Stephen W. Michnick, Ph.D. - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Abd-Rabbo D, Michnick SW. Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast. Bmc Systems Biology. 11: 38. PMID 28298210 DOI: 10.1186/S12918-017-0418-0  0.68
2016 Michnick SW, Landry CR, Levy ED, Diss G, Ear PH, Kowarzyk J, Malleshaiah MK, Messier V, Tchekanda E. Protein-Fragment Complementation Assays for Large-Scale Analysis, Functional Dissection, and Spatiotemporal Dynamic Studies of Protein-Protein Interactions in Living Cells. Cold Spring Harbor Protocols. 2016: pdb.top083543. PMID 27803260 DOI: 10.1101/Pdb.Top083543  1
2016 Malleshaiah M, Tchekanda E, Michnick SW. Real-Time Protein-Fragment Complementation Assays for Studying Temporal, Spatial, and Spatiotemporal Dynamics of Protein-Protein Interactions in Living Cells. Cold Spring Harbor Protocols. 2016: pdb.prot090068. PMID 27803255 DOI: 10.1101/Pdb.Prot090068  0.8
2016 Ear PH, Kowarzyk J, Michnick SW. Dissecting the Contingent Interactions of Protein Complexes with the Optimized Yeast Cytosine Deaminase Protein-Fragment Complementation Assay. Cold Spring Harbor Protocols. 2016: pdb.prot090043. PMID 27803254 DOI: 10.1101/Pdb.Prot090043  1
2016 Ear PH, Kowarzyk J, Booth MJ, Abd-Rabbo D, Shulist K, Hall C, Vogel J, Michnick SW. Erratum to: Combining the Optimized Yeast Cytosine Deaminase Protein Fragment Complementation Assay and an In Vitro Cdk1 Targeting Assay to Study the Regulation of the γ-Tubulin Complex. Methods in Molecular Biology (Clifton, N.J.). 1342: E1. PMID 27240595 DOI: 10.1007/978-1-4939-2957-3_22  1
2016 Sivanesan D, Beauchamp C, Quinou C, Lee J, Lesage S, Chemtob S, Rioux JD, Michnick S. IL23R variants protective against inflammatory bowel diseases (IBD) display loss of function due to impaired protein stability and intracellular trafficking. The Journal of Biological Chemistry. PMID 26887945 DOI: 10.1074/Jbc.M116.715870  1
2016 Ear PH, Kowarzyk J, Booth MJ, Abd-Rabbo D, Shulist K, Hall C, Vogel J, Michnick SW. Combining the Optimized Yeast Cytosine Deaminase Protein Fragment Complementation Assay and an In Vitro Cdk1 Targeting Assay to Study the Regulation of the γ-Tubulin Complex. Methods in Molecular Biology (Clifton, N.J.). 1342: 237-57. PMID 26254928 DOI: 10.1007/978-1-4939-2957-3_14  1
2015 Röck R, Bachmann V, Bhang HE, Malleshaiah M, Raffeiner P, Mayrhofer JE, Tschaikner PM, Bister K, Aanstad P, Pomper MG, Michnick SW, Stefan E. In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs. Scientific Reports. 5: 11133. PMID 26099953 DOI: 10.1038/Srep11133  1
2015 Remy I, Michnick SW. Mapping biochemical networks with protein fragment complementation assays. Methods in Molecular Biology (Clifton, N.J.). 1278: 467-81. PMID 25859970 DOI: 10.1007/978-1-4939-2425-7_31  1
2015 Kanshin E, Bergeron-Sandoval LP, Isik SS, Thibault P, Michnick SW. A cell-signaling network temporally resolves specific versus promiscuous phosphorylation. Cell Reports. 10: 1202-14. PMID 25704821 DOI: 10.1016/J.Celrep.2015.01.052  1
2014 Quiniou C, Domínguez-Punaro M, Cloutier F, Erfani A, Ennaciri J, Sivanesan D, Sanchez M, Chognard G, Hou X, Rivera JC, Beauchamp C, Charron G, Vilquin M, Kuchroo V, Michnick S, et al. Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R1216-30. PMID 25354400 DOI: 10.1152/Ajpregu.00540.2013  1
2014 Kelil A, Dubreuil B, Levy ED, Michnick SW. Fast and accurate discovery of degenerate linear motifs in protein sequences. Plos One. 9: e106081. PMID 25207816 DOI: 10.1371/Journal.Pone.0106081  1
