Geoffrey L. Greene, PhD - Publications

Affiliations: 
Ben May Department for Cancer Research University of Chicago, Chicago, IL 
Area:
breast cancer, steroid hormone action
Website:
http://benmay.uchicago.edu/faculty/greene

204 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lainé M, Greene ME, Kurleto JD, Bozek G, Leng T, Huggins RJ, Komm BS, Greene GL. Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer. Breast Cancer Research : Bcr. 26: 95. PMID 38849889 DOI: 10.1186/s13058-024-01843-4  0.307
2023 Porter BA, Frerich C, Lainé M, Clark AB, Durdana I, Lee J, Taya M, Sahoo S, Greene GL, Bennett L, Conzen SD. Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases. Cancers. 15. PMID 37835373 DOI: 10.3390/cancers15194679  0.344
2023 Huggins RJ, Hosfield D, Ishag-Osman A, Lee K, Ton-That E, Greene GL. Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assay. Biorxiv : the Preprint Server For Biology. PMID 37546915 DOI: 10.1101/2023.07.25.550078  0.351
2022 Ren P, Tiede C, Fanning SW, Adams T, Speirs V, Nelson ER, Cheng C, Moore TW, Greene GL, Tomlinson D, Selvin PR. Labeling of a Mutant Estrogen Receptor with an Affimer in a Breast Cancer Cell Line. Biophysical Journal. PMID 35778844 DOI: 10.1016/j.bpj.2022.06.028  0.31
2022 Hosfield DJ, Weber S, Li NS, Suavage M, Joiner CF, Hancock GR, Sullivan EA, Ndukwe E, Han R, Cush S, Lainé M, Mader SC, Greene GL, Fanning SW. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in mutant breast cancer cells. Elife. 11. PMID 35575456 DOI: 10.7554/eLife.72512  0.404
2021 Mayne CG, Toy W, Carlson KE, Bhatt T, Fanning SW, Greene GL, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA, Tajkhorshid E. Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular Cancer Research : McR. PMID 34021071 DOI: 10.1158/1541-7786.MCR-20-1017  0.375
2021 Lainé M, Fanning SW, Chang YF, Green B, Greene ME, Komm B, Kurleto JD, Phung L, Greene GL. Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer. Breast Cancer Research : Bcr. 23: 54. PMID 33980285 DOI: 10.1186/s13058-021-01431-w  0.342
2020 Abderrahman B, Maximov PY, Curpan RF, Fanning SW, Hanspal JS, Fan P, Foulds CE, Chen Y, Malovannaya A, Jain A, Xiong R, Greene GL, Tonetti DA, Thatcher GRJ, Jordan VC. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Molecular Cancer Therapeutics. PMID 33177154 DOI: 10.1158/1535-7163.MCT-20-0563  0.336
2020 Maximov PY, Abderrahman B, Hawsawi YM, Chen Y, Foulds CE, Jain A, Malovannaya A, Fan P, Curpan RF, Han R, Fanning SW, Broom BM, Quintana Rincon DM, Greenland JA, Greene GL, et al. The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Molecular Pharmacology. PMID 32362585 DOI: 10.1124/Mol.120.119776  0.464
2020 Kastrati I, Joosten SEP, Semina SE, Alejo LH, Brovkovych SD, Stender JD, Horlings HM, Kok M, Alarid ET, Greene GL, Linn SC, Zwart W, Frasor J. The NFκB pathway promotes tamoxifen tolerance and disease recurrence in estrogen receptor positive breast cancers. Molecular Cancer Research : McR. PMID 32245803 DOI: 10.1158/1541-7786.Mcr-19-1082  0.437
2020 Fanning SW, Greene G, Conlan MG. X-ray crystal structure analysis of elacestrant (RAD1901), a novel selective estrogen receptor degrader (SERD), bound to estrogen receptor alpha ligand binding domain. Journal of Clinical Oncology. 38: e15647-e15647. DOI: 10.1200/Jco.2020.38.15_Suppl.E15647  0.484
2020 Gruener RF, Tijerina M, Greene GL, Huang RS. Abstract 6428: Imputing a more selective therapy: Identifying Wee1 and XPO1 inhibitors for TNBC Cancer Research. 80: 6428-6428. DOI: 10.1158/1538-7445.Am2020-6428  0.352
2020 Dembo AG, Aledort ES, Greene GL. Abstract 4374: CE+BZA combination therapy decreases breast cancer outgrowth in part through activation of the AHR pathway Epidemiology. DOI: 10.1158/1538-7445.Am2020-4374  0.353
2020 Laine M, Kurleto JD, Greene ME, Phung L, Komm BS, Greene GL. Abstract 4370: Lasofoxifene alone or in combination with palbociclib as an effective treatment for therapy-resistant ER-positive metastatic breast cancer Epidemiology. DOI: 10.1158/1538-7445.Am2020-4370  0.364
2020 Ren P, Fanning SW, Tiede C, Adams TL, Speirs V, Greene GL, Nelson ER, Tomlinson DC, Selvin PR. Efficient Labeling of Estrogen Receptor α Inside Cells using Affimer, an Antibody Mimetic Biophysical Journal. 118: 470a. DOI: 10.1016/J.Bpj.2019.11.2607  0.356
2019 Cocce KJ, Jasper JS, Desautels TK, Everett L, Wardell S, Westerling T, Baldi R, Wright TM, Tavares K, Yllanes A, Bae Y, Blitzer JT, Logsdon C, Rakiec DP, Ruddy DA, ... ... Greene GL, et al. The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Reports. 29: 889-903.e10. PMID 31644911 DOI: 10.1016/J.Celrep.2019.09.032  0.396
2019 Fanning SW, Greene GL. Next Generation ERα Inhibitors for Endocrine-Resistant ER+ Breast Cancers. Endocrinology. PMID 30753408 DOI: 10.1210/En.2018-01095  0.425
2019 Fanning S, Laine M, Greene M, Chang Y, Phung L, Green B, Hiipakka R, Han R, Komm B, Greene G. SUN-006 Lasofoxifene Achieves Potent Anti-Tumor Activity in Hormone-Resistant Breast Tumors by Maintaining High Affinity Binding for Y537S ERα Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-006  0.367
2019 Laine M, Fanning SW, Greene M, Chang Y, Phung L, Tan TT, Hiipakka R, Komm B, Greene G. Lasofoxifene as a potential treatment for ER+ metastatic breast cancer. Journal of Clinical Oncology. 37: 1056-1056. DOI: 10.1200/Jco.2019.37.15_Suppl.1056  0.389
2019 Laine M, Greene M, Chang Y, Phung L, Hiipakka R, Komm B, Greene G. Abstract PD7-09: Lasofoxifene decreases breast cancer lung and liver metastasis in a mammary intraductal (MIND) xenograft model of mutant ERα+ breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd7-09  0.374
2019 Plourde P, Schwartzberg L, Greene G, Portman D, Komm B, Jenkins S, Liu P, Portman, Goetz M. Abstract OT1-01-02: An open-label, randomized, multi-center phase 2 study evaluating the activity of lasofoxifene relative to fulvestrant for the treatment of postmenopausal women with locally advanced or metastatic ER+/HER2 - breast cancer (MBC) with an ESR1 mutation Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ot1-01-02  0.382
2019 Bueter E, Hosfield D, McAuley E, Selman P, Greene G, Conzen SD, Szmulewitz RZ. Abstract 1016: The androgen receptor splice variant AR-V7 associates with the glucocorticoid receptor following androgen blockade Cancer Research. 79: 1016-1016. DOI: 10.1158/1538-7445.Am2019-1016  0.412
