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Julie A. Zorn, Ph.D. - Publications

Affiliations: 
Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Area:
molecular recognition
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Zorn JA, Wang Q, Fujimura E, Barros T, Kuriyan J. Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220). Plos One. 10: e0121177. PMID 25837374 DOI: 10.1371/Journal.Pone.0121177  0.663
2015 Wang Q, Vogan EM, Nocka LM, Rosen CE, Zorn JA, Harrison SC, Kuriyan J. Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife. 4. PMID 25699547 DOI: 10.7554/Elife.06074  0.592
2015 Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on the regulation of the epidermal growth factor receptor. Annual Review of Biochemistry. 84: 739-64. PMID 25621509 DOI: 10.1146/Annurev-Biochem-060614-034402  0.635
2015 Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on the regulation of the epidermal growth factor receptor Annual Review of Biochemistry. 84: 739-764. DOI: 10.1146/annurev-biochem-060614-034402  0.58
2014 Wang Q, Zorn JA, Kuriyan J. A structural at~las of kinases inhibited by clinically approved drugs Methods in Enzymology. 548: 23-67. PMID 25399641 DOI: 10.1016/B978-0-12-397918-6.00002-1  0.575
2014 Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/Nchembio.1639  0.565
2014 Julien O, Kampmann M, Bassik MC, Venditto VJ, Zorn JA, Rheingold AL, Weissman JS, Wells JA. Unraveling the Mechanism of Cell Death Induced by Chemical and Protein Fibrils Biophysical Journal. 106: 40a. DOI: 10.1016/J.Bpj.2013.11.297  0.562
2012 Zorn JA, Wolan DW, Agard NJ, Wells JA. Fibrils colocalize caspase-3 with procaspase-3 to foster maturation. The Journal of Biological Chemistry. 287: 33781-95. PMID 22872644 DOI: 10.1074/Jbc.M112.386128  0.708
2011 Zorn JA, Wille H, Wolan DW, Wells JA. Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation. Journal of the American Chemical Society. 133: 19630-3. PMID 22066605 DOI: 10.1021/Ja208350U  0.714
2010 Zorn JA, Wells JA. Turning enzymes ON with small molecules. Nature Chemical Biology. 6: 179-188. PMID 20154666 DOI: 10.1038/Nchembio.318  0.608
2010 Wells JA, Wolan D, Zorn J, Datta D, Gray D, Sadowsky J. Abstract SY11-03: Turning enzymes on with small molecules Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Sy11-03  0.688
2009 Wolan DW, Zorn JA, Gray DC, Wells JA. Small-molecule activators of a proenzyme. Science (New York, N.Y.). 326: 853-8. PMID 19892984 DOI: 10.1126/Science.1177585  0.72
2007 Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BC. Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds. The Journal of General Virology. 88: 1392-401. PMID 17374787 DOI: 10.1099/Vir.0.82601-0  0.309
2007 Caffrey CR, Steverding D, Swenerton RK, Kelly B, Walshe D, Debnath A, Zhou YM, Doyle PS, Fafarman AT, Zorn JA, Land KM, Beauchene J, Schreiber K, Moll H, Ponte-Sucre A, et al. Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro. Antimicrobial Agents and Chemotherapy. 51: 2164-72. PMID 17371810 DOI: 10.1128/Aac.01418-06  0.35
2007 May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE. Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics. Journal of Medicinal Chemistry. 50: 65-73. PMID 17201410 DOI: 10.1021/Jm061045Z  0.38
2006 May BC, Witkop J, Sherrill J, Anderson MO, Madrid PB, Zorn JA, Prusiner SB, Cohen FE, Guy RK. Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells. Bioorganic & Medicinal Chemistry Letters. 16: 4913-6. PMID 16860557 DOI: 10.1016/J.Bmcl.2006.06.050  0.341
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