John D. Baxter, M.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lin JZ, Martagón AJ, Cimini SL, Gonzalez DD, Tinkey DW, Biter A, Baxter JD, Webb P, Gustafsson JÅ, Hartig SM, Phillips KJ. Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat. Cell Reports. PMID 26586443 DOI: 10.1016/j.celrep.2015.10.022  1
2013 Vatner DF, Weismann D, Beddow SA, Kumashiro N, Erion DM, Liao XH, Grover GJ, Webb P, Phillips KJ, Weiss RE, Bogan JS, Baxter J, Shulman GI, Samuel VT. Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. American Journal of Physiology. Endocrinology and Metabolism. 305: E89-100. PMID 23651850 DOI: 10.1152/ajpendo.00573.2012  1
2013 Yuan C, Nguyen P, Baxter JD, Webb P. Distinct ligand-dependent and independent modes of thyroid hormone receptor (TR)/PGC-1α interaction. The Journal of Steroid Biochemistry and Molecular Biology. 133: 58-65. PMID 22974658 DOI: 10.1016/j.jsbmb.2012.09.001  1
2012 Lin JZ, Martagón AJ, Hsueh WA, Baxter JD, Gustafsson JÅ, Webb P, Phillips KJ. Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor. Endocrinology. 153: 6136-44. PMID 23087171 DOI: 10.1210/en.2011-2081  1
2012 Grosdidier S, Carbó LR, Buzón V, Brooke G, Nguyen P, Baxter JD, Bevan C, Webb P, Estébanez-Perpiñá E, Fernández-Recio J. Allosteric conversation in the androgen receptor ligand-binding domain surfaces Molecular Endocrinology. 26: 1078-1090. PMID 22653923 DOI: 10.1210/me.2011-1281  1
2012 Amato AA, Rajagopalan S, Lin JZ, Carvalho BM, Figueira AC, Lu J, Ayers SD, Mottin M, Silveira RL, Souza PC, Mourão RH, Saad MJ, Togashi M, Simeoni LA, Abdalla DS, ... ... Baxter JD, et al. GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain. The Journal of Biological Chemistry. 287: 28169-79. PMID 22584573 DOI: 10.1074/jbc.M111.332106  1
2012 Xiao R, Sun D, Ayers S, Xi Y, Li W, Baxter JD, Moore DD. Research resource: The estrogen receptor α cistrome defined by damIP Molecular Endocrinology. 26: 349-357. PMID 22207717 DOI: 10.1210/me.2011-1080  1
2012 Yumoto F, Nguyen P, Sablin EP, Baxter JD, Webb P, Fletterick RJ. Structural basis of coactivation of liver receptor homolog-1 by β-catenin. Proceedings of the National Academy of Sciences of the United States of America. 109: 143-8. PMID 22187462 DOI: 10.1073/pnas.1117036108  1
2012 Yuan C, Lin JZH, Sieglaff DH, Ayers SD, DeNoto-Reynolds F, Baxter JD, Webb P. Identical gene regulation patterns of T 3and selective thyroid hormone receptor modulator GC-1 Endocrinology. 153: 501-511. PMID 22067320 DOI: 10.1210/en.2011-1325  1
2011 Saunier EF, Vivar OI, Rubenstein A, Zhao X, Olshansky M, Baggett S, Staub RE, Tagliaferri M, Cohen I, Speed TP, Baxter JD, Leitman DC. Estrogenic plant extracts reverse weight gain and fat accumulation without causing mammary gland or uterine proliferation. Plos One. 6: e28333. PMID 22163294 DOI: 10.1371/journal.pone.0028333  1
2011 Deng T, Sieglaff DH, Zhang A, Lyon CJ, Ayers SD, Cvoro A, Gupte AA, Xia X, Baxter JD, Webb P, Hsueh WA. A peroxisome proliferator-activated receptor γ (PPARγ)/ PPARγ coactivator 1β autoregulatory loop in adipocyte mitochondrial function Journal of Biological Chemistry. 286: 30723-30731. PMID 21719705 DOI: 10.1074/jbc.M111.251926  1
2011 Figueira ACM, Saidemberg DM, Souza PCT, Martínez L, Scanlan TS, Baxter JD, Skaf MS, Palma MS, Webb P, Polikarpov I. Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange Molecular Endocrinology. 25: 15-31. PMID 21106879 DOI: 10.1210/me.2010-0202  1
2010 Gupte AA, Liu JZ, Ren Y, Minze LJ, Wiles JR, Collins AR, Lyon CJ, Pratico D, Finegold MJ, Wong ST, Webb P, Baxter JD, Moore DD, Hsueh WA. Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice. Hepatology (Baltimore, Md.). 52: 2001-11. PMID 20938947 DOI: 10.1002/hep.23941  1
2010 Ladenson PW, Kristensen JD, Ridgway EC, Olsson AG, Carlsson B, Klein I, Baxter JD, Angelin B. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. The New England Journal of Medicine. 362: 906-16. PMID 20220185 DOI: 10.1056/NEJMoa0905633  1
2010 Ladenson PW, Kristensen JD, Ridgway EC, Olsson AG, Carlsson B, Klein I, Baxter JD, Angelin B. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia Obstetrical and Gynecological Survey. 65: 512-513. DOI: 10.1097/OGX.0b013e3181f07bed  1
