Tsvee Lapidot - Publications

Affiliations: 
Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, Biochemistry

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lapidot T. Timing and regulation of hematopoietic stem cell colonization of the human fetal bone marrow by endothelial and CAR stromal cells during pregnancy. Blood Science (Baltimore, Md.). 5: 140. PMID 37228780 DOI: 10.1097/BS9.0000000000000154  0.488
2023 Ordonez-Moreno LA, Haddad M, Chakrabarti P, Khatib-Massalha E, Fruchtman H, Boura-Halfon S, Petrovich-Kopitman E, Lapidot T, Kollet O. Lactate-a new player in G-CSF-induced mobilization of hematopoietic stem/progenitor cells. Leukemia. PMID 37138018 DOI: 10.1038/s41375-023-01917-w  0.449
2021 Nevo N, Ordonez-Moreno LA, Gur-Cohen S, Avemaria F, Bhattacharya S, Khatib-Massalha E, Bertagna M, Haddad M, Chakrabarti P, Ruf W, Lapidot T, Kollet O. Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation. Leukemia. PMID 33654208 DOI: 10.1038/s41375-021-01194-5  0.465
2021 Kollet O, Khatib-Massalha E, Lapidot T. The doctor prescribed fat free diet for stem cell mobilization. Haematologica. PMID 33538158 DOI: 10.3324/haematol.2020.278239  0.317
2020 Lapidot T, Kollet O. Regulation of hematopoietic stem cell function by nitric oxide signaling. Blood Science (Baltimore, Md.). 2: 66-67. PMID 35402819 DOI: 10.1097/BS9.0000000000000045  0.392
2020 Golan K, Singh AK, Kollet O, Bertagna M, Althoff M, Khatib-Massalha E, Petrovich-Kopitman E, Wellendorf A, Massalha H, Levin-Zaidman S, Dadosh T, Bohan B, Gawali MV, Dasgupta B, Lapidot T, et al. Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma. Blood. PMID 32929449 DOI: 10.1182/Blood.2020005399  0.534
2020 Khatib-Massalha E, Bhattacharya S, Massalha H, Biram A, Golan K, Kollet O, Kumari A, Avemaria F, Petrovich-Kopitman E, Gur-Cohen S, Itkin T, Brandenburger I, Spiegel A, Shulman Z, Gerhart-Hines Z, ... ... Lapidot T, et al. Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling. Nature Communications. 11: 3547. PMID 32669546 DOI: 10.1038/S41467-020-17402-2  0.44
2019 Golan K, Kollet O, Markus RP, Lapidot T. Daily light and darkness onset and circadian rhythms metabolically synchronize hematopoietic stem cell differentiation and maintenance: The role of bone marrow norepinephrine, TNF and melatonin cycles. Experimental Hematology. PMID 31494174 DOI: 10.1016/J.Exphem.2019.08.008  0.562
2019 Golan K, Lapidot T. Daily light-and-darkness onset regulates mouse hematopoietic stem cells. Blood Advances. 3: 704. PMID 30808688 DOI: 10.1182/Bloodadvances.2018027722  0.627
2019 Khatib-Massalha E, Bhattacharya S, Massalha H, Golan K, Kollet O, Kumari A, Avemaria F, Itkin T, Gur-Cohen S, Avigdor A, Itzkovitz S, Offermanns S, Ariel A, Alon R, Lapidot T. Acute Inflammation Induces Lactate Release By Bone Marrow Neutrophils That Promotes Their Mobilization Via Endothelial GPR81 Signaling Blood. 134: 3582-3582. DOI: 10.1182/Blood-2019-123248  0.445
2018 Golan K, Kumari A, Kollet O, Khatib-Massalha E, Subramaniam MD, Ferreira ZS, Avemaria F, Rzeszotek S, García-García A, Xie S, Flores-Figueroa E, Gur-Cohen S, Itkin T, Ludin-Tal A, Massalha H, ... ... Lapidot T, et al. Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance. Cell Stem Cell. PMID 30174297 DOI: 10.1016/J.Stem.2018.08.002  0.566
2018 Nguyen TS, Lapidot T, Ruf W. Extravascular coagulation in hematopoietic stem and progenitor cell regulation. Blood. PMID 29866813 DOI: 10.1182/Blood-2017-12-768986  0.577
2018 Singh AK, Golan K, Althoff MJ, Petrovich-Kopitman E, Wellendorf AM, Mohmoud F, Bertagna M, Gonzalez-Nieto D, Barrio LC, Lapidot T, Cancelas JA. Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 Axis Blood. 132: 639-639. DOI: 10.1182/Blood-2018-99-118663  0.425
2018 Golan K, Bertagna M, Bhattacharya S, Babu-Vasandan A, Avemaria F, Khatib-Massalha E, Ferreira ZS, Kollet O, Avigdor A, Markus RP, Lapidot T. Nocturnal Melatonin Renews Bone and Blood Forming Stem Cells Reservoir By Metabolic Reprograming Blood. 132: 3326-3326. DOI: 10.1182/Blood-2018-99-118354  0.616
2018 Singh AK, Golan K, Althoff MJ, Petrovich-Kopitman E, Wellendorf AM, Mohmoud F, Bertagna M, Gonzalez-Nieto D, Barrio LC, Lapidot T, Cancelas JA. Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation Blood. 132: 872-872. DOI: 10.1182/Blood-2018-99-118292  0.473
2017 Avci S, Gur-Cohen S, Avemaria F, Lapidot T. Adhesion Assay for Murine Bone Marrow Hematopoietic Stem Cells. Bio-Protocol. 7: e2135. PMID 34458456 DOI: 10.21769/BioProtoc.2135  0.577
2017 Avemaria F, Gur-Cohen S, Avci S, Lapidot T. VLA-4 Affinity Assay for Murine Bone Marrow-derived Hematopoietic Stem Cells. Bio-Protocol. 7: e2134. PMID 34458455 DOI: 10.21769/BioProtoc.2134  0.561
2017 Itkin T, Kumari A, Schneider E, Gur-Cohen S, Ludwig C, Brooks R, Kollet O, Golan K, Khatib-Massalha E, Russo CM, Chisholm JD, Rouhi A, Geiger H, Hornstein E, Kerr WG, ... ... Lapidot T, et al. MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling. Leukemia. PMID 28174416 DOI: 10.1038/Leu.2017.50  0.552
2017 Avci S, Gur-Cohen S, Avemaria F, Lapidot T. Adhesion Assay for Murine Bone Marrow Hematopoietic Stem Cells Bio-Protocol. 7. DOI: 10.21769/bioprotoc.2135  0.513
2017 Avemaria F, Gur-Cohen S, Avci S, Lapidot T. VLA-4 Affinity Assay for Murine Bone Marrow-derived Hematopoietic Stem Cells Bio-Protocol. 7. DOI: 10.21769/bioprotoc.2134  0.498
2016 Kusumbe AP, Ramasamy SK, Itkin T, Mäe MA, Langen UH, Betsholtz C, Lapidot T, Adams RH. Corrigendum: Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature. PMID 27626373 DOI: 10.1038/Nature19782  0.368
2016 Ramasamy SK, Kusumbe AP, Itkin T, Gur-Cohen S, Lapidot T, Adams RH. Regulation of Hematopoiesis and Osteogenesis by Blood Vessel-Derived Signals. Annual Review of Cell and Developmental Biology. PMID 27576121 DOI: 10.1146/Annurev-Cellbio-111315-124936  0.585
2016 Gur-Cohen S, Lapidot T. Vascular Procr(+) stem cells: Finding new branches while looking for the roots. Cell Research. PMID 27481542 DOI: 10.1038/Cr.2016.91  0.493
2016 Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, ... ... Lapidot T, et al. Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27437586 DOI: 10.1038/Nature19088  0.791
