Philippa Marrack - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Biochemistry, Cell Biology

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, et al. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4. PMID 30952805 DOI: 10.1126/sciimmunol.aav7517  0.64
2018 Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, et al. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nature Communications. 9: 2650. PMID 29985393 DOI: 10.1038/s41467-018-05026-6  0.36
2018 Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Scientific Reports. 8: 3275. PMID 29459673 DOI: 10.1038/s41598-018-21432-8  0.64
2018 Antonioli AH, White J, Crawford F, Renner B, Marchbank KJ, Hannan JP, Thurman JM, Marrack P, Holers VM. Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins. Journal of Immunology (Baltimore, Md. : 1950). 200: 316-326. PMID 29187587 DOI: 10.4049/jimmunol.1602017  0.36
2017 Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255035 DOI: 10.1073/pnas.1716527115  0.64
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of the T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor. Elife. 6. PMID 29148973 DOI: 10.7554/eLife.30918  0.36
2017 Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, ... Marrack P, et al. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847961 DOI: 10.1073/pnas.1706831114  0.64
2017 Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P. The domestic cat antibody response to feline herpesvirus-1 increases with age. Veterinary Immunology and Immunopathology. 188: 65-70. PMID 28615129 DOI: 10.1016/j.vetimm.2017.05.002  0.64
2017 Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. The Journal of Clinical Investigation. PMID 28240602 DOI: 10.1172/JCI91250  0.64
2016 Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. Plos One. 11: e0166322. PMID 27880772 DOI: 10.1371/journal.pone.0166322  0.64
2016 Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine αβ T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. Journal of Immunology (Baltimore, Md. : 1950). 197: 3437-3443. PMID 27824590  0.64
2016 Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588903 DOI: 10.1073/pnas.1609717113  0.64
2016 Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. Journal of Immunology (Baltimore, Md. : 1950). PMID 27357147 DOI: 10.4049/jimmunol.1501565  0.64
2015 Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26453556 DOI: 10.1073/pnas.1517862112  0.36
2015 Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. Plos One. 10: e0136613. PMID 26317987 DOI: 10.1371/journal.pone.0136613  0.36
2015 Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. Journal of Immunology (Baltimore, Md. : 1950). 195: 71-9. PMID 26034175 DOI: 10.4049/jimmunol.1500055  0.36
2015 Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV. Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts. Journal of Immunology (Baltimore, Md. : 1950). 195: 46-50. PMID 26034174 DOI: 10.4049/jimmunol.1500669  0.36
2014 Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 158: 132-42. PMID 24995984 DOI: 10.1016/j.cell.2014.04.048  0.36
2014 Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 8553-8. PMID 24912188 DOI: 10.1073/pnas.1408048111  0.36
2014 Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the αβ T cell receptor. Journal of Molecular Medicine (Berlin, Germany). 92: 735-41. PMID 24848996 DOI: 10.1007/s00109-014-1145-2  0.36
2014 David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7735-40. PMID 24821788 DOI: 10.1073/pnas.1406218111  0.36
2014 Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proceedings of the National Academy of Sciences of the United States of America. 111: E119-28. PMID 24344267 DOI: 10.1073/pnas.1320777110  0.36
2013 Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proceedings of the National Academy of Sciences of the United States of America. 110: E3216-24. PMID 23922396 DOI: 10.1073/pnas.1312348110  0.64
2013 Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. The Journal of Experimental Medicine. 210: 1403-18. PMID 23797096 DOI: 10.1084/jem.20122426  0.36
2013 Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. Plos One. 8: e61775. PMID 23613928 DOI: 10.1371/journal.pone.0061775  0.64
2013 Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. Plos One. 8: e57435. PMID 23483882 DOI: 10.1371/journal.pone.0057435  0.36
2013 McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1122-31. PMID 23447566 DOI: 10.1073/pnas.1300392110  0.36
2013 Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. Journal of Immunology (Baltimore, Md. : 1950). 190: 1936-47. PMID 23355737 DOI: 10.4049/jimmunol.1203149  0.36
2013 Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. Plos One. 8: e53789. PMID 23342002 DOI: 10.1371/journal.pone.0053789  0.36
2013 Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein & Cell. 4: 8-16. PMID 23307779 DOI: 10.1007/s13238-012-2077-7  0.64