2014 Levy ED, Kowarzyk J, Michnick SW. High-resolution mapping of protein concentration reveals principles of proteome architecture and adaptation. Cell Reports. 7: 1333-40. PMID 24813894 DOI: 10.1016/J.Celrep.2014.04.009  1
2014 Tchekanda E, Sivanesan D, Michnick SW. An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions. Nature Methods. 11: 641-4. PMID 24747815 DOI: 10.1038/Nmeth.2934  1
2014 Chognard G, Bellemare L, Pelletier AN, Dominguez-Punaro MC, Beauchamp C, Guyon MJ, Charron G, Morin N, Sivanesan D, Kuchroo V, Xavier R, Michnick SW, Chemtob S, Rioux JD, Lesage S. The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation. Plos One. 9: e89092. PMID 24586521 DOI: 10.1371/Journal.Pone.0089092  1
2013 Landry CR, Levy ED, Abd Rabbo D, Tarassov K, Michnick SW. Extracting insight from noisy cellular networks. Cell. 155: 983-9. PMID 24267884 DOI: 10.1016/J.Cell.2013.11.003  1
2013 Ear PH, Booth MJ, Abd-Rabbo D, Kowarzyk Moreno J, Hall C, Chen D, Vogel J, Michnick SW. Dissection of Cdk1-cyclin complexes in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 15716-21. PMID 24019491 DOI: 10.1073/Pnas.1305420110  1
2013 Messier V, Zenklusen D, Michnick SW. A nutrient-responsive pathway that determines M phase timing through control of B-cyclin mRNA stability. Cell. 153: 1080-93. PMID 23706744 DOI: 10.1016/J.Cell.2013.04.035  1
2013 Kanshin E, Michnick SW, Thibault P. Displacement of N/Q-rich peptides on TiO2 beads enhances the depth and coverage of yeast phosphoproteome analyses. Journal of Proteome Research. 12: 2905-13. PMID 23607784 DOI: 10.1021/Pr400198E  1
2012 Goyette G, Boulais J, Carruthers NJ, Landry CR, Jutras I, Duclos S, Dermine JF, Michnick SW, LaBoissière S, Lajoie G, Barreiro L, Thibault P, Desjardins M. Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution. Molecular & Cellular Proteomics : McP. 11: 1365-77. PMID 22915823 DOI: 10.1074/Mcp.M112.021048  1
2012 Levy ED, Michnick SW, Landry CR. Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2594-606. PMID 22889910 DOI: 10.1098/Rstb.2012.0078  1
2012 Vallée-Bélisle A, Michnick SW. Visualizing transient protein-folding intermediates by tryptophan-scanning mutagenesis. Nature Structural & Molecular Biology. 19: 731-6. PMID 22683996 DOI: 10.1038/Nsmb.2322  1
2012 Kanshin E, Michnick S, Thibault P. Sample preparation and analytical strategies for large-scale phosphoproteomics experiments. Seminars in Cell & Developmental Biology. 23: 843-53. PMID 22683502 DOI: 10.1016/J.Semcdb.2012.05.005  1
2011 Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nature Communications. 2: 598. PMID 22186894 DOI: 10.1038/Ncomms1605  1
2011 Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. Protein-fragment complementation assays for large-scale analysis, functional dissection and dynamic studies of protein-protein interactions in living cells. Methods in Molecular Biology (Clifton, N.J.). 756: 395-425. PMID 21870242 DOI: 10.1007/978-1-61779-160-4_25  1
2011 Freschi L, Courcelles M, Thibault P, Michnick SW, Landry CR. Phosphorylation network rewiring by gene duplication. Molecular Systems Biology. 7: 504. PMID 21734643 DOI: 10.1038/Msb.2011.43  1
2010 Boulais J, Trost M, Landry CR, Dieckmann R, Levy ED, Soldati T, Michnick SW, Thibault P, Desjardins M. Molecular characterization of the evolution of phagosomes. Molecular Systems Biology. 6: 423. PMID 20959821 DOI: 10.1038/Msb.2010.80  1
2010 Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells. Methods in Enzymology. 470: 335-68. PMID 20946817 DOI: 10.1016/S0076-6879(10)70014-8  1