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Greene GL, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/Elife.37161  0.718
2018 Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/Acschembio.8B00877  0.484
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 30185950 DOI: 10.1038/S41568-018-0053-0  0.335
2018 Fanning SW, Hodges-Gallagher L, Myles DC, Sun R, Fowler CE, Plant IN, Green BD, Harmon CL, Greene GL, Kushner PJ. Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nature Communications. 9: 2368. PMID 29915250 DOI: 10.1038/S41467-018-04413-3  0.462
2018 Maximov PY, Abderrahman B, Fanning SW, Sengupta S, Fan P, Curpan RF, Quintana Rincon DM, Greenland JA, Rajan SS, Greene GL, Jordan VC. Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Molecular Pharmacology. PMID 29739819 DOI: 10.1124/Mol.117.111385  0.466
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 29662238 DOI: 10.1038/S41568-018-0001-Z  0.494
2018 West DC, Kocherginsky M, Tonsing-Carter EY, Dolcen DN, Hosfield DJ, Lastra RR, Sinnwell JP, Thompson KJ, Bowie KR, Harkless RV, Skor MN, Pierce CF, Styke SC, Kim CR, de Wet L, ... Greene GL, et al. Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29636357 DOI: 10.1158/1078-0432.Ccr-17-2793  0.457
2018 Singhal H, Greene ME, Zarnke AL, Laine M, Al Abosy R, Chang YF, Dembo AG, Schoenfelt K, Vadhi R, Qiu X, Rao P, Santhamma B, Nair HB, Nickisch KJ, Long HW, ... ... Greene GL, et al. Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling. Oncotarget. 9: 4282-4300. PMID 29435103 DOI: 10.18632/Oncotarget.21378  0.491
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Greene GL, et al. Author response: The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells Elife. DOI: 10.7554/Elife.37161.024  0.677
2018 Laine M, Greene M, Chang Y, Phung L, Hiipakka R, Komm B, Greene G. Lasofoxifene efficacy in a mammary intraductal (MIND) xenograft model of ERα+ breast cancer. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E13054  0.424
2018 Dembo AG, Aledort ES, Greene GL. Abstract 948: Preventing estrogen receptor alpha-positive breast cancer outgrowth with the use of hormone replacement therapy Cancer Research. 78: 948-948. DOI: 10.1158/1538-7445.Am2018-948  0.439
2018 Speltz TE, Danes JM, Fanning SW, Mayne CG, Tajkhorshid E, Greene GL, Frasor JM, Moore TW. Abstract 1810: Stapled peptide inhibitors of mutant estrogen receptor/coactivator interactions Cancer Research. 78: 1810-1810. DOI: 10.1158/1538-7445.Am2018-1810  0.475
2017 Walter K, Goodman ML, Singhal H, Hall J, Li T, Holloran S, Trinca G, Gibson K, Jin VX, Greene G, Hagan C. Interferon-Stimulated Genes are Transcriptionally Repressed by PR in Breast Cancer. Molecular Cancer Research : McR. PMID 28684637 DOI: 10.1158/1541-7786.Mcr-17-0180  0.432
2017 Dembo A, Aledort E, Greene G. Abstract P3-04-19: Inhibition of ER-positive breast cancer progression with duavee, a new form of hormone replacement therapy Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-04-19  0.433
2017 Abderrahman B, Fanning SW, Rincon DQ, Greene G, Maximov PY, Jordan VC. Abstract 5633: Unique modulation of estrogen-induced apoptosis with structural analogues of endoxifen in long-term estrogen-deprived (LTED) breast cancer cells Cancer Research. 77: 5633-5633. DOI: 10.1158/1538-7445.Am2017-5633  0.395
2016 Singhal H, Greene ME, Tarulli G, Zarnke AL, Bourgo RJ, Laine M, Chang YF, Ma S, Dembo AG, Raj GV, Hickey TE, Tilley WD, Greene GL. Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer. Science Advances. 2: e1501924. PMID 27386569 DOI: 10.1126/Sciadv.1501924  0.49
2016 Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, ... Greene GL, et al. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife. 5. PMID 26836308 DOI: 10.7554/Elife.12792  0.423
2016 West D, Hosfield D, Mayne C, Skor M, Styke S, Pierce C, Kocherginsky M, Hunt H, Fleming G, Szmulewitz R, Tajkhorshid E, Greene G, Conzen S. Abstract PD3-02: Second-generation selective glucocorticoid receptor modulators in triple-negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-Pd3-02  0.479
2016 Maximov P, Sengupta S, Fernandes D, Fan P, Curpan R, Rajan S, Greene G, Jordan V. Abstract P3-05-11: The evolution of the estrogen receptor (ER) complex conformation governs estrogen-induced apoptosis in antihormone-resistant breast cancer cells Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-05-11  0.458
2016 Fanning SW, Dharmarajan V, Mayne CG, Toy W, Carlson KE, Martin TA, Nowak J, Nwachukwu J, Hosfield DJ, Tajkhorshid E, Chandarlapaty S, Griffin P, Shen Y, Katzenellenbogen JA, Greene GL. Abstract 4854: Bazedoxifene inhibits ESR1 somatic mutants with improved potency compared to tamoxifene and raloxifene Cancer Research. 76: 4854-4854. DOI: 10.1158/1538-7445.Am2016-4854  0.446
2016 Moore TW, Speltz TE, Fanning SW, Mayne CG, Frasor J, Greene GL, Tajkhorshid E. Abstract 3104: Stapled peptide inhibitors of the estrogen receptor/steroid receptor coactivator interaction Cancer Research. 76: 3104-3104. DOI: 10.1158/1538-7445.Am2016-3104  0.456
2016 Dembo AG, Greene GL. Abstract 1802: ER-positive breast cancer prevention with the use of hormone replacement therapy Cancer Research. 76: 1802-1802. DOI: 10.1158/1538-7445.Am2016-1802  0.433
2016 Chang Y, Wang Y, Greene G. Abstract 1264: Targeting nuclear receptors and their coregulators in triple-negative breast cancer Cancer Research. 76: 1264-1264. DOI: 10.1158/1538-7445.Am2016-1264  0.45
2016 Speltz TE, Fanning SW, Mayne CG, Fowler C, Tajkhorshid E, Greene GL, Moore TW. Inside Cover: Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction (Angew. Chem. Int. Ed. 13/2016) Angewandte Chemie International Edition. 55: 4104-4104. DOI: 10.1002/Anie.201601641  0.325
2016 Speltz TE, Fanning SW, Mayne CG, Fowler C, Tajkhorshid E, Greene GL, Moore TW. Innentitelbild: Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction (Angew. Chem. 13/2016) Angewandte Chemie. 128: 4174-4174. DOI: 10.1002/Ange.201601641  0.327
2015 Singhal H, Greene G. Relationship of progestin receptor to estrogen receptor and the relevance of the progestin receptor in predicting survival in breast cancer. Journal of Clinical Oncology. 33. DOI: 10.1200/Jco.2015.33.15_Suppl.E11514  0.5
2015 Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07  0.465
