John D. Sutherland, Ph.D. - Publications

Affiliations: 
Chemistry MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
Website:
http://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/john-sutherland/

78/216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Su M, Schmitt C, Liu Z, Roberts SJ, Liu KC, Röder K, Jäschke A, Wales DJ, Sutherland JD. Triplet-Encoded Prebiotic RNA Aminoacylation. Journal of the American Chemical Society. PMID 37435826 DOI: 10.1021/jacs.3c03931  0.549
2022 Wu LF, Liu Z, Roberts SJ, Su M, Szostak JW, Sutherland JD. Template-Free Assembly of Functional RNAs by Loop-Closing Ligation. Journal of the American Chemical Society. 144: 13920-13927. PMID 35880790 DOI: 10.1021/jacs.2c05601  0.649
2022 Roberts SJ, Liu Z, Sutherland JD. Potentially Prebiotic Synthesis of Aminoacyl-RNA via a Bridging Phosphoramidate-Ester Intermediate. Journal of the American Chemical Society. PMID 35230111 DOI: 10.1021/jacs.2c00772  0.326
2021 Xu J, Green NJ, Russell DA, Liu Z, Sutherland JD. Prebiotic Photochemical Coproduction of Purine Ribo- and Deoxyribonucleosides. Journal of the American Chemical Society. PMID 34469129 DOI: 10.1021/jacs.1c07403  0.335
2021 Wu LF, Su M, Liu Z, Bjork SJ, Sutherland JD. Interstrand Aminoacyl Transfer in a tRNA Acceptor Stem-Overhang Mimic. Journal of the American Chemical Society. PMID 34283595 DOI: 10.1021/jacs.1c05746  0.531
2021 Rimmer PB, Thompson SJ, Xu J, Russell DA, Green NJ, Ritson DJ, Sutherland JD, Queloz DP. Timescales for Prebiotic Photochemistry Under Realistic Surface Ultraviolet Conditions. Astrobiology. PMID 34152196 DOI: 10.1089/ast.2020.2335  0.681
2020 Xu J, Chmela V, Green NJ, Russell DA, Janicki MJ, Góra RW, Szabla R, Bond AD, Sutherland JD. Selective prebiotic formation of RNA pyrimidine and DNA purine nucleosides. Nature. 582: 60-66. PMID 32494078 DOI: 10.1038/s41586-020-2330-9  0.683
2019 Polyansky AA, Kreuter M, Sutherland JD, Zagrovic B. Direct interplay between stereochemistry and conformational preferences in aminoacylated oligoribonucleotides. Nucleic Acids Research. PMID 31612955 DOI: 10.1093/Nar/Gkz902  0.315
2019 Xu J, Green NJ, Gibard C, Krishnamurthy R, Sutherland JD. Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction. Nature Chemistry. PMID 30936523 DOI: 10.1038/S41557-019-0225-X  0.442
2019 Bonfio C, Caumes C, Duffy CD, Patel BH, Percivalle C, Tsanakopoulou M, Sutherland JD. Length-selective synthesis of acylglycerol-phosphates through energy-dissipative cycling. Journal of the American Chemical Society. PMID 30767518 DOI: 10.1021/Jacs.8B12331  0.34
2018 Rimmer PB, Xu J, Thompson SJ, Gillen E, Sutherland JD, Queloz D. The origin of RNA precursors on exoplanets. Science Advances. 4. PMID 33276319 DOI: 10.1126/sciadv.aar3302  0.691
2018 Mariani A, Bonfio C, Johnson CM, Sutherland JD. pH-Driven RNA strand separation under prebiotically plausible conditions. Biochemistry. PMID 30383375 DOI: 10.1021/Acs.Biochem.8B01080  0.388
2018 Liu Z, Mariani A, Wu L, Ritson D, Folli A, Murphy D, Sutherland J. Tuning the reactivity of nitriles using Cu(ii) catalysis - potentially prebiotic activation of nucleotides. Chemical Science. 9: 7053-7057. PMID 30310625 DOI: 10.1039/C8Sc02513D  0.304
2018 Rimmer PB, Xu J, Thompson SJ, Gillen E, Sutherland JD, Queloz D. The origin of RNA precursors on exoplanets. Science Advances. 4: eaar3302. PMID 30083602 DOI: 10.1126/Sciadv.Aar3302  0.706
2018 Mariani A, Russell DA, Javelle T, Sutherland JD. A Light-Releasable Potentially Prebiotic Nucleotide Activating Agent. Journal of the American Chemical Society. PMID 29965757 DOI: 10.1021/Jacs.8B05189  0.303
2018 Ritson DJ, Battilocchio C, Ley SV, Sutherland JD. Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry. Nature Communications. 9: 1821. PMID 29739945 DOI: 10.1038/S41467-018-04147-2  0.317
2017 Bonfio C, Valer L, Scintilla S, Shah S, Evans DJ, Jin L, Szostak JW, Sasselov DD, Sutherland JD, Mansy SS. UV-light-driven prebiotic synthesis of iron-sulfur clusters. Nature Chemistry. 9: 1229-1234. PMID 29168482 DOI: 10.1038/Nchem.2817  0.449
2017 Tsanakopoulou M, Sutherland JD. Cyanamide as a prebiotic phosphate activating agent - catalysis by simple 2-oxoacid salts. Chemical Communications (Cambridge, England). PMID 29043309 DOI: 10.1039/C7Cc07517K  0.328
2017 Mariani A, Sutherland JD. Non-Enzymatic RNA Backbone Proofreading through Energy-Dissipative Recycling. Angewandte Chemie (International Ed. in English). PMID 28467695 DOI: 10.1002/Anie.201703169  0.393
2017 Xu J, Tsanakopoulou M, Magnani CJ, Szabla R, Šponer JE, Šponer J, Góra RW, Sutherland JD. A prebiotically plausible synthesis of pyrimidine β-ribonucleosides and their phosphate derivatives involving photoanomerization. Nature Chemistry. 9: 303-309. PMID 28338689 DOI: 10.1038/Nchem.2664  0.338
2016 Liu Z, Rigger L, Rossi JC, Sutherland JD, Pascal R. Mixed Anhydride Intermediates in the Reaction of 5(4H)-Oxazolones with Phosphate Esters and Nucleotides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27534830 DOI: 10.1002/Chem.201602697  0.373
2016 Ritson D, Sutherland J, Xu J. Thiophosphate – A Versatile Prebiotic Reagent? Synlett. 28: 64-67. DOI: 10.1055/S-0036-1589414  0.312
2016 Liu Z, Rigger L, Rossi J, Sutherland JD, Pascal R. Inside Cover: Mixed Anhydride Intermediates in the Reaction of 5(4H )-Oxazolones with Phosphate Esters and Nucleotides (Chem. Eur. J. 42/2016) Chemistry - a European Journal. 22: 14758-14758. DOI: 10.1002/Chem.201603523  0.304
2015 Patel BH, Percivalle C, Ritson DJ, Duffy CD, Sutherland JD. Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism. Nature Chemistry. 7: 301-7. PMID 25803468 DOI: 10.1038/Nchem.2202  0.356
2014 Ritson DJ, Sutherland JD. Conversion of biosynthetic precursors of RNA to those of DNA by photoredox chemistry. Journal of Molecular Evolution. 78: 245-50. PMID 24736972 DOI: 10.1007/s00239-014-9617-0  0.305
2014 Xu J, Duffy CD, Chan CK, Sutherland JD. Solid-phase synthesis and hybrization behavior of partially 2'/3'-O-acetylated RNA oligonucleotides. The Journal of Organic Chemistry. 79: 3311-26. PMID 24666354 DOI: 10.1021/Jo5002824  0.352
2013 Ritson DJ, Sutherland JD. Synthesis of aldehydic ribonucleotide and amino acid precursors by photoredox chemistry. Angewandte Chemie (International Ed. in English). 52: 5845-7. PMID 23610046 DOI: 10.1002/Anie.201300321  0.362
