John W. Weisel, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Blood clotting, fibrinogen
Website:
http://www.med.upenn.edu/apps/faculty/index.php/g275/p20310

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Year Citation  Score
2020 Tomaiuolo M, Litvinov RI, Weisel JW, Stalker TJ. Use of electron microscopy to study platelets and thrombi. Platelets. 1-9. PMID 32423268 DOI: 10.1080/09537104.2020.1763939  0.6
2020 Chernysh IN, Spiewak R, Cambor CL, Purohit PK, Weisel JW. Structure, mechanical properties, and modeling of cyclically compressed pulmonary emboli. Journal of the Mechanical Behavior of Biomedical Materials. 105: 103699. PMID 32279846 DOI: 10.1016/j.jmbbm.2020.103699  0.52
2020 Mordakhanova ER, Nevzorova TA, Synbulatova GE, Rauova L, Weisel JW, Litvinov RI. Platelet Activation in Heparin-Induced Thrombocytopenia is Followed by Platelet Death via Complex Apoptotic and Non-Apoptotic Pathways. International Journal of Molecular Sciences. 21. PMID 32272655 DOI: 10.3390/ijms21072556  0.6
2020 Chernysh IN, Nagaswami C, Kosolapova S, Peshkova AD, Cuker A, Cines DB, Cambor CL, Litvinov RI, Weisel JW. The distinctive structure and composition of arterial and venous thrombi and pulmonary emboli. Scientific Reports. 10: 5112. PMID 32198356 DOI: 10.1038/s41598-020-59526-x  0.6
2019 Andrianova IA, Ponomareva AA, Mordakhanova ER, Le Minh G, Daminova AG, Nevzorova TA, Rauova L, Litvinov RI, Weisel JW. In systemic lupus erythematosus anti-dsDNA antibodies can promote thrombosis through direct platelet activation. Journal of Autoimmunity. 102355. PMID 31732191 DOI: 10.1016/j.jaut.2019.102355  0.6
2019 Litvinov RI, Weisel JW. Could Some Nonhemostatic Plasma Proteins Serve as Refuse Collectors for Fibrin(ogen)? Thrombosis and Haemostasis. PMID 31659735 DOI: 10.1055/s-0039-1697619  0.6
2019 Peshkova AD, Safiullina SI, Evtugina NG, Baras YS, Ataullakhanov FI, Weisel JW, Litvinov RI. Premorbid Hemostasis in Women with a History of Pregnancy Loss. Thrombosis and Haemostasis. PMID 31587245 DOI: 10.1055/s-0039-1696972  0.6
2019 Le Minh G, Peshkova AD, Andrianova IA, Weisel JW, Litvinov RI. Differential sensitivity of various markers of platelet activation with adenosine diphosphate. Bionanoscience. 9: 53-58. PMID 31534882  0.6
2019 Litvinov RI, Nabiullina RM, Zubairova LD, Shakurova MA, Andrianova IA, Weisel JW. Lytic Susceptibility, Structure, and Mechanical Properties of Fibrin in Systemic Lupus Erythematosus. Frontiers in Immunology. 10: 1626. PMID 31379831 DOI: 10.3389/fimmu.2019.01626  0.6
2019 Nevzorova TA, Mordakhanova ER, Daminova AG, Ponomareva AA, Andrianova IA, Le Minh G, Rauova L, Litvinov RI, Weisel JW. Platelet factor 4-containing immune complexes induce platelet activation followed by calpain-dependent platelet death. Cell Death Discovery. 5: 106. PMID 31263574 DOI: 10.1038/s41420-019-0188-0  0.6
2019 Litvinov RI, Mravic M, Zhu H, Weisel JW, DeGrado WF, Bennett JS. Unique transmembrane domain interactions differentially modulate integrin αvβ3 and αIIbβ3 function. Proceedings of the National Academy of Sciences of the United States of America. PMID 31160446 DOI: 10.1073/pnas.1904867116  0.6
2019 Britton S, Kim O, Pancaldi F, Xu Z, Litvinov RI, Weisel JW, Alber M. Contribution of nascent cohesive fiber-fiber interactions to the non-linear elasticity of fibrin networks under tensile load. Acta Biomaterialia. PMID 31152942 DOI: 10.1016/j.actbio.2019.05.068  0.6
2019 Kim OV, Nevzorova TA, Mordakhanova ER, Ponomareva AA, Andrianova IA, Le Minh G, Daminova AG, Peshkova AD, Alber MS, Vagin O, Litvinov RI, Weisel JW. Fatal dysfunction and disintegration of thrombin-stimulated platelets. Haematologica. PMID 30792211 DOI: 10.3324/haematol.2018.202309  0.6
2019 Protopopova AD, Ramirez A, Klinov DV, Litvinov RI, Weisel JW. Factor XIII topology: organization of B subunits and changes with activation studied with single-molecule atomic force microscopy. Journal of Thrombosis and Haemostasis : Jth. PMID 30773828 DOI: 10.1111/jth.14412  0.6
2019 Tutwiler V, Peshkova AD, Le Minh G, Zaitsev S, Litvinov RI, Cines DB, Weisel JW. Blood clot contraction differentially modulates internal and external fibrinolysis. Journal of Thrombosis and Haemostasis : Jth. 17: 361-370. PMID 30582674 DOI: 10.1111/jth.14370  0.6
2018 Peshkova AD, Malyasyov DV, Bredikhin RA, Le Minh G, Andrianova IA, Tutwiler V, Nagaswami C, Weisel JW, Litvinov RI. Reduced Contraction of Blood Clots in Venous Thromboembolism Is a Potential Thrombogenic and Embologenic Mechanism. Th Open : Companion Journal to Thrombosis and Haemostasis. 2: e104-e115. PMID 31249934 DOI: 10.1055/s-0038-1635572  0.6
2018 Tutwiler V, Mukhitov AR, Peshkova AD, Le Minh G, Khismatullin RR, Vicksman J, Nagaswami C, Litvinov RI, Weisel JW. Shape changes of erythrocytes during blood clot contraction and the structure of polyhedrocytes. Scientific Reports. 8: 17907. PMID 30559364 DOI: 10.1038/s41598-018-35849-8  0.6
2018 Abu-Fanne R, Stepanova V, Litvinov RI, Abdeen S, Bdeir K, Higazi M, Maraga E, Nagaswami C, Mukhitov AR, Weisel JW, Cines DB, Higazi AA. Neutrophil alpha-defensins promote thrombosis in vivo by altering fibrin formation, structure and stability. Blood. PMID 30442678 DOI: 10.1182/blood-2018-07-861237  0.6
2018 Litvinov RI, Kononova O, Zhmurov A, Marx KA, Barsegov V, Thirumalai D, Weisel JW. Regulatory element in fibrin triggers tension-activated transition from catch to slip bonds. Proceedings of the National Academy of Sciences of the United States of America. PMID 30087181 DOI: 10.1073/pnas.1802576115  0.6
2018 Zhmurov A, Protopopova AD, Litvinov RI, Zhukov P, Weisel JW, Barsegov V. Atomic Structural Models of Fibrin Oligomers. Structure (London, England : 1993). PMID 29754827 DOI: 10.1016/j.str.2018.04.005  0.6
2017 Xu S, Xu Z, Kim OV, Litvinov RI, Weisel JW, Alber M. Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow. Journal of the Royal Society, Interface. 14. PMID 29142014 DOI: 10.1098/rsif.2017.0441  0.6
2017 Nevzorova TA, Zhao Q, Lomakin YA, Ponomareva AA, Mukhitov AR, Purohit PK, Weisel JW, Litvinov RI. Single-Molecule Interactions of a Monoclonal Anti-DNA Antibody with DNA. Bionanoscience. 7: 132-147. PMID 29104846 DOI: 10.1007/s12668-016-0303-0  0.6
2017 Kim OV, Litvinov RI, Alber MS, Weisel JW. Quantitative structural mechanobiology of platelet-driven blood clot contraction. Nature Communications. 8: 1274. PMID 29097692 DOI: 10.1038/s41467-017-00885-x  0.6
2017 Höök P, Litvinov RI, Kim OV, Xu S, Xu Z, Bennett JS, Alber MS, Weisel JW. Strong Binding of Platelet Integrin αIIbβ3 to Fibrin Clots: Potential Target to Destabilize Thrombi. Scientific Reports. 7: 13001. PMID 29021578 DOI: 10.1038/s41598-017-12615-w  0.6
2017 Protopopova AD, Litvinov RI, Galanakis DK, Nagaswami C, Barinov NA, Mukhitov AR, Klinov DV, Weisel JW. Morphometric characterization of fibrinogen's αC regions and their role in fibrin self-assembly and molecular organization. Nanoscale. PMID 28884176 DOI: 10.1039/c7nr04413e  0.6
2017 Zuev YF, Litvinov RI, Sitnitsky AE, Idiyatullin BZ, Bakirova DR, Galanakis D, Zhmurov A, Barsegov V, Weisel JW. Conformational Flexibility and Self-Association of Fibrinogen in Concentrated Solutions. The Journal of Physical Chemistry. B. PMID 28742964 DOI: 10.1021/acs.jpcb.7b05654  0.6
