John Kuriyan - Publications

Affiliations: 
University of California, Berkeley, Berkeley, CA 
Area:
Structural Biology of Cellular Signal Transduction and DNA Replication
Website:
http://chemistry.berkeley.edu/faculty/chem/kuriyan

245 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hobbs HT, Shah NH, Shoemaker SR, Amacher JF, Marqusee S, Kuriyan J. Saturation mutagenesis of a predicted ancestral Syk-family kinase. Protein Science : a Publication of the Protein Society. 31: e4411. PMID 36173161 DOI: 10.1002/pro.4411  0.736
2022 Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, ... Kuriyan J, et al. Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210990119. PMID 36122200 DOI: 10.1073/pnas.2210990119  0.479
2022 Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, ... Kuriyan J, et al. Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein. Biorxiv : the Preprint Server For Biology. PMID 35982670 DOI: 10.1101/2022.08.11.503553  0.479
2022 Hidalgo F, Nocka LM, Shah NH, Gorday K, Latorraca NR, Bandaru P, Templeton S, Lee D, Karandur D, Pelton JG, Marqusee S, Wemmer D, Kuriyan J. A saturation-mutagenesis analysis of the interplay between stability and activation in Ras. Elife. 11. PMID 35272765 DOI: 10.7554/eLife.76595  0.793
2021 Hobbs HT, Shah NH, Badroos JM, Gee CL, Marqusee S, Kuriyan J. Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases. Protein Science : a Publication of the Protein Society. PMID 34601763 DOI: 10.1002/pro.4199  0.748
2021 Kondo Y, Paul JW, Subramaniam S, Kuriyan J. New insights into Raf regulation from structural analyses. Current Opinion in Structural Biology. 71: 223-231. PMID 34454301 DOI: 10.1016/j.sbi.2021.07.005  0.798
2021 Leurs U, Klein AB, McSpadden ED, Griem-Krey N, Solbak SMØ, Houlton J, Villumsen IS, Vogensen SB, Hamborg L, Gauger SJ, Palmelund LB, Larsen ASG, Shehata MA, Kelstrup CD, Olsen JV, ... ... Kuriyan J, et al. GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34330837 DOI: 10.1073/pnas.2108079118  0.3
2020 Karandur D, Bhattacharyya M, Xia Z, Lee YK, Muratcioglu S, McAffee D, McSpadden E, Qiu B, Groves JT, Williams ER, Kuriyan J. Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase. Elife. 9. PMID 32902386 DOI: 10.7554/Elife.57784  0.392
2020 Mena EL, Jevtić P, Greber BJ, Gee CL, Lew BG, Akopian D, Nogales E, Kuriyan J, Rape M. Structural basis for dimerization quality control. Nature. PMID 32814905 DOI: 10.1038/S41586-020-2636-7  0.321
2020 Cofsky JC, Karandur D, Huang CJ, Witte IP, Kuriyan J, Doudna JA. CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks. Elife. 9. PMID 32519675 DOI: 10.7554/Elife.55143  0.3
2020 Bhattacharyya M, Lee YK, Muratcioglu S, Qiu B, Nyayapati P, Schulman H, Groves JT, Kuriyan J. Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation. Elife. 9. PMID 32149607 DOI: 10.7554/Elife.53670  0.44
2020 Nocka LM, Chung JK, Decker A, Kadlecek T, Weiss A, Kuriyan J, Groves JT. Bruton's Tyrosine Kinase Membrane Dynamics and Signaling Biophysical Journal. 118: 560a-561a. DOI: 10.1016/J.Bpj.2019.11.3060  0.626
2019 Bhattacharyya M, Karandur D, Kuriyan J. Structural Insights into the Regulation of Ca/Calmodulin-Dependent Protein Kinase II (CaMKII). Cold Spring Harbor Perspectives in Biology. PMID 31653643 DOI: 10.1101/Cshperspect.A035147  0.46
2019 Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nature Immunology. PMID 31611699 DOI: 10.1038/S41590-019-0502-2  0.737
2019 Kondo Y, Ognjenović J, Banerjee S, Karandur D, Merk A, Kulhanek K, Wong K, Roose JP, Subramaniam S, Kuriyan J. Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Science (New York, N.Y.). 366: 109-115. PMID 31604311 DOI: 10.1126/Science.Aay0543  0.471
2019 Chung JK, Nocka LM, Decker A, Wang Q, Kadlecek TA, Weiss A, Kuriyan J, Groves JT. Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization. Proceedings of the National Academy of Sciences of the United States of America. PMID 31076553 DOI: 10.1073/Pnas.1819309116  0.704
2019 McSpadden ED, Xia Z, Chi CC, Susa AC, Shah NH, Gee CL, Williams ER, Kuriyan J. Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/Calmodulin-dependent protein kinase II. Protein Science : a Publication of the Protein Society. PMID 30942928 DOI: 10.2210/Pdb6Of8/Pdb  0.667
2019 Simonetta KR, Taygerly J, Boyle K, Basham SE, Padovani C, Lou Y, Cummins TJ, Yung SL, von Soly SK, Kayser F, Kuriyan J, Rape M, Cardozo M, Gallop MA, Bence NF, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications. 10: 1402. PMID 30926793 DOI: 10.1038/S41467-019-09358-9  0.77
2019 Huang WYC, Alvarez S, Kondo Y, Lee YK, Chung JK, Lam HYM, Biswas KH, Kuriyan J, Groves JT. A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS. Science (New York, N.Y.). 363: 1098-1103. PMID 30846600 DOI: 10.1126/Science.Aau5721  0.385
2019 Shah NH, Kuriyan J. Understanding molecular mechanisms in cell signaling through natural and artificial sequence variation. Nature Structural & Molecular Biology. 26: 25-34. PMID 30598552 DOI: 10.1038/S41594-018-0175-9  0.567
2019 Alvarez S, Huang WY, Monatrice Lam HY, Low-Nam ST, Kwang Lee Y, Chung JK, Hansen SD, Kondo Y, Biswas KH, Kuriyan J, Groves JT. Total Reconstitution of Receptor-Mediated Ras Activation by SOS in Vitro Reveals Kinetic and Conformational Layers of Regulation in MAPK Signaling Biophysical Journal. 116: 531a-532a. DOI: 10.1016/J.Bpj.2018.11.2861  0.378
2018 Shah NH, Amacher JF, Nocka LM, Kuriyan J. The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases. Critical Reviews in Biochemistry and Molecular Biology. 1-29. PMID 30183386 DOI: 10.1080/10409238.2018.1495173  0.688
2018 Cantor AJ, Shah NH, Kuriyan J. Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites. Proceedings of the National Academy of Sciences of the United States of America. PMID 30012625 DOI: 10.1073/Pnas.1803598115  0.676
2018 Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. Nature Immunology. PMID 29915297 DOI: 10.1038/S41590-018-0131-1  0.782
2018 Bandaru P, Kondo Y, Kuriyan J. The Interdependent Activation of Son-of-Sevenless and Ras. Cold Spring Harbor Perspectives in Medicine. PMID 29610148 DOI: 10.1101/Cshperspect.A031534  0.816
2018 Shah NH, Löbel M, Weiss A, Kuriyan J. Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen. Elife. 7. PMID 29547119 DOI: 10.7554/Elife.35190  0.774
2018 Amacher JF, Hobbs HT, Cantor AC, Shah L, Rivero MJ, Mulchand SA, Kuriyan J. Phosphorylation Control of the Ubiquitin Ligase Cbl is Conserved in Choanoflagellates. Protein Science : a Publication of the Protein Society. PMID 29498112 DOI: 10.1002/Pro.3397  0.464
