| Year |
Citation |
Score |
| 2024 |
Wankowicz SA, Ravikumar A, Sharma S, Riley B, Raju A, Hogan DW, Flowers J, van den Bedem H, Keedy DA, Fraser JS. Automated multiconformer model building for X-ray crystallography and cryo-EM. Elife. 12. PMID 38904665 DOI: 10.7554/eLife.90606 |
0.333 |
|
| 2023 |
Du S, Wankowicz SA, Yabukarski F, Doukov T, Herschlag D, Fraser JS. Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods in Enzymology. 688: 223-254. PMID 37748828 DOI: 10.1016/bs.mie.2023.06.009 |
0.349 |
|
| 2023 |
Wolff AM, Nango E, Young ID, Brewster AS, Kubo M, Nomura T, Sugahara M, Owada S, Barad BA, Ito K, Bhowmick A, Carbajo S, Hino T, Holton JM, Im D, ... ... Fraser JS, et al. Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nature Chemistry. PMID 37723259 DOI: 10.1038/s41557-023-01329-4 |
0.642 |
|
| 2023 |
Wankowicz SA, Ravikumar A, Sharma S, Riley BT, Raju A, Hogan DW, van den Bedem H, Keedy DA, Fraser JS. Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM. Biorxiv : the Preprint Server For Biology. PMID 37425870 DOI: 10.1101/2023.06.28.546963 |
0.381 |
|
| 2023 |
Du S, Wankowicz SA, Yabukarski F, Doukov T, Herschlag D, Fraser JS. Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data. Biorxiv : the Preprint Server For Biology. PMID 37205593 DOI: 10.1101/2023.05.05.539620 |
0.349 |
|
| 2023 |
Madani A, Krause B, Greene ER, Subramanian S, Mohr BP, Holton JM, Olmos JL, Xiong C, Sun ZZ, Socher R, Fraser JS, Naik N. Large language models generate functional protein sequences across diverse families. Nature Biotechnology. PMID 36702895 DOI: 10.1038/s41587-022-01618-2 |
0.55 |
|
| 2023 |
Wych DC, Aoto PC, Vu L, Wolff AM, Mobley DL, Fraser JS, Taylor SS, Wall ME. Molecular-dynamics simulation methods for macromolecular crystallography. Acta Crystallographica. Section D, Structural Biology. 79: 50-65. PMID 36601807 DOI: 10.1107/S2059798322011871 |
0.334 |
|
| 2022 |
Correy GJ, Kneller DW, Phillips G, Pant S, Russi S, Cohen AE, Meigs G, Holton JM, Gahbauer S, Thompson MC, Ashworth A, Coates L, Kovalevsky A, Meilleur F, Fraser JS. The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Science Advances. 8: eabo5083. PMID 35622909 DOI: 10.1126/sciadv.abo5083 |
0.628 |
|
| 2022 |
Wankowicz SA, de Oliveira SH, Hogan DW, van den Bedem H, Fraser JS. Ligand binding remodels protein side chain conformational heterogeneity. Elife. 11. PMID 35312477 DOI: 10.7554/eLife.74114 |
0.315 |
|
| 2022 |
Correy GJ, Kneller DW, Phillips G, Pant S, Russi S, Cohen AE, Meigs G, Holton JM, Gahbauer S, Thompson MC, Ashworth A, Coates L, Kovalevsky A, Meilleur F, Fraser JS. The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature. Biorxiv : the Preprint Server For Biology. PMID 35169801 DOI: 10.1101/2022.02.07.479477 |
0.624 |
|
| 2021 |
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, ... ... Fraser JS, et al. Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Science Advances. 7. PMID 33853786 DOI: 10.1126/sciadv.abf8711 |
0.614 |
|
| 2020 |
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Martins LC, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, ... ... Fraser JS, et al. Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking. Biorxiv : the Preprint Server For Biology. PMID 33269349 DOI: 10.1101/2020.11.24.393405 |