2013 Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. European Journal of Immunology. 43: 521-32. PMID 23172374 DOI: 10.1002/eji.201242757  0.36
2013 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunologic Research. 55: 210-6. PMID 22945807 DOI: 10.1007/s12026-012-8365-8  0.64
2012 Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proceedings of the National Academy of Sciences of the United States of America. 109: 18517-22. PMID 23091041 DOI: 10.1073/pnas.1215928109  0.36
2012 Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunological Reviews. 250: 49-60. PMID 23046122 DOI: 10.1111/imr.12004  0.64
2012 Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harbor Perspectives in Medicine. 2: a007765. PMID 22951444 DOI: 10.1101/cshperspect.a007765  0.64
2012 Bjordahl RL, Gapin L, Marrack P, Refaeli Y. iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma. Plos One. 7: e42635. PMID 22880059 DOI: 10.1371/journal.pone.0042635  0.36
2012 Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nature Immunology. 13: 705-6. PMID 22814339 DOI: 10.1038/ni.2347  0.36
2012 Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 36: 887-8. PMID 22705103 DOI: 10.1016/j.immuni.2012.05.018  0.36
2012 Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, van Dyk LF, Torres RM, Pelanda R. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 109: E1092-100. PMID 22474381 DOI: 10.1073/pnas.1203019109  0.36
2011 Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to αβ T cell receptor specificity. Immunity. 35: 526-35. PMID 21962492 DOI: 10.1016/j.immuni.2011.09.005  0.36
2011 Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proceedings of the National Academy of Sciences of the United States of America. 108: 16729-34. PMID 21949373 DOI: 10.1073/pnas.1113954108  0.36
2011 Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 35: 23-33. PMID 21683626 DOI: 10.1016/j.immuni.2011.04.017  0.36
2011 Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. Blood. 118: 1305-15. PMID 21543762 DOI: 10.1182/blood-2011-01-331462  0.64
2011 MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 7914-9. PMID 21518876 DOI: 10.1073/pnas.1104588108  0.64
2011 Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 34: 315-26. PMID 21376640 DOI: 10.1016/j.immuni.2011.01.013  0.36
2011 MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 2889-96. PMID 21270407 DOI: 10.4049/jimmunol.1002955  0.36
2010 Munks MW, McKee AS, MacLeod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P. Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo Blood. 116: 5191-5199. PMID 20876456 DOI: 10.1182/blood-2010-03-275529  0.36
2010 Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proceedings of the National Academy of Sciences of the United States of America. 107: 10978-83. PMID 20534455 DOI: 10.1073/pnas.1006545107  0.64
2010 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. Journal of Immunology (Baltimore, Md. : 1950). 184: 4592-5. PMID 20410496  0.36
2010 McKee AS, MacLeod MK, Kappler JW, Marrack P. Immune mechanisms of protection: can adjuvants rise to the challenge? Bmc Biology. 8: 37. PMID 20385031 DOI: 10.1186/1741-7007-8-37  0.64
2010 Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 7425-30. PMID 20356827 DOI: 10.1073/pnas.1001772107  0.36
2010 MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 130: 10-5. PMID 20331469 DOI: 10.1111/j.1365-2567.2010.03260.x  0.64
2010 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmunity Reviews. 9: 494-8. PMID 20144912 DOI: 10.1016/j.autrev.2010.02.008  0.64
2010 Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nature Immunology. 11: 225-31. PMID 20139986 DOI: 10.1038/ni.1844  0.36
2009 Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. Plos Biology. 7: e1000253. PMID 19956738 DOI: 10.1371/journal.pbio.1000253  0.64
2009 McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 4403-14. PMID 19734227 DOI: 10.4049/jimmunol.0900164  0.64
2009 Telerman A, Amson R, Demant P, Marrack P. Obituary: Jean Dausset. Immunity. 31: 171-3. PMID 19705522  0.36
2009 Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, et al. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31: 60-71. PMID 19592274 DOI: 10.1016/j.immuni.2009.05.010  0.36
2009 Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proceedings of the National Academy of Sciences of the United States of America. 106: 7951-6. PMID 19416894 DOI: 10.1073/pnas.0902728106  0.64
2009 Desbien AL, Kappler JW, Marrack P. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim. Proceedings of the National Academy of Sciences of the United States of America. 106: 5663-8. PMID 19293378 DOI: 10.1073/pnas.0901036106  0.64
2009 MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Seminars in Immunology. 21: 53-61. PMID 19269850 DOI: 10.1016/j.smim.2009.02.006  0.36
2009 Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 458: 1043-6. PMID 19262510 DOI: 10.1038/nature07812  0.64
