David B. Sykes, Ph.D. - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 

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Year Citation  Score
2023 Kfoury YS, Ji F, Jain E, Mazzola MC, Schiroli G, Papazian A, Mercier FE, Sykes DB, Kiem A, Randolph MA, Abdel-Wahab OI, Calvi LM, Sadreyev R, Scadden DT. The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression. Blood Advances. PMID 37450380 DOI: 10.1182/bloodadvances.2022008268  0.315
2023 Rhee C, Scadden EW, Wong LP, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee BK, Kim J, Nahrendorf M, Mansour M, Sykes DB, Sadreyev R, et al. Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors. Blood. PMID 37267513 DOI: 10.1182/blood.2023020257  0.311
2022 Wang H, He X, Zhang L, Dong H, Huang F, Xian J, Li M, Chen W, Lu X, Pathak KV, Huang W, Li Z, Zhang L, Nguyen LXT, Yang L, ... ... Sykes DB, et al. Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade. Blood. PMID 35439288 DOI: 10.1182/blood.2021015108  0.3
2021 Blanco MA, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, Jambhekar A, Cheloufi S, Meissner A, Hochedlinger K, Scadden DT, et al. Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports. 37: 109967. PMID 34758323 DOI: 10.1016/j.celrep.2021.109967  0.303
2020 van Gastel N, Spinelli JB, Sharda A, Schajnovitz A, Baryawno N, Rhee C, Oki T, Grace E, Soled HJ, Milosevic J, Sykes DB, Hsu PP, Vander Heiden MG, Vidoudez C, Trauger SA, et al. Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance. Cell Metabolism. PMID 32763164 DOI: 10.1016/J.Cmet.2020.07.009  0.365
2020 Yusuf R, Saez B, Sharda A, van Gastel N, Yu V, Baryawno N, Scadden EW, Acharya SS, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, et al. Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers. Blood. PMID 32458004 DOI: 10.1182/Blood.2019001808  0.358
2020 Negoro PE, Xu S, Dagher Z, Hopke A, Reedy JL, Feldman MB, Khan NS, Viens AL, Alexander NJ, Atallah NJ, Scherer AK, Dutko RA, Jeffery J, Kernien JF, Fites JS, ... ... Sykes DB, et al. Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Species. Mbio. 11. PMID 32398316 DOI: 10.1128/Mbio.02043-19  0.376
2020 Nguyen GT, Shaban L, Mack M, Swanson KD, Bunnell SC, Sykes DB, Mecsas J. SKAP2 is required for defense against infection and neutrophil respiratory burst. Elife. 9. PMID 32352382 DOI: 10.7554/Elife.56656  0.309
2020 Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, et al. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nature Communications. 11: 1406. PMID 32179749 DOI: 10.1038/S41467-020-15221-Z  0.407
2020 Lee S, Micalizzi D, Truesdell SS, Bukhari SIA, Boukhali M, Lombardi-Story J, Kato Y, Choo MK, Dey-Guha I, Ji F, Nicholson BT, Myers DT, Lee D, Mazzola MA, Raheja R, ... ... Sykes D, et al. A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells. Genome Biology. 21: 33. PMID 32039742 DOI: 10.1186/S13059-020-1936-4  0.354
2019 Christian S, Merz C, Evans L, Gradl S, Seidel H, Friberg A, Eheim A, Lejeune P, Brzezinka K, Zimmermann K, Ferrara S, Meyer H, Lesche R, Stoeckigt D, Bauser M, ... ... Sykes DB, et al. The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia. PMID 30940908 DOI: 10.1038/S41375-019-0461-5  0.382
2019 Kugadas A, Geddes-McAlister J, Guy E, DiGiandomenico A, Sykes DB, Mansour MK, Mirchev R, Gadjeva M. Frontline Science: Employing enzymatic treatment options for management of ocular biofilm-based infections. Journal of Leukocyte Biology. PMID 30690787 DOI: 10.1002/Jlb.4Hi0918-364Rr  0.304
2019 Sexauer AN, Do B, Sykes DB. Loss of FLT3 Sensitizes Myeloid Cells to Differentiation Via DHODH Inhibition Blood. 134: 2712-2712. DOI: 10.1182/Blood-2019-128910  0.443
2019 Kfoury Y, Ji F, Mazzola M, Sykes DB, Anthony A, Akiyama Y, Scherer A, Mercier F, Severe N, Saez B, Seidl J, Papazian A, Brouse T, Mansour MK, Ivanov P, et al. Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to Stress Blood. 134: 1207-1207. DOI: 10.1182/Blood-2019-124794  0.391
2019 Rhee CS, Scadden EW, Phillip CL, Lee B, Mistry M, Hoyer FF, Kato H, Mantica G, Kim J, Nahrendorf M, Mansour MK, Sykes DB, Scadden DT. Functionally Distinct Subsets of Monocytes in Mouse and Human Blood Blood. 134: 438-438. DOI: 10.1182/Blood-2019-124054  0.441
2019 Eheim A, Christian S, Meyer H, Stoeckigt D, Merz C, Zimmermann K, Bauser M, Haegebarth A, Ferrara S, Sykes DB, Scadden DT, Gradl S, Janzer A. Abstract 3597: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of diffuse large B-cell lymphoma (DLBCL) Cancer Research. 79: 3597-3597. DOI: 10.1158/1538-7445.Am2019-3597  0.364
2019 Gradl SN, Mueller T, Ferrara S, Sheikh SE, Janzer A, Zhou H, Friberg A, Guenther J, Schaefer M, Stellfeld T, Eis K, Kroeber M, Nguyen D, Merz C, Niehues M, ... ... Sykes DB, et al. Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies Cancer Research. 79: 2-2. DOI: 10.1158/1538-7445.Am2019-2  0.307
2018 Lin B, Srikanth P, Castle AC, Nigwekar S, Malhotra R, Galloway JL, Sykes DB, Rajagopal J. Modulating Cell Fate as a Therapeutic Strategy. Cell Stem Cell. PMID 29910150 DOI: 10.1016/J.Stem.2018.05.009  0.348
2018 Sykes DB, Schroyens W. Complete Responses in the TEMPI Syndrome after Treatment with Daratumumab. The New England Journal of Medicine. 378: 2240-2242. PMID 29874534 DOI: 10.1056/Nejmc1804415  0.316
2018 Dagher Z, Xu S, Negoro PE, Khan NS, Feldman MB, Reedy JL, Tam JM, Sykes DB, Mansour MK. Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of in Macrophages. Frontiers in Immunology. 9: 1058. PMID 29868018 DOI: 10.3389/Fimmu.2018.01058  0.334
2018 Fites JS, Gui M, Kernien JF, Negoro P, Dagher Z, Sykes DB, Nett JE, Mansour MK, Klein BS. An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections. Plos Pathogens. 14: e1007073. PMID 29782541 DOI: 10.1371/Journal.Ppat.1007073  0.339
2018 Kfoury Y, Jain E, Myers JR, Ji F, Sykes DB, Mercier F, Papazian A, Le C, Randolph MA, Steensma DP, Abdel-Wahab OI, Calvi LM, Sadreyev RI, Becker MW, Scadden DT. Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells Blood. 132: 938-938. DOI: 10.1182/Blood-2018-99-115242  0.369
2018 Hsu PP, Kfoury Y, Aziz N, Elkhoury J, Hallgren B, Scadden DT, Vander Heiden M, Sykes DB. DHODH Inhibitors in the Treatment of Acute Myeloid Leukemia: Defining the Mechanism of Action and the Basis of the Metabolic Therapeutic Window Blood. 132: 2716-2716. DOI: 10.1182/Blood-2018-99-113387  0.412