0.609 |
|
| 2020 |
Riley BT, Wankowicz SA, de Oliveira SHP, van Zundert GCP, Hogan DW, Fraser JS, Keedy DA, van den Bedem H. qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps. Protein Science : a Publication of the Protein Society. PMID 33210433 DOI: 10.1002/pro.4001 |
0.332 |
|
| 2020 |
Pan X, Thompson MC, Zhang Y, Liu L, Fraser JS, Kelly MJS, Kortemme T. Expanding the space of protein geometries by computational design of de novo fold families. Science (New York, N.Y.). 369: 1132-1136. PMID 32855341 DOI: 10.1126/Science.Abc0881 |
0.35 |
|
| 2020 |
Wolff AM, Young ID, Sierra RG, Brewster AS, Martynowycz MW, Nango E, Sugahara M, Nakane T, Ito K, Aquila A, Bhowmick A, Biel JT, Carbajo S, Cohen AE, Cortez S, ... ... Fraser JS, et al. Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals. Iucrj. 7: 306-323. PMID 32148858 DOI: 10.1107/S205225252000072X |
0.385 |
|
| 2020 |
Stojković V, Myasnikov AG, Young ID, Frost A, Fraser JS, Fujimori DG. Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit. Nucleic Acids Research. PMID 31989172 DOI: 10.1093/Nar/Gkaa037 |
0.376 |
|
| 2020 |
Barad BA, Liu L, Diaz RE, Basilio R, Van Dyken SJ, Locksley RM, Fraser JS. Differences in the chitinolytic activity of mammalian chitinases on soluble and insoluble substrates. Protein Science : a Publication of the Protein Society. PMID 31930591 DOI: 10.1002/Pro.3822 |
0.315 |
|
| 2019 |
Wych DC, Fraser JS, Mobley DL, Wall ME. Liquid-like and rigid-body motions in molecular-dynamics simulations of a crystalline protein. Structural Dynamics (Melville, N.Y.). 6: 064704. PMID 31867408 DOI: 10.1063/1.5132692 |
0.375 |
|
| 2019 |
Dasgupta M, Budday D, de Oliveira SHP, Madzelan P, Marchany-Rivera D, Seravalli J, Hayes B, Sierra RG, Boutet S, Hunter MS, Alonso-Mori R, Batyuk A, Wierman J, Lyubimov A, Brewster AS, ... ... Fraser JS, et al. Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31801874 DOI: 10.1073/pnas.1901864116 |
0.435 |
|
| 2019 |
Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. Computational design of a modular protein sense-response system. Science (New York, N.Y.). 366: 1024-1028. PMID 31754004 DOI: 10.1126/Science.Aax8780 |
0.335 |
|
| 2019 |
Thompson MC, Barad BA, Wolff AM, Sun Cho H, Schotte F, Schwarz DMC, Anfinrud P, Fraser JS. Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme. Nature Chemistry. PMID 31527847 DOI: 10.1038/S41557-019-0329-3 |
0.443 |
|
| 2019 |
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Löhr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E. Effects of α-tubulin acetylation on microtubule structure and stability. Proceedings of the National Academy of Sciences of the United States of America. PMID 31072936 DOI: 10.1073/Pnas.1900441116 |
0.352 |
|
| 2019 |
Hu S, Offenbacher AR, Thompson EM, Gee CL, Wilcoxen J, Carr CAM, Prigozhin DM, Yang V, Alber T, Britt RD, Fraser JS, Klinman JP. Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network. Journal of the American Chemical Society. PMID 30645119 DOI: 10.1021/Jacs.8B10992 |
0.631 |
|
| 2019 |
Thompson MC, Wolff AM, Nango E, Kubo M, Young ID, Nakane T, Sugahara M, Tanaka R, Ito K, Brewster AS, Sierra RG, Yumoto F, Nomura T, Owada S, Hino T, ... ... Fraser JS, et al. Turning up the heat on dynamic proteins: observing molecular motion in real time with temperature-jump X-ray crystallography Acta Crystallographica Section a Foundations and Advances. 75: a166-a166. DOI: 10.1107/S0108767319098349 |
