Alexander D. Johnson - Publications

Affiliations: 
Microbiology & Immunology University of California, San Francisco, San Francisco, CA 
Area:
Molecular Biology of Transcription Circuit Evolution, Candida albicans pathogenesis
Website:
http://bms.ucsf.edu/directory/faculty/alexander-sandy-johnson-phd

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Takagi J, Singh-Babak SD, Lohse MB, Dalal CK, Johnson AD. Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in mouse models of infection. Plos One. 14: e0218037. PMID 31170229 DOI: 10.1371/journal.pone.0218037  1
2019 Mancera E, Frazer C, Porman AM, Ruiz-Castro S, Johnson AD, Bennett RJ. Genetic Modification of Closely Related Species. Frontiers in Microbiology. 10: 357. PMID 30941104 DOI: 10.3389/fmicb.2019.00357  1
2018 Sorrells TR, Johnson AN, Howard CJ, Britton CS, Fowler KR, Feigerle JT, Weil PA, Johnson AD. Intrinsic cooperativity potentiates parallel cis-regulatory evolution. Elife. 7. PMID 30198843 DOI: 10.7554/eLife.37563  0.76
2018 Germann A, Shin D, Kuhrau C, Johnson A, Evers AS, Akk G. High constitutive activity accounts for the combination of enhanced direct activation and reduced potentiation in mutated GABAA receptors. Molecular Pharmacology. PMID 29439087 DOI: 10.1124/mol.117.111435  0.52
2017 Shin DJ, Germann AL, Johnson AD, Forman SA, Steinbach JH, Akk G. Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors. Molecular Pharmacology. PMID 29192122 DOI: 10.1124/mol.117.110403  0.52
2017 Lohse MB, Gulati M, Johnson AD, Nobile CJ. Development and regulation of single- and multi-species Candida albicans biofilms. Nature Reviews. Microbiology. PMID 29062072 DOI: 10.1038/nrmicro.2017.107  1
2017 Dalal CK, Johnson AD. How transcription circuits explore alternative architectures while maintaining overall circuit output. Genes & Development. 31: 1397-1405. PMID 28860157 DOI: 10.1101/gad.303362.117  0.64
2017 Craik VB, Johnson AD, Lohse MB. Sensitivity of White and Opaque Candida albicans to Antifungal Drugs. Antimicrobial Agents and Chemotherapy. PMID 28507115 DOI: 10.1128/AAC.00166-17  1
2017 Nocedal I, Mancera E, Johnson AD. Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator. Elife. 6. PMID 28327289 DOI: 10.7554/eLife.23250  0.64
2017 Lohse MB, Gulati M, Arevalo AV, Fishburn A, Johnson AD, Nobile CJ. Assessment and optimizations of Candida albicans in vitro biofilm assays. Antimicrobial Agents and Chemotherapy. PMID 28289028 DOI: 10.1128/AAC.02749-16  1
2016 Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ. Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells. Mbio. 7. PMID 27879329 DOI: 10.1128/mBio.01269-16  1
2016 Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ. Global Identification of Biofilm-Specific Proteolysis in Candida albicans. Mbio. 7. PMID 27624133 DOI: 10.1128/mBio.01514-16  1
2016 Dalal CK, Zuleta IA, Mitchell KF, Andes DR, El-Samad H, Johnson AD. Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression. Elife. 5. PMID 27614020 DOI: 10.7554/eLife.18981  1
2016 Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD. Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch. Genetics. PMID 27280690 DOI: 10.1534/genetics.116.190645  1
2016 Choi SH, Ruggiero D, Sorice R, Song C, Nutile T, Vernon Smith A, Concas MP, Traglia M, Barbieri C, Ndiaye NC, Stathopoulou MG, Lagou V, Maestrale GB, Sala C, Debette S, ... ... Johnson AD, et al. Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. Plos Genetics. 12: e1005874. PMID 26910538 DOI: 10.1371/journal.pgen.1005874  0.92
2016 Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, ... ... Johnson AD, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications. 7: 10023. PMID 26831199 DOI: 10.1038/ncomms10023  0.92
2016 Hernday AD, Lohse MB, Nobile CJ, Noiman L, Laksana CN, Johnson AD. Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch. Mbio. 7. PMID 26814177 DOI: 10.1128/mBio.01565-15  1
2016 Lohse MB, Johnson AD. Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching. G3 (Bethesda, Md.). PMID 26772749 DOI: 10.1534/g3.115.024885  1
2015 Nocedal I, Johnson AD. How Transcription Networks Evolve and Produce Biological Novelty. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26657905 DOI: 10.1101/sqb.2015.80.027557  1
2015 Eicher JD, Xue L, Ben-Shlomo Y, Beswick AD, Johnson AD. Replication and hematological characterization of human platelet reactivity genetic associations in men from the Caerphilly Prospective Study (CaPS). Journal of Thrombosis and Thrombolysis. PMID 26519038 DOI: 10.1007/s11239-015-1290-7  0.92
2015 Nobile CJ, Johnson AD. Candida albicans Biofilms and Human Disease. Annual Review of Microbiology. 69: 71-92. PMID 26488273 DOI: 10.1146/annurev-micro-091014-104330  1
2015 Liu X, White S, Peng B, Johnson AD, Brody JA, Li AH, Huang Z, Carroll A, Wei P, Gibbs R, Klein RJ, Boerwinkle E. WGSA: an annotation pipeline for human genome sequencing studies. Journal of Medical Genetics. PMID 26395054 DOI: 10.1136/jmedgenet-2015-103423  0.92
2015 Eicher JD, Wakabayashi Y, Vitseva O, Esa N, Yang Y, Zhu J, Freedman JE, McManus DD, Johnson AD. Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction. Platelets. 1-10. PMID 26367242 DOI: 10.3109/09537104.2015.1083543  0.92
2015 Du H, Guan G, Li X, Gulati M, Tao L, Cao C, Johnson AD, Nobile CJ, Huang G. N-Acetylglucosamine-Induced Cell Death in Candida albicans and Its Implications for Adaptive Mechanisms of Nutrient Sensing in Yeasts. Mbio. 6. PMID 26350972 DOI: 10.1128/mBio.01376-15  1