2017 Peshkova AD, Le Minh G, Tutwiler V, Andrianova IA, Weisel JW, Litvinov RI. Activated Monocytes Enhance Platelet-Driven Contraction of Blood Clots via Tissue Factor Expression. Scientific Reports. 7: 5149. PMID 28698680 DOI: 10.1038/s41598-017-05601-9  0.6
2017 Litvinov RI, Weisel JW. Role of red blood cells in haemostasis and thrombosis. Isbt Science Series. 12: 176-183. PMID 28458720 DOI: 10.1111/voxs.12331  0.6
2017 Kononova O, Litvinov RI, Blokhin DS, Klochkov VV, Weisel JW, Bennett JS, Barsegov V. Mechanistic Basis for the Binding of RGD- and AGDV-Peptides to the Platelet Integrin αIIbβ3. Biochemistry. PMID 28277676 DOI: 10.1021/acs.biochem.6b01113  0.6
2017 Tutwiler V, Wang H, Litvinov RI, Weisel JW, Shenoy VB. Interplay of Platelet Contractility and Elasticity of Fibrin/Erythrocytes in Blood Clot Retraction. Biophysical Journal. 112: 714-723. PMID 28256231 DOI: 10.1016/j.bpj.2017.01.005  0.6
2017 Weisel JW, Litvinov RI. Fibrin Formation, Structure and Properties. Sub-Cellular Biochemistry. 82: 405-456. PMID 28101869 DOI: 10.1007/978-3-319-49674-0_13  0.6
2016 Tutwiler V, Peshkova AD, Andrianova IA, Khasanova DR, Weisel JW, Litvinov RI. Contraction of Blood Clots Is Impaired in Acute Ischemic Stroke. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27908894 DOI: 10.1161/ATVBAHA.116.308622  0.6
2016 Zhmurov A, Protopopova AD, Litvinov RI, Zhukov P, Mukhitov AR, Weisel JW, Barsegov V. Structural Basis of Interfacial Flexibility in Fibrin Oligomers. Structure (London, England : 1993). PMID 27692965 DOI: 10.1016/j.str.2016.08.009  0.6
2016 Litvinov RI, Weisel JW. Fibrin mechanical properties and their structural origins. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27553509 DOI: 10.1016/j.matbio.2016.08.003  0.6
2016 Litvinov RI, Weisel JW. What Is the Biological and Clinical Relevance of Fibrin? Seminars in Thrombosis and Hemostasis. PMID 27056152 DOI: 10.1055/s-0036-1571342  0.6
2016 Li W, Sigley J, Pieters M, Helms CC, Nagaswami C, Weisel JW, Guthold M. Fibrin Fiber Stiffness Is Strongly Affected by Fiber Diameter, but Not by Fibrinogen Glycation. Biophysical Journal. 110: 1400-1410. PMID 27028649 DOI: 10.1016/j.bpj.2016.02.021  0.64
2016 Slee JB, Alferiev IS, Nagaswami C, Weisel JW, Levy RJ, Fishbein I, Stachelek SJ. Enhanced biocompatibility of CD47-functionalized vascular stents. Biomaterials. 87: 82-92. PMID 26914699 DOI: 10.1016/j.biomaterials.2016.02.008  0.64
2016 Litvinov RI, Farrell DH, Weisel JW, Bennett JS. The Platelet Integrin αIIbβ3 Differentially Interacts with Fibrin Versus Fibrinogen. The Journal of Biological Chemistry. PMID 26867579 DOI: 10.1074/jbc.M115.706861  0.64
2016 Galanakis DK, Spitzer ED, Perrotta P, Nagaswami C, Marchi R, Spitzer S, Refailovich M, Smith RE, Zhang L, Marmorat C, Weisel JW. Thrombosis-associated antifibrinogen IgG1 κ impairs fibrin polymerization and enhances platelet activation. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. PMID 26849715 DOI: 10.1097/MBC.0000000000000533  0.64
2015 Zubairova LD, Nabiullina RM, Nagaswami C, Zuev YF, Mustafin IG, Litvinov RI, Weisel JW. Circulating Microparticles Alter Formation, Structure, and Properties of Fibrin Clots. Scientific Reports. 5: 17611. PMID 26635081 DOI: 10.1038/srep17611  0.64
2015 Tutwiler V, Litvinov RI, Lozhkin AP, Peshkova AD, Lebedeva T, Ataullakhanov FI, Spiller KL, Cines DB, Weisel JW. Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the blood. Blood. PMID 26603837 DOI: 10.1182/blood-2015-05-647560  0.64
2015 Litvinov RI, Weisel JW. Not fibrin(ogen), but fibrinogen or fibrin. Blood. 126: 1977-8. PMID 26494920 DOI: 10.1182/blood-2015-08-662551  0.64
2015 Kim OV, Liang X, Litvinov RI, Weisel JW, Alber MS, Purohit PK. Foam-like compression behavior of fibrin networks. Biomechanics and Modeling in Mechanobiology. PMID 25982442 DOI: 10.1007/s10237-015-0683-z  0.64
2015 Badiei N, Sowedan AM, Curtis DJ, Brown MR, Lawrence MJ, Campbell AI, Sabra A, Evans PA, Weisel JW, Chernysh IN, Nagaswami C, Williams PR, Hawkins K. Effects of unidirectional flow shear stresses on the formation, fractal microstructure and rigidity of incipient whole blood clots and fibrin gels. Clinical Hemorheology and Microcirculation. PMID 25624413 DOI: 10.3233/CH-151924  0.64
2015 Chernysh IN, Everbach CE, Purohit PK, Weisel JW. Molecular mechanisms of the effect of ultrasound on the fibrinolysis of clots. Journal of Thrombosis and Haemostasis : Jth. 13: 601-9. PMID 25619618 DOI: 10.1111/jth.12857  0.64
2015 Rocco M, Weisel JW. Exposed: the elusive αC regions in fibrinogen, fibrin protofibrils and fibers. Journal of Thrombosis and Haemostasis : Jth. 13: 567-9. PMID 25556398 DOI: 10.1111/jth.12835  0.64
2015 Lawrence MJ, Sabra A, Mills G, Pillai SG, Abdullah W, Hawkins K, Morris RH, Davidson SJ, D'Silva LA, Curtis DJ, Brown MR, Weisel JW, Williams PR, Evans PA. A new biomarker quantifies differences in clot microstructure in patients with venous thromboembolism. British Journal of Haematology. 168: 571-5. PMID 25302653 DOI: 10.1111/bjh.13173  0.64
2014 Weisel JW. Monitoring coagulopathies in fluid resuscitation for trauma or surgery. Thrombosis Research. 134: 535-6. PMID 25087888 DOI: 10.1016/j.thromres.2014.07.017  0.64
2014 Skewis LR, Lebedeva T, Papkov V, Thayer EC, Massefski W, Cuker A, Nagaswami C, Litvinov RI, Kowalska MA, Rauova L, Poncz M, Weisel JW, Lowery TJ, Cines DB. T2 magnetic resonance: a diagnostic platform for studying integrated hemostasis in whole blood--proof of concept. Clinical Chemistry. 60: 1174-82. PMID 24958814 DOI: 10.1373/clinchem.2014.223735  0.64
2014 Kim OV, Litvinov RI, Weisel JW, Alber MS. Structural basis for the nonlinear mechanics of fibrin networks under compression. Biomaterials. 35: 6739-49. PMID 24840618 DOI: 10.1016/j.biomaterials.2014.04.056  0.64
2014 Martinez MR, Cuker A, Mills AM, Crichlow A, Lightfoot RT, Chernysh IN, Nagaswami C, Weisel JW, Ischiropoulos H. Enhanced lysis and accelerated establishment of viscoelastic properties of fibrin clots are associated with pulmonary embolism. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L397-404. PMID 24414255 DOI: 10.1152/ajplung.00265.2013  0.64
2014 Cines DB, Lebedeva T, Nagaswami C, Hayes V, Massefski W, Litvinov RI, Rauova L, Lowery TJ, Weisel JW. Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin. Blood. 123: 1596-603. PMID 24335500 DOI: 10.1182/blood-2013-08-523860  0.64
2014 Bannish BE, Keener JP, Woodbury M, Weisel JW, Fogelson AL. Modelling fibrinolysis: 1D continuum models. Mathematical Medicine and Biology : a Journal of the Ima. 31: 45-64. PMID 23220467 DOI: 10.1093/imammb/dqs030  0.64
2014 Chen J, Kim OV, Litvinov RI, Weisel JW, Alber MS, Chen DZ. An automated approach for fibrin network segmentation and structure identification in 3D confocal microscopy images Proceedings - Ieee Symposium On Computer-Based Medical Systems. 173-178. DOI: 10.1109/CBMS.2014.62  0.64
2014 Chen J, Kim OV, Litvinov RI, Weisel JW, Alber MS, Chen DZ. An automated approach for fibrin network segmentation and structure identification in 3D confocal microscopy images Proceedings - Ieee Symposium On Computer-Based Medical Systems. 173-178. DOI: 10.1109/CBMS.2014.62  0.6
