Philippa Marrack - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Biochemistry, Cell Biology

224 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wei P, Jordan KR, Buhrman JD, Lei J, Deng H, Marrack P, Dai S, Kappler JW, Slansky JE, Yin L. Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074778 DOI: 10.1073/pnas.2100588118  0.48
2021 Liu H, Wei P, Zhang Q, Chen Z, Aviszus K, Downing W, Peterson S, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab . Mabs. 13: 1919285. PMID 34074219 DOI: 10.1080/19420862.2021.1919285  0.68
2021 Liu H, Zhang Q, Wei P, Chen Z, Aviszus K, Yang J, Downing W, Jiang C, Liang B, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. The basis of a more contagious 501Y.V1 variant of SARS-CoV-2. Cell Research. PMID 33893398 DOI: 10.1038/s41422-021-00496-8  0.68
2021 Bai P, Zhou Q, Wei P, Bai H, Chan SK, Kappler JW, Marrack P, Yin L. Rational discovery of a cancer neoepitope harboring the KRAS G12D driver mutation. Science China. Life Sciences. PMID 33740187 DOI: 10.1007/s11427-020-1888-1  0.48
2021 Liu H, Wei P, Zhang Q, Chen Z, Aviszus K, Downing W, Peterson S, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab . Biorxiv : the Preprint Server For Biology. PMID 33619479 DOI: 10.1101/2021.02.16.431305  0.68
2021 Liu H, Zhang Q, Wei P, Chen Z, Aviszus K, Yang J, Downing W, Peterson S, Jiang C, Liang B, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, et al. The basis of a more contagious 501Y.V1 variant of SARS-COV-2. Biorxiv : the Preprint Server For Biology. PMID 33564771 DOI: 10.1101/2021.02.02.428884  0.68
2021 Bai P, Li Y, Zhou Q, Xia J, Wei PC, Deng H, Wu M, Chan SK, Kappler JW, Zhou Y, Tran E, Marrack P, Yin L. Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology. 10: 1868130. PMID 33537173 DOI: 10.1080/2162402X.2020.1868130  0.48
2021 Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine. 218. PMID 33095259 DOI: 10.1084/jem.20192135  0.48
2020 Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MK. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. PMID 32931017 DOI: 10.1111/Imm.13263  0.48
2020 Liu H, Ramachandran S, Fong N, Phang T, Lee S, Parsa P, Liu X, Harmacek L, Danhorn T, Song T, Oh S, Zhang Q, Chen Z, Zhang Q, Tu TH, ... ... Marrack P, et al. JMJD5 couples with CDK9 to release the paused RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747552 DOI: 10.1073/Pnas.2005745117  0.68
2020 Phalke S, Aviszus K, Rubtsova K, Rubtsov A, Barkes B, Powers L, Warner B, Crooks JL, Kappler JW, Fernández-Pérez ER, Maier LA, Hamzeh N, Marrack P. Age Associated B Cells Appear in Patients with Granulomatous Lung Diseases. American Journal of Respiratory and Critical Care Medicine. PMID 32501729 DOI: 10.1164/Rccm.201911-2151Oc  0.48
2020 Lee S, Liu H, Hill R, Chen C, Hong X, Crawford F, Kingsley M, Zhang Q, Liu X, Chen Z, Lengeling A, Bernt KM, Marrack P, Kappler J, Zhou Q, et al. JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife. 9. PMID 32048991 DOI: 10.7554/Elife.53930  0.68
2020 Lee S, Liu H, Hill R, Chen C, Hong X, Crawford F, Kingsley M, Zhang Q, Liu X, Chen Z, Lengeling A, Bernt KM, Marrack P, Kappler J, Zhou Q, et al. Author response: JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes Elife. DOI: 10.7554/Elife.53930.Sa2  0.68
2019 Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570608 DOI: 10.1073/Pnas.1909504116  0.48
2019 Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, et al. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4. PMID 30952805 DOI: 10.2210/Pdb6Dfq/Pdb  0.48
2018 Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, et al. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nature Communications. 9: 2650. PMID 29985393 DOI: 10.1038/S41467-018-05026-6  0.36
2018 Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Scientific Reports. 8: 3275. PMID 29459673 DOI: 10.1038/S41598-018-21432-8  0.68
2018 Antonioli AH, White J, Crawford F, Renner B, Marchbank KJ, Hannan JP, Thurman JM, Marrack P, Holers VM. Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins. Journal of Immunology (Baltimore, Md. : 1950). 200: 316-326. PMID 29187587 DOI: 10.4049/Jimmunol.1602017  0.48
2017 Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255035 DOI: 10.2210/Pdb6Blx/Pdb  0.48
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of the T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor. Elife. 6. PMID 29148973 DOI: 10.7554/Elife.30918  0.68
2017 Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, ... Marrack P, et al. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847961 DOI: 10.1073/Pnas.1706831114  0.48
2017 Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P. The domestic cat antibody response to feline herpesvirus-1 increases with age. Veterinary Immunology and Immunopathology. 188: 65-70. PMID 28615129 DOI: 10.1016/J.Vetimm.2017.05.002  0.48