2016 Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, Butler JM, ... ... Lapidot T, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27074509 DOI: 10.1038/Nature17624  0.859
2016 Kusumbe AP, Ramasamy SK, Itkin T, Mäe MA, Langen UH, Betsholtz C, Lapidot T, Adams RH. Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature. PMID 27074508 DOI: 10.1038/Nature17638  0.583
2016 Gur-Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, ... ... Lapidot T, et al. Corrigendum: PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nature Medicine. 22: 446. PMID 27050594 DOI: 10.1038/Nm0416-446B  0.735
2016 Gur-Cohen S, Kollet O, Graf C, Esmon CT, Ruf W, Lapidot T. Regulation of long-term repopulating hematopoietic stem cells by EPCR/PAR1 signaling. Annals of the New York Academy of Sciences. PMID 26928241 DOI: 10.1111/Nyas.13013  0.603
2016 Kusumbe A, Ramasamy S, Itkin T, Lapidot T, Adams R. Age-dependent changes in the bone marrow microenvironment Bone Abstracts. DOI: 10.1530/Boneabs.5.Ahp.Oc1.1  0.368
2016 Golan K, Kumari A, Khatib-Massalha E, Rzeszotek S, Gur-Cohen S, Ferreira ZS, Itkin T, Kollet O, Ratajczak MZ, Markus RP, Lapidot T. Daily Light and Darkness Signals Regulate Bone Marrow Stem Cell Development and Leukocyte Production Via Tnfα and an Interplay Between Norepinephrine and Melatonin Blood. 128: 721-721. DOI: 10.1182/Blood.V128.22.721.721  0.583
2016 Golan K, Wellendorf A, Takihara Y, Kumari A, Khatib-Massalha E, Kollet O, Cheng H, Cheng T, Althoff MJ, Gur-Cohen S, Itkin T, Fillipi M, Cancelas JA, Suda T, Lapidot T. Mitochondria Transfer from Hematopoietic Stem and Progenitor Cells to Pdgfrα+/Sca-1-/CD48dim BM Stromal Cells Via CX43 Gap Junctions and AMPK Signaling Inversely Regulate ROS Generation in Both Cell Populations Blood. 128: 5-5. DOI: 10.1182/Blood.V128.22.5.5  0.544
2016 Gur-Cohen S, Avemaria F, Kollet O, Avci S, Itkin T, Ramasamy SK, Kusumbe AP, Golan K, Khatib-Massalha E, Kumari A, Carolina MM, Lin W, Yu Q, Wu H, Zeng YA, ... ... Lapidot T, et al. EPCR Guides Hematopoietic Stem Cells Homing to the Bone Marrow Independently of Niche Clearance Blood. 128: 4538-4538. DOI: 10.1182/Blood.V128.22.4538.4538  0.612
2016 Nevo N, Gur-Cohen S, Kollet O, Avemaria F, Avci S, Itkin T, Chakrabarty S, Zuckerman T, Brenner B, Nadir Y, Zaidman I, Ben Arush M, Esmon C, Ruf W, Lapidot T. Inverse PAR1 Activity of Hematopoietic Stem Cells and BM Stromal Cells Mediates G-CSF-Induced Mobilization By Regulation of Nitric Oxide Generation Blood. 128: 3370-3370. DOI: 10.1182/Blood.V128.22.3370.3370  0.568
2015 Cohen SG, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, ... ... Lapidot T, et al. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nature Medicine. PMID 26457757 DOI: 10.1038/Nm.3960  0.799
2015 Maryanovich M, Zaltsman Y, Ruggiero A, Goldman A, Shachnai L, Zaidman SL, Porat Z, Golan K, Lapidot T, Gross A. An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate. Nature Communications. 6: 7901. PMID 26219591 DOI: 10.1016/J.Exphem.2015.06.132  0.425
2015 Itkin T, Gur Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Jung Y, Ledergor G, Milo I, Poulos MG, Fernandez MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, ... ... Lapidot T, et al. Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells Blood. 126: 664-664. DOI: 10.1182/Blood.V126.23.664.664  0.867
2015 Gur Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Golan K, Kalinkovich A, Esmon CT, Ruf W, Sagi I, Erez A, Lapidot T. EPCR/PAR1 Signaling Navigates Long-Term Repopulating Hematopoietic Stem Cell Bone Marrow Homing to Thrombomodulin-Enriched Blood Vessels Blood. 126: 33-33. DOI: 10.1182/Blood.V126.23.33.33  0.639
2015 Lapidot T. Metabolic regulation of hematopoietic stem cells by the bone marrow microenvironment Experimental Hematology. 43: S31. DOI: 10.1016/J.Exphem.2015.06.023  0.568
2014 Ludin A, Gur-Cohen S, Golan K, Kaufmann KB, Itkin T, Medaglia C, Lu XJ, Ledergor G, Kollet O, Lapidot T. Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment. Antioxidants & Redox Signaling. 21: 1605-19. PMID 24762207 DOI: 10.1089/Ars.2014.5941  0.791
2014 Lapidot T. Macrophages and Bone Marrow Stem Cell Niches: The Roles of PGE2 and Coagulation Blood. 124: SCI-8-SCI-8. DOI: 10.1182/Blood.V124.21.Sci-8.Sci-8  0.672
2014 Kumari A, Ludin A, Golan K, Kollet O, Niemeyer E, Friedlander N, Lapidot T. PGE2 Promotes BM Hematopoietic Stem Cell Retention Via Stromal Lactate Production­­­­, cAMP and CXCL12/CXCR4 Regulation Blood. 124: 771-771. DOI: 10.1182/Blood.V124.21.771.771  0.808
2013 Golan K, Kollet O, Lapidot T. Dynamic Cross Talk between S1P and CXCL12 Regulates Hematopoietic Stem Cells Migration, Development and Bone Remodeling. Pharmaceuticals (Basel, Switzerland). 6: 1145-69. PMID 24276423 DOI: 10.3390/Ph6091145  0.623
2013 Kollet O, Vagima Y, D'Uva G, Golan K, Canaani J, Itkin T, Gur-Cohen S, Kalinkovich A, Caglio G, Medaglia C, Ludin A, Lapid K, Shezen E, Neufeld-Cohen A, Varol D, ... ... Lapidot T, et al. Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors. Leukemia. 27: 2006-15. PMID 23680895 DOI: 10.1038/Leu.2013.154  0.855
2013 Itkin T, Kaufmann KB, Gur-Cohen S, Ludin A, Lapidot T. Fibroblast growth factor signaling promotes physiological bone remodeling and stem cell self-renewal. Current Opinion in Hematology. 20: 237-44. PMID 23567340 DOI: 10.1097/Moh.0B013E3283606162  0.792
2013 Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T. GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement. The Journal of Clinical Investigation. 123: 1705-17. PMID 23478410 DOI: 10.1172/Jci64149  0.862
2013 Schajnovitz A, Kalinkovich A, Lapid K, Berchanski A, Itkin T, Ludin A, Gur-Cohen S, Golan K, Saez B, Kollet O, Ahrens K, Proksch E, Lapidot A, Fridkin M, Scadden DT, ... Lapidot T, et al. Human and Murine β-Defensin-Derived Peptides Induce Rapid Mobilization Of Murine Hematopoietic Stem and Progenitor Cells Via Activation Of CXCR4 Signaling and CXCL12 Release Blood. 122: 890-890. DOI: 10.1182/Blood.V122.21.890.890  0.839
2013 Cohen SG, Itkin T, Ludin A, Chakrabarty S, Kollet O, Golan K, Kalinkovich A, Wong E, Erez A, Sagi I, Esmon CT, Ruf W, Lapidot T. EPCR Limits Nitric Oxide Levels, Mediating Human and Murine Stem Cell Adhesion and Retention In The Bone Marrow, By Conjugating PAR1 and CXCR4 Signaling Blood. 122: 795-795. DOI: 10.1182/Blood.V122.21.795.795  0.837