2015 Dembo A, Greene G. Abstract 5044: Reducing breast cancer risk with hormone replacement therapy Cancer Research. 75: 5044-5044. DOI: 10.1158/1538-7445.Am2015-5044  0.406
2014 Abot A, Fontaine C, Buscato M, Solinhac R, Flouriot G, Fabre A, Drougard A, Rajan S, Laine M, Milon A, Muller I, Henrion D, Adlanmerini M, Valéra MC, Gompel A, ... ... Greene GL, et al. The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation. Embo Molecular Medicine. 6: 1328-46. PMID 25214462 DOI: 10.15252/Emmm.201404112  0.391
2014 Singhal H, Greene G. Abstract 5571: Genome-wide crosstalk of estrogen and progesterone signaling in breast cancer Cancer Research. 74: 5571-5571. DOI: 10.1158/1538-7445.Am2014-5571  0.465
2014 Fontaine C, Abot A, Solinhac R, Drougard A, Fabre A, Buscato M, Milon A, Rajan S, Laine M, Henrion D, Mestdagt M, Raymond-Letron I, Flouriot G, Knauf C, Katzenellenbogen BS, ... ... Greene GL, et al. 0218: The uterine and vascular actions of estetrol delineate an original distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation Archives of Cardiovascular Diseases Supplements. 6: 8. DOI: 10.1016/S1878-6480(14)71283-2  0.359
2013 Toy W, Shen Y, Won H, Green B, Sakr RA, Will M, Li Z, Gala K, Fanning S, King TA, Hudis C, Chen D, Taran T, Hortobagyi G, Greene G, et al. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nature Genetics. 45: 1439-45. PMID 24185512 DOI: 10.1038/Ng.2822  0.462
2013 O'Leary KA, Jallow F, Rugowski DE, Sullivan R, Sinkevicius KW, Greene GL, Schuler LA. Prolactin activates ERα in the absence of ligand in female mammary development and carcinogenesis in vivo. Endocrinology. 154: 4483-92. PMID 24064365 DOI: 10.1210/En.2013-1533  0.812
2013 Le TP, Sun M, Luo X, Kraus WL, Greene GL. Mapping ERβ Genomic Binding Sites Reveals Unique Genomic Features and Identifies EBF1 as an ERβ Interactor Plos One. 8. PMID 23951143 DOI: 10.1371/Journal.Pone.0071355  0.618
2013 Huang W, Greene GL, Ravikumar KM, Yang S. Cross-talk between the ligand- and DNA-binding domains of estrogen receptor Proteins: Structure, Function and Bioinformatics. 81: 1900-1909. PMID 23737157 DOI: 10.1002/Prot.24331  0.364
2013 Chapa J, Bourgo RJ, Greene GL, Kulkarni S, An G. Examining the Pathogenesis of Breast Cancer Using a Novel Agent-Based Model of Mammary Ductal Epithelium Dynamics Plos One. 8. PMID 23704974 DOI: 10.1371/Journal.Pone.0064091  0.397
2013 Balbas MD, Evans MJ, Hosfield DJ, Wongvipat J, Arora VK, Watson PA, Chen Y, Greene GL, Shen Y, Sawyers CL. Overcoming mutation-based resistance to antiandrogens with rational drug design. Elife. 2: e00499. PMID 23580326 DOI: 10.7554/Elife.00499  0.304
2013 Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, Chang YF, Huo D, Wen Y, Swanson KE, Qiu T, Lu J, Young Park S, Eileen Dolan M, Perou CM, ... ... Greene GL, et al. MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 Nature Communications. 4. PMID 23340433 DOI: 10.1038/Ncomms2393  0.72
2013 Bockhorn J, Yee K, Chang YF, Prat A, Huo D, Nwachukwu C, Dalton R, Huang S, Swanson KE, Perou CM, Olopade OI, Clarke MF, Greene GL, Liu H. MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion Breast Cancer Research and Treatment. 137: 373-382. PMID 23224145 DOI: 10.1007/S10549-012-2346-4  0.717
2013 Greene GL. In Memoriam: Elwood Jensen (1920–2012) Molecular Endocrinology. 27: 1589-1591. DOI: 10.1210/Me.2013-1248  0.432
2013 Liu H, Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, Chang Y, Huo D, Lu J, Dolan E, Perou CM, Olopade OI, Clarke MF, Greene G. Abstract 832: MicroRNA-30c inhibits human breast tumor chemo-resistance by regulating twinfinlin-1 (TWF1) and IL-11. Cancer Research. 73: 832-832. DOI: 10.1158/1538-7445.Am2013-832  0.711
2013 Bockhorn J, Yee K, Chang Y, Prat A, Huo D, Nwachukwu C, Dalton R, Huang S, Swanson KE, Perou CM, Olufunmilayo OI, Clarke MF, Liu H, Greene G. Abstract 5337: MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. Cancer Research. 73: 5337-5337. DOI: 10.1158/1538-7445.Am2013-5337  0.719
2012 Romero IL, Lee W, Mitra AK, Gordon IO, Zhao Y, Leonhardt P, Penicka CV, Mui KL, Krausz TN, Greene GL, Lengyel E. The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis Gynecologic Oncology. 124: 134-141. PMID 21996264 DOI: 10.1016/J.Ygyno.2011.08.026  0.41
2012 Bourgo RJ, Greene GL. Abstract 804: The impact of aromatase inhibitor therapy on ER co-regulator expression and interaction Cancer Research. 72: 804-804. DOI: 10.1158/1538-7445.Am2012-804  0.427
2012 Pitch MA, Russell BA, Greene GL. Abstract 67: Characterization of the role of KLF9 transcription factor in breast cancer estrogen response Cancer Research. 72: 67-67. DOI: 10.1158/1538-7445.Am2012-67  0.399
2012 Huang S, Yee K, Bockhorn J, Kim S, Huo D, Olopade O, Liu H, Greene G. Abstract 4198: Transcriptional regulation of breast cancer microRNAs by GATA3 and TFAP2A Cancer Research. 72: 4198-4198. DOI: 10.1158/1538-7445.Am2012-4198  0.708
2012 Liu H, Bockhorn J, Dalton R, Nwachukwu C, Prat A, Yee K, Huang S, Swanson K, Perou CM, Olopade OI, Clarke MF, Greene GL. Abstract 3331: MicroRNAs regulate breast cancer stem cells and spontaneous metastases in orthotopic xenograft models Cancer Research. 72: 3331-3331. DOI: 10.1158/1538-7445.Am2012-3331  0.705
2011 Liu H, Bockhorn J, Dalton R, Dolan ME, Perou CM, Olopade OI, Clarke MF, Greene G. Roles of miRNAs in breast cancer stem cells, drug sensitivity, and spontaneous metastases in orthotopic human-in-mouse models. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1082. PMID 28021259 DOI: 10.1200/Jco.2011.29.15_Suppl.1082  0.345
2011 Liu H, Bockhorn J, Dalton R, Chang YF, Qian D, Zitzow LA, Clarke MF, Greene GL. Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting Journal of Virological Methods. 173: 266-270. PMID 21354210 DOI: 10.1016/J.Jviromet.2011.02.015  0.681
2011 Walker MP, Zhang M, Le TP, Wu P, Lainé M, Greene GL. RAC3 is a pro-migratory co-activator of ERα. Oncogene. 30: 1984-94. PMID 21217774 DOI: 10.1038/Onc.2010.583  0.654
2011 Liu H, Bockhorn J, Dalton R, Olopade OF, Clarke MF, Greene GL. Abstract 1582: Identification of miRNAs that regulate breast cancer stem cells and spontaneous metastases in orthotopic mouse models Cancer Research. 71: 1582-1582. DOI: 10.1158/1538-7445.Am2011-1582  0.704
