Jonathan R. Beckwith - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
bacterial genetics
Website:
http://beck2.med.harvard.edu/people/people.htm

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hatahet F, Blazyk JL, Martineau E, Mandela E, Zhao Y, Campbell RE, Beckwith J, Boyd D. Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598701 DOI: 10.1073/pnas.1521260112  1
2015 Williamson JA, Cho SH, Ye J, Collet JF, Beckwith JR, Chou JJ. Structure and multistate function of the transmembrane electron transporter CcdA. Nature Structural & Molecular Biology. PMID 26389738 DOI: 10.1038/nsmb.3099  1
2015 Landeta C, Blazyk JL, Hatahet F, Meehan BM, Eser M, Myrick A, Bronstain L, Minami S, Arnold H, Ke N, Rubin EJ, Furie BC, Furie B, Beckwith J, Dutton R, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nature Chemical Biology. 11: 292-8. PMID 25686372 DOI: 10.1038/nchembio.1752  1
2014 Beckwith J. Mission possible: Getting to yes with François Jacob Research in Microbiology. 165: 348-350. PMID 24859134 DOI: 10.1016/j.resmic.2014.05.015  1
2014 Hatahet F, Boyd D, Beckwith J. Disulfide bond formation in prokaryotes: History, diversity and design Biochimica Et Biophysica Acta - Proteins and Proteomics. 1844: 1402-1414. PMID 24576574 DOI: 10.1016/j.bbapap.2014.02.014  1
2014 Dwyer RS, Malinverni JC, Boyd D, Beckwith J, Silhavy TJ. Folding LacZ in the periplasm of Escherichia coli Journal of Bacteriology. 196: 3343-3350. DOI: 10.1128/JB.01843-14  1
2013 Beckwith J. Fifty years fused to lac Annual Review of Microbiology. 67: 1-19. PMID 24024632 DOI: 10.1146/annurev-micro-092412-155732  1
2013 Beckwith J, Yaniv M. François Jacob (1920-2013) Current Biology : Cb. 23: R422-425. PMID 23841128  1
2013 Beckwith J. The Sec-dependent pathway Research in Microbiology. 164: 497-504. PMID 23538404 DOI: 10.1016/j.resmic.2013.03.007  1
2012 Chng SS, Xue M, Garner RA, Kadokura H, Boyd D, Beckwith J, Kahne D. Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (New York, N.Y.). 337: 1665-8. PMID 22936569 DOI: 10.1126/science.1227215  1
2012 Chng SS, Dutton RJ, Denoncin K, Vertommen D, Collet JF, Kadokura H, Beckwith J. Overexpression of the rhodanese PspE, a single cysteine-containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA. Molecular Microbiology. 85: 996-1006. PMID 22809289 DOI: 10.1111/j.1365-2958.2012.08157.x  1
2012 Cho SH, Parsonage D, Thurston C, Dutton RJ, Poole LB, Collet JF, Beckwith J. A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope. Mbio. 3. PMID 22493033 DOI: 10.1128/mBio.00291-11  1
2012 Feeney MA, Ke N, Beckwith J. Mutations at several loci cause increased expression of ribonucleotide reductase in Escherichia coli. Journal of Bacteriology. 194: 1515-22. PMID 22247510 DOI: 10.1128/JB.05989-11  1
2012 Beckwith J, Morris-Singer CA. Missing heritability: Hidden environment in genetic studies of human behavior Evolution and Morality: Nomos Lii. 100-112.  1
2011 Robichon C, Karimova G, Beckwith J, Ladant D. Role of leucine zipper motifs in association of the Escherichia coli cell division proteins FtsL and FtsB Journal of Bacteriology. 193: 4988-4992. PMID 21784946 DOI: 10.1128/JB.00324-11  1
2011 Feeney MA, Veeravalli K, Boyd D, Gon S, Faulkner MJ, Georgiou G, Beckwith J. Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 108: 7991-6. PMID 21521794 DOI: 10.1073/pnas.1105429108  1
2011 Beckwith J. The operon as paradigm: Normal science and the beginning of biological complexity Journal of Molecular Biology. 409: 7-13. PMID 21334345 DOI: 10.1016/j.jmb.2011.02.027  1