2013 Litvinov RI, Yarovoi SV, Rauova L, Barsegov V, Sachais BS, Rux AH, Hinds JL, Arepally GM, Cines DB, Weisel JW. Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4. The Journal of Biological Chemistry. 288: 33060-70. PMID 24097975 DOI: 10.1074/jbc.M113.481598  0.64
2013 Litvinov RI, Weisel JW. Shear strengthens fibrin: the knob-hole interactions display 'catch-slip' kinetics. Journal of Thrombosis and Haemostasis : Jth. 11: 1933-5. PMID 23937213 DOI: 10.1111/jth.12374  0.64
2013 Martinez M, Weisel JW, Ischiropoulos H. Functional impact of oxidative posttranslational modifications on fibrinogen and fibrin clots. Free Radical Biology & Medicine. 65: 411-8. PMID 23851017 DOI: 10.1016/j.freeradbiomed.2013.06.039  0.64
2013 Weisel JW, Litvinov RI. Adaptation of fibrous biopolymers to recurring increasing strains. Proceedings of the National Academy of Sciences of the United States of America. 110: 12164-5. PMID 23842087 DOI: 10.1073/pnas.1310351110  0.64
2013 Kononova O, Litvinov RI, Zhmurov A, Alekseenko A, Cheng CH, Agarwal S, Marx KA, Weisel JW, Barsegov V. Molecular mechanisms, thermodynamics, and dissociation kinetics of knob-hole interactions in fibrin. The Journal of Biological Chemistry. 288: 22681-92. PMID 23720752 DOI: 10.1074/jbc.M113.472365  0.64
2013 Eckmann DM, Tsai IY, Tomczyk N, Weisel JW, Composto RJ. Hyaluronan and dextran modified tubes resist cellular activation with blood contact. Colloids and Surfaces. B, Biointerfaces. 108: 44-51. PMID 23524078 DOI: 10.1016/j.colsurfb.2013.02.013  0.64
2013 Wang Y, Zhao L, Suzuki A, Lian L, Min SH, Wang Z, Litvinov RI, Stalker TJ, Yago T, Klopocki AG, Schmidtke DW, Yin H, Choi JK, McEver RP, Weisel JW, et al. Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion. Blood. 121: 2743-52. PMID 23372168 DOI: 10.1182/blood-2012-07-445205  0.64
2013 Weisel JW, Litvinov RI. Mechanisms of fibrin polymerization and clinical implications. Blood. 121: 1712-9. PMID 23305734 DOI: 10.1182/blood-2012-09-306639  0.64
2013 Hategan A, Gersh KC, Safer D, Weisel JW. Visualization of the dynamics of fibrin clot growth 1 molecule at a time by total internal reflection fluorescence microscopy. Blood. 121: 1455-8. PMID 23233658 DOI: 10.1182/blood-2012-08-451518  0.64
2012 Pieters M, Undas A, Marchi R, De Maat MPM, Weisel JW, Ariëns RAS. An international study on the standardization of fibrin clot permeability measurement: Methodological considerations and implications for healthy control values Journal of Thrombosis and Haemostasis. 10: 2179-2181. PMID 23193585 DOI: 10.1111/j.1538-7836.2012.04883.x  0.64
2012 Chernysh IN, Nagaswami C, Purohit PK, Weisel JW. Fibrin clots are equilibrium polymers that can be remodeled without proteolytic digestion. Scientific Reports. 2: 879. PMID 23170200 DOI: 10.1038/srep00879  0.64
2012 Litvinov RI, Faizullin DA, Zuev YF, Weisel JW. The α-helix to β-sheet transition in stretched and compressed hydrated fibrin clots. Biophysical Journal. 103: 1020-7. PMID 23009851 DOI: 10.1016/j.bpj.2012.07.046  0.64
2012 Zhmurov A, Kononova O, Litvinov RI, Dima RI, Barsegov V, Weisel JW. Mechanical transition from α-helical coiled coils to β-sheets in fibrin(ogen). Journal of the American Chemical Society. 134: 20396-402. PMID 22953986 DOI: 10.1021/ja3076428  0.64
2012 Litvinov RI, Mekler A, Shuman H, Bennett JS, Barsegov V, Weisel JW. Resolving two-dimensional kinetics of the integrin αIIbβ3-fibrinogen interactions using binding-unbinding correlation spectroscopy. The Journal of Biological Chemistry. 287: 35275-85. PMID 22893701 DOI: 10.1074/jbc.M112.404848  0.64
2012 Finley MJ, Rauova L, Alferiev IS, Weisel JW, Levy RJ, Stachelek SJ. Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces. Biomaterials. 33: 5803-11. PMID 22613135 DOI: 10.1016/j.biomaterials.2012.04.051  0.64
2012 Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB. Dynamic antibody-binding properties in the pathogenesis of HIT. Blood. 120: 1137-42. PMID 22577175 DOI: 10.1182/blood-2012-01-407262  0.64
2012 Tsurupa G, Pechik I, Litvinov RI, Hantgan RR, Tjandra N, Weisel JW, Medved L. On the mechanism of αC polymer formation in fibrin. Biochemistry. 51: 2526-38. PMID 22397628 DOI: 10.1021/bi2017848  0.64
2012 Sun JE, Vranic J, Composto RJ, Streu C, Billings PC, Bennett JS, Weisel JW, Litvinov RI. Bimolecular integrin-ligand interactions quantified using peptide-functionalized dextran-coated microparticles. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 84-92. PMID 22120019 DOI: 10.1039/c1ib00085c  0.64
2012 Silvain J, Nagaswami C, Weisel JW, Collet JP, Montalescot G. Reply Journal of the American College of Cardiology. 59: 93-94. DOI: 10.1016/j.jacc.2011.09.042  0.64
2011 Zhmurov A, Brown AE, Litvinov RI, Dima RI, Weisel JW, Barsegov V. Mechanism of fibrin(ogen) forced unfolding. Structure (London, England : 1993). 19: 1615-24. PMID 22078561 DOI: 10.1016/j.str.2011.08.013  0.64
2011 Schmaier AA, Stalker TJ, Runge JJ, Lee D, Nagaswami C, Mericko P, Chen M, Cliché S, Gariépy C, Brass LF, Hammer DA, Weisel JW, Rosenthal K, Kahn ML. Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease. Blood. 118: 3661-9. PMID 21816834 DOI: 10.1182/blood-2011-02-338244  0.64
2011 Tsurupa G, Mahid A, Veklich Y, Weisel JW, Medved L. Structure, stability, and interaction of fibrin αC-domain polymers. Biochemistry. 50: 8028-37. PMID 21806028 DOI: 10.1021/bi2008189  0.64
2011 Silvain J, Pena A, Vignalou JB, Hulot JS, Galier S, Cayla G, Bellemain-Appaix A, Barthélémy O, Beygui F, Bal-dit-Sollier C, Drouet L, Weisel JW, Montalescot G, Collet JP. FXIII-A Leu34 genetic variant in premature coronary artery disease: a genotype--phenotype case control study. Thrombosis and Haemostasis. 106: 511-20. PMID 21800001 DOI: 10.1160/TH11-01-0027  0.64
2011 Silvain J, Collet JP, Nagaswami C, Beygui F, Edmondson KE, Bellemain-Appaix A, Cayla G, Pena A, Brugier D, Barthelemy O, Montalescot G, Weisel JW. Composition of coronary thrombus in acute myocardial infarction. Journal of the American College of Cardiology. 57: 1359-67. PMID 21414532 DOI: 10.1016/j.jacc.2010.09.077  0.64
2011 Weisel JW. Stressed fibrin lysis. Journal of Thrombosis and Haemostasis : Jth. 9: 977-8. PMID 21392256 DOI: 10.1111/j.1538-7836.2011.04258.x  0.64
2011 Gersh KC, Zaitsev S, Cines DB, Muzykantov V, Weisel JW. Flow-dependent channel formation in clots by an erythrocyte-bound fibrinolytic agent. Blood. 117: 4964-7. PMID 21389322 DOI: 10.1182/blood-2010-10-310409  0.64
2011 Purohit PK, Litvinov RI, Brown AE, Discher DE, Weisel JW. Protein unfolding accounts for the unusual mechanical behavior of fibrin networks. Acta Biomaterialia. 7: 2374-83. PMID 21342665 DOI: 10.1016/j.actbio.2011.02.026  0.64
2011 Marchi R, Rojas H, Meyer M, Castillo O, De Sáez Ruiz A, Weisel JW. A novel missense mutation in the FGB g. 3354 T>A (p. Y41N), fibrinogen Caracas VIII. Thrombosis and Haemostasis. 105: 627-34. PMID 21301788 DOI: 10.1160/TH10-03-0179  0.64
2011 Chernysh IN, Nagaswami C, Weisel JW. Visualization and identification of the structures formed during early stages of fibrin polymerization. Blood. 117: 4609-14. PMID 21248064 DOI: 10.1182/blood-2010-07-297671  0.64