2015 Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, et al. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26293461 DOI: 10.1161/ATVBAHA.115.306108  0.92
2015 Sorrells TR, Booth LN, Tuch BB, Johnson AD. Intersecting transcription networks constrain gene regulatory evolution. Nature. 523: 361-5. PMID 26153861 DOI: 10.1038/nature14613  1
2015 Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, O'Donnell CJ, et al. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Molecular Systems Biology. 11: 799. PMID 26043448  0.92
2015 Sorrells TR, Johnson AD. Making sense of transcription networks. Cell. 161: 714-23. PMID 25957680 DOI: 10.1016/j.cell.2015.04.014  1
2015 O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ. Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 7478-83. PMID 25944934 DOI: 10.1073/pnas.1507082112  1
2015 Rodriguez S, Gaunt TR, Guo Y, Zheng J, Barnes MR, Tang W, Danish F, Johnson A, Castillo BA, Li YR, Hakonarson H, Buxbaum SG, Palmer T, Tsai MY, Lange LA, et al. Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array. European Journal of Human Genetics : Ejhg. PMID 25920552 DOI: 10.1038/ejhg.2015.63  0.92
2015 Yu F, Lu J, Liu X, Gazave E, Chang D, Raj S, Hunter-Zinck H, Blekhman R, Arbiza L, Van Hout C, Morrison A, Johnson AD, Bis J, Cupples LA, Psaty BM, et al. Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions. Plos One. 10: e0121644. PMID 25807536 DOI: 10.1371/journal.pone.0121644  0.92
2015 Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito JM, Yao C, Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, et al. Genome-wide identification of microRNA expression quantitative trait loci. Nature Communications. 6: 6601. PMID 25791433 DOI: 10.1038/ncomms7601  0.92
2015 Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, et al. A meta-analysis of gene expression signatures of blood pressure and hypertension. Plos Genetics. 11: e1005035. PMID 25785607 DOI: 10.1371/journal.pgen.1005035  0.92
2015 Fox EP, Bui CK, Nett JE, Hartooni N, Mui MC, Andes DR, Nobile CJ, Johnson AD. An expanded regulatory network temporally controls Candida albicans biofilm formation. Molecular Microbiology. 96: 1226-39. PMID 25784162 DOI: 10.1111/mmi.13002  1
2015 Sloan A, Gona P, Johnson AD. Cardiovascular correlates of platelet count and volume in the Framingham Heart Study. Annals of Epidemiology. 25: 492-8. PMID 25771288 DOI: 10.1016/j.annepidem.2015.01.010  0.92
2015 Mancera E, Porman AM, Cuomo CA, Bennett RJ, Johnson AD. Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis. G3 (Bethesda, Md.). 5: 849-56. PMID 25758825 DOI: 10.1534/g3.115.017566  1
2015 Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab HA, Min J, Walter K, Memari Y, Huang J, Barnes MR, Beilby JP, Charoen P, ... ... Johnson AD, et al. Whole-genome sequence-based analysis of thyroid function. Nature Communications. 6: 5681. PMID 25743335 DOI: 10.1038/ncomms6681  0.92
2015 Zhang X, Joehanes R, Chen BH, Huan T, Ying S, Munson PJ, Johnson AD, Levy D, O'Donnell CJ. Identification of common genetic variants controlling transcript isoform variation in human whole blood. Nature Genetics. 47: 345-52. PMID 25685889 DOI: 10.1038/ng.3220  0.92
2015 Huan T, Rong J, Tanriverdi K, Meng Q, Bhattacharya A, McManus DD, Joehanes R, Assimes TL, McPherson R, Samani NJ, Erdmann J, Schunkert H, Courchesne P, Munson PJ, Johnson AD, et al. Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1011-21. PMID 25657313 DOI: 10.1161/ATVBAHA.114.305176  0.92
2015 Amendola LM, Dorschner MO, Robertson PD, Salama JS, Hart R, Shirts BH, Murray ML, Tokita MJ, Gallego CJ, Kim DS, Bennett JT, Crosslin DR, Ranchalis J, Jones KL, Rosenthal EA, ... ... Johnson AD, et al. Actionable exomic incidental findings in 6503 participants: challenges of variant classification. Genome Research. 25: 305-15. PMID 25637381 DOI: 10.1101/gr.183483.114  0.92
2015 Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. A systematic heritability analysis of the human whole blood transcriptome. Human Genetics. 134: 343-58. PMID 25585846 DOI: 10.1007/s00439-014-1524-3  0.92
2015 Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, ... ... Johnson AD, et al. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 518: 102-6. PMID 25487149 DOI: 10.1038/nature13917  0.92
2015 Eicher JD, Landowski C, Stackhouse B, Sloan A, Chen W, Jensen N, Lien JP, Leslie R, Johnson AD. GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes. Nucleic Acids Research. 43: D799-804. PMID 25428361 DOI: 10.1093/nar/gku1202  0.92
2015 Debette S, Kamatani Y, Metso TM, Kloss M, Chauhan G, Engelter ST, Pezzini A, Thijs V, Markus HS, Dichgans M, Wolf C, Dittrich R, Touzé E, Southerland AM, Samson Y, ... ... Johnson AD, et al. Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection. Nature Genetics. 47: 78-83. PMID 25420145 DOI: 10.1038/ng.3154  0.92
2015 Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, O'Donnell CJ, et al. Integrative network analysis reveals molecular mechanisms of blood pressure regulation Molecular Systems Biology. 11: 1-15. DOI: 10.15252/msb.20145399  0.92
2015 Johnson A, Waye L, Moore S, Chong S. Exploring and enforcing security guarantees via program dependence graphs Proceedings of the Acm Sigplan Conference On Programming Language Design and Implementation (Pldi). 2015: 291-302. DOI: 10.1145/2737924.2737957  0.92