2013 Golan K, Ludin A, Itkin T, Cohen-Gur S, Kollet O, Lu X, Kalinkovich A, Maryanovich M, Gross A, Lapidot T. Hematopoietic Stem Cells and Their BM Stromal Microenvironment Share a Dynamic Inverse Metabolic State During Quiescence and Proliferation Via ROS Transfer Between The Two Populations Blood. 122: 587-587. DOI: 10.1182/Blood.V122.21.587.587  0.797
2013 Cohen SG, Itkin T, Kollet O, Chakrabarty S, Ludin A, Golan K, Kalinkovich A, Lu X, Crosby JR, Monia BP, Esmon CT, Ruf W, Lapidot T. Regulation Of Hematopoietic Stem Cell Trafficking By The Coagulation Pathway Blood. 122: 456-456. DOI: 10.1182/Blood.V122.21.456.456  0.825
2013 Golan K, Ludin A, Itkin T, Cohen-Gur S, Kollet O, Lu X, Kalinkovich A, Lapidot T. Blood Cell Replenishment and Bone Marrow Stem Cell Pool Renewal Are Regulated By Different Circadian Peaks Via Norepinephrine and TNFα/S1P Signaling Blood. 122: 217-217. DOI: 10.1182/Blood.V122.21.217.217  0.76
2013 Avigdor A, Medaglia C, Kalinkovich A, Itkin T, Bitan M, Nagler A, Lapidot T. Cathecholamines Differently Regulate Human AML and Normal Hematopoietic Progenitor Cell Motility Via miR126 and RGS16 Blood. 122: 1413-1413. DOI: 10.1182/Blood.V122.21.1413.1413  0.577
2013 Weisser M, Kaufmann KB, Itkin T, Chen-Wichmann L, Lapidot T, Grez M. Disturbed Endothelial Blood-Bone Marrow-Barrier In Nox4 Deficient Mice Blood. 122: 1169-1169. DOI: 10.1182/Blood.V122.21.1169.1169  0.628
2013 Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T. GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement (Journal of Clinical Investigation (2013) 123, 4, (1705-1717) DOI: 10.1172/JCI64149) Journal of Clinical Investigation. 123: 3183. DOI: 10.1172/JCI70656  0.848
2012 Valent P, Bonnet D, De Maria R, Lapidot T, Copland M, Melo JV, Chomienne C, Ishikawa F, Schuringa JJ, Stassi G, Huntly B, Herrmann H, Soulier J, Roesch A, Schuurhuis GJ, et al. Cancer stem cell definitions and terminology: the devil is in the details. Nature Reviews. Cancer. 12: 767-75. PMID 23051844 DOI: 10.1038/Nrc3368  0.452
2012 Ludin A, Itkin T, Gur-Cohen S, Mildner A, Shezen E, Golan K, Kollet O, Kalinkovich A, Porat Z, D'Uva G, Schajnovitz A, Voronov E, Brenner DA, Apte RN, Jung S, ... Lapidot T, et al. Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nature Immunology. 13: 1072-82. PMID 22983360 DOI: 10.1038/Ni.2408  0.852
2012 Gur-Cohen S, Lapid K, Lapidot T. Quantifying hematopoietic stem and progenitor cell mobilization. Methods in Molecular Biology (Clifton, N.J.). 904: 15-35. PMID 22890919 DOI: 10.1007/978-1-61779-943-3_2  0.824
2012 Zhao M, Ross JT, Itkin T, Perry JM, Venkatraman A, Haug JS, Hembree MJ, Deng CX, Lapidot T, He XC, Li L. FGF signaling facilitates postinjury recovery of mouse hematopoietic system. Blood. 120: 1831-42. PMID 22802336 DOI: 10.1182/Blood-2011-11-393991  0.523
2012 Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, ... Lapidot T, et al. FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation. Blood. 120: 1843-55. PMID 22645180 DOI: 10.1182/Blood-2011-11-394692  0.862
2012 Maryanovich M, Oberkovitz G, Niv H, Vorobiyov L, Zaltsman Y, Brenner O, Lapidot T, Jung S, Gross A. The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nature Cell Biology. 14: 535-41. PMID 22446738 DOI: 10.1038/Ncb2468  0.419
2012 Kollet O, Canaani J, Kalinkovich A, Lapidot T. Regulatory cross talks of bone cells, hematopoietic stem cells and the nervous system maintain hematopoiesis. Inflammation & Allergy Drug Targets. 11: 170-80. PMID 22280241 DOI: 10.2174/187152812800392760  0.57
2012 Golan K, Vagima Y, Ludin A, Itkin T, Cohen-Gur S, Kalinkovich A, Kollet O, Kim C, Schajnovitz A, Ovadya Y, Lapid K, Shivtiel S, Morris AJ, Ratajczak MZ, Lapidot T. S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release. Blood. 119: 2478-88. PMID 22279055 DOI: 10.1182/Blood-2011-06-358614  0.84
2012 Itkin T, Gur-Cohen S, Ludin A, Kalinkovich A, Golan K, Caglio G, Ornitz DM, Adams RH, Kollet O, Lapidot T. Endothelial Blood-Bone Marrow-Barrier Dynamically Regulates Balanced Stem and Progenitor Cell Trafficking and Maintenance Blood. 120: 507-507. DOI: 10.1182/Blood.V120.21.507.507  0.756
2012 Itkin T, Ludin A, Gur-Cohen S, Ludwig C, Brooks R, Golan K, Lapid K, Caglio G, Kerr W, Kuchenbauer F, Hornstein E, Lapidot T. Microrna-155 Promotes Hematopoietic Stem and Progenitor Cell Mobilization and Proliferation Blood. 120: 214-214. DOI: 10.1182/Blood.V120.21.214.214  0.806
2011 Shivtiel S, Lapid K, Kalchenko V, Avigdor A, Goichberg P, Kalinkovich A, Nagler A, Kollet O, Lapidot T. CD45 regulates homing and engraftment of immature normal and leukemic human cells in transplanted immunodeficient mice. Experimental Hematology. 39: 1161-1170.e1. PMID 21911094 DOI: 10.1016/J.Exphem.2011.08.012  0.81
2011 Berchanski A, Kalinkovich A, Ludin A, Lapidot T, Lapidot A. Insights into the mechanism of enhanced mobilization of hematopoietic progenitor cells and release of CXCL12 by a combination of AMD3100 and aminoglycoside-polyarginine conjugates. The Febs Journal. 278: 4150-65. PMID 21910828 DOI: 10.1111/J.1742-4658.2011.08348.X  0.751
2011 Golan K, Vagima Y, Goichberg P, Gur-Cohen S, Lapidot T. MT1-MMP and RECK: opposite and essential roles in hematopoietic stem and progenitor cell retention and migration. Journal of Molecular Medicine (Berlin, Germany). 89: 1167-74. PMID 21842347 DOI: 10.1007/S00109-011-0792-9  0.799
2011 Keren Z, Averbuch D, Shahaf G, Zisman-Rozen S, Golan K, Itkin T, Lapidot T, Mehr R, Melamed D. Chronic B cell deficiency from birth prevents age-related alterations in the B lineage. Journal of Immunology (Baltimore, Md. : 1950). 187: 2140-7. PMID 21810615 DOI: 10.4049/Jimmunol.1100999  0.419
2011 Canaani J, Kollet O, Lapidot T. Neural regulation of bone, marrow, and the microenvironment. Frontiers in Bioscience (Scholar Edition). 3: 1021-31. PMID 21622251 DOI: 10.2741/206  0.605
2011 Vagima Y, Lapid K, Kollet O, Goichberg P, Alon R, Lapidot T. Pathways implicated in stem cell migration: the SDF-1/CXCR4 axis. Methods in Molecular Biology (Clifton, N.J.). 750: 277-89. PMID 21618098 DOI: 10.1007/978-1-61779-145-1_19  0.866