2011 Litvinov RI, Barsegov V, Schissler AJ, Fisher AR, Bennett JS, Weisel JW, Shuman H. Dissociation of bimolecular αIIbβ3-fibrinogen complex under a constant tensile force. Biophysical Journal. 100: 165-73. PMID 21190668 DOI: 10.1016/j.bpj.2010.11.019  0.64
2010 Weisel JW. "Ta panta rhei". Blood. 116: 3123-4. PMID 21030568 DOI: 10.1182/blood-2010-07-294033  0.64
2010 Gersh KC, Edmondson KE, Weisel JW. Flow rate and fibrin fiber alignment. Journal of Thrombosis and Haemostasis : Jth. 8: 2826-8. PMID 20961393 DOI: 10.1111/j.1538-7836.2010.04118.x  0.64
2010 Vorjohann S, Fish RJ, Biron-Andréani C, Nagaswami C, Weisel JW, Boulot P, Reyftmann L, de Moerloose P, Neerman-Arbez M. Hypodysfibrinogenaemia due to production of mutant fibrinogen alpha-chains lacking fibrinopeptide A and polymerisation knob 'A'. Thrombosis and Haemostasis. 104: 990-7. PMID 20806111 DOI: 10.1160/TH10-03-0161  0.64
2010 Weisel JW. Biomechanics in hemostasis and thrombosis. Journal of Thrombosis and Haemostasis : Jth. 8: 1027-9. PMID 20149079 DOI: 10.1111/j.1538-7836.2010.03808.x  0.64
2010 Gersh KC, Zaitsev S, Muzykantov V, Cines DB, Weisel JW. The spatial dynamics of fibrin clot dissolution catalyzed by erythrocyte-bound vs. free fibrinolytics. Journal of Thrombosis and Haemostasis : Jth. 8: 1066-74. PMID 20149071 DOI: 10.1111/j.1538-7836.2010.03802.x  0.64
2009 Gersh KC, Nagaswami C, Weisel JW. Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes. Thrombosis and Haemostasis. 102: 1169-75. PMID 19967148 DOI: 10.1160/TH09-03-0199  0.64
2009 Sobotková A, Másová-Chrastinová L, Suttnar J, Stikarová J, Májek P, Reicheltová Z, Kotlín R, Weisel JW, Malý M, Dyr JE. Antioxidants change platelet responses to various stimulating events. Free Radical Biology & Medicine. 47: 1707-14. PMID 19766712 DOI: 10.1016/j.freeradbiomed.2009.09.015  0.64
2009 Weisel JW. Why dysfibrinogenaemias still matter. Thrombosis and Haemostasis. 102: 426-7. PMID 19718461 DOI: 10.1160/TH09-07-0432  0.64
2009 Brown AE, Litvinov RI, Discher DE, Purohit PK, Weisel JW. Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water. Science (New York, N.Y.). 325: 741-4. PMID 19661428 DOI: 10.1126/science.1172484  0.64
2009 Marchi R, Nagaswami C, Weisel JW. Fibrin formation and lysis studies in dengue virus infection. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 20: 575-82. PMID 19644359 DOI: 10.1097/MBC.0b013e32832fb1cf  0.64
2009 Ajjan RA, Standeven KF, Khanbhai M, Phoenix F, Gersh KC, Weisel JW, Kearney MT, Ariëns RA, Grant PJ. Effects of aspirin on clot structure and fibrinolysis using a novel in vitro cellular system. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 712-7. PMID 19286636 DOI: 10.1161/ATVBAHA.109.183707  0.64
2009 Gersh KC, Nagaswami C, Weisel JW, Lord ST. The presence of gamma' chain impairs fibrin polymerization. Thrombosis Research. 124: 356-63. PMID 19138790 DOI: 10.1016/j.thromres.2008.11.016  0.64
2009 Medved L, Weisel JW. Recommendations for nomenclature on fibrinogen and fibrin. Journal of Thrombosis and Haemostasis : Jth. 7: 355-9. PMID 19036059 DOI: 10.1111/j.1538-7836.2008.03242.x  0.64
2009 Janmey PA, Winer JP, Weisel JW. Fibrin gels and their clinical and bioengineering applications. Journal of the Royal Society, Interface / the Royal Society. 6: 1-10. PMID 18801715 DOI: 10.1098/rsif.2008.0327  0.64
2009 Wang Y, Litvinov RI, Chen X, Bach TL, Lian L, Petrich BG, Monkley SJ, Kanaho Y, Critchley DR, Sasaki T, Birnbaum MJ, Weisel JW, Hartwig J, Abrams CS. Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes (Journal of Clinical Investigation (2009) 119, (421) DOI:10.1172/JCI34239C1) Journal of Clinical Investigation. 119: 421.  0.64
2009 Wang Y, Litvinov RI, Chen X, Bach TL, Lian L, Petrich BG, Monkley SJ, Kanaho Y, Critchley DR, Sasaki T, Birnbaum MJ, Weisel JW, Hartwig J, Abrams CS. Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes (Journal of Clinical Investigation (2009) 119, (421) DOI:10.1172/JCI34239C1) Journal of Clinical Investigation. 119: 421.  0.6
2008 Parastatidis I, Thomson L, Burke A, Chernysh I, Nagaswami C, Visser J, Stamer S, Liebler DC, Koliakos G, Heijnen HF, Fitzgerald GA, Weisel JW, Ischiropoulos H. Fibrinogen beta-chain tyrosine nitration is a prothrombotic risk factor. The Journal of Biological Chemistry. 283: 33846-53. PMID 18818200 DOI: 10.1074/jbc.M805522200  0.64
2008 Weisel JW, Litvinov RI. The biochemical and physical process of fibrinolysis and effects of clot structure and stability on the lysis rate. Cardiovascular & Hematological Agents in Medicinal Chemistry. 6: 161-80. PMID 18673231 DOI: 10.2174/187152508784871963  0.64
2008 Rocco M, Rosano C, Weisel JW, Horita DA, Hantgan RR. Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach. Structure (London, England : 1993). 16: 954-64. PMID 18547527 DOI: 10.1016/j.str.2008.02.019  0.64
2008 Weisel JW. Biophysics. Enigmas of blood clot elasticity. Science (New York, N.Y.). 320: 456-7. PMID 18436761 DOI: 10.1126/science.1154210  0.64
2008 Pieters M, Covic N, van der Westhuizen FH, Nagaswami C, Baras Y, Toit Loots D, Jerling JC, Elgar D, Edmondson KS, van Zyl DG, Rheeder P, Weisel JW. Glycaemic control improves fibrin network characteristics in type 2 diabetes - a purified fibrinogen model. Thrombosis and Haemostasis. 99: 691-700. PMID 18392327 DOI: 10.1160/TH07-11-0699  0.64
2008 Marchi R, Carvajal Z, Weisel JW. Comparison of the effect of different homocysteine concentrations on clot formation using human plasma and purified fibrinogen. Thrombosis and Haemostasis. 99: 451-2. PMID 18278201 DOI: 10.1160/TH07-06-0404  0.64
2008 Chernysh IN, Weisel JW. Dynamic imaging of fibrin network formation correlated with other measures of polymerization. Blood. 111: 4854-61. PMID 18272815 DOI: 10.1182/blood-2007-08-105247  0.64
2008 Wang Y, Litvinov RI, Chen X, Bach TL, Lian L, Petrich BG, Monkley SJ, Kanaho Y, Critchley DR, Sasaki T, Birnbaum MJ, Weisel JW, Hartwig J, Abrams CS. Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. The Journal of Clinical Investigation. 118: 812-9. PMID 18188447 DOI: 10.1172/JCI34239  0.64
2008 Ajjan R, Lim BC, Standeven KF, Harrand R, Dolling S, Phoenix F, Greaves R, Abou-Saleh RH, Connell S, Smith DA, Weisel JW, Grant PJ, Ariëns RA. Common variation in the C-terminal region of the fibrinogen beta-chain: effects on fibrin structure, fibrinolysis and clot rigidity. Blood. 111: 643-50. PMID 17925485 DOI: 10.1182/blood-2007-05-091231  0.64
2007 Galanakis DK, Neerman-Arbez M, Scheiner T, Henschen A, Hubbs D, Nagaswami C, Weisel JW. Homophenotypic Aalpha R16H fibrinogen (Kingsport): uniquely altered polymerization associated with slower fibrinopeptide A than fibrinopeptide B release. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 18: 731-7. PMID 17982313 DOI: 10.1097/MBC.0b013e3282f10157  0.64
2007 Weisel JW. Which knobs fit into which holes in fibrin polymerization? Journal of Thrombosis and Haemostasis : Jth. 5: 2340-3. PMID 17922803 DOI: 10.1111/j.1538-7836.2007.02794.x  0.64
2007 Samuel D, Cheng H, Riley PW, Canutescu AA, Nagaswami C, Weisel JW, Bu Z, Walsh PN, Roder H. Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15693-8. PMID 17884987 DOI: 10.1073/pnas.0703080104  0.64