2009 Martínez L, Nascimento AS, Nunes FM, Phillips K, Aparicio R, Dias SMG, Figueira ACM, Lin JH, Nguyen P, Apriletti JW, Neves FAR, Baxter JD, Webb P, Skaf MS, Polikarpov I. Gaining ligand selectivity in thyroid hormone receptors via entropy Proceedings of the National Academy of Sciences of the United States of America. 106: 20717-20722. PMID 19926848 DOI: 10.1073/pnas.0911024106  1
2009 Govindan M, Meng X, Denis CL, Webb P, Baxter JD, Walfish PG. Identification of CCR4 and other essential thyroid hormone receptor co-activators by modified yeast synthetic genetic array analysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 19854-9. PMID 19903885 DOI: 10.1073/pnas.0910134106  1
2009 Cunha Lima ST, Nguyen NH, Togashi M, Apriletti JW, Nguyen P, Polikarpov I, Scanlan TS, Baxter JD, Webb P. Differential effects of TR ligands on hormone dissociation rates: Evidence for multiple ligand entry/exit pathways Journal of Steroid Biochemistry and Molecular Biology. 117: 125-131. PMID 19729063 DOI: 10.1016/j.jsbmb.2009.08.003  1
2009 Baxter JD, Webb P. Thyroid hormone mimetics: Potential applications in atherosclerosis, obesity and type 2 diabetes Nature Reviews Drug Discovery. 8: 308-320. PMID 19337272 DOI: 10.1038/nrd2830  1
2009 Jouravel N, Sablin E, Togashi M, Baxter JD, Webb P, Fletterick RJ. Molecular basis for dimer formation of TRbeta variant D355R. Proteins. 75: 111-7. PMID 18798561 DOI: 10.1002/prot.22225  1
2008 Shah V, Nguyen P, Nguyen NH, Togashi M, Scanlan TS, Baxter JD, Webb P. Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines Molecular and Cellular Endocrinology. 296: 69-77. PMID 18930112 DOI: 10.1016/j.mce.2008.09.016  1
2008 Bryzgalova G, Effendic S, Khan A, Rehnmark S, Barbounis P, Boulet J, Dong G, Singh R, Shapses S, Malm J, Webb P, Baxter JD, Grover GJ. Anti-obesity, anti-diabetic, and lipid lowering effects of the thyroid receptor beta subtype selective agonist KB-141. The Journal of Steroid Biochemistry and Molecular Biology. 111: 262-7. PMID 18621127 DOI: 10.1016/j.jsbmb.2008.06.010  1
2008 Jeyakumar M, Webb P, Baxter JD, Scanlan TS, Katzenellenbogen JA. Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor. Biochemistry. 47: 7465-76. PMID 18558711 DOI: 10.1021/bi800393u  1
2008 Bleicher L, Aparicio R, Nunes FM, Martinez L, Gomes Dias SM, Figueira ACM, Santos MAM, Venturelli WH, Da Silva R, Donate PM, Neves FAR, Simeoni LA, Baxter JD, Webb P, Skaf MS, et al. Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms Bmc Structural Biology. 8. PMID 18237438 DOI: 10.1186/1472-6807-8-8  1
2008 Berkenstam A, Kristensen J, Mellström K, Carlsson B, Malm J, Rehnmark S, Garg N, Andersson CM, Rudling M, Sjöberg F, Angelin B, Baxter JD. The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans Proceedings of the National Academy of Sciences of the United States of America. 105: 663-667. PMID 18160532 DOI: 10.1073/pnas.0705286104  1
2007 Estébanez-Perpiñá E, Arnold LA, Jouravel N, Togashi M, Blethrow J, Mar E, Nguyen P, Phillips KJ, Baxter JD, Webb P, Guy RK, Fletterick RJ. Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Molecular Endocrinology (Baltimore, Md.). 21: 2919-28. PMID 17823305 DOI: 10.1210/me.2007-0174  1
2007 Velasco LFR, Togashi M, Walfish PG, Pessanha RP, Moura FN, Barra GB, Nguyen P, Rebong R, Yuan C, Simeoni LA, Ribeiro RCJ, Baxter JD, Webb P, Neves FAR. Thyroid hormone response element organization dictates the composition of active receptor Journal of Biological Chemistry. 282: 12458-12466. PMID 17311926 DOI: 10.1074/jbc.M610700200  1
2007 Figueira ACM, Neto MDO, Bernardes A, Dias SMG, Craievich AF, Baxter JD, Webb P, Polikarpov I. Low-resolution structures of thyroid hormone receptor dimers and tetramers in solution Biochemistry. 46: 1273-1283. PMID 17260956 DOI: 10.1021/bi061698h  1
2006 Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennström B, Samarut J. International union of pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: Thyroid hormone receptors Pharmacological Reviews. 58: 705-711. PMID 17132849 DOI: 10.1124/pr.58.4.3  1
2006 Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding. Science's Stke : Signal Transduction Knowledge Environment. 2006: pl3. PMID 16804159 DOI: 10.1126/stke.3412006pl3  1
