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William A. Pastor, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Biochemistry
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31/58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Graham-Paquin AL, Saini D, Sirois J, Hossain I, Katz MS, Zhuang QK, Kwon SY, Yamanaka Y, Bourque G, Bouchard M, Pastor WA. ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development. Nucleic Acids Research. 51: 7314-7329. PMID 37395395 DOI: 10.1093/nar/gkad540  0.445
2022 Pastor WA, Kwon SY. Distinctive aspects of the placental epigenome and theories as to how they arise. Cellular and Molecular Life Sciences : Cmls. 79: 569. PMID 36287261 DOI: 10.1007/s00018-022-04568-9  0.316
2022 Chen H, Hu B, Horth C, Bareke E, Rosenbaum P, Kwon SY, Sirois J, Weinberg DN, Robison FM, Garcia BA, Lu C, Pastor WA, Majewski J. H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells. Genome Research. PMID 35396277 DOI: 10.1101/gr.276383.121  0.398
2021 Azevedo Portilho N, Saini D, Hossain I, Sirois J, Moraes C, Pastor WA. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. Epigenetics & Chromatin. 14: 56. PMID 34906184 DOI: 10.1186/s13072-021-00429-0  0.463
2020 Liu X, Ouyang JF, Rossello FJ, Tan JP, Davidson KC, Valdes DS, Schröder J, Sun YBY, Chen J, Knaupp AS, Sun G, Chy HS, Huang Z, Pflueger J, Firas J, ... ... Pastor WA, et al. Reprogramming roadmap reveals route to human induced trophoblast stem cells. Nature. PMID 32939092 DOI: 10.1038/S41586-020-2734-6  0.409
2018 Chen D, Liu W, Zimmerman J, Pastor WA, Kim R, Hosohama L, Ho J, Aslanyan M, Gell JJ, Jacobsen SE, Clark AT. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Reports. 25: 3591-3602.e5. PMID 30590035 DOI: 10.1016/J.Celrep.2018.12.011  0.436
2018 Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen SE, Clark AT. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nature Cell Biology. 20: 553-564. PMID 29695788 DOI: 10.1038/S41556-018-0089-0  0.407
2017 Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M. Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 6. PMID 28858608 DOI: 10.7554/Elife.30948  0.499
2017 Tsagaratou A, González-Avalos E, Rautio S, Scott-Browne JP, Togher S, Pastor WA, Rothenberg EV, Chavez L, Lähdesmäki H, Rao A. TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells. Nature Immunology. 18: 45-53. PMID 27869820 DOI: 10.1038/Ni.3630  0.606
2016 Li X, Yue X, Pastor WA, Lin L, Georges R, Chavez L, Evans SM, Rao A. Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930333 DOI: 10.1073/Pnas.1617802113  0.573
2016 Li S, Yen L, Pastor WA, Johnston JB, Du J, Shew CJ, Liu W, Ho J, Stender B, Clark AT, Burlingame AL, Daxinger L, Patel DJ, Jacobsen SE. Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. Proceedings of the National Academy of Sciences of the United States of America. 113: E5108-16. PMID 27528681 DOI: 10.1073/Pnas.1609709113  0.344
2016 Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen SE. Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes. Plos Genetics. 12: e1005998. PMID 27171361 DOI: 10.1371/Journal.Pgen.1005998  0.54
2016 Yue X, Trifari S, Äijö T, Tsagaratou A, Pastor WA, Zepeda-Martínez JA, Lio CJ, Li X, Huang Y, Vijayanand P, Lähdesmäki H, Rao A. Control of Foxp3 stability through modulation of TET activity. The Journal of Experimental Medicine. PMID 26903244 DOI: 10.1084/Jem.20151438  0.596
2016 Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 18: 323-329. PMID 26853856 DOI: 10.1016/J.Stem.2016.01.019  0.395