2007 Weisel JW. Structure of fibrin: impact on clot stability. Journal of Thrombosis and Haemostasis : Jth. 5: 116-24. PMID 17635717 DOI: 10.1111/j.1538-7836.2007.02504.x  0.64
2007 Litvinov RI, Yakovlev S, Tsurupa G, Gorkun OV, Medved L, Weisel JW. Direct evidence for specific interactions of the fibrinogen alphaC-domains with the central E region and with each other. Biochemistry. 46: 9133-42. PMID 17630702 DOI: 10.1021/bi700944j  0.64
2007 Flood VH, Nagaswami C, Chernysh IN, Al-Mondhiry HA, Weisel JW, Farrell DH. Incorporation of fibrin molecules containing fibrinopeptide A alters clot ultrastructure and decreases permeability. British Journal of Haematology. 138: 117-24. PMID 17555455 DOI: 10.1111/j.1365-2141.2007.06630.x  0.64
2007 Standeven KF, Carter AM, Grant PJ, Weisel JW, Chernysh I, Masova L, Lord ST, Ariëns RA. Functional analysis of fibrin {gamma}-chain cross-linking by activated factor XIII: determination of a cross-linking pattern that maximizes clot stiffness. Blood. 110: 902-7. PMID 17435113 DOI: 10.1182/blood-2007-01-066837  0.64
2007 Marchi R, López Ramirez Y, Nagaswami C, Masova L, Pulido A, López Mora J, Muller A, Arocha-Piñango CL, Weisel JW. Haemostatic changes related to fibrin formation and fibrinolysis during the first trimester in normal pregnancy and in recurrent miscarriage. Thrombosis and Haemostasis. 97: 552-7. PMID 17393017 DOI: 10.1160/TH06-09-0542  0.64
2007 Myers JC, Amenta PS, Dion AS, Sciancalepore JP, Nagaswami C, Weisel JW, Yurchenco PD. The molecular structure of human tissue type XV presents a unique conformation among the collagens. The Biochemical Journal. 404: 535-44. PMID 17355226 DOI: 10.1042/BJ20070201  0.64
2007 Brown AE, Litvinov RI, Discher DE, Weisel JW. Forced unfolding of coiled-coils in fibrinogen by single-molecule AFM. Biophysical Journal. 92: L39-41. PMID 17172299 DOI: 10.1529/biophysj.106.101261  0.64
2007 Pieters M, van Zyl DG, Rheeder P, Jerling JC, Loots du T, van der Westhuizen FH, Gottsche LT, Weisel JW. Glycation of fibrinogen in uncontrolled diabetic patients and the effects of glycaemic control on fibrinogen glycation. Thrombosis Research. 120: 439-46. PMID 17156827 DOI: 10.1016/j.thromres.2006.10.016  0.64
2007 Litvinov RI, Gorkun OV, Galanakis DK, Yakovlev S, Medved L, Shuman H, Weisel JW. Polymerization of fibrin: Direct observation and quantification of individual B:b knob-hole interactions. Blood. 109: 130-8. PMID 16940416 DOI: 10.1182/blood-2006-07-033910  0.64
2006 Gorkun OV, Litvinov RI, Veklich YI, Weisel JW. Interactions mediated by the N-terminus of fibrinogen's Bbeta chain. Biochemistry. 45: 14843-52. PMID 17144678 DOI: 10.1021/bi061430q  0.64
2006 Pieters M, Covic N, Loots du T, van der Westhuizen FH, van Zyl DG, Rheeder P, Jerling JC, Weisel JW. The effect of glycaemic control on fibrin network structure of type 2 diabetic subjects. Thrombosis and Haemostasis. 96: 623-9. PMID 17080220 DOI: 10.1160/TH06-07-0390  0.64
2006 Yin H, Litvinov RI, Vilaire G, Zhu H, Li W, Caputo GA, Moore DT, Lear JD, Weisel JW, Degrado WF, Bennett JS. Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb. The Journal of Biological Chemistry. 281: 36732-41. PMID 17032655 DOI: 10.1074/jbc.M605877200  0.64
2006 Collet JP, Allali Y, Lesty C, Tanguy ML, Silvain J, Ankri A, Blanchet B, Dumaine R, Gianetti J, Payot L, Weisel JW, Montalescot G. Altered fibrin architecture is associated with hypofibrinolysis and premature coronary atherothrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2567-73. PMID 16917107 DOI: 10.1161/01.ATV.0000241589.52950.4c  0.64
2006 Litvinov RI, Vilaire G, Li W, DeGrado WF, Weisel JW, Bennett JS. Activation of individual alphaIIbbeta3 integrin molecules by disruption of transmembrane domain interactions in the absence of clustering. Biochemistry. 45: 4957-64. PMID 16605263 DOI: 10.1021/bi0526581  0.64
2006 Marchi RC, Carvajal Z, Boyer-Neumann C, Anglés-Cano E, Weisel JW. Functional characterization of fibrinogen Bicêtre II: a gamma 308 Asn-->Lys mutation located near the fibrin D:D interaction sites. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 17: 193-201. PMID 16575257 DOI: 10.1097/01.mbc.0000220241.22714.68  0.64
2006 Beygui F, Collet JP, Nagaswami C, Weisel JW, Montalescot G. Images in cardiovascular medicine. Architecture of intracoronary thrombi in ST-elevation acute myocardial infarction: time makes the difference. Circulation. 113: e21-3. PMID 16418443 DOI: 10.1161/CIRCULATIONAHA.105.551705  0.64
2006 Marchi R, Carvajal Z, Meyer M, Soria J, Ruiz-Saez A, Arocha-Piñango CL, Weisel JW. Fibrinogen Guarenas, an abnormal fibrinogen with an Aalpha-chain truncation due to a nonsense mutation at Aalpha 467 Glu (GAA)-->stop (TAA). Thrombosis Research. 118: 637-50. PMID 16406498 DOI: 10.1016/j.thromres.2005.10.016  0.64
2006 Weisel JW. Fibronectin comes to the fore in thrombus growth Blood. 107: 3419-3420. DOI: 10.1182/blood-2006-02-001941  0.64
2005 Collet JP, Moen JL, Veklich YI, Gorkun OV, Lord ST, Montalescot G, Weisel JW. The alphaC domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysis. Blood. 106: 3824-30. PMID 16091450 DOI: 10.1182/blood-2005-05-2150  0.64
2005 Litvinov RI, Bennett JS, Weisel JW, Shuman H. Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy. Biophysical Journal. 89: 2824-34. PMID 16040750 DOI: 10.1529/biophysj.105.061887  0.64
2005 Litvinov RI, Gorkun OV, Owen SF, Shuman H, Weisel JW. Polymerization of fibrin: specificity, strength, and stability of knob-hole interactions studied at the single-molecule level. Blood. 106: 2944-51. PMID 15998829 DOI: 10.1182/blood-2005-05-2039  0.64
2005 Collet JP, Shuman H, Ledger RE, Lee S, Weisel JW. The elasticity of an individual fibrin fiber in a clot. Proceedings of the National Academy of Sciences of the United States of America. 102: 9133-7. PMID 15967976 DOI: 10.1073/pnas.0504120102  0.64
2005 Weisel JW. Fibrinogen and fibrin. Advances in Protein Chemistry. 70: 247-99. PMID 15837518 DOI: 10.1016/S0065-3233(05)70008-5  0.64
2005 Belkin AM, Tsurupa G, Zemskov E, Veklich Y, Weisel JW, Medved L. Transglutaminase-mediated oligomerization of the fibrin(ogen) alphaC domains promotes integrin-dependent cell adhesion and signaling. Blood. 105: 3561-8. PMID 15637140 DOI: 10.1182/blood-2004-10-4089  0.64
2005 Keller MA, Martinez J, Baradet TC, Nagaswami C, Chernysh IN, Borowski MK, Surrey S, Weisel JW. Fibrinogen Philadelphia, a hypodysfibrinogenemia characterized by abnormal polymerization and fibrinogen hypercatabolism due to gamma S378P mutation. Blood. 105: 3162-8. PMID 15632207 DOI: 10.1182/blood-2004-04-1621  0.64
2005 Rauova L, Poncz M, McKenzie SE, Reilly MP, Arepally G, Weisel JW, Nagaswami C, Cines DB, Sachais BS. Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. Blood. 105: 131-8. PMID 15304392 DOI: 10.1182/blood-2004-04-1544  0.64
2005 Weisel JW, Nagaswami C, Peterson RO. River otter hair structure facilitates interlocking to impede penetration of water and allow trapping of air Canadian Journal of Zoology. 83: 649-655. DOI: 10.1139/z05-047  0.64
2004 Weisel JW. The mechanical properties of fibrin for basic scientists and clinicians. Biophysical Chemistry. 112: 267-76. PMID 15572258 DOI: 10.1016/j.bpc.2004.07.029  0.64
