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Catherine M. Joyce - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Biochemistry
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61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Bermek O, Grindley ND, Joyce CM. Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766. Biochemistry. 52: 6258-74. PMID 23937394 DOI: 10.1021/Bi400837K  0.617
2013 Hohlbein J, Aigrain L, Craggs TD, Bermek O, Potapova O, Shoolizadeh P, Grindley ND, Joyce CM, Kapanidis AN. Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion. Nature Communications. 4: 2131. PMID 23831915 DOI: 10.1038/Ncomms3131  0.575
2011 Arana ME, Potapova O, Kunkel TA, Joyce CM. Kinetic analysis of the unique error signature of human DNA polymerase ν. Biochemistry. 50: 10126-35. PMID 22008035 DOI: 10.1021/Bi201197P  0.572
2011 Bermek O, Grindley ND, Joyce CM. Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions. The Journal of Biological Chemistry. 286: 3755-66. PMID 21084297 DOI: 10.1074/Jbc.M110.167593  0.535
2011 Hohlbein J, Joyce CM, Shoolizadeh P, Evans G, Potapova O, Bermek O, Duchillumigusin D, Grindley ND, Kapanidis AN. Novel Conformational States in Mutator DNA Polymerases Observed Using Single-Molecule FRET Biophysical Journal. 100: 240a-241a. DOI: 10.1016/J.Bpj.2010.12.1532  0.595
2010 Foti JJ, Delucia AM, Joyce CM, Walker GC. UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs. The Journal of Biological Chemistry. 285: 23086-95. PMID 20467052 DOI: 10.1074/Jbc.M110.115774  0.564
2010 Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN. Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Proceedings of the National Academy of Sciences of the United States of America. 107: 715-20. PMID 20080740 DOI: 10.1073/Pnas.0910909107  0.575
2010 Joyce CM. Techniques used to study the DNA polymerase reaction pathway Biochimica Et Biophysica Acta - Proteins and Proteomics. 1804: 1032-1040. PMID 19665596 DOI: 10.1016/J.Bbapap.2009.07.021  0.499
2010 Hohlbein J, Le Reste L, Potapova O, Joyce C, El-Sagheer AH, Brown T, Kapanidis AN. Towards Dark Quencher Based Real Time DNA Sequencing Biophysical Journal. 98: 611a-612a. DOI: 10.1016/J.Bpj.2009.12.3336  0.538
2010 Torella JP, Santoso Y, Holden SJ, Hohlbein J, Joyce CM, Potapova O, Grindley ND, Kapanidis AN. Separating Static and Dynamic Heterogeneity in Single-Molecule FRET Experiments with Burst Variance Analysis (BVA) Biophysical Journal. 98: 591a. DOI: 10.1016/J.Bpj.2009.12.3213  0.338
2010 Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN. Conformational Changes in DNA Polymerase I Revealed by Single-Molecule FRET Biophysical Journal. 98: 436a-437a. DOI: 10.1016/J.Bpj.2009.12.2370  0.602
2008 Joyce CM, Potapova O, Delucia AM, Huang X, Basu VP, Grindley ND. Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity. Biochemistry. 47: 6103-16. PMID 18473481 DOI: 10.1021/Bi7021848  0.577
2007 DeLucia AM, Grindley ND, Joyce CM. Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence. Biochemistry. 46: 10790-803. PMID 17725324 DOI: 10.1021/Bi7006756  0.625
2006 DeLucia AM, Chaudhuri S, Potapova O, Grindley ND, Joyce CM. The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases. The Journal of Biological Chemistry. 281: 27286-91. PMID 16831866 DOI: 10.1074/Jbc.M604393200  0.566
2006 Potapova O, Chan C, DeLucia AM, Helquist SA, Kool ET, Grindley ND, Joyce CM. DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Biochemistry. 45: 890-8. PMID 16411765 DOI: 10.1021/Bi051792I  0.414
2004 Joyce CM, Benkovic SJ. DNA polymerase fidelity: Kinetics, structure, and checkpoints Biochemistry. 43: 14317-14324. PMID 15533035 DOI: 10.1021/Bi048422Z  0.478
2004 Joyce CM. T4 replication: What does "processivity" really mean? Proceedings of the National Academy of Sciences of the United States of America. 101: 8255-8256. PMID 15159531 DOI: 10.1073/Pnas.0402850101  0.484
2004 Wang CX, Zakharova E, Li J, Joyce CM, Wang J, Konigsberg W. Pre-Steady-State Kinetics of RB69 DNA Polymerase and Its Exo Domain Mutants: Effect of pH and Thiophosphoryl Linkages on 3′-5′ Exonuclease Activity Biochemistry. 43: 3853-3861. PMID 15049692 DOI: 10.1021/bi0302292  0.488
2004 Gardner AF, Joyce CM, Jack WE. Comparative Kinetics of Nucleotide Analog Incorporation by Vent DNA Polymerase Journal of Biological Chemistry. 279: 11834-11842. PMID 14699133 DOI: 10.1074/Jbc.M308286200  0.61