2017 Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. The Journal of Clinical Investigation. PMID 28240602 DOI: 10.1172/Jci91250  0.48
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. Author response: The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor Elife. DOI: 10.7554/Elife.30918.028  0.68
2016 Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. Plos One. 11: e0166322. PMID 27880772 DOI: 10.1371/Journal.Pone.0166322  0.48
2016 Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine αβ T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. Journal of Immunology (Baltimore, Md. : 1950). 197: 3437-3443. PMID 27824590  0.48
2016 Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588903 DOI: 10.1073/Pnas.1609717113  0.48
2016 Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. Journal of Immunology (Baltimore, Md. : 1950). PMID 27357147 DOI: 10.4049/Jimmunol.1501565  0.48
2015 Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26453556 DOI: 10.1073/Pnas.1517862112  0.48
2015 Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. Plos One. 10: e0136613. PMID 26317987 DOI: 10.1371/Journal.Pone.0136613  0.48
2015 Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. Journal of Immunology (Baltimore, Md. : 1950). 195: 71-9. PMID 26034175 DOI: 10.4049/Jimmunol.1500055  0.48
2015 Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV. Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts. Journal of Immunology (Baltimore, Md. : 1950). 195: 46-50. PMID 26034174 DOI: 10.4049/Jimmunol.1500669  0.48
2014 Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 158: 132-42. PMID 24995984 DOI: 10.1016/J.Cell.2014.04.048  0.48
2014 Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 8553-8. PMID 24912188 DOI: 10.1073/Pnas.1408048111  0.48
2014 Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the αβ T cell receptor. Journal of Molecular Medicine (Berlin, Germany). 92: 735-41. PMID 24848996 DOI: 10.1007/S00109-014-1145-2  0.48
2014 David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7735-40. PMID 24821788 DOI: 10.1073/Pnas.1406218111  0.48
2014 David A, Trigunaite A, Macleod MK, Johnson AC, Marrack P, Jørgensen TN. Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice. Genes and Immunity. 15: 153-61. PMID 24477163 DOI: 10.1038/Gene.2014.2  0.48
2014 Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proceedings of the National Academy of Sciences of the United States of America. 111: E119-28. PMID 24344267 DOI: 10.1073/Pnas.1320777110  0.48
2013 Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proceedings of the National Academy of Sciences of the United States of America. 110: E3216-24. PMID 23922396 DOI: 10.1073/Pnas.1312348110  0.48
2013 Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. The Journal of Experimental Medicine. 210: 1403-18. PMID 23797096 DOI: 10.1084/Jem.20122426  0.48
2013 Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. Plos One. 8: e61775. PMID 23613928 DOI: 10.1371/Journal.Pone.0061775  0.48
2013 Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. Plos One. 8: e57435. PMID 23483882 DOI: 10.1371/Journal.Pone.0057435  0.48
2013 McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1122-31. PMID 23447566 DOI: 10.1073/Pnas.1300392110  0.48
2013 Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. Journal of Immunology (Baltimore, Md. : 1950). 190: 1936-47. PMID 23355737 DOI: 10.4049/Jimmunol.1203149  0.48
2013 Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. Plos One. 8: e53789. PMID 23342002 DOI: 10.1371/Journal.Pone.0053789  0.48
2013 Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein & Cell. 4: 8-16. PMID 23307779 DOI: 10.1007/S13238-012-2077-7  0.68
2013 Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. European Journal of Immunology. 43: 521-32. PMID 23172374 DOI: 10.1002/Eji.201242757  0.48
2013 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunologic Research. 55: 210-6. PMID 22945807 DOI: 10.1007/S12026-012-8365-8  0.48
2013 Alt F, Marrack P. Anniversary Note - Celebrating 25 years of Publication Current Opinion in Immunology. 25: iv. DOI: 10.1016/S0952-7915(13)00024-1  0.48
2012 Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proceedings of the National Academy of Sciences of the United States of America. 109: 18517-22. PMID 23091041 DOI: 10.1073/Pnas.1215928109  0.48
2012 Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunological Reviews. 250: 49-60. PMID 23046122 DOI: 10.1111/Imr.12004  0.48
2012 Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harbor Perspectives in Medicine. 2: a007765. PMID 22951444 DOI: 10.1101/Cshperspect.A007765  0.48
2012 Bjordahl RL, Gapin L, Marrack P, Refaeli Y. iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma. Plos One. 7: e42635. PMID 22880059 DOI: 10.1371/Journal.Pone.0042635  0.36