2010 Levy ED, Landry CR, Michnick SW. Cell signaling. Signaling through cooperation. Science (New York, N.Y.). 328: 983-4. PMID 20489011 DOI: 10.1126/Science.1190993  1
2010 Guy J, Castonguay R, Campos-Reales Pineda NB, Jacquier V, Caron K, Michnick SW, Keillor JW. De novo helical peptides as target sequences for a specific, fluorogenic protein labelling strategy. Molecular Biosystems. 6: 976-87. PMID 20485742 DOI: 10.1039/B918205E  1
2010 Malleshaiah MK, Shahrezaei V, Swain PS, Michnick SW. The scaffold protein Ste5 directly controls a switch-like mating decision in yeast. Nature. 465: 101-5. PMID 20400943 DOI: 10.1038/Nature08946  1
2010 Lin CJ, Robert F, Sukarieh R, Michnick S, Pelletier J. The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling. Cancer Research. 70: 3199-208. PMID 20354178 DOI: 10.1158/0008-5472.Can-09-4072  1
2009 Ear PH, Michnick SW. A general life-death selection strategy for dissecting protein functions. Nature Methods. 6: 813-6. PMID 19820714 DOI: 10.1038/Nmeth.1389  1
2009 Halawani D, LeBlanc AC, Rouiller I, Michnick SW, Servant MJ, Latterich M. Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation. Molecular and Cellular Biology. 29: 4484-94. PMID 19506019 DOI: 10.1128/Mcb.00252-09  1
2009 Skoumbourdis AP, Leclair CA, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin CP, Michnick SW, Xia M, Thomas CJ. Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 3686-92. PMID 19464886 DOI: 10.1016/J.Bmcl.2009.01.057  1
2009 Landry CR, Levy ED, Michnick SW. Weak functional constraints on phosphoproteomes. Trends in Genetics : Tig. 25: 193-7. PMID 19349092 DOI: 10.1016/J.Tig.2009.03.003  1
2009 Levy ED, Landry CR, Michnick SW. How perfect can protein interactomes be? Science Signaling. 2: pe11. PMID 19261595 DOI: 10.1126/Scisignal.260Pe11  1
2008 Cheung V, Chua G, Batada NN, Landry CR, Michnick SW, Hughes TR, Winston F. Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. Plos Biology. 6: e277. PMID 18998772 DOI: 10.1371/Journal.Pbio.0060277  1
2008 Michnick SW, Sidhu SS. Submitting antibodies to binding arbitration. Nature Chemical Biology. 4: 326-9. PMID 18488004 DOI: 10.1038/Nchembio0608-326  1
2008 Tarassov K, Messier V, Landry CR, Radinovic S, Serna Molina MM, Shames I, Malitskaya Y, Vogel J, Bussey H, Michnick SW. An in vivo map of the yeast protein interactome. Science (New York, N.Y.). 320: 1465-70. PMID 18467557 DOI: 10.1126/Science.1153878  1
2008 Nyfeler B, Reiterer V, Wendeler MW, Stefan E, Zhang B, Michnick SW, Hauri HP. Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin. The Journal of Cell Biology. 180: 705-12. PMID 18283111 DOI: 10.1083/Jcb.200709100  1
2008 Manderson EN, Malleshaiah M, Michnick SW. A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF. Plos One. 3: e1500. PMID 18231587 DOI: 10.1371/Journal.Pone.0001500  1
2007 Vallée-Bélisle A, Michnick SW. Multiple tryptophan probes reveal that ubiquitin folds via a late misfolded intermediate. Journal of Molecular Biology. 374: 791-805. PMID 17949746 DOI: 10.1016/J.Jmb.2007.09.018  1
2007 Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SW. Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 16916-21. PMID 17942691 DOI: 10.1073/Pnas.0704257104  1
2007 Remy I, Ghaddar G, Michnick SW. Using the beta-lactamase protein-fragment complementation assay to probe dynamic protein-protein interactions. Nature Protocols. 2: 2302-6. PMID 17853887 DOI: 10.1038/Nprot.2007.356  1