2018 Janzer A, Gradl S, Christian S, Zimmermann K, Merz C, Meyer H, Stellfeld T, Guenther J, Stoeckigt D, Seidel H, Lejeune P, Bruening M, Eheim A, Mueller T, Lesche R, ... ... Sykes D, et al. Abstract DDT02-04: BAY 2402234: A novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ddt02-04  0.399
2018 Mercier F, Shi J, Sykes D, Oki T, Miller E, Vasic R, Zhu A, Severe N, Schajnovitz A, Man C, Kfoury Y, Lee D, Doench J, Hide W, Michor F, et al. In Vivo Profiling of Leukemic Stem Cell Fitness Identifies Therapeutically Actionable Determinants of Growth Experimental Hematology. 64: S86. DOI: 10.1016/J.Exphem.2018.06.095  0.356
2017 Lee PY, Sykes DB, Ameri S, Kalaitzidis D, Charles JF, Nelson-Maney N, Wei K, Cunin P, Morris A, Cardona AE, Root DE, Scadden DT, Nigrovic PA. The metabolic regulator mTORC1 controls terminal myeloid differentiation. Science Immunology. 2. PMID 28763796 DOI: 10.1126/Sciimmunol.Aam6641  0.453
2017 Kalaitzidis D, Lee D, Efeyan A, Kfoury Y, Nayyar N, Sykes DB, Mercier FE, Papazian A, Baryawno N, Victora GD, Neuberg D, Sabatini DM, Scadden DT. Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells. The Journal of Clinical Investigation. PMID 28319048 DOI: 10.1172/Jci89452  0.394
2017 Mercier F, Shi J, Sykes DB, Miller E, Oki T, Man C, Yan X, Kfoury Y, Lee D, Doench JG, Michor F, Scadden DT. A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing Blood. 130: 2493-2493. DOI: 10.1182/Blood.V130.Suppl_1.2493.2493  0.41
2017 Janzer A, Sykes D, Gradl S, Ferrara S, Christian S, Merz C, Seidel H, Bernthaler A, Lesche R, Wawer M, Scadden DT. Abstract 3086: Inhibitors of the enzyme dihydroorotate dehydrogenase, overcome the differentiation blockade in acute myeloid leukemia Cancer Research. 77: 3086-3086. DOI: 10.1158/1538-7445.Am2017-3086  0.413
2016 Lewis TA, Sykes DB, Law JM, Muñoz B, Rustiguel JK, Nonato MC, Scadden DT, Schreiber SL. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. Acs Medicinal Chemistry Letters. 7: 1112-1117. PMID 27994748 DOI: 10.1021/Acsmedchemlett.6B00316  0.401
2016 Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, ... ... Sykes DB, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nature Medicine. PMID 27941791 DOI: 10.1038/Nm.4242  0.331
2016 Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. PMID 27641501 DOI: 10.1016/J.Cell.2016.08.057  0.442
2016 Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nature Biotechnology. PMID 27272386 DOI: 10.1038/Nbt.3584  0.372
2016 Mercier FE, Sykes DB, Scadden DT. Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1(STEM) Mouse. Stem Cell Reports. PMID 27185283 DOI: 10.1016/J.Stemcr.2016.04.010  0.314
2016 Lee D, Wang YH, Kalaitzidis D, Ramachandran J, Eda H, Sykes DB, Raje N, Scadden DT. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. The Journal of Clinical Investigation. PMID 26927669 DOI: 10.1172/Jci84620  0.353
2016 Sykes DB, Kfoury YS, Mercier F, Wawer M, Schajnovitz A, Meyer H, Pierce KA, Stoeckigt D, Clish CB, Clemons PA, Janzer A, Scadden DT. Inhibition of the Enzyme Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Blood. 128: 1656-1656. DOI: 10.1182/Blood.V128.22.1656.1656  0.442
2015 Chen E, Ahn JS, Sykes DB, Breyfogle LJ, Godfrey AL, Nangalia J, Ko A, DeAngelo DJ, Green AR, Mullally A. RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability. Cell Reports. 13: 2345-52. PMID 26686625 DOI: 10.1016/J.Celrep.2015.11.037  0.306
2015 Kenderian SS, Rosado FG, Sykes DB, Hoyer JD, Lacy MQ. Long-term complete clinical and hematological responses of the TEMPI syndrome after autologous stem cell transplantation. Leukemia. PMID 26500143 DOI: 10.1038/Leu.2015.298  0.315
2015 Yoon KW, Byun S, Kwon E, Hwang SY, Chu K, Hiraki M, Jo SH, Weins A, Hakroush S, Cebulla A, Sykes DB, Greka A, Mundel P, Fisher DE, Mandinova A, et al. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. Science (New York, N.Y.). 349. PMID 26228159 DOI: 10.1126/Science.1261669  0.355
2015 Belizaire R, Sykes DB, Chen YB, Spitzer TR, Makar RS. Difficulties in hematopoietic progenitor cell collection from a patient with TEMPI syndrome and severe iatrogenic iron deficiency. Transfusion. PMID 25911963 DOI: 10.1111/Trf.13125  0.355
2015 Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, et al. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell Reports. PMID 25660025 DOI: 10.1016/J.Celrep.2015.01.017  0.36
2015 Rosado FG, Oliveira JL, Sohani AR, Schroyens W, Sykes DB, Kenderian SS, Lacy MQ, Kyle RA, Hoyer JD. Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 367-72. PMID 25216227 DOI: 10.1038/Modpathol.2014.117  0.335
2015 Perez-Ladaga A, Xie H, Orkin SH, Sykes DB, Ebert BL, Bejar R. Neutrophils Derived from Ezh2 -/- Progenitor Cells Demonstrate Aberrant Erythroid Lineage Gene Expression Blood. 126: 4112-4112. DOI: 10.1182/Blood.V126.23.4112.4112  0.444
2015 Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Mansour MK, Scadden DT. Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation Blood. 126: 32-32. DOI: 10.1182/Blood.V126.23.32.32  0.332
2014 Mercier F, Shi J, Sykes D, Kfoury YS, Yusuf RZ, Miller E, Vasic R, Zhu A, Michor F, Hide W, Scadden DT. Identification of a Gene Expression Signature Characterizing Clonal Fitness and Dominance in Vivo in a Murine Model of MLL-AF9 Leukemia Blood. 124: 2383-2383. DOI: 10.1182/Blood.V124.21.2383.2383  0.42
2014 Sykes D, Kfoury Y, Blanco A, Scadden D. Phenotypic screening identifies prostacyclin agonists as differentiation agents in the treatment of acute myeloid leukemia Experimental Hematology. 42: S25. DOI: 10.1016/J.Exphem.2014.07.085  0.463
2013 Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin. Embo Molecular Medicine. 5: 430-40. PMID 23364955 DOI: 10.1002/Emmm.201201606  0.391
2013 Palchaudhuri R, Ang K, Saez B, Sykes DB, Verdine GL, Scadden DT. Differentiation Induction In Acute Myeloid Leukemia Using Site-Specific DNA-Targeting Blood. 122: 3940-3940. DOI: 10.1182/Blood.V122.21.3940.3940  0.409
2013 Geng H, Hurtz C, Chen Z, Chen W, Ballabio E, Xiao G, Kweon S, Nahar R, Sojaee S, Chan LN, Masouleh BK, Sykes DB, Melnick A, Roeder R, Milne T, et al. Targeting Pre-B Cell Receptor and BCL6 In TCF3-PBX1 B-Lineage Acute Lymphoblastic Leukemia Blood. 122: 349-349. DOI: 10.1182/Blood.V122.21.349.349  0.376
2013 Perez-Ladaga A, Caughey B, Xie H, Orkin SH, Sykes DB, Ebert BL, Bejar R. Functional Defects In Neutrophils Derived From Ezh2 Null Mice Blood. 122: 1556-1556. DOI: 10.1182/Blood.V122.21.1556.1556  0.44
