Joseph Schlessinger - Publications

Affiliations: 
Pharmacology Yale University, New Haven, CT 
Area:
tyrosine phosphorylation
Website:
http://bbs.yale.edu/people/joseph_schlessinger.profile

327 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kuzina ES, Ung PM, Mohanty J, Tome F, Choi J, Pardon E, Steyaert J, Lax I, Schlessinger A, Schlessinger J, Lee S. Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30944224 DOI: 10.1073/pnas.1822055116  0.44
2018 Axelrod D, Elson EL, Schlessinger J, Koppel DE. Reminiscences on the "Classic" 1976 FRAP Article in Biophysical Journal. Biophysical Journal. PMID 30224052 DOI: 10.1016/j.bpj.2018.08.037  0.72
2018 Reshetnyak AV, Mohanty J, Tomé F, Puleo DE, Plotnikov AN, Ahmed M, Kaur N, Poliakov A, Cinnaiyan AM, Lax I, Schlessinger J. Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α). Proceedings of the National Academy of Sciences of the United States of America. PMID 30061385 DOI: 10.1073/pnas.1807881115  0.52
2018 Lee S, Choi J, Mohanty J, Sousa LP, Tome F, Pardon E, Steyaert J, Lemmon MA, Lax I, Schlessinger J. Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature. PMID 29342135 DOI: 10.1038/nature25010  0.96
2017 Puleo DE, Kucera K, Hammarén HM, Ungureanu D, Newton AS, Silvennoinen O, Jorgensen WL, Schlessinger J. Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders. Acs Medicinal Chemistry Letters. 8: 618-621. PMID 28626521 DOI: 10.1021/acsmedchemlett.7b00153  0.32
2016 Shi X, Sousa LP, Mandel-Bausch EM, Tome F, Reshetnyak AV, Hadari Y, Schlessinger J, Lax I. Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482095 DOI: 10.1073/pnas.1610179113  0.44
2016 Lemmon MA, Freed DM, Schlessinger J, Kiyatkin A. The Dark Side of Cell Signaling: Positive Roles for Negative Regulators. Cell. 164: 1172-1184. PMID 26967284 DOI: 10.1016/j.cell.2016.02.047  0.96
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Schlessinger J, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/ncomms10882  0.4
2016 Zhao ZM, Zhao B, Bai Y, Iamarino A, Gaffney SG, Schlessinger J, Lifton RP, Rimm DL, Townsend JP. Early and multiple origins of metastatic lineages within primary tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858460 DOI: 10.1073/pnas.1525677113  1
2015 Reshetnyak AV, Murray PB, Shi X, Mo ES, Mohanty J, Tome F, Bai H, Gunel M, Lax I, Schlessinger J. Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 26630010 DOI: 10.1073/pnas.1520099112  1
2015 Lee S, Greenlee EB, Amick JR, Ligon GF, Lillquist JS, Natoli EJ, Hadari Y, Alvarado D, Schlessinger J. Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460020 DOI: 10.1073/pnas.1518361112  1
2015 Perry RJ, Lee S, Ma L, Zhang D, Schlessinger J, Shulman GI. FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nature Communications. 6: 6980. PMID 25916467 DOI: 10.1038/ncomms7980  1
2015 Murray PB, Lax I, Reshetnyak A, Ligon GF, Lillquist JS, Natoli EJ, Shi X, Folta-Stogniew E, Gunel M, Alvarado D, Schlessinger J. Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK. Science Signaling. 8: ra6. PMID 25605972 DOI: 10.1126/scisignal.2005916  1
2015 Reshetnyak AV, Opatowsky Y, Boggon TJ, Folta-Stogniew E, Tome F, Lax I, Schlessinger J. The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer. Molecular Cell. 57: 191-201. PMID 25544564 DOI: 10.1016/j.molcel.2014.11.021  1
2015 Juhlin CC, Goh G, Healy JM, Fonseca AL, Scholl UI, Stenman A, Kunstman JW, Brown TC, Overton JD, Mane SM, Nelson-Williams C, Bäckdahl M, Suttorp AC, Haase M, Choi M, ... Schlessinger J, et al. Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma. The Journal of Clinical Endocrinology and Metabolism. 100: E493-502. PMID 25490274 DOI: 10.1210/jc.2014-3282  1
2015 Krauthammer M, Kong Y, Bacchiocchi A, Evans P, Pornputtapong N, Wu C, McCusker JP, Ma S, Cheng E, Straub R, Serin M, Bosenberg M, Ariyan S, Narayan D, Sznol M, ... ... Schlessinger J, et al. Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas Nature Genetics. DOI: 10.1038/ng.3361  1
2014 Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G. Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. Elife. 3. PMID 25265470 DOI: 10.7554/eLife.03385  0.44
2014 Chen PY, Qin L, Zhuang ZW, Tellides G, Lax I, Schlessinger J, Simons M. The docking protein FRS2α is a critical regulator of VEGF receptors signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 5514-9. PMID 24706887 DOI: 10.1073/pnas.1404545111  1
2014 Lemmon MA, Schlessinger J, Ferguson KM. The EGFR family: not so prototypical receptor tyrosine kinases. Cold Spring Harbor Perspectives in Biology. 6: a020768. PMID 24691965 DOI: 10.1101/cshperspect.a020768  1
2014 Schlessinger J. Receptor tyrosine kinases: legacy of the first two decades. Cold Spring Harbor Perspectives in Biology. 6. PMID 24591517 DOI: 10.1101/cshperspect.a008912  1
2014 Opatowsky Y, Lax I, Tomé F, Bleichert F, Unger VM, Schlessinger J. Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers. Proceedings of the National Academy of Sciences of the United States of America. 111: 1772-7. PMID 24449920 DOI: 10.1073/pnas.1323254111  1
2013 Schlessinger J. Tony Pawson (1952-2013). Cancer Cell. 24: 273-4. PMID 24159606  1
2013 Reshetnyak AV, Nelson B, Shi X, Boggon TJ, Pavlenco A, Mandel-Bausch EM, Tome F, Suzuki Y, Sidhu SS, Lax I, Schlessinger J. Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proceedings of the National Academy of Sciences of the United States of America. 110: 17832-7. PMID 24127596 DOI: 10.1073/pnas.1317118110  1
2013 Zhao S, Choi M, Overton JD, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N, Hui P, Abu-Khalaf M, Ravaggi A, ... ... Schlessinger J, et al. Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 2916-21. PMID 23359684 DOI: 10.1073/pnas.1222577110  1
2013 Davis MJ, Ha BH, Holman EC, Halaban R, Schlessinger J, Boggon TJ. RAC1P29S is a spontaneously activating cancer-associated GTPase. Proceedings of the National Academy of Sciences of the United States of America. 110: 912-7. PMID 23284172 DOI: 10.1073/pnas.1220895110  1
2013 Goldberg SB, Schlessinger J, Boyer JL, Herbst RS. A step towards treating KRAS-mutant NSCLC. The Lancet. Oncology. 14: 3-5. PMID 23200176 DOI: 10.1016/S1470-2045(12)70528-4  1
2012 Davis MJ, Schlessinger J. The genesis of Zelboraf: targeting mutant B-Raf in melanoma. The Journal of Cell Biology. 199: 15-9. PMID 23027900 DOI: 10.1083/jcb.201205167  1
2012 Ha BH, Davis MJ, Chen C, Lou HJ, Gao J, Zhang R, Krauthammer M, Halaban R, Schlessinger J, Turk BE, Boggon TJ. Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proceedings of the National Academy of Sciences of the United States of America. 109: 16107-12. PMID 22988085 DOI: 10.1073/pnas.1214447109  1
2012 Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, ... ... Schlessinger J, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nature Genetics. 44: 1006-14. PMID 22842228 DOI: 10.1038/ng.2359  1
2012 Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J. Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America. 109: 4419-24. PMID 22371560 DOI: 10.1073/pnas.1200164109  1
2011 Ekkati AR, Madiyan V, Ravindranathan KP, H Bae J, Schlessinger J, Jorgensen WL. Aryl Extensions of Thienopyrimidinones as Fibroblast Growth Factor Receptor 1 Kinase Inhibitors. Tetrahedron Letters. 52: 2228-2231. PMID 21516197 DOI: 10.1016/j.tetlet.2010.12.081  1
2011 Kamen LA, Schlessinger J, Lowell CA. Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 186: 1656-65. PMID 21187437 DOI: 10.4049/jimmunol.1002093  1
2011 Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P. Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Molecular Biology of the Cell. 22: 493-502. PMID 21169560 DOI: 10.1091/mbc.E10-07-0637  1
2010 Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, ... ... Schlessinger J, et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature. 467: 596-9. PMID 20823850 DOI: 10.1038/nature09454  1
2010 Beinke S, Phee H, Clingan JM, Schlessinger J, Matloubian M, Weiss A. Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate. Proceedings of the National Academy of Sciences of the United States of America. 107: 16234-9. PMID 20805505 DOI: 10.1073/pnas.1011556107  1
2010 Sato T, Shimazaki T, Naka H, Fukami S, Satoh Y, Okano H, Lax I, Schlessinger J, Gotoh N. FRS2α regulates Erk levels to control a self-renewal target Hes1 and proliferation of FGF-responsive neural stem/progenitor cells. Stem Cells (Dayton, Ohio). 28: 1661-73. PMID 20652960 DOI: 10.1002/stem.488  1
2010 Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 141: 1117-34. PMID 20602996 DOI: 10.1016/j.cell.2010.06.011  1
2010 Bae JH, Schlessinger J. Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases. Molecules and Cells. 29: 443-8. PMID 20432069 DOI: 10.1007/s10059-010-0080-5  1
2010 Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 464: 783-7. PMID 20208517 DOI: 10.1038/nature08827  1