2007 Remy I, Campbell-Valois FX, Michnick SW. Detection of protein-protein interactions using a simple survival protein-fragment complementation assay based on the enzyme dihydrofolate reductase. Nature Protocols. 2: 2120-5. PMID 17853867 DOI: 10.1038/Nprot.2007.266  1
2007 Guy J, Caron K, Dufresne S, Michnick SW, Skene WG, Keillor JW. Convergent preparation and photophysical characterization of dimaleimide dansyl fluorogens: elucidation of the maleimide fluorescence quenching mechanism. Journal of the American Chemical Society. 129: 11969-77. PMID 17850081 DOI: 10.1021/Ja0738125  1
2007 Michnick SW, Ear PH, Manderson EN, Remy I, Stefan E. Universal strategies in research and drug discovery based on protein-fragment complementation assays. Nature Reviews. Drug Discovery. 6: 569-82. PMID 17599086 DOI: 10.1038/Nrd2311  1
2007 Remy I, Michnick SW. Application of protein-fragment complementation assays in cell biology. Biotechniques. 42: 137, 139, 141 passim. PMID 17373475 DOI: 10.2144/000112396  1
2007 Campbell-Valois FX, Michnick SW. The transition state of the ras binding domain of Raf is structurally polarized based on Phi-values but is energetically diffuse. Journal of Molecular Biology. 365: 1559-77. PMID 17137592 DOI: 10.1016/J.Jmb.2006.10.079  1
2007 Campbell-Valois FX, Michnick SW. Synthesis of degenerated libraries of the ras-binding domain of raf and rapid selection of fast-folding and stable clones with the dihydrofolate reductase protein fragment complementation assay. Methods in Molecular Biology (Clifton, N.J.). 352: 249-74. PMID 17041270 DOI: 10.1385/1-59745-187-8:249  1
2006 Jacquier V, Michnick SW. Seeing is believing. Acs Chemical Biology. 1: 744-6. PMID 17240970 DOI: 10.1021/Cb600461V  1
2006 Kodadek T, Michnick S. Introduction to monitoring and manipulating signaling networks Molecular Biosystems. 2: 603-604. PMID 17216040 DOI: 10.1039/B615197N  1
2006 Michnick SW. The connectivity map. Nature Chemical Biology. 2: 663-4. PMID 17108982 DOI: 10.1038/Nchembio1206-663  1
2006 Remy I, Michnick SW. A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nature Methods. 3: 977-9. PMID 17099704 DOI: 10.1038/Nmeth979  1
2006 Michnick SW, MacDonald ML, Westwick JK. Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA). Methods (San Diego, Calif.). 40: 287-93. PMID 17071407 DOI: 10.1016/J.Ymeth.2006.07.016  1
2006 Campbell-Valois FX, Tarassov K, Michnick SW. Massive sequence perturbation of the Raf ras binding domain reveals relationships between sequence conservation, secondary structure propensity, hydrophobic core organization and stability. Journal of Molecular Biology. 362: 151-71. PMID 16916524 DOI: 10.1016/J.Jmb.2006.06.061  1
2006 Michnick SW. A luxRury of synthetic signals. Nature Biotechnology. 24: 658-60. PMID 16763594 DOI: 10.1038/Nbt0606-658  1
2006 Westwick JK, Michnick SW. Protein-fragment complementation assays (PCA) in small GTPase research and drug discovery. Methods in Enzymology. 407: 388-401. PMID 16757340 DOI: 10.1016/S0076-6879(05)07032-1  1
2006 MacDonald ML, Lamerdin J, Owens S, Keon BH, Bilter GK, Shang Z, Huang Z, Yu H, Dias J, Minami T, Michnick SW, Westwick JK. Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature Chemical Biology. 2: 329-37. PMID 16680159 DOI: 10.1038/Nchembio790  1
2006 Benton R, Sachse S, Michnick SW, Vosshall LB. Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. Plos Biology. 4: e20. PMID 16402857 DOI: 10.1371/Journal.Pbio.0040020  1
2005 Tarassov K, Michnick SW. iVici: Interrelational Visualization and Correlation Interface. Genome Biology. 6: R115. PMID 16420674 DOI: 10.1186/Gb-2005-6-13-R115  1