2011 Bockhorn J, Chang Y, Liu H, Greene G. Abstract 1431: An optimized in vitro method to evaluate primary tumor cell invasion using optical imaging technology Cancer Research. 71: 1431-1431. DOI: 10.1158/1538-7445.Am2011-1431  0.654
2010 Romero IL, Lee W, Mui K, Leonhardt P, Penicka C, Greene GL, Lengyel E. Abstract A103: The effect of 17β-estradiol on ovarian carcinogenesis in vitro and in a genetic mouse model Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A103  0.394
2009 Sinkevicius KW, Woloszyn K, Laine M, Jackson KS, Greene GL, Woodruff TK, Burdette JE. Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor α knock-in (ENERKI) mice Steroids. 74: 913-919. PMID 19631674 DOI: 10.1016/J.Steroids.2009.06.012  0.797
2009 Sinkevicius KW, Laine M, Lotan TL, Woloszyn K, Richburg JH, Greene GL. Estrogen-dependent and -independent estrogen receptor-α signaling separately regulate male fertility Endocrinology. 150: 2898-2905. PMID 19264877 DOI: 10.1210/En.2008-1016  0.799
2009 Haiman CA, Garcia RR, Hsu C, Xia L, Ha H, Sheng X, Le Marchand L, Kolonel LN, Henderson BE, Stallcup MR, Greene GL, Press MF. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: The Multiethnic Cohort Bmc Cancer. 9. PMID 19183483 DOI: 10.1186/1471-2407-9-43  0.398
2009 Leong H, Mathur PS, Greene GL. Green tea catechins inhibit angiogenesis through suppression of STAT3 activation Breast Cancer Research and Treatment. 117: 505-515. PMID 18821062 DOI: 10.1007/S10549-008-0196-X  0.313
2008 O'Neill EE, Blewett AR, Loria PM, Greene GL. Modulation of alphaCaMKII signaling by rapid ERalpha action. Brain Research. 1222: 1-17. PMID 18572149 DOI: 10.1016/J.Brainres.2008.05.036  0.67
2008 Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses. Nature Chemical Biology. 4: 241-7. PMID 18344977 DOI: 10.1038/Nchembio.76  0.708
2008 Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo. Endocrinology. 149: 2970-9. PMID 18339713 DOI: 10.1210/En.2007-1526  0.798
2008 Hsieh RW, Rajan SS, Sharma SK, Greene GL. Molecular characterization of a B-ring unsaturated estrogen: Implications for conjugated equine estrogen components of Premarin Steroids. 73: 59-68. PMID 17949766 DOI: 10.1016/J.Steroids.2007.08.014  0.801
2008 Nettles KW, Gil G, Nowak J, Métivier R, Sharma VB, Greene GL. CBP is a dosage-dependent regulator of nuclear factor-κB suppression by the estrogen receptor Molecular Endocrinology. 22: 263-272. PMID 17932106 DOI: 10.1210/Me.2007-0324  0.692
2008 Leong H, Mathur PS, Greene GL. Inhibition of mammary tumorigenesis in the C3(1)/SV40 mouse model by green tea Breast Cancer Research and Treatment. 107: 359-369. PMID 17484049 DOI: 10.1007/S10549-007-9568-X  0.337
2008 Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachimiak A, Greene GL. Corrigendum: NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses (Nature Chemical Biology (2008) 4, (241-247)) Nature Chemical Biology. 4: 379. DOI: 10.1038/Nchembio0608-379B  0.704
2007 Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA. Elemental Isomerism: A Boron-Nitrogen Surrogate for a Carbon-Carbon Double Bond Increases the Chemical Diversity of Estrogen Receptor Ligands Chemistry and Biology. 14: 659-669. PMID 17584613 DOI: 10.1016/J.Chembiol.2007.04.009  0.684
2007 Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Hughs A, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL. Structural plasticity in the oestrogen receptor ligand-binding domain Embo Reports. 8: 563-568. PMID 17468738 DOI: 10.1038/Sj.Embor.7400963  0.787
2007 Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, Sharma S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA. Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. Journal of Medicinal Chemistry. 50: 399-403. PMID 17228884 DOI: 10.1021/Jm061035Y  0.709
2006 Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL. Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity Journal of Biological Chemistry. 281: 17909-17919. PMID 16648639 DOI: 10.1074/Jbc.M513684200  0.81
2006 Huang J, Koide A, Nettle KW, Greene GL, Koide S. Conformation-specific affinity purification of proteins using engineered binding proteins: Application to the estrogen receptor Protein Expression and Purification. 47: 348-354. PMID 16325424 DOI: 10.1016/J.Pep.2005.10.021  0.348
2005 Yeo WS, Min DH, Hsieh RW, Greene GL, Mrksich M. Label-free detection of protein-protein interactions on biochips Angewandte Chemie - International Edition. 44: 5480-5483. PMID 16052641 DOI: 10.1002/Anie.200501363  0.757
2005 Leong H, Sloan JR, Nash PD, Greene GL. Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor α Molecular Endocrinology. 19: 2930-2942. PMID 16051668 DOI: 10.1210/Me.2005-0178  0.395
2005 Wu YL, Yang X, Ren Z, McDonnell DP, Norris JD, Willson TM, Greene GL. Structural basis for an unexpected mode of SERM-Mediated ER antagonism Molecular Cell. 18: 413-424. PMID 15893725 DOI: 10.1016/J.Molcel.2005.04.014  0.572
2005 Nettles KW, Greene GL. Ligand control of coregulator recruitment to nuclear receptors Annual Review of Physiology. 67: 309-333. PMID 15709961 DOI: 10.1146/Annurev.Physiol.66.032802.154710  0.694
2004 Greene GL, Shiau AK, Nettles KW. A structural explanation for ERalpha/ERbeta SERM discrimination. Ernst Schering Research Foundation Workshop. 33-45. PMID 15248503 DOI: 10.1007/978-3-662-05386-7_3  0.657
2004 Razandi M, Pedram A, Merchenthaler I, Greene GL, Levin ER. Plasma membrane estrogen receptors exist and functions as dimers Molecular Endocrinology. 18: 2854-2865. PMID 15231873 DOI: 10.1210/Me.2004-0115  0.4
2004 Nettles KW, Sun J, Radek JT, Sheng S, Rodriguez AL, Katzenellenbogen JA, Katzenellenbogen BS, Greene GL. Allosteric Control of Ligand Selectivity between Estrogen Receptors α and β: Implications for Other Nuclear Receptors Molecular Cell. 13: 317-327. PMID 14967140 DOI: 10.1016/S1097-2765(04)00054-1  0.708
2003 Nettles KW, Greene GL. Nuclear receptor ligands and cofactor recruitment: Is there a coactivator "On Deck"? Molecular Cell. 11: 850-851. PMID 12718871 DOI: 10.1016/S1097-2765(03)00133-3  0.687
2003 Greene GL. In vivo imaging reveals estrogen receptor's hidden personality Nature Medicine. 9: 22-23. PMID 12514716 DOI: 10.1038/Nm0103-22  0.42
2002 Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nature Structural Biology. 9: 359-64. PMID 11953755 DOI: 10.1038/Nsb787  0.69