2010 Bae JH, Boggon TJ, Tomé F, Mandiyan V, Lax I, Schlessinger J. Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 2866-71. PMID 20133753 DOI: 10.1073/pnas.0914157107  1
2010 Ravindranathan KP, Mandiyan V, Ekkati AR, Bae JH, Schlessinger J, Jorgensen WL. Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening. Journal of Medicinal Chemistry. 53: 1662-72. PMID 20121196 DOI: 10.1021/jm901386e  1
2010 Yang Y, Xie P, Opatowsky Y, Schlessinger J. Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 1906-11. PMID 20080685 DOI: 10.1073/pnas.0914052107  1
2010 Murohashi M, Nakamura T, Tanaka S, Ichise T, Yoshida N, Yamamoto T, Shibuya M, Schlessinger J, Gotoh N. An FGF4-FRS2alpha-Cdx2 axis in trophoblast stem cells induces Bmp4 to regulate proper growth of early mouse embryos. Stem Cells (Dayton, Ohio). 28: 113-21. PMID 19890878 DOI: 10.1002/stem.247  1
2009 Bae JH, Lew ED, Yuzawa S, Tomé F, Lax I, Schlessinger J. The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site. Cell. 138: 514-24. PMID 19665973 DOI: 10.1016/j.cell.2009.05.028  1
2009 Margulies D, Opatowsky Y, Fletcher S, Saraogi I, Tsou LK, Saha S, Lax I, Schlessinger J, Hamilton AD. Surface binding inhibitors of the SCF-KIT protein-protein interaction. Chembiochem : a European Journal of Chemical Biology. 10: 1955-8. PMID 19637142 DOI: 10.1002/cbic.200900079  0.36
2009 Hadari Y, Schlessinger J. FGFR3-targeted mAb therapy for bladder cancer and multiple myeloma. The Journal of Clinical Investigation. 119: 1077-9. PMID 19422094 DOI: 10.1172/JCI38948  1
2009 Lulo J, Yuzawa S, Schlessinger J. Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2. Biochemical and Biophysical Research Communications. 383: 347-52. PMID 19358827 DOI: 10.1016/j.bbrc.2009.04.011  1
2009 Lew ED, Furdui CM, Anderson KS, Schlessinger J. The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations. Science Signaling. 2: ra6. PMID 19224897 DOI: 10.1126/scisignal.2000021  1
2009 Schlessinger J, VanHook AM. Science Signaling podcast: 03 march 2009 Science Signaling. 2: pc5. DOI: 10.1126/scisignal.260pc5  1
2008 Yang Y, Yuzawa S, Schlessinger J. Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization. Proceedings of the National Academy of Sciences of the United States of America. 105: 7681-6. PMID 18505839 DOI: 10.1073/pnas.0802896105  1
2008 Yuzawa S, Schlessinger J. [Structural biology of receptor tyrosine kinase kit]. Seikagaku. the Journal of Japanese Biochemical Society. 80: 94-104. PMID 18341028  1
2008 Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, ... ... Schlessinger J, et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proceedings of the National Academy of Sciences of the United States of America. 105: 3041-6. PMID 18287029 DOI: 10.1073/pnas.0711741105  1
2008 Wang L, Tassiulas I, Park-Min KH, Reid AC, Gil-Henn H, Schlessinger J, Baron R, Zhang JJ, Ivashkiv LB. 'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages. Nature Immunology. 9: 186-93. PMID 18084294 DOI: 10.1038/ni1548  1
2008 Yarden Y, Schlessinger J. The EGF receptor kinase: Evidence for allosteric activation and intramolecular self-phosphorylation Growth Factors in Biology and Medicine. 23-45. DOI: 10.1002/9780470720974.ch3  1
2007 Lew ED, Bae JH, Rohmann E, Wollnik B, Schlessinger J. Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 19802-7. PMID 18056630 DOI: 10.1073/pnas.0709905104  1
2007 Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, Neff L, Sanjay A, Bruzzaniti A, De Camilli P, Baron R, Schlessinger J. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. The Journal of Cell Biology. 178: 1053-64. PMID 17846174 DOI: 10.1083/jcb.200701148  1
2007 Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I. Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway. Molecular and Cellular Biology. 27: 6903-12. PMID 17682060 DOI: 10.1128/MCB.00544-07  1
2007 Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 130: 323-34. PMID 17662946 DOI: 10.1016/j.cell.2007.05.055  1
2007 Eswarakumar VP, Schlessinger J. Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 104: 3937-42. PMID 17360456 DOI: 10.1073/pnas.0700012104  1
2006 Eswarakumar VP, Ozcan F, Lew ED, Bae JH, Tomé F, Booth CJ, Adams DJ, Lax I, Schlessinger J. Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 18603-8. PMID 17132737 DOI: 10.1073/pnas.0609157103  1
2006 Schlessinger J, Lemmon MA. Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell. 127: 45-8. PMID 17018275 DOI: 10.1016/j.cell.2006.09.013  1
2006 Lamprianou S, Vacaresse N, Suzuki Y, Meziane H, Buxbaum JD, Schlessinger J, Harroch S. Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development. Molecular and Cellular Biology. 26: 5106-19. PMID 16782895 DOI: 10.1128/MCB.00101-06  1
2006 Galisteo ML, Yang Y, Ureña J, Schlessinger J. Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. Proceedings of the National Academy of Sciences of the United States of America. 103: 9796-801. PMID 16777958 DOI: 10.1073/pnas.0603714103  1
2006 Ozcan F, Klein P, Lemmon MA, Lax I, Schlessinger J. On the nature of low- and high-affinity EGF receptors on living cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 5735-40. PMID 16571657 DOI: 10.1073/pnas.0601469103  1
2006 Furdui CM, Lew ED, Schlessinger J, Anderson KS. Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction. Molecular Cell. 21: 711-7. PMID 16507368 DOI: 10.1016/j.molcel.2006.01.022  1
2006 Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nürnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, ... ... Schlessinger J, et al. Mutations in different components of FGF signaling in LADD syndrome. Nature Genetics. 38: 414-7. PMID 16501574 DOI: 10.1038/ng1757  1
2005 Yokote H, Fujita K, Jing X, Sawada T, Liang S, Yao L, Yan X, Zhang Y, Schlessinger J, Sakaguchi K. Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains. Proceedings of the National Academy of Sciences of the United States of America. 102: 18866-71. PMID 16365308 DOI: 10.1073/pnas.0509741102  1
2005 Yamamoto S, Yoshino I, Shimazaki T, Murohashi M, Hevner RF, Lax I, Okano H, Shibuya M, Schlessinger J, Gotoh N. Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 15983-8. PMID 16239343 DOI: 10.1073/pnas.0507961102  1
2005 Dawson JP, Berger MB, Lin CC, Schlessinger J, Lemmon MA, Ferguson KM. Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface. Molecular and Cellular Biology. 25: 7734-42. PMID 16107719 DOI: 10.1128/MCB.25.17.7734-7742.2005  1
2005 Gotoh N, Manova K, Tanaka S, Murohashi M, Hadari Y, Lee A, Hamada Y, Hiroe T, Ito M, Kurihara T, Nakazato H, Shibuya M, Lax I, Lacy E, Schlessinger J. The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development. Molecular and Cellular Biology. 25: 4105-16. PMID 15870281 DOI: 10.1128/MCB.25.10.4105-4116.2005  1
2005 Eswarakumar VP, Lax I, Schlessinger J. Cellular signaling by fibroblast growth factor receptors. Cytokine & Growth Factor Reviews. 16: 139-49. PMID 15863030 DOI: 10.1016/j.cytogfr.2005.01.001  1
2005 Card GL, Blasdel L, England BP, Zhang C, Suzuki Y, Gillette S, Fong D, Ibrahim PN, Artis DR, Bollag G, Milburn MV, Kim SH, Schlessinger J, Zhang KY. A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design. Nature Biotechnology. 23: 201-7. PMID 15685167 DOI: 10.1038/nbt1059  1
2005 Schlessinger J. SU11248: Genesis of a new cancer drug: The development of a promising RTK inhibitor. Scientist. 19: 17-18.  1
2004 Card GL, England BP, Suzuki Y, Fong D, Powell B, Lee B, Luu C, Tabrizizad M, Gillette S, Ibrahim PN, Artis DR, Bollag G, Milburn MV, Kim SH, Schlessinger J, et al. Structural basis for the activity of drugs that inhibit phosphodiesterases. Structure (London, England : 1993). 12: 2233-47. PMID 15576036 DOI: 10.1016/j.str.2004.10.004  1
2004 Gotoh N, Ito M, Yamamoto S, Yoshino I, Song N, Wang Y, Lax I, Schlessinger J, Shibuya M, Lang RA. Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. Proceedings of the National Academy of Sciences of the United States of America. 101: 17144-9. PMID 15569927 DOI: 10.1073/pnas.0407577101  1
2004 Schlessinger J. Common and distinct elements in cellular signaling via EGF and FGF receptors. Science (New York, N.Y.). 306: 1506-7. PMID 15567848 DOI: 10.1126/science.1105396  1
2004 Mattoon DR, Lamothe B, Lax I, Schlessinger J. The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway. Bmc Biology. 2: 24. PMID 15550174 DOI: 10.1186/1741-7007-2-24  1
2004 Wakatsuki T, Schlessinger J, Elson EL. The biochemical response of the heart to hypertension and exercise. Trends in Biochemical Sciences. 29: 609-17. PMID 15501680 DOI: 10.1016/j.tibs.2004.09.002  1
2004 Zhang KY, Card GL, Suzuki Y, Artis DR, Fong D, Gillette S, Hsieh D, Neiman J, West BL, Zhang C, Milburn MV, Kim SH, Schlessinger J, Bollag G. A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases. Molecular Cell. 15: 279-86. PMID 15260978 DOI: 10.1016/j.molcel.2004.07.005  1
