☰

Hestia S. Mellert, Ph.D. - Publications

Affiliations: 
2011 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
Tree Info Grants Similar researchers PubMed Report error

17/34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, et al. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer. Oncotarget. PMID 27590350 DOI: 10.18632/Oncotarget.11718  0.626
2016 Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction. Molecular Oncology. PMID 27341992 DOI: 10.1016/J.Molonc.2016.05.007  0.718
2014 Thangavel C, Boopathi E, Ciment S, Liu Y, O' Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5468-82. PMID 25165096 DOI: 10.1158/1078-0432.Ccr-14-0326  0.303
2014 Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Elife. 3: e02200. PMID 24867637 DOI: 10.7554/Elife.02200  0.402
2013 Mellert H, Espinosa JM. Tumor suppression by p53: is apoptosis important or not? Cell Reports. 3: 1335-6. PMID 23726020 DOI: 10.1016/j.celrep.2013.05.011  0.323
2012 Den RB, Ciment S, Sharma A, Mellert H, McMahon S, Dicker A, Knudsen KE. Differential response of prostate cancer cells to ionizing radiation: The RB status. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 106. PMID 27968000 DOI: 10.1200/Jco.2012.30.5_Suppl.106  0.59
2012 Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/Emboj.2011.382  0.608
2011 Den RB, Ciment S, Sharma A, Mellert H, Mc-Mahon S, Dicker A, Knudsen KE. Relationship between the loss of the retinoblastoma tumor suppressor and radiosensitivity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 34. PMID 27968373 DOI: 10.1200/Jco.2011.29.7_Suppl.34  0.319
2011 Zhang XY, Pfeiffer HK, Mellert HS, Stanek TJ, Sussman RT, Kumari A, Yu D, Rigoutsos I, Thomas-Tikhonenko A, Seidel HE, Chodosh LA, Packham G, Baserga R, McMahon SB. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Molecular and Cellular Biology. 31: 5037-45. PMID 21986497 DOI: 10.1128/Mcb.06297-11  0.649
2011 Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U. Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Molecular Cell. 42: 584-96. PMID 21658600 DOI: 10.1016/J.Molcel.2011.03.033  0.687
2011 Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ, Schultz DC, McMahon SB. Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis. The Journal of Biological Chemistry. 286: 4264-70. PMID 21148320 DOI: 10.1074/Jbc.M110.184663  0.747
2011 La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. Regulation of microRNA-145 by growth arrest and differentiation. Experimental Cell Research. 317: 488-95. PMID 21111732 DOI: 10.1016/J.Yexcr.2010.11.010  0.569
2010 Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 18: 329-40. PMID 20951943 DOI: 10.1016/J.Ccr.2010.08.012  0.615
2009 Mellert HS, McMahon SB. hMOF, a KAT(8) with many lives. Molecular Cell. 36: 174-5. PMID 19854127 DOI: 10.1016/J.Molcel.2009.10.005  0.579
2009 Mellert HS, McMahon SB. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells. Trends in Biochemical Sciences. 34: 571-8. PMID 19819149 DOI: 10.1016/J.Tibs.2009.06.010  0.638
2007 Mellert H, Sykes SM, Murphy ME, McMahon SB. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell Cycle (Georgetown, Tex.). 6: 1304-6. PMID 17534149 DOI: 10.4161/Cc.6.11.4343  0.723
2006 Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Molecular Cell. 24: 841-51. PMID 17189187 DOI: 10.1016/J.Molcel.2006.11.026  0.735
Low-probability matches (unlikely to be authored by this person)
2012 Den RB, Ciment S, Sharma A, Mellert H, McMahon S, Dicker AP, Knudsen KE. Abstract C15: RB status alters the response of prostate cancer to ionizing radiation Cancer Research. 72: C15-C15. DOI: 10.1158/1538-7445.Prca2012-C15  0.295
2004 Huyen Y, Zgheib O, Ditullio RA, Gorgoulis VG, Zacharatos P, Petty TJ, Sheston EA, Mellert HS, Stavridi ES, Halazonetis TD. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature. 432: 406-11. PMID 15525939 DOI: 10.1038/Nature03114  0.264
2024 Thangavel C, Boopathi E, Ciment S, Liu Y, O'Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. Correction: The Retinoblastoma Tumor Suppressor Modulates DNA Repair and Radioresponsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 30: 5695. PMID 39676540 DOI: 10.1158/1078-0432.CCR-24-3735  0.244
