Robert Roeder - Publications

1971-1982 Washington University School of Medicine, St. Louis, MO, United States 
 1982- Rockefeller University, New York, NY, United States 
Molecular Biology

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pham P, Malik S, Mak C, Calabrese PC, Roeder RG, Goodman MF. AID-RNA polymerase II transcription-dependent deamination of IgV DNA. Nucleic Acids Research. PMID 31566237 DOI: 10.1093/nar/gkz821  0.32
2019 Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, ... ... Roeder RG, et al. The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing. Molecular Cell. PMID 31399344 DOI: 10.1016/j.molcel.2019.06.034  0.36
2019 Lu X, Chu CS, Fang T, Rayon-Estrada V, Fang F, Patke A, Qian Y, Clarke SH, Melnick AM, Zhang Y, Papavasiliou FN, Roeder RG. MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition. Cell Reports. 28: 472-485.e5. PMID 31291582 DOI: 10.1016/j.celrep.2019.06.029  0.36
2019 Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, et al. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature Communications. 10: 2314. PMID 31127101 DOI: 10.1038/s41467-019-10324-8  0.36
2019 Shimada M, Chen WY, Nakadai T, Onikubo T, Guermah M, Rhodes D, Roeder RG. Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway. Molecular Cell. PMID 30902546 DOI: 10.1016/j.molcel.2019.02.016  0.52
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, ... ... Roeder RG, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/s41586-019-1024-7  0.36
2018 Liu N, Song J, Xie Y, Wang XL, Rong B, Man N, Zhang MM, Zhang Q, Gao FF, Du MR, Zhang Y, Shen J, Xu CH, Hu CL, Wu JC, ... ... Roeder RG, et al. Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30593567 DOI: 10.1073/pnas.1809327116  0.36
2018 Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, ... ... Roeder RG, et al. Coactivator condensation at super-enhancers links phase separation and gene control. Science (New York, N.Y.). PMID 29930091 DOI: 10.1126/science.aar3958  0.32
2018 Zhang Y, Dallner OS, Nakadai T, Fayzikhodjaeva G, Lu YH, Lazar MA, Roeder RG, Friedman JM. A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891714 DOI: 10.1073/pnas.1806366115  0.36
2018 Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, ... ... Roeder RG, et al. Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets. Oncogene. PMID 29748621 DOI: 10.1038/s41388-018-0284-2  0.32
2017 Wang SP, Tang Z, Chen CW, Shimada M, Koche RP, Wang LH, Nakadai T, Chramiec A, Krivtsov AV, Armstrong SA, Roeder RG. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription. Molecular Cell. 67: 308-321.e6. PMID 28732206 DOI: 10.1016/j.molcel.2017.06.028  0.36
2016 Malik S, Roeder RG. Mediator: A Drawbridge across the Enhancer-Promoter Divide. Molecular Cell. 64: 433-434. PMID 27814486 DOI: 10.1016/j.molcel.2016.10.024  0.32
2015 Yu M, Yang W, Ni T, Tang Z, Nakadai T, Zhu J, Roeder RG. RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II. Science (New York, N.Y.). 350: 1383-6. PMID 26659056 DOI: 10.1126/science.aad2338  1
2015 Chen M, Zhu N, Liu X, Laurent B, Tang Z, Eng R, Shi Y, Armstrong SA, Roeder RG. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. Genes & Development. 29: 2123-39. PMID 26494788 DOI: 10.1101/gad.267278.115  1
2015 Hunckler MD, Tilley JM, Roeder RK. Molecular transport in collagenous tissues measured by gel electrophoresis. Journal of Biomechanics. PMID 26482732 DOI: 10.1016/j.jbiomech.2015.10.006  1
2015 Cole LE, Vargo-Gogola T, Roeder RK. Targeted delivery to bone and mineral deposits using bisphosphonate ligands. Advanced Drug Delivery Reviews. PMID 26482186 DOI: 10.1016/j.addr.2015.10.005  1
2015 Minsky N, Roeder RG. Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α. Proceedings of the National Academy of Sciences of the United States of America. 112: E5669-78. PMID 26438876 DOI: 10.1073/pnas.1516219112  1
2015 Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, Li H, Tian Q, Roeder RG, Wang G. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. The Embo Journal. PMID 26330467 DOI: 10.15252/embj.201591279  1
2015 Cole LE, Vargo-Gogola T, Roeder RK. Contrast-Enhanced X-ray Detection of Microcalcifications in Radiographically Dense Mammary Tissue Using Targeted Gold Nanoparticles. Acs Nano. 9: 8923-32. PMID 26308767 DOI: 10.1021/acsnano.5b02749  1
2015 Holt MT, David Y, Pollock S, Tang Z, Jeon J, Kim J, Roeder RG, Muir TW. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26240340 DOI: 10.1073/pnas.1504483112  1
2015 Baumann AP, Shi X, Roeder RK, Niebur GL. The sensitivity of nonlinear computational models of trabecular bone to tissue level constitutive model. Computer Methods in Biomechanics and Biomedical Engineering. 1-9. PMID 25959510 DOI: 10.1080/10255842.2015.1041022  1
2015 Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD. Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation. Molecular Cell. 58: 203-15. PMID 25818647 DOI: 10.1016/j.molcel.2015.02.029  1
2015 Nallathamby PD, Mortensen NP, Palko HA, Malfatti M, Smith C, Sonnett J, Doktycz MJ, Gu B, Roeder RK, Wang W, Retterer ST. New surface radiolabeling schemes of super paramagnetic iron oxide nanoparticles (SPIONs) for biodistribution studies. Nanoscale. 7: 6545-55. PMID 25790032 DOI: 10.1039/c4nr06441k  1
2015 Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, ... ... Roeder RG, et al. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. Cancer Cell. 27: 409-25. PMID 25759025 DOI: 10.1016/j.ccell.2015.02.003  1