0.389 |
|
| 2019 |
Wolff AM, Young ID, Sierra RG, Brewster AS, Martynowycz MW, Aquila A, Nango E, Nakane T, Koralek JD, Sugahara M, Tanaka R, Zhao W, Ito K, Woldeyes RA, Biel JT, ... ... Fraser JS, et al. Optimizing and evaluating protein microcrystallography experiments: strengths and weaknesses of X-rays and electrons Acta Crystallographica Section a Foundations and Advances. 75: a394-a394. DOI: 10.1107/S0108767319096156 |
0.345 |
|
| 2018 |
van Zundert G, Hudson BM, de Oliveira S, Keedy DA, Fonseca R, Heliou A, Suresh P, Borrelli K, Day T, Fraser J, van den Bedem H. qFit-ligand reveals widespread conformational heterogeneity of drug-like molecules in X-ray electron density maps. Journal of Medicinal Chemistry. PMID 30457858 DOI: 10.2210/Pdb6Dmj/Pdb |
0.429 |
|
| 2018 |
Herzik MA, Fraser JS, Lander GC. A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality. Structure (London, England : 1993). PMID 30449687 DOI: 10.1016/J.Str.2018.10.003 |
0.302 |
|
| 2018 |
Keedy DA, Hill ZB, Biel JT, Kang E, Rettenmaier TJ, Brandao-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife. 7. PMID 29877794 DOI: 10.7554/Elife.36307 |
0.478 |
|
| 2018 |
Otten R, Liu L, Kenner LR, Clarkson MW, Mavor D, Tawfik DS, Kern D, Fraser JS. Rescue of conformational dynamics in enzyme catalysis by directed evolution. Nature Communications. 9: 1314. PMID 29615624 DOI: 10.1038/S41467-018-03562-9 |
0.467 |
|
| 2018 |
Wall ME, Wolff AM, Fraser JS. Bringing diffuse X-ray scattering into focus. Current Opinion in Structural Biology. 50: 109-116. PMID 29455056 DOI: 10.1016/J.Sbi.2018.01.009 |
0.337 |
|
| 2018 |
Brunger AT, Fraser JS. Decision letter: Automated cryo-EM structure refinement using correlation-driven molecular dynamics Elife. DOI: 10.7554/Elife.43542.038 |
0.305 |
|
| 2017 |
Acker TM, Gable JE, Bohn MF, Jaishankar P, Thompson MC, Fraser JS, Renslo AR, Craik CS. Allosteric Inhibitors, Crystallography and Comparative Analysis Reveal Network of Coordinated Movement Across Human Herpesvirus Proteases. Journal of the American Chemical Society. PMID 28759216 DOI: 10.1021/Jacs.7B04030 |
0.415 |
|
| 2017 |
Offenbacher AR, Hu S, Poss EM, Carr CAM, Scouras AD, Prigozhin DM, Iavarone AT, Palla A, Alber T, Fraser JS, Klinman JP. Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling. Acs Central Science. 3: 570-579. PMID 28691068 DOI: 10.1021/Acscentsci.7B00142 |
0.625 |
|
| 2017 |
Biel JT, Thompson MC, Cunningham CN, Corn JE, Fraser JS. Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin. Structure (London, England : 1993). PMID 28416112 DOI: 10.1016/J.Str.2017.03.009 |
0.4 |
|
| 2017 |
Russi S, González A, Kenner LR, Keedy DA, Fraser JS, van den Bedem H. Conformational variation of proteins at room temperature is not dominated by radiation damage. Journal of Synchrotron Radiation. 24: 73-82. PMID 28009548 DOI: 10.1107/S1600577516017343 |
0.327 |
|
| 2017 |
Babcock NS, Sivak DA, Keedy D, Fraser JS. Model Comparison to Identify Structural Heterogeneity in Protein X-Ray Crystallography Biophysical Journal. 112: 486a. DOI: 10.1016/J.Bpj.2016.11.2628 |
0.68 |
|
| 2016 |