2015 Manakov SA, Pezic D, Marinov GK, Pastor WA, Sachidanandam R, Aravin AA. MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation. Cell Reports. 12: 1234-43. PMID 26279574 DOI: 10.1016/J.Celrep.2015.07.036  0.58
2015 Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A. Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E4236-45. PMID 26199412 DOI: 10.1073/Pnas.1510510112  0.607
2015 Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M. In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 4: e06205. PMID 25848745 DOI: 10.7554/Elife.06205  0.529
2015 Ko M, An J, Pastor WA, Koralov SB, Rajewsky K, Rao A. TET proteins and 5-methylcytosine oxidation in hematological cancers. Immunological Reviews. 263: 6-21. PMID 25510268 DOI: 10.1111/Imr.12239  0.665
2014 Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE. MORC1 represses transposable elements in the mouse male germline. Nature Communications. 5: 5795. PMID 25503965 DOI: 10.1038/Ncomms6795  0.527
2014 Chavez L, Huang Y, Luong K, Agarwal S, Iyer LM, Pastor WA, Hench VK, Frazier-Bowers SA, Korol E, Liu S, Tahiliani M, Wang Y, Clark TA, Korlach J, Pukkila PJ, et al. Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea. Proceedings of the National Academy of Sciences of the United States of America. 111: E5149-58. PMID 25406324 DOI: 10.1073/Pnas.1419513111  0.743
2014 Moissiard G, Bischof S, Husmann D, Pastor WA, Hale CJ, Yen L, Stroud H, Papikian A, Vashisht AA, Wohlschlegel JA, Jacobsen SE. Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Proceedings of the National Academy of Sciences of the United States of America. 111: 7474-9. PMID 24799676 DOI: 10.1073/Pnas.1406611111  0.557
2014 Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1361-6. PMID 24474761 DOI: 10.1073/Pnas.1322921111  0.679
2013 Pastor WA, Aravind L, Rao A. TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nature Reviews. Molecular Cell Biology. 14: 341-56. PMID 23698584 DOI: 10.1038/Nrm3589  0.667
2013 Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A. Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature. 497: 122-6. PMID 23563267 DOI: 10.1038/Nature12052  0.649
2012 Pastor WA, Huang Y, Henderson HR, Agarwal S, Rao A. The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1909-17. PMID 23018194 DOI: 10.1038/nprot.2012.104  0.751
2012 Huang Y, Pastor WA, Zepeda-Martínez JA, Rao A. The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1897-908. PMID 23018193 DOI: 10.1038/Nprot.2012.103  0.654
2011 Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 473: 394-7. PMID 21552279 DOI: 10.1038/Nature10102  0.763
2011 Rao A, Ko M, Pastor W, Huang Y. TET2: Mechanism and Functional Consequences of Hydroxymethylation Blood. 118: SCI-32-SCI-32. DOI: 10.1182/Blood.V118.21.Sci-32.Sci-32  0.653
2010 Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. Plos One. 5: e8888. PMID 20126651 DOI: 10.1371/Journal.Pone.0008888  0.76
2009 Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (New York, N.Y.). 324: 930-5. PMID 19372391 DOI: 10.1126/Science.1170116  0.764
2008 Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart JW, Shi Y, Kremmer E, Rao A, Heissmeyer V. Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing. Nature Structural & Molecular Biology. 15: 523-30. PMID 18438418 DOI: 10.1038/Nsmb.1417  0.711
Low-probability matches (unlikely to be authored by this person)