2006 Nascimento AS, Dias SMG, Nunes FM, Aparício R, Ambrosio ALB, Bleicher L, Figueira ACM, Santos MAM, Neto MdO, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, et al. Structural Rearrangements in the Thyroid Hormone Receptor Hinge Domain and Their Putative Role in the Receptor Function Journal of Molecular Biology. 360: 586-598. PMID 16781732 DOI: 10.1016/j.jmb.2006.05.008  1
2006 Figueira ACM, Dias SMG, Santos MAM, Apriletti JW, Baxter JD, Webb P, Neves FAR, Simeoni LA, Ribeiro RCJ, Polikarpov I. Human thyroid receptor forms tetramers in solution, which dissociate into dimers upon ligand binding Cell Biochemistry and Biophysics. 44: 453-462. PMID 16679533 DOI: 10.1385/CBB:44:3:453  1
2006 Baxter JD, Webb P. Metabolism: Bile acids heat things up Nature. 439: 402-403. PMID 16437098 DOI: 10.1038/439402a  1
2005 Arnold LA, Estébanez-Perpiñá E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators. The Journal of Biological Chemistry. 280: 43048-55. PMID 16263725 DOI: 10.1074/jbc.M506693200  1
2005 Gloss B, Giannocco G, Swanson EA, Moriscot AS, Chiellini G, Scanlan T, Baxter JD, Dillmann WH. Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression Endocrinology. 146: 4926-4933. PMID 16081636 DOI: 10.1210/en.2005-0631  1
2005 Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P. Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice Proceedings of the National Academy of Sciences of the United States of America. 102: 10297-10302. PMID 16006512 DOI: 10.1073/pnas.0504379102  1
2005 Martínez L, Sonoda MT, Webb P, Baxter JD, Skaf MS, Polikarpov I. Molecular dynamics simulations reveal multiple pathways of ligand dissociation from thyroid hormone receptors Biophysical Journal. 89: 2011-2023. PMID 15980170 DOI: 10.1529/biophysj.105.063818  1
2005 Togashi M, Nguyen P, Fletterick R, Baxter JD, Webb P. Rearrangements in thyroid hormone receptor charge clusters that stabilize bound 3,5′,5-triiodo-L-thyronine and inhibit homodimer formation Journal of Biological Chemistry. 280: 25665-25673. PMID 15886199 DOI: 10.1074/jbc.M501615200  1
2005 Togashi M, Borngraeber S, Sandler B, Fletterick RJ, Webb P, Baxter JD. Conformational adaptation of nuclear receptor ligand binding domains to agonists: potential for novel approaches to ligand design. The Journal of Steroid Biochemistry and Molecular Biology. 93: 127-37. PMID 15860255 DOI: 10.1016/j.jsbmb.2005.01.004  1
2005 Meng X, Webb P, Yang YF, Shuen M, Yousef AF, Baxter JD, Mymryk JS, Walfish PG. E1A and a nuclear receptor corepressor splice variant (N-CoRI) are thyroid hormone receptor coactivators that bind in the corepressor mode Proceedings of the National Academy of Sciences of the United States of America. 102: 6267-6272. PMID 15849266 DOI: 10.1073/pnas.0501491102  1
2005 Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists Journal of the American Chemical Society. 127: 4599-4608. PMID 15796525 DOI: 10.1021/ja0440093  1
2005 Estébanez-Perpiñá E, Moore JM, Mar E, Delgado-Rodrigues E, Nguyen P, Baxter JD, Buehrer BM, Webb P, Fletterick RJ, Guy RK. The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor. The Journal of Biological Chemistry. 280: 8060-8. PMID 15563469 DOI: 10.1074/jbc.M407046200  1
2004 Sandler B, Webb P, Apriletti JW, Huber BR, Togashi M, Cunha Lima ST, Juric S, Nilsson S, Wagner R, Fletterick RJ, Baxter JD. Thyroxine-thyroid hormone receptor interactions. The Journal of Biological Chemistry. 279: 55801-8. PMID 15466465 DOI: 10.1074/jbc.M410124200  1
2004 Rodrigues MC, Santos GM, da Silva CA, Baxter JD, Webb P, Lomri N, Neves FA, Ribeiro RC, Simeoni LA. Thyroid hormone transport is disturbed in erythrocytes from patients with chronic renal failure on hemodialysis. Renal Failure. 26: 461-6. PMID 15462116 DOI: 10.1081/JDI-200026760  1
2004 Nunes FM, Aparicio R, Santos MAM, Portugal RV, Dias SMG, Neves FAR, Simeoni LA, Baxter JD, Webb P, Polikarpov I. Crystallization and preliminary X-ray diffraction studies of isoform α1 of the human thyroid hormone receptor ligand-binding domain Acta Crystallographica Section D: Biological Crystallography. 60: 1867-1870. PMID 15388935 DOI: 10.1107/S0907444904017858  1
2004 Baxter JD, Funder JW, Apriletti JW, Webb P. Towards selectively modulating mineralocorticoid receptor function: lessons from other systems. Molecular and Cellular Endocrinology. 217: 151-65. PMID 15134814 DOI: 10.1016/j.mce.2003.10.044  1