2013 Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. Corrigendum to SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin [EMBO Mol Med] DOI:10.1002/emmm.201201606 Embo Molecular Medicine. 5: 482. DOI: 10.1002/Emmm.201390004  0.351
2012 Park D, Sykes DB, Scadden DT. The hematopoietic stem cell niche. Frontiers in Bioscience (Landmark Edition). 17: 30-9. PMID 22201730 DOI: 10.2741/3913  0.389
2012 Schroyens WA, O'Connell CL, Lacy MQ, Attar EC, Raje N, Somer BG, Rosado FG, Hoyer J, Feinstein DI, Sykes DB. TEMPI: A Reversible Syndrome Following Treatment with Bortezomib Blood. 120: 986-986. DOI: 10.1182/Blood.V120.21.986.986  0.32
2012 Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Carmody L, Yusuf RZ, Sykes DB, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Cheah J, et al. Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma Blood. 120: 571-571. DOI: 10.1182/Blood.V120.21.571.571  0.37
2012 Sykes DB, Haynes MK, Tolliday N, Waller A, Cobert JM, Szekely BA, Hasaka TP, Sklar L, Zon LI, Scadden DT. Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia Blood. 120: 3513-3513. DOI: 10.1182/Blood.V120.21.3513.3513  0.482
2012 Yusuf RZ, Acharya SS, Yu VW, Saez B, Cobert JM, Doench J, Bullinger L, S'aulis D, Lee D, Palchaudhuri R, Uzosike AC, Duvet M, Logan DJ, Das S, Cook CM, ... ... Sykes DB, et al. Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells Blood. 120: 208-208. DOI: 10.1182/Blood.V120.21.208.208  0.414
2011 Sykes DB, Schroyens WA, O'Connell CL, Feinstein DI, Bazari H, Dahl DM, Colvin RB, Paelinck BP, Uppot RN, Beeck BOd, Boswell W, Raje NS, Harris NL, Attar EC. The TEMPI Syndrome: Telangiectasias, Elevated Erythropoietin and Erythrocytosis, Monoclonal Gammopathy, Perinephric Fluid Collections, and Intrapulmonary Shunting Blood. 118: 1037-1037. DOI: 10.1182/Blood.V118.21.1037.1037  0.317
2009 Scheele JS, Kolanczyk M, Gantert M, Zemojtel T, Dorn A, Sykes DB, Sykes DP, Möbest DC, Kamps MP, Räpple D, Duchniewicz M. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1. Leukemia & Lymphoma. 50: 816-28. PMID 19399691 DOI: 10.1080/10428190902836107  0.618
2007 Odegaard JI, Vats D, Zhang L, Ricardo-Gonzalez R, Smith KL, Sykes DB, Kamps MP, Chawla A. Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages. Journal of Leukocyte Biology. 81: 711-9. PMID 17158607 DOI: 10.1189/Jlb.0906590  0.669
2006 Wang GG, Calvo KR, Pasillas MP, Sykes DB, Häcker H, Kamps MP. Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8. Nature Methods. 3: 287-93. PMID 16554834 DOI: 10.1038/Nmeth865  0.743
2004 Sykes DB, Kamps MP. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice. Molecular and Cellular Biology. 24: 1256-69. PMID 14729970 DOI: 10.1128/Mcb.24.3.1256-1269.2004  0.628
2003 Sykes DB, Scheele J, Pasillas M, Kamps MP. Transcriptional profiling during the early differentiation of granulocyte and monocyte progenitors controlled by conditional versions of the E2a-Pbx1 oncoprotein. Leukemia & Lymphoma. 44: 1187-99. PMID 12916872 DOI: 10.1080/1042819031000090273  0.66
2003 Sykes DB, Kamps MP. Estrogen-regulated conditional oncoproteins: tools to address open questions in normal myeloid cell function, normal myeloid differentiation, and the genetic basis of differentiation arrest in myeloid leukemia. Leukemia & Lymphoma. 44: 1131-9. PMID 12916864 DOI: 10.1080/1042819031000063444  0.682
2002 Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. The Journal of Biological Chemistry. 277: 42821-9. PMID 12215441 DOI: 10.1074/Jbc.M205873200  0.384
2002 Calvo KR, Sykes DB, Pasillas MP, Kamps MP. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1. Oncogene. 21: 4247-56. PMID 12082612 DOI: 10.1038/Sj.Onc.1205516  0.734
2002 Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 109: 169-80. PMID 12007404 DOI: 10.1016/S0092-8674(02)00714-6  0.644
2001 Calvo KR, Knoepfler PS, Sykes DB, Pasillas MP, Kamps MP. Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 98: 13120-5. PMID 11687616 DOI: 10.1073/Pnas.231115398  0.733
2001 Sykes DB, Kamps MP. Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be arrested by other leukemic oncoproteins. Blood. 98: 2308-18. PMID 11588024 DOI: 10.1182/Blood.V98.8.2308  0.682
2001 Knoepfler PS, Sykes DB, Pasillas M, Kamps MP. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation. Oncogene. 20: 5440-8. PMID 11571641 DOI: 10.1038/Sj.Onc.1204710  0.669
2000 Calvo KR, Sykes DB, Pasillas M, Kamps MP. Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Molecular and Cellular Biology. 20: 3274-85. PMID 10757811 DOI: 10.1128/Mcb.20.9.3274-3285.2000  0.727
1997 Parney IF, Petruk KC, Zhang C, Farr-Jones M, Sykes DB, Chang LJ. Granulocyte-macrophage colony-stimulating factor and B7-2 combination immunogene therapy in an allogeneic Hu-PBL-SCID/beige mouse-human glioblastoma multiforme model. Human Gene Therapy. 8: 1073-85. PMID 9189765 DOI: 10.1089/Hum.1997.8.9-1073  0.352
Low-probability matches (unlikely to be authored by this person)
2016 Sykes D, Martinelli M, Maxcy K, Carver A, Negoro P, Dagher-Mansour Z, Scadden D, Mansour M. The transfusion of conditionally-immortalized granulocyte macrophage progenitors into neutropenic mice protects in a model of lethal fungal infection Experimental Hematology. 44: S101. DOI: 10.1016/J.Exphem.2016.06.220  0.297
2021 Zee BM, Poels KE, Yao CH, Kawabata KC, Wu G, Duy C, Jacobus WD, Senior E, Endress JE, Jambhekar A, Lovitch SB, Ma J, Dhall A, Harris IS, Blanco MA, ... Sykes DB, et al. Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia. Iscience. 24: 102651. PMID 34151238 DOI: 10.1016/j.isci.2021.102651  0.292
2021 Yan F, Li J, Milosevic J, Petroni R, Liu S, Shi Z, Yuan S, Reynaga JM, Qi Y, Rico J, Yu S, Liu Y, Rokudai S, Palmisiano N, Meyer SE, ... ... Sykes DB, et al. KAT6A and ENL form an epigenetic transcriptional control module to drive critical leukemogenic gene expression programs. Cancer Discovery. PMID 34853079 DOI: 10.1158/2159-8290.CD-20-1459  0.291
2020 Sykes DB, O'Connell C, Schroyens W. The TEMPI syndrome. Blood. 135: 1199-1203. PMID 32108223 DOI: 10.1182/Blood.2019004216  0.284
2020 Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, et al. Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney. The Journal of Clinical Investigation. PMID 32065590 DOI: 10.1172/Jci131190  0.284
2015 Gupta S, Fenves A, Nance ST, Sykes DB, Dzik WS. Hyperhemolysis syndrome in a patient without a hemoglobinopathy, unresponsive to treatment with eculizumab. Transfusion. 55: 623-8. PMID 25257194 DOI: 10.1111/Trf.12876  0.282