2018 Shah NH, Löbel M, Weiss A, Kuriyan J. Author response: Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen Elife. DOI: 10.7554/Elife.35190.025  0.713
2018 Hobbs HT, Shah N, Marqusee S, Kuriyan J. Dissecting the Divergent Functions and Dynamics of ZAP-70 and SYK Biophysical Journal. 114: 572a. DOI: 10.1016/J.Bpj.2017.11.3129  0.653
2018 Chung JK, Nocka LM, Kwang Lee Y, Kuriyan J, Groves JT. Measuring Membrane Surface Reactions by Diffusion: Dimerization of Btk PH Domain and K-Ras Biophysical Journal. 114: 558a. DOI: 10.1016/J.Bpj.2017.11.3054  0.32
2017 Vercoulen Y, Kondo Y, Iwig JS, Janssen A, White KA, Amini M, Barber DL, Kuriyan J, Roose JP. A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife. 6. PMID 28952923 DOI: 10.7554/Elife.29002  0.424
2017 Karandur D, Nawrotek A, Kuriyan J, Cherfils J. Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923919 DOI: 10.1073/Pnas.1707970114  0.372
2017 Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45. Molecular Cell. PMID 28735895 DOI: 10.1016/J.Molcel.2017.06.024  0.68
2017 Bandaru P, Shah NH, Bhattacharyya M, Barton JP, Kondo Y, Cofsky JC, Gee CL, Chakraborty AK, Kortemme T, Ranganathan R, Kuriyan J. Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife. 6. PMID 28686159 DOI: 10.7554/Elife.27810  0.8
2017 Vercoulen Y, Kondo Y, Iwig JS, Janssen AB, White KA, Amini M, Barber DL, Kuriyan J, Roose JP. Author response: A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1 Elife. DOI: 10.7554/Elife.29002.022  0.314
2017 Bandaru P, Shah NH, Bhattacharyya M, Barton JP, Kondo Y, Cofsky JC, Gee CL, Chakraborty AK, Kortemme T, Ranganathan R, Kuriyan J. Author response: Deconstruction of the Ras switching cycle through saturation mutagenesis Elife. DOI: 10.7554/Elife.27810.040  0.779
2017 Hobbs HT, Marqusee S, Kuriyan J. The Effects of Protein Dynamics on Immune System Signaling Pathways Biophysical Journal. 112: 63a. DOI: 10.1016/J.Bpj.2016.11.380  0.683
2016 Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. Journal of Biomolecular Screening. PMID 27932698 DOI: 10.1177/1087057116681407  0.776
2016 Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. Elife. 5. PMID 27700984 DOI: 10.7554/Elife.20105  0.812
2016 Huang WY, Yan Q, Lin WC, Chung JK, Hansen SD, Christensen SM, Tu HL, Kuriyan J, Groves JT. Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS. Proceedings of the National Academy of Sciences of the United States of America. PMID 27370798 DOI: 10.1073/Pnas.1602602113  0.776
2016 Huang Y, Bharill S, Karandur D, Peterson SM, Marita M, Shi X, Kaliszewski MJ, Smith AW, Isacoff EY, Kuriyan J. Molecular basis for multimerization in the activation of the epidermal growth factor receptor. Elife. 5. PMID 27017828 DOI: 10.7554/Elife.14107  0.486
2016 Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J. Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II. Elife. 5. PMID 26949248 DOI: 10.7554/Elife.13405  0.769
2016 Lorenz S, Bhattacharyya M, Feiler C, Rape M, Kuriyan J. Crystal Structure of a Ube2S-Ubiquitin Conjugate. Plos One. 11: e0147550. PMID 26828794 DOI: 10.1371/Journal.Pone.0147550  0.571
2016 Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Man Fu S, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. The Journal of Experimental Medicine. PMID 26783323 DOI: 10.1084/Jem.20150888  0.612
2016 Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. Author response: An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor Elife. DOI: 10.7554/Elife.20105.045  0.799
2016 Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J. Author response: Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II Elife. DOI: 10.7554/Elife.13405.039  0.619
2016 Huang WY, Yan Q, Lin W, Chung JK, Hansen SD, Christensen SM, Tu H, Kuriyan J, Groves JT. Protein Assembly on Membrane Surface alters the Dynamical Spectrum of Downstream Signaling Reactions Biophysical Journal. 110: 88a. DOI: 10.1016/J.Bpj.2015.11.534  0.763
2015 Kovacs E, Das R, Wang Q, Collier TS, Cantor A, Huang Y, Wong K, Mirza A, Barros T, Grob P, Jura N, Bose R, Kuriyan J. Analysis of the role of the C-terminal tail in the regulation of the epidermal growth factor receptor. Molecular and Cellular Biology. PMID 26124280 DOI: 10.1128/Mcb.00248-15  0.842
2015 Sjölin-Goodfellow H, Frushicheva MP, Ji Q, Cheng DA, Kadlecek TA, Cantor AJ, Kuriyan J, Chakraborty AK, Salomon AR, Weiss A. The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. Science Signaling. 8: ra49. PMID 25990959 DOI: 10.1126/Scisignal.2005596  0.673
2015 Zorn JA, Wang Q, Fujimura E, Barros T, Kuriyan J. Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220). Plos One. 10: e0121177. PMID 25837374 DOI: 10.1371/Journal.Pone.0121177  0.842
2015 Lorenz S, Deng P, Hantschel O, Superti-Furga G, Kuriyan J. Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity. The Biochemical Journal. 468: 283-91. PMID 25779001 DOI: 10.1042/Bj20141492  0.667
2015 Wang Q, Vogan EM, Nocka LM, Rosen CE, Zorn JA, Harrison SC, Kuriyan J. Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife. 4. PMID 25699547 DOI: 10.7554/Elife.06074  0.836
2015 Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on the regulation of the epidermal growth factor receptor. Annual Review of Biochemistry. 84: 739-64. PMID 25621509 DOI: 10.1146/Annurev-Biochem-060614-034402  0.826
2015 Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. The Biochemical Journal. 465: 149-61. PMID 25287889 DOI: 10.1042/Bj20140793  0.823
2015 Wang Q, Vogan EM, Nocka LM, Rosen CE, Zorn JA, Harrison SC, Kuriyan J. Author response: Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate Elife. DOI: 10.7554/Elife.06074.026  0.609
2015 Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on the regulation of the epidermal growth factor receptor Annual Review of Biochemistry. 84: 739-764. DOI: 10.1146/annurev-biochem-060614-034402  0.77
2014 Wang Q, Zorn JA, Kuriyan J. A structural at~las of kinases inhibited by clinically approved drugs Methods in Enzymology. 548: 23-67. PMID 25399641 DOI: 10.1016/B978-0-12-397918-6.00002-1  0.789
2014 Herzik MA, Jonnalagadda R, Kuriyan J, Marletta MA. Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proceedings of the National Academy of Sciences of the United States of America. 111: E4156-64. PMID 25253889 DOI: 10.1073/Pnas.1416936111  0.558
2014 Endres NF, Barros T, Cantor AJ, Kuriyan J. Emerging concepts in the regulation of the EGF receptor and other receptor tyrosine kinases. Trends in Biochemical Sciences. 39: 437-46. PMID 25242369 DOI: 10.1016/J.Tibs.2014.08.001  0.818