2012 Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nature Immunology. 13: 705-6. PMID 22814339 DOI: 10.1038/Ni.2347  0.68
2012 Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 36: 887-8. PMID 22705103 DOI: 10.1016/J.Immuni.2012.05.018  0.48
2012 Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, van Dyk LF, Torres RM, Pelanda R. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 109: E1092-100. PMID 22474381 DOI: 10.1073/Pnas.1203019109  0.48
2012 Bosio CM, Macleod M, Marrack P, Kedl RM. Utility of Mouse Models in Vaccine Design and Development Vaccinology: Principles and Practice. 94-109. DOI: 10.1002/9781118345313.ch7  0.48
2011 Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to αβ T cell receptor specificity. Immunity. 35: 526-35. PMID 21962492 DOI: 10.1016/J.Immuni.2011.09.005  0.48
2011 Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proceedings of the National Academy of Sciences of the United States of America. 108: 16729-34. PMID 21949373 DOI: 10.1073/Pnas.1113954108  0.48
2011 Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 35: 23-33. PMID 21683626 DOI: 10.1016/J.Immuni.2011.04.017  0.48
2011 Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. Blood. 118: 1305-15. PMID 21543762 DOI: 10.1182/Blood-2011-01-331462  0.48
2011 MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 7914-9. PMID 21518876 DOI: 10.1073/Pnas.1104588108  0.48
2011 Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 34: 315-26. PMID 21376640 DOI: 10.1016/J.Immuni.2011.01.013  0.48
2011 MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 2889-96. PMID 21270407 DOI: 10.4049/Jimmunol.1002955  0.48
2010 Munks MW, McKee AS, MacLeod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P. Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo Blood. 116: 5191-5199. PMID 20876456 DOI: 10.1182/Blood-2010-03-275529  0.48
2010 Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proceedings of the National Academy of Sciences of the United States of America. 107: 10978-83. PMID 20534455 DOI: 10.1073/Pnas.1006545107  0.48
2010 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. Journal of Immunology (Baltimore, Md. : 1950). 184: 4592-5. PMID 20410496  0.48
2010 McKee AS, MacLeod MK, Kappler JW, Marrack P. Immune mechanisms of protection: can adjuvants rise to the challenge? Bmc Biology. 8: 37. PMID 20385031 DOI: 10.1186/1741-7007-8-37  0.48
2010 Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 7425-30. PMID 20356827 DOI: 10.1073/Pnas.1001772107  0.48
2010 MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 130: 10-5. PMID 20331469 DOI: 10.1111/J.1365-2567.2010.03260.X  0.48
2010 Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmunity Reviews. 9: 494-8. PMID 20144912 DOI: 10.1016/J.Autrev.2010.02.008  0.48
2010 Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nature Immunology. 11: 225-31. PMID 20139986 DOI: 10.1038/Ni.1844  0.48
2010 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in β2M, MHC class I proteins, and CD8+ T cells Journal of Immunology. 184: 1227-1230. DOI: 10.1126/science.2112266  0.48
2009 Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. Plos Biology. 7: e1000253. PMID 19956738 DOI: 10.1371/Journal.Pbio.1000253  0.48
2009 McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 4403-14. PMID 19734227 DOI: 10.4049/Jimmunol.0900164  0.48
2009 Telerman A, Amson R, Demant P, Marrack P. Obituary: Jean Dausset. Immunity. 31: 171-3. PMID 19705522 DOI: 10.1016/J.Immuni.2009.07.004  0.48
2009 Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, et al. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31: 60-71. PMID 19592274 DOI: 10.1016/J.Immuni.2009.05.010  0.36
2009 Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proceedings of the National Academy of Sciences of the United States of America. 106: 7951-6. PMID 19416894 DOI: 10.1073/Pnas.0902728106  0.48
2009 Desbien AL, Kappler JW, Marrack P. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim. Proceedings of the National Academy of Sciences of the United States of America. 106: 5663-8. PMID 19293378 DOI: 10.1073/Pnas.0901036106  0.48
2009 MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Seminars in Immunology. 21: 53-61. PMID 19269850 DOI: 10.1016/J.Smim.2009.02.006  0.48
2009 Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 458: 1043-6. PMID 19262510 DOI: 10.1038/Nature07812  0.48
2009 Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. International Immunology. 21: 339-48. PMID 19208752 DOI: 10.1093/Intimm/Dxp002  0.48
2008 Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nature Immunology. 9: 1356-63. PMID 18931680 DOI: 10.1038/Ni.1670  0.48
2008 MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proceedings of the National Academy of Sciences of the United States of America. 105: 14521-6. PMID 18787120 DOI: 10.1073/Pnas.0807449105  0.68