2021 Desai VP, Chouaref J, Wu H, Pastor WA, Kan RL, Oey HM, Li Z, Ho J, Vonk KKD, San Leon Granado D, Christopher MA, Clark AT, Jacobsen SE, Daxinger L. The role of MORC3 in silencing transposable elements in mouse embryonic stem cells. Epigenetics & Chromatin. 14: 49. PMID 34706774 DOI: 10.1186/s13072-021-00420-9  0.298
2021 Guo Y, Xue Z, Yuan R, Li JJ, Pastor WA, Liu W. RAD: a web application to identify region associated differentially expressed genes. Bioinformatics (Oxford, England). PMID 33532827 DOI: 10.1093/bioinformatics/btab075  0.284
2021 Cai T, Cinkornpumin JK, Yu Z, Villarreal OD, Pastor WA, Richard S. Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects. Cell Reports. 36: 109337. PMID 34260915 DOI: 10.1016/j.celrep.2021.109337  0.274
2020 Cinkornpumin JK, Kwon SY, Guo Y, Hossain I, Sirois J, Russett CS, Tseng HW, Okae H, Arima T, Duchaine TF, Liu W, Pastor WA. Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome. Stem Cell Reports. PMID 32619492 DOI: 10.1016/j.stemcr.2020.06.003  0.264
2022 Cinkornpumin JK, Hossain I, Pastor WA. Mapping Chromatin Accessibility in Human Naïve Pluripotent Stem Cells Using ATAC-Seq. Methods in Molecular Biology (Clifton, N.J.). 2416: 201-211. PMID 34870838 DOI: 10.1007/978-1-0716-1908-7_13  0.264
2015 Bhansali P, Wiedermann BL, Pastor W, McMillan J, Shah N. Management of Hospitalized Febrile Neonates Without CSF Analysis: A Study of US Pediatric Hospitals. Hospital Pediatrics. 5: 528-33. PMID 26427921 DOI: 10.1542/Hpeds.2014-0175  0.211
2015 Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE. Erratum: MORC1 represses transposable elements in the mouse male germline. Nature Communications. 6: 7604. PMID 26159654 DOI: 10.1038/Ncomms8604  0.2
2011 Pillai D, Song X, Pastor W, Ottolini M, Powell D, Wiedermann BL, DeBiasi RL. Implementation and impact of a consensus diagnostic and management algorithm for complicated pneumonia in children. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 59: 1221-7. PMID 21941212 DOI: 10.2310/Jim.0B013E318231Db4D  0.193
2007 Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL. Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 178: 5652-8. PMID 17442948 DOI: 10.4049/Jimmunol.178.9.5652  0.164
2019 Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, ... ... Pastor WA, et al. SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nature Communications. 10: 557. PMID 30718506 DOI: 10.1038/S41467-019-08380-1  0.162
2024 Penalva YCM, Paschkowsky S, Yang J, Recinto SJ, Cinkorpumin J, Xiao B, Nitu A, Wu H, Munter HM, Michalski B, Fahnestock M, Pastor W, Bennett DA, Munter LM. Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model. Biorxiv : the Preprint Server For Biology. PMID 38464180 DOI: 10.1101/2024.02.22.579698  0.128
2022 Parameshwar PK, Sagrillo-Fagundes L, Azevedo Portilho N, Pastor WA, Vaillancourt C, Moraes C. Engineered models for placental toxicology: Emerging approaches based on tissue decellularization. Reproductive Toxicology (Elmsford, N.Y.). 112: 148-159. PMID 35840119 DOI: 10.1016/j.reprotox.2022.07.003  0.108
2022 Rahbani JF, Scholtes C, Lagarde DM, Hussain MF, Roesler A, Dykstra CB, Bunk J, Samborska B, O'Brien SL, Tripp E, Pacis A, Angueira AR, Johansen OS, Cinkornpumin J, Hossain I, ... ... Pastor WA, et al. ADRA1A-Gα signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism. PMID 36344764 DOI: 10.1038/s42255-022-00667-w  0.107
2015 Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Azim Surani M, Koralov SB, Kalantry S, Chavez L, Rao A. Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis Proceedings of the National Academy of Sciences of the United States of America. 112: E4236-E4245. DOI: 10.1073/pnas.1510510112  0.091