2014 Iversen L, Tu HL, Lin WC, Christensen SM, Abel SM, Iwig J, Wu HJ, Gureasko J, Rhodes C, Petit RS, Hansen SD, Thill P, Yu CH, Stamou D, Chakraborty AK, ... Kuriyan J, et al. Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics. Science (New York, N.Y.). 345: 50-4. PMID 24994643 DOI: 10.1126/Science.1250373  0.799
2014 Lasater EA, Lin KC, Wang Q, Quino McCreery M, Stewart WK, Damon LE, Perl AE, Jeschke GR, Sugita M, Carroll M, Kogan SC, Kuriyan J, Shah NP. Crenolanib is a selective type i pan-FLT3 inhibitor Catherine Choy Smith1,2 Proceedings of the National Academy of Sciences of the United States of America. 111: 5319-5324. PMID 24623852 DOI: 10.1073/Pnas.1320661111  0.493
2014 Stratton M, Lee IH, Bhattacharyya M, Christensen SM, Chao LH, Schulman H, Groves JT, Kuriyan J. Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity. Elife. 3: e02490. PMID 24520169 DOI: 10.7554/Elife.02490  0.818
2014 Stratton M, Lee IH, Bhattacharyya M, Christensen SM, Chao LH, Schulman H, Groves JT, Kuriyan J. Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity. Elife. 3: e01610. PMID 24473075 DOI: 10.7554/Elife.01610  0.823
2013 Iwig JS, Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer DE, Roose JP, Kuriyan J. Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife. 2: e00813. PMID 23908768 DOI: 10.7554/Elife.00813  0.72
2013 Lorenz S, Cantor AJ, Rape M, Kuriyan J. Macromolecular juggling by ubiquitylation enzymes. Bmc Biology. 11: 65. PMID 23800009 DOI: 10.1186/1741-7007-11-65  0.543
2013 Iwig JS, Kuriyan J. XFixing a hole where the ras gets in Cell. 153: X1191-1193. PMID 23746837 DOI: 10.1016/J.Cell.2013.05.029  0.307
2013 Engel K, Sasaki T, Wang Q, Kuriyan J. A highly efficient peptide substrate for EGFR activates the kinase by inducing aggregation. The Biochemical Journal. 453: 337-44. PMID 23734957 DOI: 10.1042/Bj20130537  0.525
2013 Barros T, Guenther J, Kelch B, Anaya J, Prabhakar A, O'Donnell M, Kuriyan J, Lamers MH. A structural role for the PHP domain in E. coli DNA polymerase III Bmc Structural Biology. 13. PMID 23672456 DOI: 10.1186/1472-6807-13-8  0.809
2013 Stratton MM, Chao LH, Schulman H, Kuriyan J. Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II. Current Opinion in Structural Biology. 23: 292-301. PMID 23632248 DOI: 10.1016/J.Sbi.2013.04.002  0.799
2013 Yan Q, Barros T, Visperas PR, Deindl S, Kadlecek TA, Weiss A, Kuriyan J. Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. Molecular and Cellular Biology. 33: 2188-201. PMID 23530057 DOI: 10.1128/Mcb.01637-12  0.832
2013 Arkhipov A, Shan Y, Das R, Endres NF, Eastwood MP, Wemmer DE, Kuriyan J, Shaw DE. Architecture and membrane interactions of the EGF receptor. Cell. 152: 557-69. PMID 23374350 DOI: 10.1016/J.Cell.2012.12.030  0.834
2013 Endres NF, Das R, Smith AW, Arkhipov A, Kovacs E, Huang Y, Pelton JG, Shan Y, Shaw DE, Wemmer DE, Groves JT, Kuriyan J. Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell. 152: 543-56. PMID 23374349 DOI: 10.1016/J.Cell.2012.12.032  0.81
2013 Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A. Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases Science Signaling. 6. PMID 23281368 DOI: 10.1126/Scisignal.2003220  0.684
2013 Iwig JS, Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer DE, Roose JP, Kuriyan J. Author response: Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1 Elife. DOI: 10.7554/Elife.00813.032  0.67
2013 Endres N, Das R, Smith A, Arkhipov A, Kovacs E, Huang Y, Pelton J, Shan Y, Shaw D, Wemmer D, Groves J, Kuriyan J. EGFR transmembrane - juxtamembrane (TM-JM) segment in bicelles: MD guided NMR refined structure. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2M20/Pdb  0.509
2013 Iversen L, Tu H, Lin W, Christensen S, Iwig J, Gureasko J, Kuriyan J, Groves JT. Functional Dynamics and Allosteric Regulation of Ras Activation by SOS Biophysical Journal. 104: 119a-120a. DOI: 10.1016/J.Bpj.2012.11.689  0.813
2013 Lin W, Iversen L, Tu H, Rhodes C, Christensen S, Iwig J, Kuriyan J, Groves JT. Clustering of Ras on Membrane Surfaces Independent of Lipid Anchor Effects Biophysical Journal. 104: 97a-98a. DOI: 10.1016/J.Bpj.2012.11.577  0.323
2012 Shan Y, Eastwood MP, Zhang X, Kim ET, Arkhipov A, Dror RO, Jumper J, Kuriyan J, Shaw DE. Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization. Cell. 149: 860-70. PMID 22579287 DOI: 10.1016/J.Cell.2012.02.063  0.627
2012 Kelch BA, Makino DL, O'Donnell M, Kuriyan J. Clamp loader ATPases and the evolution of DNA replication machinery Bmc Biology. 10. PMID 22520345 DOI: 10.1186/1741-7007-10-34  0.711
2012 Smith CC, Wang Q, Chin CS, Salerno S, Damon LE, Levis MJ, Perl AE, Travers KJ, Wang S, Hunt JP, Zarrinkar PP, Schadt EE, Kasarskis A, Kuriyan J, Shah NP. Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia Nature. 484: 260-263. PMID 22504184 DOI: 10.1038/Nature11016  0.434
2012 Henderson MN, Malecek KE, Makino DL, Cao XX, Shokat KM, Kuriyan J. Crystal Structure of the Kinase Domain of ABL in Complex with a Potent Rationally-Designed Derivative of the PP1 Inhibitor, AB129 Biophysical Journal. 102: 61a. DOI: 10.1016/J.Bpj.2011.11.363  0.482
2012 Tu H, Iversen L, Lin W, Christensen S, Iwig J, Gureasko J, Kuriyan J, Groves JT. Single Molecule Study of the Processive Ras/SOS Interaction Biophysical Journal. 102: 222a. DOI: 10.1016/J.Bpj.2011.11.1216  0.796
2012 Kelch B, Makino D, Simonetta K, O'Donnell M, Kuriyan J. Molecular mechanisms of DNA polymerase clamp loaders Nato Science For Peace and Security Series a: Chemistry and Biology. 103-114. DOI: 10.1007/978-94-007-2530-0_10  0.765
2011 Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp. Science (New York, N.Y.). 334: 1675-80. PMID 22194570 DOI: 10.1126/Science.1211884  0.719
2011 Winter MB, Herzik MA, Kuriyan J, Marletta MA. Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain. Proceedings of the National Academy of Sciences of the United States of America. 108: E881-9. PMID 21997213 DOI: 10.1073/Pnas.1114038108  0.55
2011 Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J. A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme. Cell. 146: 732-45. PMID 21884935 DOI: 10.1016/J.Cell.2011.07.038  0.827
2011 Endres NF, Engel K, Das R, Kovacs E, Kuriyan J. Regulation of the catalytic activity of the EGF receptor. Current Opinion in Structural Biology. 21: 777-84. PMID 21868214 DOI: 10.1016/J.Sbi.2011.07.007  0.819
2011 Jura N, Zhang X, Endres NF, Seeliger MA, Schindler T, Kuriyan J. Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms Molecular Cell. 42: 9-22. PMID 21474065 DOI: 10.1016/J.Molcel.2011.03.004  0.83