2003 Purohit V, Grindley ND, Joyce CM. Use of 2-aminopurine fluorescence to examine conformational changes during nucleotide incorporation by DNA polymerase I (Klenow fragment). Biochemistry. 42: 10200-11. PMID 12939148 DOI: 10.1021/Bi0341206  0.447
2003 DeLucia AM, Grindley ND, Joyce CM. An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides. Nucleic Acids Research. 31: 4129-37. PMID 12853630 DOI: 10.1093/Nar/Gkg417  0.615
2003 Turner RM, Grindley ND, Joyce CM. Interaction of DNA polymerase I (Klenow fragment) with the single-stranded template beyond the site of synthesis. Biochemistry. 42: 2373-85. PMID 12600204 DOI: 10.1021/Bi026566C  0.586
2002 Potapova O, Grindley ND, Joyce CM. The mutational specificity of the Dbh lesion bypass polymerase and its implications. The Journal of Biological Chemistry. 277: 28157-66. PMID 12023283 DOI: 10.1074/Jbc.M202607200  0.557
2002 Lam WC, Thompson EH, Potapova O, Sun XC, Joyce CM, Millar DP. 3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting. Biochemistry. 41: 3943-51. PMID 11900537 DOI: 10.1021/Bi0120603  0.646
2002 Minnick DT, Liu L, Grindley ND, Kunkel TA, Joyce CM. Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation. Proceedings of the National Academy of Sciences of the United States of America. 99: 1194-9. PMID 11830658 DOI: 10.1073/Pnas.032457899  0.577
2002 Thompson EH, Bailey MF, van der Schans EJ, Joyce CM, Millar DP. Determinants of DNA mismatch recognition within the polymerase domain of the Klenow fragment. Biochemistry. 41: 713-22. PMID 11790092 DOI: 10.1021/Bi0114271  0.566
2001 Lin TC, Wang CX, Joyce CM, Konigsberg WH. 3'-5' Exonucleolytic activity of DNA polymerases: structural features that allow kinetic discrimination between ribo- and deoxyribonucleotide residues. Biochemistry. 40: 8749-55. PMID 11467934 DOI: 10.1021/Bi0105936  0.601
2001 Xu Y, Potapova O, Leschziner AE, Grindley ND, Joyce CM. Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate. The Journal of Biological Chemistry. 276: 30167-77. PMID 11349126 DOI: 10.1074/Jbc.M100985200  0.633
2000 Xu Y, Grindley ND, Joyce CM. Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. The Journal of Biological Chemistry. 275: 20949-55. PMID 10806216 DOI: 10.1074/Jbc.M909135199  0.636
1999 Minnick DT, Bebenek K, Osheroff WP, Turner RM, Astatke M, Liu L, Kunkel TA, Joyce CM. Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment). The Journal of Biological Chemistry. 274: 3067-75. PMID 9915846 DOI: 10.1074/Jbc.274.5.3067  0.508
1998 Astatke M, Grindley ND, Joyce CM. How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides. Journal of Molecular Biology. 278: 147-65. PMID 9571040 DOI: 10.1006/Jmbi.1998.1672  0.508
1998 Astatke M, Ng K, Grindley ND, Joyce CM. A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 95: 3402-7. PMID 9520378 DOI: 10.1073/Pnas.95.7.3402  0.605
1998 Furey WS, Joyce CM, Osborne MA, Klenerman D, Peliska JA, Balasubramanian S. Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment. Biochemistry. 37: 2979-90. PMID 9485450 DOI: 10.1021/bi9719758  0.496
1998 Lam WC, Van Der Schans EJC, Joyce CM, Millar DP. Effects of mutations on the partitioning of DNA substrates between the polymerase and 3'-5' exonuclease sites of DNA polymerase I (Klenow fragment) Biochemistry. 37: 1513-1522. PMID 9484221 DOI: 10.1021/Bi9720181  0.618
1997 Xu Y, Derbyshire V, Ng K, Sun XC, Grindley ND, Joyce CM. Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli. Journal of Molecular Biology. 268: 284-302. PMID 9159471 DOI: 10.1006/Jmbi.1997.0967  0.597
1997 Bell JB, Eckert KA, Joyce CM, Kunkel TA. Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain. The Journal of Biological Chemistry. 272: 7345-51. PMID 9054433 DOI: 10.1074/Jbc.272.11.7345  0.489
1997 Joyce CM. Choosing the right sugar: How polymerases select a nucleotide substrate Proceedings of the National Academy of Sciences of the United States of America. 94: 1619-1622. PMID 9050827 DOI: 10.1073/Pnas.94.5.1619  0.557
1996 Minnick DT, Astatke M, Joyce CM, Kunkel TA. A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. The Journal of Biological Chemistry. 271: 24954-61. PMID 8798775 DOI: 10.1074/Jbc.271.40.24954  0.601
1995 Derbyshire V, Pinsonneault JK, Joyce CM. Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases. Methods in Enzymology. 262: 363-85. PMID 8594362 DOI: 10.1016/0076-6879(95)62030-3  0.639