2022 Murthy S, Baruah S, Bowen JL, Keck K, Wagner BA, Buettner GR, Sykes DB, Klesney-Tait J. TREM-1 is required for enhanced OpZ-induced superoxide generation following priming. Journal of Leukocyte Biology. PMID 35075692 DOI: 10.1002/JLB.3A0421-212R  0.28
2020 Hirz T, Mei S, Kfoury Y, Wu C, Dahl DM, Saylor P, Kharchenko P, Baryawno N, Sykes D. Abstract 3446: High-resolution mapping of human prostate tumors- guiding better risk stratification and therapeutic approaches Cancer Research. 80: 3446-3446. DOI: 10.1158/1538-7445.Am2020-3446  0.279
2017 Sun L, Sykes DB. Acquired haemophilia A with a recalcitrant high-titre factor VIII inhibitor in the setting of interstitial lung disease. Bmj Case Reports. 2017. PMID 28756381 DOI: 10.1136/Bcr-2017-220932  0.275
2013 Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM. Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes. The Journal of Biological Chemistry. 288: 16043-54. PMID 23609446 DOI: 10.1074/Jbc.M113.473223  0.272
2022 Kugler E, Madiwale S, Yong D, Birger Y, Thoms JA, Sykes DB, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, Raught B, Liu Q, Milyavsky M, et al. AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML. Clinical Lymphoma, Myeloma & Leukemia. S215-S216. PMID 36163769 DOI: 10.1016/S2152-2650(22)01225-3  0.271
2018 Sykes DB. The emergence of dihydroorotate dehydrogenase (DHODH) as a therapeutic target in acute myeloid leukemia. Expert Opinion On Therapeutic Targets. 1-6. PMID 30318938 DOI: 10.1080/14728222.2018.1536748  0.27
2001 Slupsky CM, Sykes DB, Gay GL, Sykes BD. The HoxB1 hexapeptide is a prefolded domain: implications for the Pbx1/Hox interaction. Protein Science : a Publication of the Protein Society. 10: 1244-53. PMID 11369863 DOI: 10.1110/Ps.50901  0.268
2022 Sykes DB, Martinelli MM, Negoro P, Xu S, Maxcy K, Timmer K, Viens AL, Alexander NJ, Atallah J, Snarr BD, Baistrocchi SR, Atallah NJ, Hopke A, Scherer A, Rosales I, et al. Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections. Journal of Leukocyte Biology. PMID 35355310 DOI: 10.1002/JLB.4HI1221-722R  0.266
2015 Lang D, Mead JS, Sykes DB. Hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma. Journal of General Internal Medicine. 30: 692-6. PMID 25583570 DOI: 10.1007/S11606-014-3161-X  0.264
2013 Singh H, Lane AA, Correll M, Przychodzen B, Sykes DB, Stone RM, Ballen KK, Amrein PC, Maciejewski J, Attar EC. Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies. Blood Cancer Journal. 3: e117. PMID 23708642 DOI: 10.1038/Bcj.2013.16  0.263
2022 Rosenberg JM, Peters JM, Hughes T, Lareau CA, Ludwig LS, Massoth LR, Austin-Tse C, Rehm HL, Bryson B, Chen YB, Regev A, Shalek AK, Fortune SM, Sykes DB. JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia. Med (New York, N.Y.). 3: 42-57.e5. PMID 35590143 DOI: 10.1016/j.medj.2021.12.003  0.263
2020 Al-Samkari H, Rosovsky RP, Karp Leaf RS, Smith DB, Goodarzi K, Fogerty AE, Sykes DB, Kuter DJ. A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia. Blood Advances. 4: 9-18. PMID 31891657 DOI: 10.1182/Bloodadvances.2019000868  0.263
2015 Wu L, Walas S, Leung W, Sykes DB, Wu J, Lo EH, Lok J. Neuregulin1-β decreases IL-1β-induced neutrophil adhesion to human brain microvascular endothelial cells. Translational Stroke Research. 6: 116-24. PMID 24863743 DOI: 10.1007/S12975-014-0347-9  0.263
2014 Khan J, Sykes DB. Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting. Bmc Hematology. 14: 11. PMID 25143825 DOI: 10.1186/2052-1839-14-11  0.258
2024 Mei S, Alchahin AM, Embaie BT, Gavriliuc IM, Verhoeven BM, Zhao T, Li X, Jeffries NE, Pepich A, Sarkar H, Olsen TK, Wickström M, Stenman J, Reina-Bedoya O, Kharchenko PV, ... ... Sykes DB, et al. Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic signature. Jci Insight. PMID 38358826 DOI: 10.1172/jci.insight.173337  0.258
2019 Mann M, Kreuzbauer T, Sykes DB. A man with polycythemia vera, myelodysplastic syndrome and acquired microcytosis. Bmj Case Reports. 12. PMID 31413051 DOI: 10.1136/Bcr-2019-229695  0.255
2019 Sohn J, Brouse T, Aziz N, Sykes DB. What Links Neutropenia to Immature Cardiolipin in Patients with Barth Syndrome (tafazzin-deficiency)? Blood. 134: 3579-3579. DOI: 10.1182/Blood-2019-123680  0.254
2011 Sykes DB, Schroyens W, O'Connell C. The TEMPI syndrome--a novel multisystem disease. The New England Journal of Medicine. 365: 475-7. PMID 21812700 DOI: 10.1056/Nejmc1106670  0.252
2022 Colligan SH, Amitrano AM, Zollo RA, Peresie J, Kramer ED, Morreale B, Barbi J, Singh PK, Yu H, Wang J, Opyrchal M, Sykes DB, Nemeth MJ, Abrams SI. Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression. The Journal of Clinical Investigation. 132. PMID 36453551 DOI: 10.1172/JCI158661  0.251
1987 Wilson R, Pitt T, Taylor G, Watson D, MacDermot J, Sykes D, Roberts D, Cole P. Pyocyanin and 1-hydroxyphenazine produced by Pseudomonas aeruginosa inhibit the beating of human respiratory cilia in vitro. Journal of Clinical Investigation. 79: 221-229. PMID 3098783 DOI: 10.1172/Jci112787  0.25
2024 Bonilla G, Morris A, Kundu S, Ducasse A, Jeffries NE, Chetal K, Yvanovich EE, Barghout R, Scadden D, Mansour MK, Kingston RE, Sykes DB, Mercier FE, Sadreyev RI. Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators. Biorxiv : the Preprint Server For Biology. PMID 38496490 DOI: 10.1101/2024.02.29.582846  0.249
2012 Schroyens W, O'Connell C, Sykes DB. Complete and partial responses of the TEMPI syndrome to bortezomib. The New England Journal of Medicine. 367: 778-80. PMID 22913703 DOI: 10.1056/Nejmc1205806  0.246
2023 Kugler E, Madiwale S, Yong D, Thoms JAI, Birger Y, Sykes DB, Schmoellerl J, Drakul A, Priebe V, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, et al. The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG. Nature Communications. 14: 5871. PMID 37735473 DOI: 10.1038/s41467-023-41067-2  0.244
2018 Garza-Mayers AC, Shah R, Sykes DB, Nigwekar SU, Kroshinsky D. The Successful Use of Apixaban in Dialysis Patients with Calciphylaxis Who Require Anticoagulation: A Retrospective Analysis. American Journal of Nephrology. 48: 168-171. PMID 30176675 DOI: 10.1159/000491881  0.244
2022 Sohn J, Milosevic J, Brouse T, Aziz N, Elkhoury J, Wang S, Hauschild A, van Gastel N, Cetinbas M, Tufa SF, Keene DR, Sadreyev R, Pu WT, Sykes DB. A new murine model of Barth Syndrome neutropenia links TAFAZZIN deficiency to increased ER stress induced apoptosis. Blood Advances. PMID 34979560 DOI: 10.1182/bloodadvances.2021005720  0.243