2015 O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ. Correction: Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome (Proceedings of the National Academy of Sciences United State of America (2015) 112, (7478-7483) DOI: 10.1073/pnas.1507082112) Proceedings of the National Academy of Sciences of the United States of America. 112: E3152. DOI: 10.1073/pnas.1509071112  1
2014 Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimäki T, ... ... Johnson AD, et al. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular Psychiatry. PMID 25469926 DOI: 10.1038/mp.2014.133  0.92
2014 Kavanaugh NL, Zhang AQ, Nobile CJ, Johnson AD, Ribbeck K. Mucins suppress virulence traits of Candida albicans. Mbio. 5: e01911. PMID 25389175 DOI: 10.1128/mBio.01911-14  1
2014 Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, ... ... Johnson AD, et al. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nature Communications. 5: 5068. PMID 25350695 DOI: 10.1038/ncomms6068  0.92
2014 Howard CJ, Hanson-Smith V, Kennedy KJ, Miller CJ, Lou HJ, Johnson AD, Turk BE, Holt LJ. Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity. Elife. 3. PMID 25310241 DOI: 10.7554/eLife.04126  1
2014 Fox EP, Cowley ES, Nobile CJ, Hartooni N, Newman DK, Johnson AD. Anaerobic bacteria grow within Candida albicans biofilms and induce biofilm formation in suspension cultures. Current Biology : Cb. 24: 2411-6. PMID 25308076 DOI: 10.1016/j.cub.2014.08.057  1
2014 Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ. Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion. The Journal of Clinical Investigation. 124: 4503-16. PMID 25244095 DOI: 10.1172/JCI71245  0.92
2014 Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, ... ... Johnson AD, et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 514: 92-7. PMID 25231870 DOI: 10.1038/nature13545  0.92
2014 Rietveld CA, Esko T, Davies G, Pers TH, Turley P, Benyamin B, Chabris CF, Emilsson V, Johnson AD, Lee JJ, de Leeuw C, Marioni RE, Medland SE, Miller MB, Rostapshova O, et al. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proceedings of the National Academy of Sciences of the United States of America. 111: 13790-4. PMID 25201988 DOI: 10.1073/pnas.1404623111  0.92
2014 Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, et al. Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics. 23: 6944-60. PMID 25096241 DOI: 10.1093/hmg/ddu401  0.92
2014 Narayanan M, Huynh JL, Wang K, Yang X, Yoo S, McElwee J, Zhang B, Zhang C, Lamb JR, Xie T, Suver C, Molony C, Melquist S, Johnson AD, Fan G, et al. Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases. Molecular Systems Biology. 10: 743. PMID 25080494 DOI: 10.15252/msb.20145304  0.92
2014 Lohse MB, Rosenberg OS, Cox JS, Stroud RM, Finer-Moore JS, Johnson AD. Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi. Proceedings of the National Academy of Sciences of the United States of America. 111: 10404-10. PMID 24994900 DOI: 10.1073/pnas.1410110111  1
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/j.ymgme.2014.04.007  0.92
2014 Sen SK, Boelte KC, Barb JJ, Joehanes R, Zhao X, Cheng Q, Adams L, Teer JK, Accame DS, Chowdhury S, Singh LN, Kavousi M, Peyser PA, ... ... Johnson AD, et al. Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification. American Journal of Human Genetics. 95: 66-76. PMID 24975946 DOI: 10.1016/j.ajhg.2014.06.003  0.92
2014 Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, ... ... Johnson AD, et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. American Journal of Human Genetics. 95: 49-65. PMID 24975945 DOI: 10.1016/j.ajhg.2014.06.002  0.92
2014 Zhang X, Gierman HJ, Levy D, Plump A, Dobrin R, Goring HH, Curran JE, Johnson MP, Blangero J, Kim SK, O'Donnell CJ, Emilsson V, Johnson AD. Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs. Bmc Genomics. 15: 532. PMID 24973796 DOI: 10.1186/1471-2164-15-532  0.92
2014 Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, ... ... Johnson AD, et al. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. American Journal of Human Genetics. 95: 24-38. PMID 24954895 DOI: 10.1016/j.ajhg.2014.05.010  0.92
2014 Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/ng.3014  0.92
2014 Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HC, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WH, Liu CT, ... ... Johnson AD, et al. Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 374-82. PMID 24951664 DOI: 10.1161/CIRCGENETICS.113.000169  0.92
2014 Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, Bressler J, Liu X, Davis BC, Johnson AD, O'Donnell CJ, et al. Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 335-43. PMID 24951659 DOI: 10.1161/CIRCGENETICS.113.000350  0.92
2014 Leslie R, O'Donnell CJ, Johnson AD. GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database. Bioinformatics (Oxford, England). 30: i185-94. PMID 24931982 DOI: 10.1093/bioinformatics/btu273  0.92
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Johnson AD, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/journal.pone.0094661  0.92
2014 Nobile CJ, Fox EP, Hartooni N, Mitchell KF, Hnisz D, Andes DR, Kuchler K, Johnson AD. A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans. Mbio. 5: e01201-14. PMID 24917598 DOI: 10.1128/mBio.01201-14  0.8