2011 Wickliffe KE, Lorenz S, Wemmer DE, Kuriyan J, Rape M. The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2. Cell. 144: 769-81. PMID 21376237 DOI: 10.1016/J.Cell.2011.01.035  0.554
2011 Smith CC, Chin J, Wang Q, Salerno S, Damon LE, Hunt JP, Levis MJ, Perl AE, Travers K, Wang S, Kasarskis A, Schadt E, Kuriyan J, Shah N. Validation of FLT3-ITD As a Therapeutic Target in Human Acute Myeloid Leukemia Blood. 118: 937-937. DOI: 10.1182/Blood.V118.21.937.937  0.461
2011 Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp Science. 334: 1675-1680. DOI: 10.1126/science.1211884  0.67
2011 Tu H, Iversen L, Lin W, Iwig J, Gureasko J, Kuriyan J, Groves J. The Residence Time and Processivity Study of the Ras/Sos Interaction Biophysical Journal. 100: 332a. DOI: 10.1016/J.Bpj.2010.12.2016  0.795
2011 Iversen L, Tu H, Lin W, Iwig J, Gureasko J, Kuriyan J, Groves JT. Single Molecule Processivity of SOS-cat, the Catalytic Core of the Ras Gef ‘son of Sevenless’ Biophysical Journal. 100: 256a. DOI: 10.1016/J.Bpj.2010.12.1615  0.792
2010 Olea C, Kuriyan J, Marletta MA. Modulating heme redox potential through protein-induced porphyrin distortion. Journal of the American Chemical Society. 132: 12794-5. PMID 20735135 DOI: 10.1021/Ja106252B  0.513
2010 Olea C, Herzik MA, Kuriyan J, Marletta MA. Structural insights into the molecular mechanism of H-NOX activation. Protein Science : a Publication of the Protein Society. 19: 881-7. PMID 20162612 DOI: 10.1002/Pro.357  0.578
2010 Chao LH, Pellicena P, Deindl S, Barclay LA, Schulman H, Kuriyan J. Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nature Structural & Molecular Biology. 17: 264-72. PMID 20139983 DOI: 10.1038/Nsmb.1751  0.82
2010 Gureasko J, Kuchment O, Makino DL, Sondermann H, Bar-Sagi D, Kuriyan J. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless Proceedings of the National Academy of Sciences of the United States of America. 107: 3430-3435. PMID 20133692 DOI: 10.1073/Pnas.0913915107  0.806
2010 McNally R, Bowman GD, Goedken ER, O'Donnell M, Kuriyan J. Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Structural Biology. 10: 3. PMID 20113510 DOI: 10.1186/1472-6807-10-3  0.783
2010 Gureasko J, Galush WJ, Sondermann H, Groves JT, Kuriyan J. Direct coupling of Ras to preformed maleimide-functionalized lipid membranes Nature Protocols. DOI: 10.1038/Nprot.2010.155  0.774
2009 Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J. Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3 Proceedings of the National Academy of Sciences of the United States of America. 106: 21608-21613. PMID 20007378 DOI: 10.1073/Pnas.0912101106  0.742
2009 Deindl S, Kadlecek TA, Cao X, Kuriyan J, Weiss A. Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response Proceedings of the National Academy of Sciences of the United States of America. 106: 20699-20704. PMID 19920178 DOI: 10.1073/Pnas.0911512106  0.82
2009 Levinson NM, Visperas PR, Kuriyan J. The tyrosine kinase Csk dimerizes through its SH3 domain Plos One. 4. PMID 19888460 DOI: 10.1371/Journal.Pone.0007683  0.832
2009 Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell. 137: 1293-307. PMID 19563760 DOI: 10.1016/J.Cell.2009.04.025  0.834
2009 Simonetta KR, Kazmirski SL, Goedken ER, Cantor AJ, Kelch BA, McNally R, Seyedin SN, Makino DL, O'Donnell M, Kuriyan J. The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell. 137: 659-71. PMID 19450514 DOI: 10.1016/J.Cell.2009.03.044  0.79
2009 Seeliger MA, Kuriyan J. A MAPK Scaffold Lends a Helping Hand Cell. 136: 994-996. PMID 19303841 DOI: 10.1016/J.Cell.2009.03.002  0.686
2009 Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, Kuriyan J, Weiss A. The structure, regulation, and function of ZAP-70 Immunological Reviews. 228: 41-57. PMID 19290920 DOI: 10.1111/J.1600-065X.2008.00753.X  0.793
2009 Seeliger MA, Ranjitkar P, Kasap C, Shan Y, Shaw DE, Shah NP, Kuriyan J, Maly DJ. Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations Cancer Research. 69: 2384-2392. PMID 19276351 DOI: 10.1158/0008-5472.Can-08-3953  0.724
2009 Muratore KE, Seeliger MA, Wang Z, Fomina D, Neiswinger J, Havranek JJ, Baker D, Kuriyan J, Cole PA. Comparative analysis of mutant tyrosine kinase chemical rescue. Biochemistry. 48: 3378-86. PMID 19260709 DOI: 10.1021/Bi900057G  0.735
2009 Winger JA, Hantschel O, Superti-Furga G, Kuriyan J. The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2) Bmc Structural Biology. 9. PMID 19236722 DOI: 10.1186/1472-6807-9-7  0.651
2009 Freedman TS, Sondermann H, Kuchment O, Friedland GD, Kortemme T, Kuriyan J. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1. Structure (London, England : 1993). 17: 41-53. PMID 19141281 DOI: 10.1016/J.Str.2008.11.004  0.807
2009 Shan Y, Seeliger MA, Eastwood MP, Frank F, Xu H, Jensen MØ, Dror RO, Kuriyan J, Shaw DE. A conserved protonation-dependent switch controls drug binding in the Abl kinase. Proceedings of the National Academy of Sciences of the United States of America. 106: 139-44. PMID 19109437 DOI: 10.1073/Pnas.0811223106  0.718
2009 Marletta MA, Derbyshire ER, Erbil WK, Fernhoff NB, Kuriyan J, Olea C, Price MS, Wemmer DE. A molecular view of the regulation of sGC activity Bmc Pharmacology. 9. DOI: 10.1186/1471-2210-9-S1-S27  0.617
2009 Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J. Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment (DOI:10.1016/j.cell.2009.04.025) Cell. 138: 604. DOI: 10.1016/J.Cell.2009.07.028  0.803
2008 Statsuk AV, Maly DJ, Seeliger MA, Fabian MA, Biggs WH, Lockhart DJ, Zarrinkar PP, Kuriyan J, Shokat KM. Tuning a three-component reaction for trapping kinase substrate complexes. Journal of the American Chemical Society. 130: 17568-74. PMID 19053485 DOI: 10.1021/Ja807066F  0.703
2008 Olea C, Boon EM, Pellicena P, Kuriyan J, Marletta MA. Probing the function of heme distortion in the H-NOX family. Acs Chemical Biology. 3: 703-10. PMID 19032091 DOI: 10.1021/Cb800185H  0.529
2008 Winger JA, Derbyshire ER, Lamers MH, Marletta MA, Kuriyan J. The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase. Bmc Structural Biology. 8: 42. PMID 18842118 DOI: 10.1186/1472-6807-8-42  0.818
2008 Azam M, Seeliger MA, Gray NS, Kuriyan J, Daley GQ. Activation of tyrosine kinases by mutation of the gatekeeper threonine Nature Structural and Molecular Biology. 15: 1109-1118. PMID 18794843 DOI: 10.1038/Nsmb.1486  0.723
2008 Georgescu RE, Yurieva O, Kim SS, Kuriyan J, Kong XP, O'Donnell M. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp Proceedings of the National Academy of Sciences of the United States of America. 105: 11116-11121. PMID 18678908 DOI: 10.1073/Pnas.0804754105  0.47