2001 Griffin C, Flouriot G, Sharp P, Greene G, Gannon F. Distribution Analysis of the Two Chicken Estrogen Receptor-Alpha Isoforms and Their Transcripts in the Hypothalamus and Anterior Pituitary Gland Biology of Reproduction. 65: 1156-1163. PMID 11566738 DOI: 10.1095/Biolreprod65.4.1156  0.376
2000 Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM, Webb P. Estrogen receptor pathways to AP-1. The Journal of Steroid Biochemistry and Molecular Biology. 74: 311-7. PMID 11162939 DOI: 10.1016/S0960-0760(00)00108-4  0.443
2000 Kushner PJ, Agard D, Feng WJ, Lopez G, Schiau A, Uht R, Webb P, Greene G. Oestrogen receptor function at classical and alternative response elements Novartis Foundation Symposium. 230: 20-32. PMID 10965500 DOI: 10.1002/0470870818.Ch3  0.407
1999 Li G, Chen YF, Greene GL, Oparil S, Thompson JA. Estrogen inhibits vascular smooth muscle cell-dependent adventitial fibroblast migration in vitro Circulation. 100: 1639-1645. PMID 10517736 DOI: 10.1161/01.Cir.100.15.1639  0.342
1999 Lopez GN, Webb P, Shinsako JH, Baxter JD, Greene GL, Kushner PJ. Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators Molecular Endocrinology. 13: 897-909. PMID 10379889 DOI: 10.1210/Mend.13.6.0283  0.466
1999 Razandi M, Pedram A, Greene GL, Levin ER. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERα and ERβ expressed in chinese hamster ovary cells Molecular Endocrinology. 13: 307-319. PMID 9973260 DOI: 10.1210/Mend.13.2.0239  0.415
1999 Pertschuk LP, Money SR, Baliga P, Greene GL. Estrogen receptor immunoreactivity in the human and macaque cardiovascular systems Applied Immunohistochemistry. 7: 9-13. DOI: 10.1097/00022744-199903000-00005  0.355
1998 Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell. 95: 927-37. PMID 9875847 DOI: 10.1016/S0092-8674(00)81717-1  0.395
1998 Wood JR, Greene GL, Nardulli AM. Estrogen response elements function as allosteric modulators of estrogen receptor conformation. Molecular and Cellular Biology. 18: 1927-34. PMID 9528764 DOI: 10.1128/Mcb.18.4.1927  0.428
1997 Greene ME, Blumberg B, Kwan K, Hsieh L, Greene GL, Nimer SD. Isolation and cloning of human peroxisome proliferator activated receptor gamma cDNA. Advances in Experimental Medicine and Biology. 400: 253-60. PMID 9547566 DOI: 10.1007/978-1-4615-5325-0_37  0.421
1997 Landel CC, Potthoff SJ, Nardulli AM, Kushner PJ, Greene GL. Estrogen receptor accessory proteins augment receptor-DNA interaction and DNA bending. The Journal of Steroid Biochemistry and Molecular Biology. 63: 59-73. PMID 9449207 DOI: 10.1016/S0960-0760(97)00073-3  0.386
1997 Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engström O, Ohman L, Greene GL, Gustafsson JA, Carlquist M. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature. 389: 753-8. PMID 9338790 DOI: 10.1038/39645  0.455
1997 Hess RA, Gist DH, Bunick D, Lubahn DB, Farrell A, Bahr J, Cooke PS, Greene GL. Estrogen Receptor (α and β) Expression in the Excurrent Ducts of the Adult Male Rat Reproductive Tract Journal of Andrology. 18: 602-611. DOI: 10.1002/J.1939-4640.1997.Tb02437.X  0.396
1996 Desombre ER, Hughes A, Landel CC, Greene G, Hanson R, Schwartz JL. Cellular And Subcellular Studies Of The Radiation Effects Of Auger Electron-Emitting Estrogens Acta Oncologica. 35: 833-840. PMID 9004760 DOI: 10.3109/02841869609104034  0.364
1996 Pertschuk LP, Masood S, Simone J, Feldman JG, Fruchter RG, Axiotis CA, Greene GL. Estrogen receptor immunocytochemistry in endometrial carcinoma: a prognostic marker for survival. Gynecologic Oncology. 63: 28-33. PMID 8898164 DOI: 10.1006/Gyno.1996.0273  0.382
1996 Kim-Schulze S, McGowan KA, Hubchak SC, Cid MC, Martin MB, Kleinman HK, Greene GL, Schnaper HW. Expression of an estrogen receptor by human coronary artery and umbilical vein endothelial cells. Circulation. 94: 1402-7. PMID 8822999 DOI: 10.1161/01.Cir.94.6.1402  0.353
1996 Nardulli AM, Romine LE, Carpo C, Greene GL, Rainish B. Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters. Molecular Endocrinology (Baltimore, Md.). 10: 694-704. PMID 8776729 DOI: 10.1210/Mend.10.6.8776729  0.401
1995 Landel CC, Kushner PJ, Greene GL. Estrogen receptor accessory proteins: effects on receptor-DNA interactions. Environmental Health Perspectives. 103: 23-8. PMID 8593869 DOI: 10.1289/Ehp.95103S723  0.398
1995 Seielstad DA, Carlson KE, Katzenellenbogen JA, Kushner PJ, Greene GL. Molecular characterization by mass spectrometry of the human estrogen receptor ligand-binding domain expressed in Escherichia coli. Molecular Endocrinology (Baltimore, Md.). 9: 647-58. PMID 8592511 DOI: 10.1210/Mend.9.6.8592511  0.353
1995 Nyholm HC, Nielsen AL, Lyndrup J, Greene GL, Thorpe SM. Estrogen receptor determination in endometrial carcinoma: ligand binding assay versus enzyme immunoassay. Anticancer Research. 15: 649-54. PMID 7763051  0.315
1995 Seielstad DA, Carlson KE, Kushner PJ, Greene GL, Katzenellenbogen JA. Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis. Biochemistry. 34: 12605-15. PMID 7548010 DOI: 10.1021/Bi00039A016  0.372
1994 Landel CC, Kushner PJ, Greene GL. The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins. Molecular Endocrinology (Baltimore, Md.). 8: 1407-19. PMID 7854357 DOI: 10.1210/Mend.8.10.7854357  0.377
1994 Pertschuk LP, Macchia RJ, Feldman JG, Brady KA, Levine M, Kim DS, Eisenberg KB, Rainford E, Prins GS, Greene GL. Immunocytochemical assay for androgen receptors in prostate cancer: a prospective study of 63 cases with long-term follow-up. Annals of Surgical Oncology. 1: 495-503. PMID 7531602 DOI: 10.1007/Bf02303615  0.326
1993 Miller RT, Hapke MR, Greene GL. Immunocytochemical assay for estrogen receptor with monoclonal antibody D753P gamma in routinely processed formaldehyde-fixed breast tissue. Comparison with frozen section assay and with monoclonal antibody H222. Cancer. 71: 3541-6. PMID 8490902 DOI: 10.1002/1097-0142(19930601)71:11<3541::Aid-Cncr2820711113>3.0.Co;2-X  0.33
1993 Nardulli AM, Greene GL, Shapiro DJ. Human estrogen receptor bound to an estrogen response element bends DNA. Molecular Endocrinology (Baltimore, Md.). 7: 331-40. PMID 8483477 DOI: 10.1210/Mend.7.3.8483477  0.392
1993 Tucker MS, Khan I, Fuchs-Young R, Price S, Steininger TL, Greene G, Wainer BH, Rosner MR. Localization of immunoreactive epidermal growth factor receptor in neonatal and adult rat hippocampus. Brain Research. 631: 65-71. PMID 8298997 DOI: 10.1016/0006-8993(93)91187-W  0.337