2014 Pérez JC, Fordyce PM, Lohse MB, Hanson-Smith V, DeRisi JL, Johnson AD. How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes. Genes & Development. 28: 1272-7. PMID 24874988 DOI: 10.1101/gad.242271.114  1
2014 Huang J, Huffman JE, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, ... Johnson AD, et al. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1093-101. PMID 24578379 DOI: 10.1161/ATVBAHA.113.302088  0.92
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/ng.2897  0.92
2014 Perry JR, Hsu YH, Chasman DI, Johnson AD, Elks C, Albrecht E, Andrulis IL, Beesley J, Berenson GS, Bergmann S, Bojesen SE, Bolla MK, Brown J, Buring JE, Campbell H, et al. DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Human Molecular Genetics. 23: 2490-7. PMID 24357391 DOI: 10.1093/hmg/ddt620  0.92
2014 Gordon AS, Tabor HK, Johnson AD, Snively BM, Assimes TL, Auer PL, Ioannidis JP, Peters U, Robinson JG, Sucheston LE, Wang D, Sotoodehnia N, Rotter JI, Psaty BM, Jackson RD, et al. Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset. Human Molecular Genetics. 23: 1957-63. PMID 24282029 DOI: 10.1093/hmg/ddt588  0.92
2014 Yao C, Joehanes R, Johnson AD, Huan T, Esko T, Ying S, Freedman JE, Murabito J, Lunetta KL, Metspalu A, Munson PJ, Levy D. Sex- and age-interacting eQTLs in human complex diseases. Human Molecular Genetics. 23: 1947-56. PMID 24242183 DOI: 10.1093/hmg/ddt582  0.92
2014 Zhang X, Johnson AD, Hendricks AE, Hwang SJ, Tanriverdi K, Ganesh SK, Smith NL, Peyser PA, Freedman JE, O'Donnell CJ. Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. Human Molecular Genetics. 23: 782-95. PMID 24057673 DOI: 10.1093/hmg/ddt461  0.92
2013 Pérez JC, Johnson AD. Regulatory circuits that enable proliferation of the fungus Candida albicans in a mammalian host. Plos Pathogens. 9: e1003780. PMID 24385896 DOI: 10.1371/journal.ppat.1003780  1
2013 Baker CR, Hanson-Smith V, Johnson AD. Following gene duplication, paralog interference constrains transcriptional circuit evolution. Science (New York, N.Y.). 342: 104-8. PMID 24092741 DOI: 10.1126/science.1240810  1
2013 Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, et al. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. The Journal of Clinical Investigation. 123: 4208-18. PMID 23999434 DOI: 10.1172/JCI67119  0.92
2013 Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. American Journal of Human Genetics. 93: 545-54. PMID 23972371 DOI: 10.1016/j.ajhg.2013.07.010  0.92
2013 Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, et al. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 128: 1310-24. PMID 23969696 DOI: 10.1161/CIRCULATIONAHA.113.002251  0.92
2013 Hernday AD, Lohse MB, Fordyce PM, Nobile CJ, DeRisi JL, Johnson AD. Structure of the transcriptional network controlling white-opaque switching in Candida albicans. Molecular Microbiology. 90: 22-35. PMID 23855748 DOI: 10.1111/mmi.12329  1
2013 van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, ... ... Johnson AD, et al. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. The American Journal of Clinical Nutrition. 98: 668-76. PMID 23824729 DOI: 10.3945/ajcn.112.044545  0.92
2013 Morrison AC, Voorman A, Johnson AD, Liu X, Yu J, Li A, Muzny D, Yu F, Rice K, Zhu C, Bis J, Heiss G, O'Donnell CJ, Psaty BM, Cupples LA, et al. Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nature Genetics. 45: 899-901. PMID 23770607 DOI: 10.1038/ng.2671  0.92
2013 Lin CH, Kabrawala S, Fox EP, Nobile CJ, Johnson AD, Bennett RJ. Genetic control of conventional and pheromone-stimulated biofilm formation in Candida albicans. Plos Pathogens. 9: e1003305. PMID 23637598 DOI: 10.1371/journal.ppat.1003305  1
2013 Tanaka T, Ngwa JS, van Rooij FJ, Zillikens MC, Wojczynski MK, Frazier-Wood AC, Houston DK, Kanoni S, Lemaitre RN, Luan J, Mikkilä V, Renstrom F, Sonestedt E, Zhao JH, Chu AY, ... ... Johnson A, et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition. 97: 1395-402. PMID 23636237 DOI: 10.3945/ajcn.112.052183  0.92
2013 Lohse MB, Hernday AD, Fordyce PM, Noiman L, Sorrells TR, Hanson-Smith V, Nobile CJ, DeRisi JL, Johnson AD. Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains. Proceedings of the National Academy of Sciences of the United States of America. 110: 7660-5. PMID 23610392 DOI: 10.1073/pnas.1221734110  1
2013 Xie J, Tao L, Nobile CJ, Tong Y, Guan G, Sun Y, Cao C, Hernday AD, Johnson AD, Zhang L, Bai FY, Huang G. White-opaque switching in natural MTLa/α isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex. Plos Biology. 11: e1001525. PMID 23555196 DOI: 10.1371/journal.pbio.1001525  1
2013 Joehanes R, Ying S, Huan T, Johnson AD, Raghavachari N, Wang R, Liu P, Woodhouse KA, Sen SK, Tanriverdi K, Courchesne P, Freedman JE, O'Donnell CJ, Levy D, Munson PJ. Gene expression signatures of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1418-26. PMID 23539218 DOI: 10.1161/ATVBAHA.112.301169  0.92
2013 Huan T, Zhang B, Wang Z, Joehanes R, Zhu J, Johnson AD, Ying S, Munson PJ, Raghavachari N, Wang R, Liu P, Courchesne P, Hwang SJ, Assimes TL, McPherson R, et al. A systems biology framework identifies molecular underpinnings of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1427-34. PMID 23539213 DOI: 10.1161/ATVBAHA.112.300112  0.92
2013 Pérez JC, Kumamoto CA, Johnson AD. Candida albicans commensalism and pathogenicity are intertwined traits directed by a tightly knit transcriptional regulatory circuit. Plos Biology. 11: e1001510. PMID 23526879 DOI: 10.1371/journal.pbio.1001510  1