2011 Staal FJ, Baum C, Cowan C, Dzierzak E, Hacein-Bey-Abina S, Karlsson S, Lapidot T, Lemischka I, Mendez-Ferrer S, Mikkers H, Moore K, Moreno E, Mummery CL, Robin C, Suda T, et al. Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications. Leukemia. 25: 1095-102. PMID 21527933 DOI: 10.1038/Leu.2011.52  0.478
2011 Orlovsky K, Kalinkovich A, Rozovskaia T, Shezen E, Itkin T, Alder H, Ozer HG, Carramusa L, Avigdor A, Volinia S, Buchberg A, Mazo A, Kollet O, Largman C, Croce CM, ... ... Lapidot T, et al. Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation. Proceedings of the National Academy of Sciences of the United States of America. 108: 7956-61. PMID 21518888 DOI: 10.1073/Pnas.1103154108  0.517
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Lapidot T, et al. Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells. Leukemia. 25: 1286-96. PMID 21494253 DOI: 10.1038/Leu.2011.62  0.851
2011 Schajnovitz A, Itkin T, D'Uva G, Kalinkovich A, Golan K, Ludin A, Cohen D, Shulman Z, Avigdor A, Nagler A, Kollet O, Seger R, Lapidot T. CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions. Nature Immunology. 12: 391-8. PMID 21441933 DOI: 10.1038/Ni.2017  0.875
2011 Itkin T, Lapidot T. SDF-1 keeps HSC quiescent at home. Blood. 117: 373-4. PMID 21233318 DOI: 10.1182/Blood-2010-09-307843  0.397
2011 Keren Z, Naor S, Nussbaum S, Golan K, Itkin T, Sasaki Y, Schmidt-Supprian M, Lapidot T, Melamed D. B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood. 117: 3104-12. PMID 21228330 DOI: 10.1182/Blood-2010-09-307983  0.388
2011 Tesio M, Golan K, Corso S, Giordano S, Schajnovitz A, Vagima Y, Shivtiel S, Kalinkovich A, Caione L, Gammaitoni L, Laurenti E, Buss EC, Shezen E, Itkin T, Kollet O, ... ... Lapidot T, et al. Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. Blood. 117: 419-28. PMID 20585044 DOI: 10.1182/Blood-2009-06-230359  0.841
2011 Gur-Cohen S, Itkin T, Ludin A, Kollet O, Golan K, Kalinkovich A, Shezen E, Lapidot T. Coagulation Factor Thrombin Regulates Hematopoietic Stem and Progenitor Cell Egress and Mobilization Via PAR-1 & CXCR4 Upregulation, SDF-1 Secretion and EPCR Shedding Blood. 118: 2341-2341. DOI: 10.1182/Blood.V118.21.2341.2341  0.825
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Lapidot T, et al. Erratum: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (Leukemia (April 2011) DOI:10.1038/leu.2011.62) Leukemia. 25. DOI: 10.1038/Leu.2011.132  0.842
2011 Lapidot T. Stem cell regulation by the brain bone blood triad Bone. 48: S52. DOI: 10.1016/j.bone.2011.03.013  0.451
2010 Lapidot T, Kollet O. The brain-bone-blood triad: traffic lights for stem-cell homing and mobilization. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2010: 1-6. PMID 21239763 DOI: 10.1182/Asheducation-2010.1.1  0.586
2010 Kollet O, Vagima Y, Golan K, Canaani J, D'Uva G, Itkin T, Kalinkovich A, Shezen E, Neufeld-Cohen A, Rashkovan D, Chen A, Lapidot T. Circadian Corticosterone Levels Regulate and Integrate Hematopoietic Stem and Progenitor Cell Function and Bone Remodeling Via Notch1 Signaling Blood. 116: 840-840. DOI: 10.1182/Blood.V116.21.840.840  0.826
2010 Golan K, Vagima Y, Ludin A, Itkin T, Kalinkovich A, Cohen-Gur S, Kollet O, Schajnovitz A, Shivtiel S, Lapidot T. The Chemotactic Lipid S1P Regulates Hematopoietic Progenitor Cell Egress and Mobilization Via Its Major Receptor S1P1 and by SDF-1 Inhibition In a p38/Akt/mTOR Dependent Manner Blood. 116: 553-553. DOI: 10.1182/Blood.V116.21.553.553  0.819
2010 Lapid K, D‘Uva G, Kalinkovich A, Ludin A, Golan K, Itkin T, Zollo M, Lapidot T. GSK3β Signaling Regulates the Motility of Hematopoietic Progenitors Via Prune. Blood. 116: 1553-1553. DOI: 10.1182/Blood.V116.21.1553.1553  0.861
2010 Lapid K, Itkin T, Buss EC, Lapidot T. Mobilization of hematopoietic stem and progenitor cells Bone Marrow Transplantation Across Major Genetic Barriers. 1-492. DOI: 10.1057/9789814271271_0018  0.813
2009 Kalinkovich A, Spiegel A, Shivtiel S, Kollet O, Jordaney N, Piacibello W, Lapidot T. Blood-forming stem cells are nervous: direct and indirect regulation of immature human CD34+ cells by the nervous system. Brain, Behavior, and Immunity. 23: 1059-65. PMID 19341792 DOI: 10.1016/J.Bbi.2009.03.008  0.547
2009 Vagima Y, Avigdor A, Goichberg P, Shivtiel S, Tesio M, Kalinkovich A, Golan K, Dar A, Kollet O, Petit I, Perl O, Rosenthal E, Resnick I, Hardan I, Gellman YN, ... ... Lapidot T, et al. MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. The Journal of Clinical Investigation. 119: 492-503. PMID 19197139 DOI: 10.1172/Jci36541  0.77
2009 Itkin T, Ludin A, Schajnovitz A, Kalinkovich A, Kollet O, Coffin DJ, Berg T, Piacibello W, Lapidot T. Expansion of Normal and Leukemic Hematopoietic Progenitor Cells by PTH Requires bFGF Activation of c-Kit and Its Downstream JAK2/STAT5 Signaling. Blood. 114: 2511-2511. DOI: 10.1182/Blood.V114.22.2511.2511  0.875
2008 Spiegel A, Kalinkovich A, Shivtiel S, Kollet O, Lapidot T. Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment. Cell Stem Cell. 3: 484-92. PMID 18983964 DOI: 10.1016/J.Stem.2008.10.006  0.566
2008 Shivtiel S, Kollet O, Lapid K, Schajnovitz A, Goichberg P, Kalinkovich A, Shezen E, Tesio M, Netzer N, Petit I, Sharir A, Lapidot T. CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules. The Journal of Experimental Medicine. 205: 2381-95. PMID 18779349 DOI: 10.1084/Jem.20080072  0.863
2008 Aicher A, Kollet O, Heeschen C, Liebner S, Urbich C, Ihling C, Orlandi A, Lapidot T, Zeiher AM, Dimmeler S. The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche. Circulation Research. 103: 796-803. PMID 18776043 DOI: 10.1161/Circresaha.107.172718  0.659
2008 Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R. A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. Journal of Leukocyte Biology. 84: 1130-40. PMID 18653785 DOI: 10.1189/Jlb.0208088  0.471
2008 Spiegel A, Zcharia E, Vagima Y, Itkin T, Kalinkovich A, Dar A, Kollet O, Netzer N, Golan K, Shafat I, Ilan N, Nagler A, Vlodavsky I, Lapidot T. Heparanase regulates retention and proliferation of primitive Sca-1+/c-Kit+/Lin- cells via modulation of the bone marrow microenvironment. Blood. 111: 4934-43. PMID 18334674 DOI: 10.1182/Blood-2007-10-116145  0.847