2011 Veeravalli K, Boyd D, Iverson BL, Beckwith J, Georgiou G. Laboratory evolution of glutathione biosynthesis reveals natural compensatory pathways. Nature Chemical Biology. 7: 101-5. PMID 21186348 DOI: 10.1038/nchembio.499  1
2011 Wang X, Dutton RJ, Beckwith J, Boyd D. Membrane topology and mutational analysis of mycobacterium tuberculosis VKOR, a protein involved in disulfide bond formation and a homologue of human vitamin K epoxide reductase Antioxidants and Redox Signaling. 14: 1413-1420. PMID 20969481 DOI: 10.1089/ars.2010.3558  1
2010 Huber D, Chaffotte A, Eser M, Planson AG, Beckwith J. Amino acid residues important for folding of thioredoxin are revealed only by study of the physiologically relevant reduced form of the protein. Biochemistry. 49: 8922-8. PMID 20873718 DOI: 10.1021/bi100784h  1
2010 Rowland SL, Wadsworth KD, Robson SA, Robichon C, Beckwith J, King GF. Evidence from artificial septal targeting and site-directed mutagenesis that residues in the extracytoplasmic β domain of DivIB mediate its interaction with the divisomal transpeptidase PBP 2B Journal of Bacteriology. 192: 6116-6125. PMID 20870765 DOI: 10.1128/JB.00783-10  1
2010 Vashlishan Murray AB, Carson MJ, Morris CA, Beckwith J. Illusions of scientific legitimacy: misrepresented science in the direct-to-consumer genetic-testing marketplace. Trends in Genetics : Tig. 26: 459-61. PMID 20828856 DOI: 10.1016/j.tig.2010.08.001  1
2010 Elgán TH, Planson AG, Beckwith J, Güntert P, Berndt KD. Determinants of activity in glutaredoxins: An in vitro evolved Grx1-like variant of Escherichia coli Grx3 Biochemical Journal. 430: 487-495. PMID 20604742 DOI: 10.1042/BJ20100289  1
2010 Kadokura H, Beckwith J. Mechanisms of oxidative protein folding in the bacterial cell envelope Antioxidants and Redox Signaling. 13: 1231-1246. PMID 20367276 DOI: 10.1089/ars.2010.3187  1
2010 Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA. Structure of a bacterial homologue of vitamin K epoxide reductase. Nature. 463: 507-12. PMID 20110994 DOI: 10.1038/nature08720  1
2010 Dutton RJ, Wayman A, Wei JR, Rubin EJ, Beckwith J, Boyd D. Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin. Proceedings of the National Academy of Sciences of the United States of America. 107: 297-301. PMID 20018758 DOI: 10.1073/pnas.0912952107  1
2010 Shouldice SR, Cho SH, Boyd D, Heras B, Eser M, Beckwith J, Riggs P, Martin JL, Berkmen M. In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling Molecular Microbiology. 75: 13-28. PMID 19968787 DOI: 10.1111/j.1365-2958.2009.06952.x  1
2010 Gonzalez MD, Akbay EA, Boyd D, Beckwith J. Multiple interaction domains in FtsL, a protein component of the widely conserved bacterial FtsLBQ cell division complex Journal of Bacteriology. 192: 2757-2768. DOI: 10.1128/JB.01609-09  1
2009 Kadokura H, Beckwith J. Detecting Folding Intermediates of a Protein as It Passes through the Bacterial Translocation Channel Cell. 138: 1164-1173. PMID 19766568 DOI: 10.1016/j.cell.2009.07.030  1
2009 Perez-Jimenez R, Li J, Kosuri P, Sanchez-Romero I, Wiita AP, Rodriguez-Larrea D, Chueca A, Holmgren A, Miranda-Vizuete A, Becker K, Cho SH, Beckwith J, Gelhaye E, Jacquot JP, Gaucher EA, et al. Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology. 16: 890-6. PMID 19597482 DOI: 10.1038/nsmb.1627  1
2009 Cho SH, Beckwith J. Two snapshots of electron transport across the membrane: Insights into the structure and function of DsbD Journal of Biological Chemistry. 284: 11416-11424. PMID 19258316 DOI: 10.1074/jbc.M900651200  1
2009 Eser M, Masip L, Kadokura H, Georgiou G, Beckwith J. Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm. Proceedings of the National Academy of Sciences of the United States of America. 106: 1572-7. PMID 19164554 DOI: 10.1073/pnas.0812596106  1