1993 Fuqua SA, Allred DC, Elledge RM, Krieg SL, Benedix MG, Nawaz Z, O'Malley BW, Greene GL, McGuire WL. The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain. Breast Cancer Research and Treatment. 26: 191-202. PMID 8219256 DOI: 10.1007/Bf00689692  0.451
1992 Fuqua SA, Fitzgerald SD, Allred DC, Elledge RM, Nawaz Z, McDonnell DP, O'Malley BW, Greene GL, McGuire WL. Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Research. 52: 483-6. PMID 1728420  0.373
1992 Webb P, Lopez GN, Greene GL, Baxter JD, Kushner PJ. The limits of the cellular capacity to mediate an estrogen response. Molecular Endocrinology (Baltimore, Md.). 6: 157-67. PMID 1569962 DOI: 10.1210/Mend.6.2.1569962  0.428
1992 Jung-Testas I, Renoir M, Bugnard H, Greene GL, Baulieu EE. Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells. The Journal of Steroid Biochemistry and Molecular Biology. 41: 621-31. PMID 1562533 DOI: 10.1016/0960-0760(92)90394-X  0.419
1992 Wang JD, Fu Y, Shi WL, Zhu PD, Cheng J, Qiao GM, Wang YQ, Greene GL. Immunohistochemical localization of progesterone receptor in human decidua of early pregnancy. Human Reproduction (Oxford, England). 7: 123-7. PMID 1551948 DOI: 10.1093/Oxfordjournals.Humrep.A137545  0.346
1992 Bettuzzi S, Robinson A, Fuchs-Young R, Greene GL. Estrogen and progesterone receptor structure and action in breast cancer cells. Cancer Treatment and Research. 61: 301-15. PMID 1360239 DOI: 10.1007/978-1-4615-3500-3_15  0.499
1992 Beckmann MW, Toney LJ, Scharl A, Fuchs-Young R, Greene GL, Holt JA. Detection of the HER-2/neu proto-oncogene protein p185erbB2 by a novel monoclonal antibody (MAB-145ww) in breast cancer membranes from oestrogen and progesterone receptor assays. European Journal of Cancer (Oxford, England : 1990). 28: 322-6. PMID 1350453 DOI: 10.1016/S0959-8049(05)80046-2  0.411
1991 Tóth J, De Sombre ER, Greene GL. Immunohistochemical analysis of estrogen and progesterone receptors in benign breast diseases. Zentralblatt FüR Pathologie. 137: 227-32. PMID 1931896  0.315
1991 Berger U, McClelland RA, Wilson P, Greene GL, Haussler MR, Pike JW, Colston K, Easton D, Coombes RC. Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis. Cancer Research. 51: 239-44. PMID 1846309  0.319
1991 Ozzello L, DeRosa C, Habif DV, Greene GL. An immunohistochemical evaluation of progesterone receptor in frozen sections, paraffin sections, and cytologic imprints of breast carcinomas. Cancer. 67: 455-62. PMID 1845948 DOI: 10.1002/1097-0142(19910115)67:2<455::Aid-Cncr2820670223>3.0.Co;2-M  0.375
1991 Fuqua SA, Hill SM, Chamness GC, Benedix MG, Greene GL, O'Malley BW, McGuire WL. Progesterone receptor gene restriction fragment length polymorphisms in human breast tumors. Journal of the National Cancer Institute. 83: 1157-60. PMID 1679459 DOI: 10.1093/Jnci/83.16.1157  0.373
1990 Pertschuk LP, Kim DS, Nayer K, Feldman JG, Eisenberg KB, Carter AC, Rong ZT, Thelmo WL, Fleisher J, Greene GL. Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival. Cancer. 66: 1663-70. PMID 2208020 DOI: 10.1002/1097-0142(19901015)66:8<1663::Aid-Cncr2820660802>3.0.Co;2-C  0.408
1990 Kushner PJ, Hort E, Shine J, Baxter JD, Greene GL. Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens. Molecular Endocrinology (Baltimore, Md.). 4: 1465-73. PMID 2178215 DOI: 10.1210/Mend-4-10-1465  0.433
1989 Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai MJ, O'Malley BW. Specific binding of estrogen receptor to the estrogen response element. Molecular and Cellular Biology. 9: 43-9. PMID 2927397 DOI: 10.1128/Mcb.9.1.43  0.458
1989 Read LD, Greene GL, Katzenellenbogen BS. Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and growth factors. Molecular Endocrinology (Baltimore, Md.). 3: 295-304. PMID 2785242 DOI: 10.1210/Mend-3-2-295  0.403
1989 Berger U, Wilson P, Thethi S, McClelland RA, Greene GL, Coombes RC. Comparison of an immunocytochemical assay for progesterone receptor with a biochemical method of measurement and immunocytochemical examination of the relationship between progesterone and estrogen receptors. Cancer Research. 49: 5176-9. PMID 2766287  0.351
1989 Press MF, Xu SH, Wang JD, Greene GL. Subcellular distribution of estrogen receptor and progesterone receptor with and without specific ligand. The American Journal of Pathology. 135: 857-64. PMID 2683797  0.335
1989 Kinsel LB, Szabo E, Greene GL, Konrath J, Leight GS, McCarty KS. Immunocytochemical analysis of estrogen receptors as a predictor of prognosis in breast cancer patients: comparison with quantitative biochemical methods. Cancer Research. 49: 1052-6. PMID 2643460  0.331
1989 Hill SM, Fuqua SA, Chamness GC, Greene GL, McGuire WL. Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism. Cancer Research. 49: 145-8. PMID 2562795  0.331
1989 DeRosa CM, Ozzello L, Habif DV, Konrath JG, Greene GL. Immunohistochemical assessment of estrogen and progesterone receptors in stored imprints and cryostat sections of breast carcinomas. Annals of Surgery. 210: 224-8. PMID 2547346 DOI: 10.1097/00000658-198908000-00015  0.443
1988 Read LD, Snider CE, Miller JS, Greene GL, Katzenellenbogen BS. Ligand-modulated regulation of progesterone receptor messenger ribonucleic acid and protein in human breast cancer cell lines. Molecular Endocrinology (Baltimore, Md.). 2: 263-71. PMID 3398853 DOI: 10.1210/Mend-2-3-263  0.412
1988 Waterman ML, Adler S, Nelson C, Greene GL, Evans RM, Rosenfeld MG. A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene. Molecular Endocrinology (Baltimore, Md.). 2: 14-21. PMID 3398840 DOI: 10.1210/Mend-2-1-14  0.405
1988 Nardulli AM, Greene GL, O'Malley BW, Katzenellenbogen BS. Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation. Endocrinology. 122: 935-44. PMID 3342760 DOI: 10.1210/Endo-122-3-935  0.415
1988 Press MF, Greene GL. Localization of progesterone receptor with monoclonal antibodies to the human progestin receptor. Endocrinology. 122: 1165-75. PMID 3342750 DOI: 10.1210/Endo-122-3-1165  0.424
1988 Pertschuk LP, Feldman JG, Eisenberg KB, Carter AC, Thelmo WL, Cruz WP, Thorpe SM, Christensen J, Rasmussen BB, Rose C, Greene GL. Immunocytochemical detection of progesterone receptor in breast cancer with monoclonal antibody. Relation to biochemical assay, disease-free survival, and clinical endocrine response Cancer. 62: 342-349. PMID 3289729 DOI: 10.1002/1097-0142(19880715)62:2<342::Aid-Cncr2820620219>3.0.Co;2-1  0.361