2013 Bowler FR, Chan CK, Duffy CD, Gerland B, Islam S, Powner MW, Sutherland JD, Xu J. Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation. Nature Chemistry. 5: 383-9. PMID 23609088 DOI: 10.1038/Nchem.1626  0.595
2013 Islam S, Aguilar JA, Powner MW, Nilsson M, Morris GA, Sutherland JD. Detection of potential TNA and RNA nucleoside precursors in a prebiotic mixture by pure shift diffusion-ordered NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 4586-95. PMID 23371787 DOI: 10.1002/Chem.201202649  0.545
2012 Ritson D, Sutherland JD. Prebiotic synthesis of simple sugars by photoredox systems chemistry. Nature Chemistry. 4: 895-9. PMID 23089863 DOI: 10.1038/Nchem.1467  0.353
2011 Powner MW, Sutherland JD. Prebiotic chemistry: a new modus operandi. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2870-7. PMID 21930577 DOI: 10.1098/Rstb.2011.0134  0.333
2011 Lilley DM, Sutherland J. The chemical origins of life and its early evolution: an introduction. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2853-6. PMID 21930575 DOI: 10.1098/Rstb.2011.0133  0.422
2011 Powner MW, Sutherland JD, Szostak JW. The origins of nucleotides Synlett. 1956-1964. DOI: 10.1055/S-0030-1261177  0.539
2011 Powner MW, Sutherland JD, Szostak JW. Chemoselective multicomponent one-pot assembly of purine precursors in water (Journal of the American Chemical Society (2010) 132 (16677-16688) DOI:10.1021/ja108197s) Journal of the American Chemical Society. 133: 4149-4150. DOI: 10.1021/ja2002023  0.382
2010 Powner MW, Sutherland JD, Szostak JW. Chemoselective multicomponent one-pot assembly of purine precursors in water. Journal of the American Chemical Society. 132: 16677-88. PMID 21043502 DOI: 10.1021/Ja108197S  0.603
2010 Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A stereoelectronic effect in prebiotic nucleotide synthesis. Acs Chemical Biology. 5: 655-7. PMID 20499895 DOI: 10.1021/Cb100093G  0.333
2010 Powner MW, Sutherland JD. Phosphate-mediated interconversion of ribo- and arabino-configured prebiotic nucleotide intermediates. Angewandte Chemie (International Ed. in English). 49: 4641-3. PMID 20491113 DOI: 10.1002/Anie.201001662  0.3
2010 Sutherland JD. Ribonucleotides. Cold Spring Harbor Perspectives in Biology. 2: a005439. PMID 20452951 DOI: 10.1101/cshperspect.a005439  0.31
2009 Powner MW, Gerland B, Sutherland JD. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. Nature. 459: 239-42. PMID 19444213 DOI: 10.1038/Nature08013  0.433
2008 Anastasi C, Buchet FF, Crowe MA, Helliwell M, Raftery J, Sutherland JD. The search for a potentially prebiotic synthesis of nucleotides via arabinose-3-phosphate and its cyanamide derivative. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 2375-88. PMID 18203227 DOI: 10.1002/Chem.200701351  0.582
2008 Sutherland JD, Mullen LB, Buchet FF. Potentially prebiotic passerini-type reactions of phosphates Synlett. 2161-2163. DOI: 10.1055/S-2008-1078018  0.753
2007 Mullen LB, Sutherland JD. Simultaneous nucleotide activation and synthesis of amino acid amides by a potentially prebiotic multi-component reaction. Angewandte Chemie (International Ed. in English). 46: 8063-6. PMID 17854015 DOI: 10.1002/Anie.200702870  0.759
2007 Powner MW, Anastasi C, Crowe MA, Parkes AL, Raftery J, Sutherland JD. On the prebiotic synthesis of ribonucleotides: photoanomerisation of cytosine nucleosides and nucleotides revisited. Chembiochem : a European Journal of Chemical Biology. 8: 1170-9. PMID 17549787 DOI: 10.1002/Cbic.200700098  0.534
2007 Mullen LB, Sutherland JD. Formation of potentially prebiotic amphiphiles by reaction of beta-hydroxy-n-alkylamines with cyclotriphosphate. Angewandte Chemie (International Ed. in English). 46: 4166-8. PMID 17457789 DOI: 10.1002/Anie.200700394  0.735
2007 Anastasi C, Buchet FF, Crowe MA, Parkes AL, Powner MW, Smith JM, Sutherland JD. RNA: prebiotic product, or biotic invention? Chemistry & Biodiversity. 4: 721-39. PMID 17443885 DOI: 10.1002/Cbdv.200790060  0.566
2007 Sutherland JD. Looking beyond the RNA structural neighborhood for potentially primordial genetic systems. Angewandte Chemie (International Ed. in English). 46: 2354-6. PMID 17285673 DOI: 10.1002/Anie.200604374  0.324
2007 Anastasi C, Crowe MA, Sutherland JD. Two-step potentially prebiotic synthesis of alpha-d-cytidine-5'-phosphate from d-glyceraldehyde-3-phosphate. Journal of the American Chemical Society. 129: 24-5. PMID 17199270 DOI: 10.1021/Ja066495V  0.545
2006 Anastasi C, Crowe MA, Powner MW, Sutherland JD. Direct assembly of nucleoside precursors from two- and three-carbon units. Angewandte Chemie (International Ed. in English). 45: 6176-9. PMID 16917794 DOI: 10.1002/Anie.200601267  0.445
2006 Crowe MA, Sutherland JD. Reaction of cytidine nucleotides with cyanoacetylene: support for the intermediacy of nucleoside-2',3'-cyclic phosphates in the prebiotic synthesis of RNA. Chembiochem : a European Journal of Chemical Biology. 7: 951-6. PMID 16642527 DOI: 10.1002/Cbic.200600024  0.57
2005 Saewan N, Crowe MA, Helliwell M, Raftery J, Chantrapromma K, Sutherland JD. Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 4th Communication. Further observations concerning pyrimidine nucleoside synthesis by stepwise nucleobase assembly. Chemistry & Biodiversity. 2: 66-83. PMID 17191920 DOI: 10.1002/Cbdv.200490167  0.534
2004 Borsenberger V, Crowe MA, Lehbauer J, Raftery J, Helliwell M, Bhutia K, Cox T, Sutherland JD. Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. Chemistry & Biodiversity. 1: 203-46. PMID 17191842 DOI: 10.1002/Cbdv.200490020  0.548
2004 Ace K, Sutherland JD. Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives. Chemistry & Biodiversity. 1: 1678-93. PMID 17191808 DOI: 10.1002/Cbdv.200490126  0.38
2004 Smith JM, Borsenberger V, Raftery J, Sutherland JD. Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 2nd communication. Derivation and reactivity of xylose phosphates. Chemistry & Biodiversity. 1: 1418-51. PMID 17191788 DOI: 10.1002/Cbdv.200490105  0.379
2003 Ingar AA, Luke RW, Hayter BR, Sutherland JD. Synthesis of cytidine ribonucleotides by stepwise assembly of the heterocycle on a sugar phosphate. Chembiochem : a European Journal of Chemical Biology. 4: 504-7. PMID 12794860 DOI: 10.1002/Cbic.200300554  0.451
2002 Day YS, Bacon SL, Hughes-Thomas Z, Blackburn JM, Sutherland JD. Mutational analysis of the kinetics and thermodynamics of transcription factor NF-kappaB homodimerisation. Chembiochem : a European Journal of Chemical Biology. 3: 1192-9. PMID 12465027 DOI: 10.1002/1439-7633(20021202)3:12<1192::Aid-Cbic1192>3.0.Co;2-U  0.557