2005 Campbell-Valois FX, Tarassov K, Michnick SW. Massive sequence perturbation of a small protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 14988-93. PMID 16214894 DOI: 10.1073/Pnas.0500465102  1
2005 Tyers M, Brown E, Andrews DW, Bergeron JJ, Boone C, Bremner R, Bussey HA, Cross JC, Davies JE, Desjardins M, Dick JE, Dumont DJ, Durocher D, Ellison MJ, Golding GB, ... ... Michnick SW, et al. Problems with co-funding in Canada. Science (New York, N.Y.). 308: 1867. PMID 15976286 DOI: 10.1126/Science.308.5730.1867B  1
2005 Nyfeler B, Michnick SW, Hauri HP. Capturing protein interactions in the secretory pathway of living cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 6350-5. PMID 15849265 DOI: 10.1073/Pnas.0501976102  1
2005 Campbell-Valois FX, Michnick S. Chemical biology on PINs and NeeDLes Current Opinion in Chemical Biology. 9: 31-37. PMID 15701450 DOI: 10.1016/J.Cbpa.2004.12.009  1
2005 Maxwell KL, Wildes D, Zarrine-Afsar A, De Los Rios MA, Brown AG, Friel CT, Hedberg L, Horng JC, Bona D, Miller EJ, Vallée-Bélisle A, Main ER, Bemporad F, Qiu L, Teilum K, ... ... Michnick SW, et al. Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Science : a Publication of the Protein Society. 14: 602-16. PMID 15689503 DOI: 10.1110/Ps.041205405  1
2005 Girouard S, Houle MH, Grandbois A, Keillor JW, Michnick SW. Synthesis and characterization of dimaleimide fluorogens designed for specific labeling of proteins. Journal of the American Chemical Society. 127: 559-66. PMID 15643880 DOI: 10.1021/Ja045742X  1
2004 Leveson-Gower DB, Michnick SW, Ling V. Detection of TAP family dimerizations by an in vivo assay in mammalian cells. Biochemistry. 43: 14257-64. PMID 15518576 DOI: 10.1021/Bi0491245  1
2004 Vallée-Bélisle A, Turcotte JF, Michnick SW. raf RBD and ubiquitin proteins share similar folds, folding rates and mechanisms despite having unrelated amino acid sequences. Biochemistry. 43: 8447-58. PMID 15222756 DOI: 10.1021/Bi0359426  1
2004 Michnick S. An interview with Stephen Michnick, Ph.D. Associate Professor, Department of Biochemistry University of Montreal Assay and Drug Development Technologies. 2: 1-6. PMID 15090205  1
2004 Remy I, Michnick SW. Mapping biochemical networks with protein-fragment complementation assays. Methods in Molecular Biology (Clifton, N.J.). 261: 411-26. PMID 15064473 DOI: 10.1385/1-59259-762-9:411  1
2004 Remy I, Montmarquette A, Michnick SW. PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3. Nature Cell Biology. 6: 358-65. PMID 15048128 DOI: 10.1038/Ncb1113  1
2004 Remy I, Michnick SW. A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways. Methods (San Diego, Calif.). 32: 381-8. PMID 15003600 DOI: 10.1016/J.Ymeth.2003.10.011  1
2004 Michnick SW. Proteomics in living cells. Drug Discovery Today. 9: 262-7. PMID 15003244 DOI: 10.1016/S1359-6446(03)03022-8  1
2004 Remy I, Michnick SW. Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt. Molecular and Cellular Biology. 24: 1493-504. PMID 14749367 DOI: 10.1128/Mcb.24.4.1493-1504.2004  1
2003 Michnick SW. Protein fragment complementation strategies for biochemical network mapping. Current Opinion in Biotechnology. 14: 610-7. PMID 14662390 DOI: 10.1016/J.Copbio.2003.10.014  1
2003 Remy I, Michnick SW. Dynamic visualization of expressed gene networks. Journal of Cellular Physiology. 196: 419-29. PMID 12891699 DOI: 10.1002/Jcp.10328  1