2004 Tsurupa G, Veklich Y, Hantgan R, Belkin AM, Weisel JW, Medved L. Do the isolated fibrinogen alphaC-domains form ordered oligomers? Biophysical Chemistry. 112: 257-66. PMID 15572257 DOI: 10.1016/j.bpc.2004.07.028  0.64
2004 Marchi RC, Meyer MH, de Bosch NB, Arocha-Piñango CL, Weisel JW. A novel mutation (deletion of Aalpha-Asn 80) in an abnormal fibrinogen: fibrinogen Caracas VI. Consequences of disruption of the coiled coil for the polymerization of fibrin: peculiar clot structure and diminished stiffness of the clot. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 15: 559-67. PMID 15389122 DOI: 10.1097/00001721-200409000-00005  0.64
2004 Hantgan RR, Stahle MC, Connor JH, Lyles DS, Horita DA, Rocco M, Nagaswami C, Weisel JW, McLane MA. The disintegrin echistatin stabilizes integrin alphaIIbbeta3's open conformation and promotes its oligomerization. Journal of Molecular Biology. 342: 1625-36. PMID 15364586 DOI: 10.1016/j.jmb.2004.08.009  0.64
2004 Weisel JW, Collet JP. Packaging is important: accelerated thrombolysis with encapsulated plasminogen activators. Journal of Thrombosis and Haemostasis : Jth. 2: 1545-7. PMID 15333028 DOI: 10.1111/j.1538-7836.2004.00903.x  0.64
2004 Litvinov RI, Nagaswami C, Vilaire G, Shuman H, Bennett JS, Weisel JW. Functional and structural correlations of individual alphaIIbbeta3 molecules. Blood. 104: 3979-85. PMID 15319287 DOI: 10.1182/blood-2004-04-1411  0.64
2004 Weisel JW, Litvinov RI, Shuman H, Bennett JS. Additional considerations on measuring the binding strength of single ligand-receptor pairs on cells: reply to a rebuttal. Journal of Thrombosis and Haemostasis : Jth. 2: 1494-6. PMID 15304073 DOI: 10.1111/j.1538-7836.2004.00859.x  0.64
2004 Weisel JW. Cross-linked gamma-chains in a fibrin fibril are situated transversely between its strands. Journal of Thrombosis and Haemostasis : Jth. 2: 1467-9; discussion 1. PMID 15304056 DOI: 10.1111/j.1538-7836.2004.00873.x  0.64
2004 Marchi R, Meyer M, de Bosch N, Soria J, Arocha-Piñango CL, Weisel JW. Biophysical characterization of fibrinogen Caracas I with an Aalpha-chain truncation at Aalpha-466 Ser: identification of the mutation and biophysical characterization of properties of clots from plasma and purified fibrinogen. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 15: 285-93. PMID 15166913 DOI: 10.1097/00001721-200406000-00001  0.64
2004 Weisel JW. Cross-linked gamma-chains in fibrin fibrils bridge transversely between strands: no. Journal of Thrombosis and Haemostasis : Jth. 2: 394-9. PMID 15009453 DOI: 10.1111/j.1538-7933.2003.00621.x  0.64
2004 Weisel JW, Litvinov RI, Shuman H, Bennett JS. Measuring the binding strength of single ligand-receptor pairs on cells: rebuttal. Journal of Thrombosis and Haemostasis : Jth. 2: 372-4; author reply . PMID 14996025 DOI: 10.1111/j.1538-7836.2004.0584r.x  0.64
2004 Vadseth C, Souza JM, Thomson L, Seagraves A, Nagaswami C, Scheiner T, Torbet J, Vilaire G, Bennett JS, Murciano JC, Muzykantov V, Penn MS, Hazen SL, Weisel JW, Ischiropoulos H. Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species. The Journal of Biological Chemistry. 279: 8820-6. PMID 14681238 DOI: 10.1074/jbc.M306101200  0.64
2004 Collet JP, Nagaswami C, Farrell DH, Montalescot G, Weisel JW. Influence of gamma' fibrinogen splice variant on fibrin physical properties and fibrinolysis rate. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 382-6. PMID 14656741 DOI: 10.1161/01.ATV.0000109748.77727.3e  0.64
2003 Scheiner T, Jirousková M, Nagaswami C, Coller BS, Weisel JW. A monoclonal antibody to the fibrinogen gamma-chain alters fibrin clot structure and its properties by producing short, thin fibers arranged in bundles. Journal of Thrombosis and Haemostasis : Jth. 1: 2594-602. PMID 14675095 DOI: 10.1111/j.1538-7836.2003.00521.x  0.64
2003 Litvinov RI, Vilaire G, Shuman H, Bennett JS, Weisel JW. Quantitative analysis of platelet alpha v beta 3 binding to osteopontin using laser tweezers. The Journal of Biological Chemistry. 278: 51285-90. PMID 14534308 DOI: 10.1074/jbc.M304581200  0.64
2003 Paul BZ, Kim S, Dangelmaier C, Nagaswami C, Jin J, Hartwig JH, Weisel JW, Daniel JL, Kunapuli SP. Dynamic regulation of microtubule coils in ADP-induced platelet shape change by p160ROCK (Rho-kinase). Platelets. 14: 159-69. PMID 12850840 DOI: 10.1080/0953710031000092794  0.64
2003 Moen JL, Gorkun OV, Weisel JW, Lord ST. Recombinant BbetaArg14His fibrinogen implies participation of N-terminus of Bbeta chain in desA fibrin polymerization. Blood. 102: 2466-71. PMID 12805063 DOI: 10.1182/blood-2003-01-0204  0.64
2003 Myers JC, Li D, Amenta PS, Clark CC, Nagaswami C, Weisel JW. Type XIX collagen purified from human umbilical cord is characterized by multiple sharp kinks delineating collagenous subdomains and by intermolecular aggregates via globular, disulfide-linked, and heparin-binding amino termini. The Journal of Biological Chemistry. 278: 32047-57. PMID 12788917 DOI: 10.1074/jbc.M304629200  0.64
2003 Li R, Mitra N, Gratkowski H, Vilaire G, Litvinov R, Nagasami C, Weisel JW, Lear JD, DeGrado WF, Bennett JS. Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations. Science (New York, N.Y.). 300: 795-8. PMID 12730600 DOI: 10.1126/science.1079441  0.64
2003 Weisel JW, Shuman H, Litvinov RI. Protein-protein unbinding induced by force: single-molecule studies. Current Opinion in Structural Biology. 13: 227-35. PMID 12727517 DOI: 10.1016/S0959-440X(03)00039-3  0.64
2003 Lim BC, Ariëns RA, Carter AM, Weisel JW, Grant PJ. Genetic regulation of fibrin structure and function: complex gene-environment interactions may modulate vascular risk. Lancet. 361: 1424-31. PMID 12727396 DOI: 10.1016/S0140-6736(03)13135-2  0.64
2003 Standeven KF, Grant PJ, Carter AM, Scheiner T, Weisel JW, Ariëns RA. Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function. Circulation. 107: 2326-30. PMID 12707238 DOI: 10.1161/01.CIR.0000066690.89407.CE  0.64
2003 Collet JP, Lesty C, Montalescot G, Weisel JW. Dynamic changes of fibrin architecture during fibrin formation and intrinsic fibrinolysis of fibrin-rich clots. The Journal of Biological Chemistry. 278: 21331-5. PMID 12642590 DOI: 10.1074/jbc.M212734200  0.64
2003 Hantgan RR, Lyles DS, Mallett TC, Rocco M, Nagaswami C, Weisel JW. Ligand binding promotes the entropy-driven oligomerization of integrin alpha IIb beta 3. The Journal of Biological Chemistry. 278: 3417-26. PMID 12426312 DOI: 10.1074/jbc.M208869200  0.64
2002 Pieters M, Jerling JC, Weisel JW. Effect of freeze-drying, freezing and frozen storage of blood plasma on fibrin network characteristics. Thrombosis Research. 107: 263-9. PMID 12479888 DOI: 10.1016/S0049-3848(02)00344-4  0.64
2002 Cudic P, Behenna DC, Kranz JK, Kruger RG, Wand AJ, Veklich YI, Weisel JW, McCafferty DG. Functional analysis of the lipoglycodepsipeptide antibiotic ramoplanin. Chemistry & Biology. 9: 897-906. PMID 12204689 DOI: 10.1016/S1074-5521(02)00191-6  0.64
2002 Ariëns RA, Lai TS, Weisel JW, Greenberg CS, Grant PJ. Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood. 100: 743-54. PMID 12130481 DOI: 10.1182/blood.V100.3.743  0.64
2002 Hantgan RR, Stahle MC, Jerome WG, Nagaswami C, Weisel JW. Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure. Thrombosis and Haemostasis. 87: 910-7. PMID 12038797  0.64