2004 Lamothe B, Yamada M, Schaeper U, Birchmeier W, Lax I, Schlessinger J. The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway. Molecular and Cellular Biology. 24: 5657-66. PMID 15199124 DOI: 10.1128/MCB.24.13.5657-5666.2004  1
2004 Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J. FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. Febs Letters. 564: 14-8. PMID 15094036 DOI: 10.1016/S0014-5793(04)00287-X  1
2004 Thiberge S, Nechushtan A, Sprinzak D, Gileadi O, Behar V, Zik O, Chowers Y, Michaeli S, Schlessinger J, Moses E. Scanning electron microscopy of cells and tissues under fully hydrated conditions. Proceedings of the National Academy of Sciences of the United States of America. 101: 3346-51. PMID 14988502 DOI: 10.1073/pnas.0400088101  1
2004 Klein P, Mattoon D, Lemmon MA, Schlessinger J. A structure-based model for ligand binding and dimerization of EGF receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 929-34. PMID 14732694 DOI: 10.1073/pnas.0307285101  1
2004 Mattoon D, Klein P, Lemmon MA, Lax I, Schlessinger J. The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function. Proceedings of the National Academy of Sciences of the United States of America. 101: 923-8. PMID 14732693 DOI: 10.1073/pnas.0307286101  1
2004 Olsen SK, Ibrahimi OA, Raucci A, Zhang F, Eliseenkova AV, Yayon A, Basilico C, Linhardt RJ, Schlessinger J, Mohammadi M. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proceedings of the National Academy of Sciences of the United States of America. 101: 935-40. PMID 14732692 DOI: 10.1073/pnas.0307287101  1
2003 Okigaki M, Davis C, Falasca M, Harroch S, Felsenfeld DP, Sheetz MP, Schlessinger J. Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration. Proceedings of the National Academy of Sciences of the United States of America. 100: 10740-5. PMID 12960403 DOI: 10.1073/pnas.1834348100  1
2003 Schlessinger J, Lemmon MA. SH2 and PTB domains in tyrosine kinase signaling. Science's Stke : Signal Transduction Knowledge Environment. 2003: RE12. PMID 12865499 DOI: 10.1126/stke.2003.191.re12  1
2003 Schlessinger J. Signal transduction. Autoinhibition control. Science (New York, N.Y.). 300: 750-2. PMID 12730587 DOI: 10.1126/science.1082024  1
2002 Fleishman SJ, Schlessinger J, Ben-Tal N. A putative molecular-activation switch in the transmembrane domain of erbB2. Proceedings of the National Academy of Sciences of the United States of America. 99: 15937-40. PMID 12461170 DOI: 10.1073/pnas.252640799  1
2002 Lax I, Wong A, Lamothe B, Lee A, Frost A, Hawes J, Schlessinger J. The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors. Molecular Cell. 10: 709-19. PMID 12419216 DOI: 10.1016/S1097-2765(02)00689-5  1
2002 Harroch S, Furtado GC, Brueck W, Rosenbluth J, Lafaille J, Chao M, Buxbaum JD, Schlessinger J. A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions. Nature Genetics. 32: 411-4. PMID 12355066 DOI: 10.1038/ng1004  1
2002 Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell. 110: 669-72. PMID 12297041 DOI: 10.1016/S0092-8674(02)00966-2  1
2002 Schlessinger J. All signaling is local? Molecular Cell. 10: 218-9. PMID 12191465 DOI: 10.1016/S1097-2765(02)00607-X  1
2002 Wong A, Lamothe B, Lee A, Schlessinger J, Lax I, Li A. FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl. Proceedings of the National Academy of Sciences of the United States of America. 99: 6684-9. PMID 11997436 DOI: 10.1073/pnas.052138899  1
2002 Schlessinger J. A solid base for assaying protein kinase activity. Nature Biotechnology. 20: 232-3. PMID 11875418 DOI: 10.1038/nbt0302-232  1
2001 Hadari YR, Gotoh N, Kouhara H, Lax I, Schlessinger J. Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways. Proceedings of the National Academy of Sciences of the United States of America. 98: 8578-83. PMID 11447289 DOI: 10.1073/pnas.161259898  1
2001 Nishida M, Nagata K, Hachimori Y, Horiuchi M, Ogura K, Mandiyan V, Schlessinger J, Inagaki F. Novel recognition mode between Vav and Grb2 SH3 domains. The Embo Journal. 20: 2995-3007. PMID 11406576 DOI: 10.1093/emboj/20.12.2995  1
2001 Melillo RM, Santoro M, Ong SH, Billaud M, Fusco A, Hadari YR, Schlessinger J, Lax I. Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade. Molecular and Cellular Biology. 21: 4177-87. PMID 11390647 DOI: 10.1128/MCB.21.13.4177-4187.2001  1
2001 Ong SH, Hadari YR, Gotoh N, Guy GR, Schlessinger J, Lax I. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 6074-9. PMID 11353842 DOI: 10.1073/pnas.111114298  1
2001 Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, Okigaki M, Cary LA, Moolenaar WH, Schlessinger J. Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. The Journal of Biological Chemistry. 276: 20130-5. PMID 11274221 DOI: 10.1074/jbc.M102307200  1
2001 Stanzione R, Picascia A, Chieffi P, Imbimbo C, Palmieri A, Mirone V, Staibano S, Franco R, De Rosa G, Schlessinger J, Tramontano D. Variations of proline-rich kinase Pyk2 expression correlate with prostate cancer progression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 81: 51-9. PMID 11204274  1
2001 Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F. Solution structure of Grb2 reveals extensive flexibility necessary for target recognition. Journal of Molecular Biology. 306: 527-37. PMID 11178911 DOI: 10.1006/jmbi.2000.4396  1
2000 Thomas G, de Pablo F, Schlessinger J, Moscat J. The ins and outs of protein phosphorylation. Workshop report: control of signaling by protein phosphorylation. Embo Reports. 1: 11-5. PMID 11256615 DOI: 10.1093/embo-reports/kvd014  1
2000 Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 103: 211-25. PMID 11057895  1
2000 Schlessinger J, Plotnikov AN, Ibrahimi OA, Eliseenkova AV, Yeh BK, Yayon A, Linhardt RJ, Mohammadi M. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Molecular Cell. 6: 743-50. PMID 11030354  1
2000 Harroch S, Palmeri M, Rosenbluth J, Custer A, Okigaki M, Shrager P, Blum M, Buxbaum JD, Schlessinger J. No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta. Molecular and Cellular Biology. 20: 7706-15. PMID 11003666 DOI: 10.1128/MCB.20.20.7706-7715.2000  1
2000 Laird AD, Vajkoczy P, Shawver LK, Thurnher A, Liang C, Mohammadi M, Schlessinger J, Ullrich A, Hubbard SR, Blake RA, Fong TA, Strawn LM, Sun L, Tang C, Hawtin R, et al. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Research. 60: 4152-60. PMID 10945623  1
2000 Sibilia M, Fleischmann A, Behrens A, Stingl L, Carroll J, Watt FM, Schlessinger J, Wagner EF. The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell. 102: 211-20. PMID 10943841  1
2000 Zhang Z, Zhang R, Joachimiak A, Schlessinger J, Kong XP. Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation. Proceedings of the National Academy of Sciences of the United States of America. 97: 7732-7. PMID 10884405 DOI: 10.1073/pnas.97.14.7732  1
2000 Guinamard R, Okigaki M, Schlessinger J, Ravetch JV. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nature Immunology. 1: 31-6. PMID 10881171 DOI: 10.1038/76882  1
2000 Domagala T, Konstantopoulos N, Smyth F, Jorissen RN, Fabri L, Geleick D, Lax I, Schlessinger J, Sawyer W, Howlett GJ, Burgess AW, Nice EC. Stoichiometry, kinetic and binding analysis of the interaction between epidermal growth factor (EGF) and the extracellular domain of the EGF receptor. Growth Factors (Chur, Switzerland). 18: 11-29. PMID 10831070  1
2000 Plotnikov AN, Hubbard SR, Schlessinger J, Mohammadi M. Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity. Cell. 101: 413-24. PMID 10830168  1
2000 Schlessinger J. Novel fluorescent approaches for studying cell signaling in single cells. Nature Biotechnology. 18: 262-3. PMID 10700133 DOI: 10.1038/73687  1
2000 Schlessinger J. New roles for Src kinases in control of cell survival and angiogenesis. Cell. 100: 293-6. PMID 10676810  1
2000 Rodrigues GA, Falasca M, Zhang Z, Ong SH, Schlessinger J. A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling. Molecular and Cellular Biology. 20: 1448-59. PMID 10648629 DOI: 10.1128/MCB.20.4.1448-1459.2000  1
2000 Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Molecular and Cellular Biology. 20: 979-89. PMID 10629055 DOI: 10.1128/MCB.20.3.979-989.2000  1
1999 Mandiyan V, Andreev J, Schlessinger J, Hubbard SR. Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta. The Embo Journal. 18: 6890-8. PMID 10601011 DOI: 10.1093/emboj/18.24.6890  1
1999 Plotnikov AN, Schlessinger J, Hubbard SR, Mohammadi M. Structural basis for FGF receptor dimerization and activation. Cell. 98: 641-50. PMID 10490103 DOI: 10.1016/S0092-8674(00)80051-3  1
1999 Shen Z, Batzer A, Koehler JA, Polakis P, Schlessinger J, Lydon NB, Moran MF. Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src. Oncogene. 18: 4647-53. PMID 10467411 DOI: 10.1038/sj.onc.1203079  1
1999 Broome MA, Galisteo ML, Schlessinger J, Courtneidge SA. The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases. Oncogene. 18: 2908-12. PMID 10362262 DOI: 10.1038/sj.onc.1202873  1