2008 Schajnovitz A, Itkin T, Ludin A, Kalinkovich A, Lapid K, Seger R, Lapidot T. Functional SDF-1 Secretion from BM Stromal Cells Is a Cell Contact-Dependent Event Mediated by Cx43 and Cx45 Gap-Junctions Blood. 112: 319-319. DOI: 10.1182/Blood.V112.11.319.319  0.852
2008 Buss EC, Kalinkovich A, Schajnovitz A, Kollet O, Dar A, Tesio M, Fruehauf S, Hotfilder M, Ho AD, Shultz LD, Lapidot T. In Vivo Mobilization of Leukemic Human Precursor-B-ALL Cells by the CXCR4-Antagonist AMD3100 Is Via Secretion of SDF-1 and Synergistically by Catecholamine Action. Blood. 112: 1920-1920. DOI: 10.1182/Blood.V112.11.1920.1920  0.819
2007 Lapidot T, Goichberg P, Lapid K, Avigdor A, Kollet O. The endosteum region keeps human leukemic stem cells alive. Cell Stem Cell. 1: 483-4. PMID 18938742 DOI: 10.1016/J.Stem.2007.10.013  0.81
2007 Spiegel A, Shivtiel S, Kalinkovich A, Ludin A, Netzer N, Goichberg P, Azaria Y, Resnick I, Hardan I, Ben-Hur H, Nagler A, Rubinstein M, Lapidot T. Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling. Nature Immunology. 8: 1123-31. PMID 17828268 DOI: 10.1038/Ni1509  0.765
2007 Kollet O, Dar A, Lapidot T. The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization. Annual Review of Immunology. 25: 51-69. PMID 17042735 DOI: 10.1146/Annurev.Immunol.25.022106.141631  0.581
2007 Avigdor A, Vagima Y, Goichberg P, Shivtiel S, Tesio M, Dar A, Kalinkovich A, Petit I, Perl O, Rosenthal E, Resnick I, Hardan I, Nagler A, Lapidot T. MT1-MMP and RECK Inversely Regulate Hematopoietic Progenitor Cell Egress. Blood. 110: 1259-1259. DOI: 10.1182/Blood.V110.11.1259.1259  0.774
2006 Kalinkovich A, Tavor S, Avigdor A, Kahn J, Brill A, Petit I, Goichberg P, Tesio M, Netzer N, Naparstek E, Hardan I, Nagler A, Resnick I, Tsimanis A, Lapidot T. Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells. Cancer Research. 66: 11013-20. PMID 17108140 DOI: 10.1158/0008-5472.Can-06-2006  0.51
2006 Moskovits N, Kalinkovich A, Bar J, Lapidot T, Oren M. p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Research. 66: 10671-6. PMID 17108103 DOI: 10.1158/0008-5472.Can-06-2323  0.406
2006 Kalchenko V, Shivtiel S, Malina V, Lapid K, Haramati S, Lapidot T, Brill A, Harmelin A. Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homing. Journal of Biomedical Optics. 11: 050507. PMID 17092148 DOI: 10.1117/1.2364903  0.735
2006 Gal H, Amariglio N, Trakhtenbrot L, Jacob-Hirsh J, Margalit O, Avigdor A, Nagler A, Tavor S, Ein-Dor L, Lapidot T, Domany E, Rechavi G, Givol D. Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells. Leukemia. 20: 2147-54. PMID 17039238 DOI: 10.1038/Sj.Leu.2404401  0.55
2006 Dar A, Kollet O, Lapidot T. Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice. Experimental Hematology. 34: 967-75. PMID 16863903 DOI: 10.1016/J.Exphem.2006.04.002  0.684
2006 Kollet O, Dar A, Shivtiel S, Kalinkovich A, Lapid K, Sztainberg Y, Tesio M, Samstein RM, Goichberg P, Spiegel A, Elson A, Lapidot T. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nature Medicine. 12: 657-64. PMID 16715089 DOI: 10.1038/Nm1417  0.836
2006 Pick M, Perry C, Lapidot T, Guimaraes-Sternberg C, Naparstek E, Deutsch V, Soreq H. Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. Blood. 107: 3397-406. PMID 16380450 DOI: 10.1182/Blood-2005-08-3240  0.516
2006 Goichberg P, Kalinkovich A, Borodovsky N, Tesio M, Petit I, Nagler A, Hardan I, Lapidot T. cAMP-induced PKCzeta activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors. Blood. 107: 870-9. PMID 16204315 DOI: 10.1182/Blood-2005-03-0941  0.508
2006 Cottler-Fox M, Lapidot T. Mobilizing the older patient with myeloma. Blood Reviews. 20: 43-50. PMID 16125290 DOI: 10.1016/J.Blre.2005.06.001  0.515
2006 Kalinkovich A, Tavor S, Avigdor A, Kahn J, Brill A, Petit I, Goichberg P, Tesio M, Netzer N, Naparstek E, Hardan I, Nagler A, Resnick I, Tsimanis A, Lapidot T. Functional CXCR4 Expressing Microparticles and SDF-1 Correlate with Circulating AML Cell Counts. Blood. 108: 4375-4375. DOI: 10.1182/Blood.V108.11.4375.4375  0.514
2006 Tesio M, Kalinkovich A, Schajnovitz A, Dar A, Kollet O, Goichberg P, Petit I, Giordano S, Aglietta M, Piacibello W, Lapidot T. The Tyrosine Kinase c-Met Is Selectively Expressed on Motile Hematopoietic Progenitors Following G-CSF Administration and Promotes Mobilization by Regulating Stem Cell Niche Components. Blood. 108: 3376-3376. DOI: 10.1182/Blood.V108.11.3376.3376  0.83
2006 Dar A, Kalinkovich A, Netzer N, Margalit R, Schajnovitz A, Baleux F, Tesio M, Petit I, Lapidot T. AMD3100 Signals Via the Nervous System, Inducing Release to the Circulation of Bone Marrow SDF-1, Which Is Crucial for Progenitor Cell Mobilization. Blood. 108: 1315-1315. DOI: 10.1182/Blood.V108.11.1315.1315  0.848
2005 Dick JE, Lapidot T. Biology of normal and acute myeloid leukemia stem cells. International Journal of Hematology. 82: 389-96. PMID 16533740 DOI: 10.1532/Ijh97.05144  0.58
2005 Dar A, Goichberg P, Shinder V, Kalinkovich A, Kollet O, Netzer N, Margalit R, Zsak M, Nagler A, Hardan I, Resnick I, Rot A, Lapidot T. Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nature Immunology. 6: 1038-46. PMID 16170318 DOI: 10.1038/Ni1251  0.562
2005 Zanin-Zhorov A, Tal G, Shivtiel S, Cohen M, Lapidot T, Nussbaum G, Margalit R, Cohen IR, Lider O. Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 175: 276-85. PMID 15972659 DOI: 10.4049/Jimmunol.175.1.276  0.463
2005 Tavor S, Petit I, Porozov S, Goichberg P, Avigdor A, Sagiv S, Nagler A, Naparstek E, Lapidot T. Motility, proliferation, and egress to the circulation of human AML cells are elastase dependent in NOD/SCID chimeric mice. Blood. 106: 2120-7. PMID 15941909 DOI: 10.1182/Blood-2004-12-4969  0.601
2005 Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood. 106: 1901-10. PMID 15890683 DOI: 10.1182/Blood-2005-04-1417  0.622
2005 Byk T, Kahn J, Kollet O, Petit I, Samira S, Shivtiel S, Ben-Hur H, Peled A, Piacibello W, Lapidot T. Cycling G1 CD34+/CD38+ cells potentiate the motility and engraftment of quiescent G0 CD34+/CD38-/low severe combined immunodeficiency repopulating cells. Stem Cells (Dayton, Ohio). 23: 561-74. PMID 15790777 DOI: 10.1634/Stemcells.2004-0060  0.495