Wang RY, Song Y, Barad BA, Cheng Y, Fraser JS, DiMaio F. Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta. Elife. 5. PMID 27669148 DOI: 10.7554/Elife.17219 |
0.325 |
|
| 2016 |
Van Benschoten AH, Liu L, Gonzalez A, Brewster AS, Sauter NK, Fraser JS, Wall ME. Measuring and modeling diffuse scattering in protein X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035972 DOI: 10.1073/Pnas.1524048113 |
0.365 |
|
| 2016 |
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Fraser JS, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882 |
0.303 |
|
| 2016 |
Baxter EL, Aguila L, Alonso-Mori R, Barnes CO, Bonagura CA, Brehmer W, Brunger AT, Calero G, Caradoc-Davies TT, Chatterjee R, Degrado WF, Fraser JS, Ibrahim M, Kern J, Kobilka BK, et al. High-density grids for efficient data collection from multiple crystals. Acta Crystallographica. Section D, Structural Biology. 72: 2-11. PMID 26894529 DOI: 10.1107/S2059798315020847 |
0.336 |
|
| 2016 |
Cimermancic P, Weinkam P, Rettenmaier TJ, Bichmann L, Keedy DA, Woldeyes RA, Schneidmann D, Demerdash ON, Mitchell JC, Wells JA, Fraser JS, Sali A. CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites. Journal of Molecular Biology. PMID 26854760 DOI: 10.1016/J.Jmb.2016.01.029 |
0.398 |
|
| 2015 |
Thomaston JL, Alfonso-Prieto M, Woldeyes RA, Fraser JS, Klein ML, Fiorin G, DeGrado WF. High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction. Proceedings of the National Academy of Sciences of the United States of America. 112: 14260-5. PMID 26578770 DOI: 10.1073/Pnas.1518493112 |
0.338 |
|
| 2015 |
Keedy DA, Fraser JS, van den Bedem H. Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit. Plos Computational Biology. 11: e1004507. PMID 26506617 DOI: 10.1371/Journal.Pcbi.1004507 |
0.46 |
|
| 2015 |
Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, ... ... Fraser JS, et al. Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography. Elife. 4. PMID 26422513 DOI: 10.7554/Elife.07574 |
0.686 |
|
| 2015 |
Barad BA, Echols N, Wang RY, Cheng Y, DiMaio F, Adams PD, Fraser JS. EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy. Nature Methods. 12: 943-6. PMID 26280328 DOI: 10.1038/Nmeth.3541 |
0.313 |
|
| 2015 |
Urzhumtsev A, Afonine PV, Van Benschoten AH, Fraser JS, Adams PD. From deep TLS validation to ensembles of atomic models built from elemental motions. Acta Crystallographica. Section D, Biological Crystallography. 71: 1668-83. PMID 26249348 DOI: 10.1107/S1399004715011426 |
0.306 |
|
| 2015 |
Van Benschoten AH, Afonine PV, Terwilliger TC, Wall ME, Jackson CJ, Sauter NK, Adams PD, Urzhumtsev A, Fraser JS. Predicting X-ray diffuse scattering from translation-libration-screw structural ensembles. Acta Crystallographica. Section D, Biological Crystallography. 71: 1657-67. PMID 26249347 DOI: 10.1107/S1399004715007415 |
0.363 |
|
| 2015 |
Fischer M, Shoichet BK, Fraser JS. One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites. Chembiochem : a European Journal of Chemical Biology. PMID 26032594 DOI: 10.1002/Cbic.201500196 |
0.43 |
|
| 2015 |
Dellus-Gur E, Elias M, Caselli E, Prati F, Salverda ML, de Visser JA, Fraser JS, Tawfik DS. Negative Epistasis and Evolvability in TEM-1 β-Lactamase-The Thin Line between an Enzyme's Conformational Freedom and Disorder. Journal of Molecular Biology. 427: 2396-409. PMID 26004540 DOI: 10.1016/J.Jmb.2015.05.011 |