2009 Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. International Immunology. 21: 339-48. PMID 19208752 DOI: 10.1093/intimm/dxp002  0.64
2008 Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nature Immunology. 9: 1356-63. PMID 18931680 DOI: 10.1038/ni.1670  0.36
2008 MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proceedings of the National Academy of Sciences of the United States of America. 105: 14521-6. PMID 18787120 DOI: 10.1073/pnas.0807449105  0.36
2008 Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proceedings of the National Academy of Sciences of the United States of America. 105: 12997-3002. PMID 18728183 DOI: 10.1073/pnas.0805465105  0.36
2008 Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proceedings of the National Academy of Sciences of the United States of America. 105: 11893-7. PMID 18697946 DOI: 10.1073/pnas.0805810105  0.64
2008 Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB. GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Research. 18: 900-10. PMID 18591963 DOI: 10.1038/cr.2008.75  0.36
2008 Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Current Opinion in Immunology. 20: 203-7. PMID 18456484 DOI: 10.1016/j.coi.2008.03.008  0.64
2008 McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. International Immunology. 20: 659-69. PMID 18343889 DOI: 10.1093/intimm/dxn025  0.64
2008 Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 28: 324-34. PMID 18308592 DOI: 10.1016/j.immuni.2008.01.008  0.64
2008 Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annual Review of Immunology. 26: 171-203. PMID 18304006 DOI: 10.1146/annurev.immunol.26.021607.090421  0.64
2008 Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Molecular Immunology. 45: 599-606. PMID 17920446 DOI: 10.1016/j.molimm.2006.03.025  0.64
2007 Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nature Immunology. 8: 1105-13. PMID 17828267 DOI: 10.1038/ni1510  0.36
2007 Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3417-24. PMID 17785775  0.64
2007 Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Current Opinion in Immunology. 19: 516-21. PMID 17644328 DOI: 10.1016/j.coi.2007.05.005  0.36
2007 Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. The Journal of Clinical Investigation. 117: 1270-81. PMID 17476359 DOI: 10.1172/JCI30513  0.36
2007 Clambey ET, Kappler JW, Marrack P. CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome. Experimental Gerontology. 42: 407-11. PMID 17197145 DOI: 10.1016/j.exger.2006.11.008  0.36
2006 Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. The Journal of Experimental Medicine. 203: 2953-61. PMID 17158961 DOI: 10.1084/jem.20061151  0.64
2006 Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 25: 929-40. PMID 17137798 DOI: 10.1016/j.immuni.2006.10.012  0.36
2006 Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nature Immunology. 7: 1191-9. PMID 17041605 DOI: 10.1038/ni1401  0.64
2006 Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proceedings of the National Academy of Sciences of the United States of America. 103: 12063-8. PMID 16880405 DOI: 10.1073/pnas.0605130103  0.64
2006 Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunological Reviews. 211: 49-57. PMID 16824116 DOI: 10.1111/j.0105-2896.2006.00383.x  0.64
2006 Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. The Journal of Experimental Medicine. 203: 1147-52. PMID 16651384 DOI: 10.1084/jem.20051736  0.36
2006 Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunological Reviews. 210: 156-70. PMID 16623770 DOI: 10.1111/j.0105-2896.2006.00365.x  0.64
2006 Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. The Journal of Experimental Medicine. 203: 731-41. PMID 16520387 DOI: 10.1084/jem.20051407  0.36
2006 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. Journal of Immunology (Baltimore, Md. : 1950). 176: 2683-90. PMID 16493022 DOI: 10.1016/0092-8674(83)90232-5  0.36
2006 Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. International Archives of Allergy and Immunology. 139: 63-74. PMID 16319493 DOI: 10.1159/000090000  0.64
2005 Boder ET, Bill JR, Nields AW, Marrack PC, Kappler JW. Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide. Biotechnology and Bioengineering. 92: 485-91. PMID 16155952 DOI: 10.1002/bit.20616  0.64
2005 Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 122: 247-60. PMID 16051149 DOI: 10.1016/j.cell.2005.05.013  0.64
2005 Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis and Rheumatism. 52: 1885-96. PMID 15934080 DOI: 10.1002/art.21098  0.36
2005 Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunological Reviews. 205: 170-89. PMID 15882353 DOI: 10.1111/j.0105-2896.2005.00265.x  0.36
2005 Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proceedings of the National Academy of Sciences of the United States of America. 102: 2476-81. PMID 15699351 DOI: 10.1073/pnas.0409798102  0.64