2002 Culliford SJ, McCauley P, Sutherland AJ, McCairn M, Sutherland J, Blackburn J, Kozlowski RZ. A novel cell-based scintillation proximity assay for studying protein function and activity in vitro using membrane-soluble scintillants. Biochemical and Biophysical Research Communications. 296: 857-863. PMID 12200126 DOI: 10.1016/S0006-291X(02)00944-0  0.529
2001 Speight RE, Hart DJ, Sutherland JD, Blackburn JM. A new plasmid display technology for the in vitro selection of functional phenotype-genotype linked proteins. Chemistry & Biology. 8: 951-65. PMID 11590020 DOI: 10.1016/S1074-5521(01)00066-7  0.558
2001 Hart DJ, Speight RE, Sutherland JD, Blackburn JM. Analysis of the NF-kappaB p50 dimer interface by diversity screening. Journal of Molecular Biology. 310: 563-75. PMID 11439024 DOI: 10.1006/Jmbi.2001.4724  0.548
1999 Hart DJ, Speight RE, Cooper MA, Sutherland JD, Blackburn JM. The salt dependence of DNA recognition by NF-kappaB p50: a detailed kinetic analysis of the effects on affinityand specificity. Nucleic Acids Research. 27: 1063-9. PMID 9927740 DOI: 10.1093/Nar/27.4.1063  0.548
1997 Sutherland JD, Blackburn JM. Killing two birds with one stone: a chemically plausible scheme for linked nucleic acid replication and coded peptide synthesis. Chemistry & Biology. 4: 481-8. PMID 9263634 DOI: 10.1016/S1074-5521(97)90318-5  0.584
1997 Sutherland JD, Whitfield JN. Synthesis of potentially prebiotic RNA precursors: Cytosine and guanine derivatives Tetrahedron Letters. 38: 1451-1454. DOI: 10.1016/S0040-4039(97)00055-5  0.414
1997 Sutherland JD, Whitfield JN. Prebiotic chemistry: A bioorganic perspective Tetrahedron. 53: 11493-11527. DOI: 10.1016/S0040-4020(97)00438-9  0.413
1995 Blackburn JM, Sutherland JD, Baldwin JE. A heuristic approach to the analysis of enzymic catalysis: reaction of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-allylglycine catalyzed by isopenicillin N synthase isozymes. Biochemistry. 34: 7548-62. PMID 7779800 DOI: 10.1021/Bi00022A031  0.625
1995 Tobin MB, Cole SC, Miller JR, Baldwin JE, Sutherland JD. Amino-acid substitutions in the cleavage site of acyl-coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum: effect on proenzyme cleavage and activity. Gene. 162: 29-35. PMID 7557412 DOI: 10.1016/0378-1119(95)00369-H  0.444
1995 Pavey JBJ, Sutherland JD, Weaver GW, Whitfield JN. Synthesis of potentially prebiotic RNA precursors: Adenine and uracil derivatives Tetrahedron Letters. 36: 2657-2660. DOI: 10.1016/0040-4039(95)00326-8  0.404
1994 Tobin MB, Cole SC, Kovacevic S, Miller JR, Baldwin JE, Sutherland JD. Acyl-coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum: effect of amino acid substitutions at Ser227, Ser230 and Ser309 on proenzyme cleavage and activity. Fems Microbiology Letters. 121: 39-46. PMID 8082826 DOI: 10.1111/J.1574-6968.1994.Tb07073.X  0.46
1994 Baldwin JE, Chan RY, Sutherland JD. Novel stereochemical manipulations of the penicillin nucleus Tetrahedron Letters. 35: 5519-5522. DOI: 10.1016/S0040-4039(00)73540-4  0.434
1993 Aplin RT, Baldwin JE, Cole SC, Sutherland JD, Tobin MB. On the production of alpha, beta-heterodimeric acyl-coenzyme A: isopenicillin N-acyltransferase of Penicillium chrysogenum. Studies using a recombinant source. Febs Letters. 319: 166-70. PMID 8384123 DOI: 10.1016/0014-5793(93)80060-8  0.438
1993 Tobin MB, Baldwin JE, Cole SC, Miller JR, Skatrud PL, Sutherland JD. The requirement for subunit interaction in the production of Penicillium chrysogenum acyl-coenzyme A:isopenicillin N acyltransferase in Escherichia coli. Gene. 132: 199-206. PMID 8224864 DOI: 10.1016/0378-1119(93)90196-A  0.445
1993 Lewis ML, Rowe CJ, Sewald N, Sutherland JD, Wilson EJ, Wright MC. The effect of pH on the solution structure of Δ1-pyrroline-2-carboxylic acid as revealed by NMR and electrospray mass spectroscopy Bioorganic and Medicinal Chemistry Letters. 3: 1193-1196. DOI: 10.1016/S0960-894X(00)80313-3  0.465
1993 Lewis ML, Martin SL, Rowe CJ, Sutherland JD, Wilson EJ, Wright MC. Reduction of Δ1-pyrroline-2-carboxylic acid to proline by an escherichia coli proline auxotroph Bioorganic and Medicinal Chemistry Letters. 3: 1189-1192. DOI: 10.1016/S0960-894X(00)80312-1  0.329
1992 Baldwin JE, Blackburn JM, Heath RJ, Sutherland JD. High-level soluble expression and purification of deacetoxycephalosporin C/deacetylcephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 2: 663-668. DOI: 10.1016/S0960-894X(00)80386-8  0.609
1991 Baldwin JE, Martin SL, Sutherland JD. Site-specific forced misincorporation mutagenesis using modified T7 DNA polymerase. Protein Engineering. 4: 579-84. PMID 1891465 DOI: 10.1093/protein/4.5.579  0.334
1991 Baldwin JE, Blackburn JM, Sutherland JD, Wright MC. High-level soluble expression of isopenicillin N synthase isozymes in E. coli Tetrahedron. 47: 5991-6002. DOI: 10.1016/S0040-4020(01)86491-7  0.602
1990 Baldwin JE, Blackburn JM, Schofield CJ, Sutherland JD. High level expression in Escherichia coli of a fungal gene under the control of strong promoters. Fems Microbiology Letters. 56: 45-51. PMID 2185127 DOI: 10.1016/0378-1097(90)90122-7  0.323
1990 Whiteman PA, Abraham EP, Baldwin JE, Fleming MD, Schofield CJ, Sutherland JD, Willis AC. Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans. Febs Letters. 262: 342-4. PMID 2110531 DOI: 10.1016/0014-5793(90)80224-7  0.483
1988 Baldwin JE, Adlington RM, Crouch NP, Coates JB, Keeping JW, Schofield CJ, Shuttleworth WA, Sutherland JD. Substrate specificity of cloned deacetoxycephalosporin C/deacetylcephalosporin C synthetase. The Journal of Antibiotics. 41: 1694-5. PMID 3198501 DOI: 10.7164/Antibiotics.41.1694  0.567
1987 Baldwin JE, Killin SJ, Pratt AJ, Sutherland JD, Turner NJ, Crabbe MJ, Abraham EP, Willis AC. Purification and characterization of cloned isopenicillin N synthetase. The Journal of Antibiotics. 40: 652-9. PMID 3301770 DOI: 10.7164/Antibiotics.40.652  0.318
Low-probability matches (unlikely to be authored by this person)
2020 Ritson DJ, Mojzsis SJ, Sutherland JD. Supply of phosphate to early Earth by photogeochemistry after meteoritic weathering. Nature Geoscience. 13: 344-348. PMID 32395178 DOI: 10.1038/S41561-020-0556-7  0.3