2002 Litvinov RI, Shuman H, Bennett JS, Weisel JW. Binding strength and activation state of single fibrinogen-integrin pairs on living cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 7426-31. PMID 12032299 DOI: 10.1073/pnas.112194999  0.64
2002 Cudic P, Kranz JK, Behenna DC, Kruger RG, Tadesse H, Wand AJ, Veklich YI, Weisel JW, McCafferty DG. Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 7384-9. PMID 12032292 DOI: 10.1073/pnas.102192099  0.64
2002 Collet JP, Montalescot G, Lesty C, Weisel JW. A structural and dynamic investigation of the facilitating effect of glycoprotein IIb/IIIa inhibitors in dissolving platelet-rich clots. Circulation Research. 90: 428-34. PMID 11884372 DOI: 10.1161/hh0402.105095  0.64
2002 Standeven KF, Ariëns RA, Whitaker P, Ashcroft AE, Weisel JW, Grant PJ. The effect of dimethylbiguanide on thrombin activity, FXIII activation, fibrin polymerization, and fibrin clot formation. Diabetes. 51: 189-97. PMID 11756340  0.64
2001 Weisel JW, Nagaswami C, Woodhead JL, Higazi AA, Cain WJ, Marcovina SM, Koschinsky ML, Cines DB, Bdeir K. The structure of lipoprotein(a) and ligand-induced conformational changes. Biochemistry. 40: 10424-35. PMID 11523984 DOI: 10.1021/bi010556e  0.64
2001 Hantgan RR, Rocco M, Nagaswami C, Weisel JW. Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation. Protein Science : a Publication of the Protein Society. 10: 1614-26. PMID 11468358 DOI: 10.1110/ps.3001  0.64
2001 Mullin JL, Norfolk SE, Weisel JW, Lord ST. Clot lysis of variant recombinant fibrinogens confirms that fiber diameter is a major determinant of lysis rate. Annals of the New York Academy of Sciences. 936: 331-4. PMID 11460489  0.64
2001 Weisel JW, Medved L. The structure and function of the alpha C domains of fibrinogen. Annals of the New York Academy of Sciences. 936: 312-27. PMID 11460487  0.64
2001 Marchi R, Loyau S, Anglés-Cano E, Weisel JW. Structure and properties of clots from fibrinogen Bicêtre II (gamma 308 Asn-->Lys). Increased permeability due to larger pores, thicker fibers, and decreased rigidity. Annals of the New York Academy of Sciences. 936: 125-8. PMID 11460469  0.64
2000 Sugo T, Nakamikawa C, Yoshida N, Niwa K, Sameshima M, Mimuro J, Weisel JW, Nagita A, Matsuda M. End-linked homodimers in fibrinogen Osaka VI with a B beta-chain extension lead to fragile clot structure. Blood. 96: 3779-85. PMID 11090060  0.64
2000 Ariëns RA, Philippou H, Nagaswami C, Weisel JW, Lane DA, Grant PJ. The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure. Blood. 96: 988-95. PMID 10910914  0.64
2000 Collet JP, Park D, Lesty C, Soria J, Soria C, Montalescot G, Weisel JW. Influence of fibrin network conformation and fibrin fiber diameter on fibrinolysis speed: dynamic and structural approaches by confocal microscopy. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1354-61. PMID 10807754  0.64
2000 Shliom O, Huang M, Sachais B, Kuo A, Weisel JW, Nagaswami C, Nassar T, Bdeir K, Hiss E, Gawlak S, Harris S, Mazar A, Higazi AA. Novel interactions between urokinase and its receptor. The Journal of Biological Chemistry. 275: 24304-12. PMID 10801829 DOI: 10.1074/jbc.M002024200  0.64
2000 Hogan KA, Gorkun OV, Lounes KC, Coates AI, Weisel JW, Hantgan RR, Lord ST. Recombinant fibrinogen Vlissingen/Frankfurt IV. The deletion of residues 319 and 320 from the gamma chain of firbinogen alters calcium binding, fibrin polymerization, cross-linking, and platelet aggregation. The Journal of Biological Chemistry. 275: 17778-85. PMID 10748039 DOI: 10.1074/jbc.M001618200  0.64
2000 Murthy SN, Wilson JH, Lukas TJ, Veklich Y, Weisel JW, Lorand L. Transglutaminase-catalyzed crosslinking of the Aalpha and gamma constituent chains in fibrinogen. Proceedings of the National Academy of Sciences of the United States of America. 97: 44-8. PMID 10618368 DOI: 10.1073/pnas.97.1.44  0.64
2000 Ras A, Philippou H, Lane DA, Weisel JW, Grant PJ. The A-Val34Leu polymorphism accelerates activation of FXIII by thrombin and affects fibrin structure Fibrinolysis and Proteolysis. 14: 25.  0.64
2000 Murthy SNP, Wilson JH, Lukas TJ, Veklich Y, Weisel JW, Lorand L. Transglutaminase-catalyzed crosslinking of the Aa and y constituent chains in fibrinogen Proceedings of the National Academy of Sciences of the United States of America. 97: 44-48.  0.64
1999 Weisel JW, Veklich Y, Collet JP, Francis CW. Structural studies of fibrinolysis by electron and light microscopy. Thrombosis and Haemostasis. 82: 277-82. PMID 10605714  0.64
1999 Ryan EA, Mockros LF, Weisel JW, Lorand L. Structural origins of fibrin clot rheology. Biophysical Journal. 77: 2813-26. PMID 10545379 DOI: 10.1016/S0006-3495(99)77113-4  0.64
1999 Hantgan RR, Paumi C, Rocco M, Weisel JW. Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization. Biochemistry. 38: 14461-74. PMID 10545168 DOI: 10.1021/bi9907680  0.64
1998 Veklich Y, Francis CW, White J, Weisel JW. Structural studies of fibrinolysis by electron microscopy. Blood. 92: 4721-9. PMID 9845538  0.64
1998 Di Stasio E, Nagaswami C, Weisel JW, Di Cera E. Cl- regulates the structure of the fibrin clot. Biophysical Journal. 75: 1973-9. PMID 9746538 DOI: 10.1016/S0006-3495(98)77638-6  0.64
1998 Herbert CB, Nagaswami C, Bittner GD, Hubbell JA, Weisel JW. Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels. Journal of Biomedical Materials Research. 40: 551-9. PMID 9599031 DOI: 10.1002/(SICI)1097-4636(19980615)40:4<551::AID-JBM6>3.0.CO;2-E  0.64
1998 Veklich Y, Ang EK, Lorand L, Weisel JW. The complementary aggregation sites of fibrin investigated through examination of polymers of fibrinogen with fragment E. Proceedings of the National Academy of Sciences of the United States of America. 95: 1438-42. PMID 9465033 DOI: 10.1073/pnas.95.4.1438  0.64
1997 Gorkun OV, Veklich YI, Weisel JW, Lord ST. The conversion of fibrinogen to fibrin: recombinant fibrinogen typifies plasma fibrinogen. Blood. 89: 4407-14. PMID 9192765  0.64
1997 Chouhan VD, De La Cadena RA, Nagaswami C, Weisel JW, Kajani M, Rao AK. Simultaneous occurrence of human antibodies directed against fibrinogen, thrombin, and factor V following exposure to bovine thrombin: effects on blood coagulation, protein C activation and platelet function. Thrombosis and Haemostasis. 77: 343-9. PMID 9157594  0.64
1996 Weisel JW, Petersen IC. Plasminogen conformations. UkrainskiÄ­ BiokhimicheskiÄ­ Zhurnal. 68: 41. PMID 9226826  0.64
1996 Weisel JW. Fibrin clot architecture. UkrainskiÄ­ BiokhimicheskiÄ­ Zhurnal. 68: 29-30. PMID 9226817  0.64
1996 Weisel JW, Nagaswami C, Young TA, Light DR. The shape of thrombomodulin and interactions with thrombin as determined by electron microscopy. The Journal of Biological Chemistry. 271: 31485-90. PMID 8940162 DOI: 10.1074/jbc.271.49.31485  0.64
1996 Collet JP, Woodhead JL, Soria J, Soria C, Mirshahi M, Caen JP, Weisel JW. Fibrinogen Dusart: electron microscopy of molecules, fibers and clots, and viscoelastic properties of clots. Biophysical Journal. 70: 500-10. PMID 8770228 DOI: 10.1016/S0006-3495(96)79596-6  0.64
1995 Baradet TC, Haselgrove JC, Weisel JW. Three-dimensional reconstruction of fibrin clot networks from stereoscopic intermediate voltage electron microscope images and analysis of branching. Biophysical Journal. 68: 1551-60. PMID 7787040 DOI: 10.1016/S0006-3495(95)80327-9  0.64