1999 Ogura K, Tsuchiya S, Terasawa H, Yuzawa S, Hatanaka H, Mandiyan V, Schlessinger J, Inagaki F. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide. Journal of Molecular Biology. 289: 439-45. PMID 10356320 DOI: 10.1006/jmbi.1999.2792  1
1999 Tsuchiya S, Ogura K, Hatanaka H, Nagata K, Terasawa H, Mandiyan V, Schlessinger J, Aimoto S, Ohta H, Inagaki F. Solution structure of the SH2 domain of Grb2/Ash complexed with EGF receptor-derived phosphotyrosine-containing peptide. Journal of Biochemistry. 125: 1151-9. PMID 10348919  1
1999 Takaoka A, Tanaka N, Mitani Y, Miyazaki T, Fujii H, Sato M, Kovarik P, Decker T, Schlessinger J, Taniguchi T. Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling. The Embo Journal. 18: 2480-8. PMID 10228162 DOI: 10.1093/emboj/18.9.2480  1
1999 Ogura K, Nagata K, Hatanaka H, Habuchi H, Kimata K, Tate S, Ravera MW, Jaye M, Schlessinger J, Inagaki F. Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide. Journal of Biomolecular Nmr. 13: 11-24. PMID 10070748 DOI: 10.1023/A:1008330622467  1
1999 Andreev J, Simon JP, Sabatini DD, Kam J, Plowman G, Randazzo PA, Schlessinger J. Identification of a new Pyk2 target protein with Arf-GAP activity. Molecular and Cellular Biology. 19: 2338-50. PMID 10022920  1
1999 Lev S, Hernandez J, Martinez R, Chen A, Plowman G, Schlessinger J. Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. Molecular and Cellular Biology. 19: 2278-88. PMID 10022914  1
1998 Moreno H, Nadal M, Leznik E, Sugimori M, Lax I, Schlessinger J, Llinás R. Nerve growth factor acutely reduces chemical transmission by means of postsynaptic TrkA-like receptors in squid giant synapse. Proceedings of the National Academy of Sciences of the United States of America. 95: 14997-5002. PMID 9844004 DOI: 10.1073/pnas.95.25.14997  1
1998 Mohammadi M, Froum S, Hamby JM, Schroeder MC, Panek RL, Lu GH, Eliseenkova AV, Green D, Schlessinger J, Hubbard SR. Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain. The Embo Journal. 17: 5896-904. PMID 9774334 DOI: 10.1093/emboj/17.20.5896  1
1998 Weiss A, Schlessinger J. Switching signals on or off by receptor dimerization. Cell. 94: 277-80. PMID 9708728 DOI: 10.1016/S0092-8674(00)81469-5  1
1998 Wang Y, Falasca M, Schlessinger J, Malstrom S, Tsichlis P, Settleman J, Hu W, Lim B, Prywes R. Activation of the c-fos serum response element by phosphatidyl inositol 3-kinase and rho pathways in HeLa cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 513-22. PMID 9690619  1
1998 Lemmon MA, Schlessinger J. Transmembrane signaling by receptor oligomerization. Methods in Molecular Biology (Clifton, N.J.). 84: 49-71. PMID 9666441 DOI: 10.1385/0-89603-488-7:49  1
1998 DiGabriele AD, Lax I, Chen DI, Svahn CM, Jaye M, Schlessinger J, Hendrickson WA. Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature. 393: 812-7. PMID 9655399 DOI: 10.1038/31741  1
1998 Hadari YR, Kouhara H, Lax I, Schlessinger J. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. Molecular and Cellular Biology. 18: 3966-73. PMID 9632781  1
1998 Sorokin A, Reed E, Nnkemere N, Dulin NO, Schlessinger J. Crk protein binds to PDGF receptor and insulin receptor substrate-1 with different modulating effects on PDGF- and insulin-dependent signaling pathways. Oncogene. 16: 2425-34. PMID 9627109 DOI: 10.1038/sj.onc.1201781  1
1998 Dikic I, Dikic I, Schlessinger J. Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling. The Journal of Biological Chemistry. 273: 14301-8. PMID 9603937 DOI: 10.1074/jbc.273.23.14301  1
1998 Peles E, Schlessinger J, Grumet M. Multi-ligand interactions with receptor-like protein tyrosine phosphatase beta: implications for intercellular signaling. Trends in Biochemical Sciences. 23: 121-4. PMID 9584610 DOI: 10.1016/S0968-0004(98)01195-5  1
1998 Hubbard SR, Mohammadi M, Schlessinger J. Autoregulatory mechanisms in protein-tyrosine kinases. The Journal of Biological Chemistry. 273: 11987-90. PMID 9575136 DOI: 10.1074/jbc.273.20.11987  1
1998 Holland SJ, Peles E, Pawson T, Schlessinger J. Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta. Current Opinion in Neurobiology. 8: 117-27. PMID 9568399 DOI: 10.1016/S0959-4388(98)80015-9  1
1998 Abe Y, Odaka M, Inagaki F, Lax I, Schlessinger J, Kohda D. Disulfide bond structure of human epidermal growth factor receptor. The Journal of Biological Chemistry. 273: 11150-7. PMID 9556602 DOI: 10.1074/jbc.273.18.11150  1
1998 Miyazaki T, Takaoka A, Nogueira L, Dikic I, Fujii H, Tsujino S, Mitani Y, Maeda M, Schlessinger J, Taniguchi T. Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway. Genes & Development. 12: 770-5. PMID 9512511  1
1998 Falasca M, Logan SK, Lehto VP, Baccante G, Lemmon MA, Schlessinger J. Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. The Embo Journal. 17: 414-22. PMID 9430633 DOI: 10.1093/emboj/17.2.414  1
1997 M A L, M F, J S, K F. Regulatory recruitment of signalling molecules to the cell membrane by pleckstrinhomology domains. Trends in Cell Biology. 7: 237-42. PMID 17708952 DOI: 10.1016/S0962-8924(97)01065-9  1
1997 Schlessinger J. Direct binding and activation of receptor tyrosine kinases by collagen. Cell. 91: 869-72. PMID 9428509 DOI: 10.1016/S0092-8674(00)80477-8  1
1997 Ogura K, Tsuchiya S, Terasawa H, Yuzawa S, Hatanaka H, Mandiyan V, Schlessinger J, Inagaki F. Conformation of an Shc-derived phosphotyrosine-containing peptide complexed with the Grb2 SH2 domain. Journal of Biomolecular Nmr. 10: 273-8. PMID 9390405  1
1997 Davis CB, Dikic I, Unutmaz D, Hill CM, Arthos J, Siani MA, Thompson DA, Schlessinger J, Littman DR. Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5. The Journal of Experimental Medicine. 186: 1793-8. PMID 9362541 DOI: 10.1084/jem.186.10.1793  1
1997 Zhang Z, Lee CH, Mandiyan V, Borg JP, Margolis B, Schlessinger J, Kuriyan J. Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. The Embo Journal. 16: 6141-50. PMID 9321393 DOI: 10.1093/emboj/16.20.6141  1
1997 Logan SK, Falasca M, Hu P, Schlessinger J. Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway. Molecular and Cellular Biology. 17: 5784-90. PMID 9315636  1
1997 Odaka M, Kohda D, Lax I, Schlessinger J, Inagaki F. Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor. Journal of Biochemistry. 122: 116-21. PMID 9276679  1
1997 Rodrigues GA, Park M, Schlessinger J. Activation of the JNK pathway is essential for transformation by the Met oncogene. The Embo Journal. 16: 2634-45. PMID 9184210 DOI: 10.1093/emboj/16.10.2634  1
1997 Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell. 89: 693-702. PMID 9182757  1
1997 Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, Hubbard SR, Schlessinger J. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science (New York, N.Y.). 276: 955-60. PMID 9139660 DOI: 10.1126/science.276.5314.955  1
1997 Artalejo CR, Lemmon MA, Schlessinger J, Palfrey HC. Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells. The Embo Journal. 16: 1565-74. PMID 9130701 DOI: 10.1093/emboj/16.7.1565  1
1997 Peles E, Nativ M, Lustig M, Grumet M, Schilling J, Martinez R, Plowman GD, Schlessinger J. Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions. The Embo Journal. 16: 978-88. PMID 9118959 DOI: 10.1093/emboj/16.5.978  1
1997 Peles E, Joho K, Plowman GD, Schlessinger J. Close similarity between Drosophila neurexin IV and mammalian Caspr protein suggests a conserved mechanism for cellular interactions. Cell. 88: 745-6. PMID 9118217  1
1997 Qian D, Lev S, van Oers NS, Dikic I, Schlessinger J, Weiss A. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. The Journal of Experimental Medicine. 185: 1253-9. PMID 9104812 DOI: 10.1084/jem.185.7.1253  1
1997 Schlessinger J. Phospholipase Cgamma activation and phosphoinositide hydrolysis are essential for embryonal development. Proceedings of the National Academy of Sciences of the United States of America. 94: 2798-9. PMID 9096299 DOI: 10.1073/pnas.94.7.2798  1
1997 Llinás R, Moreno H, Sugimori M, Mohammadi M, Schlessinger J. Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 94: 1990-4. PMID 9050892 DOI: 10.1073/pnas.94.5.1990  1
1997 Sakurai T, Lustig M, Nativ M, Hemperly JJ, Schlessinger J, Peles E, Grumet M. Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta. The Journal of Cell Biology. 136: 907-18. PMID 9049255 DOI: 10.1083/jcb.136.4.907  1
1997 Lemmon MA, Pinchasi D, Zhou M, Lax I, Schlessinger J. Kit receptor dimerization is driven by bivalent binding of stem cell factor. The Journal of Biological Chemistry. 272: 6311-7. PMID 9045650 DOI: 10.1074/jbc.272.10.6311  1
1997 Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J. Two EGF molecules contribute additively to stabilization of the EGFR dimer. The Embo Journal. 16: 281-94. PMID 9029149 DOI: 10.1093/emboj/16.2.281  1
1996 Schlessinger J. Interferon regulatory factors (IRFs); providing the molecular link between cytokine action and host defense. Japanese Journal of Cancer Research : Gann. 87: inside front cover. PMID 8957056  1