2015 Baumann AP, Aref MW, Turnbull TL, Robling AG, Niebur GL, Allen MR, Roeder RK. Development of an in vivo rabbit ulnar loading model. Bone. 75: 55-61. PMID 25683214 DOI: 10.1016/j.bone.2015.01.022  1
2015 Iida S, Chen W, Nakadai T, Ohkuma Y, Roeder RG. PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1. Genes & Development. 29: 308-21. PMID 25644605 DOI: 10.1101/gad.252809.114  0.36
2015 Kane RJ, Weiss-Bilka HE, Meagher MJ, Liu Y, Gargac JA, Niebur GL, Wagner DR, Roeder RK. Hydroxyapatite reinforced collagen scaffolds with improved architecture and mechanical properties. Acta Biomaterialia. 17: 16-25. PMID 25644451 DOI: 10.1016/j.actbio.2015.01.031  1
2015 Cole LE, Ross RD, Tilley JM, Vargo-Gogola T, Roeder RK. Gold nanoparticles as contrast agents in x-ray imaging and computed tomography. Nanomedicine (London, England). 10: 321-41. PMID 25600973 DOI: 10.2217/nnm.14.171  1
2014 Roy AL, Roeder RG. Chromatin and transcriptional tango on the immune dance floor. Frontiers in Immunology. 5: 631. PMID 25566246 DOI: 10.3389/fimmu.2014.00631  1
2014 Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, ... ... Roeder RG, et al. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 26: 896-908. PMID 25464900 DOI: 10.1016/j.ccell.2014.10.009  1
2014 Cevher MA, Shi Y, Li D, Chait BT, Malik S, Roeder RG. Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit. Nature Structural & Molecular Biology. 21: 1028-34. PMID 25383669 DOI: 10.1038/nsmb.2914  1
2014 Turnbull TL, Baumann AP, Roeder RK. Fatigue microcracks that initiate fracture are located near elevated intracortical porosity but not elevated mineralization. Journal of Biomechanics. 47: 3135-42. PMID 25065731 DOI: 10.1016/j.jbiomech.2014.06.022  1
2014 Zhang P, Tu B, Wang H, Cao Z, Tang M, Zhang C, Gu B, Li Z, Wang L, Yang Y, Zhao Y, Wang H, Luo J, Deng CX, Gao B, ... Roeder RG, et al. Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion. Proceedings of the National Academy of Sciences of the United States of America. 111: 10684-9. PMID 25009184 DOI: 10.1073/pnas.1411026111  1
2014 Cole LE, Vargo-Gogola T, Roeder RK. Contrast-enhanced X-ray detection of breast microcalcifications in a murine model using targeted gold nanoparticles. Acs Nano. 8: 7486-96. PMID 24992365 DOI: 10.1021/nn5027802  1
2014 Cole LE, Vargo-Gogola T, Roeder RK. Bisphosphonate-functionalized gold nanoparticles for contrast-enhanced X-ray detection of breast microcalcifications. Biomaterials. 35: 2312-21. PMID 24360718 DOI: 10.1016/j.biomaterials.2013.11.077  1
2014 Gargac JA, Turnbull TL, Roeder RK, Niebur GL. A probabilistic damage model based on direct 3-D correlation of strain to damage formation following fatigue loading of rat femora. Journal of the Mechanical Behavior of Biomedical Materials. 30: 234-43. PMID 24333915 DOI: 10.1016/j.jmbbm.2013.11.009  1
2014 Mizuta S, Minami T, Fujita H, Kaminaga C, Matsui K, Ishino R, Fujita A, Oda K, Kawai A, Hasegawa N, Urahama N, Roeder RG, Ito M. CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 28-51. PMID 24245781 DOI: 10.1111/gtc.12104  1
2014 Ross RD, Cole LE, Tilley JMR, Roeder RK. Effects of functionalized gold nanoparticle size on X-ray attenuation and substrate binding affinity Chemistry of Materials. 26: 1187-1194. DOI: 10.1021/cm4035616  1
2013 Kim K, Lee B, Kim J, Choi J, Kim JM, Xiong Y, Roeder RG, An W. Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation. Cell Reports. 5: 1690-703. PMID 24360965 DOI: 10.1016/j.celrep.2013.11.038  1
2013 Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, ... ... Roeder RG, et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes & Development. 27: 2648-62. PMID 24285714 DOI: 10.1101/gad.232710.113  1
2013 Malik S, Roeder RG. Biochemistry. Have your PIC! Science (New York, N.Y.). 342: 706-7. PMID 24202169 DOI: 10.1126/science.1246170  1
2013 Kim DH, Tang Z, Shimada M, Fierz B, Houck-Loomis B, Bar-Dagen M, Lee S, Lee SK, Muir TW, Roeder RG, Lee JW. Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes. Molecular and Cellular Biology. 33: 4936-46. PMID 24126056 DOI: 10.1128/MCB.00601-13  1
2013 Matsui K, Oda K, Mizuta S, Ishino R, Urahama N, Hasegawa N, Roeder RG, Ito M. Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter. Biochemical and Biophysical Research Communications. 440: 184-9. PMID 24055033 DOI: 10.1016/j.bbrc.2013.09.061  1
2013 Ishino R, Minami K, Tanaka S, Nagai M, Matsui K, Hasegawa N, Roeder RG, Asano S, Ito M. FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro. Biochemical and Biophysical Research Communications. 440: 125-31. PMID 24051090 DOI: 10.1016/j.bbrc.2013.09.044  1
2013 Jiang H, Lu X, Shimada M, Dou Y, Tang Z, Roeder RG. Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95. Nature Structural & Molecular Biology. 20: 1156-63. PMID 23995757 DOI: 10.1038/nsmb.2656  1
2013 Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. H3R42me2a is a histone modification with positive transcriptional effects. Proceedings of the National Academy of Sciences of the United States of America. 110: 14894-9. PMID 23980157 DOI: 10.1073/pnas.1312925110  1
2013 Chen WY, Zhang J, Geng H, Du Z, Nakadai T, Roeder RG. A TAF4 coactivator function for E proteins that involves enhanced TFIID binding. Genes & Development. 27: 1596-609. PMID 23873942 DOI: 10.1101/gad.216192.113  1