2008 Levinson NM, Seeliger MA, Cole PA, Kuriyan J. Structural Basis for the Recognition of c-Src by Its Inactivator Csk Cell. 134: 124-134. PMID 18614016 DOI: 10.1016/J.Cell.2008.05.051  0.801
2008 Gureasko J, Galush WJ, Boykevisch S, Sondermann H, Bar-Sagi D, Groves JT, Kuriyan J. Membrane-dependent signal integration by the Ras activator Son of sevenless. Nature Structural & Molecular Biology. 15: 452-61. PMID 18454158 DOI: 10.1038/Nsmb.1418  0.795
2008 Georgescu RE, Kim SS, Yurieva O, Kuriyan J, Kong XP, O'Donnell M. Structure of a Sliding Clamp on DNA Cell. 132: 43-54. PMID 18191219 DOI: 10.1016/J.Cell.2007.11.045  0.529
2008 Kasap C, Hertz N, Makino D, Shokat K, Kuriyan J, Shah NP. Beyond the Gatekeeper: Imatinib- and Dasatinib-Resistant BCR-ABL/F317 Mutations Confer Cross-Resistance to VX-680 but Are Sensitive to a Structural Derivative of VX-680 Blood. 112: 725-725. DOI: 10.1182/Blood.V112.11.725.725  0.387
2008 Gureasko J, Galush WJ, Boykevisch S, Sondermann H, Bar-Sagi D, Groves JT, Kuriyan J. Erratum: Membrane-dependent signal integration by the Ras activator Son of sevenless Nature Structural & Molecular Biology. 15: 651-651. DOI: 10.1038/nsmb0608-651a  0.789
2007 Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature. 450: 741-4. PMID 18046415 DOI: 10.1038/Nature05998  0.802
2007 Deindl S, Kadlecek TA, Brdicka T, Cao X, Weiss A, Kuriyan J. Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70 Cell. 129: 735-746. PMID 17512407 DOI: 10.1016/J.Cell.2007.03.039  0.835
2007 Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty Structure. 15: 299-311. PMID 17355866 DOI: 10.1016/J.Str.2007.01.015  0.78
2007 Azam M, Seeliger M, Gray NS, Kuriyan J, Daley GQ. A Unified Mechanism of Tyrosine Kinase Regulation by the Gatekeeper Residue. Blood. 110: 223-223. DOI: 10.1182/Blood.V110.11.223.223  0.735
2006 Boykevisch S, Zhao C, Sondermann H, Philippidou P, Halegoua S, Kuriyan J, Bar-Sagi D. Regulation of Ras Signaling Dynamics by Sos-Mediated Positive Feedback Current Biology. 16: 2173-2179. PMID 17084704 DOI: 10.1016/J.Cub.2006.09.033  0.802
2006 Pellicena P, Kuriyan J. Protein-protein interactions in the allosteric regulation of protein kinases Current Opinion in Structural Biology. 16: 702-709. PMID 17079130 DOI: 10.1016/J.Sbi.2006.10.007  0.472
2006 Freedman TS, Sondermann H, Friedland GD, Kortemme T, Bar-Sagi D, Marqusee S, Kuriyan J. A Ras-induced conformational switch in the Ras activator Son of sevenless. Proceedings of the National Academy of Sciences of the United States of America. 103: 16692-7. PMID 17075039 DOI: 10.1073/Pnas.0608127103  0.818
2006 Johnson A, Yao NY, Bowman GD, Kuriyan J, O'Donnell M. The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. The Journal of Biological Chemistry. 281: 35531-43. PMID 16980295 DOI: 10.1074/Jbc.M606090200  0.341
2006 Lamers MH, Georgescu RE, Lee SG, O'Donnell M, Kuriyan J. Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III Cell. 126: 881-892. PMID 16959568 DOI: 10.1016/J.Cell.2006.07.028  0.705
2006 Pirruccello M, Sondermann H, Pelton JG, Pellicena P, Hoelz A, Chernoff J, Wemmer DE, Kuriyan J. A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases. Journal of Molecular Biology. 361: 312-26. PMID 16837009 DOI: 10.1016/J.Jmb.2006.06.017  0.84
2006 Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Cell. 125: 1137-1149. PMID 16777603 DOI: 10.1016/J.Cell.2006.05.013  0.842
2006 Levinson NM, Kuchment O, Shen K, Young MA, Koldobskiy M, Karplus M, Cole PA, Kuriyan J. A Src-like inactive conformation in the abl tyrosine kinase domain. Plos Biology. 4: e144. PMID 16640460 DOI: 10.1371/Journal.Pbio.0040144  0.84
2006 Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J. Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase Molecular Cell. 21: 787-798. PMID 16543148 DOI: 10.1016/J.Molcel.2006.01.035  0.806
2006 Rosenberg OS, Deindl S, Comolli LR, Hoelz A, Downing KH, Nairn AC, Kuriyan J. Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II. The Febs Journal. 273: 682-94. PMID 16441656 DOI: 10.1111/J.1742-4658.2005.05088.X  0.829
2006 Young MA, Shah NP, Chao LH, Seeliger M, Milanov ZV, Biggs WH, Treiber DK, Patel HK, Zarrinkar PP, Lockhart DJ, Sawyers CL, Kuriyan J. Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680. Cancer Research. 66: 1007-14. PMID 16424036 DOI: 10.1158/0008-5472.Can-05-2788  0.838
2006 Argiriadi MA, Goedken ER, Bruck I, O'Donnell M, Kuriyan J. Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. Bmc Structural Biology. 6: 2. PMID 16403212 DOI: 10.1186/1472-6807-6-2  0.726
2006 O'Donnell M, Kuriyan J. Clamp loaders and replication initiation Current Opinion in Structural Biology. 16: 35-41. PMID 16377178 DOI: 10.1016/J.Sbi.2005.12.004  0.304
2006 Kim YS, Bhandari R, Cochran JR, Kuriyan J, Wittrup KD. Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast. Proteins. 62: 1026-35. PMID 16355407 DOI: 10.1002/Prot.20618  0.359
2005 Rosenberg OS, Deindl S, Sung RJ, Nairn AC, Kuriyan J. Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme. Cell. 123: 849-60. PMID 16325579 DOI: 10.1016/J.Cell.2005.10.029  0.779
2005 Sondermann H, Nagar B, Bar-Sagi D, Kuriyan J. Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless Proceedings of the National Academy of Sciences of the United States of America. 102: 16632-16637. PMID 16267129 DOI: 10.1073/Pnas.0508315102  0.821
2005 Seeliger MA, Young M, Henderson MN, Pellicena P, King DS, Falick AM, Kuriyan J. High yield bacterial expression of active c-Abl and c-Src tyrosine kinases Protein Science. 14: 3135-3139. PMID 16260764 DOI: 10.1110/Ps.051750905  0.721
2005 Kazmirski SL, Zhao Y, Bowman GD, O'Donnell M, Kuriyan J. Out-of-plane motions in open sliding clamps: Molecular dynamics simulations of eukaryotic and archaeal proliferating cell nuclear antigen Proceedings of the National Academy of Sciences of the United States of America. 102: 13801-13806. PMID 16169903 DOI: 10.1073/Pnas.0506430102  0.311
2005 Karplus M, Kuriyan J. Molecular dynamics and protein function. Proceedings of the National Academy of Sciences of the United States of America. 102: 6679-85. PMID 15870208 DOI: 10.1073/Pnas.0408930102  0.433
2005 Sondermann H, Kuriyan J. C2 can do it, too Cell. 121: 158-160. PMID 15851022 DOI: 10.1016/J.Cell.2005.04.001  0.803
2005 Nagar B, Kuriyan J. SAXS and the working protein Structure. 13: 169-173. PMID 15698559 DOI: 10.1016/J.Str.2005.01.001  0.585
2005 Bowman GD, Goedken ER, Kazmirski SL, O'Donnell M, Kuriyan J. DNA polymerase clamp loaders and DNA recognition. Febs Letters. 579: 863-7. PMID 15680964 DOI: 10.1016/J.Febslet.2004.11.038  0.708