2010 Bokhove M, Yoshida H, Hensgens CM, van der Laan JM, Sutherland JD, Dijkstra BW. Structures of an isopenicillin N converting Ntn-hydrolase reveal different catalytic roles for the active site residues of precursor and mature enzyme. Structure (London, England : 1993). 18: 301-8. PMID 20223213 DOI: 10.1016/J.Str.2010.01.005  0.298
2017 Ferus M, Kubelík P, Knížek A, Pastorek A, Sutherland J, Civiš S. High Energy Radical Chemistry Formation of HCN-rich Atmospheres on early Earth. Scientific Reports. 7: 6275. PMID 28740207 DOI: 10.1038/S41598-017-06489-1  0.297
1998 Rowe CJ, Shorrock CP, Claridge TD, Sutherland JD. Analysis of the conversion of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate by active-site mutants of Aspergillus nidulans isopenicillin N synthase. Chemistry & Biology. 5: 229-39. PMID 9545433 DOI: 10.1016/S1074-5521(98)90636-6  0.296
1993 Sutherland JD, Wilson EJ, Wright MC. Directed evolution of novel biosynthetic pathways: growth of an escherichia coli proline auxotroph on Δ1-pyrroline-2-carboxylic acid Bioorganic and Medicinal Chemistry Letters. 3: 1185-1188. DOI: 10.1016/S0960-894X(00)80311-X  0.292
2018 Ranjan S, Todd ZR, Sutherland JD, Sasselov DD. Sulfidic Anion Concentrations on Early Earth for Surficial Origins-of-Life Chemistry. Astrobiology. PMID 29627997 DOI: 10.1089/Ast.2017.1770  0.292
1993 Lewis ML, Martin SL, Rowe CJ, Sutherland JD, Wilson EJ, Wright MC. Reduction of Δ1-pyrroline-2-carboxylic acid to proline in escherichia coli: lack of involvement of glutamate dehydrogenase and Δ1-pyrroline-5-carboxylate reductase Bioorganic and Medicinal Chemistry Letters. 3: 1197-1202. DOI: 10.1016/S0960-894X(00)80314-5  0.29
2015 Sutherland JD. The Origin of Life-Out of the Blue. Angewandte Chemie (International Ed. in English). PMID 26510485 DOI: 10.1002/Anie.201506585  0.289
2018 Xu J, Ritson DJ, Ranjan S, Todd ZR, Sasselov DD, Sutherland JD. Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide. Chemical Communications (Cambridge, England). PMID 29761807 DOI: 10.1039/C8Cc01499J  0.288
1998 Sutherland JD, Cook SD. Synthesis and solution structures of aminoacyl compounds of potential prebiotic significance Tetrahedron Letters. 39: 3299-3302. DOI: 10.1016/S0040-4039(98)00475-4  0.285
2014 Albertsen AN, Duffy CD, Sutherland JD, Monnard PA. Self-assembly of phosphate amphiphiles in mixtures of prebiotically plausible surfactants. Astrobiology. 14: 462-72. PMID 24885934 DOI: 10.1089/Ast.2013.1111  0.285
2015 Szabla R, Campos J, Šponer JE, Šponer J, Góra RW, Sutherland JD. Excited-state hydrogen atom abstraction initiates the photochemistry of β-2'-deoxycytidine. Chemical Science (Royal Society of Chemistry : 2010). 6: 2035-2043. PMID 27182431 DOI: 10.1039/C4Sc03761H  0.284
1994 Little AJ, Sutherland JD, Wilson EJ, Wood-Collins DAJ. Directed evolution of novel biosynthetic pathways: Overexpression of leucine aminopeptidase allows an Escherichia coli proline auxotroph to grow faster on prolinamide Bioorganic and Medicinal Chemistry Letters. 4: 2555-2558. DOI: 10.1016/S0960-894X(01)80282-1  0.281
2009 Harris DM, Westerlaken I, Schipper D, van der Krogt ZA, Gombert AK, Sutherland J, Raamsdonk LM, van den Berg MA, Bovenberg RA, Pronk JT, Daran JM. Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor. Metabolic Engineering. 11: 125-37. PMID 19271269 DOI: 10.1016/J.Ymben.2008.12.003  0.279
2020 Liu Z, Wu LF, Xu J, Bonfio C, Russell DA, Sutherland JD. Harnessing chemical energy for the activation and joining of prebiotic building blocks. Nature Chemistry. 12: 1-6. PMID 33093680 DOI: 10.1038/s41557-020-00564-3  0.278
2017 Tsanakopoulou M, Xu J, Bond AD, Sutherland JD. A new and potentially prebiotic α-cytidine derivative. Chemical Communications (Cambridge, England). PMID 28229150 DOI: 10.1039/C7Cc00693D  0.275
2002 Lawrence AJ, Sutherland JD. Synthesis and Properties of Glycolaldehyde Di- and Triphosphate Synlett. 2002: 170-172. DOI: 10.1055/S-2002-19325  0.274
2002 Hensgens CM, Kroezinga EA, van Montfort BA, van der Laan JM, Sutherland JD, Dijkstra BW. Purification, crystallization and preliminary X-ray diffraction of Cys103Ala acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum. Acta Crystallographica. Section D, Biological Crystallography. 58: 716-8. PMID 11914506 DOI: 10.1107/S0907444902003244  0.273
1994 Sutherland JD, Wilson EJ, Wright MC. Directed evolution of novel biosynthetic pathways: Construction of a randomly mutated gene library in an Escherichia coli proline auxotroph and selection for growth on potential proline precursors Bioorganic and Medicinal Chemistry Letters. 4: 2551-2554. DOI: 10.1016/S0960-894X(01)80281-X  0.271
1998 Hall BJ, Sutherland JD. A practical method for the combinatorial synthesis of peptide aldehydes Tetrahedron Letters. 39: 6593-6596. DOI: 10.1016/S0040-4039(98)01374-4  0.271
2020 Sasselov DD, Grotzinger JP, Sutherland JD. The origin of life as a planetary phenomenon. Science Advances. 6: eaax3419. PMID 32076638 DOI: 10.1126/Sciadv.Aax3419  0.268
2008 Powner MW, Sutherland JD. Potentially prebiotic synthesis of pyrimidine beta-D-ribonucleotides by photoanomerization/hydrolysis of alpha-D-cytidine-2'-phosphate. Chembiochem : a European Journal of Chemical Biology. 9: 2386-7. PMID 18798212 DOI: 10.1002/Cbic.200800391  0.265
2021 Naydenova K, Muir KW, Wu LF, Zhang Z, Coscia F, Peet MJ, Castro-Hartmann P, Qian P, Sader K, Dent K, Kimanius D, Sutherland JD, Löwe J, Barford D, Russo CJ. Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526596 DOI: 10.1073/pnas.2021946118  0.264
1996 Cook SD, Sutherland JD. Studies on the reactivity of bisglycoaldehyde phosphodiester in alkaline solution Tetrahedron Letters. 37: 5779-5782. DOI: 10.1016/0040-4039(96)01224-5  0.262
2005 Yoshida H, Hensgens CM, van der Laan JM, Sutherland JD, Hart DJ, Dijkstra BW. An approach to prevent aggregation during the purification and crystallization of wild type acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum. Protein Expression and Purification. 41: 61-7. PMID 15802222 DOI: 10.1016/J.Pep.2005.02.007  0.26
2019 Sutherland J, Ritson D. Do sulfate radicals really enable a non-enzymatic Krebs cycle precursor? Nature Ecology & Evolution. 3: 138. PMID 30697001 DOI: 10.1038/S41559-018-0791-0  0.256
2023 Green NJ, Russell DA, Tanner SH, Sutherland JD. Prebiotic Synthesis of Formylaminonitriles and Derivatives in Formamide. Journal of the American Chemical Society. PMID 37146260 DOI: 10.1021/jacs.2c13306  0.252