1996 Sahni M, Zhou XM, Bakiri L, Schlessinger J, Baron R, Levy JB. Identification of a novel 135-kDa Grb2-binding protein in osteoclasts. The Journal of Biological Chemistry. 271: 33141-7. PMID 8955163 DOI: 10.1074/jbc.271.51.33141  1
1996 Roghani M, Mohammadi M, Schlessinger J, Moscatelli D. Induction of urokinase-type plasminogen activator by fibroblast growth factor (FGF)-2 is dependent on expression of FGF receptors and does not require activation of phospholipase Cgamma1. The Journal of Biological Chemistry. 271: 31154-9. PMID 8940113 DOI: 10.1074/jbc.271.49.31154  1
1996 Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature. 383: 547-50. PMID 8849729 DOI: 10.1038/383547a0  1
1996 Galisteo ML, Chernoff J, Su YC, Skolnik EY, Schlessinger J. The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. The Journal of Biological Chemistry. 271: 20997-1000. PMID 8798379 DOI: 10.1074/jbc.271.35.20997  1
1996 Mohammadi M, Schlessinger J, Hubbard SR. Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism. Cell. 86: 577-87. PMID 8752212  0.52
1996 Tokiwa G, Dikic I, Lev S, Schlessinger J. Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science (New York, N.Y.). 273: 792-4. PMID 8670418  1
1996 Lemmon MA, Ferguson KM, Schlessinger J. PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell. 85: 621-4. PMID 8646770 DOI: 10.1016/S0092-8674(00)81022-3  1
1996 Yenush L, Fernandez R, Myers MG, Grammer TC, Sun XJ, Blenis J, Pierce JH, Schlessinger J, White MF. The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis. Molecular and Cellular Biology. 16: 2509-17. PMID 8628319  1
1996 Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M, Schlessinger J. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. Molecular and Cellular Biology. 16: 977-89. PMID 8622701  0.52
1996 Mandiyan V, O'Brien R, Zhou M, Margolis B, Lemmon MA, Sturtevant JM, Schlessinger J. Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif. The Journal of Biological Chemistry. 271: 4770-5. PMID 8617744 DOI: 10.1074/jbc.271.9.4770  1
1996 Nolte RT, Eck MJ, Schlessinger J, Shoelson SE, Harrison SC. Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes. Nature Structural Biology. 3: 364-74. PMID 8599763  1
1996 Zheng J, Cahill SM, Lemmon MA, Fushman D, Schlessinger J, Cowburn D. Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity. Journal of Molecular Biology. 255: 14-21. PMID 8568861 DOI: 10.1006/jmbi.1996.0002  1
1996 Leaman DW, Pisharody S, Flickinger TW, Commane MA, Schlessinger J, Kerr IM, Levy DE, Stark GR. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Molecular and Cellular Biology. 16: 369-75. PMID 8524316  1
1996 Hubbard SR, Mohammadi M, Schlessinger J, Wei L, Ellis L, Hendrickson WA. Structural studies of receptor tyrosine kinases Faseb Journal. 10: A987.  1
1995 Margolis B, Skolnik EY, Schlessinger J. Use of tyrosine-phosphorylated proteins to screen bacterial expression libraries for SH2 domains. Methods in Enzymology. 255: 360-9. PMID 8524121  0.4
1995 Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell. 83: 1037-46. PMID 8521504 DOI: 10.1016/0092-8674(95)90219-8  1
1995 Schlessinger J, Lax I, Lemmon M. Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? Cell. 83: 357-60. PMID 8521464  0.44
1995 Fushman D, Cahill S, Lemmon MA, Schlessinger J, Cowburn D. Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 92: 816-20. PMID 7846058  0.96
1995 Songyang Z, Carraway KL, Eck MJ, Harrison SC, Feldman RA, Mohammadi M, Schlessinger J, Hubbard SR, Smith DP, Eng C. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature. 373: 536-9. PMID 7845468 DOI: 10.1038/373536a0  1
1995 den Hertog J, Sap J, Pals CE, Schlessinger J, Kruijer W. Stimulation of receptor protein-tyrosine phosphatase alpha activity and phosphorylation by phorbol ester. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 303-7. PMID 7794797  1
1995 Fernandez R, Tabarini D, Azpiazu N, Frasch M, Schlessinger J. The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. The Embo Journal. 14: 3373-84. PMID 7628438  1
1995 Peles E, Nativ M, Campbell PL, Sakurai T, Martinez R, Lev S, Clary DO, Schilling J, Barnea G, Plowman GD, Grumet M, Schlessinger J. The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin. Cell. 82: 251-60. PMID 7628014 DOI: 10.1016/0092-8674(95)90312-7  1
1995 Wang H, Yan H, Canoll PD, Silvennoinen O, Schlessinger J, Musacchio JM. Expression of receptor protein tyrosine phosphatase-sigma (RPTP-sigma) in the nervous system of the developing and adult rat. Journal of Neuroscience Research. 41: 297-310. PMID 7563223 DOI: 10.1002/jnr.490410303  0.32
1995 Mainiero F, Pepe A, Wary KK, Spinardi L, Mohammadi M, Schlessinger J, Giancotti FG. Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. The Embo Journal. 14: 4470-81. PMID 7556090  0.52
1995 Ferguson KM, Lemmon MA, Sigler PB, Schlessinger J. Scratching the surface with the PH domain. Nature Structural Biology. 2: 715-8. PMID 7552736 DOI: 10.1038/nsb0995-715  1
1995 Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J. Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. Nature. 376: 737-45. PMID 7544443 DOI: 10.1038/376737a0  1
1995 Batzer AG, Blaikie P, Nelson K, Schlessinger J, Margolis B. The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor. Molecular and Cellular Biology. 15: 4403-9. PMID 7542744  0.4
1995 Dikic I, Batzer AG, Blaikie P, Obermeier A, Ullrich A, Schlessinger J, Margolis B. Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain. The Journal of Biological Chemistry. 270: 15125-9. PMID 7541035  0.4
1995 Herbst R, Shearman MS, Jallal B, Schlessinger J, Ullrich A. Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro. Biochemistry. 34: 5971-9. PMID 7537096  0.4
1995 Ladbury JE, Lemmon MA, Zhou M, Green J, Botfield MC, Schlessinger J. Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proceedings of the National Academy of Sciences of the United States of America. 92: 3199-203. PMID 7536927  0.96
1995 Huang J, Mohammadi M, Rodrigues GA, Schlessinger J. Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis. The Journal of Biological Chemistry. 270: 5065-72. PMID 7534287  0.52
1995 Obermeier A, Bradshaw RA, Seedorf K, Choidas A, Schlessinger J, Ullrich A. Definition of signals for neuronal differentiation. Annals of the New York Academy of Sciences. 766: 1-17. PMID 7486648 DOI: 10.1111/j.1749-6632.1995.tb26643.x  1
1995 Lemmon MA, Ferguson KM, O'Brien R, Sigler PB, Schlessinger J. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proceedings of the National Academy of Sciences of the United States of America. 92: 10472-6. PMID 7479822 DOI: 10.1073/pnas.92.23.10472  1
1994 Barnea G, Grumet M, Sap J, Margolis RU, Schlessinger J. Close similarity between receptor-linked tyrosine phosphatase and rat brain proteoglycan. Cell. 76: 205. PMID 8293458 DOI: 10.1016/0092-8674(94)90328-X  1
1994 Sap J, Jiang YP, Friedlander D, Grumet M, Schlessinger J. Receptor tyrosine phosphatase R-PTP-kappa mediates homophilic binding. Molecular and Cellular Biology. 14: 1-9. PMID 8264577  1
1994 Seedorf K, Kostka G, Lammers R, Bashkin P, Daly R, Burgess WH, van der Bliek AM, Schlessinger J, Ullrich A. Dynamin binds to SH3 domains of phospholipase C gamma and GRB-2. The Journal of Biological Chemistry. 269: 16009-14. PMID 8206897  0.4
1994 Obermeier A, Bradshaw RA, Seedorf K, Choidas A, Schlessinger J, Ullrich A. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. The Embo Journal. 13: 1585-90. PMID 8156997  1
1994 Daum G, Regenass S, Sap J, Schlessinger J, Fischer EH. Multiple forms of the human tyrosine phosphatase RPTP alpha. Isozymes and differences in glycosylation. The Journal of Biological Chemistry. 269: 10524-8. PMID 8144638  1
1994 Sorokin A, Lemmon MA, Ullrich A, Schlessinger J. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond. The Journal of Biological Chemistry. 269: 9752-9. PMID 8144568  0.96
1994 Hu P, Schlessinger J. Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta. Molecular and Cellular Biology. 14: 2577-83. PMID 8139559  1
1994 Desai DM, Sap J, Silvennoinen O, Schlessinger J, Weiss A. The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation. The Embo Journal. 13: 4002-10. PMID 8076596  1
1994 Hobert O, Jallal B, Schlessinger J, Ullrich A. Novel signaling pathway suggested by SH3 domain-mediated p95vav/heterogeneous ribonucleoprotein K interaction. The Journal of Biological Chemistry. 269: 20225-8. PMID 8051112  1
1994 McPherson PS, Czernik AJ, Chilcote TJ, Onofri F, Benfenati F, Greengard P, Schlessinger J, De Camilli P. Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I. Proceedings of the National Academy of Sciences of the United States of America. 91: 6486-90. PMID 8022809 DOI: 10.1073/pnas.91.14.6486  1
1994 Li N, Schlessinger J, Margolis B. Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins. Oncogene. 9: 3457-65. PMID 7970705  0.4