2009 Beckwith J. Genetic suppressors and recovery of repressed biochemical memory Journal of Biological Chemistry. 284: 12585-12592. PMID 19129182 DOI: 10.1074/jbc.X800017200  1
2009 Gonzalez MD, Beckwith J. Divisome under construction: Distinct domains of the small membrane protein ftsb are necessary for interaction with multiple cell division proteins Journal of Bacteriology. 191: 2815-2825. DOI: 10.1128/JB.01597-08  1
2008 Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Molecular Cell. 31: 896-908. PMID 18922471 DOI: 10.1016/j.molcel.2008.08.028  1
2008 Dutton RJ, Boyd D, Berkmen M, Beckwith J. Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation Proceedings of the National Academy of Sciences of the United States of America. 105: 11933-11938. PMID 18695247 DOI: 10.1073/pnas.0804621105  1
2008 Robichon C, King GF, Goehring NW, Beckwith J. Artificial septal targeting of Bacillus subtilis cell division proteins in Escherichia coli: an interspecies approach to the study of protein-protein interactions in multiprotein complexes. Journal of Bacteriology. 190: 6048-59. PMID 18621900 DOI: 10.1128/JB.00462-08  1
2008 Faulkner MJ, Veeravalli K, Gon S, Georgiou G, Beckwith J. Functional plasticity of a peroxidase allows evolution of diverse disulfide-reducing pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 6735-40. PMID 18456836 DOI: 10.1073/pnas.0801986105  1
2008 Yamamoto Y, Ritz D, Planson AG, Jönsson TJ, Faulkner MJ, Boyd D, Beckwith J, Poole LB. Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity. Molecular Cell. 29: 36-45. PMID 18206967 DOI: 10.1016/j.molcel.2007.11.029  1
2008 Beckwith J, Morris CA. Twin studies of political behavior: Untenable assumptions? Perspectives On Politics. 6: 785-791. DOI: 10.1017/S1537592708081917  1
2008 Veeravalli K, Faulkner M, Chrysostomou C, Beckwith J, Georgiou G. Investigating the status of oxidative protein folding in escherichia coli missing components of the thiol-redox pathways Aiche Annual Meeting, Conference Proceedings 1
2007 Beckwith J, Morris C. Misreading Dr. Venter's genome [4] Science. 318: 1550. PMID 18063771  1
2007 Ye J, Cho SH, Fuselier J, Li W, Beckwith J, Rapoport TA. Crystal structure of an unusual thioredoxin protein with a zinc finger domain. The Journal of Biological Chemistry. 282: 34945-51. PMID 17913712 DOI: 10.1074/jbc.M704044200  1
2007 Scheffers DJ, Robichon C, Haan GJ, Den Blaauwen T, Koningstein G, Van Bloois E, Beckwith J, Luirink J. Contribution of the FtsQ transmembrane segment to localization to the cell division site Journal of Bacteriology. 189: 7273-7280. PMID 17693520 DOI: 10.1128/JB.00723-07  1
2007 Cho SH, Porat A, Ye J, Beckwith J. Redox-active cysteines of a membrane electron transporter DsbD show dual compartment accessibility Embo Journal. 26: 3509-3520. PMID 17641688 DOI: 10.1038/sj.emboj.7601799  1
2007 Beckwith J. What lies beyond Uranus?: Preconceptions, ignorance, serendipity and suppressors in the search for biology's secrets Genetics. 176: 733-740. PMID 17579239 DOI: 10.1534/genetics.107.076240  1
2007 Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Molecular Cell. 26: 511-21. PMID 17531810 DOI: 10.1016/j.molcel.2007.05.002  1
2007 Porat A, Lillig CH, Johansson C, Fernandes AP, Nilsson L, Holmgren A, Beckwith J. The reducing activity of glutaredoxin 3 toward cytoplasmic substrate proteins is restricted by methionine 43. Biochemistry. 46: 3366-77. PMID 17305371 DOI: 10.1021/bi6024353  1