2005 Smith JM, Sutherland JD. Aldolisation of bis(glycolaldehyde) phosphate and formaldehyde. Chembiochem : a European Journal of Chemical Biology. 6: 1980-2. PMID 16172991 DOI: 10.1002/Cbic.200500267  0.249
2005 Biron JP, Parkes AL, Pascal R, Sutherland JD. Expeditious, potentially primordial, aminoacylation of nucleotides. Angewandte Chemie (International Ed. in English). 44: 6731-4. PMID 16187390 DOI: 10.1002/Anie.200501591  0.249
1994 Sutherland JD, Weaver GW. Solution structures of bis(glycoaldehyde) phosphodiester and mixed glycoaldehyde-triose phosphodiesters Tetrahedron Letters. 35: 9113-9116. DOI: 10.1016/0040-4039(94)88443-9  0.245
2000 Sutherland JD. Evolutionary optimisation of enzymes. Current Opinion in Chemical Biology. 4: 263-9. PMID 10826970 DOI: 10.1016/S1367-5931(00)00087-9  0.245
2005 Krebs G, Hugonet L, Sutherland JD. Substrate ambiguity and catalytic promiscuity within a bacterial proteome probed by an easy phenotypic screen for aldehydes. Angewandte Chemie (International Ed. in English). 45: 301-5. PMID 16315331 DOI: 10.1002/Anie.200503031  0.241
2020 Liu Z, Wu LF, Bond AD, Sutherland JD. Photoredox chemistry in the synthesis of 2-aminoazoles implicated in prebiotic nucleic acid synthesis. Chemical Communications (Cambridge, England). 56: 13563-13566. PMID 33151212 DOI: 10.1039/d0cc05752e  0.231
2021 Wu LF, Su M, Liu Z, Bjork SJ, Sutherland JD. Interstrand Aminoacyl Transfer in a tRNA Acceptor Stem-Overhang Mimic. Journal of the American Chemical Society. PMID 34283595 DOI: 10.1021/jacs.1c05746  0.228
2023 Ozturk SF, Sasselov DD, Sutherland JD. The central dogma of biological homochirality: How does chiral information propagate in a prebiotic network? The Journal of Chemical Physics. 159. PMID 37551802 DOI: 10.1063/5.0156527  0.224
2020 Bonfio C, Russell DA, Green NJ, Mariani A, Sutherland JD. Activation chemistry drives the emergence of functionalised protocells. Chemical Science. 11: 10688-10697. PMID 34094321 DOI: 10.1039/d0sc04506c  0.224
2000 Connolly AR, Sutherland JD. Catalyst Screening Using an Array of Thermistors. Angewandte Chemie (International Ed. in English). 39: 4268-4271. PMID 29711894 DOI: 10.1002/1521-3773(20001201)39:23<4268::Aid-Anie4268>3.0.Co;2-Z  0.224
2018 Ferus M, Kubelík P, Knížek A, Pastorek A, Sutherland J, Civiš S. Author Correction: High Energy Radical Chemistry Formation of HCN-rich Atmospheres on early Earth. Scientific Reports. 8: 4266. PMID 29511205 DOI: 10.1038/S41598-018-21909-6  0.213
2019 Wu LF, Sutherland JD. Provisioning the origin and early evolution of life. Emerging Topics in Life Sciences. 3: 459-468. PMID 32002470 DOI: 10.1042/ETLS20190011  0.207
2022 Ritson DJ, Poplawski MW, Bond AD, Sutherland JD. Azoles as Auxiliaries and Intermediates in Prebiotic Nucleoside Synthesis. Journal of the American Chemical Society. 144: 19447-19455. PMID 36251009 DOI: 10.1021/jacs.2c07774  0.207
2016 Sutherland JD. Der Ursprung des Lebens: Blausäure Angewandte Chemie. 128: 108-126. DOI: 10.1002/Ange.201506585  0.193
2023 Ritson DJ, Sutherland JD. Thiophosphate photochemistry enables prebiotic access to sugars and terpenoid precursors. Nature Chemistry. PMID 37443293 DOI: 10.1038/s41557-023-01251-9  0.19
2006 Saewan N, Sutherland JD, Chantrapromma K. Antimalarial tetranortriterpenoids from the seeds of Lansium domesticum Corr. Phytochemistry. 67: 2288-93. PMID 16930641 DOI: 10.1016/J.Phytochem.2006.07.005  0.189
2021 Green NJ, Xu J, Sutherland JD. Illuminating Life's Origins: UV Photochemistry in Abiotic Synthesis of Biomolecules. Journal of the American Chemical Society. PMID 33880920 DOI: 10.1021/jacs.1c01839  0.186
2007 Sutherland JD. Die Suche nach einem genetischen Ursystem: jenseits RNA‐verwandter Strukturen Angewandte Chemie. 119: 2406-2408. DOI: 10.1002/Ange.200604374  0.181
2023 Ozturk SF, Liu Z, Sutherland JD, Sasselov DD. Origin of biological homochirality by crystallization of an RNA precursor on a magnetic surface. Science Advances. 9: eadg8274. PMID 37285423 DOI: 10.1126/sciadv.adg8274  0.18
2010 Sutherland J. Accidents will happen Nature Chemistry. 2: 603-603. DOI: 10.1038/Nchem.753  0.169
1982 Sutherland JD, Macdonald IA. The metabolism of primary, 7-oxo, and 7 beta-hydroxy bile acids by Clostridium absonum. Journal of Lipid Research. 23: 726-32. PMID 7119570  0.165
2020 Wu LF, Liu Z, Sutherland JD. pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water. Chemical Communications (Cambridge, England). PMID 33242043 DOI: 10.1039/d0cc06042a  0.163
1982 Sutherland JD, Macdonald IA, Forrest TP. The enzymic and chemical synthesis of ursodeoxycholic and chenodeoxycholic acid from cholic acid. Preparative Biochemistry. 12: 307-21. PMID 6961394 DOI: 10.1080/00327488208065679  0.15
1985 Sutherland JD, Williams CN. Bile acid induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium limosum. Journal of Lipid Research. 26: 344-50. PMID 3857290  0.15
1987 Sutherland JD, Williams CN, Hutchison DM, Holdeman LV. Oxidation of primary bile acids by a 7 alpha-hydroxysteroid dehydrogenase elaborating Clostridium bifermentans soil isolate. Canadian Journal of Microbiology. 33: 663-9. PMID 3480039  0.148
1971 Sutherland JD. Michael Balint (1896-1970). The International Journal of Psycho-Analysis. 52: 331-3. PMID 4944924  0.147
2021 Liu Z, Wu LF, Kufner CL, Sasselov DD, Fischer WW, Sutherland JD. Prebiotic photoredox synthesis from carbon dioxide and sulfite. Nature Chemistry. PMID 34635812 DOI: 10.1038/s41557-021-00789-w  0.145
1983 MacDonald IA, Williams CN, Sutherland JD, MacDonald AC. Estimation of ursodeoxycholic acid in human and bear biles using Clostridium absonum 7 beta-hydroxysteroid dehydrogenase. Analytical Biochemistry. 135: 349-54. PMID 6581749 DOI: 10.1016/0003-2697(83)90695-4  0.141
2020 Bonfio C, Russell DA, Green NJ, Mariani A, Sutherland JD. Activation chemistry drives the emergence of functionalised protocells Chemical Science. 11: 10688-10697. DOI: 10.1039/D0SC04506C  0.14
2011 Carnero E, Sutherland JD, Fortes P. Adenovirus and miRNAs. Biochimica Et Biophysica Acta. 1809: 660-7. PMID 21621026 DOI: 10.1016/j.bbagrm.2011.05.004  0.14
1984 Sutherland JD, Holdeman LV, Williams CN, Macdonald IA. Formation of urso- and ursodeoxy-cholic acids from primary bile acids by a Clostridium limosum soil isolate. Journal of Lipid Research. 25: 1084-9. PMID 6512414  0.134