1994 Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin. Cell. 79: 199-209. PMID 7954789 DOI: 10.1016/0092-8674(94)90190-2  1
1994 Dikic I, Schlessinger J, Lax I. PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Current Biology : Cb. 4: 702-8. PMID 7953556  0.44
1994 Salmon SE, Lam KS, Felder S, Yeoman H, Schlessinger J, Ullrich A, Krchnák V, Lebl M. One bead, one chemical compound: use of the selectide process for anticancer drug discovery. Acta Oncologica (Stockholm, Sweden). 33: 127-31. PMID 7911310 DOI: 10.3109/02841869409098395  1
1994 Kohda D, Terasawa H, Ichikawa S, Ogura K, Hatanaka H, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F. Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. Structure (London, England : 1993). 2: 1029-40. PMID 7881903  0.48
1994 Lemmon MA, Schlessinger J. Regulation of signal transduction and signal diversity by receptor oligomerization. Trends in Biochemical Sciences. 19: 459-63. PMID 7855887  0.96
1994 Terasawa H, Kohda D, Hatanaka H, Tsuchiya S, Ogura K, Nagata K, Ishii S, Mandiyan V, Ullrich A, Schlessinger J. Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos. Nature Structural Biology. 1: 891-7. PMID 7773778  0.48
1994 Schlessinger J, Bar-Sagi D. Activation of Ras and other signaling pathways by receptor tyrosine kinases. Cold Spring Harbor Symposia On Quantitative Biology. 59: 173-9. PMID 7587067  1
1994 Spivak-Kroizman T, Lemmon MA, Dikic I, Ladbury JE, Pinchasi D, Huang J, Jaye M, Crumley G, Schlessinger J, Lax I. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell. 79: 1015-24. PMID 7528103  0.96
1994 Lemmon MA, Ladbury JE, Mandiyan V, Zhou M, Schlessinger J. Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2. The Journal of Biological Chemistry. 269: 31653-8. PMID 7527391  0.96
1994 Lee CH, Kominos D, Jacques S, Margolis B, Schlessinger J, Shoelson SE, Kuriyan J. Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure (London, England : 1993). 2: 423-38. PMID 7521735 DOI: 10.1016/S0969-2126(00)00044-7  1
1994 Batzer AG, Rotin D, Ureña JM, Skolnik EY, Schlessinger J. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Molecular and Cellular Biology. 14: 5192-201. PMID 7518560  1
1994 Sorokin A, Mohammadi M, Huang J, Schlessinger J. Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766. The Journal of Biological Chemistry. 269: 17056-61. PMID 7516330  0.52
1994 Spivak-Kroizman T, Mohammadi M, Hu P, Jaye M, Schlessinger J, Lax I. Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells. The Journal of Biological Chemistry. 269: 14419-23. PMID 7514169  0.52
1994 Barnea G, Grumet M, Milev P, Silvennoinen O, Levy JB, Sap J, Schlessinger J. Receptor tyrosine phosphatase beta is expressed in the form of proteoglycan and binds to the extracellular matrix protein tenascin. The Journal of Biological Chemistry. 269: 14349-52. PMID 7514167  1
1993 Chardin P, Camonis JH, Gale NW, van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science (New York, N.Y.). 260: 1338-43. PMID 8493579  1
1993 Desai DM, Sap J, Schlessinger J, Weiss A. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell. 73: 541-54. PMID 8490965 DOI: 10.1016/0092-8674(93)90141-C  1
1993 Hu P, Margolis B, Schlessinger J. Vav: a potential link between tyrosine kinases and ras-like GTPases in hematopoietic cell signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 179-83. PMID 8489524 DOI: 10.1002/bies.950150306  0.4
1993 Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature. 363: 85-8. PMID 8479541 DOI: 10.1038/363085a0  1
1993 Jiang YP, Wang H, D'Eustachio P, Musacchio JM, Schlessinger J, Sap J. Cloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular region. Molecular and Cellular Biology. 13: 2942-51. PMID 8474452  1
1993 Olivier JP, Raabe T, Henkemeyer M, Dickson B, Mbamalu G, Margolis B, Schlessinger J, Hafen E, Pawson T. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell. 73: 179-91. PMID 8462098 DOI: 10.1016/0092-8674(93)90170-U  1
1993 Kohda D, Odaka M, Lax I, Kawasaki H, Suzuki K, Ullrich A, Schlessinger J, Inagaki F. A 40-kDa epidermal growth factor/transforming growth factor alpha-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor. The Journal of Biological Chemistry. 268: 1976-81. PMID 8420971  0.44
1993 Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell. 75: 175-85. PMID 8402896  1
1993 Mohammadi M, Honegger A, Sorokin A, Ullrich A, Schlessinger J, Hurwitz DR. Aggregation-induced activation of the epidermal growth factor receptor protein tyrosine kinase. Biochemistry. 32: 8742-8. PMID 8395880  1
1993 Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature. 363: 88-92. PMID 8386805 DOI: 10.1038/363088a0  1
1993 Piccione E, Case RD, Domchek SM, Hu P, Chaudhuri M, Backer JM, Schlessinger J, Shoelson SE. Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding. Biochemistry. 32: 3197-202. PMID 8384875  0.32
1993 Obermeier A, Halfter H, Wiesmüller KH, Jung G, Schlessinger J, Ullrich A. Tyrosine 785 is a major determinant of Trk--substrate interaction. The Embo Journal. 12: 933-41. PMID 8384556  0.4
1993 Shoelson SE, Sivaraja M, Williams KP, Hu P, Schlessinger J, Weiss MA. Specific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activation. The Embo Journal. 12: 795-802. PMID 8382612  1
1993 Silvennoinen O, Schindler C, Schlessinger J, Levy DE. Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science (New York, N.Y.). 261: 1736-9. PMID 8378775  0.32
1993 Zhou M, Felder S, Rubinstein M, Hurwitz DR, Ullrich A, Lax I, Schlessinger J. Real-time measurements of kinetics of EGF binding to soluble EGF receptor monomers and dimers support the dimerization model for receptor activation. Biochemistry. 32: 8193-8. PMID 8347619  0.44
1993 Bar-Sagi D, Rotin D, Batzer A, Mandiyan V, Schlessinger J. SH3 domains direct cellular localization of signaling molecules. Cell. 74: 83-91. PMID 8334708 DOI: 10.1016/0092-8674(93)90296-3  1
1993 Skolnik EY, Batzer A, Li N, Lee CH, Lowenstein E, Mohammadi M, Margolis B, Schlessinger J. The function of GRB2 in linking the insulin receptor to Ras signaling pathways. Science (New York, N.Y.). 260: 1953-5. PMID 8316835  1
1993 Stern MJ, Marengere LE, Daly RJ, Lowenstein EJ, Kokel M, Batzer A, Olivier P, Pawson T, Schlessinger J. The human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5. Molecular Biology of the Cell. 4: 1175-88. PMID 8305738  1
1993 Lee CH, Li W, Nishimura R, Zhou M, Batzer AG, Myers MG, White MF, Schlessinger J, Skolnik EY. Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 11713-7. PMID 8265614  1
1993 Canoll PD, Barnea G, Levy JB, Sap J, Ehrlich M, Silvennoinen O, Schlessinger J, Musacchio JM. The expression of a novel receptor-type tyrosine phosphatase suggests a role in morphogenesis and plasticity of the nervous system. Brain Research. Developmental Brain Research. 75: 293-8. PMID 8261619 DOI: 10.1016/0165-3806(93)90035-9  1
1993 Yan H, Grossman A, Wang H, D'Eustachio P, Mossie K, Musacchio JM, Silvennoinen O, Schlessinger J. A novel receptor tyrosine phosphatase-sigma that is highly expressed in the nervous system. The Journal of Biological Chemistry. 268: 24880-6. PMID 8227050  0.32
1993 Obermeier A, Lammers R, Wiesmüller KH, Jung G, Schlessinger J, Ullrich A. Identification of Trk binding sites for SHC and phosphatidylinositol 3'-kinase and formation of a multimeric signaling complex. The Journal of Biological Chemistry. 268: 22963-6. PMID 8226808  0.4
1993 Futter CE, Felder S, Schlessinger J, Ullrich A, Hopkins CR. Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor. The Journal of Cell Biology. 120: 77-83. PMID 8093248  1
1993 Lammers R, Bossenmaier B, Cool DE, Tonks NK, Schlessinger J, Fischer EH, Ullrich A. Differential activities of protein tyrosine phosphatases in intact cells. The Journal of Biological Chemistry. 268: 22456-62. PMID 7693671  0.4
1993 Nishimura R, Li W, Kashishian A, Mondino A, Zhou M, Cooper J, Schlessinger J. Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor. Molecular and Cellular Biology. 13: 6889-96. PMID 7692233  0.32
1993 Shearman MS, Herbst R, Schlessinger J, Ullrich A. Phosphatidylinositol 3'-kinase associates with p145c-kit as part of a cell type characteristic multimeric signalling complex. The Embo Journal. 12: 3817-26. PMID 7691598  0.4
1993 Kohda D, Hatanaka H, Odaka M, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F. Solution structure of the SH3 domain of phospholipase C-gamma. Cell. 72: 953-60. PMID 7681365  0.48
1993 Felder S, Zhou M, Hu P, Ureña J, Ullrich A, Chaudhuri M, White M, Shoelson SE, Schlessinger J. SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange. Molecular and Cellular Biology. 13: 1449-55. PMID 7680095  1
1993 Schumacher R, Soos MA, Schlessinger J, Brandenburg D, Siddle K, Ullrich A. Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants. The Journal of Biological Chemistry. 268: 1087-94. PMID 7678247  0.4