2004 Baxter JD, Webb P, Grover G, Scanlan TS. Selective activation of thyroid hormone signaling pathways by GC-1: A new approach to controlling cholesterol and body weight Trends in Endocrinology and Metabolism. 15: 154-157. PMID 15109613 DOI: 10.1016/j.tem.2004.03.008  1
2004 Dupré SM, Guissouma H, Flamant F, Seugnet I, Scanlan TS, Baxter JD, Samarut J, Demeneix BA, Becker N. Both thyroid hormone receptor (TR)β1 and TRβ2 isoforms contribute to the regulation of hypothalamic Thyrotropin-Releasing Hormone Endocrinology. 145: 2337-2345. PMID 14726446 DOI: 10.1210/en.2003-1209  1
2004 Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS. Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: Selective actions relative to 3,5,3′-triiodo-L-thyronine Endocrinology. 145: 1656-1661. PMID 14701670 DOI: 10.1210/en.2003-0973  1
2003 Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, Fletterick RJ. Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15358-63. PMID 14673100 DOI: 10.1073/pnas.2136689100  1
2003 Webb P, Valentine C, Nguyen P, Price RH, Marimuthu A, West BL, Baxter JD, Kushner PJ. ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus. Nuclear Receptor. 1: 4. PMID 12904255 DOI: 10.1186/1478-1336-1-4  1
2003 Grover GJ, Mellström K, Ye L, Malm J, Li YL, Bladh LG, Sleph PG, Smith MA, George R, Vennström B, Mookhtiar K, Horvath R, Speelman J, Egan D, Baxter JD. Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability. Proceedings of the National Academy of Sciences of the United States of America. 100: 10067-72. PMID 12888625 DOI: 10.1073/pnas.1633737100  1
2003 Yoshihara HA, Apriletti JW, Baxter JD, Scanlan TS. Structural determinants of selective thyromimetics. Journal of Medicinal Chemistry. 46: 3152-61. PMID 12825953 DOI: 10.1021/jm0301181  1
2003 Baxter JD, Young WF, Webb P. Cardiovascular endocrinology: introduction. Endocrine Reviews. 24: 253-60. PMID 12788796 DOI: 10.1210/er.2003-0099  1
2003 Huber BR, Sandler B, West BL, Cunha Lima ST, Nguyen HT, Apriletti JW, Baxter JD, Fletterick RJ. Two resistance to thyroid hormone mutants with impaired hormone binding. Molecular Endocrinology (Baltimore, Md.). 17: 643-52. PMID 12554782 DOI: 10.1210/me.2002-0095  1
2003 Fischer H, Dias SM, Santos MA, Alves AC, Zanchin N, Craievich AF, Apriletti JW, Baxter JD, Webb P, Neves FA, Ribeiro RC, Polikarpov I. Low resolution structures of the retinoid X receptor DNA-binding and ligand-binding domains revealed by synchrotron X-ray solution scattering. The Journal of Biological Chemistry. 278: 16030-8. PMID 12533536 DOI: 10.1074/jbc.M206953200  1
2003 Huber BR, Desclozeaux M, West BL, Cunha-Lima ST, Nguyen HT, Baxter JD, Ingraham HA, Fletterick RJ. Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain. Molecular Endocrinology (Baltimore, Md.). 17: 107-16. PMID 12511610 DOI: 10.1210/me.2002-0097  1
2002 Webb P, Nguyen NH, Chiellini G, Yoshihara HA, Cunha Lima ST, Apriletti JW, Ribeiro RC, Marimuthu A, West BL, Goede P, Mellstrom K, Nilsson S, Kushner PJ, Fletterick RJ, Scanlan TS, ... Baxter JD, et al. Design of thyroid hormone receptor antagonists from first principles. The Journal of Steroid Biochemistry and Molecular Biology. 83: 59-73. PMID 12650702 DOI: 10.1016/S0960-0760(02)00270-4  1
2002 Nguyen NH, Apriletti JW, Cunha Lima ST, Webb P, Baxter JD, Scanlan TS. Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. Journal of Medicinal Chemistry. 45: 3310-20. PMID 12109914 DOI: 10.1021/jm0201013  1
2002 Weatherman RV, Chang CY, Clegg NJ, Carroll DC, Day RN, Baxter JD, McDonnell DP, Scanlan TS, Schaufele F. Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. Molecular Endocrinology (Baltimore, Md.). 16: 487-96. PMID 11875107 DOI: 10.1210/mend.16.3.0813  1
2002 Marimuthu A, Feng W, Tagami T, Nguyen H, Jameson JL, Fletterick RJ, Baxter JD, West BL. TR surfaces and conformations required to bind nuclear receptor corepressor. Molecular Endocrinology (Baltimore, Md.). 16: 271-86. PMID 11818500 DOI: 10.1210/mend.16.2.0777  1
2002 Baxter JD, Goede P, Apriletti JW, West BL, Feng W, Mellstrom K, Fletterick RJ, Wagner RL, Kushner PJ, Ribeiro RC, Webb P, Scanlan TS, Nilsson S. Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist. Endocrinology. 143: 517-24. PMID 11796506 DOI: 10.1210/endo.143.2.8617  1