1988 West NB, Roselli CE, Resko JA, Greene GL, Brenner RM. Estrogen and progestin receptors and aromatase activity in rhesus monkey prostate. Endocrinology. 123: 2312-22. PMID 3262505 DOI: 10.1210/Endo-123-5-2312  0.377
1988 Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, Korc M, Greene GL, O'Malley BW, Haussler MR. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science (New York, N.Y.). 241: 81-4. PMID 3164526 DOI: 10.1126/Science.3164526  0.425
1988 Greene GL, Harris K, Bova R, Kinders R, Moore B, Nolan C. Purification of T47D human progesterone receptor and immunochemical characterization with monoclonal antibodies. Molecular Endocrinology (Baltimore, Md.). 2: 714-26. PMID 2463480 DOI: 10.1210/Mend-2-8-714  0.373
1988 Lessey BA, Killam AP, Metzger DA, Haney AF, Greene GL, McCarty KS. Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. The Journal of Clinical Endocrinology and Metabolism. 67: 334-40. PMID 2455728 DOI: 10.1210/Jcem-67-2-334  0.418
1987 Denner LA, Bingman WE, Greene GL, Weigel NL. Phosphorylation of the chicken progesterone receptor. Journal of Steroid Biochemistry. 27: 235-43. PMID 3695483 DOI: 10.1016/0022-4731(87)90315-3  0.355
1987 Alexander RB, Greene GL, Barrack ER. Estrogen receptors in the nuclear matrix: direct demonstration using monoclonal antireceptor antibody. Endocrinology. 120: 1851-7. PMID 3569116 DOI: 10.1210/Endo-120-5-1851  0.403
1987 Rao KV, Peralta WD, Greene GL, Fox CF. Cellular progesterone receptor phosphorylation in response to ligands activating protein kinases. Biochemical and Biophysical Research Communications. 146: 1357-65. PMID 3497636 DOI: 10.1016/0006-291X(87)90799-6  0.395
1987 Law ML, Kao FT, Wei Q, Hartz JA, Greene GL, Zarucki-Schulz T, Conneely OM, Jones C, Puck TT, O'Malley BW. The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2. Proceedings of the National Academy of Sciences of the United States of America. 84: 2877-81. PMID 3472240 DOI: 10.1073/Pnas.84.9.2877  0.364
1987 Bur ME, Greene GL, Press MF. Estrogen receptor localization in formalin-fixed, paraffin-embedded endometrium and endometriotic tissues. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 6: 140-51. PMID 3319920 DOI: 10.1097/00004347-198706000-00006  0.348
1987 Jensen EV, Greene GL, DeSombre ER. Immunochemical studies of estrogen receptors. Progress in Clinical and Biological Research. 249: 283-305. PMID 3313429  0.343
1987 Maxwell BL, McDonnell DP, Conneely OM, Schulz TZ, Greene GL, O'Malley BW. Structural organization and regulation of the chicken estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 1: 25-35. PMID 2901032 DOI: 10.1210/Mend-1-1-25  0.372
1987 De Rosa CM, Ozzello L, Greene GL, Habif DV. Immunostaining of estrogen receptor in paraffin sections of breast carcinomas using monoclonal antibody D75P3 gamma: effects of fixation. The American Journal of Surgical Pathology. 11: 943-50. PMID 2825550 DOI: 10.1097/00000478-198712000-00004  0.394
1986 Greene GL, Gilna P, Waterfield M, Baker A, Hort Y, Shine J. Sequence and expression of human estrogen receptor complementary DNA. Science (New York, N.Y.). 231: 1150-4. PMID 3753802 DOI: 10.1126/Science.3753802  0.448
1986 Greene GL, Press MF. Structure and dynamics of the estrogen receptor Journal of Steroid Biochemistry. 24: 1-7. PMID 3517497 DOI: 10.1016/0022-4731(86)90024-5  0.495
1986 Raymoure WJ, McNaught RW, Greene GL, Smith RG. Receptor interconversion model of hormone action. II. Nucleotide-mediated conversion of estrogen receptors from nonsteroid binding to the lower affinity binding state. The Journal of Biological Chemistry. 261: 17018-25. PMID 3023379  0.318
1986 Press MF, Nousek-Goebl NA, Bur M, Greene GL. Estrogen receptor localization in the female genital tract. The American Journal of Pathology. 123: 280-92. PMID 2939725 DOI: 10.1097/00006254-198703000-00015  0.389
1986 Conneely OM, Sullivan WP, Toft DO, Birnbaumer M, Cook RG, Maxwell BL, Zarucki-Schulz T, Greene GL, Schrader WT, O'Malley BW. Molecular cloning of the chicken progesterone receptor. Science (New York, N.Y.). 233: 767-70. PMID 2426779 DOI: 10.1126/Science.2426779  0.378
1986 Green S, Walter P, Greene G, Krust A, Goffin C, Jensen E, Scrace G, Waterfield M, Chambon P. Cloning of the human oestrogen receptor cDNA Journal of Steroid Biochemistry. 24: 77-83. PMID 2422449 DOI: 10.1016/0022-4731(86)90035-X  0.366
1985 Bronzert DA, Greene GL, Lippman ME. Selection and Characterization of a Breast Cancer Cell Line Resistant to the Antiestrogen LY 117018 Endocrinology. 117: 1409-1417. PMID 4029083 DOI: 10.1210/Endo-117-4-1409  0.414
1985 Press MF, Nousek-Goebl NA, Greene GL. Immunoelectron microscopic localization of estrogen receptor with monoclonal estrophilin antibodies. Journal of Histochemistry and Cytochemistry. 33: 915-924. PMID 4020102 DOI: 10.1177/33.9.4020102  0.429
1985 Lorincz MA, Holt JA, Greene GL. Monoclonal antibody recognition of multiple forms of estrogen receptor tagged with [125I]methoxy-iodovinyl estradiol in ovarian carcinomas. The Journal of Clinical Endocrinology and Metabolism. 61: 412-7. PMID 4019711 DOI: 10.1210/Jcem-61-3-412  0.451
1985 Miller MA, Mullick A, Greene GL, Katzenellenbogen BS. Characterization of the subunit nature of nuclear estrogen receptors by chemical cross-linking and dense amino acid labeling Endocrinology. 117: 515-522. PMID 4017945 DOI: 10.1210/Endo-117-2-515  0.397
1985 Walter P, Green S, Greene G, Krust A, Bornert JM, Jeltsch JM, Staub A, Jensen E, Scrace G, Waterfield M. Cloning of the human estrogen receptor cDNA Proceedings of the National Academy of Sciences of the United States of America. 82: 7889-7893. PMID 3865204 DOI: 10.1073/Pnas.82.23.7889  0.369
1985 Poulsen HS, Ozzello L, King WJ, Greene GL. The use of monoclonal antibodies to estrogen receptors (ER) for immunoperoxidase detection of ER in paraffin sections of human breast cancer tissue Journal of Histochemistry and Cytochemistry. 33: 87-92. PMID 2578501 DOI: 10.1177/33.2.2578501  0.449
1985 Press MF, Nousek-Goebl N, King WJ, Herbst AL, Greene GL. Immunohistochemical Assessment of Estrogen Receptor Distribution in the Human Endometrium throughout the Menstrual Cycle Obstetrical & Gynecological Survey. 40: 651-653. DOI: 10.1097/00006254-198510000-00017  0.358