2013 Si H, Hernday AD, Hirakawa MP, Johnson AD, Bennett RJ. Candida albicans white and opaque cells undergo distinct programs of filamentous growth. Plos Pathogens. 9: e1003210. PMID 23505370 DOI: 10.1371/journal.ppat.1003210  1
2013 Johnson AD, Hwang SJ, Voorman A, Morrison A, Peloso GM, Hsu YH, Thanassoulis G, Newton-Cheh C, Rogers IS, Hoffmann U, Freedman JE, Fox CS, Psaty BM, Boerwinkle E, Cupples LA, et al. Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study. Circulation. 127: 799-810. PMID 23315372 DOI: 10.1161/CIRCULATIONAHA.112.111559  0.92
2013 Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics. 45: 145-54. PMID 23263486 DOI: 10.1038/ng.2500  0.92
2012 Auer PL, Johnsen JM, Johnson AD, Logsdon BA, Lange LA, Nalls MA, Zhang G, Franceschini N, Fox K, Lange EM, Rich SS, O'Donnell CJ, Jackson RD, Wallace RB, Chen Z, et al. Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. American Journal of Human Genetics. 91: 794-808. PMID 23103231 DOI: 10.1016/j.ajhg.2012.08.031  0.92
2012 Baker CR, Booth LN, Sorrells TR, Johnson AD. Protein modularity, cooperative binding, and hybrid regulatory states underlie transcriptional network diversification. Cell. 151: 80-95. PMID 23021217 DOI: 10.1016/j.cell.2012.08.018  1
2012 Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, et al. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clinical Chemistry. 58: 1582-91. PMID 22997280 DOI: 10.1373/clinchem.2012.190322  0.92
2012 Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, et al. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 120: 4873-81. PMID 22990020 DOI: 10.1182/blood-2012-06-436188  0.92
2012 Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, ... ... Johnson AD, et al. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics. 21: 5329-43. PMID 22962313 DOI: 10.1093/hmg/dds369  0.92
2012 Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. 60: 949-56. PMID 22949535 DOI: 10.1161/HYPERTENSIONAHA.112.196519  0.92
2012 Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, ... ... Johnson AD, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics. 44: 981-90. PMID 22885922 DOI: 10.1038/ng.2383  0.92
2012 Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, ... ... Johnson AD, et al. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. Plos Genetics. 8: e1002805. PMID 22829776 DOI: 10.1371/journal.pgen.1002805  0.92
2012 Tang W, Schwienbacher C, Lopez LM, Ben-Shlomo Y, Oudot-Mellakh T, Johnson AD, Samani NJ, Basu S, Gögele M, Davies G, Lowe GD, Tregouet DA, Tan A, Pankow JS, Tenesa A, et al. Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. American Journal of Human Genetics. 91: 152-62. PMID 22703881 DOI: 10.1016/j.ajhg.2012.05.009  0.92
2012 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, ... ... Johnson AD, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/journal.pgen.1002741  0.92
2012 Fox CS, White CC, Lohman K, Heard-Costa N, Cohen P, Zhang Y, Johnson AD, Emilsson V, Liu CT, Chen YD, Taylor KD, Allison M, Budoff M, Rotter JI, et al. Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. Plos Genetics. 8: e1002705. PMID 22589742 DOI: 10.1371/journal.pgen.1002705  0.92
2012 Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. Plos Genetics. 8: e1002695. PMID 22589738 DOI: 10.1371/journal.pgen.1002695  0.92
2012 Johnson AD. Hemophilia B gene therapy in humans shows promise. Circulation. Cardiovascular Genetics. 5: 269-70. PMID 22511710 DOI: 10.1161/CIRCGENETICS.112.963231  0.92
2012 Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, ... ... Johnson AD, et al. Genome-wide association and functional follow-up reveals new loci for kidney function. Plos Genetics. 8: e1002584. PMID 22479191 DOI: 10.1371/journal.pgen.1002584  0.92
2012 Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga JJ, Kraft P, ... ... Johnson AD, et al. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genetics. 44: 260-8. PMID 22267201 DOI: 10.1038/ng.1051  0.92
2012 Nobile CJ, Fox EP, Nett JE, Sorrells TR, Mitrovich QM, Hernday AD, Tuch BB, Andes DR, Johnson AD. A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell. 148: 126-38. PMID 22265407 DOI: 10.1016/j.cell.2011.10.048  0.8
2012 Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD. A conserved transcriptional regulator governs fungal morphology in widely diverged species. Genetics. 190: 511-21. PMID 22095082 DOI: 10.1534/genetics.111.134080  0.8
2012 Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, ... ... Johnson AD, et al. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circulation. Cardiovascular Genetics. 5: 81-90. PMID 22068335 DOI: 10.1161/CIRCGENETICS.111.959817  0.92
2012 Joehanes R, Johnson AD, Barb JJ, Raghavachari N, Liu P, Woodhouse KA, O'Donnell CJ, Munson PJ, Levy D. Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study. Physiological Genomics. 44: 59-75. PMID 22045913 DOI: 10.1152/physiolgenomics.00130.2011  0.92
2011 O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, ... ... Johnson AD, et al. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 124: 2855-64. PMID 22144573 DOI: 10.1161/CIRCULATIONAHA.110.974899  0.92
2011 Johnson AD, Leslie R, O'Donnell CJ. Temporal trends in results availability from genome-wide association studies. Plos Genetics. 7: e1002269. PMID 21931563 DOI: 10.1371/journal.pgen.1002269  0.92