2002 Neves FA, Cavalieri RR, Simeoni LA, Gardner DG, Baxter JD, Scharschmidt BF, Lomri N, Ribeiro RC. Thyroid hormone export varies among primary cells and appears to differ from hormone uptake. Endocrinology. 143: 476-83. PMID 11796501 DOI: 10.1210/endo.143.2.8631  1
2002 Chiellini G, Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives. Bioorganic & Medicinal Chemistry. 10: 333-46. PMID 11741782 DOI: 10.1016/S0968-0896(01)00284-X  1
2001 Yoshihara HA, Apriletti JW, Baxter JD, Scanlan TS. A designed antagonist of the thyroid hormone receptor. Bioorganic & Medicinal Chemistry Letters. 11: 2821-5. PMID 11597408  1
2001 Kinugawa K, Yonekura K, Ribeiro RCJ, Eto Y, Aoyagi T, Baxter JD, Camacho SA, Bristow MR, Long CS, Simpson PC. Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy Circulation Research. 89: 591-598. PMID 11577024  1
2001 Baxter JD, Dillmann WH, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS. Selective modulation of thyroid hormone receptor action. The Journal of Steroid Biochemistry and Molecular Biology. 76: 31-42. PMID 11384861 DOI: 10.1016/S0960-0760(01)00052-8  1
2001 Wagner RL, Huber BR, Shiau AK, Kelly A, Cunha Lima ST, Scanlan TS, Apriletti JW, Baxter JD, West BL, Fletterick RJ. Hormone selectivity in thyroid hormone receptors. Molecular Endocrinology (Baltimore, Md.). 15: 398-410. PMID 11222741 DOI: 10.1210/mend.15.3.0608  1
2001 Kinugawa K, Minobe WA, Wood WM, Ridgway EC, Baxter JD, Ribeiro RCJ, Tawadrous MF, Lowes BA, Long CS, Bristow MR. Signaling pathways responsible for fetal gene induction in the failing human heart: Evidence for altered thyroid hormone receptor gene expression Circulation. 103: 1089-1094. PMID 11222471  1
2001 Ribeiro RC, Feng W, Wagner RL, Costa CH, Pereira AC, Apriletti JW, Fletterick RJ, Baxter JD. Definition of the surface in the thyroid hormone receptor ligand binding domain for association as homodimers and heterodimers with retinoid X receptor. The Journal of Biological Chemistry. 276: 14987-95. PMID 11145963 DOI: 10.1074/jbc.M010195200  1
2000 Schaufele F, Chang Cy, Liu W, Baxter JD, Nordeen SK, Wan Y, Day RN, McDonnell DP. Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor Molecular Endocrinology. 14: 2024-2039. PMID 11117532 DOI: 10.1210/me.14.12.2024  1
2000 Webb P, Anderson CM, Valentine C, Nguyen P, Marimuthu A, West BL, Baxter JD, Kushner PJ. The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs) Molecular Endocrinology. 14: 1976-1985. PMID 11117528 DOI: 10.1210/me.14.12.1976  1
2000 Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH. The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology. 141: 3057-64. PMID 10965874 DOI: 10.1210/endo.141.9.7681  1
2000 Baxter JD. Advances in glucocorticoid therapy Advances in Internal Medicine. 45: 317-349. PMID 10635054  1
1999 An J, Ribeiro RCJ, Webb P, Gustafsson JA, Kushner PJ, Baxter JD, Leitman DC. Estradiol repression of tumor necrosis factor-α transcription requires estrogen receptor activation function-2 and is enhanced by coactivators Proceedings of the National Academy of Sciences of the United States of America. 96: 15161-15166. PMID 10611355 DOI: 10.1073/pnas.96.26.15161  1
1999 Cavalieri RR, Simeoni LA, Park SW, Baxter JD, Scharschmidt BF, Ribeiro RCJ, Lomri N. Thyroid hormone export in rat FRTL-5 thyroid cells and mouse NIH-3T3 cells is carrier-mediated, verapamil-sensitive, and stereospecific Endocrinology. 140: 4948-4954. PMID 10537118  1
1999 Duncan KG, Bailey KR, Baxter JD, Schwartz DM. The human fetal retinal pigment epithelium: A target tissue for thyroid hormones Ophthalmic Research. 31: 399-406. PMID 10474068 DOI: 10.1159/000055564  1
1999 Lopez GN, Webb P, Shinsako JH, Baxter JD, Greene GL, Kushner PJ. Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators Molecular Endocrinology. 13: 897-909. PMID 10379889  1
1999 Duncan KG, Jumper MD, Ribeiro RCJ, Bailey KR, Yen PM, Sugawara A, Patel A, Stern R, Chin WW, Baxter JD, Schwartz DM. Human trabecular meshwork cells as a thyroid hormone target tissue: Presence of functional thyroid hormone receptors Graefe's Archive For Clinical and Experimental Ophthalmology. 237: 231-240. PMID 10090587 DOI: 10.1007/s004170050224  1