2005 Goedken ER, Kazmirski SL, Bowman GD, O'Donnell M, Kuriyan J. Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex. Nature Structural & Molecular Biology. 12: 183-90. PMID 15665871 DOI: 10.1038/Nsmb889  0.718
2004 Kazmirski SL, Podobnik M, Weitze TF, O'Donnell M, Kuriyan J. Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex Proceedings of the National Academy of Sciences of the United States of America. 101: 16750-16755. PMID 15556993 DOI: 10.1073/Pnas.0407904101  0.39
2004 Sondermann H, Soisson SM, Boykevisch S, Yang SS, Bar-Sagi D, Kuriyan J. Structural analysis of autoinhibition in the Ras activator son of sevenless Cell. 119: 393-405. PMID 15507210 DOI: 10.1016/J.Cell.2004.10.005  0.808
2004 Pellicena P, Karow DS, Boon EM, Marletta MA, Kuriyan J. Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proceedings of the National Academy of Sciences of the United States of America. 101: 12854-9. PMID 15326296 DOI: 10.1073/Pnas.0405188101  0.597
2004 Bowman GD, O'Donnell M, Kuriyan J. Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex Nature. 429: 724-730. PMID 15201901 DOI: 10.1038/Nature02585  0.331
2004 Waksman G, Kuriyan J. Structure and specificity of the SH2 domain. Cell. 116: S45-48, 3 p followin. PMID 15055581 DOI: 10.1016/S0092-8674(04)00043-1  0.589
2004 Goedken ER, Levitus M, Johnson A, Bustamante C, O'Donnell M, Kuriyan J. Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. Journal of Molecular Biology. 336: 1047-59. PMID 15037068 DOI: 10.1016/J.Jmb.2003.12.074  0.748
2004 Gulbis JM, Kazmirski SL, Finkelstein J, Kelman Z, O'Donnell M, Kuriyan J. Crystal structure of the chi:psi subassembly of the Escherichia coli DNA polymerase clamp-loader complex European Journal of Biochemistry. 271: 439-449. PMID 14717711 DOI: 10.1046/J.1432-1033.2003.03944.X  0.381
2003 Sondermann H, Soisson SM, Bar-Sagi D, Kuriyan J. Tandem Histone Folds in the Structure of the N-Terminal Segment of the Ras Activator Son of Sevenless Structure. 11: 1583-1593. PMID 14656442 DOI: 10.1016/J.Str.2003.10.015  0.815
2003 Hoelz A, Nairn AC, Kuriyan J. Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II. Molecular Cell. 11: 1241-51. PMID 12769848 DOI: 10.1016/S1097-2765(03)00171-0  0.747
2003 Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell. 112: 859-871. PMID 12654251 DOI: 10.1016/S0092-8674(03)00194-6  0.69
2003 Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G. A myristoyl/phosphotyrosine switch regulates c-Abl Cell. 112: 845-857. PMID 12654250 DOI: 10.1016/S0092-8674(03)00191-0  0.685
2003 Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 112: 685-95. PMID 12628188 DOI: 10.1016/S0092-8674(03)00149-1  0.793
2003 Podobnik M, Weitze TF, O'Donnell M, Kuriyan J. Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit. Structure (London, England : 1993). 11: 253-63. PMID 12623013 DOI: 10.1016/S0969-2126(03)00027-3  0.366
2003 Chen X, Bhandari R, Vinkemeier U, Van Den Akker F, Darnell JE, Kuriyan J. A reinterpretation of the dimerization interface of the N-terminal domains of STATs. Protein Science : a Publication of the Protein Society. 12: 361-5. PMID 12538899 DOI: 10.1110/Ps.0218903  0.679
2003 Marletta M, Karow D, Pellicena P, Kuriyan J, Pan D, Mathies R. Characterization of heme protein sensors provides a basis for functional differences such as ligand recognition Bmc News and Views. 3. DOI: 10.1186/2048-4623-3-S2-Op020  0.489
2003 Young MA, Kuriyan J. Structures of Serine/Threonine and Tyrosine Kinases Handbook of Cell Signaling. 1: 387-390. DOI: 10.1016/B978-012124546-7/50429-0  0.303
2002 Davey MJ, Jeruzalmi D, Kuriyan J, O'Donnell M. Motors and switches: AAA+ machines within the replisome. Nature Reviews. Molecular Cell Biology. 3: 826-35. PMID 12415300 DOI: 10.1038/Nrm949  0.691
2002 Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, Sawyers CL. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2: 117-25. PMID 12204532 DOI: 10.1016/S1535-6108(02)00096-X  0.645
2002 Wisniewski D, Lambek CL, Liu C, Strife A, Veach DR, Nagar B, Young MA, Schindler T, Bornmann WG, Bertino JR, Kuriyan J, Clarkson B. Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases Cancer Research. 62: 4244-4255. PMID 12154026  0.582
2002 Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Research. 62: 4236-43. PMID 12154025 DOI: 10.2210/Pdb1Iep/Pdb  0.686
2002 Huse M, Kuriyan J. The conformational plasticity of protein kinases. Cell. 109: 275-82. PMID 12015977 DOI: 10.1016/S0092-8674(02)00741-9  0.754
2002 Jeruzalmi D, O'Donnell M, Kuriyan J. Clamp loaders and sliding clamps. Current Opinion in Structural Biology. 12: 217-24. PMID 11959500 DOI: 10.1016/S0959-440X(02)00313-5  0.693
2002 Bruck I, Yuzhakov A, Yurieva O, Jeruzalmi D, Skangalis M, Kuriyan J, O'Donnell M. Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile. The Journal of Biological Chemistry. 277: 17334-48. PMID 11859073 DOI: 10.1074/Jbc.M110198200  0.686
2002 Flavell RR, Huse M, Goger M, Trester-Zedlitz M, Kuriyan J, Muir TW. Efficient semisynthesis of a tetraphosphorylated analogue of the Type I TGFbeta receptor. Organic Letters. 4: 165-8. PMID 11796041 DOI: 10.1021/Ol016859I  0.724
2001 O'Donnell M, Jeruzalmi D, Kuriyan J. Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC. Current Biology : Cb. 11: R935-46. PMID 11719243 DOI: 10.1016/S0960-9822(01)00559-0  0.684
2001 Huse M, Muir TW, Xu L, Chen YG, Kuriyan J, Massagué J. The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Molecular Cell. 8: 671-82. PMID 11583628 DOI: 10.1016/S1097-2765(01)00332-X  0.74
2001 Jeruzalmi D, O'Donnell M, Kuriyan J. Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell. 106: 429-41. PMID 11525729 DOI: 10.1016/S0092-8674(01)00463-9  0.717
2001 Jeruzalmi D, Yurieva O, Zhao Y, Young M, Stewart J, Hingorani M, O'Donnell M, Kuriyan J. Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell. 106: 417-28. PMID 11525728 DOI: 10.1016/S0092-8674(01)00462-7  0.688
2001 Yamaguchi H, Matsushita M, Nairn AC, Kuriyan J. Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Molecular Cell. 7: 1047-57. PMID 11389851 DOI: 10.1016/S1097-2765(01)00256-8  0.45
2001 Hall BE, Yang SS, Boriack-Sjodin PA, Kuriyan J, Bar-Sagi D. Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange. The Journal of Biological Chemistry. 276: 27629-37. PMID 11333268 DOI: 10.1074/Jbc.M101727200  0.609
2001 Young MA, Gonfloni S, Superti-Furga G, Roux B, Kuriyan J. Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation. Cell. 105: 115-26. PMID 11301007 DOI: 10.1016/S0092-8674(01)00301-4  0.583