1983 Macdonald IA, Sutherland JD, Cohen BI, Mosbach EH. Effect of bile acid oxazoline derivatives on microorganisms participating in 7 alpha-hydroxyl epimerization of primary bile acids. Journal of Lipid Research. 24: 1550-9. PMID 6366102  0.123
2011 de Yñigo-Mojado L, Martín-Ruíz I, Sutherland JD. Efficient allele-specific targeting of LRRK2 R1441 mutations mediated by RNAi. Plos One. 6: e21352. PMID 21712955 DOI: 10.1371/journal.pone.0021352  0.122
2013 Pascal R, Pross A, Sutherland JD. Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics. Open Biology. 3: 130156. PMID 24196781 DOI: 10.1098/rsob.130156  0.121
1996 vanderSpek JC, Sutherland J, Sampson E, Murphy JR. Genetic construction and characterization of the diphtheria toxin-related interleukin 15 fusion protein DAB389 sIL-15. Protein Engineering. 8: 1317-21. PMID 8869645 DOI: 10.1093/protein/8.12.1317  0.11
1988 Sutherland JD, Hutchison DM, Williams CN. Lyophilized Clostridium perfringens 3 alpha- and Clostridium bifermentans 7 alpha-hydroxysteroid dehydrogenases: two new stable enzyme preparations for routine bile acid analysis. Biochimica Et Biophysica Acta. 962: 116-21. PMID 2901274 DOI: 10.1016/0005-2760(88)90102-6  0.109
1983 Macdonald IA, Sutherland JD. Further studies on the bile salt induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium absonum. Biochimica Et Biophysica Acta. 750: 397-403. PMID 6574791 DOI: 10.1016/0005-2760(83)90045-0  0.105
2015 Ureña E, Pirone L, Chafino S, Pérez C, Sutherland JD, Lang V, Rodriguez MS, Lopitz-Otsoa F, Blanco FJ, Barrio R, Martín D. Evolution of SUMO function and chain formation in insects. Molecular Biology and Evolution. PMID 26538142 DOI: 10.1093/molbev/msv242  0.102
2011 Sánchez J, Talamillo A, González M, Sánchez-Pulido L, Jiménez S, Pirone L, Sutherland JD, Barrio R. Drosophila Sal and Salr are transcriptional repressors. The Biochemical Journal. 438: 437-45. PMID 21689070 DOI: 10.1042/BJ20110229  0.099
2014 Sutherland JD, Tu NP, Nemcek TA, Searle PA, Hochlowski JE, Djuric SW, Pan JY. An automated synthesis-purification-sample-management platform for the accelerated generation of pharmaceutical candidates. Journal of Laboratory Automation. 19: 176-82. PMID 24352687 DOI: 10.1177/2211068213516325  0.098
2014 Lectez B, Migotti R, Lee SY, Ramirez J, Beraza N, Mansfield B, Sutherland JD, Martinez-Chantar ML, Dittmar G, Mayor U. Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin. Journal of Proteome Research. 13: 3016-26. PMID 24730562 DOI: 10.1021/pr5001913  0.097
2010 Sánchez J, Talamillo A, Lopitz-Otsoa F, Pérez C, Hjerpe R, Sutherland JD, Herboso L, Rodríguez MS, Barrio R. Sumoylation modulates the activity of Spalt-like proteins during wing development in Drosophila. The Journal of Biological Chemistry. 285: 25841-9. PMID 20562097 DOI: 10.1074/jbc.M110.124024  0.093
2011 González M, Martín-Ruíz I, Jiménez S, Pirone L, Barrio R, Sutherland JD. Generation of stable Drosophila cell lines using multicistronic vectors. Scientific Reports. 1: 75. PMID 22355594 DOI: 10.1038/srep00075  0.093
1998 Kozlova T, Pokholkova GV, Tzertzinis G, Sutherland JD, Zhimulev IF, Kafatos FC. Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation. Genetics. 149: 1465-75. PMID 9649534  0.093
2020 Liu Z, Wu LF, Xu J, Bonfio C, Russell DA, Sutherland JD. Publisher Correction: Harnessing chemical energy for the activation and joining of prebiotic building blocks. Nature Chemistry. PMID 33208896 DOI: 10.1038/s41557-020-00591-0  0.087
2015 Navasa N, Martin-Ruiz I, Atondo E, Sutherland JD, Angel Pascual-Itoiz M, Carreras-González A, Izadi H, Tomás-Cortázar J, Ayaz F, Martin-Martin N, Torres IM, Barrio R, Carracedo A, Olivera ER, Rincón M, et al. Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages. Scientific Reports. 5: 14692. PMID 26419808 DOI: 10.1038/Srep14692  0.085
2003 Garvalov BK, Higgins TE, Sutherland JD, Zettl M, Scaplehorn N, Köcher T, Piddini E, Griffiths G, Way M. The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. The Journal of Cell Biology. 161: 33-9. PMID 12695497 DOI: 10.1083/jcb.200211015  0.083
2017 Sutherland JD. Opinion: Studies on the origin of life — the end of the beginning Nature Reviews Chemistry. 1. DOI: 10.1038/s41570-016-0012  0.078
2019 Aspuru-Guzik A, Baik MH, Balasubramanian S, Banerjee R, Bart S, Borduas-Dedekind N, Chang S, Chen P, Corminboeuf C, Coudert FX, Cronin L, Crudden C, Cuk T, Doyle AG, Fan C, ... ... Sutherland J, et al. Charting a course for chemistry. Nature Chemistry. 11: 286-294. PMID 30903035 DOI: 10.1038/S41557-019-0236-7  0.067
1967 Sutherland JD, Gill HS, Phillipson H. Psychodiagnostic appraisal in the light of recent theoretical developments. The British Journal of Medical Psychology. 40: 299-315. PMID 5582758  0.066
2014 Thomas GS, Wann LS, Allam AH, Thompson RC, Michalik DE, Sutherland ML, Sutherland JD, Lombardi GP, Watson L, Cox SL, Valladolid CM, Abd El-Maksoud G, Al-Tohamy Soliman M, Badr I, el-Halim Nur el-Din A, et al. Why did ancient people have atherosclerosis?: from autopsies to computed tomography to potential causes. Global Heart. 9: 229-37. PMID 25667093 DOI: 10.1016/j.gheart.2014.04.002  0.064
2013 Talamillo A, Herboso L, Pirone L, Pérez C, González M, Sánchez J, Mayor U, Lopitz-Otsoa F, Rodriguez MS, Sutherland JD, Barrio R. Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis. Plos Genetics. 9: e1003473. PMID 23637637 DOI: 10.1371/journal.pgen.1003473  0.064
2001 Witke W, Sutherland JD, Sharpe A, Arai M, Kwiatkowski DJ. Profilin I is essential for cell survival and cell division in early mouse development. Proceedings of the National Academy of Sciences of the United States of America. 98: 3832-6. PMID 11274401 DOI: 10.1073/Pnas.051515498  0.063
2015 Herboso L, Oliveira MM, Talamillo A, Pérez C, González M, Martín D, Sutherland JD, Shingleton AW, Mirth CK, Barrio R. Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster. Scientific Reports. 5: 12383. PMID 26198204 DOI: 10.1038/Srep12383  0.06
1991 Cruz YP, Sutherland SA, Sutherland JD. Evaluation of anionic histological dyes as co-injectable cell markers in pre-implantation mouse embryos. The International Journal of Developmental Biology. 35: 57-62. PMID 1868001  0.06
1993 Sutherland JD. The autonomous self. Bulletin of the Menninger Clinic. 57: 3-32; discussion 1-2. PMID 8443615  0.06