1998 Apriletti JW, Ribeiro RC, Wagner RL, Feng W, Webb P, Kushner PJ, West BL, Nilsson S, Scanlan TS, Fletterick RJ, Baxter JD. Molecular and structural biology of thyroid hormone receptors. Clinical and Experimental Pharmacology & Physiology. Supplement. 25: S2-11. PMID 9809185  1
1998 Darimont BD, Wagner RL, Apriletti JW, Stallcup MR, Kushner PJ, Baxter JD, Fletterick RJ, Yamamoto KR. Structure and specificity of nuclear receptor-coactivator interactions. Genes & Development. 12: 3343-56. PMID 9808622  1
1998 Ribeiro RC, Apriletti JW, Wagner RL, West BL, Feng W, Huber R, Kushner PJ, Nilsson S, Scanlan T, Fletterick RJ, Schaufele F, Baxter JD. Mechanisms of thyroid hormone action: insights from X-ray crystallographic and functional studies. Recent Progress in Hormone Research. 53: 351-92; discussion 3. PMID 9769715  1
1998 Ribeiro RC, Apriletti JW, Wagner RL, Feng W, Kushner PJ, Nilsson S, Scanlan TS, West BL, Fletterick RJ, Baxter JD. X-ray crystallographic and functional studies of thyroid hormone receptor. The Journal of Steroid Biochemistry and Molecular Biology. 65: 133-41. PMID 9699866 DOI: 10.1016/S0960-0760(98)00029-6  1
1998 Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chemistry & Biology. 5: 299-306. PMID 9653548  1
1998 Feng W, Ribeiro RC, Wagner RL, Nguyen H, Apriletti JW, Fletterick RJ, Baxter JD, Kushner PJ, West BL. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science (New York, N.Y.). 280: 1747-9. PMID 9624051 DOI: 10.1126/science.280.5370.1747  1
1998 Zhang YH, Guo W, Wagner RL, Huang BL, McCabe L, Vilain E, Burris TP, Anyane-Yeboa K, Burghes AH, Chitayat D, Chudley AE, Genel M, Gertner JM, Klingensmith GJ, Levine SN, ... ... Baxter JD, et al. DAX1 mutations map to putative structural domains in a deduced three-dimensional model. American Journal of Human Genetics. 62: 855-64. PMID 9529340 DOI: 10.1086/301782  1
1997 Chuang FM, West BL, Baxter JD, Schaufele F. Activities in Pit-1 determine whether receptor interacting protein 140 activates or inhibits Pit-1/nuclear receptor transcriptional synergy Molecular Endocrinology. 11: 1332-1341. PMID 9259323 DOI: 10.1210/me.11.9.1332  1
1997 Saatcioglu F, Lopez G, West BL, Zandi E, Feng W, Lu H, Esmaili A, Apriletti JW, Kushner PJ, Baxter JD, Karin M. Mutations in the conserved C-terminal sequence in thyroid hormone receptor dissociate hormone-dependent activation from interference with AP-1 activity. Molecular and Cellular Biology. 17: 4687-95. PMID 9234725  1
1996 Leitman DC, Costa CHRM, Graf H, Baxter JD, Ribeiro RCJ. Thyroid hormone activation of transcription is potentiated by activators of cAMP-dependent protein kinase Journal of Biological Chemistry. 271: 21950-21955. PMID 8703000 DOI: 10.1074/jbc.271.36.21950  1
1996 Brechler V, Chu WN, Baxter JD, Thibault G, Reudelhuber TL. A protease processing site is essential for prorenin sorting to the regulated secretory pathway Journal of Biological Chemistry. 271: 20636-20640. PMID 8702811 DOI: 10.1074/jbc.271.34.20636  1
1996 Chang W, Zhou W, Theill LE, Baxter JD, Schaufele F. An activation function in Pit-1 required selectively for synergistic transcription Journal of Biological Chemistry. 271: 17733-17738. PMID 8663468 DOI: 10.1074/jbc.271.30.17733  1
1996 Ribeiro RCJ, Cavalieri RR, Lomri N, Rahmaoui CM, Baxter JD, Scharschmidt BF. Thyroid hormone export regulates cellular hormone content and response Journal of Biological Chemistry. 271: 17147-17151. PMID 8663353 DOI: 10.1074/jbc.271.29.17147  1
1996 Neves FAR, Duncan KG, Baxter JD. Cathepsin B is a prorenin processing enzyme Hypertension. 27: 514-517. PMID 8613195  1
1995 Sadovsky Y, Webb P, Lopez G, Baxter JD, Fitzpatrick PM, Gizang-Ginsberg E, Cavailles V, Parker MG, Kushner PJ. Transcriptional activators differ in their responses to overexpression of TATA-box-binding protein. Molecular and Cellular Biology. 15: 1554-63. PMID 7862148  1
1995 Ribeiro RC, Apriletti JW, West BL, Wagner RL, Fletterick RJ, Schaufele F, Baxter JD. The molecular biology of thyroid hormone action. Annals of the New York Academy of Sciences. 758: 366-89. PMID 7625705 DOI: 10.1111/j.1749-6632.1995.tb24843.x  1
1995 Ribeiro RCJ, Kushner PJ, Baxter JD. The nuclear hormone receptor gene superfamily Annual Review of Medicine. 46: 443-453. PMID 7598477 DOI: 10.1146/annurev.med.46.1.443  1