2007 Goehring NW, Robichon C, Beckwith J. Role for the nonessential N terminus of FtsN in divisome assembly. Journal of Bacteriology. 189: 646-9. PMID 17071748 DOI: 10.1128/JB.00992-06  1
2007 Goehring NW, Petrovska I, Boyd D, Beckwith J. Mutants, suppressors, and wrinkled colonies: mutant alleles of the cell division gene ftsQ point to functional domains in FtsQ and a role for domain 1C of FtsA in divisome assembly. Journal of Bacteriology. 189: 633-45. PMID 16980443 DOI: 10.1128/JB.00991-06  1
2006 Huber D, Beckwith J. Phage display extends its reach. Nature Biotechnology. 24: 793-4. PMID 16841063 DOI: 10.1038/nbt0706-793  1
2006 Goehring NW, Gonzalez MD, Beckwith J. Premature targeting of cell division proteins to midcell reveals hierarchies of protein interactions involved in divisome assembly. Molecular Microbiology. 61: 33-45. PMID 16824093 DOI: 10.1111/j.1365-2958.2006.05206.x  1
2006 Cho SH, Beckwith J. Mutations of the membrane-bound disulfide reductase DsbD that block electron transfer steps from cytoplasm to periplasm in Escherichia coli Journal of Bacteriology. 188: 5066-5076. PMID 16816179 DOI: 10.1128/JB.00368-06  1
2006 Gon S, Beckwith J. Ribonucleotide reductases: Influence of environment on synthesis and activity Antioxidants and Redox Signaling. 8: 773-780. PMID 16771669 DOI: 10.1089/ars.2006.8.773  1
2006 Gon S, Faulkner MJ, Beckwith J. In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli. Antioxidants & Redox Signaling. 8: 735-42. PMID 16771665 DOI: 10.1089/ars.2006.8.735  1
2006 Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J. A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli. The Embo Journal. 25: 1137-47. PMID 16482221 DOI: 10.1038/sj.emboj.7600990  1
2006 Segatori L, Murphy L, Arredondo S, Kadokura H, Gilbert H, Beckwith J, Georgiou G. Conserved role of the linker alpha-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB. The Journal of Biological Chemistry. 281: 4911-9. PMID 16280324 DOI: 10.1074/jbc.M505453200  1
2006 Beckwith J, Geller L, Hall MA. Informed Consent Genetic Testing: Care, Consent, and Liability. 128-162. DOI: 10.1002/0471748897.ch7  1
2005 Huber D, Cha MI, Debarbieux L, Planson AG, Cruz N, López G, Tasayco ML, Chaffotte A, Beckwith J. A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 18872-7. PMID 16357193 DOI: 10.1073/pnas.0509583102  1
2005 Beckwith J, Huang F. Should we make a fuss? A case for social responsibility in science Nature Biotechnology. 23: 1479-1480. PMID 16333283 DOI: 10.1038/nbt1205-1479  1
2005 Goehring NW, Beckwith J. Diverse paths to midcell: assembly of the bacterial cell division machinery. Current Biology : Cb. 15: R514-26. PMID 16005287 DOI: 10.1016/j.cub.2005.06.038  1
2005 Sevier CS, Kadokura H, Tam VC, Beckwith J, Fass D, Kaiser CA. The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases. Protein Science : a Publication of the Protein Society. 14: 1630-42. PMID 15930008 DOI: 10.1110/ps.051355705  1
2005 Huber D, Boyd D, Xia Y, Olma MH, Gerstein M, Beckwith J. Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation Journal of Bacteriology. 187: 2983-2991. PMID 15838024 DOI: 10.1128/JB.187.9.2983-2991.2005  1
2005 Kadokura H, Nichols L, Beckwith J. Mutational alterations of the key cis proline residue that cause accumulation of enzymatic reaction intermediates of DsbA, a member of the thioredoxin superfamily Journal of Bacteriology. 187: 1519-1522. PMID 15687218 DOI: 10.1128/JB.187.4.1519-1522.2005  1
2005 Berkmen M, Boyd D, Beckwith J. The nonconsecutive disulfide bond of Escherichia coli phytase (AppA) renders it dependent on the protein-disulfide isomerase, DsbC Journal of Biological Chemistry. 280: 11387-11394. PMID 15642731 DOI: 10.1074/jbc.M411774200  1