2004 Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P. Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7. The Journal of Experimental Medicine. 200: 1179-87. PMID 15520248 DOI: 10.1084/jem.20041129  0.36
2004 Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science (New York, N.Y.). 304: 1808-10. PMID 15205534 DOI: 10.1126/science.1089926  0.36
2004 Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7681-6. PMID 15136728 DOI: 10.1073/pnas.0402293101  0.36
2004 Huseby E, Kappler J, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? European Journal of Immunology. 34: 1243-50. PMID 15114657 DOI: 10.1002/eji.200425000  0.36
2004 Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. Plos Biology. 2: E90. PMID 15094798 DOI: 10.1371/journal.pbio.0020090  0.64
2004 Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 104: 735-43. PMID 15069016 DOI: 10.1182/blood-2003-10-3413  0.36
2004 Marrack P, Kappler J. Control of T cell viability. Annual Review of Immunology. 22: 765-87. PMID 15032596 DOI: 10.1146/annurev.immunol.22.012703.104554  0.36
2004 Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1004-9. PMID 14724296 DOI: 10.1073/pnas.0307858100  0.64
2003 Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 100: 15035-40. PMID 14657380 DOI: 10.1073/pnas.1936213100  0.36
2003 Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proceedings of the National Academy of Sciences of the United States of America. 100: 11565-70. PMID 14504410 DOI: 10.1073/pnas.1934636100  0.36
2003 Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 19: 341-52. PMID 14499110  0.64
2003 Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nature Immunology. 4: 974-81. PMID 12949532 DOI: 10.1038/ni971  0.36
2003 Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. The Journal of Clinical Investigation. 111: 575-81. PMID 12618509 DOI: 10.1172/JCI18007  0.36
2003 Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. The Journal of Experimental Medicine. 197: 567-74. PMID 12615898  0.36
2003 Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Current Opinion in Immunology. 15: 120-7. PMID 12495743  0.64
2003 Jordan MB, van Rooijen N, Izui S, Kappler J, Marrack P. Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. Blood. 101: 594-601. PMID 12393630 DOI: 10.1182/blood-2001-11-0061  0.36
2002 Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Annals of the New York Academy of Sciences. 975: 114-31. PMID 12538159  0.64
2002 Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 17: 605-15. PMID 12433367 DOI: 10.1016/S1074-7613(02)00456-9  0.36
2002 de Souza AR, Swanson B, Robertson J, Bender J, Kappler J, Marrack P. Some properties of T cells in animals. Advances in Experimental Medicine and Biology. 512: 121-8. PMID 12405195  0.36
2002 Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 16: 759-67. PMID 12121658  0.64
2002 Veng LM, Bjugstad KB, Freed CR, Marrack P, Clarkson ED, Bell KP, Hutt C, Zawada WM. Xenografts of MHC-deficient mouse embryonic mesencephalon improve behavioral recovery in hemiparkinsonian rats. Cell Transplantation. 11: 5-16. PMID 12095220  0.36
2002 Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 8832-7. PMID 12084927 DOI: 10.1073/pnas.132254399  0.36
2002 Liu X, Dai S, Crawford F, Fruge R, Marrack P, Kappler J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proceedings of the National Academy of Sciences of the United States of America. 99: 8820-5. PMID 12084926 DOI: 10.1073/pnas.132272099  0.64
2002 Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Current Opinion in Immunology. 14: 354-9. PMID 11973134  0.64
2002 Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). The Journal of Experimental Medicine. 195: 1043-52. PMID 11956295  0.64
2002 Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nature Immunology. 3: 27-32. PMID 11731800 DOI: 10.1038/ni742  0.64
2001 Marrack P, Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? Journal of Immunology (Baltimore, Md. : 1950). 167: 617-21. PMID 11441061  0.36
2001 Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nature Immunology. 2: 397-402. PMID 11323692 DOI: 10.1038/87692  0.64
2000 Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nature Immunology. 1: 107-11. PMID 11248801 DOI: 10.1038/77778  0.36
2000 Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. The Journal of Experimental Medicine. 191: 915-26. PMID 10727454  0.64
2000 Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Current Opinion in Immunology. 12: 206-9. PMID 10712937  0.36
1999 Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 12691-6. PMID 10535984  0.36
1999 Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America. 96: 9781-6. PMID 10449771  0.36
1999 Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. The Journal of Experimental Medicine. 190: 367-74. PMID 10430625  0.36
1998 Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunological Reviews. 165: 279-85. PMID 9850867  0.36
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