2008 Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proceedings of the National Academy of Sciences of the United States of America. 105: 12997-3002. PMID 18728183 DOI: 10.1073/Pnas.0805465105  0.48
2008 Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proceedings of the National Academy of Sciences of the United States of America. 105: 11893-7. PMID 18697946 DOI: 10.1073/Pnas.0805810105  0.48
2008 Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB. GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Research. 18: 900-10. PMID 18591963 DOI: 10.1038/Cr.2008.75  0.48
2008 Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Current Opinion in Immunology. 20: 203-7. PMID 18456484 DOI: 10.1016/J.Coi.2008.03.008  0.48
2008 McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. International Immunology. 20: 659-69. PMID 18343889 DOI: 10.1093/Intimm/Dxn025  0.48
2008 Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 28: 324-34. PMID 18308592 DOI: 10.1016/J.Immuni.2008.01.008  0.48
2008 Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annual Review of Immunology. 26: 171-203. PMID 18304006 DOI: 10.1146/Annurev.Immunol.26.021607.090421  0.48
2008 Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Molecular Immunology. 45: 599-606. PMID 17920446 DOI: 10.1016/J.Molimm.2006.03.025  0.48
2007 Jørgensen TN, Roper E, Thurman JM, Marrack P, Kotzin BL. Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 × NZW)F1 mice Genes and Immunity. 8: 653-662. PMID 17882225 DOI: 10.1038/Sj.Gene.6364430  0.48
2007 Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nature Immunology. 8: 1105-13. PMID 17828267 DOI: 10.1038/Ni1510  0.68
2007 Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3417-24. PMID 17785775 DOI: 10.4049/Jimmunol.179.6.3417  0.48
2007 Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Current Opinion in Immunology. 19: 516-21. PMID 17644328 DOI: 10.1016/J.Coi.2007.05.005  0.68
2007 Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. The Journal of Clinical Investigation. 117: 1270-81. PMID 17476359 DOI: 10.1172/Jci30513  0.68
2007 Clambey ET, Kappler JW, Marrack P. CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome. Experimental Gerontology. 42: 407-11. PMID 17197145 DOI: 10.1016/J.Exger.2006.11.008  0.48
2007 Peyerl FW, Dai S, Murphy GA, Crawford F, White J, Marrack P, Kappler JW. Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex. Cell Death and Differentiation. 14: 447-52. PMID 16946732 DOI: 10.1038/Sj.Cdd.4402025  0.48
2006 Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. The Journal of Experimental Medicine. 203: 2953-61. PMID 17158961 DOI: 10.1084/Jem.20061151  0.48
2006 Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 25: 929-40. PMID 17137798 DOI: 10.1016/J.Immuni.2006.10.012  0.48
2006 Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nature Immunology. 7: 1191-9. PMID 17041605 DOI: 10.1038/Ni1401  0.48
2006 Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proceedings of the National Academy of Sciences of the United States of America. 103: 12063-8. PMID 16880405 DOI: 10.1073/pnas.0605130103  0.48
2006 Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunological Reviews. 211: 49-57. PMID 16824116 DOI: 10.1111/J.0105-2896.2006.00383.X  0.48
2006 Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. The Journal of Experimental Medicine. 203: 1147-52. PMID 16651384 DOI: 10.1084/Jem.20051736  0.48
2006 Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunological Reviews. 210: 156-70. PMID 16623770 DOI: 10.1111/J.0105-2896.2006.00365.X  0.48
2006 Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. The Journal of Experimental Medicine. 203: 731-41. PMID 16520387 DOI: 10.1084/Jem.20051407  0.48
2006 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. Journal of Immunology (Baltimore, Md. : 1950). 176: 2683-90. PMID 16493022 DOI: 10.1016/0092-8674(83)90232-5  0.48
2006 Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. International Archives of Allergy and Immunology. 139: 63-74. PMID 16319493 DOI: 10.1159/000090000  0.48
2005 Boder ET, Bill JR, Nields AW, Marrack PC, Kappler JW. Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide. Biotechnology and Bioengineering. 92: 485-91. PMID 16155952 DOI: 10.1002/Bit.20616  0.48
2005 Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 122: 247-60. PMID 16051149 DOI: 10.1016/J.Cell.2005.05.013  0.48
2005 Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis and Rheumatism. 52: 1885-96. PMID 15934080 DOI: 10.1002/Art.21098  0.48
2005 Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunological Reviews. 205: 170-89. PMID 15882353 DOI: 10.1111/J.0105-2896.2005.00265.X  0.48
2005 Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proceedings of the National Academy of Sciences of the United States of America. 102: 2476-81. PMID 15699351 DOI: 10.1073/Pnas.0409798102  0.48