2005 Zannettino AC, Farrugia AN, Kortesidis A, Manavis J, To LB, Martin SK, Diamond P, Tamamura H, Lapidot T, Fujii N, Gronthos S. Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. Cancer Research. 65: 1700-9. PMID 15753365 DOI: 10.1158/0008-5472.Can-04-1687  0.379
2005 Kortesidis A, Zannettino A, Isenmann S, Shi S, Lapidot T, Gronthos S. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood. 105: 3793-801. PMID 15677562 DOI: 10.1182/Blood-2004-11-4349  0.546
2005 Petit I, Goichberg P, Spiegel A, Peled A, Brodie C, Seger R, Nagler A, Alon R, Lapidot T. Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. The Journal of Clinical Investigation. 115: 168-76. PMID 15630457 DOI: 10.1172/JCI21773  0.557
2005 Petit I, Goichberg P, Spiegel A, Peled A, Brodie C, Seger R, Nagler A, Alon R, Lapidot T. Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34+ progenitor cells Journal of Clinical Investigation. 115: 168-176. DOI: 10.1172/Jci200521773  0.603
2004 Samira S, Ferrand C, Peled A, Nagler A, Tovbin Y, Ben-Hur H, Taylor N, Globerson A, Lapidot T. Tumor necrosis factor promotes human T-cell development in nonobese diabetic/severe combined immunodeficient mice. Stem Cells (Dayton, Ohio). 22: 1085-100. PMID 15536198 DOI: 10.1634/Stemcells.22-6-1085  0.54
2004 Monaco G, Belmont JW, Konopleva M, Andreeff M, Tavor S, Petit I, Kollet O, Lapidot T. Correlation between CXCR4 and homing or engraftment of acute myelogenous leukemia. Cancer Research. 64: 6832 author reply 68. PMID 15375005 DOI: 10.1158/0008-5472.Can-04-1936  0.543
2004 Kang TB, Ben-Moshe T, Varfolomeev EE, Pewzner-Jung Y, Yogev N, Jurewicz A, Waisman A, Brenner O, Haffner R, Gustafsson E, Ramakrishnan P, Lapidot T, Wallach D. Caspase-8 serves both apoptotic and nonapoptotic roles. Journal of Immunology (Baltimore, Md. : 1950). 173: 2976-84. PMID 15322156 DOI: 10.4049/Jimmunol.173.5.2976  0.396
2004 Tavor S, Petit I, Porozov S, Avigdor A, Dar A, Leider-Trejo L, Shemtov N, Deutsch V, Naparstek E, Nagler A, Lapidot T. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Research. 64: 2817-24. PMID 15087398 DOI: 10.1158/0008-5472.Can-03-3693  0.633
2004 Avigdor A, Goichberg P, Shivtiel S, Dar A, Peled A, Samira S, Kollet O, Hershkoviz R, Alon R, Hardan I, Ben-Hur H, Naor D, Nagler A, Lapidot T. CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. Blood. 103: 2981-9. PMID 15070674 DOI: 10.1182/Blood-2003-10-3611  0.472
2004 Kahn J, Byk T, Jansson-Sjostrand L, Petit I, Shivtiel S, Nagler A, Hardan I, Deutsch V, Gazit Z, Gazit D, Karlsson S, Lapidot T. Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation. Blood. 103: 2942-9. PMID 15070669 DOI: 10.1182/Blood-2003-07-2607  0.587
2004 Spiegel A, Kollet O, Peled A, Abel L, Nagler A, Bielorai B, Rechavi G, Vormoor J, Lapidot T. Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. Blood. 103: 2900-7. PMID 15070661 DOI: 10.1182/Blood-2003-06-1891  0.563
2004 Hecht I, Hershkoviz R, Shivtiel S, Lapidot T, Cohen IR, Lider O, Cahalon L. Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling. Journal of Leukocyte Biology. 75: 1139-46. PMID 15020655 DOI: 10.1189/Jlb.1203659  0.319
2004 Tavor S, Petit I, Porozov S, Goichberg P, Avigdor A, Sagiv S, Nagler A, Naparstek E, Lapidot T. Motility, Proliferation and Egress of Human AML Cells in Transplanted NOD/SCID Mice Are Regulated by Membrane Bound and Secreted Elastase. Blood. 104: 3379-3379. DOI: 10.1182/Blood.V104.11.3379.3379  0.612
2004 Avigdor A, Schwartz S, Goichberg P, Petit I, Hardan I, Resnick I, Slavin S, Nagler A, Lapidot T. Membrane Type 1-Matrix Metalloproteinase Is Directly Involved in G-CSF Induced Human Hematopoietic Stem and Progenitor Cell Mobilization. Blood. 104: 2675-2675. DOI: 10.1182/Blood.V104.11.2675.2675  0.533
2004 Kollet O, Samstein R, Spiegel A, Shivtiel S, Hoffmann N, Kalinkovich A, Goichberg P, Lapidot T. Osteoclasts Are Involved in Stem Cell Mobilization: Cleavage of SDF-1 by Cathepsin K. Blood. 104: 1291-1291. DOI: 10.1182/Blood.V104.11.1291.1291  0.64
2004 Shivtiel S, Petit I, Avigdor A, Goichberg P, Samira S, Kalinkovich A, Kollet O, Nagler A, Lapidot T. CD45 Phosphatase Is Involved in Motility and Development of Hematopoietic Stem and Maturing Cells by the Regulation of Cell Adhesion and Cytokine Signaling. Blood. 104: 119-119. DOI: 10.1182/Blood.V104.11.119.119  0.561
2004 Kollet O, Lapidot T. In utero transplantation: hepatic potential of human CD34+CD45+ progenitors Blood. 104: 2207-2208. DOI: 10.1182/Blood-2004-07-2894  0.41
2003 Cottler-Fox MH, Lapidot T, Petit I, Kollet O, DiPersio JF, Link D, Devine S. Stem cell mobilization. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 419-37. PMID 14633793 DOI: 10.1182/Asheducation-2003.1.419  0.589
2003 Peller S, Frenkel J, Lapidot T, Kahn J, Rahimi-Levene N, Yona R, Nissim L, Goldfinger N, Sherman DJ, Rotter V. The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts. Oncogene. 22: 4648-55. PMID 12879009 DOI: 10.1038/Sj.Onc.1206541  0.345
2003 Kollet O, Shivtiel S, Chen YQ, Suriawinata J, Thung SN, Dabeva MD, Kahn J, Spiegel A, Dar A, Samira S, Goichberg P, Kalinkovich A, Arenzana-Seisdedos F, Nagler A, Hardan I, ... ... Lapidot T, et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. The Journal of Clinical Investigation. 112: 160-9. PMID 12865405 DOI: 10.1172/Jci17902  0.524
2003 Gammaitoni L, Bruno S, Sanavio F, Gunetti M, Kollet O, Cavalloni G, Falda M, Fagioli F, Lapidot T, Aglietta M, Piacibello W. Ex vivo expansion of human adult stem cells capable of primary and secondary hemopoietic reconstitution. Experimental Hematology. 31: 261-70. PMID 12644024 DOI: 10.1016/S0301-472X(02)01077-9  0.555
2003 Dick JE, Lapidot T. Stem cells take a shortcut to the bone marrow Blood. 101: 2901-2901. DOI: 10.1182/Blood-2003-02-0392  0.595
2002 Lapidot T, Kollet O. The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2mnull mice Leukemia. 16: 1992-2003. PMID 12357350 DOI: 10.1038/Sj.Leu.2402684  0.613
2002 Kollet O, Petit I, Kahn J, Samira S, Dar A, Peled A, Deutsch V, Gunetti M, Piacibello W, Nagler A, Lapidot T. Human CD34(+)CXCR4(-) sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation. Blood. 100: 2778-86. PMID 12351385 DOI: 10.1182/Blood-2002-02-0564  0.546