2022 Franklin R, Guo Y, He S, Chen M, Ji F, Zhou X, Frankhouser D, Do BT, Chiem C, Jang M, Blanco MA, Vander Heiden MG, Rockne RC, Ninova M, Sykes DB, et al. Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity. Nature Communications. 13: 2350. PMID 35487911 DOI: 10.1038/s41467-022-29730-6  0.242
2017 Mercier F, Shi J, Sykes D, Oki T, Miller E, Doench J, Michor F, Scadden D. A genome-wide, in vivo dropout CRISPR screen in acute myeloid leukemia Experimental Hematology. 53: S78-S79. DOI: 10.1016/J.Exphem.2017.06.169  0.24
2016 Sykes D, Dagher Z, Scadden D, Vyas J, Mansour M. A Novel System for the Study of Neutrophil-Fungal Interactions Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.1756  0.238
2018 Xu S, Feliu M, Lord AK, Lukason DP, Negoro PE, Khan NS, Dagher Z, Feldman MB, Reedy JL, Steiger SN, Tam JM, Soukas AA, Sykes DB, Mansour MK. Biguanides enhance antifungal activity against Candida glabrata. Virulence. PMID 29962263 DOI: 10.1080/21505594.2018.1475798  0.236
2018 Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Winau F, Hoggatt J, Saez B, Mansour MK, Sykes D, Scadden D, Rossi D. Immune Sparing Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins Biology of Blood and Marrow Transplantation. 24: S60-S61. DOI: 10.1016/J.Bbmt.2017.12.633  0.231
2020 Jan M, Grinshpun DE, Villalba JA, Dal Cin P, Sykes DB, Iafrate AJ, Ebert BL, Hobbs GS, Nardi V. A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia. Blood Advances. 4: 445-448. PMID 31999327 DOI: 10.1182/Bloodadvances.2019001182  0.229
2020 Nguyen GT, Shaban L, Mack M, Swanson KD, Bunnell SC, Sykes DB, Mecsas J. Author response: SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst Elife. DOI: 10.7554/Elife.56656.Sa2  0.225
2019 Ameri AH, Curtis BR, Sykes DB. Immune neutropenia mediated by micafungin. American Journal of Hematology. PMID 30945326 DOI: 10.1002/Ajh.25483  0.22
2023 Mullen NJ, Shukla SK, Thakur R, Kollala SS, Wang D, Chaika N, LaBreck DA, Mallareddy JR, Price DH, Natarajan A, Mehla K, Sykes DB, Hollingsworth MA, Singh PK. DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation. Biorxiv : the Preprint Server For Biology. PMID 37066260 DOI: 10.1101/2023.04.03.535399  0.219
2021 Kfoury YS, Ji F, Mazzola M, Sykes DB, Scherer AK, Anselmo A, Akiyama Y, Mercier F, Severe N, Kokkaliaris KD, Zhao T, Brouse T, Saez B, Seidl J, Papazian A, et al. tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche. Cell Stem Cell. PMID 34551362 DOI: 10.1016/j.stem.2021.08.014  0.218
2020 Sykes DB, Zhang EW, Karp Leaf RS, Nardi V, Turbett SE. Case 10-2020: An 83-Year-Old Man with Pancytopenia and Acute Renal Failure. The New England Journal of Medicine. 382: 1258-1266. PMID 32212524 DOI: 10.1056/Nejmcpc1916250  0.214
2019 Sykes DB. Insights From a Patient With Lung Cancer-Party Therapy Is Way Better Than Chemotherapy. Jama Oncology. PMID 31513260 DOI: 10.1001/Jamaoncol.2019.2591  0.212
1991 Mulkerrin E, Penney MD, Donovan K, Hampton D, Arnold J, Sykes D. Changes in AVP following aggressive diuretic therapy of severe congestive cardiac failure in elderly patients. Postgraduate Medical Journal. 67: 1085-1085. PMID 1800973 DOI: 10.1136/Pgmj.67.794.1085  0.212
2023 Sexauer AN, Alexe G, Gustafsson K, Zanetakos E, Milosevic J, Ayres ML, Gandhi V, Pikman Y, Stegmaier K, Sykes DB. DHODH: A promising target in the treatment of T-Acute Lymphoblastic Leukemia. Blood Advances. PMID 37648673 DOI: 10.1182/bloodadvances.2023010337  0.212
1990 Sykes D, Dewar R, Mohanaruban K, Donovan K, Nicklason F, Thomas DM, Fisher D. Measuring blood pressure in the elderly: does atrial fibrillation increase observer variability? Bmj. 300: 162-163. PMID 2105795 DOI: 10.1136/Bmj.300.6718.162  0.211
2022 Ko J, Wilkovitsch M, Oh J, Kohler RH, Bolli E, Pittet MJ, Vinegoni C, Sykes DB, Mikula H, Weissleder R, Carlson JCT. Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nature Biotechnology. PMID 35654978 DOI: 10.1038/s41587-022-01339-6  0.211
1992 Dewar R, Sykes D, Mulkerrin E, Nicklason F, Thomas D, Seymour R. The effect of hemiplegia on blood pressure measurement in the elderly. Postgraduate Medical Journal. 68: 888-91. PMID 1494509 DOI: 10.1136/Pgmj.68.805.888  0.21
2023 Timmer KD, Floyd DJ, Scherer AK, Crossen AJ, Atallah J, Viens AL, Sykes DB, Mansour MK. Multiparametric Profiling of Neutrophil Function via a High-Throughput Flow Cytometry-Based Assay. Cells. 12. PMID 36899878 DOI: 10.3390/cells12050743  0.208
2024 Maneix L, Iakova P, Lee CG, Moree SE, Lu X, Datar GK, Hill CT, Spooner E, King JCK, Sykes DB, Saez B, Di Stefano B, Chen X, Krause DS, Sahin E, et al. Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing. Nature Cell Biology. PMID 38553595 DOI: 10.1038/s41556-024-01387-x  0.206
2017 Sykes DB, Rosovsky RP, Singhal AB, Gonzalez RG, Moy AP. Case 40-2017. A 32-Year-Old Woman with Headache, Abdominal Pain, Anemia, and Thrombocytopenia. The New England Journal of Medicine. 377: 2581-2590. PMID 29281575 DOI: 10.1056/Nejmcpc1710566  0.202
2022 Haase C, Gustafsson K, Mei S, Yeh SC, Richter D, Milosevic J, Turcotte R, Kharchenko PV, Sykes DB, Scadden DT, Lin CP. Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging. Nature Methods. 19: 1622-1633. PMID 36424441 DOI: 10.1038/s41592-022-01673-2  0.202
2014 Mercier F, Shi J, Sykes D, Kfoury Y, Scadden D. Declined Presentation Experimental Hematology. 42: S50. DOI: 10.1016/J.Exphem.2014.07.189  0.201
1985 Wilson R, Sykes D, Currie D, Cole P. Multiple respiratory tract stenoses associated with mucociliary dysfunction. The Lancet. 326: 950. PMID 2865448 DOI: 10.1016/S0140-6736(85)90883-9  0.2
2022 Olsen TK, Dyberg C, Embaie BT, Alchahin AM, Milosevic J, Ding J, Otte J, Tümmler C, Hed Myrberg I, Westerhout EM, Koster J, Versteeg R, Ding HF, Kogner P, Johnsen JI, ... Sykes DB, et al. DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma. Jci Insight. PMID 35943801 DOI: 10.1172/jci.insight.153836  0.199
2022 Nappi D, Tauber M, Sykes D. Coexistence of TEMPI syndrome and leukocytoclastic vasculitis successfully treated with autologous stem cell transplantation. Ejhaem. 3: 1385-1387. PMID 36467823 DOI: 10.1002/jha2.561  0.198
2023 Chaudagar K, Rameshbabu S, Mei S, Hirz T, Hu YM, Argulian A, Labadie B, Desai K, Grimaldo S, Kahramangil D, Nair R, DSouza S, Zhou D, Li M, Doughan F, ... ... Sykes DB, et al. Androgen blockade primes NLRP3 in macrophages to induce tumor phagocytosis. Biorxiv : the Preprint Server For Biology. PMID 37904975 DOI: 10.1101/2023.09.15.557996  0.198