2005 Goehring NW, Gueiros-Filho F, Beckwith J. Premature targeting of a cell division protein to midcell allows dissection of divisome assembly in Escherichia coli. Genes & Development. 19: 127-37. PMID 15630023 DOI: 10.1101/gad.1253805  1
2005 Or E, Boyd D, Gon S, Beckwith J, Rapoport T. The bacterial ATPase SecA functions as a monomer in protein translocation Journal of Biological Chemistry. 280: 9097-9105. PMID 15618215 DOI: 10.1074/jbc.M413947200  1
2004 Schaechter M, The View From Here Group. Escherichia coli and Salmonella 2000: the View From Here. Ecosal Plus. 1. PMID 26443369 DOI: 10.1128/ecosalplus.1.4  1
2004 Porat A, Cho SH, Beckwith J. The unusual transmembrane electron transporter DsbD and its homologues: A bacterial family of disulfide reductases Research in Microbiology. 155: 617-622. PMID 15380548 DOI: 10.1016/j.resmic.2004.05.005  1
2004 Buddelmeijer N, Beckwith J. A complex of the Escherichia coli cell division proteins FtsL, FtsB and FtsQ forms independently of its localization to the septal region Molecular Microbiology. 52: 1315-1327. PMID 15165235 DOI: 10.1111/j.1365-2958.2004.04044.x  1
2004 Ortenberg R, Gon S, Porat A, Beckwith J. Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 101: 7439-7444. PMID 15123823 DOI: 10.1073/pnas.0401965101  1
2004 Kadokura H, Tian H, Zander T, Bardwell JCA, Beckwith J. Snapshots of DsbA in Action: Detection of Proteins in the Process of Oxidative Folding Science. 303: 534-537. PMID 14739460 DOI: 10.1126/science.1091724  1
2004 Belin D, Guzman LM, Bost S, Konakova M, Silva F, Beckwith J. Functional activity of eukaryotic signal sequences in Escherichia coli: the ovalbumin family of serine protease inhibitors. Journal of Molecular Biology. 335: 437-53. PMID 14672654 DOI: 10.1016/j.jmb.2003.10.076  1
2003 Brandon LD, Goehring N, Janakiraman A, Yan AW, Wu T, Beckwith J, Goldberg MB. IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed. Molecular Microbiology. 50: 45-60. PMID 14507362 DOI: 10.1046/j.1365-2958.2003.03674.x  1
2003 Ortenberg R, Beckwith J. Functions of thiol-disulfide oxidoreductases in E. coli: Redox myths, realities, and practicalities Antioxidants and Redox Signaling. 5: 403-411. PMID 13678528  1
2003 Schierle CF, Berkmen M, Huber D, Kumamoto C, Boyd D, Beckwith J. The DsbA signal sequence directs efficient, cotranslational export of passenger proteins to the Escherichia coli periplasm via the signal recognition particle pathway. Journal of Bacteriology. 185: 5706-13. PMID 13129941 DOI: 10.1128/JB.185.19.5706-5713.2003  1
2003 Katzen F, Beckwith J. Role and location of the unusual redox-active cysteines in the hydrophobic domain of the transmembrane electron transporter DsbD Proceedings of the National Academy of Sciences of the United States of America. 100: 10471-10476. PMID 12925743 DOI: 10.1073/pnas.1334136100  1
2003 Toutain CM, Clarke DJ, Leeds JA, Kuhn J, Beckwith J, Holland IB, Jacq A. The transmembrane domain of the DnaJ-like protein DjlA is a dimerisation domain Molecular Genetics and Genomics. 268: 761-770. PMID 12655402  1
2003 Kadokura H, Katzen F, Beckwith J. Protein disulfide bond formation in prokaryotes Annual Review of Biochemistry. 72: 111-135. PMID 12524212 DOI: 10.1146/annurev.biochem.72.121801.161459  1
2002 Buddelmeijer N, Beckwith J. Assembly of cell division proteins at the E. coli cell center Current Opinion in Microbiology. 5: 553-557. PMID 12457697 DOI: 10.1016/S1369-5274(02)00374-0  1