1993 Silvennoinen O, Ihle JN, Schlessinger J, Levy DE. Interferon-induced nuclear signalling by Jak protein tyrosine kinases. Nature. 366: 583-5. PMID 7504785 DOI: 10.1038/366583a0  1
1992 Rao VV, Löffler C, Sap J, Schlessinger J, Hansmann I. The gene for receptor-linked protein-tyrosine-phosphatase (PTPA) is assigned to human chromosome 20p12-pter by in situ hybridization (ISH and FISH). Genomics. 13: 906-7. PMID 1639427 DOI: 10.1016/0888-7543(92)90186-V  1
1992 Dionne CA, Modi WS, Crumley G, O'Brien SJ, Schlessinger J, Jaye M. BEK, a receptor for multiple members of the fibroblast growth factor (FGF) family, maps to human chromosome 10q25.3----q26. Cytogenetics and Cell Genetics. 60: 34-6. PMID 1582255 DOI: 10.1159/000133290  1
1992 Felder S, LaVin J, Ullrich A, Schlessinger J. Kinetics of binding, endocytosis, and recycling of EGF receptor mutants. The Journal of Cell Biology. 117: 203-12. PMID 1556153  1
1992 Rotin D, Margolis B, Mohammadi M, Daly RJ, Daum G, Li N, Fischer EH, Burgess WH, Ullrich A, Schlessinger J. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma. The Embo Journal. 11: 559-67. PMID 1537335  1
1992 Li W, Deanin GG, Margolis B, Schlessinger J, Oliver JM. Fc epsilon R1-mediated tyrosine phosphorylation of multiple proteins, including phospholipase C gamma 1 and the receptor beta gamma 2 complex, in RBL-2H3 rat basophilic leukemia cells. Molecular and Cellular Biology. 12: 3176-82. PMID 1535686  0.4
1992 Margolis B, Hu P, Katzav S, Li W, Oliver JM, Ullrich A, Weiss A, Schlessinger J. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature. 356: 71-4. PMID 1531699 DOI: 10.1038/356071a0  0.4
1992 Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature. 360: 689-92. PMID 1465135 DOI: 10.1038/360689a0  1
1992 Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J. High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proceedings of the National Academy of Sciences of the United States of America. 89: 8894-8. PMID 1409582  0.4
1992 Seedorf K, Millauer B, Kostka G, Schlessinger J, Ullrich A. Differential effects of carboxy-terminal sequence deletions on platelet-derived growth factor receptor signaling activities and interactions with cellular substrates. Molecular and Cellular Biology. 12: 4347-56. PMID 1406626  0.4
1992 Drabkin HA, Mendez MJ, Rabbitts PH, Varkony T, Bergh J, Schlessinger J, Erickson P, Gemmill RM. Characterization of the submicroscopic deletion in the small-cell lung carcinoma (SCLC) cell line U2020. Genes, Chromosomes & Cancer. 5: 67-74. PMID 1384664 DOI: 10.1002/gcc.2870050110  1
1992 Backer JM, Myers MG, Shoelson SE, Chin DJ, Sun XJ, Miralpeix M, Hu P, Margolis B, Skolnik EY, Schlessinger J. Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation. The Embo Journal. 11: 3469-79. PMID 1380456  1
1992 Mohammadi M, Dionne CA, Li W, Li N, Spivak T, Honegger AM, Jaye M, Schlessinger J. Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature. 358: 681-4. PMID 1379698 DOI: 10.1038/358681a0  1
1992 Herbst R, Shearman MS, Obermeier A, Schlessinger J, Ullrich A. Differential effects of W mutations on p145c-kit tyrosine kinase activity and substrate interaction. The Journal of Biological Chemistry. 267: 13210-6. PMID 1377679  0.4
1992 Hu P, Margolis B, Skolnik EY, Lammers R, Ullrich A, Schlessinger J. Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Molecular and Cellular Biology. 12: 981-90. PMID 1372091  0.4
1992 Spivak-Kroizman T, Rotin D, Pinchasi D, Ullrich A, Schlessinger J, Lax I. Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. The Journal of Biological Chemistry. 267: 8056-63. PMID 1349015  1
1992 Jallal B, Schlessinger J, Ullrich A. Tyrosine phosphatase inhibition permits analysis of signal transduction complexes in p185HER2/neu-overexpressing human tumor cells. The Journal of Biological Chemistry. 267: 4357-63. PMID 1347042  0.4
1992 Redemann N, Holzmann B, von Rüden T, Wagner EF, Schlessinger J, Ullrich A. Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants. Molecular and Cellular Biology. 12: 491-8. PMID 1346334  0.4
1992 Schlessinger J, Mohammadi M, Margolis B, Ullrich A. Role of SH2-containing proteins in cellular signaling by receptor tyrosine kinases. Cold Spring Harbor Symposia On Quantitative Biology. 57: 67-74. PMID 1339705  0.52
1992 Li W, Hu P, Skolnik EY, Ullrich A, Schlessinger J. The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Molecular and Cellular Biology. 12: 5824-33. PMID 1333047  0.4
1992 Myers MG, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF. IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85. Proceedings of the National Academy of Sciences of the United States of America. 89: 10350-4. PMID 1332046  1
1992 Schlessinger J, Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron. 9: 383-91. PMID 1326293  0.4
1992 Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D, Schlessinger J. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell. 70: 431-42. PMID 1322798 DOI: 10.1016/0092-8674(92)90167-B  1
1992 Jaye M, Schlessinger J, Dionne CA. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochimica Et Biophysica Acta. 1135: 185-99. PMID 1319744 DOI: 10.1016/0167-4889(92)90136-Y  1
1992 Rotin D, Honegger AM, Margolis BL, Ullrich A, Schlessinger J. Presence of SH2 domains of phospholipase C gamma 1 enhances substrate phosphorylation by increasing the affinity toward the epidermal growth factor receptor. The Journal of Biological Chemistry. 267: 9678-83. PMID 1315766  0.48
1992 Ballotti R, Baron V, Gautier N, Hainaut P, Scimeca JC, Dolais-Kitabgi J, Lammers R, Schlessinger J, Ullrich A, Van Obberghen E. Activation and regulation of the insulin receptor kinase. DiabèTe & MéTabolisme. 18: 98-103. PMID 1314199  1
1992 Tartare S, Ballotti R, Lammers R, Filloux C, Chauvel A, Schlessinger J, Ullrich A, Van Obberghen E. Activation of insulin-epidermal growth factor (EGF) receptor chimerae regulates EGF receptor binding affinity. The Journal of Cell Biology. 116: 627-33. PMID 1309816  0.4
1991 Crumley G, Bellot F, Kaplow JM, Schlessinger J, Jaye M, Dionne CA. High-affinity binding and activation of a truncated FGF receptor by both aFGF and bFGF. Oncogene. 6: 2255-62. PMID 1722570  1
1991 Herbst R, Lammers R, Schlessinger J, Ullrich A. Substrate phosphorylation specificity of the human c-kit receptor tyrosine kinase. The Journal of Biological Chemistry. 266: 19908-16. PMID 1718957  0.4
1991 Kashles O, Yarden Y, Fischer R, Ullrich A, Schlessinger J. A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization. Molecular and Cellular Biology. 11: 1454-63. PMID 1705006  1
1991 Hurwitz DR, Emanuel SL, Nathan MH, Sarver N, Ullrich A, Felder S, Lax I, Schlessinger J. EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain. The Journal of Biological Chemistry. 266: 22035-43. PMID 1657987  1
1988 Livneh E, Dull TJ, Berent E, Prywes R, Ullrich A, Schlessinger J. Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor. Molecular and Cellular Biology. 8: 2302-8. PMID 3136317  0.4
1988 Seger R, Yarden Y, Kashles O, Goldblatt D, Schlessinger J, Shaltiel S. The epidermal growth factor receptor as a substrate for a kinase-splitting membranal proteinase. The Journal of Biological Chemistry. 263: 3496-500. PMID 2830286  1
1987 Yarden Y, Schlessinger J. Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor. Biochemistry. 26: 1443-51. PMID 3494473  1
1987 Yarden Y, Schlessinger J. Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation. Biochemistry. 26: 1434-42. PMID 3494472  1
1987 Yarden Y, Kuang WJ, Yang-Feng T, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Francke U, Ullrich A. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. The Embo Journal. 6: 3341-51. PMID 2448137  1
1986 Prywes R, Livneh E, Ullrich A, Schlessinger J. Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization. The Embo Journal. 5: 2179-90. PMID 3490969  0.4
1986 Ullrich A, Riedel H, Yarden Y, Coussens L, Gray A, Dull T, Schlessinger J, Waterfield MD, Parker PJ. Protein kinases in cellular signal transduction: tyrosine kinase growth factor receptors and protein kinase C. Cold Spring Harbor Symposia On Quantitative Biology. 51: 713-24. PMID 3472757  1
1986 Livneh E, Prywes R, Kashles O, Reiss N, Sasson I, Mory Y, Ullrich A, Schlessinger J. Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. The Journal of Biological Chemistry. 261: 12490-7. PMID 3017977  0.4
1986 Livneh E, Benveniste M, Prywes R, Felder S, Kam Z, Schlessinger J. Large deletions in the cytoplasmic kinase domain of the epidermal growth factor receptor do not affect its laternal mobility. The Journal of Cell Biology. 103: 327-31. PMID 3015981  1
1986 Zidovetzki R, Yarden Y, Schlessinger J, Jovin TM. Microaggregation of hormone-occupied epidermal growth factor receptors on plasma membrane preparations. The Embo Journal. 5: 247-50. PMID 3011399  1