1995 Ortiz JM, Kamerling JM, Fischer D, Baxter J. Scleritis, uveitis, and glaucoma in a patient with rheumatic fever American Journal of Ophthalmology. 120: 538-539. PMID 7573320  1
1995 Wagner RL, Apriletti JW, McGrath ME, West BL, Baxter JD, Fletterick RJ. A structural role for hormone in the thyroid hormone receptor. Nature. 378: 690-7. PMID 7501015 DOI: 10.1038/378690a0  1
1992 Martial JA, Hallewell RA, Baxter JD, Goodman HM. Human growth hormone: complementary DNA cloning and expression in bacteria. 1979. Biotechnology (Reading, Mass.). 24: 293-8. PMID 1422028  1
1984 Karin M, Eberhardt NL, Mellon SH, Malich N, Richards RI, Slater EP, Barta A, Martial JA, Baxter JD, Cathala G. Expression and hormonal regulation of the rat growth hormone gene in transfected mouse L cells. Dna (Mary Ann Liebert, Inc.). 3: 147-55. PMID 6723496  1
1983 Cathala G, Savouret JF, Mendez B, West BL, Karin M, Martial JA, Baxter JD. A method for isolation of intact, translationally active ribonucleic acid. Dna (Mary Ann Liebert, Inc.). 2: 329-35. PMID 6198133  0.44
1982 Wegnez M, Schachter BS, Baxter JD, Martial JA. Hormonal regulation of growth hormone mRNA. Dna (Mary Ann Liebert, Inc.). 1: 145-53. PMID 6897720  1
1982 Lan NC, Nguyen T, Cathala G, Wolff ME, Kollman PA, Wegnez M, Martial JA, Baxter JD. Molecular mechanisms of glucocorticoid hormone action. Journal of Molecular and Cellular Cardiology. 14: 43-8. PMID 6754955 DOI: 10.1016/0022-2828(82)90128-6  1
1981 Miller WL, Coit D, Baxter JD, Martial JA. Cloning of bovine prolactin cDNA and evolutionary implications of its sequence. Dna (Mary Ann Liebert, Inc.). 1: 37-50. PMID 6299665  1
1981 Cooke NE, Coit D, Shine J, Baxter JD, Martial JA. Human prolactin. cDNA structural analysis and evolutionary comparisons. The Journal of Biological Chemistry. 256: 4007-16. PMID 6260780  1
1980 Mendez B, Valenzuela P, Martial JA, Baxter JD. Cell-free synthesis of acetylcholine receptor polypeptides. Science (New York, N.Y.). 209: 695-7. PMID 7394526  1
1980 Owerbach D, Rutter WJ, Martial JA, Baxter JD, Shows TB. Genes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans. Science (New York, N.Y.). 209: 289-92. PMID 7384802 DOI: 10.1126/science.7384802  1
1980 Cooke NE, Coit D, Weiner RI, Baxter JD, Martial JA. Structure of cloned DNA complementary to rat prolactin messenger RNA. The Journal of Biological Chemistry. 255: 6502-10. PMID 6993473  1
1980 Miller WL, Martial JA, Baxter JD. Molecular cloning of DNA complementary to bovine growth hormone mRNA. The Journal of Biological Chemistry. 255: 7521-4. PMID 6893197  1
1979 Martial JA, Seeburg PH, Matulich DT, Goodman HM, Baxter JD. Regulation of growth hormone messenger RNA. Monographs On Endocrinology. 12: 279-89. PMID 492172  1
1979 Martial JA, Hallewell RA, Baxter JD, Goodman HM. Human growth hormone: complementary DNA cloning and expression in bacteria. Science (New York, N.Y.). 205: 602-7. PMID 377496  1
1979 Baxter JD, Eberhardt NL, Apriletti JW, Johnson LK, Ivarie RD, Schachter BS, Morris JA, Seeburg PH, Goodman HM, Latham KR, Polansky JR, Martial JA. Thyroid hormone receptors and responses. Recent Progress in Hormone Research. 35: 97-153. PMID 229530  1
1978 Seeburg PH, Shine J, Martial JA, Ivarie RD, Morris JA, Ullrich A, Baxter JD, Goodman HM. Synthesis of growth hormone by bacteria. Nature. 276: 795-8. PMID 364320 DOI: 10.1038/276795a0  1
1977 Seeburg PH, Shine J, Martial JA, Ullrich A, Goodman HM, Baxter JD. Nucleotide sequence of a human gene coding for a polypeptide hormone. Transactions of the Association of American Physicians. 90: 109-16. PMID 611657  1
1977 Shine J, Seeburg PH, Martial JA, Baxter JD, Goodman HM. Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature. 270: 494-9. PMID 593368 DOI: 10.1038/270494a0  1
1977 Seeburg PH, Shine J, Martial JA, Baxter JD, Goodman HM. Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature. 270: 486-94. PMID 339105 DOI: 10.1038/270486a0  1
1977 Martial JA, Seeburg PH, Guenzi D, Goodman HM, Baxter JD. Regulation of growth hormone gene expression: synergistic effects of thyroid and glucocorticoid hormones. Proceedings of the National Academy of Sciences of the United States of America. 74: 4293-5. PMID 270674  1