1985 Greene GL, King WJ. Subcellular distribution of oestrogen receptors Nature. 317: 88-89. DOI: 10.1038/317088B0  0.332
1985 Holt JA, Lorincz MA, Greene GL, Herbst AL. Abstract selected for presentation at the Sixteenth Annual Meeting of the Society of Gynecologic Oncologists February 3–6, 1985Monoclonal antibodies demonstrate multiple forms of estrogen receptor in ovarian adenocarcinomas Gynecologic Oncology. 20: 270. DOI: 10.1016/0090-8258(85)90207-0  0.358
1985 Holt J, Gibson R, Hamilton T, Greene G, Herbst A. Estrogen receptor-rich ovarian adenocarcinoma in vitro and OVCAR-3 in vivo bind radio-halogenated moxestrol (R-2858) Gynecologic Oncology. 20: 255. DOI: 10.1016/0090-8258(85)90171-4  0.391
1984 Giambiagi N, Pasqualini JR, Greene G, Jensen EV. Recognition of two forms of the estrogen receptor in the guinea-pig uterus at different stages of development by a monoclonal antibody to the human estrogen receptor. Dynamics of the translocation of these two forms to the nucleus. Journal of Steroid Biochemistry. 20: 397-400. PMID 6708523 DOI: 10.1016/0022-4731(84)90241-3  0.398
1984 King WJ, Greene GL. Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells. Nature. 307: 745-747. PMID 6700704 DOI: 10.1038/307745A0  0.41
1984 Miller MA, Greene GL, Katzenellenbogen BS. Estrogen receptor transformation in MCF-7 breast cancer cells: Characterization by immunochemical and sedimentation analyses Endocrinology. 114: 296-298. PMID 6690275 DOI: 10.1210/Endo-114-1-296  0.395
1984 Kasid A, Strobl JS, Huff K, Greene GL, Lippman ME. A novel nuclear form of estradiol receptor in MCF-7 human breast cancer cells. Science (New York, N.Y.). 225: 1162-5. PMID 6474170 DOI: 10.1126/Science.6474170  0.466
1984 McClellan MC, West NB, Tacha DE, Greene GL, Brenner RM. Immunocytochemical localization of estrogen receptors in the macaque reproductive tract with monoclonal antiestrophilins. Endocrinology. 114: 2002-14. PMID 6373239 DOI: 10.1210/Endo-114-6-2002  0.379
1984 Greene GL, Sobel NB, King WJ, Jensen EV. Immunochemical studies of estrogen receptors. Journal of Steroid Biochemistry. 20: 51-6. PMID 6200700 DOI: 10.1016/0022-4731(84)90188-2  0.435
1984 Greene GL. CHAPTER 8 – Application of Immunochemical Techniques to the Analysis of Estrogen Receptor Structure and Function Biochemical Actions of Hormones. 207-239. DOI: 10.1016/B978-0-12-452811-6.50013-X  0.36
1983 Tate AC, DeSombre ER, Greene GL, Jensen EV, Jordan VC. Interaction of [3H] estradiol - and [3H] monohydroxytamoxifen-estrogen receptor complexes with a monoclonal antibody. Breast Cancer Research and Treatment. 3: 267-77. PMID 6671136 DOI: 10.1007/Bf01806700  0.42
1983 Ekman P, Barrack ER, Greene GL, Jensen EV, Walsh PC. Estrogen receptors in human prostate: evidence for multiple binding sites. The Journal of Clinical Endocrinology and Metabolism. 57: 166-76. PMID 6189851 DOI: 10.1210/Jcem-57-1-166  0.396
1983 Holt J, Makii M, Greene G, Herbst A, Tate A, Jordan V. Monoclonal antibody recognition of [3H]monohydroxytamoxifen-receptor and 125I-estradiol-receptor complex in ovarian epithelial carcinoma Gynecologic Oncology. 15: 134. DOI: 10.1016/0090-8258(83)90129-4  0.361
1982 Garcia M, Greene G, Rochefort H, Jensen EV. Effect of antibodies to estrogen receptor on the binding of 3H-labeled antiestrogens and androstanediol in the uterus. Endocrinology. 110: 1355-61. PMID 7060530 DOI: 10.1210/Endo-110-4-1355  0.413
1982 Greene GL, Jensen EV. Monoclonal antibodies as probes for estrogen receptor detection and characterization. Journal of Steroid Biochemistry. 16: 353-9. PMID 6979662 DOI: 10.1016/0022-4731(82)90045-0  0.422
1982 Jensen EV, Greene GL, Closs LE, DeSombre ER, Nadji M. Receptors reconsidered: a 20-year perspective. Recent Progress in Hormone Research. 38: 1-40. PMID 6289391 DOI: 10.1016/B978-0-12-571138-8.50006-8  0.451
1982 Kasid A, Strobl J, Greene G, Lippman M. 124. Receptor processing: Represents conversion to a new nuclear form of estradiol receptor (ER) Journal of Steroid Biochemistry. 17. DOI: 10.1016/0022-4731(82)90338-7  0.412
1980 Greene GL, Closs LE, De Sombre ER, Jensen EV. Estrophilin: pro and anti. Journal of Steroid Biochemistry. 12: 159-67. PMID 7421204 DOI: 10.1016/0022-4731(80)90265-4  0.354
1980 Greene GL, Nolan C, Engler JP, Jensen EV. Monoclonal antibodies to human estrogen receptor. Proceedings of the National Academy of Sciences of the United States of America. 77: 5115-9. PMID 7001472 DOI: 10.1073/Pnas.77.9.5115  0.441
1980 Greene GL, Fitch FW, Jensen EV. Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors. Proceedings of the National Academy of Sciences of the United States of America. 77: 157-61. PMID 6928610 DOI: 10.1073/Pnas.77.1.157  0.357
1979 Greene GL, Closs LE, DeSombre ER, Jensen EV. Antibodies to estrophilin: comparison between rabbit and goat antisera. Journal of Steroid Biochemistry. 11: 333-41. PMID 491602 DOI: 10.1016/0022-4731(79)90316-9  0.407
1979 Jensen EV, Greene GL, Closs LE, DeSombre ER. The immunoendocrinology of estrophilin. Advances in Experimental Medicine and Biology. 117: 1-16. PMID 474273 DOI: 10.1007/978-1-4757-6589-2_1  0.419
1977 Greene GL, Closs LE, Fleming H, DeSombre ER, Jensen EV. Antibodies to estrogen receptor: immunochemical similarity of estrophilin from various mammalian species. Proceedings of the National Academy of Sciences of the United States of America. 74: 3681-5. PMID 269423 DOI: 10.1073/Pnas.74.9.3681  0.421
1975 Greene GL, Letsinger RL. Formation of internucleotide 3'-5' phosphoramidate links by direct coupling of phosphoryl and amino groups. Nucleic Acids Research. 2: 1123-7. PMID 1153331 DOI: 10.1093/Nar/2.7.1123  0.484
1975 Mungall WS, Greene GL, Heavner GA, Letsinger RL. Use of azido group in the synthesis of 5' terminal aminodeoxythymidine oligonucleotides. The Journal of Organic Chemistry. 40: 1569-62. PMID 1142038 DOI: 10.1021/Jo00899A038  0.483
1975 Mungall WS, Greene GL, Heavner GA, Letsinger RL. Use of the azido group in the synthesis of 5′ terminal aminodeoxythymidine oligonucleotides Journal of Organic Chemistry. 40: 1659-1662. DOI: 10.1002/Chin.197536407  0.485
1974 Mungall WS, Greene GL, Miller PS, Letsinger RL. Use of phosphorus oxychloride in synthesizing nucleotides and oligonucleotides. Nucleic Acids Research. 1: 615-27. PMID 10793743 DOI: 10.1093/Nar/1.4.615  0.588
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