2022 Viens AL, Timmer KD, Alexander NJ, Barghout R, Milosevic J, Hopke A, Atallah NJ, Scherer AK, Sykes DB, Irimia D, Mansour MK. TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils. Journal of Immunology (Baltimore, Md. : 1950). PMID 35277418 DOI: 10.4049/jimmunol.2100599  0.197
2022 Boribong BP, LaSalle TJ, Bartsch YC, Ellett F, Loiselle ME, Davis JP, Gonye ALK, Sykes DB, Hajizadeh S, Kreuzer J, Pillai S, Haas W, Edlow AG, Fasano A, Alter G, et al. Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children. Cell Reports. Medicine. 100848. PMID 36476388 DOI: 10.1016/j.xcrm.2022.100848  0.195
2022 Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P, Chang MH, Wactor A, Wauford BM, Todd MJC, Wei K, ... ... Sykes DB, et al. mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nature Communications. 13: 6915. PMID 36443301 DOI: 10.1038/s41467-022-34480-6  0.195
1990 Sykes D, Donovan K, Dewar R, Nicklason F, Mohanaruban K, Thomas D, Fisher D. Measuring blood pressure in the elderly: Authors' reply Bmj. 300: 538-538. DOI: 10.1136/Bmj.300.6723.538-C  0.194
2022 Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, et al. Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical Science. 13: 5539-5545. PMID 35694350 DOI: 10.1039/d1sc06659e  0.193
1990 Sykes D, Mohanaruban K, Dewar R, Nicklason F, Donovan K, Fisher D. Measurement of Blood Pressure in the Elderly with Atrial Fibrillation: Is there Greater Observer Variability? Age and Ageing. 19. DOI: 10.1093/Ageing/19.Suppl_2.P10-A  0.192
1992 Mulkerrin E, Nicklason F, Sykes D, Dewar R, Bayer A, Finucane P. Assessment of Cognitive Impairment in Patients Being Discharged from Geriatric Wards Age and Ageing. 21. DOI: 10.1093/Ageing/21.Suppl_1.P15-C  0.189
2022 Alchahin AM, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, Wu CL, Subtelny AO, Wu S, Scadden DT, Shin JH, Saylor PJ, Sykes DB, Kharchenko PV, Baryawno N. A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma. Nature Communications. 13: 5747. PMID 36180422 DOI: 10.1038/s41467-022-33375-w  0.188
1992 Mulkerrin EC, Hampton D, Penney M, Brain A, Williams J, Sykes D, Woodhouse KW. Renal Effects of Low Dose Atrial Natriuretic Peptide (ANP) Infusion in Young and Elderly Volunteers Age and Ageing. 21. DOI: 10.1093/Ageing/21.Suppl_2.P16-C  0.183
1993 Mulkerrin E, Brain A, Hampton D, Sykes D, Penney, Woodhouse K. Plasma Arginine Vasopressin Levels During Atrial Natriuretic Peptide Infusion in the Young and Elderly Age and Ageing. 22. DOI: 10.1093/Ageing/22.Suppl_2.P14-A  0.183
2024 Mei S, Alchahin AM, Tsea I, Kfoury Y, Hirz T, Jeffries NE, Zhao T, Xu Y, Zhang H, Sarkar H, Wu S, Subtelny AO, Johnsen JI, Zhang Y, Salari K, ... ... Sykes DB, et al. Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions. Genome Medicine. 16: 1. PMID 38281962 DOI: 10.1186/s13073-023-01272-6  0.182
2016 Bernstein BE, Gray N, Boyd MR, Corcoran RB, Stone RM, Armand P, Sykes DB, Gopal R, Gala MK, Liu D, Tothova Z, Nodelman O, Maus MV, Wu CJ. Chabner Colloquium: Answering the Big Questions in Cancer Research & 2016 STO Annual Meeting Oncologist. 21. DOI: 10.1634/Theoncologist.2016-Ma-1  0.18
2022 Mercier FE, Shi J, Sykes DB, Oki T, Jankovic M, Man CH, Kfoury YS, Miller E, He S, Zhu A, Vasic R, Doench J, Orthwein A, Michor F, Scadden DT. In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies. Blood Advances. PMID 35793392 DOI: 10.1182/bloodadvances.2022007250  0.179
1966 Sykes D. Subcutaneous Ossification of Legs. Bmj. 2: 300-300. DOI: 10.1136/Bmj.2.5508.300-C  0.178
2015 Sykes DB, Nichols DN. There Is No Denying It, Our Medical Language Needs an Update. Journal of Graduate Medical Education. 7: 137-8. PMID 26217448 DOI: 10.4300/Jgme-D-14-00332.1  0.176
2023 Petenkova A, Auger SA, Lamb J, Quellier D, Carter C, To OT, Milosevic J, Barghout R, Kugadas A, Lu X, Geddes-McAlister J, Fichorova R, Sykes DB, Distefano MD, Gadjeva M. Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature Communications. 14: 2761. PMID 37179332 DOI: 10.1038/s41467-023-38447-z  0.176
1966 Sykes D. Venous Leg Ulcers. Bmj. 2: 1534-1534. DOI: 10.1136/Bmj.2.5528.1534  0.174
2020 Reynolds KL, Klempner SJ, Parikh A, Hochberg EP, Michaelson MD, Mooradian MJ, Lee RJ, Soumerai TE, Hobbs G, Piotrowska Z, Sykes DB, Farago AF, Bardia A, Rosovsky RP, Ryan DP. The Art of Oncology: COVID Era. The Oncologist. PMID 32697887 DOI: 10.1634/Theoncologist.2020-0512  0.173
2023 Hirz T, Mei S, Sarkar H, Kfoury Y, Wu S, Verhoeven BM, Subtelny AO, Zlatev DV, Wszolek MW, Salari K, Murray E, Chen F, Macosko EZ, Wu CL, Scadden DT, ... ... Sykes DB, et al. Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature Communications. 14: 663. PMID 36750562 DOI: 10.1038/s41467-023-36325-2  0.157
2021 Kfoury Y, Baryawno N, Severe N, Mei S, Gustafsson K, Hirz T, Brouse T, Scadden EW, Igolkina AA, Kokkaliaris K, Choi BD, Barkas N, Randolph MA, Shin JH, Saylor PJ, ... ... Sykes DB, et al. Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment. Cancer Cell. PMID 34719426 DOI: 10.1016/j.ccell.2021.09.005  0.156
1976 Jefferiss D, Gardner N, Sykes D. An academic backwater Bmj. 2: 304-304. DOI: 10.1136/Bmj.2.6033.480  0.155
2022 Mullen NJ, Thakur R, Shukla SK, Chaika NV, Kollala SS, Wang D, He C, Fujii Y, Sharma S, Mulder SE, Sykes DB, Singh PK. ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer. Cancer Letters. 552: 215981. PMID 36341997 DOI: 10.1016/j.canlet.2022.215981  0.15
2002 Breen CM, Sykes DB, Fricker G, Miller DS. Confocal imaging of organic anion transport in intact rat choroid plexus. American Journal of Physiology. Renal Physiology. 282: F877-85. PMID 11934698 DOI: 10.1152/Ajprenal.00171.2001  0.145
2023 Nunes Rosado FG, Lekovic D, Gagan J, Malter J, Chen W, Sykes DB. Comprehensive Next-Generation Sequencing Testing in a Patient with TEMPI Syndrome. Laboratory Medicine. PMID 36864546 DOI: 10.1093/labmed/lmad003  0.145
2024 Singh V, West G, Fiocchi C, Good CE, Katz J, Jacobs MR, Dichosa AEK, Flask C, Wesolowski M, McColl C, Grubb B, Ahmed S, Bank NC, Thamma K, Bederman I, ... ... Sykes DB, et al. Clonal from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn's Disease Complications. Biorxiv : the Preprint Server For Biology. PMID 38260564 DOI: 10.1101/2024.01.09.574896  0.142