2002 Lapidot T, Petit I. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Experimental Hematology. 30: 973-81. PMID 12225788 DOI: 10.1016/S0301-472X(02)00883-4  0.613
2002 Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L, Ponomaryov T, Taichman RS, Arenzana-Seisdedos F, Fujii N, Sandbank J, Zipori D, Lapidot T. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nature Immunology. 3: 687-94. PMID 12068293 DOI: 10.1038/Ni813  0.881
2002 Peled A, Hardan I, Trakhtenbrot L, Gur E, Magid M, Darash-Yahana M, Cohen N, Grabovsky V, Franitza S, Kollet O, Lider O, Alon R, Rechavi G, Lapidot T. Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1. Stem Cells (Dayton, Ohio). 20: 259-66. PMID 12004084 DOI: 10.1634/Stemcells.20-3-259  0.544
2002 Franitza S, Kollet O, Brill A, Vaday GG, Petit I, Lapidot T, Alon R, Lider O. TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules. European Journal of Immunology. 32: 193-202. PMID 11754360 DOI: 10.1002/1521-4141(200201)32:1<193::Aid-Immu193>3.0.Co;2-H  0.394
2001 Lapidot T. Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice: The role of SDF-1/CXCR4 interactions Annals of the New York Academy of Sciences. 938: 83-95. PMID 11458529 DOI: 10.1111/J.1749-6632.2001.Tb03577.X  0.646
2001 Kollet O, Spiegel A, Peled A, Petit I, Byk T, Hershkoviz R, Guetta E, Barkai G, Magier A, Lapidot T. Rapid and efficient homing of human CD34+CD38-/lowCXCR4+ stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2mnull mice Blood. 97: 3283-3291. PMID 11342460 DOI: 10.1182/Blood.V97.10.3283  0.524
2001 Böldicke T, Tesar M, Griesel C, Rohde M, Gröne HJ, Waltenberger J, Kollet O, Lapidot T, Yayon A, Weich H. Anti-VEGFR-2 scFvs for cell isolation. Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/flk-1) on the surface of primary endothelial cells and preselected CD34+ cells from cord blood Stem Cells. 19: 24-36. PMID 11209088 DOI: 10.1634/Stemcells.19-1-24  0.42
2000 Ponomaryov T, Peled A, Petit I, Taichman RS, Habler L, Sandbank J, Arenzana-Seisdedos F, Magerus A, Caruz A, Fujii N, Nagler A, Lahav M, Szyper-Kravitz M, Zipori D, Lapidot T. Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function. The Journal of Clinical Investigation. 106: 1331-9. PMID 11104786 DOI: 10.1172/Jci10329  0.861
2000 Grabovsky V, Feigelson S, Chen C, Bleijs DA, Peled A, Cinamon G, Baleux F, Arenzana-Seisdenos F, Lapidot T, Van Kooyk Y, Lobb RR, Alon R. Subsecond induction of α4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions Journal of Experimental Medicine. 192: 495-505. PMID 10952719 DOI: 10.1084/Jem.192.4.495  0.349
2000 Kollet O, Moore JG, Aviram R, Ben-Hur H, Liu BL, Nagler A, Shultz L, Feldman M, Lapidot T. The plant lectin FRIL supports prolonged in vitro maintenance of quiescent human cord blood CD34+CD38(-/low)/SCID repopulating stem cells Experimental Hematology. 28: 726-736. PMID 10880759 DOI: 10.1016/S0301-472X(00)00163-6  0.536
2000 Peled A, Kollet O, Ponomaryov T, Petit I, Franitza S, Grabovsky V, Slav MM, Nagler A, Lider O, Alon R, Zipori D, Lapidot T. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood. 95: 3289-96. PMID 10828007 DOI: 10.1182/Blood.V95.11.3289.011K33_3289_3296  0.854
2000 Kollet O, Peled A, Byk T, Ben-Hur H, Greiner D, Shultz L, Lapidot T. β2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function Blood. 95: 3102-3105. PMID 10807775 DOI: 10.1182/Blood.V95.10.3102.010K14_3102_3105  0.581
2000 Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton RA, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1(null) mice: An immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells Journal of Immunology. 164: 2496-2507. PMID 10679087 DOI: 10.4049/Jimmunol.164.5.2496  0.445
2000 Rollet O, Grabovsky V, Franitza S, Lider O, Alon R, Lapidot T. SDF-1 induces survival, adhesion, and migration in 3D ECM like gels of murine cxcr4null fetal liver cells via another GPCR Blood. 96.  0.539
1999 Peled A, Grabovsky V, Habler L, Sandbank J, Arenzana-Seisdedos F, Petit I, Ben-Hur H, Lapidot T, Alon R. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow Journal of Clinical Investigation. 104: 1199-1211. PMID 10545519 DOI: 10.1172/Jci7615  0.452
1999 Kollet O, Aviram R, Chebath J, Ben-Hur H, Nagler A, Shultz L, Revel M, Lapidot T. The soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro maintenance and proliferation of human CD34+CD38(-/low) cells capable of repopulating severe combined immunodeficiency mice Blood. 94: 923-931. PMID 10419883 DOI: 10.1182/Blood.V94.3.923.415K08_923_931  0.469
1999 Piacibello W, Sanavio F, Severino A, Danè A, Gammaitoni L, Fagioli F, Perissinotto E, Cavalloni G, Kollet O, Lapidot T, Aglietta M. Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34+ cord blood cells after ex vivo expansion: Evidence for the amplification and self-renewal of repopulating stem cells Blood. 93: 3736-3749. PMID 10339480 DOI: 10.1182/Blood.V93.11.3736.411K01_3736_3749  0.559
1999 Globerson A, Kollet O, Abel L, Fajerman I, Ballin A, Nagler A, Slavin S, Hur HB, Hagay Z, Sharp A, Lapidot T. Differential effects of CD4+ and CD8+ cells on lymphocyte development from human cord blood cells in murine fetal thymus explants. Experimental Hematology. 27: 282-92. PMID 10029168 DOI: 10.1016/S0301-472X(98)00042-3  0.384
1999 Peled A, Petit I, Kollet O, Magid M, Ponomaryov T, Byk T, Nagler A, Ben-Hur H, Many A, Shultz L, Lider O, Alon R, Zipori D, Lapidot T. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science (New York, N.Y.). 283: 845-8. PMID 9933168 DOI: 10.1126/Science.283.5403.845  0.879
1998 Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9: 267-76. PMID 9729047 DOI: 10.1016/S1074-7613(00)80609-3  0.333
1998 Wang JCY, Lapidot T, Cashman JD, Doedens M, Addy L, Sutherland DR, Nayar R, Laraya P, Minden M, Keating A, Eaves AC, Eaves CJ, Dick JE. High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase Blood. 91: 2406-2414. PMID 9516140 DOI: 10.1182/Blood.V91.7.2406.2406_2406_2414  0.525