2013 Tang Z, Chen WY, Shimada M, Nguyen UT, Kim J, Sun XJ, Sengoku T, McGinty RK, Fernandez JP, Muir TW, Roeder RG. SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53. Cell. 154: 297-310. PMID 23870121 DOI: 10.1016/j.cell.2013.06.027  1
2013 Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature. 500: 93-7. PMID 23812588 DOI: 10.1038/nature12287  1
2013 Deng C, Li Y, Liang S, Cui K, Salz T, Yang H, Tang Z, Gallagher PG, Qiu Y, Roeder R, Zhao K, Bungert J, Huang S. USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription. Plos Genetics. 9: e1003524. PMID 23754954 DOI: 10.1371/journal.pgen.1003524  1
2013 Kim J, Kim JA, McGinty RK, Nguyen UT, Muir TW, Allis CD, Roeder RG. The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation. Molecular Cell. 49: 1121-33. PMID 23453808 DOI: 10.1016/j.molcel.2013.01.034  1
2013 Lauberth SM, Nakayama T, Wu X, Ferris AL, Tang Z, Hughes SH, Roeder RG. H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation. Cell. 152: 1021-36. PMID 23452851 DOI: 10.1016/j.cell.2013.01.052  1
2013 Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG, Vakoc CR. Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 3901-6. PMID 23412334 DOI: 10.1073/pnas.1301045110  1
2013 Wilkinson AC, Ballabio E, Geng H, North P, Tapia M, Kerry J, Biswas D, Roeder RG, Allis CD, Melnick A, de Bruijn MF, Milne TA. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Reports. 3: 116-27. PMID 23352661 DOI: 10.1016/j.celrep.2012.12.016  1
2013 Conrad TL, Jaekel DJ, Kurtz SM, Roeder RK. Effects of the mold temperature on the mechanical properties and crystallinity of hydroxyapatite whisker-reinforced polyetheretherketone scaffolds. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 101: 576-83. PMID 23296754 DOI: 10.1002/jbm.b.32859  1
2013 Roeder RK. Mechanical Characterization of Biomaterials Characterization of Biomaterials. 49-104. DOI: 10.1016/B978-0-12-415800-9.00003-6  1
2013 Meagher MJ, Leone B, Turnbull TL, Ross RD, Zhang Z, Roeder RK. Dextran-encapsulated barium sulfate nanoparticles prepared for aqueous dispersion as an X-ray contrast agent Journal of Nanoparticle Research. 15. DOI: 10.1007/s11051-013-2146-8  1
2013 Roeder RK. High performance polymers Society of Plastics Engineers - Spe Medical Plastics Minitec 2013: Technology Advances in Plastic Materials and Processing For Medical Devices. 1-14.  1
2012 McCullough SD, Xu X, Dent SY, Bekiranov S, Roeder RG, Grant PA. Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 109: 21319-24. PMID 23236151 DOI: 10.1073/pnas.1218331110  1
2012 Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C, Kweon SM, Zickl L, Shojaee S, Neuberg D, Huang C, Biswas D, Xin Y, Racevskis J, Ketterling RP, ... ... Roeder RG, et al. Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discovery. 2: 1004-23. PMID 23107779 DOI: 10.1158/2159-8290.CD-12-0208  1
2012 Baumann AP, Deuerling JM, Rudy DJ, Niebur GL, Roeder RK. The relative influence of apatite crystal orientations and intracortical porosity on the elastic anisotropy of human cortical bone. Journal of Biomechanics. 45: 2743-9. PMID 23058867 DOI: 10.1016/j.jbiomech.2012.09.011  1
2012 Akalin A, Garrett-Bakelman FE, Kormaksson M, Busuttil J, Zhang L, Khrebtukova I, Milne TA, Huang Y, Biswas D, Hess JL, Allis CD, Roeder RG, Valk PJ, Löwenberg B, Delwel R, et al. Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia. Plos Genetics. 8: e1002781. PMID 22737091 DOI: 10.1371/journal.pgen.1002781  1
2012 Zaborowska J, Taylor A, Roeder RG, Murphy S. A novel TBP-TAF complex on RNA polymerase II-transcribed snRNA genes. Transcription. 3: 92-104. PMID 22441827 DOI: 10.4161/trns.19783  1
2012 Marazzi I, Ho JS, Kim J, Manicassamy B, Dewell S, Albrecht RA, Seibert CW, Schaefer U, Jeffrey KL, Prinjha RK, Lee K, García-Sastre A, Roeder RG, Tarakhovsky A. Suppression of the antiviral response by an influenza histone mimic. Nature. 483: 428-33. PMID 22419161 DOI: 10.1038/nature10892  1
2012 Kane RJ, Roeder RK. Effects of hydroxyapatite reinforcement on the architecture and mechanical properties of freeze-dried collagen scaffolds. Journal of the Mechanical Behavior of Biomedical Materials. 7: 41-9. PMID 22340683 DOI: 10.1016/j.jmbbm.2011.09.010  1
2012 Hasegawa N, Sumitomo A, Fujita A, Aritome N, Mizuta S, Matsui K, Ishino R, Inoue K, Urahama N, Nose J, Mukohara T, Kamoshida S, Roeder RG, Ito M. Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells. Molecular and Cellular Biology. 32: 1483-95. PMID 22331469 DOI: 10.1128/MCB.05245-11  1
2012 Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular Cell. 45: 330-43. PMID 22325351 DOI: 10.1016/j.molcel.2011.11.032  1
2012 Jishage M, Malik S, Wagner U, Uberheide B, Ishihama Y, Hu X, Chait BT, Gnatt A, Ren B, Roeder RG. Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Molecular Cell. 45: 51-63. PMID 22244332 DOI: 10.1016/j.molcel.2011.12.014  1
2012 Kim H, Kim K, Choi J, Heo K, Baek HJ, Roeder RG, An W. p53 requires an intact C-terminal domain for DNA binding and transactivation. Journal of Molecular Biology. 415: 843-54. PMID 22178617 DOI: 10.1016/j.jmb.2011.12.001  1
2012 Jääskeläinen T, Makkonen H, Visakorpi T, Kim J, Roeder RG, Palvimo JJ. Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth. Molecular and Cellular Endocrinology. 350: 87-98. PMID 22155569 DOI: 10.1016/j.mce.2011.11.025  1