2002 Haebel PW, Goldstone D, Katzen F, Beckwith J, Metcalf P. The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: Crystal structure of the DsbC-DsbDα complex Embo Journal. 21: 4774-4784. PMID 12234918 DOI: 10.1093/emboj/cdf489  1
2002 Katzen F, Deshmukh M, Daldal F, Beckwith J. Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD. The Embo Journal. 21: 3960-9. PMID 12145197 DOI: 10.1093/emboj/cdf405  1
2002 Jurado P, Ritz D, Beckwith J, De Lorenzo V, Fernández LA. Production of functional single-chain Fv antibodies in the cytoplasm of Escherichia coli Journal of Molecular Biology. 320: 1-10. PMID 12079330 DOI: 10.1016/S0022-2836(02)00405-9  1
2002 Kadokura H, Beckwith J. Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA Embo Journal. 21: 2354-2363. PMID 12006488 DOI: 10.1093/emboj/21.10.2354  1
2002 Buddelmeijer N, Judson N, Boyd D, Mekalanos JJ, Beckwith J. YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site. Proceedings of the National Academy of Sciences of the United States of America. 99: 6316-21. PMID 11972052 DOI: 10.1073/pnas.092128499  1
2002 Ritz D, Beckwith J. Redox state of cytoplasmic thioredoxin Methods in Enzymology. 347: 360-370. PMID 11898427 DOI: 10.1016/S0076-6879(02)47036-X  1
2002 Katzen F, Beckwith J. Disulfide bond formation in periplasm of Escherichia coli Methods in Enzymology. 348: 54-66. PMID 11885294 DOI: 10.1016/S0076-6879(02)48626-0  1
2002 Chen JC, Minev M, Beckwith J. Analysis of ftsQ mutant alleles in Escherichia coli: Complementation, septal localization, and recruitment of downstream cell division proteins Journal of Bacteriology. 184: 695-705. PMID 11790739  1
2002 Tian H, Beckwith J. Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway Journal of Bacteriology. 184: 111-118. PMID 11741850 DOI: 10.1128/JB.184.1.111-118.2002  1
2001 Beckwith J. On the social responsibility of scientists Annali Dell'Istituto Superiore Di Sanita. 37: 189-194. PMID 11758276  1
2001 Kadokura H, Beckwith J. The expanding world of oxidative protein folding Nature Cell Biology. 3: E247-E249. PMID 11715032  1
2001 Chen JC, Beckwith J. FtsQ, FtsL and Ftsl require FtsK, but not FtsN, for co-localization with FtsZ during Escherichia coli cell division Molecular Microbiology. 42: 395-413. PMID 11703663 DOI: 10.1046/j.1365-2958.2001.02640.x  1
2001 Leeds JA, Boyd D, Huber DR, Sonoda GK, Luu HT, Engelman DM, Beckwith J. Genetic selection for and molecular dynamic modeling of a protein transmembrane domain multimerization motif from a random Escherichia coli genomic library. Journal of Molecular Biology. 313: 181-95. PMID 11601855 DOI: 10.1006/jmbi.2001.5007  1
2001 Ritz D, Lim J, Reynolds CM, Poole LB, Beckwith J. Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion. Science (New York, N.Y.). 294: 158-60. PMID 11588261 DOI: 10.1126/science.1063143  1
2001 Ritz D, Beckwith J. Roles of thiol-redox pathways in bacteria Annual Review of Microbiology. 55: 21-48. PMID 11544348 DOI: 10.1146/annurev.micro.55.1.21  1
2001 Goldstone D, Haebel PW, Katzen F, Bader MW, Bardwell JCA, Beckwith J, Metcalf P. DsbC activation by the N-terminal domain of DsbD Proceedings of the National Academy of Sciences of the United States of America. 98: 9551-9556. PMID 11493705 DOI: 10.1073/pnas.171315498  1
2000 Katzen F, Beckwith J. Transmembrane electron transfer by the membrane protein DsbD occurs via a disulfide bond cascade Cell. 103: 769-779. PMID 11114333  1
2000 Leeds JA, Beckwith J. A gene fusion method for assaying interactions of protein transmembrane segments in vivo Methods in Enzymology. 327: 165-175. PMID 11044981 DOI: 10.1016/S0076-6879(00)27274-1  1