2014 Zink A, Wann LS, Thompson RC, Keller A, Maixner F, Allam AH, Finch CE, Frohlich B, Kaplan H, Lombardi GP, Sutherland ML, Sutherland JD, Watson L, Cox SL, Miyamoto MI, et al. Genomic correlates of atherosclerosis in ancient humans. Global Heart. 9: 203-9. PMID 25667090 DOI: 10.1016/J.Gheart.2014.03.2453  0.059
1999 Sutherland JD, Witke W. Molecular genetic approaches to understanding the actin cytoskeleton. Current Opinion in Cell Biology. 11: 142-51. PMID 10047521 DOI: 10.1016/S0955-0674(99)80018-0  0.055
1996 Hsu T, Bagni C, Sutherland JD, Kafatos FC. The transcriptional factor CF2 is a mediator of EGF-R-activated dorsoventral patterning in Drosophila oogenesis. Genes & Development. 10: 1411-21. PMID 8647437 DOI: 10.1101/Gad.10.11.1411  0.054
2014 Gradilla AC, González E, Seijo I, Andrés G, Bischoff M, González-Mendez L, Sánchez V, Callejo A, Ibáñez C, Guerra M, Ortigão-Farias JR, Sutherland JD, González M, Barrio R, Falcón-Pérez JM, et al. Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion. Nature Communications. 5: 5649. PMID 25472772 DOI: 10.1038/Ncomms6649  0.052
2015 Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nature Communications. 6: 7935. PMID 26228240 DOI: 10.1038/Ncomms8935  0.051
1995 Sutherland JD, Kozlova T, Tzertzinis G, Kafatos FC. Drosophila hormone receptor 38: a second partner for Drosophila USP suggests an unexpected role for nuclear receptors of the nerve growth factor-induced protein B type. Proceedings of the National Academy of Sciences of the United States of America. 92: 7966-70. PMID 7644522 DOI: 10.1073/pnas.92.17.7966  0.048
2002 Sutherland JD, Way M. Looking over the edge: a new role for Ena/VASP proteins in lamellipodial dynamics. Developmental Cell. 2: 692-4. PMID 12062081 DOI: 10.1016/S1534-5807(02)00191-0  0.048
2014 Rodriguez MS, Egaña I, Lopitz-Otsoa F, Aillet F, Lopez-Mato MP, Dorronsoro A, Dorronroso A, Lobato-Gil S, Sutherland JD, Barrio R, Trigueros C, Lang V. The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation. Cell Death & Disease. 5: e1399. PMID 25165885 DOI: 10.1038/cddis.2014.366  0.048
1956 SUTHERLAND JD. Freud's life and work; an appreciation of Ernest Jones's biography. The British Journal of Medical Psychology. 29: 77-81. PMID 13329307  0.046
2015 Szabla R, Campos J, Šponer JE, Šponer J, Góra RW, Sutherland JD. Excited-state hydrogen atom abstraction initiates the photochemistry of β-2′-deoxycytidine Chemical Science. 6: 2035-2043. DOI: 10.1039/c4sc03761h  0.042
2014 Clarke EM, Thompson RC, Allam AH, Wann LS, Lombardi GP, Sutherland ML, Sutherland JD, Cox SL, Soliman MA, Abd el-Maksoud G, Badr I, Miyamoto MI, Frohlich B, Nur el-din AH, Stewart AF, et al. Is atherosclerosis fundamental to human aging? Lessons from ancient mummies. Journal of Cardiology. 63: 329-34. PMID 24582386 DOI: 10.1016/j.jjcc.2013.12.012  0.04
1998 Witke W, Podtelejnikov AV, Di Nardo A, Sutherland JD, Gurniak CB, Dotti C, Mann M. In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly. The Embo Journal. 17: 967-76. PMID 9463375 DOI: 10.1093/Emboj/17.4.967  0.039
1993 Klingensmith WC, Sutherland JD. Detection of jeopardized myocardium with Tl-201 myocardial perfusion imaging. Comparison of early and late reinjection protocols. Clinical Nuclear Medicine. 18: 487-90. PMID 8319401  0.034
2014 Thompson RC, Allam AH, Zink A, Wann LS, Lombardi GP, Cox SL, Frohlich B, Sutherland ML, Sutherland JD, Frohlich TC, King SI, Miyamoto MI, Monge JM, Valladolid CM, El-Halim Nur El-Din A, et al. Computed tomographic evidence of atherosclerosis in the mummified remains of humans from around the world. Global Heart. 9: 187-96. PMID 25667088 DOI: 10.1016/j.gheart.2014.03.2455  0.033
1965 Sutherland JD. Recent advances in the understanding of small groups, their disorders and treatment. Psychotherapy and Psychosomatics. 13: 110-25. PMID 5834601  0.029
2015 Fritsch KO, Hamoud H, Allam AH, Grossmann A, Nur El-Din AH, Abdel-Maksoud G, Soliman MA, Badr I, Sutherland JD, Sutherland ML, Akl M, Finch CE, Thomas GS, Wann LS, Thompson RC. The orthopedic diseases of ancient Egypt. Anatomical Record (Hoboken, N.J. : 2007). 298: 1036-46. PMID 25998638 DOI: 10.1002/ar.23136  0.027
2013 Thompson RC, Allam AH, Lombardi GP, Wann LS, Sutherland ML, Sutherland JD, Soliman MA, Frohlich B, Mininberg DT, Monge JM, Vallodolid CM, Cox SL, Abd el-Maksoud G, Badr I, Miyamoto MI, et al. Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations. Lancet. 381: 1211-22. PMID 23489753 DOI: 10.1016/S0140-6736(13)60598-X  0.026
2022 Tsao H, Macdonald R, Dwyer D, Harper T, Rutz D, Sutherland J. Prolonged length of stay is associated with reduced hand hygiene compliance in the emergency department: A single centre retrospective study. Emergency Medicine Australasia : Ema. PMID 36184077 DOI: 10.1111/1742-6723.14097  0.024
1983 Sutherland JD. The self and object relations. A challenge to psychoanalysis. Bulletin of the Menninger Clinic. 47: 525-48. PMID 6652314  0.024
1963 SUTHERLAND JD. Object-relations theory and the conceptual model of psychoanalysis. The British Journal of Medical Psychology. 36: 109-24. PMID 13979395  0.024
1986 Germer S, Campbell IW, Smith AW, Sutherland JD, Jones IG. Do diabetics remember all they have been taught? A survey of knowledge of insulin-dependent diabetics. Diabetic Medicine : a Journal of the British Diabetic Association. 3: 343-5. PMID 2949924  0.023
1965 SUTHERLAND JD. W.R.D. FAIRBAIRN, 1889-1964. The International Journal of Psycho-Analysis. 46: 245-7. PMID 14341702  0.022
1953 SUTHERLAND JD. In memoriam William Brown. The British Journal of Medical Psychology. 26: 1. PMID 13042011  0.022
1971 Bondurant JV, Fisher MW, Sutherland JD. Gandhi; a psychoanalytic view. [Essay review of Erik H. Erikson, Gandhi's truth]. The American Historical Review. 76: 1104-15. PMID 11615442  0.021
2005 Dasch J, D'Arcy J, Gundrum A, Sutherland J, Johnson J, Carlson D. Characterization of fine particles from machining in automotive plants. Journal of Occupational and Environmental Hygiene. 2: 609-625. PMID 16282165 DOI: 10.1080/15459620500377659  0.021
1964 SUTHERLAND JD, GILL HS. THE SIGNIFICANCE OF THE ONE-WAY VISION SCREEN IN ANALYTIC GROUP PSYCHOTHERAPY. The British Journal of Medical Psychology. 37: 185-202. PMID 14192930  0.02
2015 Tipton SC, Sutherland J, Schwarzkopf R. Using the Anatomical Axis as an Alternative to the Mechanical Axis to Assess Knee Alignment. Orthopedics. 38: e1115-20. PMID 26652333 DOI: 10.3928/01477447-20151123-01  0.02