1995 Joyce CM, Derbyshire V. Purification of Escherichia coli DNA polymerase I and Klenow fragment Methods in Enzymology. 262: 3-13. PMID 8594356 DOI: 10.1016/0076-6879(95)62003-6  0.528
1995 Astatke M, Grindley ND, Joyce CM. Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment). The Journal of Biological Chemistry. 270: 1945-54. PMID 7829532 DOI: 10.1074/Jbc.270.4.1945  0.562
1994 Steitz TA, Smerdon SJ, Jager J, Joyce CM. A unified polymerase mechanism for nonhomologous DNA and RNA polymerases Science. 266: 2022-2025. PMID 7528445 DOI: 10.1126/Science.7528445  0.405
1994 Joyce CM, Steitz TA. Function and structure relationships in DNA polymerases Annual Review of Biochemistry. 63: 777-822. PMID 7526780 DOI: 10.1146/Annurev.Bi.63.070194.004021  0.523
1993 Derbyshire V, Astatke M, Joyce CM. Re-engineering the polymerase domain of klenow fragment and evaluation of overproduction and purification strategies Nucleic Acids Research. 21: 5439-5448. PMID 8265361 DOI: 10.1093/Nar/21.23.5439  0.372
1992 Polesky AH, Dahlberg ME, Benkovic SJ, Grindley ND, Joyce CM. Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli. The Journal of Biological Chemistry. 267: 8417-28. PMID 1569092  0.448
1992 Joyce CM, Sun XC, Grindley ND. Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment). The Journal of Biological Chemistry. 267: 24485-500. PMID 1447195  0.558
1991 Eger BT, Kuchta RD, Carroll SS, Benkovic PA, Dahlberg ME, Joyce CM, Benkovic SJ. Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-) Biochemistry. 30: 1441-1448. PMID 1991125 DOI: 10.1021/Bi00219A039  0.605
1991 Derbyshire V, Grindley ND, Joyce CM. The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. The Embo Journal. 10: 17-24. PMID 1989882 DOI: 10.1002/J.1460-2075.1991.Tb07916.X  0.516
1991 Joyce CM. Can DNA polymerase I (Klenow fragment) serve as a model for other polymerases?. Current Opinion in Structural Biology 1991, 1:123-129 Current Opinion in Structural Biology. 1: 123-129. DOI: 10.1016/0959-440X(91)90020-T  0.529
1990 Polesky AH, Steitz TA, Grindley ND, Joyce CM. Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. The Journal of Biological Chemistry. 265: 14579-91. PMID 2201688  0.527
1990 Bebenek K, Joyce CM, Fitzgerald MP, Kunkel TA. The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I Journal of Biological Chemistry. 265: 13878-13887. PMID 2199444  0.54
1989 Joyce CM. How DNA travels between the separate polymerase and 3'-5'-exonuclease sites of DNA polymerase I (Klenow fragment) Journal of Biological Chemistry. 264: 10858-10866. PMID 2659595  0.577
1988 Derbyshire V, Freemont PS, Sanderson MR, Beese L, Friedman JM, Joyce CM, Steitz TA. Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. Science (New York, N.Y.). 240: 199-201. PMID 2832946 DOI: 10.1126/Science.2832946  0.478
1987 Clark JM, Joyce CM, Beardsley GP. Novel blunt-end addition reactions catalyzed by DNA polymerase I of Escherichia coli. Journal of Molecular Biology. 198: 123-7. PMID 3323527 DOI: 10.1016/0022-2836(87)90462-1  0.528
1987 Joyce CM, Steitz TA. DNA polymerase I: from crystal structure to function via genetics Trends in Biochemical Sciences. 12: 288-292. DOI: 10.1016/0968-0004(87)90143-5  0.527
1986 Freemont PS, Ollis DL, Steitz TA, Joyce CM. A domain of the Klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity Proteins: Structure, Function and Genetics. 1: 66-73. PMID 3329725 DOI: 10.1002/Prot.340010111  0.537
1985 Joyce CM, Fujii DM, Laks HS, Hughes CM, Grindley ND. Genetic mapping and DNA sequence analysis of mutations in the polA gene of Escherichia coli. Journal of Molecular Biology. 186: 283-93. PMID 3910840 DOI: 10.1016/0022-2836(85)90105-6  0.581
1983 Joyce CM, Grindley ND. Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 80: 1830-4. PMID 6340110 DOI: 10.1073/Pnas.80.7.1830  0.532
1983 Kelley WS, Joyce CM. Genetic characterization of early amber mutations in the Escherichia coli polA gene and purification of the amber peptides. Journal of Molecular Biology. 164: 529-60. PMID 6302278 DOI: 10.1016/0022-2836(83)90049-9  0.423
1982 Joyce CM, Kelley WS, Grindley ND. Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I. The Journal of Biological Chemistry. 257: 1958-64. PMID 6276402  0.447
1980 Grindley ND, Joyce CM. Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903. Proceedings of the National Academy of Sciences of the United States of America. 77: 7176-80. PMID 6261245  0.398
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