2021 Sporn ZA, Fenves AZ, Sykes DB, Al-Samkari H. Severe babesiosis with associated splenic infarcts and asplenia. Proceedings (Baylor University. Medical Center). 34: 597-599. PMID 34456483 DOI: 10.1080/08998280.2021.1930632  0.14
2022 Demarest JF, Kienle M, Boytz R, Ayres M, Kim EJ, Patten JJ, Chung D, Gandhi V, Davey R, Sykes DB, Shohdy N, Pottage JC, Kumar VS. Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19. Antiviral Research. 105403. PMID 36041646 DOI: 10.1016/j.antiviral.2022.105403  0.134
2021 Nguyen GT, Xu S, Adams W, Leong JM, Bunnell SC, Mansour MK, Sykes DB, Mecsas J. Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and stimulation. Iscience. 24: 102871. PMID 34386732 DOI: 10.1016/j.isci.2021.102871  0.127
2023 Chaudagar K, Hieromnimon HM, Khurana R, Labadie B, Hirz T, Mei S, Hasan R, Shafran J, Kelley A, Apostolov E, Al-Eryani G, Harvey K, Rameshbabu S, Loyd M, Bynoe K, ... ... Sykes DB, et al. Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36862086 DOI: 10.1158/1078-0432.CCR-22-3350  0.12
2010 Wang X, Sykes DB, Miller DS. Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. Molecular Pharmacology. 78: 376-83. PMID 20547735 DOI: 10.1124/mol.110.063685  0.112
2023 Zhang M, Ceyhan Y, Mei S, Hirz T, Sykes DB, Agoulnik IU. Regulation of EZH2 Expression by INPP4B in Normal Prostate and Primary Prostate Cancer. Cancers. 15. PMID 38001678 DOI: 10.3390/cancers15225418  0.108
2004 Breen CM, Sykes DB, Baehr C, Fricker G, Miller DS. Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy. American Journal of Physiology. Renal Physiology. 287: F562-9. PMID 15126245 DOI: 10.1152/Ajprenal.00045.2003  0.107
2021 Koh SB, Dontchos BN, Bossuyt V, Edmonds C, Cristea S, Melkonjan N, Mortensen L, Ma A, Beyerlin K, Denault E, Niehoff E, Hirz T, Sykes DB, Michor F, Specht M, et al. Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses. Npj Precision Oncology. 5: 85. PMID 34548623 DOI: 10.1038/s41698-021-00224-w  0.104
2010 Baur F, Beattie D, Beer D, Bentley D, Bradley M, Bruce I, Charlton SJ, Cuenoud B, Ernst R, Fairhurst RA, Faller B, Farr D, Keller T, Fozard JR, Fullerton J, ... ... Sykes D, et al. The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. Journal of Medicinal Chemistry. 53: 3675-84. PMID 20402514 DOI: 10.1021/Jm100068M  0.1
1994 Pritchard JB, Sykes DB, Walden R, Miller DS. ATP-dependent transport of tetraethylammonium by endosomes isolated from rat renal cortex. The American Journal of Physiology. 266: F966-76. PMID 8023976 DOI: 10.1152/AJPRENAL.1994.266.6.F966  0.098
1999 Barnes DM, Sykes DB, Miller DS. Multiple effects of mercuric chloride on hexose transport in Xenopus oocytes. Biochimica Et Biophysica Acta. 1419: 289-98. PMID 10407079  0.097
2002 Barnes DM, Sykes DB, Miller DS. Mercuric chloride acting through Mg stimulates protein synthesis in Xenopus oocytes. Journal of Toxicology and Environmental Health. Part A. 65: 617-29. PMID 11991634 DOI: 10.1080/152873902317349763  0.096
1995 Barnes DM, Sykes DB, Shechter Y, Miller DS. Multiple sites of vanadate and peroxovanadate action in Xenopus oocytes. Journal of Cellular Physiology. 162: 154-61. PMID 7814448 DOI: 10.1002/Jcp.1041620119  0.085
2021 Calagua C, Ficial M, Jansen CS, Hirz T, Del Balzo L, Wilkinson S, Lake R, Ku AT, Voznesensky O, Sykes DB, Saylor PJ, Ye H, Signoretti S, Kissick H, Sowalsky AG, et al. A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34168052 DOI: 10.1158/1078-0432.CCR-21-0121  0.085
1995 Barnes DM, Sykes DB, Smith JJ, Miller DS. Magnesium-dependent stimulation of protein synthesis by the insulin mimic, pervanadate. Journal of Cellular Physiology. 164: 304-14. PMID 7542661 DOI: 10.1002/jcp.1041640211  0.084
2010 Hawkins BT, Sykes DB, Miller DS. Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1417-25. PMID 20107068 DOI: 10.1523/JNEUROSCI.5103-09.2010  0.082
2021 Scherer AK, Hopke A, Sykes DB, Irimia D, Mansour MK. Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities? Plos Pathogens. 17: e1009691. PMID 34324592 DOI: 10.1371/journal.ppat.1009691  0.078
2012 Fiez-Vandal C, Leder L, Freuler F, Sykes D, Charlton SJ, Siehler S, Schopfer U, Duckely M. HDL-like discs for assaying membrane proteins in drug discovery. Biophysical Chemistry. 56-61. PMID 22542136 DOI: 10.1016/j.bpc.2012.03.005  0.07
2014 Arnold N, Beattie D, Bradley M, Brearley A, Brown L, Charlton SJ, Fairhurst RA, Farr D, Fozard J, Fullerton J, Gosling M, Hatto J, Janus D, Jones D, Jordan L, ... ... Sykes D, et al. The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist. Bioorganic & Medicinal Chemistry Letters. 24: 4341-7. PMID 25065493 DOI: 10.1016/j.bmcl.2014.06.014  0.066
2021 Gadi SRV, Brunker PAR, Al-Samkari H, Sykes DB, Saff RR, Lo J, Bendapudi P, Leaf DE, Leaf RK. Severe Autoimmune Hemolytic Anemia Following Receipt of SARS-CoV-2 mRNA Vaccine. Transfusion. PMID 34549821 DOI: 10.1111/trf.16672  0.065
2020 Goreshnik A, Serling-Boyd N, Theodore M, Champion S, Stemmer-Rachamimov A, Sykes DB. A case of antisynthetase syndrome with thrombotic thrombocytopenic purpura. Rheumatology (Oxford, England). PMID 33221867 DOI: 10.1093/rheumatology/keaa717  0.064
2024 Butini S, Grether U, Jung KM, Ligresti A, Allarà M, Postmus AGJ, Maramai S, Brogi S, Papa A, Carullo G, Sykes D, Veprintsev D, Federico S, Grillo A, Di Guglielmo B, et al. Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of Medicinal Chemistry. PMID 38241614 DOI: 10.1021/acs.jmedchem.3c01278  0.063
2016 Auberson YP, Briard E, Sykes D, Reilly J, Healy M. Ligand Specific Efficiency (LSE) Index for PET Tracer Optimization. Chemmedchem. PMID 27193393 DOI: 10.1002/cmdc.201600112  0.061
2006 Rowell FJ, Sykes D, Grieveson L, Theaker B, Sundar L, Cumming RH. A near real-time system for continuously monitoring airborne subtilisin-type enzymes in the industrial atmosphere. Journal of Environmental Monitoring : Jem. 9: 33-43. PMID 17213940 DOI: 10.1039/b615201p  0.061
1991 Miller DS, Sykes DB. Stimulation of protein synthesis by internalized insulin. Journal of Cellular Physiology. 147: 487-94. PMID 2066368 DOI: 10.1002/jcp.1041470315  0.061
2024 Eom S, Kim S, Jackson J, Sykes D, Rahimpour S, Gorlatova M. Augmented Reality-based Contextual Guidance through Surgical Tool Tracking in Neurosurgery. Ieee Transactions On Visualization and Computer Graphics. PMID 38635386 DOI: 10.1109/TVCG.2024.3390680  0.061
2023 Kooshesh KA, Foy BH, Sykes DB, Gustafsson K, Scadden DT. Health Consequences of Thymus Removal in Adults. The New England Journal of Medicine. 389: 406-417. PMID 37530823 DOI: 10.1056/NEJMoa2302892  0.053