2004 Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P. Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7. The Journal of Experimental Medicine. 200: 1179-87. PMID 15520248 DOI: 10.1084/Jem.20041129  0.48
2004 Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science (New York, N.Y.). 304: 1808-10. PMID 15205534 DOI: 10.1126/Science.1089926  0.68
2004 Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7681-6. PMID 15136728 DOI: 10.1073/Pnas.0402293101  0.48
2004 Huseby E, Kappler J, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? European Journal of Immunology. 34: 1243-50. PMID 15114657 DOI: 10.1002/Eji.200425000  0.68
2004 Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. Plos Biology. 2: E90. PMID 15094798 DOI: 10.1371/Journal.Pbio.0020090  0.48
2004 Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 104: 735-43. PMID 15069016 DOI: 10.1182/Blood-2003-10-3413  0.68
2004 Marrack P, Kappler J. Control of T cell viability. Annual Review of Immunology. 22: 765-87. PMID 15032596 DOI: 10.1146/Annurev.Immunol.22.012703.104554  0.68
2004 Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1004-9. PMID 14724296 DOI: 10.1073/Pnas.0307858100  0.48
2003 Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 100: 15035-40. PMID 14657380 DOI: 10.1073/Pnas.1936213100  0.68
2003 Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proceedings of the National Academy of Sciences of the United States of America. 100: 11565-70. PMID 14504410 DOI: 10.1073/Pnas.1934636100  0.68
2003 Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 19: 341-52. PMID 14499110 DOI: 10.1016/S1074-7613(03)00234-6  0.48
2003 Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nature Immunology. 4: 974-81. PMID 12949532 DOI: 10.1038/Ni971  0.48
2003 Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. The Journal of Clinical Investigation. 111: 575-81. PMID 12618509 DOI: 10.1172/Jci18007  0.68
2003 Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. The Journal of Experimental Medicine. 197: 567-74. PMID 12615898 DOI: 10.1084/Jem.20021762  0.68
2003 Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Current Opinion in Immunology. 15: 120-7. PMID 12495743 DOI: 10.1016/S0952-7915(02)00009-2  0.48
2003 Jordan MB, van Rooijen N, Izui S, Kappler J, Marrack P. Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. Blood. 101: 594-601. PMID 12393630 DOI: 10.1182/Blood-2001-11-0061  0.68
2002 Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Annals of the New York Academy of Sciences. 975: 114-31. PMID 12538159 DOI: 10.1111/J.1749-6632.2002.Tb05946.X  0.48
2002 Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 17: 605-15. PMID 12433367 DOI: 10.1016/S1074-7613(02)00456-9  0.48
2002 de Souza AR, Swanson B, Robertson J, Bender J, Kappler J, Marrack P. Some properties of T cells in animals. Advances in Experimental Medicine and Biology. 512: 121-8. PMID 12405195 DOI: 10.1007/978-1-4615-0757-4_16  0.68
2002 Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 16: 759-67. PMID 12121658 DOI: 10.1016/S1074-7613(02)00322-9  0.68
2002 Veng LM, Bjugstad KB, Freed CR, Marrack P, Clarkson ED, Bell KP, Hutt C, Zawada WM. Xenografts of MHC-deficient mouse embryonic mesencephalon improve behavioral recovery in hemiparkinsonian rats. Cell Transplantation. 11: 5-16. PMID 12095220  0.48
2002 Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 8832-7. PMID 12084927 DOI: 10.1073/Pnas.132254399  0.68
2002 Liu X, Dai S, Crawford F, Fruge R, Marrack P, Kappler J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proceedings of the National Academy of Sciences of the United States of America. 99: 8820-5. PMID 12084926 DOI: 10.1073/Pnas.132272099  0.68
2002 Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Current Opinion in Immunology. 14: 354-9. PMID 11973134 DOI: 10.1016/S0952-7915(02)00335-7  0.68
2002 Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). The Journal of Experimental Medicine. 195: 1043-52. PMID 11956295 DOI: 10.1084/Jem.20011971  0.68
2002 Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nature Immunology. 3: 27-32. PMID 11731800 DOI: 10.1038/Ni742  0.48
2001 Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cellular Immunology. 214: 110-22. PMID 12088410 DOI: 10.1006/Cimm.2001.1895  0.48
2001 Marrack P, Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? Journal of Immunology (Baltimore, Md. : 1950). 167: 617-21. PMID 11441061 DOI: 10.4049/Jimmunol.167.2.617  0.68
2001 Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nature Immunology. 2: 397-402. PMID 11323692 DOI: 10.1038/87692  0.68
2001 Ku C, Kappler J, Marrack P. The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines. Journal of Immunology. 166: 2186-2193. PMID 11160271 DOI: 10.4049/Jimmunol.166.4.2186  0.68
2000 Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nature Immunology. 1: 107-11. PMID 11248801 DOI: 10.1038/77778  0.68