2012 Deuerling JM, Scott Vitter J, Converse GL, Roeder RK. Micromechanical model for the orthotropic elastic constants of polyetheretherketone composites considering the orientation distribution of the hydroxyapatite whisker reinforcements Journal of Engineering Materials and Technology, Transactions of the Asme. 134. DOI: 10.1115/1.4005421  1
2012 Roeder RK, Conrad TL. Bioactive Polyaryletherketone Composites Peek Biomaterials Handbook. 163-179. DOI: 10.1016/B978-1-4377-4463-7.10011-9  1
2012 Ross RD, Cole LE, Roeder RK. Relative binding affinity of carboxylate-, phosphonate-, and bisphosphonate-functionalized gold nanoparticles targeted to damaged bone tissue Journal of Nanoparticle Research. 14. DOI: 10.1007/s11051-012-1175-z  1
2011 Xu M, Sharma P, Pan S, Malik S, Roeder RG, Martinez E. Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription. Genes & Development. 25: 2513-24. PMID 22156211 DOI: 10.1101/gad.177360.111  1
2011 Fujiki R, Hashiba W, Sekine H, Yokoyama A, Chikanishi T, Ito S, Imai Y, Kim J, He HH, Igarashi K, Kanno J, Ohtake F, Kitagawa H, Roeder RG, Brown M, et al. GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature. 480: 557-60. PMID 22121020 DOI: 10.1038/nature10656  1
2011 Shepherd TN, Zhang J, Ovaert TC, Roeder RK, Niebur GL. Direct comparison of nanoindentation and macroscopic measurements of bone viscoelasticity. Journal of the Mechanical Behavior of Biomedical Materials. 4: 2055-62. PMID 22098905 DOI: 10.1016/j.jmbbm.2011.07.004  1
2011 Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Proceedings of the National Academy of Sciences of the United States of America. 108: 15751-6. PMID 21896721 DOI: 10.1073/pnas.1111498108  1
2011 Roy AL, Sen R, Roeder RG. Enhancer-promoter communication and transcriptional regulation of Igh. Trends in Immunology. 32: 532-9. PMID 21855411 DOI: 10.1016/  1
2011 Chen W, Roeder RG. Mediator-dependent nuclear receptor function. Seminars in Cell & Developmental Biology. 22: 749-58. PMID 21854863 DOI: 10.1016/j.semcdb.2011.07.026  1
2011 Ross RD, Roeder RK. Binding affinity of surface functionalized gold nanoparticles to hydroxyapatite. Journal of Biomedical Materials Research. Part A. 99: 58-66. PMID 21793197 DOI: 10.1002/jbm.a.33165  1
2011 Wang L, Gural A, Sun XJ, Zhao X, Perna F, Huang G, Hatlen MA, Vu L, Liu F, Xu H, Asai T, Xu H, Deblasio T, Menendez S, Voza F, ... ... Roeder RG, et al. The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (New York, N.Y.). 333: 765-9. PMID 21764752 DOI: 10.1126/science.1201662  1
2011 Turnbull TL, Gargac JA, Niebur GL, Roeder RK. Detection of fatigue microdamage in whole rat femora using contrast-enhanced micro-computed tomography. Journal of Biomechanics. 44: 2395-400. PMID 21764062 DOI: 10.1016/j.jbiomech.2011.06.032  1
2011 Shema E, Kim J, Roeder RG, Oren M. RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. Molecular Cell. 42: 477-88. PMID 21596312 DOI: 10.1016/j.molcel.2011.03.011  1
2011 Ren X, Siegel R, Kim U, Roeder RG. Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication. Molecular Cell. 42: 342-55. PMID 21549311 DOI: 10.1016/j.molcel.2011.04.011  1
2011 Rudy DJ, Deuerling JM, Espinoza Orías AA, Roeder RK. Anatomic variation in the elastic inhomogeneity and anisotropy of human femoral cortical bone tissue is consistent across multiple donors. Journal of Biomechanics. 44: 1817-20. PMID 21543070 DOI: 10.1016/j.jbiomech.2011.04.009  1
2011 Kim J, Roeder RG. Nucleosomal H2B ubiquitylation with purified factors. Methods (San Diego, Calif.). 54: 331-8. PMID 21443952 DOI: 10.1016/j.ymeth.2011.03.009  1
2011 Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG. Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell. 144: 513-25. PMID 21335234 DOI: 10.1016/j.cell.2011.01.020  1
2011 Alam I, Koller DL, Sun Q, Roeder RK, Cañete T, Blázquez G, López-Aumatell R, Martínez-Membrives E, Vicens-Costa E, Mont C, Díaz S, Tobeña A, Fernández-Teruel A, Whitley A, Strid P, et al. Heterogeneous stock rat: a unique animal model for mapping genes influencing bone fragility. Bone. 48: 1169-77. PMID 21334473 DOI: 10.1016/j.bone.2011.02.009  1
2011 Park JH, Smith RJ, Shieh SY, Roeder RG. The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability. The Journal of Biological Chemistry. 286: 10911-7. PMID 21317290 DOI: 10.1074/jbc.C110.210211  1
2011 Liu X, Wang D, Zhao Y, Tu B, Zheng Z, Wang L, Wang H, Gu W, Roeder RG, Zhu WG. Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). Proceedings of the National Academy of Sciences of the United States of America. 108: 1925-30. PMID 21245319 DOI: 10.1073/pnas.1019619108  1
2011 Landrigan MD, Li J, Turnbull TL, Burr DB, Niebur GL, Roeder RK. Contrast-enhanced micro-computed tomography of fatigue microdamage accumulation in human cortical bone. Bone. 48: 443-50. PMID 20951850 DOI: 10.1016/j.bone.2010.10.160  1
2011 Roeder RK, Nychka JA. Biomaterials in regenerative medicine: Promises and progress Jom. 63: 50+55. DOI: 10.1007/s11837-011-0059-5  1
2010 Deuerling JM, Rudy DJ, Niebur GL, Roeder RK. Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom. Medical Physics. 37: 5138-45. PMID 20964233 DOI: 10.1118/1.3480507  1
2010 Malik S, Roeder RG. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nature Reviews. Genetics. 11: 761-72. PMID 20940737 DOI: 10.1038/nrg2901  1
2010 Dumay-Odelot H, Durrieu-Gaillard S, Da Silva D, Roeder RG, Teichmann M. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Cell Cycle (Georgetown, Tex.). 9: 3687-99. PMID 20890107 DOI: 10.4161/cc.9.18.13203  1