2011 Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478: 103-9. PMID 21909115 DOI: 10.1038/nature10405  0.92
2011 Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, et al. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics. 43: 1005-11. PMID 21909110 DOI: 10.1038/ng.922  0.92
2011 Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, et al. Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood. 118: 3367-75. PMID 21791418 DOI: 10.1182/blood-2010-11-320788  0.92
2011 Johnson AD. The genetics of common variation affecting platelet development, function and pharmaceutical targeting Journal of Thrombosis and Haemostasis. 9: 246-257. PMID 21781261 DOI: 10.1111/j.1538-7836.2011.04359.x  0.92
2011 Baker CR, Tuch BB, Johnson AD. Extensive DNA-binding specificity divergence of a conserved transcription regulator. Proceedings of the National Academy of Sciences of the United States of America. 108: 7493-8. PMID 21498688 DOI: 10.1073/pnas.1019177108  1
2011 Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC, Launer LJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, Caulfield M, van Duijn CM, et al. Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension. 57: 903-10. PMID 21444836 DOI: 10.1161/HYPERTENSIONAHA.110.158667  0.92
2011 Huang J, Johnson AD, O'Donnell CJ. PRIMe: A method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies Bioinformatics. 27: 1201-1206. PMID 21398673 DOI: 10.1093/bioinformatics/btr116  0.92
2011 Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, ... ... Johnson AD, et al. CUBN is a gene locus for albuminuria. Journal of the American Society of Nephrology : Jasn. 22: 555-70. PMID 21355061 DOI: 10.1681/ASN.2010060598  0.92
2011 Johnson AD, Prakash S. Top advances in functional genomics and translational biology for 2010 Circulation: Cardiovascular Genetics. 4: 94-97. PMID 21325166 DOI: 10.1161/CIRCGENETICS.111.959502  0.92
2011 Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, Johnson AD. Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy. Clinical Pharmacology and Therapeutics. 89: 355-65. PMID 21289622 DOI: 10.1038/clpt.2010.314  0.92
2011 Domire JS, Green JA, Lee KG, Johnson AD, Askwith CC, Mykytyn K. Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins. Cellular and Molecular Life Sciences : Cmls. 68: 2951-60. PMID 21152952 DOI: 10.1007/s00018-010-0603-4  0.92
2011 Ho JE, Levy D, Rose L, Johnson AD, Ridker PM, Chasman DI. Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study. Journal of Hypertension. 29: 62-9. PMID 21045733 DOI: 10.1097/HJH.0b013e3283406927  0.92
2011 Wassel CL, Lange LA, Keating BJ, Taylor KC, Johnson AD, Palmer C, Ho LA, Smith NL, Lange EM, Li Y, Yang Q, Delaney JA, Tang W, Tofler G, Redline S, et al. Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe). Blood. 117: 268-75. PMID 20978265 DOI: 10.1182/blood-2010-06-289546  0.92
2010 Booth LN, Tuch BB, Johnson AD. Intercalation of a new tier of transcription regulation into an ancient circuit. Nature. 468: 959-63. PMID 21164485 DOI: 10.1038/nature09560  1
2010 Mitrovich QM, Tuch BB, De La Vega FM, Guthrie C, Johnson AD. Evolution of yeast noncoding RNAs reveals an alternative mechanism for widespread intron loss Science. 330: 838-841. PMID 21051641 DOI: 10.1126/science.1194554  1
2010 Hernday AD, Noble SM, Mitrovich QM, Johnson AD. Genetics and molecular biology in Candida albicans. Methods in Enzymology. 470: 737-58. PMID 20946834 DOI: 10.1016/S0076-6879(10)70031-8  1
2010 Musunuru K, Post WS, Herzog W, Shen H, O'Connell JR, McArdle PF, Ryan KA, Gibson Q, Cheng YC, Clearfield E, Johnson AD, Tofler G, Yang Q, O'Donnell CJ, Becker DM, et al. Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. Circulation. Cardiovascular Genetics. 3: 445-53. PMID 20858905 DOI: 10.1161/CIRCGENETICS.109.923508  0.92
2010 Li H, Johnson AD. Evolution of transcription networks--lessons from yeasts. Current Biology : Cb. 20: R746-53. PMID 20833319 DOI: 10.1016/j.cub.2010.06.056  1
2010 Tuch BB, Mitrovich QM, Homann OR, Hernday AD, Monighetti CK, De La Vega FM, Johnson AD. The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation. Plos Genetics. 6: e1001070. PMID 20808890 DOI: 10.1371/journal.pgen.1001070  1
2010 Lohse MB, Johnson AD. Temporal anatomy of an epigenetic switch in cell programming: the white-opaque transition of C. albicans. Molecular Microbiology. 78: 331-43. PMID 20735781 DOI: 10.1111/j.1365-2958.2010.07331.x  1
2010 O'Seaghdha CM, Yang Q, Glazer NL, Leak TS, Dehghan A, Smith AV, Kao WH, Lohman K, Hwang SJ, Johnson AD, Hofman A, Uitterlinden AG, Chen YD, Brown EM, et al. Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Human Molecular Genetics. 19: 4296-303. PMID 20705733 DOI: 10.1093/hmg/ddq342  0.92
2010 Lohse MB, Zordan RE, Cain CW, Johnson AD. Distinct class of DNA-binding domains is exemplified by a master regulator of phenotypic switching in Candida albicans. Proceedings of the National Academy of Sciences of the United States of America. 107: 14105-10. PMID 20660774 DOI: 10.1073/pnas.1005911107  1
2010 Freedman JE, Larson MG, Tanriverdi K, O'Donnell CJ, Morin K, Hakanson AS, Vasan RS, Johnson AD, Iafrati MD, Benjamin EJ. Relation of platelet and leukocyte inflammatory transcripts to body mass index in the framingham heart study Circulation. 122: 119-129. PMID 20606121 DOI: 10.1161/CIRCULATIONAHA.109.928192  0.92