1996 De La Paz MA, Zhang J, Fridovich I. Antioxidant enzymes of the human retina: effect of age on enzyme activity of macula and periphery. Current Eye Research. 15: 273-8. PMID 8654107 DOI: 10.1002/9780470177334.ch3  1
1990 Davis BD. The human genome and other initiatives. Science (New York, N.Y.). 249: 342-3. PMID 2377887  1
1985 Silhavy TJ, Beckwith JR. Uses of lac fusions for the study of biological problems. Microbiological Reviews. 49: 398-418. PMID 3005818  1
1984 Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR. D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport. Journal of Bacteriology. 158: 665-73. PMID 6327616  1
1981 Ito K, Beckwith JR. Role of the mature protein sequence of maltose-binding protein in its secretion across the E. coli cytoplasmic membrane. Cell. 25: 143-50. PMID 7023692 DOI: 10.1016/0092-8674(81)90238-5  1
1980 Welply JK, Fowler AV, Beckwith JR, Zabin I. Positions of early nonsense and deletion mutations in lacZ. Journal of Bacteriology. 142: 732-4. PMID 6769904  1
1980 Shuman HA, Silhavy TJ, Beckwith JR. Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system. The Journal of Biological Chemistry. 255: 168-74. PMID 6765939  1
1979 Silhavy TJ, Brickman E, Bassford PJ, Casadaban MJ, Shuman HA, Schwartz V, Guarente L, Schwartz M, Beckwith JR. Structure of the malB region in Escherichia coli K12. II. Genetic map of the malE,F,G operon. Molecular & General Genetics : Mgg. 174: 249-59. PMID 384167 DOI: 10.1007/BF00267797  1
1979 Bassford PJ, Silhavy TJ, Beckwith JR. Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm. Journal of Bacteriology. 139: 19-31. PMID 110778  1
1979 Brickman E, Silhavy TJ, Bassford PJ, Shuman HA, Beckwith JR. Sites within gene lacZ of Escherichia coli for formation of active hybrid beta-galactosidase molecules. Journal of Bacteriology. 139: 13-8. PMID 110776  1
1978 Zabin I, Fowler AV, Beckwith JR. Position of the mutation in beta-galactosidase ochre mutant U118. Journal of Bacteriology. 133: 437-8. PMID 412841  1
1976 Silhavy TJ, Casadaban MJ, Shuman HA, Beckwith JR. Conversion of beta-galactosidase to a membrane-bound state by gene fusion. Proceedings of the National Academy of Sciences of the United States of America. 73: 3423-7. PMID 790385  1
1975 Mitchell DH, Reznikoff WS, Beckwith JR. Genetic fusions defining trp and lac operon regulatory elements. Journal of Molecular Biology. 93: 331-50. PMID 1095760 DOI: 10.1016/0022-2836(75)90281-8  1
1971 Ippen K, Shapiro JA, Beckwith JR. Transposition of the lac region to the gal region of the Escherichia coli chromosome: isolation of lambda-lac transducing bacteriophages. Journal of Bacteriology. 108: 5-9. PMID 4941573  1
1971 Eron L, Arditti R, Zubay G, Connaway S, Beckwith JR. An adenosine 3':5'-cyclic monophosphate-binding protein that acts on the transcription process. Proceedings of the National Academy of Sciences of the United States of America. 68: 215-8. PMID 4322261  1
1970 Miller JH, Reznikoff WS, Silverstone AE, Ippen K, Signer ER, Beckwith JR. Fusions of the lac and trp Regions of the Escherichia coli Chromosome. Journal of Bacteriology. 104: 1273-9. PMID 16559103  1
1969 Gottesman S, Beckwith JR. Directed transposition of the arabinose operon: a technique for the isolation of specialized transducing bacteriophages for any Escherichia coli gene. Journal of Molecular Biology. 44: 117-27. PMID 4897798  1
1969 Reznikoff WS, Beckwith JR. Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli. Journal of Molecular Biology. 43: 215-8. PMID 4897792  1
1969 Reznikoff WS, Miller JH, Scaife JG, Beckwith JR. A mechanism for repressor action. Journal of Molecular Biology. 43: 201-13. PMID 4897791  1