2010 Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M. The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression. Molecular and Cellular Biology. 30: 4818-27. PMID 20713445 DOI: 10.1128/MCB.01348-09  1
2010 Kane RJ, Yue W, Mason JJ, Roeder RK. Improved fatigue life of acrylic bone cements reinforced with zirconia fibers. Journal of the Mechanical Behavior of Biomedical Materials. 3: 504-11. PMID 20696415 DOI: 10.1016/j.jmbbm.2010.05.007  1
2010 Zhang Z, Ross RD, Roeder RK. Preparation of functionalized gold nanoparticles as a targeted X-ray contrast agent for damaged bone tissue. Nanoscale. 2: 582-6. PMID 20644762 DOI: 10.1039/b9nr00317g  1
2010 Milne TA, Kim J, Wang GG, Stadler SC, Basrur V, Whitcomb SJ, Wang Z, Ruthenburg AJ, Elenitoba-Johnson KS, Roeder RG, Allis CD. Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. Molecular Cell. 38: 853-63. PMID 20541448 DOI: 10.1016/j.molcel.2010.05.011  1
2010 Chen W, Zhang X, Birsoy K, Roeder RG. A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 10196-201. PMID 20479251 DOI: 10.1073/pnas.1005626107  1
2010 Jiang P, Hu Q, Ito M, Meyer S, Waltz S, Khan S, Roeder RG, Zhang X. Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 107: 6765-70. PMID 20351249 DOI: 10.1073/pnas.1001814107  1
2010 Park JH, Sun XJ, Roeder RG. The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expression. Molecular and Cellular Biology. 30: 2750-61. PMID 20351180 DOI: 10.1128/MCB.00804-09  1
2010 Grøntved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S. MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis. Molecular and Cellular Biology. 30: 2155-69. PMID 20194623 DOI: 10.1128/MCB.01238-09  1
2010 Kim J, Guermah M, Roeder RG. The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. Cell. 140: 491-503. PMID 20178742 DOI: 10.1016/j.cell.2009.12.050  1
2010 Haurie V, Durrieu-Gaillard S, Dumay-Odelot H, Da Silva D, Rey C, Prochazkova M, Roeder RG, Besser D, Teichmann M. Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation. Proceedings of the National Academy of Sciences of the United States of America. 107: 4176-81. PMID 20154270 DOI: 10.1073/pnas.0914980107  1
2010 Landrigan MD, Flatley JC, Turnbull TL, Kruzic JJ, Ferracane JL, Hilton TJ, Roeder RK. Detection of dentinal cracks using contrast-enhanced micro-computed tomography. Journal of the Mechanical Behavior of Biomedical Materials. 3: 223-7. PMID 20129422 DOI: 10.1016/j.jmbbm.2009.10.003  1
2010 Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. The Journal of Biological Chemistry. 285: 2601-9. PMID 19880525 DOI: 10.1074/jbc.M109.021824  1
2010 Converse GL, Conrad TL, Merrill CH, Roeder RK. Hydroxyapatite whisker-reinforced polyetherketoneketone bone ingrowth scaffolds. Acta Biomaterialia. 6: 856-63. PMID 19665061 DOI: 10.1016/j.actbio.2009.08.004  1
2010 Deuerling JM, Roeder RK. The orientation distribution of apatite crystals accounts for variability in the elastic anisotropy of human cortical bone tissue Asme 2010 Summer Bioengineering Conference, Sbc 2010. 339-340. DOI: 10.1115/SBC2010-19481  1
2010 Rudy DJ, Deuerling JM, Espinoza Orías AA, Roeder RK. Anatomic variation in the elastic inhomogeneity and anisotropy of cortical bone tissue is consistent across multiple donors Asme 2010 Summer Bioengineering Conference, Sbc 2010. 695-696. DOI: 10.1115/SBC2010-19467  1
2010 Roeder RK. A paradigm for the integration of biology in materials science and engineering Jom. 62: 49-55. DOI: 10.1007/s11837-010-0108-5  1
2010 Narayan RJ, Roeder RK. Recent advances in biological materials science and biomedical materials Jom. 62: 38. DOI: 10.1007/s11837-010-0106-7  1
2009 Lee S, Roeder RG, Lee JW. Roles of histone H3-lysine 4 methyltransferase complexes in NR-mediated gene transcription. Progress in Molecular Biology and Translational Science. 87: 343-82. PMID 20374709 DOI: 10.1016/S1877-1173(09)87010-5  1
2009 Chen W, Yang Q, Roeder RG. Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene. Molecular Cell. 35: 755-68. PMID 19782026 DOI: 10.1016/j.molcel.2009.09.015  1
2009 Converse GL, Conrad TL, Roeder RK. Mechanical properties of hydroxyapatite whisker reinforced polyetherketoneketone composite scaffolds. Journal of the Mechanical Behavior of Biomedical Materials. 2: 627-35. PMID 19716108 DOI: 10.1016/j.jmbbm.2009.07.002  1
2009 Roeder RK. 4th TMS Symposium on Biological Materials Science. Journal of the Mechanical Behavior of Biomedical Materials. 2: 579. PMID 19716100 DOI: 10.1016/j.jmbbm.2009.07.003  1
2009 Deuerling JM, Yue W, Espinoza Orías AA, Roeder RK. Specimen-specific multi-scale model for the anisotropic elastic constants of human cortical bone. Journal of Biomechanics. 42: 2061-7. PMID 19664772 DOI: 10.1016/j.jbiomech.2009.06.002  1
2009 Espinoza Orías AA, Deuerling JM, Landrigan MD, Renaud JE, Roeder RK. Anatomic variation in the elastic anisotropy of cortical bone tissue in the human femur. Journal of the Mechanical Behavior of Biomedical Materials. 2: 255-63. PMID 19627830 DOI: 10.1016/j.jmbbm.2008.08.005  1
2009 Kim J, Roeder RG. Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast. The Journal of Biological Chemistry. 284: 20582-92. PMID 19531475 DOI: 10.1074/jbc.M109.017442  1
2009 Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, Roeder RG, Lee JW. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8513-8. PMID 19433796 DOI: 10.1073/pnas.0902873106  1
2009 Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell. 137: 459-71. PMID 19410543 DOI: 10.1016/j.cell.2009.02.027  1