0.375 |
|
| 2015 |
van den Bedem H, Fraser JS. Integrative, dynamic structural biology at atomic resolution--it's about time. Nature Methods. 12: 307-18. PMID 25825836 DOI: 10.1038/Nmeth.3324 |
0.435 |
|
| 2015 |
Bhabha G, Biel JT, Fraser JS. Keep on moving: discovering and perturbing the conformational dynamics of enzymes. Accounts of Chemical Research. 48: 423-30. PMID 25539415 DOI: 10.1021/Ar5003158 |
0.463 |
|
| 2015 |
Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Benschoten AHV, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, ... ... Fraser JS, et al. Author response: Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography Elife. DOI: 10.7554/Elife.07574.055 |
0.604 |
|
| 2015 |
Fischer M, Shoichet BK, Fraser JS. Inside Cover: One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites (ChemBioChem 11/2015) Chembiochem. 16: 1526-1526. DOI: 10.1002/Cbic.201590029 |
0.369 |
|
| 2014 |
Wall ME, Van Benschoten AH, Sauter NK, Adams PD, Fraser JS, Terwilliger TC. Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering. Proceedings of the National Academy of Sciences of the United States of America. 111: 17887-92. PMID 25453071 DOI: 10.1073/Pnas.1416744111 |
0.374 |
|
| 2014 |
Woldeyes RA, Sivak DA, Fraser JS. E pluribus unum, no more: from one crystal, many conformations. Current Opinion in Structural Biology. 28: 56-62. PMID 25113271 DOI: 10.1016/J.Sbi.2014.07.005 |
0.694 |
|
| 2014 |
Fischer M, Coleman RG, Fraser JS, Shoichet BK. Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nature Chemistry. 6: 575-83. PMID 24950326 DOI: 10.1038/Nchem.1954 |
0.364 |
|
| 2014 |
Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS. Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR. Structure (London, England : 1993). 22: 899-910. PMID 24882744 DOI: 10.1016/J.Str.2014.04.016 |
0.721 |
|
| 2014 |
Wall ME, Adams PD, Fraser JS, Sauter NK. Diffuse X-ray scattering to model protein motions. Structure (London, England : 1993). 22: 182-4. PMID 24507780 DOI: 10.1016/J.Str.2014.01.002 |
0.377 |
|
| 2014 |
Fenwick RB, van den Bedem H, Fraser JS, Wright PE. Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR. Proceedings of the National Academy of Sciences of the United States of America. 111: E445-54. PMID 24474795 DOI: 10.1073/Pnas.1323440111 |
0.487 |
|
| 2014 |
Lang PT, Holton JM, Fraser JS, Alber T. Protein structural ensembles are revealed by redefining X-ray electron density noise Proceedings of the National Academy of Sciences of the United States of America. 111: 237-242. PMID 24363322 DOI: 10.1073/Pnas.1302823110 |
0.734 |
|
| 2014 |
Woldeyes RA, Sivak DA, Fraser JS. E pluribus unum, no more: From one crystal, many conformations Current Opinion in Structural Biology. 28: 56-62. DOI: 10.1016/j.sbi.2014.07.005 |
0.595 |
|
| 2014 |
Keedy D, van den Bedem H, Rettenmaier J, Wells J, Fraser J. Discovering and Manipulating Protein Conformational Heterogeneity and Function Biophysical Journal. 106: 635a-636a. DOI: 10.1016/J.Bpj.2013.11.3515 |
0.477 |
|
| 2014 |
Wall ME, Terwilliger TC, Fraser JS, Adams PD, Sauter NK, VanBenschoten A. Diffuse X-Ray Scattering for Ensemble Modeling of Crystalline Proteins Biophysical Journal. 106: 384a. DOI: 10.1016/J.Bpj.2013.11.2171 |