2010 Sutherland J, Banerji N, Morphew J, Johnson E, Dunn D. Postoperative incidence of incarcerated hiatal hernia and its prevention after robotic transhiatal esophagectomy. Surgical Endoscopy. 25: 1526-30. PMID 20976482 DOI: 10.1007/s00464-010-1429-8  0.019
1949 SUTHERLAND JD. Mental health and group relations at work. Health Education Journal. 7: 35-8. PMID 18123769  0.018
2013 Abdelfattah A, Allam AH, Wann S, Thompson RC, Abdel-Maksoud G, Badr I, Amer HA, el-Din Ael-H, Finch CE, Miyamoto MI, Sutherland L, Sutherland JD, Thomas GS. Atherosclerotic cardiovascular disease in Egyptian women: 1570 BCE-2011 CE. International Journal of Cardiology. 167: 570-4. PMID 22357423 DOI: 10.1016/j.ijcard.2012.01.082  0.018
2011 Allam AH, Thompson RC, Wann LS, Miyamoto MI, Nur El-Din Ael-H, El-Maksoud GA, Al-Tohamy Soliman M, Badr I, El-Rahman Amer HA, Sutherland ML, Sutherland JD, Thomas GS. Atherosclerosis in ancient Egyptian mummies: the Horus study. Jacc. Cardiovascular Imaging. 4: 315-27. PMID 21466986 DOI: 10.1016/j.jcmg.2011.02.002  0.016
2014 Allam AH, Mandour Ali MA, Wann LS, Thompson RC, Sutherland ML, Sutherland JD, Frohlich B, Michalik DE, Zink A, Lombardi GP, Watson L, Cox SL, Finch CE, Miyamoto MI, Sallam SL, et al. Atherosclerosis in ancient and modern Egyptians: the Horus study. Global Heart. 9: 197-202. PMID 25667089 DOI: 10.1016/S0735-1097(14)61614-4  0.016
2003 Sutherland J. EXTRACTS from appendix (A) to the Report of the General Board of Health on the Epidemic Cholera of 1848 & 1849(a). International Journal of Epidemiology. 31: 900-7. PMID 12435757 DOI: 10.1093/ije/31.5.900  0.016
2014 Sutherland ML, Cox SL, Lombardi GP, Watson L, Valladolid CM, Finch CE, Zink A, Frohlich B, Kaplan HS, Michalik DE, Miyamoto MI, Allam AH, Thompson RC, Wann LS, Narula J, ... ... Sutherland JD, et al. Funerary artifacts, social status, and atherosclerosis in ancient peruvian mummy bundles. Global Heart. 9: 219-28. PMID 25667092 DOI: 10.1016/j.gheart.2014.04.004  0.016
2010 Hussain J, Strumpf R, Ghandforoush A, Wheatley G, Sutherland J. Transcatheter closure of recurrent aortic pseudoaneurysm previously treated by Amplatzer occluder device. Journal of Vascular Surgery. 52: 196-8. PMID 20434298 DOI: 10.1016/j.jvs.2010.02.005  0.015
2015 Tipton S, Sutherland J, Schwarzkopf R. Change in Limb Length After Total Knee Arthroplasty. Geriatric Orthopaedic Surgery & Rehabilitation. 6: 197-201. PMID 26328236 DOI: 10.1177/2151458515588187  0.014
2014 Wann LS, Thompson RC, Allam AH, Finch CE, Zink A, Frohlich B, Kaplan H, Lombardi GP, Sutherland ML, Sutherland JD, Watson L, Cox SL, Miyamoto MI, Stewart AF, Narula J, et al. Atherosclerosis: a longue durée approach. Global Heart. 9: 239-44. PMID 25667094 DOI: 10.1016/J.Gheart.2014.02.002  0.012
1980 Sutherland JD. The British object relations theorists: Balint, Winnicott, Fairbairn, Guntrip. Journal of the American Psychoanalytic Association. 28: 829-60. PMID 7009698  0.011
1966 Sutherland JD, DeNardo GL, Brown DW. Lung scans with I-131 labelled macroaggregated human serum albumin (maa). The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine. 98: 416-26. PMID 5925112 DOI: 10.2214/AJR.98.2.416  0.011
2023 Sutherland J. Dr. Sutherland on Undiluted Creasote in Burns. Medical Examiner (Philadelphia, Pa.). 5: 302-303. PMID 38119336  0.01
2013 Martin-Martin N, Sutherland JD, Carracedo A. PML: Not all about Tumor Suppression. Frontiers in Oncology. 3: 200. PMID 23936764 DOI: 10.3389/fonc.2013.00200  0.01
2008 Budoff MJ, Dowe D, Jollis JG, Gitter M, Sutherland J, Halamert E, Scherer M, Bellinger R, Martin A, Benton R, Delago A, Min JK. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. Journal of the American College of Cardiology. 52: 1724-32. PMID 19007693 DOI: 10.1016/j.jacc.2008.07.031  0.01
2007 Wheatley GH, Opie SR, Maas D, Sutherland J, Diethrich EB. Atrial septal occluder device surveillance using 64 multi-slice computed tomography. Journal of Cardiac Surgery. 22: 537; discussion 538. PMID 18039227 DOI: 10.1111/J.1540-8191.2007.00466.X  0.01
2007 Wheatley GH, Opie SR, Maas D, Sutherland J, Diethrich EB. Detection of unsuspected mitral valve prolapse using 64 multi-slice computed tomography. The Annals of Thoracic Surgery. 83: 1555. PMID 17383389 DOI: 10.1016/J.Athoracsur.2006.03.031  0.01
2000 Klaus AJ, Klingensmith WC, Parker SH, Stavros AT, Sutherland JD, Aldrete KD. Comparative value of 99mTc-sestamibi scintimammography and sonography in the diagnostic workup of breast masses. Ajr. American Journal of Roentgenology. 174: 1779-83. PMID 10845522 DOI: 10.2214/ajr.174.6.1741779  0.01
1996 Klingensmith WC, Lammertse DP, Briggs DE, Smith WI, Roberts JF, Froelich JW, Sutherland JD. Technetium-99m-MAG3 renal studies in spinal cord injury patients: normal range, reproducibility, and change as a function of duration and level of injury. Spinal Cord. 34: 338-45. PMID 8963987  0.01
1983 Campbell IW, Smith AW, Boyd SG, Duncan CD, Germer S, Sutherland JD, Golda BP, Jones IG. The clinical value of assessing glycosylated haemoglobin (HbA1) in a District General Hospital Diabetic Clinic. Health Bulletin. 41: 95-9. PMID 6341314  0.01
1968 Sutherland JD. [The consulting psychotherapist in the National Health Service: his rôle and training]. Revue De MéDecine Psychosomatique Et De Psychologie MéDicale. 10: 393-405. PMID 5756617  0.01
1968 Sutherland JD. The consultant psychotherapist in the National Health Service: his role and training. The British Journal of Psychiatry : the Journal of Mental Science. 114: 509-15. PMID 5656271  0.01
1966 Sutherland JD. The psychotherapeutic clinic and community psychiatry. Bulletin of the Menninger Clinic. 30: 338-50. PMID 5978710  0.01
1966 Sutherland JD. Industry and 'stress disorder'. Journal of Psychosomatic Research. 10: 71-2. PMID 5938753  0.01
1952 SUTHERLAND JD. Notes on psychoanalytic group therapy. I. Therapy and training. Psychiatry. 15: 111-7. PMID 14930131  0.01
1952 SUTHERLAND JD. Psychological medicine and the national health service: the need for an integrated approach to research. The British Journal of Medical Psychology. 25: 71-85. PMID 12987587  0.01
1941 Sutherland JD. Survey of One Hundred Cases of War Neuroses. British Medical Journal. 2: 365-70. PMID 20783855  0.01
1939 Davidson S, Sutherland JD. Epanutin in Mental Hospital Patients. British Medical Journal. 2: 720-1. PMID 20782685  0.01
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