2009 Landrigan MD, Roeder RK. Systematic error in mechanical measures of damage during four-point bending fatigue of cortical bone. Journal of Biomechanics. 42: 1212-7. PMID 19394019 DOI: 10.1016/j.jbiomech.2009.03.016  1
2009 Fujiki R, Chikanishi T, Hashiba W, Ito H, Takada I, Roeder RG, Kitagawa H, Kato S. GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Nature. 459: 455-9. PMID 19377461 DOI: 10.1038/nature07954  1
2009 Guermah M, Kim J, Roeder RG. Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system. Methods (San Diego, Calif.). 48: 353-60. PMID 19272450 DOI: 10.1016/j.ymeth.2009.02.022  1
2009 Gamper AM, Kim J, Roeder RG. The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. Molecular and Cellular Biology. 29: 266-80. PMID 18936164 DOI: 10.1128/MCB.00315-08  1
2009 Narayan RJ, Roeder RK. The development of novel materials for medical devices Jom. 61: 13. DOI: 10.1007/s11837-009-0125-4  1
2008 Kane RJ, Converse GL, Roeder RK. Effects of the reinforcement morphology on the fatigue properties of hydroxyapatite reinforced polymers. Journal of the Mechanical Behavior of Biomedical Materials. 1: 261-8. PMID 19578474 DOI: 10.1016/j.jmbbm.2008.01.004  1
2008 Ozsolak F, Poling LL, Wang Z, Liu H, Liu XS, Roeder RG, Zhang X, Song JS, Fisher DE. Chromatin structure analyses identify miRNA promoters. Genes & Development. 22: 3172-83. PMID 19056895 DOI: 10.1101/gad.1706508  1
2008 Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, Lee SK, Chan L, Roeder RG, Lee JW. Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19229-34. PMID 19047629 DOI: 10.1073/pnas.0810100105  1
2008 El-Osta A, Brasacchio D, Yao D, Pocai A, Jones PL, Roeder RG, Cooper ME, Brownlee M. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. The Journal of Experimental Medicine. 205: 2409-17. PMID 18809715 DOI: 10.1084/jem.20081188  1
2008 Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR. CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. Molecular Cell. 31: 510-9. PMID 18722177 DOI: 10.1016/j.molcel.2008.08.001  1
2008 Malik S, Roeder RG. Epigenetics? Mediator does that too! Molecular Cell. 31: 305-6. PMID 18691961 DOI: 10.1016/j.molcel.2008.07.011  1
2008 Robinson PJ, An W, Routh A, Martino F, Chapman L, Roeder RG, Rhodes D. 30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction. Journal of Molecular Biology. 381: 816-25. PMID 18653199 DOI: 10.1016/j.jmb.2008.04.050  1
2008 Mertens C, Roeder RG. Different functional modes of p300 in activation of RNA polymerase III transcription from chromatin templates. Molecular and Cellular Biology. 28: 5764-76. PMID 18644873 DOI: 10.1128/MCB.01262-07  1
2008 McGinty RK, Kim J, Chatterjee C, Roeder RG, Muir TW. Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation. Nature. 453: 812-6. PMID 18449190 DOI: 10.1038/nature06906  1
2008 Leng H, Wang X, Ross RD, Niebur GL, Roeder RK. Micro-computed tomography of fatigue microdamage in cortical bone using a barium sulfate contrast agent. Journal of the Mechanical Behavior of Biomedical Materials. 1: 68-75. PMID 18443659 DOI: 10.1016/j.jmbbm.2007.06.002  1
2008 Woiwode A, Johnson SA, Zhong S, Zhang C, Roeder RG, Teichmann M, Johnson DL. PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex. Molecular and Cellular Biology. 28: 4204-14. PMID 18391023 DOI: 10.1128/MCB.01912-07  1
2008 Peng Y, Chen F, Melamed J, Chiriboga L, Wei J, Kong X, McLeod M, Li Y, Li CX, Feng A, Garabedian MJ, Wang Z, Roeder RG, Lee P. Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 5236-41. PMID 18356297 DOI: 10.1073/pnas.0712262105  1
2008 Gamper AM, Roeder RG. Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage. Molecular and Cellular Biology. 28: 2517-27. PMID 18250150 DOI: 10.1128/MCB.01461-07  1
2008 Ge K, Cho YW, Guo H, Hong TB, Guermah M, Ito M, Yu H, Kalkum M, Roeder RG. Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Molecular and Cellular Biology. 28: 1081-91. PMID 18039840 DOI: 10.1128/MCB.00967-07  1
2008 Roeder RK, Converse GL, Kane RJ, Yue W. Hydroxyapatite-reinforced polymer biocomposites for synthetic bone substitutes Jom. 60: 38-45. DOI: 10.1007/s11837-008-0030-2  1
2007 Chen W, Roeder RG. The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation. Nucleic Acids Research. 35: 6161-9. PMID 17827210 DOI: 10.1093/nar/gkm661  1
2007 Wang X, Masse DB, Leng H, Hess KP, Ross RD, Roeder RK, Niebur GL. Detection of trabecular bone microdamage by micro-computed tomography. Journal of Biomechanics. 40: 3397-403. PMID 17588588 DOI: 10.1016/j.jbiomech.2007.05.009  1
2007 Converse GL, Yue W, Roeder RK. Processing and tensile properties of hydroxyapatite-whisker-reinforced polyetheretherketone. Biomaterials. 28: 927-35. PMID 17113143 DOI: 10.1016/j.biomaterials.2006.10.031  1
2007 Landrigan MD, Roeder RK. Systematic error in the measure of microdamage by modulus degradation during four-point bending fatigue Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 843-844.  1
2007 Deuerling JM, Yue W, Orias AAE, Roeder RK. Specimen-specific multiscale model for the anisotropic elastic properties of human cortical bone tissue Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 845-846.  1
2007 Penninger CL, Roeder RK, Niebur GL, Renaud JE. Investigation of osteoclast resorption mechanisms in a hybrid cellular automaton model of bone remodeling Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 351-352.  1