2010 Johnson AD, Bhimavarapu A, Benjamin EJ, Fox C, Levy D, Jarvik GP, O'Donnell CJ. CLIA-tested genetic variants on commercial SNP arrays: Potential for incidental findings in genome-wide association studies Genetics in Medicine. 12: 355-363. PMID 20556870 DOI: 10.1097/GIM.0b013e3181e1e2a9  0.92
2010 Noble SM, French S, Kohn LA, Chen V, Johnson AD. Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nature Genetics. 42: 590-8. PMID 20543849 DOI: 10.1038/ng.605  1
2010 Johnson AD, Yanek LR, Chen MH, Faraday N, Larson MG, Tofler G, Lin SJ, Kraja AT, Province MA, Yang Q, Becker DM, O'Donnell CJ, Becker LC. Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Nature Genetics. 42: 608-13. PMID 20526338 DOI: 10.1038/ng.604  0.92
2010 Levy D, Neuhausen SL, Hunt SC, Kimura M, Hwang SJ, Chen W, Bis JC, Fitzpatrick AL, Smith E, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter JI, Herbig U, et al. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proceedings of the National Academy of Sciences of the United States of America. 107: 9293-8. PMID 20421499 DOI: 10.1073/pnas.0911494107  0.92
2010 Homann OR, Johnson AD. MochiView: versatile software for genome browsing and DNA motif analysis. Bmc Biology. 8: 49. PMID 20409324 DOI: 10.1186/1741-7007-8-49  1
2010 Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, ... ... Johnson AD, et al. New loci associated with kidney function and chronic kidney disease. Nature Genetics. 42: 376-84. PMID 20383146 DOI: 10.1038/ng.568  0.92
2010 Johnson AD. An extended IUPAC nomenclature code for polymorphic nucleic acids Bioinformatics. 26: 1386-1389. PMID 20202974 DOI: 10.1093/bioinformatics/btq098  0.92
2009 Homann OR, Dea J, Noble SM, Johnson AD. A phenotypic profile of the Candida albicans regulatory network. Plos Genetics. 5: e1000783. PMID 20041210 DOI: 10.1371/journal.pgen.1000783  1
2009 Lohse MB, Johnson AD. White-opaque switching in Candida albicans. Current Opinion in Microbiology. 12: 650-4. PMID 19853498 DOI: 10.1016/j.mib.2009.09.010  1
2009 Elson SL, Noble SM, Solis NV, Filler SG, Johnson AD. An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth. Plos Genetics. 5: e1000664. PMID 19779551 DOI: 10.1371/journal.pgen.1000664  1
2009 Holt LJ, Tuch BB, Villén J, Johnson AD, Gygi SP, Morgan DO. Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science (New York, N.Y.). 325: 1682-6. PMID 19779198 DOI: 10.1126/science.1172867  1
2009 Nobile CJ, Nett JE, Hernday AD, Homann OR, Deneault JS, Nantel A, Andes DR, Johnson AD, Mitchell AP. Biofilm matrix regulation by Candida albicans Zap1. Plos Biology. 7: e1000133. PMID 19529758 DOI: 10.1371/journal.pbio.1000133  0.8
2009 Stroschein-Stevenson SL, Foley E, O'Farrell PH, Johnson AD. Phagocytosis of Candida albicans by RNAi-treated Drosophila S2 cells. Methods in Molecular Biology (Clifton, N.J.). 470: 347-58. PMID 19089394 DOI: 10.1007/978-1-59745-204-5_24  1
2008 Forche A, Alby K, Schaefer D, Johnson AD, Berman J, Bennett RJ. The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. Plos Biology. 6: e110. PMID 18462019 DOI: 10.1371/journal.pbio.0060110  1
2008 Tuch BB, Li H, Johnson AD. Evolution of eukaryotic transcription circuits. Science (New York, N.Y.). 319: 1797-9. PMID 18369141 DOI: 10.1126/science.1152398  1
2008 Tuch BB, Galgoczy DJ, Hernday AD, Li H, Johnson AD. The evolution of combinatorial gene regulation in fungi. Plos Biology. 6: e38. PMID 18303948 DOI: 10.1371/journal.pbio.0060038  1
2008 Lohse MB, Johnson AD. Differential phagocytosis of white versus opaque Candida albicans by Drosophila and mouse phagocytes. Plos One. 3: e1473. PMID 18213381 DOI: 10.1371/journal.pone.0001473  1
2007 Zordan RE, Miller MG, Galgoczy DJ, Tuch BB, Johnson AD. Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans. Plos Biology. 5: e256. PMID 17880264 DOI: 10.1371/journal.pbio.0050256  1
2007 Noble SM, Johnson AD. Genetics of Candida albicans, a diploid human fungal pathogen. Annual Review of Genetics. 41: 193-211. PMID 17614788 DOI: 10.1146/annurev.genet.41.042007.170146  1
2007 Mitrovich QM, Tuch BB, Guthrie C, Johnson AD. Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans. Genome Research. 17: 492-502. PMID 17351132 DOI: 10.1101/gr.6111907  1
2006 Tsong AE, Tuch BB, Li H, Johnson AD. Evolution of alternative transcriptional circuits with identical logic. Nature. 443: 415-20. PMID 17006507 DOI: 10.1038/nature05099  1
2006 Bennett RJ, Johnson AD. The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans. Molecular Microbiology. 62: 100-19. PMID 16987174 DOI: 10.1111/j.1365-2958.2006.05367.x  1
2006 Zordan RE, Galgoczy DJ, Johnson AD. Epigenetic properties of white-opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 103: 12807-12. PMID 16899543 DOI: 10.1073/pnas.0605138103  1
2006 Stroschein-Stevenson SL, Foley E, O'Farrell PH, Johnson AD. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Plos Biology. 4: e4. PMID 16336044 DOI: 10.1371/journal.pbio.0040004  0.8
2005 Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A, Inglis DO, Uhl MA, Hogues H, Berriman M, Lorenz M, Levitin A, Oberholzer U, Bachewich C, Harcus D, ... ... Johnson AD, et al. A human-curated annotation of the Candida albicans genome. Plos Genetics. 1: 36-57. PMID 16103911 DOI: 10.1371/journal.pgen.0010001  1
2005 Hromatka BS, Noble SM, Johnson AD. Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence. Molecular Biology of the Cell. 16: 4814-26. PMID 16030247 DOI: 10.1091/mbc.E05-05-0435  1