0.386 |
|
| 2013 |
Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, et al. From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. Cell. 154: 775-88. PMID 23932120 DOI: 10.1016/J.Cell.2013.07.033 |
0.307 |
|
| 2013 |
van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS. Automated identification of functional dynamic contact networks from X-ray crystallography. Nature Methods. 10: 896-902. PMID 23913260 DOI: 10.1038/Nmeth.2592 |
0.465 |
|
| 2013 |
Ollikainen N, Smith CA, Fraser JS, Kortemme T. Flexible backbone sampling methods to model and design protein alternative conformations. Methods in Enzymology. 523: 61-85. PMID 23422426 DOI: 10.1016/B978-0-12-394292-0.00004-7 |
0.415 |
|
| 2013 |
Fraser JS, Gross JD, Krogan NJ. From systems to structure: bridging networks and mechanism. Molecular Cell. 49: 222-31. PMID 23352243 DOI: 10.1016/J.Molcel.2013.01.003 |
0.322 |
|
| 2012 |
Vila JA, Sue SC, Fraser JS, Scheraga HA, Dyson HJ. CheShift-2 resolves a local inconsistency between two X-ray crystal structures. Journal of Biomolecular Nmr. 54: 193-8. PMID 22945426 DOI: 10.1007/S10858-012-9663-0 |
0.4 |
|
| 2012 |
Beltrao P, Albanèse V, Kenner LR, Swaney DL, Burlingame A, Villén J, Lim WA, Fraser JS, Frydman J, Krogan NJ. Systematic functional prioritization of protein posttranslational modifications. Cell. 150: 413-25. PMID 22817900 DOI: 10.1016/J.Cell.2012.05.036 |
0.339 |
|
| 2012 |
Kapp GT, Liu S, Stein A, Wong DT, Reményi A, Yeh BJ, Fraser JS, Taunton J, Lim WA, Kortemme T. Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proceedings of the National Academy of Sciences of the United States of America. 109: 5277-82. PMID 22403064 DOI: 10.1073/Pnas.1114487109 |
0.325 |
|
| 2011 |
Fraser JS, Van Den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T. Accessing protein conformational ensembles using room-temperature X-ray crystallography Proceedings of the National Academy of Sciences of the United States of America. 108: 16247-16252. PMID 21918110 DOI: 10.1073/Pnas.1111325108 |
0.761 |
|
| 2011 |
Fraser JS, Jackson CJ. Mining electron density for functionally relevant protein polysterism in crystal structures Cellular and Molecular Life Sciences. 68: 1829-1841. PMID 21190057 DOI: 10.1007/S00018-010-0611-4 |
0.475 |
|
| 2010 |
Lang PT, Ng HL, Fraser JS, Corn JE, Echols N, Sales M, Holton JM, Alber T. Automated electron-density sampling reveals widespread conformational polymorphism in proteins. Protein Science : a Publication of the Protein Society. 19: 1420-31. PMID 20499387 DOI: 10.1002/Pro.423 |
0.76 |
|
| 2009 |
Fraser JS, Clarkson MW, Degnan SC, Erion R, Kern D, Alber T. Hidden alternative structures of proline isomerase essential for catalysis Nature. 462: 669-673. PMID 19956261 DOI: 10.1038/Nature08615 |
0.674 |
|
| 2009 |
Clarkson MW, Fraser J, Alber T, Kern D. Cyclophilin Dynamics and Catalysis are Mechanistically Linked Biophysical Journal. 96: 555a. DOI: 10.1016/J.Bpj.2008.12.3644 |
0.624 |
|
| 2007 |
Fraser JS, Merlie JP, Echols N, Weisfield SR, Mignot T, Wemmer DE, Zusman DR, Alber T. An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS. Molecular Microbiology. 65: 319-32. PMID 17573816 DOI: 10.1111/J.1365-2958.2007.05785.X |
0.609 |
|
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