2016 Ho EN, Curl P, Sykes D, Wan TS. Responses to Commentary on Paper: "Controlling the misuse of cobalt in horses". Drug Testing and Analysis. PMID 27168350 DOI: 10.1002/dta.1982  0.048
2010 Sykes DB, Attar EC, Bazari H. The authors reply New England Journal of Medicine. 363: 1875. DOI: 10.1056/Nejmc1007378  0.047
2021 Burridge HC, Bhagat RK, Stettler MEJ, Kumar P, De Mel I, Demis P, Hart A, Johnson-Llambias Y, King MF, Klymenko O, McMillan A, Morawiecki P, Pennington T, Short M, Sykes D, et al. The ventilation of buildings and other mitigating measures for COVID-19: a focus on wintertime. Proceedings. Mathematical, Physical, and Engineering Sciences. 477: 20200855. PMID 35153550 DOI: 10.1098/rspa.2020.0855  0.044
2005 Monz B, Pons ME, Hampel C, Hunskaar S, Quail D, Samsioe G, Sykes D, Wagg A, Papanicolaou S. Patient-reported impact of urinary incontinence--results from treatment seeking women in 14 European countries. Maturitas. S24-34. PMID 16297579 DOI: 10.1016/j.maturitas.2005.09.005  0.041
2022 Stettler MEJ, Nishida RT, de Oliveira PM, Mesquita LCC, Johnson TJ, Galea ER, Grandison A, Ewer J, Carruthers D, Sykes D, Kumar P, Avital E, Obeysekara AIB, Doorly D, Hardalupas Y, et al. Source terms for benchmarking models of SARS-CoV-2 transmission via aerosols and droplets. Royal Society Open Science. 9: 212022. PMID 35592762 DOI: 10.1098/rsos.212022  0.04
2023 Zachrison KS, Kamalian S, Sykes DB, Brunker PAR. Case 34-2023: A 49-Year-Old Woman with Loss of Consciousness and Thrombocytopenia. The New England Journal of Medicine. 389: 1804-1811. PMID 37937781 DOI: 10.1056/NEJMcpc2300905  0.039
2004 Papanicolaou S, Sykes D, Mossialos E. EMEA and the evaluation of health-related quality of life data in the drug regulatory process. International Journal of Technology Assessment in Health Care. 20: 311-24. PMID 15446761 DOI: 10.1017/s0266462304001138  0.039
2005 Borgström F, Johnell O, Kanis JA, Oden A, Sykes D, Jönsson B. Cost effectiveness of raloxifene in the treatment of osteoporosis in Sweden: an economic evaluation based on the MORE study. Pharmacoeconomics. 22: 1153-65. PMID 15612833 DOI: 10.2165/00019053-200422170-00005  0.036
2022 Sykes DB. Auto-phlebotomy. The American Journal of Medicine. PMID 36181790 DOI: 10.1016/j.amjmed.2022.09.004  0.035
2023 Sperber J, Owolo E, Abu-Bonsrah N, Neff C, Baeta C, Sun C, Dalton T, Sykes D, Bishop BL, Kruchko C, Barnholtz-Sloan JS, Walsh KM, Larry Lo SF, Sciubba D, Ostrom QT, et al. Association Between Urbanicity and Outcomes Among Patients with Spinal Cord Ependymomas in the United States. World Neurosurgery. PMID 37619838 DOI: 10.1016/j.wneu.2023.08.062  0.03
2010 Saridogan E, Tilden D, Sykes D, Davis N, Subramanian D. Cost-Analysis Comparison of Outpatient See-and-Treat Hysteroscopy Service with Other Hysteroscopy Service Models Journal of Minimally Invasive Gynecology. 17: 518-525. PMID 20621013 DOI: 10.1016/j.jmig.2010.03.009  0.029
2024 Ammori MB, Soogumbur A, Sykes D, Francis N, Law E, Marshall P. Replacing hip precautions after hemiarthroplasty with a pose avoidance protocol. Injury. 55: 111340. PMID 38301490 DOI: 10.1016/j.injury.2024.111340  0.027
2021 Dalton T, Sykes D, Wang TY, Donnelly D, Than KD, Karikari IO, Goodwin CR, Gupta DK, Wiggins WF, Abd-El-Barr MM. Robotic-Assisted Trajectory Into Kambin's Triangle During Percutaneous Transforaminal Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy. Operative Neurosurgery (Hagerstown, Md.). PMID 34624892 DOI: 10.1093/ons/opab325  0.024
2021 Stargatt J, Bhar S, Petrovich T, Bhowmik J, Sykes D, Burns K. The Effects of Virtual Reality-Based Education on Empathy and Understanding of the Physical Environment for Dementia Care Workers in Australia: A Controlled Study. Journal of Alzheimer's Disease : Jad. 84: 1247-1257. PMID 34633323 DOI: 10.3233/JAD-210723  0.024
2005 Monz B, Hampel C, Porkess S, Wagg A, Pons ME, Samsioe G, Eliasson T, Chartier-Kastler E, Sykes D, Papanicolaou S. A description of health care provision and access to treatment for women with urinary incontinence in Europe -- a five-country comparison. Maturitas. S3-12. PMID 16297578 DOI: 10.1016/j.maturitas.2005.09.007  0.024
2015 Sykes D, Rychtář J. A game-theoretic approach to valuating toxoplasmosis vaccination strategies. Theoretical Population Biology. 105: 33-8. PMID 26319752 DOI: 10.1016/j.tpb.2015.08.003  0.023
2005 Sykes D, Castro R, Pons ME, Hampel C, Hunskaar S, Papanicolaou S, Quail D, Samsioe G, Voss S, Wagg A, Monz BU. Characteristics of female outpatients with urinary incontinence participating in a 6-month observational study in 14 European countries. Maturitas. S13-23. PMID 16297580 DOI: 10.1016/j.maturitas.2005.09.003  0.023
2013 Chadda S, Larkin M, Jones C, Sykes D, Barber B, Zhao Z, Gao S, Bengttson NO. The impact of infusion reactions associated with monoclonal antibodies in metastatic colorectal cancer: a European perspective. Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners. 19: 38-47. PMID 22735081 DOI: 10.1177/1078155212451197  0.022
2022 Tabarestani TQ, Sykes D, Murphy KR, Wang TY, Shaffrey CI, Goodwin CR, Horne P, Than KD, Abd-El-Barr MM. Beyond Placement of Pedicle Screws - New Applications for Robotics in Spine Surgery: A Multi-Surgeon, Single-Institution Experience. Frontiers in Surgery. 9: 889906. PMID 35784931 DOI: 10.3389/fsurg.2022.889906  0.021
2005 Papanicolaou S, Pons ME, Hampel C, Monz B, Quail D, Schulenburg MG, Wagg A, Sykes D. Medical resource utilisation and cost of care for women seeking treatment for urinary incontinence in an outpatient setting. Examples from three countries participating in the PURE study. Maturitas. S35-47. PMID 16297577 DOI: 10.1016/j.maturitas.2005.09.004  0.021
2015 Ho EN, Chan GH, Wan TS, Curl P, Riggs CM, Hurley MJ, Sykes D. Controlling the misuse of cobalt in horses. Drug Testing and Analysis. 7: 21-30. PMID 25256240 DOI: 10.1002/dta.1719  0.014
2005 Papanicolaou S, Hunskaar S, Lose G, Sykes D. Assessment of bothersomeness and impact on quality of life of urinary incontinence in women in France, Germany, Spain and the UK. Bju International. 96: 831-8. PMID 16153212 DOI: 10.1111/j.1464-410X.2005.05722.x  0.01
2005 Puffer S, Torgerson DJ, Sykes D, Brown P, Cooper C. Health care costs of women with symptomatic vertebral fractures. Bone. 35: 383-6. PMID 15268887 DOI: 10.1016/j.bone.2004.03.035  0.01
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