1969 Schwartz DO, Beckwith JR. Mutagens which cause deletions in Escherichia coli. Genetics. 61: 371-6. PMID 4896998  1
1969 Silverstone AE, Magasanik B, Reznikoff WS, Miller JH, Beckwith JR. Catabolite sensitive site of the lac operon. Nature. 221: 1012-4. PMID 4886742 DOI: 10.1038/2211012b0  1
1968 Ohlsson BM, Strigini PF, Beckwith JR. Allelic amber and ochre suppressors. Journal of Molecular Biology. 36: 209-18. PMID 5760539  1
1968 Arditti RR, Scaife JG, Beckwith JR. The nature of mutants in the lac promoter region. Journal of Molecular Biology. 38: 421-6. PMID 4887878  1
1968 Miller JH, Ippen K, Scaife JG, Beckwith JR. The promoter-operator region of the lac operon of Escherichia coli. Journal of Molecular Biology. 38: 413-20. PMID 4887877  1
1967 Beckwith JR. Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model. Science (New York, N.Y.). 156: 597-604. PMID 5337175  1
1966 Fox CF, Beckwith JR, Epstein W, Signer ER. Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism. Journal of Molecular Biology. 19: 576-9. PMID 5338859  1
1966 Beckwith JR, Signer ER. Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80. Journal of Molecular Biology. 19: 254-65. PMID 5338856  1
1966 Scaife J, Beckwith JR. Mutational alteration of the maximal level of Lac operon expression. Cold Spring Harbor Symposia On Quantitative Biology. 31: 403-8. PMID 4866390  1
1966 Beckwith JR, Signer ER, Epstein W. Transposition of the Lac region of E. coli. Cold Spring Harbor Symposia On Quantitative Biology. 31: 393-401. PMID 4866389  1
1966 Signer ER, Beckwith JR. Transposition of the lac region of Escherichia coli. III. The mechanism of attachment of bacteriophage φ80 to the bacterial chromosome Journal of Molecular Biology. 22: 33-51.  1
1965 Newton WA, Beckwith JR, Zipser D, Brenner S. Nonsense mutants and polarity in the lac operon of Escherichia coli. Journal of Molecular Biology. 14: 290-6. PMID 5327654  1
1965 Signer ER, Beckwith JR, Brenner S. Mapping of suppressor loci in Escherichia coli. Journal of Molecular Biology. 14: 153-66. PMID 5327649  1
1964 TAYLOR AL, BECKWITH JR, PARDEE AB, AUSTRIAN R, JACOB F. THE CHROMOSOMAL LOCATION OF THE STRUCTURAL GENE FOR OROTIDYLIC ACID PYROPHOSPHORYLASE IN ESCHERICHIA COLI. Journal of Molecular Biology. 8: 771. PMID 14187401  1
1964 BECKWITH JR. A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI. Journal of Molecular Biology. 8: 427-30. PMID 14168696  1
1963 BECKWITH JR, HAGER LP. BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN. The Journal of Biological Chemistry. 238: 3091-4. PMID 14081930  1
1963 BECKWITH JR, CLARK R, HAGER LP. BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN. The Journal of Biological Chemistry. 238: 3086-90. PMID 14081929  1
1962 PARDEE AB, BECKWITH JR. Genetic determination of constitutive enzyme levels. Biochimica Et Biophysica Acta. 60: 452-4. PMID 14483809  1
1962 BECKWITH JR, PARDEE AB, AUSTRIAN R, JACOB F. Coordination of the synthesis of the enzymes in the pyrimidine pathway of E. coli. Journal of Molecular Biology. 5: 618-34. PMID 13970180  1
1961 Beckwith JR, Hager LP. Synthesis of D,L-caldariomycin Journal of Organic Chemistry. 26: 5206-5208.  1
1959 SHAW PD, BECKWITH JR, HAGER LP. Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid. The Journal of Biological Chemistry. 234: 2560-4. PMID 14445651  1
1955 WOOD JE, BECKWITH JR, CAMP JL. Treatment of coronary thrombosis with myocardial infarction. Journal of the American Medical Association. 159: 635-8. PMID 13263101 DOI: 10.1001/jama.1955.02960240001001  0.01
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