2011 Sotillo E, Laver T, Mellert H, Schelter JM, Cleary MA, McMahon S, Thomas-Tikhonenko A. Myc overexpression brings out unexpected antiapoptotic effects of miR-34a. Oncogene. 30: 2587-94. PMID 21297663 DOI: 10.1038/Onc.2010.634  0.236
2019 Mellert HS, Jackson L, Pestano GA. Development and correlative analysis of a TML assay in specimens with reference MSI and somatic variant results. Journal of Clinical Oncology. 37: 124-124. DOI: 10.1200/JCO.2019.37.8_SUPPL.124  0.223
2017 Mellert H, Foreman T, Jackson L, Maar D, Thurston S, Koch K, Weaver A, Cooper S, Dupuis N, Sathyanarayana UG, Greer J, Hahn W, Shelton D, Stonemetz P, Pestano GA. Development and Clinical Utility of a Blood-Based Test Service for the Rapid Identification of Actionable Mutations in Non-Small Cell Lung Carcinoma. The Journal of Molecular Diagnostics : Jmd. 19: 404-416. PMID 28433077 DOI: 10.1016/j.jmoldx.2016.11.004  0.155
2018 Amann A, Gamerith G, Bader A, Hahn W, Tschida C, Cope T, Audetat A, Mellert H, Pestano G, Zwierzina H. P3.04-01 Combined Plasma cfDNA Mutations and a Serum Proteomic Signature may Identify Non-Responders to Anti PD-1 Treatment in NSCLC Journal of Thoracic Oncology. 13: S922. DOI: 10.1016/j.jtho.2018.08.1708  0.144
2019 Bowling M, Arastu H, Edwards V, Jackson L, Thurston S, Reese J, Mellert H, Pestano G, Walker P. Longitudinal monitoring for the emergence of epidermal growth factor C797S resistance mutations in non-small cell lung cancer using blood-based droplet digital PCR. Cancer Drug Resistance (Alhambra, Calif.). 2: 912-916. PMID 35582570 DOI: 10.20517/cdr.2019.53  0.141
2021 Mellert H, Reese J, Jackson L, Maxwell V, Tschida C, Pestano GA. Targeted Next-Generation Sequencing of Liquid Biopsy Samples from Patients with NSCLC. Diagnostics (Basel, Switzerland). 11. PMID 33494470 DOI: 10.3390/diagnostics11020155  0.13
2017 Mellert HS, Jackson L, Pestano GA. PDL1 test to assess the dynamic range of mRNA expression from platelet enriched plasma in patients with NSCLC. Journal of Clinical Oncology. 35: e23063-e23063. DOI: 10.1200/JCO.2017.35.15_SUPPL.E23063  0.122
2022 Audetat A, Tschida C, Kreston S, Stephen A, D'Alessio B, Bondy M, Jackson L, Mellert H, Givens N, Sathyanarayana UG, Pestano GA. Analytic and Clinical Validation of a Pan-Cancer NGS Liquid Biopsy Test for the Detection of Copy Number Amplifications, Fusions and Exon Skipping Variants. Diagnostics (Basel, Switzerland). 12. PMID 35328282 DOI: 10.3390/diagnostics12030729  0.118
2017 Mellert HS, Jackson L, Tompkins C, Lodge A, Pestano GA. Development of DDPCR blood-based diagnostic tests that simultaneously measure mRNA expression from immune and cancer cells. Journal of Clinical Oncology. 35: 22-22. DOI: 10.1200/jco.2017.35.7_suppl.22  0.114
2018 Mellert HS, Alexander KE, Jackson LP, Pestano GA. A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction. Journal of Visualized Experiments : Jove. PMID 29683453 DOI: 10.3791/57079  0.111
2020 Jackson LP, Tjoa BA, Mellert H, Pestano GA. Development of a TCR beta repertoire assay for profiling liquid biopsies from NSCLC donors. Cancer Drug Resistance (Alhambra, Calif.). 3: 563-571. PMID 35582444 DOI: 10.20517/cdr.2020.07  0.11
2020 Kaiser NK, Steers M, Nichols CM, Mellert H, Pestano GA. Design and Characterization of a Novel Blood Collection and Transportation Device for Proteomic Applications. Diagnostics (Basel, Switzerland). 10. PMID 33276497 DOI: 10.3390/diagnostics10121032  0.058
2016 Mellert HS, Jackson L, Koch K, Hahn W, Pestano GA. Targeted genomic profiling of blood from patients with NSCLC after classification with a poor prognosis. Journal of Clinical Oncology. 34: e23051-e23051. DOI: 10.1200/jco.2016.34.15_suppl.e23051  0.049
2018 Mellert HS, Jackson L, Pestano GA. Performance verification of a plasma-based PD-L1 test that reliably measures mRNA expression from patients with NCSLC. Journal of Clinical Oncology. 36: 156-156. DOI: 10.1200/JCO.2018.36.5_suppl.156  0.038
Hide low-probability matches.