2000 Schindler T, Bornmann W, Pellicena P, Miller WT, Clarkson B, Kuriyan J. Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science (New York, N.Y.). 289: 1938-42. PMID 10988075 DOI: 10.1126/Science.289.5486.1938  0.488
2000 Podobnik M, McInerney P, O'Donnell M, Kuriyan J. A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases. Journal of Molecular Biology. 300: 353-62. PMID 10873470 DOI: 10.1006/Jmbi.2000.3844  0.368
2000 Jeruzalmi D, Kuriyan J, Doudna J. Paul Sigler (1934-2000). Trends in Biochemical Sciences. 25: 221-2. PMID 10782089 DOI: 10.1016/S0968-0004(00)01587-5  0.625
2000 Conti E, Kuriyan J. Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure (London, England : 1993). 8: 329-38. PMID 10745017 DOI: 10.1016/S0969-2126(00)00107-6  0.532
2000 Moarefi I, Jeruzalmi D, Turner J, O'Donnell M, Kuriyan J. Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage. Journal of Molecular Biology. 296: 1215-23. PMID 10698628 DOI: 10.1006/Jmbi.1999.3511  0.702
2000 Porter M, Schindler T, Kuriyan J, Miller WT. Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand. The Journal of Biological Chemistry. 275: 2721-6. PMID 10644735 DOI: 10.1074/jbc.275.4.2721  0.375
2000 Huse M, Holford MN, Kuriyan J, Muir TW. Semisynthesis of hyperphosphorylated type I TGFβ receptor: Addressing the mechanism of kinase activation [20] Journal of the American Chemical Society. 122: 8337-8338. DOI: 10.1021/Ja001763P  0.761
1999 Sali A, Kuriyan J. Challenges at the frontiers of structural biology. Trends in Cell Biology. 9: M20-4. PMID 10611675 DOI: 10.1016/S0968-0004(99)01494-2  0.494
1999 Zhao Y, Jeruzalmi D, Moarefi I, Leighton L, Lasken R, Kuriyan J. Crystal structure of an archaebacterial DNA polymerase. Structure (London, England : 1993). 7: 1189-99. PMID 10545321 DOI: 10.1016/S0969-2126(00)80053-2  0.715
1999 Schindler T, Sicheri F, Pico A, Gazit A, Levitzki A, Kuriyan J. Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor Molecular Cell. 3: 639-648. PMID 10360180 DOI: 10.1016/S1097-2765(00)80357-3  0.781
1999 Kuriyan J, Darnell JE. An SH2 domain in disguise. Nature. 398: 22-3, 25. PMID 10078523 DOI: 10.1038/17916  0.555
1999 Huse M, Chen YG, Massagué J, Kuriyan J. Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell. 96: 425-36. PMID 10025408 DOI: 10.1016/S0092-8674(00)80555-3  0.749
1999 Lafevre-Bernt M, Sicheri F, Pico A, Porter M, Kuriyan J, Todd Miller W. Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue Journal of Biological Chemistry. 273: 32129-32134. PMID 9822689 DOI: 10.1074/Jbc.273.48.32129  0.786
1998 Soisson SM, Nimnual AS, Uy M, Bar-Sagi D, Kuriyan J. Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein. Cell. 95: 259-68. PMID 9790532 DOI: 10.1016/S0092-8674(00)81756-0  0.632
1998 Conti E, Uy M, Leighton L, Blobel G, Kuriyan J. Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell. 94: 193-204. PMID 9695948 DOI: 10.1016/S0092-8674(00)81419-1  0.522
1998 Boriack-Sjodin PA, Margarit SM, Bar-Sagi D, Kuriyan J. The structural basis of the activation of Ras by Sos. Nature. 394: 337-43. PMID 9690470 DOI: 10.1038/28548  0.6
1998 Lee CH, Cowburn D, Kuriyan J. Peptide recognition mechanisms of eukaryotic signaling modules. Methods in Molecular Biology (Clifton, N.J.). 84: 3-31. PMID 9666439 DOI: 10.1385/0-89603-488-7:3  0.517
1998 Chen X, Vinkemeier U, Zhao Y, Jeruzalmi D, Darnell JE, Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell. 93: 827-39. PMID 9630226 DOI: 10.1016/S0092-8674(00)81443-9  0.82
1998 Vinkemeier U, Moarefi I, Darnell JE, Kuriyan J. Structure of the amino-terminal protein interaction domain of STAT-4. Science (New York, N.Y.). 279: 1048-52. PMID 9461439 DOI: 10.1126/Science.279.5353.1048  0.599
1997 Sicheri F, Kuriyan J. Structures of Src-family tyrosine kinases Current Opinion in Structural Biology. 7: 777-785. PMID 9434895 DOI: 10.1016/S0959-440X(97)80146-7  0.678
1997 Guenther B, Onrust R, Sali A, O'Donnell M, Kuriyan J. Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. Cell. 91: 335-45. PMID 9363942 DOI: 10.1016/S0092-8674(00)80417-1  0.559
1997 Yurieva O, Skangalis M, Kuriyan J, O'Donnell M. Thermus thermophilis dnaX homolog encoding gamma- and tau-like proteins of the chromosomal replicase. The Journal of Biological Chemistry. 272: 27131-9. PMID 9341154 DOI: 10.1074/Jbc.272.43.27131  0.308
1997 Zhang Z, Lee CH, Mandiyan V, Borg JP, Margolis B, Schlessinger J, Kuriyan J. Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. The Embo Journal. 16: 6141-50. PMID 9321393 DOI: 10.1093/Emboj/16.20.6141  0.4
1997 Kuriyan J, Cowburn D. Modular peptide recognition domains in eukaryotic signaling Annual Review of Biophysics and Biomolecular Structure. 26: 259-288. PMID 9241420 DOI: 10.1146/Annurev.Biophys.26.1.259  0.597
1997 Harrison CJ, Hayer-Hartl M, Di Liberto M, Hartl F, Kuriyan J. Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK. Science (New York, N.Y.). 276: 431-5. PMID 9103205 DOI: 10.1126/Science.276.5311.431  0.403
1997 Moarefi I, LaFevre-Bernt M, Sicheri F, Huse M, Lee CH, Kuriyan J, Miller WT. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement Nature. 385: 650-653. PMID 9024665 DOI: 10.1038/385650A0  0.817
1997 Sicheri F, Moarefi I, Kuriyan J. Crystal structure of the Src family tyrosine kinase Hck Nature. 385: 602-609. PMID 9024658 DOI: 10.1038/385602A0  0.693
1997 Kuriyan J, Moarefi L, Sicheri F, Lee CH, Huse M. Structure and regulation of sre-family tyrosine kinases Faseb Journal. 11: A875.  0.578
1996 Vinkemeier U, Cohen SL, Moarefi I, Chait BT, Kuriyan J, Darnell JE. DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. The Embo Journal. 15: 5616-26. PMID 8896455 DOI: 10.1002/J.1460-2075.1996.Tb00946.X  0.561
1996 Gulbis JM, Kelman Z, Hurwitz J, O'Donnell M, Kuriyan J. Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA Cell. 87: 297-306. PMID 8861913 DOI: 10.1016/S0092-8674(00)81347-1  0.34
1996 Chi-Hon L, Saksela K, Mirza UA, Chait BT, Kuriyan J. Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain Cell. 85: 931-942. PMID 8681387 DOI: 10.1016/S0092-8674(00)81276-3  0.426
1996 Goldberg J, Nairn AC, Kuriyan J. Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell. 84: 875-87. PMID 8601311 DOI: 10.1016/S0092-8674(00)81066-1  0.474
1995 Wu X, Knudsen B, Feller SM, Zheng J, Sali A, Cowburn D, Hanafusa H, Kuriyan J. Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure (London, England : 1993). 3: 215-26. PMID 7735837 DOI: 10.1016/S0969-2126(01)00151-4  0.676
1995 Kuriyan J, Thanos D. Structure of the NF-κB transcription factor: a holistic interaction with DNA Structure. 3: 135-141. PMID 7735829 DOI: 10.1016/S0969-2126(01)00143-5  0.319