1985 Yarden Y, Schlessinger J. The EGF receptor kinase: evidence for allosteric activation and intramolecular self-phosphorylation. Ciba Foundation Symposium. 116: 23-45. PMID 3000707  1
1985 Yarden Y, Harari I, Schlessinger J. Purification of an active EGF receptor kinase with monoclonal antireceptor antibodies. The Journal of Biological Chemistry. 260: 315-9. PMID 2578126  1
1984 Ullrich A, Coussens L, Hayflick JS, Dull TJ, Gray A, Tam AW, Lee J, Yarden Y, Libermann TA, Schlessinger J. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature. 309: 418-25. PMID 6328312  1
1984 Downward J, Yarden Y, Mayes E, Scrace G, Totty N, Stockwell P, Ullrich A, Schlessinger J, Waterfield MD. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature. 307: 521-7. PMID 6320011  1
1984 Libermann TA, Razon N, Bartal AD, Yarden Y, Schlessinger J, Soreq H. Expression of epidermal growth factor receptors in human brain tumors. Cancer Research. 44: 753-60. PMID 6318976  1
1984 Lax I, Bar-Eli M, Yarden Y, Libermann TA, Schlessinger J. Antibodies to two defined regions of the transforming protein pp60src interact specifically with the epidermal growth factor receptor kinase system. Proceedings of the National Academy of Sciences of the United States of America. 81: 5911-5. PMID 6207534 DOI: 10.1073/pnas.81.19.5911  1
1983 Schlessinger J, Schreiber AB, Levi A, Lax I, Libermann T, Yarden Y. Regulation of cell proliferation by epidermal growth factor. Crc Critical Reviews in Biochemistry. 14: 93-111. PMID 6301752 DOI: 10.3109/10409238309102791  1
1983 Schreiber AB, Libermann TA, Lax I, Yarden Y, Schlessinger J. Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies. The Journal of Biological Chemistry. 258: 846-53. PMID 6296087  1
1983 Gooi HC, Schlessinger J, Lax I, Yarden Y, Libermann TA, Feizi T. Monoclonal antibody reactive with the human epidermal-growth-factor receptor recognizes the blood-group-A antigen. Bioscience Reports. 3: 1045-52. PMID 6198005 DOI: 10.1007/BF01121031  1
1983 Hapgood J, Libermann TA, Lax I, Yarden Y, Schreiber AB, Naor Z, Schlessinger J. Monoclonal antibodies against epidermal growth factor receptor induce prolactin synthesis in cultured rat pituitary cells (GH3). Proceedings of the National Academy of Sciences of the United States of America. 80: 6451-5. PMID 6195656  1
1982 Moolenaar WH, Yarden Y, de Laat SW, Schlessinger J. Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts. The Journal of Biological Chemistry. 257: 8502-6. PMID 6979542  1
1982 Schlessinger J, Schreiber AB, Lax I, Yashuv-Gan Y, Libermann TA, Hillman GM, Levi A, Yarden Y. Molecular steps in the action and regulation of epidermal growth factor: a cellular mitogen. Progress in Clinical and Biological Research. 91: 359-72. PMID 6292947  1
1982 Yarden Y, Schreiber AB, Schlessinger J. A nonmitogenic analogue of epidermal growth factor induces early responses mediated by epidermal growth factor. The Journal of Cell Biology. 92: 687-93. PMID 6282891  1
1981 Schreiber AB, Lax I, Yarden Y, Eshhar Z, Schlessinger J. Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor. Proceedings of the National Academy of Sciences of the United States of America. 78: 7535-9. PMID 6278478  1
1981 Zidovetzki R, Yarden Y, Schlessinger J, Jovin TM. Rotational diffusion of epidermal growth factor complexed to cell surface receptors reflects rapid microaggregation and endocytosis of occupied receptors. Proceedings of the National Academy of Sciences of the United States of America. 78: 6981-5. PMID 6273899  1
1981 Schreiber AB, Yarden Y, Schlessinger J. A non-mitogenic analogue of epidermal growth factor enhances the phosphorylation of endogenous membrane proteins. Biochemical and Biophysical Research Communications. 101: 517-23. PMID 6272761 DOI: 10.1016/0006-291X(81)91290-0  1
1981 Yarden Y, Gabbay M, Schlessinger J. Primary amines do not prevent the endocytosis of epidermal growth factor into 3T3 fibroblasts. Biochimica Et Biophysica Acta. 674: 188-203. PMID 6263349 DOI: 10.1016/0304-4165(81)90377-9  1
1977 Schlessinger J, Steinberg IZ. Heterogeneity in the circular polarization of protein fluorescence [proceedings]. Biophysical Journal. 19: 80-2. PMID 880328 DOI: 10.1016/S0006-3495(77)85569-0  1
1977 Wolf DE, Schlessinger J, Elson EL, Webb WW, Blumenthal R, Henkart P. Diffusion and patching of macromolecules on planar lipid bilayer membranes. Biochemistry. 16: 3476-83. PMID 560860  1
1977 Schlessinger J, Axelrod D, Koppel DE, Webb WW, Elson EL. Lateral transport of a lipid probe and labeled proteins on a cell membrane. Science (New York, N.Y.). 195: 307-9. PMID 556653  1
1977 Schlessinger J, Barak LS, Hammes GG, Yamada KM, Pastan I, Webb WW, Elson EL. Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components. Proceedings of the National Academy of Sciences of the United States of America. 74: 2909-13. PMID 331320 DOI: 10.1073/pnas.74.7.2909  1
1977 Givol D, Sharon J, Hochman J, Gavish M, Inbar D, Pecht I, Steinberg IZ, Schlessinger J. Folding, association, and interactions of domains in the antibody molecule. Cold Spring Harbor Symposia On Quantitative Biology. 41: 667-75. PMID 268251  1
1977 Schlessinger J, Elson EL, Webb WW, Yahara I, Rutishauser U, Edelman GM. Receptor diffusion on cell surfaces modulated by locally bound concanavalin A. Proceedings of the National Academy of Sciences of the United States of America. 74: 1110-4. PMID 265557  1
1976 Axelrod D, Ravdin P, Koppel DE, Schlessinger J, Webb WW, Elson EL, Podleski TR. Lateral motion of fluorescently labeled acetylcholine receptors in membranes of developing muscle fibers. Proceedings of the National Academy of Sciences of the United States of America. 73: 4594-8. PMID 1070010 DOI: 10.1073/pnas.73.12.4594  1
1976 Schlessinger J, Koppel DE, Axelrod D, Jacobson K, Webb WW, Elson EL. Lateral transport on cell membranes: mobility of concanavalin A receptors on myoblasts. Proceedings of the National Academy of Sciences of the United States of America. 73: 2409-13. PMID 1065895 DOI: 10.1073/pnas.73.7.2409  1
1976 Elson EL, Schlessinger J, Koppel DE, Axelrod D, Webb WW. Measurement of lateral transport on cell surfaces. Progress in Clinical and Biological Research. 9: 137-47. PMID 1030797  1
1976 Schlessinger J, Webb WW, Elson EL, Metzger H. Lateral motion and valence of Fc receptors on rat peritoneal mast cells. Nature. 264: 550-2. PMID 1004593 DOI: 10.1038/264550a0  1
1976 Koppel DE, Axelrod D, Schlessinger J, Elson EL, Webb WW. Dynamics of fluorescence marker concentration as a probe of mobility. Biophysical Journal. 16: 1315-29. PMID 974223 DOI: 10.1016/S0006-3495(76)85776-1  1
1976 Axelrod D, Koppel DE, Schlessinger J, Elson E, Webb WW. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics. Biophysical Journal. 16: 1055-69. PMID 786399 DOI: 10.1016/S0006-3495(76)85755-4  1
1975 Gafni A, Hardt H, Schlessinger J, Steinberg IZ. Circular polarization of fluorescence of chlorophyll in solution and in native structures. Biochimica Et Biophysica Acta. 387: 256-64. PMID 1125291 DOI: 10.1016/0005-2728(75)90108-5  1
1975 Schlessinger J, Steinberg IZ, Givol D, Hochman J. Subunit interaction in antibodies and antibody fragments studied by circular polarization of fluorescence. Febs Letters. 52: 231-5. PMID 1093870 DOI: 10.1016/0014-5793(75)80812-X  1
1975 Schlessinger J, Steinberg IZ, Givol D, Hochman J, Pecht I. Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 72: 2775-9. PMID 1058492 DOI: 10.1073/pnas.72.7.2775  1
1975 Licht A, Schlessinger J, Steinberg IZ, Pecht I. Proceedings: Heterogenity of antibody binding sites of inbred mice as revealed by circular polarization of fluorescence. Israel Journal of Medical Sciences. 11: 1393. PMID 767293  1
1975 Grinvald A, Schlessinger J, Pecht I, Steinberg IZ. Homogeneity and variability in the structure of azurin molecules studied by fluorescence decay and circular polarization. Biochemistry. 14: 1921-29. PMID 235970  1
1975 Schlessinger J, Roche RS, Steinberg IZ. A study of subtilisin types Novo and Carlsberg by circular polarization of fluorescence. Biochemistry. 14: 255-62. PMID 235273  1
1975 Schlessinger J, Steinberg IZ, Levitzki A. A comparative study of NAD+ binding sites in dehydrogenases by circular polarization of fluorescence. Journal of Molecular Biology. 91: 523-8. PMID 168387 DOI: 10.1016/0022-2836(75)90279-X  1
1974 Schlessinger J, Steinberg IZ, Pecht I. Antibody-hapten interactions: circular and linear polarization of the fluorescence of dansyl bound to anti-dansyl antibodies. Journal of Molecular Biology. 87: 725-40. PMID 4427374 DOI: 10.1016/0022-2836(74)90081-3  1
1972 Schlessinger J, Steinberg IZ. Circular polarization of fluorescence of probes bound to chymotrypsin. Change in asymmetric environment upon electronic excitation. Proceedings of the National Academy of Sciences of the United States of America. 69: 769-72. PMID 4501593  1
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