230X(08)60700-9  1
1997 Clark GJ, Drugan JK, Rossman KL, Carpenter JW, Rogers-Graham K, Fu H, Der CJ, Campbell SL. 14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain. The Journal of Biological Chemistry. 272: 20990-3. PMID 9261098 DOI: 10.1074/jbc.272.34.20990  1
1997 Mott HR, Carpenter JW, Campbell SL. Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation. Biochemistry. 36: 3640-4. PMID 9132016 DOI: 10.1021/bi962790o  1
1997 Whitehead IP, Campbell S, Rossman KL, Der CJ. Dbl family proteins Biochimica Et Biophysica Acta - Reviews On Cancer. 1332: F1-F23. PMID 9061011 DOI: 10.1016/S0304-419X(96)00040-6  1
1997 Lander HM, Hajjar DP, Hempstead BL, Mirza UA, Chait BT, Campbell S, Quilliam LA. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. The Journal of Biological Chemistry. 272: 4323-6. PMID 9020151 DOI: 10.1074/jbc.272.7.4323  1
1996 Mott HR, Carpenter JW, Zhong S, Ghosh S, Bell RM, Campbell SL. The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site. Proceedings of the National Academy of Sciences of the United States of America. 93: 8312-7. PMID 8710867 DOI: 10.1073/pnas.93.16.8312  1
1996 Clark GJ, Drugan JK, Terrell RS, Bradham C, Der CJ, Bell RM, Campbell S. Peptides containing a consensus Ras binding sequence from Raf-1 and the GTPase activating protein NF1 inhibit Ras function Proceedings of the National Academy of Sciences of the United States of America. 93: 1577-1581. PMID 8643674 DOI: 10.1073/pnas.93.4.1577  1
1996 Quilliam LA, Hisaka MM, Zhong S, Lowry A, Mosteller RD, Han J, Drugan JK, Broek D, Campbell SL, Der CJ. Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. The Journal of Biological Chemistry. 271: 11076-82. PMID 8626650 DOI: 10.1074/jbc.271.19.11076  1
1996 Drugan JK, Khosravi-Far R, White MA, Der CJ, Sung YJ, Hwang YW, Campbell SL. Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation. The Journal of Biological Chemistry. 271: 233-7. PMID 8550565 DOI: 10.1074/jbc.271.1.233  1
1995 Campbell-Burk SL, Carpenter JW. Refolding and purification of Ras proteins. Methods in Enzymology. 255: 3-13. PMID 8524114  1
1994 Kraulis PJ, Domaille PJ, Campbell-Burk SL, Van Aken T, Laue ED. Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy. Biochemistry. 33: 3515-31. PMID 8142349  1
1992 Campbell-Burk SL, Domaille PJ, Starovasnik MA, Boucher W, Laue ED. Sequential assignment of the backbone nuclei (1H, 15N and 13C) of c-H-ras p21 (1-166).GDP using a novel 4D NMR strategy. Journal of Biomolecular Nmr. 2: 639-46. PMID 1337001  1
1987 Campbell-Burk SL, Jones KA, Shulman RG. 31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. Biochemistry. 26: 7483-92. PMID 3322400  1
1987 Campbell-Burk SL, Shulman RG. High-resolution NMR studies of Saccharomyces cerevisiae. Annual Review of Microbiology. 41: 595-616. PMID 3318680 DOI: 10.1146/annurev.mi.41.100187.003115  1
1987 Campbell-Burk SL, den Hollander JA, Alger JR, Shulman RG. 31P NMR saturation-transfer and 13C NMR kinetic studies of glycolytic regulation during anaerobic and aerobic glycolysis. Biochemistry. 26: 7493-500. PMID 2962638  1
1985 Degani H, Laughlin M, Campbell S, Shulman RG. Kinetics of creatine kinase in heart: a 31P NMR saturation- and inversion-transfer study. Biochemistry. 24: 5510-6. PMID 4074712  1
1985 Campbell SL, Jones KA, Shulman RG. In vivo 31P nuclear magnetic resonance saturation transfer measurements of phosphate exchange reactions in the yeast Saccharomyces cerevisiae. Febs Letters. 193: 189-93. PMID 3905437  1
Show low-probability matches.