1994 Weisel JW, Nagaswami C, Korsholm B, Petersen LC, Suenson E. Interactions of plasminogen with polymerizing fibrin and its derivatives, monitored with a photoaffinity cross-linker and electron microscopy. Journal of Molecular Biology. 235: 1117-35. PMID 8289311 DOI: 10.1006/jmbi.1994.1061  0.64
1994 Gorkun OV, Veklich YI, Medved LV, Henschen AH, Weisel JW. Role of the alpha C domains of fibrin in clot formation. Biochemistry. 33: 6986-97. PMID 8204632 DOI: 10.1021/bi00188a031  0.64
1994 Weisel JW, Nagaswami C, Woodhead JL, DeLa Cadena RA, Page JD, Colman RW. The shape of high molecular weight kininogen. Organization into structural domains, changes with activation, and interactions with prekallikrein, as determined by electron microscopy. The Journal of Biological Chemistry. 269: 10100-6. PMID 8144509  0.64
1993 Veklich YI, Gorkun OV, Medved LV, Nieuwenhuizen W, Weisel JW. Carboxyl-terminal portions of the alpha chains of fibrinogen and fibrin. Localization by electron microscopy and the effects of isolated alpha C fragments on polymerization. The Journal of Biological Chemistry. 268: 13577-85. PMID 8514790  0.64
1993 Weisel JW, Veklich Y, Gorkun O. The sequence of cleavage of fibrinopeptides from fibrinogen is important for protofibril formation and enhancement of lateral aggregation in fibrin clots. Journal of Molecular Biology. 232: 285-97. PMID 8331664 DOI: 10.1006/jmbi.1993.1382  0.64
1993 Weisel JW, Francis CW, Nagaswami C, Marder VJ. Determination of the topology of factor XIIIa-induced fibrin gamma-chain cross-links by electron microscopy of ligated fragments. The Journal of Biological Chemistry. 268: 26618-24. PMID 7902838  0.64
1993 Du X, Gu M, Weisel JW, Nagaswami C, Bennett JS, Bowditch R, Ginsberg MH. Long range propagation of conformational changes in integrin alpha IIb beta 3. The Journal of Biological Chemistry. 268: 23087-92. PMID 7693683  0.64
1992 Weisel JW, Nagaswami C, Vilaire G, Bennett JS. Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy. The Journal of Biological Chemistry. 267: 16637-43. PMID 1644841  0.64
1992 Weisel JW, Nagaswami C. Computer modeling of fibrin polymerization kinetics correlated with electron microscope and turbidity observations: clot structure and assembly are kinetically controlled. Biophysical Journal. 63: 111-28. PMID 1420861 DOI: 10.1016/S0006-3495(92)81594-1  0.64
1992 Abrams CS, Ruggeri ZM, Taub R, Hoxie JA, Nagaswami C, Weisel JW, Shattil SJ. Anti-idiotypic antibodies against an antibody to the platelet glycoprotein (GP) IIb-IIIa complex mimic GP IIb-IIIa by recognizing fibrinogen. The Journal of Biological Chemistry. 267: 2775-85. PMID 1370832  0.64
1992 Shattil SJ, Weisel JW, Kieber-Emmons T. Use of monoclonal antibodies to study the interaction between an integrin adhesion receptor, GP IIb-IIIa, and its physiological ligand, fibrinogen Immunomethods. 1: 53-63. DOI: 10.1016/S1058-6687(05)80028-2  0.64
1990 Sato H, Weisel JW. Polymerization of fibrinogen-derived fragment X and subsequent rearrangement of fibers. Thrombosis Research. 58: 205-12. PMID 2353337 DOI: 10.1016/0049-3848(90)90090-Y  0.64
1989 Husain SS, Weisel JW, Budzynski AZ. Interaction of fibrinogen and its derivatives with fibrin. The Journal of Biological Chemistry. 264: 11414-20. PMID 2738072  0.64
1989 Dang CV, Shin CK, Bell WR, Nagaswami C, Weisel JW. Fibrinogen sialic acid residues are low affinity calcium-binding sites that influence fibrin assembly. The Journal of Biological Chemistry. 264: 15104-8. PMID 2549051  0.64
1988 Langer BG, Weisel JW, Dinauer PA, Nagaswami C, Bell WR. Deglycosylation of fibrinogen accelerates polymerization and increases lateral aggregation of fibrin fibers. The Journal of Biological Chemistry. 263: 15056-63. PMID 3170575  0.64
1987 Weisel JW, Nagaswami C, Makowski L. Twisting of fibrin fibers limits their radial growth. Proceedings of the National Academy of Sciences of the United States of America. 84: 8991-5. PMID 3480524  0.64
1987 Weisel JW. Molecular symmetry and binding sites in fibrin assembly. Thrombosis Research. 48: 615-7. PMID 3441908  0.64
1987 Weisel JW, Papsun DM. Involvement of the COOH-terminal portion of the alpha-chain of fibrin in the branching of fibers to form a clot. Thrombosis Research. 47: 155-63. PMID 2958957 DOI: 10.1016/0049-3848(87)90372-0  0.64
1986 Weisel JW. Fibrin assembly. Lateral aggregation and the role of the two pairs of fibrinopeptides. Biophysical Journal. 50: 1079-93. PMID 3801570 DOI: 10.1016/S0006-3495(86)83552-4  0.64
1986 Weisel JW. The electron microscope band pattern of human fibrin: various stains, lateral order, and carbohydrate localization. Journal of Ultrastructure and Molecular Structure Research. 96: 176-88. PMID 2445864 DOI: 10.1016/0889-1605(86)90019-4  0.64
1985 Weisel JW, Stauffacher CV, Bullitt E, Cohen C. A model for fibrinogen: domains and sequence. Science (New York, N.Y.). 230: 1388-91. PMID 4071058  0.64
1983 Wangh LJ, Holland LJ, Spolski RJ, Aprison BS, Weisel JW. Xenopus fibrinogen. Characterization of subunits and hormonal regulation of biosynthesis. The Journal of Biological Chemistry. 258: 4599-605. PMID 6833268  0.64
1983 Weisel JW, Phillips GN, Cohen C. The structure of fibrinogen and fibrin: II. Architecture of the fibrin clot. Annals of the New York Academy of Sciences. 408: 367-79. PMID 6575694  0.64
1983 Cohen C, Weisel JW, Phillips GN, Stauffacher CV, Fillers JP, Daub E. The structure of fibrinogen and fibrin: I. Electron microscopy and X-ray crystallography of fibrinogen. Annals of the New York Academy of Sciences. 408: 194-213. PMID 6575684  0.64
1983 Holland LJ, Weisel JW, Wangh LJ. Xenopus fibrinogen: Characterization of subunits, post-translational modifications, in vitro translantion, and glucocorticoid-regulated synthesis Annals of the New York Academy of Sciences. 649-650.  0.64
1981 Weisel JW, Phillips GN, Cohen C. A model from electron microscopy for the molecular structure of fibrinogen and fibrin. Nature. 289: 263-7. PMID 7453823 DOI: 10.1038/289263a0  0.64
1981 Wangh LJ, Holland LJ, Weisel JW. Isolation, characterization, and steroid hormone regulation of synthesis of fibrinogen from Xenopus laevis Thrombosis and Haemostasis. 46: No. 0752.  0.64
1980 Weisel JW, Cohen C, Tooney NM, Kaplan I, Amrani D. Segments from modified human fibrinogen. Journal of Molecular Biology. 143: 329-34. PMID 7218358 DOI: 10.1016/0022-2836(80)90194-1  0.64
1978 Weisel JW, Warren SG, Cohen C. Crystals of modified fibrinogen: size, shape and packing of molecules. Journal of Molecular Biology. 126: 159-83. PMID 739546 DOI: 10.1016/0022-2836(78)90357-1  0.64
1975 Weisel JW. Paramyosin segments: molecular orientation and interactions in invertebrate muscle thick filaments. Journal of Molecular Biology. 98: 675-81. PMID 1195406 DOI: 10.1016/S0022-2836(75)80003-9  0.64
1975 Weisel JW, Szent-Györgyi AG. The coiled-coil structure: identity of the two chains of Mercenaria paramyosin. Journal of Molecular Biology. 98: 665-73. PMID 1195405 DOI: 10.1016/S0022-2836(75)80002-7  0.64
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