1997 Ariel A, Hershkoviz R, Cahalon L, Williams DE, Akiyama SK, Yamada KM, Chen C, Alon R, Lapidot T, Lider O. Induction of T cell adhesion to extracellular matrix or endothelial cell ligands by soluble or matrix-bound interleukin-7 European Journal of Immunology. 27: 2562-2570. PMID 9368611 DOI: 10.1002/Eji.1830271015  0.368
1997 Lapidot T, Fajerman Y, Kollet O. Immune-deficient SCID and NOD/SCID mice models as functional assays for studying normal and malignant human hematopoiesis Journal of Molecular Medicine. 75: 664-673. PMID 9351705 DOI: 10.1007/S001090050150  0.578
1997 Cashman JD, Lapidot T, Wang JC, Doedens M, Shultz LD, Lansdorp P, Dick JE, Eaves CJ. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood. 89: 4307-16. PMID 9192753 DOI: 10.1182/Blood.V89.12.4307  0.557
1996 Larochelle A, Vormoor J, Hanenberg H, Wang JCY, Bhatia M, Lapidot T, Moritz T, Murdoch B, Xiao XL, Kato I, Williams DA, Dick JE. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy Nature Medicine. 2: 1329-1337. PMID 8946831 DOI: 10.1038/Nm1296-1329  0.528
1996 Lapidot T, Grunberger T, Vormoor J, Estrov Z, Kollet O, Bunin N, Zaizov R, Williams DE, Freedman MH. Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice Blood. 88: 2655-2664. PMID 8839860 DOI: 10.1182/Blood.V88.7.2655.Bloodjournal8872655  0.57
1996 Sirard C, Lapidot T, Vormoor J, Cashman JD, Doedens M, Murdoch B, Jamal N, Messner H, Addey L, Minden M, Laraya P, Keating A, Eaves A, Lansdorp PM, Eaves CJ, et al. Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis Blood. 87: 1539-1548. PMID 8608245  0.448
1995 Larochelle A, Vormoor J, Lapidot T, Sher G, Furukawa T, Li Q, Shultz LD, Olivieri NF, Stamatoyannopoulos G, Dick JE. Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols. Human Molecular Genetics. 4: 163-72. PMID 7757063 DOI: 10.1093/Hmg/4.2.163  0.568
1994 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer HE, Dick JE. SCID mice as an in vivo model of human cord blood hematopoiesis Blood Cells. 20: 316-322. PMID 7538337  0.454
1994 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer HE, Dick JE. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice Blood. 83: 2489-2497. PMID 7513200  0.45
1994 Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature. 367: 645-648. PMID 7509044 DOI: 10.1038/367645A0  0.6
1994 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer H, Dick J. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice Blood. 83: 2489-2497. DOI: 10.1182/Blood.V83.9.2489.Bloodjournal8392489  0.54
1993 Pflumio F, Lapidot T, Murdoch B, Patterson B, Dick JE. Engraftment of human lymphoid cells into newborn SCID mice leads to graft-versushost disease International Immunology. 5: 1509-1522. PMID 8312221 DOI: 10.1093/Intimm/5.12.1509  0.494
1993 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer HE, Dick JE. High-level multilineage engraftment of human cord blood cells in SCID mice Journal of Hematotherapy. 2: 215-216. PMID 7921977 DOI: 10.1089/Scd.1.1993.2.215  0.443
1992 Dick JE, Sirard C, Pflumio F, Lapidot T. Murine models of normal and neoplastic human haematopoiesis Cancer Surveys. 15: 161-182. PMID 1451110  0.319
1992 Lapidot T, Faktorowich Y, Lubin I, Reisner Y. Enhancement of T-cell-depleted bone marrow allografts in the absence of graft-versus-host disease is mediated by CD8+ CD4- and not by CD8- CD4+ thymocytes Blood. 80: 2406-2411. PMID 1421412 DOI: 10.1182/Blood.V80.9.2406.2406  0.443
1992 Lapidot T, Pflumio F, Doedens M, Murdoch B, Williams DE, Dick JE. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice Science. 255: 1137-1141. PMID 1372131 DOI: 10.1126/Science.1372131  0.548
1991 Kamel-Reid S, Letarte M, Doedens M, Greaves A, Murdoch B, Grunberger T, Lapidot T, Thorner P, Freedman MH, Phillips RA, Dick JE. Bone marrow from children in relapse with pre-B acute lymphoblastic leukemia proliferates and disseminates rapidly in scid mice Blood. 78: 2973-2981. PMID 1835412 DOI: 10.1182/Blood.V78.11.2973.Bloodjournal78112973  0.502
1991 Lubin I, Faktorowich Y, Lapidot T, Gan Y, Eshhar Z, Gazit E, Levite M, Reisner Y. Engraftment and development of human T and B cells in mice after bone marrow transplantation Science. 252: 427-431. PMID 1826797 DOI: 10.1126/Science.1826797  0.462
1991 Dick JE, Lapidot T, Pflumio F. Transplantation of normal and leukemic human bone marrow into immune-deficient mice: Development of animal models for human hematopoiesis Immunological Reviews. 25-43. PMID 1804779 DOI: 10.1111/J.1600-065X.1991.Tb00614.X  0.524
1991 Dick JE, Pflumio F, Lapidot T. Mouse models for human hematopoiesis Seminars in Immunology. 3: 367-378. PMID 1799667  0.419
1990 Lapidot T, Lubin I, Terenzi A, Faktorowich Y, Erlich P, Reisner Y. Enhancement of bone marrow allografts from nude mice into mismatched recipients by T cells void of graft-versus-host activity Proceedings of the National Academy of Sciences of the United States of America. 87: 4595-4599. PMID 2191295 DOI: 10.1073/Pnas.87.12.4595  0.516
1990 Terenzi A, Lubin I, Lapidot T, Salomon O, Faktorowich Y, Rabi I, Martelli MF, Reisner Y. Enhancement of T cell-depleted bone marrow allografts in mice by thiotepa Transplantation. 50: 717-720. PMID 2120811  0.367
1989 Lapidot T, Terenzi A, Singer TS, Salomon O, Reisner Y. Enhancement by dimethyl myleran of donor type chimerism in murine recipients of bone marrow allografts. Blood. 73: 2025-32. PMID 2653469 DOI: 10.1182/Blood.V73.7.2025.2025  0.53
1988 Lapidot T, Singer TS, Salomon O, Terenzi A, Schwartz E, Reisner Y. Booster irradiation to the spleen following total body irradiation. A new immunosuppressive approach for allogeneic bone marrow transplantation. Journal of Immunology (Baltimore, Md. : 1950). 141: 2619-24. PMID 3049814  0.346
1988 Lapidot T, Singer TS, Reisner Y. Transient engraftment of T cell-depleted allogeneic bone marrow in mice improves survival rate following lethal irradiation. Bone Marrow Transplantation. 3: 157-64. PMID 3048480  0.403
1987 Schwartz E, Lapidot T, Gozes D, Singer TS, Reisner Y. Abrogation of bone marrow allograft resistance in mice by increased total body irradiation correlates with eradication of host clonable T cells and alloreactive cytotoxic precursors. Journal of Immunology (Baltimore, Md. : 1950). 138: 460-5. PMID 3098843  0.401
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