2000 Meyer AL, Trollmo C, Crawford F, Marrack P, Steere AC, Huber BT, Kappler J, Hafler DA. Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers. Proceedings of the National Academy of Sciences of the United States of America. 97: 11433-8. PMID 11005833 DOI: 10.1073/Pnas.190335897  0.48
2000 White J, Kappler J, Marrack P. Production and Characterization of T-Cell Hybridomas Methods of Molecular Biology. 134: 185-193. PMID 10730258 DOI: 10.1385/1-59259-682-7:185  0.68
2000 Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. The Journal of Experimental Medicine. 191: 915-26. PMID 10727454 DOI: 10.1084/Jem.191.6.915  0.48
2000 Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Current Opinion in Immunology. 12: 206-9. PMID 10712937 DOI: 10.1016/S0952-7915(99)00075-8  0.68
2000 Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 97: 291-6. PMID 10618411 DOI: 10.1073/Pnas.97.1.291  0.68
1999 Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 12691-6. PMID 10535984 DOI: 10.1073/Pnas.96.22.12691  0.68
1999 Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America. 96: 9781-6. PMID 10449771 DOI: 10.1073/Pnas.96.17.9781  0.68
1999 Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. The Journal of Experimental Medicine. 190: 367-74. PMID 10430625 DOI: 10.1084/Jem.190.3.367  0.68
1998 Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunological Reviews. 165: 279-85. PMID 9850867 DOI: 10.1111/J.1600-065X.1998.Tb01245.X  0.48
1998 Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 9: 385-93. PMID 9768758 DOI: 10.1016/S1074-7613(00)80621-4  0.48
1998 Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 8: 675-82. PMID 9655481 DOI: 10.1016/S1074-7613(00)80572-5  0.68
1998 Liu CP, Crawford F, Marrack P, Kappler J. T cell positive selection by a high density, low affinity ligand. Proceedings of the National Academy of Sciences of the United States of America. 95: 4522-6. PMID 9539770 DOI: 10.1073/Pnas.95.8.4522  0.68
1997 Vella A, Teague TK, Ihle J, Kappler J, Marrack P. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. The Journal of Experimental Medicine. 186: 325-30. PMID 9221762 DOI: 10.1084/Jem.186.2.325  0.48
1997 Ku C, Kappler J, Marrack P. Characteristics and maintenance of CD8+ T-cell clones found in old mice Mechanisms of Ageing and Development. 94: 41-53. PMID 9147359 DOI: 10.1016/S0047-6374(96)01865-9  0.68
1997 Marrack P, Kappler J. Positive selection of thymocytes bearing αβ T cell receptors Current Opinion in Immunology. 9: 250-255. PMID 9099796 DOI: 10.1016/S0952-7915(97)80144-6  0.68
1996 Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science (New York, N.Y.). 272: 1001-4. PMID 8638119 DOI: 10.1126/Science.272.5264.1001  0.48
1996 Vella AT, Scherer MT, Schultz LD, Kappler JW, Marrack P. B cells are not essential for peripheral T-cell tolerance Proceedings of the National Academy of Sciences of the United States of America. 93: 951-955. PMID 8570666 DOI: 10.1073/Pnas.93.2.951  0.48
1995 Vella AT, McCormack JE, Linsley PS, Kappler JW, Marrack P. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity. 2: 261-70. PMID 7535182 DOI: 10.1016/1074-7613(95)90050-0  0.48
1994 Marrack P, Kappler J. Subversion of the immune system by pathogens Cell. 76: 323-332. PMID 8293466 DOI: 10.1016/0092-8674(94)90339-5  0.68
1994 Donahue JP, Ricalton NS, Behrendt CE, Rittershaus C, Calaman S, Marrack P, Kappler JW, Kotzin BL. Genetic analysis of low V beta 3 expression in humans. The Journal of Experimental Medicine. 179: 1701-6. PMID 8163947 DOI: 10.1084/Jem.179.5.1701  0.48
1994 McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 91: 2086-90. PMID 8134353 DOI: 10.1073/Pnas.91.6.2086  0.48
1994 Marrack P, Parker DC. A little of what you fancy . . Nature. 368: 397-398. PMID 8133882 DOI: 10.1038/368397A0  0.48
1994 Marrack P, Parker DC. Antagonists and partial agonists Nature. 368: 398. DOI: 10.1038/368398A0  0.48
1993 Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions Immunological Reviews. 79-92. PMID 8387458 DOI: 10.1111/J.1600-065X.1993.Tb01531.X  0.48
1993 Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II Journal of Experimental Medicine. 178: 2173-2183. PMID 8245790 DOI: 10.1084/Jem.178.6.2173  0.48
1993 Hugo P, Kappler JW, McCormack JE, Marrack P. Fibroblasts can induce thymocyte positive selection in vivo. Proceedings of the National Academy of Sciences of the United States of America. 90: 10335-9. PMID 8234295 DOI: 10.1073/Pnas.90.21.10335  0.48
1993 Scherer MT, Ignatowicz L, Winslow GM, Kappler JW, Marrack P. Superantigens: Bacterial and viral proteins that manipulate the immune system Annual Review of Cell Biology. 9: 101-128. PMID 7506550 DOI: 10.1146/Annurev.Cb.09.110193.000533  0.48