2006 Stumpf M, Waskow C, Krötschel M, van Essen D, Rodriguez P, Zhang X, Guyot B, Roeder RG, Borggrefe T. The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proceedings of the National Academy of Sciences of the United States of America. 103: 18504-9. PMID 17132730 DOI: 10.1073/pnas.0604494103  1
2006 Wang X, Yang N, Uno E, Roeder RG, Guo S. A subunit of the mediator complex regulates vertebrate neuronal development. Proceedings of the National Academy of Sciences of the United States of America. 103: 17284-9. PMID 17088561 DOI: 10.1073/pnas.0605414103  1
2006 Lee S, Lee DK, Dou Y, Lee J, Lee B, Kwak E, Kong YY, Lee SK, Roeder RG, Lee JW. Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proceedings of the National Academy of Sciences of the United States of America. 103: 15392-7. PMID 17021013 DOI: 10.1073/pnas.0607313103  1
2006 Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nature Structural & Molecular Biology. 13: 713-9. PMID 16878130 DOI: 10.1038/nsmb1128  1
2006 Vermeulen M, Walter W, Le Guezennec X, Kim J, Edayathumangalam RS, Lasonder E, Luger K, Roeder RG, Logie C, Berger SL, Stunnenberg HG. A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and Cellular Biology. 26: 5226-36. PMID 16809761 DOI: 10.1128/MCB.00440-06  1
2006 Plevin MJ, Zhang J, Guo C, Roeder RG, Ikura M. The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain. Proceedings of the National Academy of Sciences of the United States of America. 103: 10242-7. PMID 16803958 DOI: 10.1073/pnas.0603463103  1
2006 Hu X, Malik S, Negroiu CC, Hubbard K, Velalar CN, Hampton B, Grosu D, Catalano J, Roeder RG, Gnatt A. A Mediator-responsive form of metazoan RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 103: 9506-11. PMID 16769904 DOI: 10.1073/pnas.0603702103  1
2006 Shen RR, Ferguson DO, Renard M, Hoyer KK, Kim U, Hao X, Alt FW, Roeder RG, Morse HC, Teitell MA. Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood. 108: 1991-8. PMID 16728701 DOI: 10.1182/blood-2006-02-001354  1
2006 Siegel R, Kim U, Patke A, Yu X, Ren X, Tarakhovsky A, Roeder RG. Nontranscriptional regulation of SYK by the coactivator OCA-B is required at multiple stages of B cell development. Cell. 125: 761-74. PMID 16713566 DOI: 10.1016/j.cell.2006.03.036  1
2006 Park JH, Roeder RG. GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation. Molecular and Cellular Biology. 26: 4006-16. PMID 16705155 DOI: 10.1128/MCB.02185-05  1
2006 Guermah M, Palhan VB, Tackett AJ, Chait BT, Roeder RG. Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell. 125: 275-86. PMID 16630816 DOI: 10.1016/j.cell.2006.01.055  1
2006 Baek HJ, Kang YK, Roeder RG. Human Mediator enhances basal transcription by facilitating recruitment of transcription factor IIB during preinitiation complex assembly. The Journal of Biological Chemistry. 281: 15172-81. PMID 16595664 DOI: 10.1074/jbc.M601983200  1
2006 Yu X, Siegel R, Roeder RG. Interaction of the B cell-specific transcriptional coactivator OCA-B and galectin-1 and a possible role in regulating BCR-mediated B cell proliferation. The Journal of Biological Chemistry. 281: 15505-16. PMID 16565088 DOI: 10.1074/jbc.M509041200  1
2006 Doyen CM, An W, Angelov D, Bondarenko V, Mietton F, Studitsky VM, Hamiche A, Roeder RG, Bouvet P, Dimitrov S. Mechanism of polymerase II transcription repression by the histone variant macroH2A. Molecular and Cellular Biology. 26: 1156-64. PMID 16428466 DOI: 10.1128/MCB.26.3.1156-1164.2006  1
2005 Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. MLL associates specifically with a subset of transcriptionally active target genes. Proceedings of the National Academy of Sciences of the United States of America. 102: 14765-70. PMID 16199523 DOI: 10.1073/pnas.0503630102  1
2005 Park SW, Li G, Lin YP, Barrero MJ, Ge K, Roeder RG, Wei LN. Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. Molecular Cell. 19: 643-53. PMID 16137621 DOI: 10.1016/j.molcel.2005.08.008  1
2005 Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 121: 873-85. PMID 15960975 DOI: 10.1016/j.cell.2005.04.031  1
2005 Malik S, Baek HJ, Wu W, Roeder RG. Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator. Molecular and Cellular Biology. 25: 2117-29. PMID 15743810 DOI: 10.1128/MCB.25.6.2117-2129.2005  0.32
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, ... ... Roeder RG, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/j.molcel.2004.05.011  1
2003 Gwack Y, Baek HJ, Nakamura H, Lee SH, Meisterernst M, Roeder RG, Jung JU. Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation. Molecular and Cellular Biology. 23: 2055-67. PMID 12612078  0.32
2002 Malik S, Wallberg AE, Kang YK, Roeder RG. TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Molecular and Cellular Biology. 22: 5626-37. PMID 12101254  0.32
2002 Ito M, Okano HJ, Darnell RB, Roeder RG. The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development Embo Journal. 21: 3464-3475. PMID 12093747 DOI: 10.1093/emboj/cdf348  1
2002 Baek HJ, Malik S, Qin J, Roeder RG. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Molecular and Cellular Biology. 22: 2842-52. PMID 11909976  0.32
2002 Kang YK, Guermah M, Yuan CX, Roeder RG. The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. Proceedings of the National Academy of Sciences of the United States of America. 99: 2642-7. PMID 11867769 DOI: 10.1073/pnas.261715899  0.52