2005 Kadosh D, Johnson AD. Induction of the Candida albicans filamentous growth program by relief of transcriptional repression: a genome-wide analysis. Molecular Biology of the Cell. 16: 2903-12. PMID 15814840 DOI: 10.1091/mbc.E05-01-0073  1
2005 Green SR, Johnson AD. Genome-wide analysis of the functions of a conserved surface on the corepressor Tup1. Molecular Biology of the Cell. 16: 2605-13. PMID 15788561 DOI: 10.1091/mbc.E05-02-0126  1
2005 Noble SM, Johnson AD. Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans. Eukaryotic Cell. 4: 298-309. PMID 15701792 DOI: 10.1128/EC.4.2.298-309.2005  1
2005 Bennett RJ, Miller MG, Chua PR, Maxon ME, Johnson AD. Nuclear fusion occurs during mating in Candida albicans and is dependent on the KAR3 gene. Molecular Microbiology. 55: 1046-59. PMID 15686553 DOI: 10.1111/j.1365-2958.2005.04466.x  1
2004 Galgoczy DJ, Cassidy-Stone A, Llinás M, O'Rourke SM, Herskowitz I, DeRisi JL, Johnson AD. Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 18069-74. PMID 15604142 DOI: 10.1073/pnas.0407611102  1
2004 Green SR, Johnson AD. Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae. Molecular Biology of the Cell. 15: 4191-202. PMID 15240822 DOI: 10.1091/mbc.E04-05-0412  1
2003 Tsong AE, Miller MG, Raisner RM, Johnson AD. Evolution of a combinatorial transcriptional circuit: a case study in yeasts. Cell. 115: 389-99. PMID 14622594 DOI: 10.1016/S0092-8674(03)00885-7  1
2003 Bennett RJ, Uhl MA, Miller MG, Johnson AD. Identification and characterization of a Candida albicans mating pheromone. Molecular and Cellular Biology. 23: 8189-201. PMID 14585977 DOI: 10.1128/MCB.23.22.8189-8201.2003  1
2003 Uhl MA, Biery M, Craig N, Johnson AD. Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans. The Embo Journal. 22: 2668-78. PMID 12773383 DOI: 10.1093/emboj/cdg256  0.72
2003 Bennett RJ, Johnson AD. Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains. The Embo Journal. 22: 2505-15. PMID 12743044 DOI: 10.1093/emboj/cdg235  1
2003 Simic R, Lindstrom DL, Tran HG, Roinick KL, Costa PJ, Johnson AD, Hartzog GA, Arndt KM. Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes. The Embo Journal. 22: 1846-56. PMID 12682017 DOI: 10.1093/emboj/cdg179  1
2002 Inglis DO, Johnson AD. Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans. Molecular and Cellular Biology. 22: 8669-80. PMID 12446785 DOI: 10.1128/MCB.22.24.8669-8680.2002  1
2002 Lockhart SR, Pujol C, Daniels KJ, Miller MG, Johnson AD, Pfaller MA, Soll DR. In Candida albicans, white-opaque switchers are homozygous for mating type. Genetics. 162: 737-45. PMID 12399384  1
2002 Miller MG, Johnson AD. White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating. Cell. 110: 293-302. PMID 12176317 DOI: 10.1016/S0092-8674(02)00837-1  1
2000 Hull CM, Raisner RM, Johnson AD. Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host. Science (New York, N.Y.). 289: 307-10. PMID 10894780 DOI: 10.1126/science.289.5477.307  1
2000 Sprague ER, Redd MJ, Johnson AD, Wolberger C. Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast. The Embo Journal. 19: 3016-27. PMID 10856245 DOI: 10.1093/emboj/19.12.3016  1
2000 Tran HG, Steger DJ, Iyer VR, Johnson AD. The chromo domain protein chd1p from budding yeast is an ATP-dependent chromatin-modifying factor. The Embo Journal. 19: 2323-31. PMID 10811623 DOI: 10.1093/emboj/19.10.2323  1
1999 Hull CM, Johnson AD. Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science (New York, N.Y.). 285: 1271-5. PMID 10455055 DOI: 10.1126/science.285.5431.1271  1
1997 Redd MJ, Arnaud MB, Johnson AD. A complex composed of tup1 and ssn6 represses transcription in vitro. The Journal of Biological Chemistry. 272: 11193-7. PMID 9111019 DOI: 10.1074/jbc.272.17.11193  1
1996 Redd MJ, Stark MR, Johnson AD. Accessibility of alpha 2-repressed promoters to the activator Gal4. Molecular and Cellular Biology. 16: 2865-9. PMID 8649396  1
1995 Smith RL, Redd MJ, Johnson AD. The tetratricopeptide repeats of Ssn6 interact with the homeo domain of alpha 2. Genes & Development. 9: 2903-10. PMID 7498787  1
1994 Komachi K, Redd MJ, Johnson AD. The WD repeats of Tup1 interact with the homeo domain protein alpha 2. Genes & Development. 8: 2857-67. PMID 7995523  1
1992 Keleher CA, Redd MJ, Schultz J, Carlson M, Johnson AD. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell. 68: 709-19. PMID 1739976 DOI: 10.1016/0092-8674(92)90146-4  1
1985 Johnson AD, Herskowitz I. A repressor (MAT alpha 2 Product) and its operator control expression of a set of cell type specific genes in yeast. Cell. 42: 237-47. PMID 3893743 DOI: 10.1016/S0092-8674(85)80119-7  1
1982 Ptashne M, Johnson AD, Pabo CO. A genetic switch in a bacterial virus. Scientific American. 247: 128-30, 132, 134-40. PMID 6216590  0.92
1981 Johnson AD, Poteete AR, Lauer G, Sauer RT, Ackers GK, Ptashne M. lambda Repressor and cro--components of an efficient molecular switch. Nature. 294: 217-23. PMID 6457992  0.92
1980 Ptashne M, Jeffrey A, Johnson AD, Maurer R, Meyer BJ, Pabo CO, Roberts TM, Sauer RT. How the lambda repressor and cro work. Cell. 19: 1-11. PMID 6444544 DOI: 10.1016/0092-8674(80)90383-9  0.92
1979 Johnson AD, Meyer BJ, Ptashne M. Interactions between DNA-bound repressors govern regulation by the lambda phage repressor. Proceedings of the National Academy of Sciences of the United States of America. 76: 5061-5. PMID 159452  0.92
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