1992 Renz H, Bradley KL, Marrack P, Gelfand EW. T cells expressing variable elements of T-cell receptor β8 and β2 chain regulate murine IgE production Proceedings of the National Academy of Sciences of the United States of America. 89: 6438-6442. PMID 1385874 DOI: 10.1073/Pnas.89.14.6438  0.48
1992 Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. The Journal of Experimental Medicine. 175: 387-96. PMID 1370682 DOI: 10.1084/Jem.175.2.387  0.48
1992 Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a) Cell. 71: 719-730. PMID 1330323 DOI: 10.1016/0092-8674(92)90549-R  0.48
1992 Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. Journal of Experimental Medicine. 175: 847-852. PMID 1311018 DOI: 10.1084/Jem.175.3.847  0.48
1991 Herman A, Labrecque N, Thibodeau J, Marrack P, Kappler JW, Sekaly RP. Identification of the staphylococcal enterotoxin A superantigen binding site in the β1 domain of the human histocompatibility antigen HLA-DR Proceedings of the National Academy of Sciences of the United States of America. 88: 9954-9958. PMID 1946464 DOI: 10.1073/Pnas.88.22.9954  0.48
1991 McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cellular Immunology. 138: 413-22. PMID 1934079 DOI: 10.1016/0008-8749(91)90165-8  0.48
1991 Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P. Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor β-chain transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 88: 6682-6686. PMID 1907374 DOI: 10.1073/Pnas.88.15.6682  0.48
1991 Blackman MA, Kappler JW, Marrack P. Multiple Mechanisms of T Cell Tolerance to Mls-la Advances in Experimental Medicine and Biology. 292: 159-165. PMID 1835261 DOI: 10.1007/978-1-4684-5943-2_18  0.48
1991 Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proceedings of the National Academy of Sciences of the United States of America. 88: 8357-61. PMID 1656442 DOI: 10.1073/Pnas.88.19.8357  0.48
1990 Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells Journal of Experimental Medicine. 172: 709-717. PMID 2117633 DOI: 10.1084/Jem.172.3.709  0.48
1990 Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (New York, N.Y.). 248: 1227-30. PMID 2112266 DOI: 10.1126/Science.2112266  0.48
1990 Blackman MA, Kappler JW, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells Science. 248: 1335-1341. PMID 1972592 DOI: 10.1126/Science.1972592  0.48
1990 Marrack P, Kappler JW. The T Cell Receptors Chemical Immunology. 49: 69-81. DOI: 10.1159/000318971  0.48
1989 Blackman MA, Marrack P, Kappler J. Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science. 244: 214-217. PMID 2784868 DOI: 10.1126/Science.2784868  0.68
1989 Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 58: 1047-54. PMID 2673539 DOI: 10.1016/0092-8674(89)90503-5  0.48
1989 Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus Cold Spring Harbor Symposia On Quantitative Biology. 54: 105-110. PMID 2639749 DOI: 10.1101/Sqb.1989.054.01.013  0.48
1989 Kappler JW, Pullen A, Callahan J, Choi Y, Herman A, White J, Potts W, Wakeland E, Marrack P. Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta. Cold Spring Harbor Symposia On Quantitative Biology. 54: 401-7. PMID 2534796 DOI: 10.1101/Sqb.1989.054.01.049  0.48
1989 Kappler J, Kotzin B, Herron L, Gelfand EW, Bigler RD, Boylston A, Carrel S, Posnett DN, Choi Y, Marrack P. Vβ-specific stimulation of human T cells by staphylococcal toxins Science. 244: 811-813. PMID 2524876 DOI: 10.1126/Science.2524876  0.48
1989 White J, Herman A, Pullen AM, Kubo R, Kappler JW, Marrack P. The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell. 56: 27-35. PMID 2521300 DOI: 10.1016/0092-8674(89)90980-X  0.48
1988 Blackman MA, Kappler JW, Marrack P. T‐Cell Specificity and Repertoire Immunological Reviews. 101: 5-19. PMID 3280471 DOI: 10.1111/J.1600-065X.1988.Tb00730.X  0.48
1988 Gay D, Buus S, Pasternak J, Kappler J, Marrack P. The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia Proceedings of the National Academy of Sciences of the United States of America. 85: 5629-5633. PMID 3261012 DOI: 10.1073/Pnas.85.15.5629  0.48
1988 Marrack P, Kappler J. The T-cell repertoire for antigen and MHC Immunology Today. 9: 308-315. PMID 3076400 DOI: 10.1016/0167-5699(88)91324-2  0.68
1987 Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking Nature. 330: 179-181. PMID 3499573 DOI: 10.1038/330179A0  0.48
1987 Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus Cell. 49: 273-280. PMID 3494522 DOI: 10.1016/0092-8674(87)90568-X  0.48
1987 Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 328: 626-9. PMID 3112582 DOI: 10.1038/328626A0  0.48
1986 Marrack P, Kappler J. The T cell and its receptor. Scientific American. 254: 36-45. PMID 3484835 DOI: 10.1038/Scientificamerican0286-36  0.68
1986 Marrack P, Kappler J. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Advances in Immunology. 38: 1-30. PMID 3083653 DOI: 10.1016/S0065-2776(08)60005-X  0.68