2018 Ramakrishnan KV, Zurakowski D, Pastor W, Jonas RA, Sinha P. Symptomatic Tetralogy of Fallot in Young Infants: Primary Repair or Shunt-Pediatric Health Information System Database Analysis. World Journal For Pediatric & Congenital Heart Surgery. 9: 539-545. PMID 30157746 DOI: 10.1177/2150135118780615  0.034
2019 Ghelani SJ, Pastor W, Parikh K. Demographic and treatment variability of refractory kawasaki disease: a multicenter analysis from 2005 to 2009. Hospital Pediatrics. 2: 71-6. PMID 24510952 DOI: 10.1542/hpeds.2011-00112  0.032
2006 Chavanu K, Newman K, Fried W, Daymont M, Slonim A, Koza E, Pastor W, Robinson NC, Holbrook P. Transforming a payer-provider relationship from conflict to collaboration. Journal For Healthcare Quality : Official Publication of the National Association For Healthcare Quality. 28: 4-11. PMID 17518009 DOI: 10.1111/J.1945-1474.2006.Tb00606.X  0.031
2011 Hickey PW, Cape KE, Masuoka P, Campos JM, Pastor W, Wong EC, Singh N. A local, regional, and national assessment of pediatric malaria in the United States. Journal of Travel Medicine. 18: 153-60. PMID 21539653 DOI: 10.1111/j.1708-8305.2011.00514.x  0.028
2016 Punnoose AR, Kaltman JR, Pastor W, McCarter R, He J, Spurney CF. Cardiac Disease Burden and Risk of Mortality in Hospitalized Muscular Dystrophy Patients. Pediatric Cardiology. PMID 27314489 DOI: 10.1007/s00246-016-1432-5  0.024
2015 Orgel E, Ji L, Pastor W, Schore RJ. Infectious morbidity by catheter type in neutropenic children with cancer. The Pediatric Infectious Disease Journal. 33: 263-6. PMID 24263218 DOI: 10.1097/INF.0000000000000060  0.024
2013 Vanderver A, Hussey H, Schmidt JL, Pastor W, Hoffman HJ. Relative incidence of inherited white matter disorders in childhood to acquired pediatric demyelinating disorders. Seminars in Pediatric Neurology. 19: 219-23. PMID 23245555 DOI: 10.1016/j.spen.2012.10.001  0.021
2011 Siegel D, Song X, Klontz K, Pastor W, Singh N. Epidemiology of childhood tuberculosis: use and evaluation of the pediatric health information system to assess local and national incidence. The Pediatric Infectious Disease Journal. 30: 428-30. PMID 21346685 DOI: 10.1097/Inf.0B013E318211581E  0.021
2012 Ghelani SJ, Spaeder MC, Pastor W, Spurney CF, Klugman D. Demographics, trends, and outcomes in pediatric acute myocarditis in the United States, 2006 to 2011. Circulation. Cardiovascular Quality and Outcomes. 5: 622-7. PMID 22828827 DOI: 10.1161/CIRCOUTCOMES.112.965749  0.011
2013 Klugman D, Berger JT, Spaeder MC, Wright A, Pastor W, Stockwell DC. Acute harm: unplanned extubations and cardiopulmonary resuscitation in children and neonates. Intensive Care Medicine. 39: 1333-4. PMID 23636827 DOI: 10.1007/s00134-013-2932-x  0.011
1988 Pastor WA. AIDS patient care: a social responsibility Health Progress (Saint Louis, Mo.). 69. PMID 10286243  0.01
2018 Jichlinski A, Badolato G, Pastor W, Goyal MK. HIV and Syphilis Screening Among Adolescents Diagnosed With Pelvic Inflammatory Disease. Pediatrics. PMID 30042114 DOI: 10.1542/peds.2017-4061  0.01
2016 Roddy DJ, Spaeder MC, Pastor W, Stockwell DC, Klugman D. Unplanned Extubations in Children: Impact on Hospital Cost and Length of Stay. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 572-5. PMID 25901542 DOI: 10.1097/PCC.0000000000000406  0.01
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