2002 Michnick SW, Valois FX. Gene function: getting specific, generally speaking. Proceedings of the National Academy of Sciences of the United States of America. 99: 16513-5. PMID 12486243 DOI: 10.1073/Pnas.012697899  1
2002 Galarneau A, Primeau M, Trudeau LE, Michnick SW. Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions. Nature Biotechnology. 20: 619-22. PMID 12042868 DOI: 10.1038/Nbt0602-619  1
2002 Remy I, Galarneau A, Michnick SW. Detection and visualization of protein interactions with protein fragment complementation assays. Methods in Molecular Biology (Clifton, N.J.). 185: 447-59. PMID 11769008 DOI: 10.1385/1-59259-241-4:447  1
2001 Michnick SW. Exploring protein interactions by interaction-induced folding of proteins from complementary peptide fragments. Current Opinion in Structural Biology. 11: 472-7. PMID 11495741 DOI: 10.1016/S0959-440X(00)00235-9  1
2001 Subramaniam R, Desveaux D, Spickler C, Michnick SW, Brisson N. Direct visualization of protein interactions in plant cells. Nature Biotechnology. 19: 769-72. PMID 11479572 DOI: 10.1038/90831  1
2001 Remy I, Michnick SW. Visualization of biochemical networks in living cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 7678-83. PMID 11438723 DOI: 10.1073/Pnas.131216098  1
2000 Michnick SW. Chemical biology beyond binary codes. Chemistry & Biology. 7: R217-21. PMID 11137822 DOI: 10.1016/S1074-5521(00)00040-5  1
2000 Robert F, Gagnon M, Sans D, Michnick S, Brakier-Gingras L. Mapping of the RNA recognition site of Escherichia coli ribosomal protein S7 Rna. 6: 1649-1659. PMID 11105763 DOI: 10.1017/S1355838200001199  1
2000 Michnick SW, Remy I, Campbell-Valois FX, Vallée-Bélisle A, Pelletier JN. Detection of protein-protein interactions by protein fragment complementation strategies. Methods in Enzymology. 328: 208-30. PMID 11075347 DOI: 10.1016/S0076-6879(00)28399-7  1
2000 Arndt KM, Pelletier JN, Müller KM, Alber T, Michnick SW, Plückthun A. A heterodimeric coiled-coil peptide pair selected in vivo from a designed library-versus-library ensemble. Journal of Molecular Biology. 295: 627-39. PMID 10623552 DOI: 10.1006/Jmbi.1999.3352  1
1999 Michnick SW, Arnold FH. "Itching" for new strategies in protein engineering. Nature Biotechnology. 17: 1159-60. PMID 10585708 DOI: 10.1038/70699  1
1999 Pelletier JN, Arndt KM, Plückthun A, Michnick SW. An in vivo library-versus-library selection of optimized protein-protein interactions. Nature Biotechnology. 17: 683-90. PMID 10404162 DOI: 10.1038/10897  1
1999 Remy I, Michnick SW. Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays. Proceedings of the National Academy of Sciences of the United States of America. 96: 5394-9. PMID 10318894 DOI: 10.1073/Pnas.96.10.5394  1
1999 Remy I, Wilson IA, Michnick SW. Erythropoietin receptor activation by a ligand-induced conformation change. Science (New York, N.Y.). 283: 990-3. PMID 9974393 DOI: 10.1126/Science.283.5404.990  1
1998 MacKerell AD, Bashford D, Bellott M, Dunbrack RL, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FT, Mattos C, ... Michnick S, et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. The Journal of Physical Chemistry. B. 102: 3586-616. PMID 24889800 DOI: 10.1021/Jp973084F  1
1998 Pelletier JN, Campbell-Valois FX, Michnick SW. Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments. Proceedings of the National Academy of Sciences of the United States of America. 95: 12141-6. PMID 9770453 DOI: 10.1073/Pnas.95.21.12141  1
1998 Michnick SW, Shakhnovich E. A strategy for detecting the conservation of folding-nucleus residues in protein superfamilies. Folding & Design. 3: 239-51. PMID 9710570 DOI: 10.1016/S1359-0278(98)00035-2  1