1985 Golde WT, Kappler JW, Greenstein J, Malissen B, Hood L, Marrack P. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. The Journal of Experimental Medicine. 161: 635-40. PMID 3919144 DOI: 10.1084/Jem.161.3.635  0.32
1985 Webb SR, Li JH, MacNeil I, Marrack P, Sprent J, Wilson DB. T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes Journal of Experimental Medicine. 161: 269-274. PMID 2578545 DOI: 10.1084/Jem.161.1.269  0.48
1985 Yagüe J, White J, Coleclough C, Kappler J, Palmer E, Marrack P. The T cell receptor: the α and β chains define idiotype, and antigen and MHC specificity Cell. 42: 81-87. PMID 2410143 DOI: 10.1016/S0092-8674(85)80103-3  0.68
1984 Watts TH, Brian AA, Kappler JW, Marrack P, McConnell HM. Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proceedings of the National Academy of Sciences of the United States of America. 81: 7564-8. PMID 6334313 DOI: 10.1073/Pnas.81.23.7564  0.48
1984 Roehm N, Herron L, Cambier J, Diguisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells Cell. 38: 577-584. PMID 6331891 DOI: 10.1016/0092-8674(84)90512-9  0.48
1984 Folsom V, Gold DP, White J, Marrack P, Kappler J, Tonegawa S. Functional and inducible expression of a transfected murine class II major histocompatibility complex gene. Proceedings of the National Academy of Sciences of the United States of America. 81: 2045-9. PMID 6326101 DOI: 10.1073/Pnas.81.7.2045  0.48
1984 Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype Journal of Experimental Medicine. 160: 452-471. PMID 6206178 DOI: 10.1084/Jem.160.2.452  0.48
1984 Greenstein JL, Kappler J, Marrack P, Burakoff SJ. The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. The Journal of Experimental Medicine. 159: 1213-24. PMID 6200564 DOI: 10.1084/Jem.159.4.1213  0.68
1984 Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells Annual Review of Immunology. 2: 51-66. PMID 6085752 DOI: 10.1146/Annurev.Iy.02.040184.000411  0.68
1983 Sunshine GH, Gold DP, Wortis HH, Marrack P, Kappler JW. Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas Journal of Experimental Medicine. 158: 1745-1750. PMID 6605410 DOI: 10.1084/Jem.158.5.1745  0.48
1983 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 35: 295-302. PMID 6605199 DOI: 10.1016/0092-8674(83)90232-5  0.68
1983 Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas Cell. 34: 727-737. PMID 6605198 DOI: 10.1016/0092-8674(83)90529-9  0.48
1983 Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody Journal of Experimental Medicine. 157: 1149-1169. PMID 6601175 DOI: 10.1084/Jem.157.4.1149  0.48
1983 Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. The Journal of Experimental Medicine. 157: 600-12. PMID 6600488 DOI: 10.1084/Jem.157.2.600  0.48
1983 Marrack P, Kappler J. Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. Journal of Experimental Medicine. 157: 404-418. PMID 6401795 DOI: 10.1084/Jem.157.2.404  0.68
1983 Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunological Reviews. 76: 131-45. PMID 6363275 DOI: 10.1111/J.1600-065X.1983.Tb01100.X  0.48
1983 Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity Journal of Experimental Medicine. 158: 1635-1646. PMID 6195288 DOI: 10.1084/Jem.158.5.1635  0.48
1983 Roehm NW, Marrack P, Kappler JW. Helper signals in the plaque-forming cell response to protein-bound haptens. Journal of Experimental Medicine. 158: 317-333. PMID 6193219 DOI: 10.1084/Jem.158.2.317  0.48
1983 Kronenberg M, Kraig E, Siu G, Kapp JA, Kappler J, Marrack P, Pierce CW, Hood L. Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts Journal of Experimental Medicine. 158: 210-227. PMID 6190978 DOI: 10.1084/Jem.158.1.210  0.48
1982 Marrack P, Graham SD, Kushnir E, Leibson HJ, Roehm N, Kappler JW. Nonspecific factors in B cell responses. Immunological Reviews. 63: 33-49. PMID 7042545 DOI: 10.1111/J.1600-065X.1982.Tb00410.X  0.48
1982 Roehm NW, Marrack P, Kappler JW. Antigen-specific, H-2-restricted helper T cell hybridomas. Journal of Experimental Medicine. 156: 191-204. PMID 6177819 DOI: 10.1084/Jem.156.1.191  0.48
1978 Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages. Journal of Experimental Medicine. 147: 1596-1610. PMID 98610 DOI: 10.1084/Jem.147.6.1596  0.48
1977 Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T-cell/B-cell cooperation. VI. Distinct patterns of cross-reactivity by two human gamma-globulin-primed helper T-cell subpopulations. Cellular Immunology. 33: 20-32. PMID 71217 DOI: 10.1016/0008-8749(77)90131-9  0.48
1976 Hoffeld JT, Marrack P, Kappler JW. T-cells with different functions have different sensitivities to antigen☆☆☆ Cellular Immunology. 27: 344-345. DOI: 10.1016/0008-8749(76)90277-X  0.48
1976 Kappler JW, Marrack P. Helper T-cells recognize antigen and components of the macrophage surface membrane simultaneously Cellular Immunology. 27: 344. DOI: 10.1016/0008-8749(76)90276-8  0.48
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