1995 Wilson DS, Guenther B, Desplan C, Kuriyan J. High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. Cell. 82: 709-19. PMID 7671301 DOI: 10.1016/0092-8674(95)90468-9  0.338
1995 Goldberg J, Huang HB, Kwon YG, Greengard P, Nairn AC, Kuriyan J. Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature. 376: 745-53. PMID 7651533 DOI: 10.1038/376745A0  0.382
1995 Lee CH, Leung B, Lemmon MA, Zheng J, Cowburn D, Kuriyan J, Saksela K. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein Embo Journal. 14: 5006-5015. PMID 7588629  0.538
1995 Lee C, Leung B, Lemmon MA, Zheng J, Cowburn D, Kuriyan J, Saksela K. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein The Embo Journal. 14: 5006-5015. DOI: 10.1002/J.1460-2075.1995.Tb00183.X  0.587
1994 Waksman G, Krishna TSR, Williams CH, Kuriyan J. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 Å resolution: Implications for a large conformational change during catalysis Journal of Molecular Biology. 236: 800-816. PMID 8114095 DOI: 10.2210/Pdb1Tde/Pdb  0.58
1994 Krishna TSR, Kong XP, Gary S, Burgers PM, Kuriyan J. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA Cell. 79: 1233-1243. PMID 8001157 DOI: 10.1016/0092-8674(94)90014-0  0.544
1994 Krishna TSR, Fenyö D, Kong XP, Gary S, Chait BT, Burgers P, Kuriyan J. Crystallization of proliferating cell nuclear antigen (PCNA) from saccharomyces cerevisiae Journal of Molecular Biology. 241: 265-268. PMID 7914545 DOI: 10.1006/Jmbi.1994.1495  0.521
1994 Lee CH, Kominos D, Jacques S, Margolis B, Schlessinger J, Shoelson SE, Kuriyan J. Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure (London, England : 1993). 2: 423-38. PMID 7521735 DOI: 10.1016/S0969-2126(00)00044-7  0.456
1994 Waksman G, Krishna TSR, Williams CH, Kuriyan J. Crystal Structure of Escherichia coli Thioredoxin Reductase Refined at 2 Å Resolution Journal of Molecular Biology. 236: 800-816. DOI: 10.1006/Jmbi.1994.1190  0.509
1993 Martin JL, Waksman G, Bardwell JCA, Beckwith J, Kuriyan J. Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo Journal of Molecular Biology. 230: 1097-1100. PMID 8478925 DOI: 10.1006/Jmbi.1993.1226  0.513
1993 Martin JL, Bardwell JCA, Kuriyan J. Crystal structure of the DsbA protein required for disulphide bond formation in vivo Nature. 365: 464-468. PMID 8413591 DOI: 10.1038/365464A0  0.366
1993 Kuriyan J, O'Donnell M. Sliding clamps of DNA polymerases Journal of Molecular Biology. 234: 915-925. PMID 7903401 DOI: 10.1006/Jmbi.1993.1644  0.317
1993 Waksman G, Shoelson SE, Pant N, Cowburn D, Kuriyan J. Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell. 72: 779-90. PMID 7680960 DOI: 10.1016/0092-8674(93)90405-F  0.706
1993 Kuriyan J, Cowburn D. Structures of SH2 and SH3 domains. Current opinion in structural biology 1993, 3:828-837 Current Opinion in Structural Biology. 3: 828-837. DOI: 10.1016/0959-440X(93)90145-B  0.648
1992 Waksman G, Kominos D, Robertson SC, Pant N, Baltimore D, Birge RB, Cowburn D, Hanafusa H, Mayer BJ, Overduin M, Resh MD, Rios CB, Silverman L, Kuriyan J. Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides Nature. 358: 646-653. PMID 1379696 DOI: 10.1038/358646A0  0.698
1992 O'Donnell M, Kuriyan J, Kong XP, Stukenberg PT, Onrust R. The sliding clamp of DNA polymerase III holoenzyme encircles DNA Molecular Biology of the Cell. 3: 953-957. PMID 1358275 DOI: 10.1091/Mbc.3.9.953  0.483
1992 Kong XP, Onrust R, O'Donnell M, Kuriyan J. Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp Cell. 69: 425-437. PMID 1349852 DOI: 10.1016/0092-8674(92)90445-I  0.549
1992 Kuriyan J, Burley SK. DNA recognition, warts and all Nature. 359: 476. DOI: 10.1038/359476A0  0.477
1991 Kuriyan J, Krishna TSR, Wong L, Guenther B, Pahler A, Williams CH, Model P. Convergent evolution of similar function in two structurally divergent enzymes Nature. 352: 172-174. PMID 2067578 DOI: 10.1038/352172A0  0.41
1991 Kuriyan J, Osapay K, Burley SK, Brünger AT, Hendrickson WA, Karplus M. Exploration of disorder in protein structures by X-ray restrained molecular dynamics. Proteins. 10: 340-58. PMID 1946343 DOI: 10.1002/Prot.340100407  0.567
1991 Henderson GB, Murgolo NJ, Kuriyan J, Osapay K, Kominos D, Berry A, Scrutton NS, Hinchliffe NW, Perham RN, Cerami A. Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction. Proceedings of the National Academy of Sciences of the United States of America. 88: 8769-73. PMID 1924337 DOI: 10.1073/Pnas.88.19.8769  0.304
1991 Kuriyan J, Kong XP, Krishna TSR, Sweet RM, Murgolo NJ, Field H, Cerami A, Henderson GB. X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-Å resolution Proceedings of the National Academy of Sciences of the United States of America. 88: 8764-8768. PMID 1924336 DOI: 10.1073/Pnas.88.19.8764  0.532
1990 Kuczera K, Kuriyan J, Karplus M. Temperature dependence of the structure and dynamics of myoglobin. A simulation approach. Journal of Molecular Biology. 213: 351-73. PMID 2342112 DOI: 10.1016/S0022-2836(05)80196-2  0.4
1989 Kuriyan J, Brünger AT, Karplus M, Hendrickson WA. X-ray refinement of protein structures by simulated annealing: test of the method on myohemerythrin. Acta Crystallographica. Section a, Foundations of Crystallography. 45: 396-409. PMID 2619971 DOI: 10.1107/S0108767389000437  0.348
1987 Brünger AT, Kuriyan J, Karplus M. Crystallographic R factor refinement by molecular dynamics. Science (New York, N.Y.). 235: 458-60. PMID 17810339 DOI: 10.1126/Science.235.4787.458  0.591
1987 Frauenfelder H, Hartmann H, Karplus M, Kuntz ID, Kuriyan J, Parak F, Petsko GA, Ringe D, Tilton RF, Connolly ML. Thermal expansion of a protein. Biochemistry. 26: 254-61. PMID 3828301 DOI: 10.1021/Bi00375A035  0.54
1987 Karplus M, Brünger AT, Elber R, Kuriyan J. Molecular dynamics: applications to proteins. Cold Spring Harbor Symposia On Quantitative Biology. 52: 381-90. PMID 3454267 DOI: 10.1101/Sqb.1987.052.01.044  0.598
1987 Kuriyan J, Karplus M, Petsko GA. Estimation of uncertainties in X-ray refinement results by use of perturbed structures. Proteins. 2: 1-12. PMID 3447165 DOI: 10.1002/Prot.340020102  0.525
1986 Kuriyan J, Wilz S, Karplus M, Petsko GA. X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution. Journal of Molecular Biology. 192: 133-54. PMID 3820301 DOI: 10.1016/0022-2836(86)90470-5  0.555
1986 Kuriyan J, Petsko GA, Levy RM, Karplus M. Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics. Journal of Molecular Biology. 190: 227-54. PMID 3795269 DOI: 10.1016/0022-2836(86)90295-0  0.63
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