1977 Martial JA, Baxter JD, Goodman HM, Seeburg PH. Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones. Proceedings of the National Academy of Sciences of the United States of America. 74: 1816-20. PMID 266704  1
1977 Papavasiliou SS, Martial JA, Latham KR, Baxter JD. Thyroid hormonelike actions of 3,3',5'-L-triiodothyronine nad 3,3'-diiodothyronine. The Journal of Clinical Investigation. 60: 1230-9. PMID 199617 DOI: 10.1172/JCI108882  1
1977 Seeburg PH, Shine J, Martial JA, Ullrich A, Baxter JD, Goodman HM. Nucleotide sequence of part of the gene for human chorionic somatomammotropin: purification of DNA complementary to predominant mRNA species. Cell. 12: 157-65. PMID 71212  0.44
1976 Simons SS, Martinez HM, Garcea RL, Baxter JD, Tomkins GM. Interaction of glucocorticoid receptor-steroid complexes with acceptor sites. The Journal of Biological Chemistry. 251: 334-43. PMID 173716  1
1975 Rousseau GG, Higgins SJ, Baxter JD, Gelfand D, Tomkins GM. Binding of glucocorticoid receptors to DNA. The Journal of Biological Chemistry. 250: 6015-21. PMID 168206  1
1974 Ballard PL, Baxter JD, Higgins SJ, Rousseau GG, Tomkins GM. General presence of glucocorticoid receptors in mammalian tissues. Endocrinology. 94: 998-1002. PMID 4362047 DOI: 10.1210/endo-94-4-998  1
1973 Higgins SJ, Rousseau GG, Baxter JD, Tomkins GM. Nuclear binding of steroid receptors: comparison in intact cells and cell-free systems. Proceedings of the National Academy of Sciences of the United States of America. 70: 3415-8. PMID 4357870  1
1973 Higgins SJ, Rousseau GG, Baxter JD, Tomkins GM. Nature of nuclear acceptor sites for glucocorticoid- and estrogen-receptor complexes. The Journal of Biological Chemistry. 248: 5873-9. PMID 4353280  1
1973 Higgins SJ, Rousseau GG, Baxter JD, Tomkins GM. Early events in glucocorticoid action. Activation of the steroid receptor and its subsequent specific nuclear binding studied in a cell-free system. The Journal of Biological Chemistry. 248: 5866-72. PMID 4353279  1
1973 Santi DV, Sibley CH, Perriard ER, Tomkins GM, Baxter JD. A filter assay for steroid hormone receptors. Biochemistry. 12: 2412-6. PMID 4350952  1
1973 Rousseau GG, Baxter JD, Higgins SJ, Tomkins GM. Steroid-induced nuclear binding of glucocorticoid receptors in intact hepatoma cells. Journal of Molecular Biology. 79: 539-54. PMID 4148423 DOI: 10.1016/0022-2836(73)90405-1  1
1972 Rosenau W, Baxter JD, Rousseau GG, Tomkins GM. Mechanism of resistance to steroids: glucocorticoid receptor defect in lymphoma cells. Nature: New Biology. 237: 20-4. PMID 4503684  1
1972 Tomkins GM, Levinson BB, Baxter JD, Dethlefsen L. Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells. Nature: New Biology. 239: 9-14. PMID 4404031  1
1972 Baxter JD, Rousseau GG, Benson MC, Garcea RL, Ito J, Tomkins GM. Role of DNA and specific cytoplasmic receptors in glucocorticoid action. Proceedings of the National Academy of Sciences of the United States of America. 69: 1892-6. PMID 4403081  1
1972 Rousseau GG, Baxter JD, Tomkins GM. Glucocorticoid receptors: relations between steroid binding and biological effects. Journal of Molecular Biology. 67: 99-115. PMID 4402888 DOI: 10.1016/0022-2836(72)90389-0  1
1972 Rousseau G, Baxter JD, Funder JW, Edelman IS, Tomkins GM. Glucocorticoid and mineralocorticoid receptors for aldosterone. Journal of Steroid Biochemistry. 3: 219-27. PMID 4346760 DOI: 10.1016/0022-4731(72)90053-2  1
1972 Levinson BB, Baxter JD, Rousseau GG, Tomkins GM. Cellular site of glucocorticoid-receptor complex formation. Science (New York, N.Y.). 175: 189-90. PMID 4332760  1
1971 Baxter JD, Tomkins GM. Specific cytoplasmic glucocorticoid hormone receptors in hepatoma tissue culture cells. Proceedings of the National Academy of Sciences of the United States of America. 68: 932-7. PMID 4396919  1
1971 Baxter JD, Harris AW, Tomkins GM, Cohn M. Glucocorticoid receptors in lymphoma cells in culture: relationship to glucocorticoid killing activity. Science (New York, N.Y.). 171: 189-91. PMID 4395230  1
1970 Baxter JD, Tomkins GM. The relationship between glucocorticoid binding and tyrosine aminotransferase induction in hepatoma tissue culture cells. Proceedings of the National Academy of Sciences of the United States of America. 65: 709-15. PMID 4315614  1
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