1998 Beausoleil E, Sharma R, Michnick SW, Lubell WD. Alkyl 3-Position Substituents Retard the Isomerization of Prolyl and Hydroxyprolyl Amides in Water Journal of Organic Chemistry. 63: 6572-6578. DOI: 10.1021/Jo980673O  1
1998 Hanessian S, Luo X, Schaum R, Michnick S. Design of secondary structures in unnatural peptides: Stable helical γ- tetra-, hexa-, and octapeptides and consequences of α-substitution [27] Journal of the American Chemical Society. 120: 8569-8570. DOI: 10.1021/Ja9814671  1
1997 Pelletier JN, Michnick SW. A protein complementation assay for detection of protein-protein interactions in vivo Protein Engineering. 10: 89.  1
1995 DeWitte RS, Michnick SW, Shakhnovich EI. Exhaustive enumeration of protein conformations using experimental restraints. Protein Science : a Publication of the Protein Society. 4: 1780-91. PMID 8528076 DOI: 10.1002/Pro.5560040913  1
1993 Fischer S, Michnick S, Karplus M. A mechanism for rotamase catalysis by the FK506 binding protein (FKBP) Biochemistry. 32: 13830-13837. PMID 7505615 DOI: 10.1021/Bi00213A011  1
1991 Rosen MK, Michnick SW, Karplus M, Schreiber SL. Proton and nitrogen sequential assignments and secondary structure determination of the human FK506 and rapamycin binding protein. Biochemistry. 30: 4774-89. PMID 1709363 DOI: 10.1021/Bi00233A020  1
1991 Michnick SW, Rosen MK, Wandless TJ, Karplus M, Schreiber SL. Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. Science (New York, N.Y.). 252: 836-9. PMID 1709301 DOI: 10.1126/Science.1709301  1
1991 Rosen MK, Michnick SW, Wandless TJ, Schreiber SL. Study of receptor-ligand interactions through receptor labeling and isotope-edited NMR Journal of Organic Chemistry. 56: 6262-6264. DOI: 10.1021/Jo00022A007  1
1991 Wandless TJ, Michnick SW, Rosen MK, Karplus M, Schreiber SL. FK506 and rapamycin binding to FKBP: common elements in immunophilin-ligand complexation Journal of the American Chemical Society. 113: 2339-2341. DOI: 10.1021/Ja00006A083  0.36
1991 Wandless TJ, Michnick SW, Rosen MK, Karplus M, Schreiber SL. FK506 and Rapamycin Binding to FKBP: Common Elements in Immunophilin-Ligand Complexation Journal of the American Chemical Society. 113: 2339-2341.  1
1989 Carver JP, Michnick SW, Imberty A, Cumming DA. Oligosaccharide-protein interactions: a three-dimensional view. Ciba Foundation Symposium. 145: 6-18; discussion 18-. PMID 2791755  1
1989 Brockhausen I, Hull E, Hindsgaul O, Schachter H, Shah RN, Michnick SW, Carver JP. Control of glycoprotein synthesis. Detection and characterization of a novel branching enzyme from hen oviduct, UDP-N-acetylglucosamine:GlcNAc beta 1-6 (GlcNAc beta 1-2)Man alpha-R (GlcNAc to Man) beta-4-N-acetylglucosaminyltransferase VI. The Journal of Biological Chemistry. 264: 11211-21. PMID 2525556  1
1989 Cumming DA, Hellerqvist CG, Harris-Brandts M, Michnick SW, Carver JP, Bendiak B. Structures of asparagine-linked oligosaccharides of the glycoprotein fetuin having sialic acid linked to N-acetylglucosamine. Biochemistry. 28: 6500-12. PMID 2477057 DOI: 10.1021/Bi00441A051  1
1989 Bendiak B, Harris-Brandts M, Michnick SW, Carver JP, Cumming DA. Separation of the complex asparagine-linked oligosaccharides of the glycoprotein fetuin and elucidation of three triantennary structures having sialic acids linked only to galactose residues. Biochemistry. 28: 6491-9. PMID 2477056 DOI: 10.1021/Bi00441A050  1
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