1998 Oelgeschläger T, Tao Y, Kang YK, Roeder RG. Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs. Molecular Cell. 1: 925-31. PMID 9660976  0.64
1997 Hoffmann A, Oelgeschläger T, Roeder RG. Considerations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions? Proceedings of the National Academy of Sciences of the United States of America. 94: 8928-35. PMID 9256411  1
1996 Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192  1
1996 Hoffmann A, Roeder RG. Cloning and characterization of human TAF20/15. Multiple interactions suggest a central role in TFIID complex formation. The Journal of Biological Chemistry. 271: 18194-202. PMID 8663456 DOI: 10.1074/jbc.271.30.18194  1
1996 Hoffmann A, Chiang CM, Oelgeschläger T, Xie X, Burley SK, Nakatani Y, Roeder RG. A histone octamer-like structure within TFIID. Nature. 380: 356-9. PMID 8598932 DOI: 10.1038/380356a0  1
1996 Xie X, Kokubo T, Cohen SL, Mirza UA, Hoffmann A, Chait BT, Roeder RG, Nakatani Y, Burley SK. Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature. 380: 316-22. PMID 8598927 DOI: 10.1038/380316a0  1
1993 Chiang CM, Ge H, Wang Z, Hoffmann A, Roeder RG. Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. The Embo Journal. 12: 2749-62. PMID 7687540  1
1992 Takada R, Nakatani Y, Hoffmann A, Kokubo T, Hasegawa S, Roeder RG, Horikoshi M. Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau). Proceedings of the National Academy of Sciences of the United States of America. 89: 11809-13. PMID 1465404  1
1992 Nikolov DB, Hu SH, Lin J, Gasch A, Hoffmann A, Horikoshi M, Chua NH, Roeder RG, Burley SK. Crystal structure of TFIID TATA-box binding protein. Nature. 360: 40-6. PMID 1436073 DOI: 10.1038/360040a0  1
1991 Hoffmann A, Roeder RG. Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Research. 19: 6337-8. PMID 1956801 DOI: 10.1093/nar/19.22.6337  0.88
1991 Ohkuma Y, Sumimoto H, Hoffmann A, Shimasaki S, Horikoshi M, Roeder RG. Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. Nature. 354: 398-401. PMID 1956403 DOI: 10.1038/354398a0  1
1991 Tamura T, Sumita K, Fujino I, Aoyama A, Horikoshi M, Hoffmann A, Roeder RG, Muramatsu M, Mikoshiba K. Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID). Nucleic Acids Research. 19: 3861-5. PMID 1861978  1
1990 Hoffmann A, Horikoshi M, Wang CK, Schroeder S, Weil PA, Roeder RG. Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID. Genes & Development. 4: 1141-8. PMID 2210373  1
1990 Gasch A, Hoffmann A, Horikoshi M, Roeder RG, Chua NH. Arabidopsis thaliana contains two genes for TFIID. Nature. 346: 390-4. PMID 2197561 DOI: 10.1038/346390a0  1
1990 Muhich ML, Iida CT, Horikoshi M, Roeder RG, Parker CS. cDNA clone encoding Drosophila transcription factor TFIID. Proceedings of the National Academy of Sciences of the United States of America. 87: 9148-52. PMID 2123550  1
1988 O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485  1
1988 LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460  1
1987 Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0  1
1986 Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962  1
1986 Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588  1
1985 Lassar AB, Hamer DH, Roeder RG. Stable transcription complex on a class III gene in a minichromosome. Molecular and Cellular Biology. 5: 40-5. PMID 2984553  1
1984 Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823  1
1984 Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888  1
1983 Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409  1
1983 Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359  1
1983 Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835  1
1983 Lassar AB, Martin PL, Roeder RG. Transcription of class III genes: formation of preinitiation complexes. Science (New York, N.Y.). 222: 740-8. PMID 6356356  1
1981 Sakonju S, Brown DD, Engelke D, Ng SY, Shastry BS, Roeder RG. The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell. 23: 665-9. PMID 7226225 DOI: 10.1016/0092-8674(81)90429-3  1
1981 Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1  1
1980 Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7  1
1979 Ng SY, Parker CS, Roeder RG. Transcription of cloned Xenopus 5S RNA genes by X. laevis RNA polymerase III in reconstituted systems. Proceedings of the National Academy of Sciences of the United States of America. 76: 136-40. PMID 284325  1
1978 Parker CS, Jaehning JA, Roeder RG. Faithful gene transcription by eukaryotic RNA polymerases in reconstructed systems. Cold Spring Harbor Symposia On Quantitative Biology. 42: 577-87. PMID 277365  1
1977 Parker CS, Roeder RG. Selective and accurate transcription of the Xenopus laevis 5S RNA genes in isolated chromatin by purified RNA polymerase III. Proceedings of the National Academy of Sciences of the United States of America. 74: 44-8. PMID 264693  1
1970 Roeder RG, Rutter WJ. Multiple ribonucleic acid polymerases and ribonucleic acid synthesis during sea urchin development. Biochemistry. 9: 2543-53. PMID 5423271  1
1970 Roeder RG, Rutter WJ. Specific nucleolar and nucleoplasmic RNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 65: 675-82. PMID 5267147  1
1970 Lindell TJ, Weinberg F, Morris PW, Roeder RG, Rutter WJ. Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (New York, N.Y.). 170: 447-9. PMID 4918258  1
1969 Roeder RG, Rutter WJ. Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature. 224: 234-7. PMID 5344598 DOI: 10.1038/224234a0  1
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