Dario A. Vignali - Publications

Affiliations: 
Microbial Pathogenesis, Immunology, and Inflammation University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Cell Biology, Molecular Biology

73/133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chuckran CA, Liu C, Bruno TC, Workman CJ, Vignali DA. Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy. Journal For Immunotherapy of Cancer. 8. PMID 32675311 DOI: 10.1136/Jitc-2020-000967  0.48
2019 Liu B, Hood JD, Kolawole EM, Woodruff DM, Vignali DA, Bettini M, Evavold BD. A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery. Diabetes. PMID 31806623 DOI: 10.2337/Db19-0399  0.371
2016 Turnis ME, Sawant DV, Szymczak-Workman AL, Andrews LP, Delgoffe GM, Yano H, Beres AJ, Vogel P, Workman CJ, Vignali DA. Interleukin-35 Limits Anti-Tumor Immunity. Immunity. 44: 316-29. PMID 26872697 DOI: 10.1016/J.Immuni.2016.01.013  0.377
2016 Liu C, Workman CJ, Vignali DA. Targeting Regulatory T Cells in Tumors. The Febs Journal. PMID 26787424 DOI: 10.1111/febs.13656  0.339
2016 Overacre AE, Vignali DA. T(reg) stability: to be or not to be. Current Opinion in Immunology. 39: 39-43. PMID 26774863 DOI: 10.1016/j.coi.2015.12.009  0.32
2015 Turnis ME, Andrews LP, Vignali DA. Inhibitory receptors as targets for cancer immunotherapy. European Journal of Immunology. 45: 1892-905. PMID 26018646 DOI: 10.1002/eji.201344413  0.35
2014 Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, et al. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science (New York, N.Y.). 346: 363-8. PMID 25324392 DOI: 10.1126/science.1259077  0.384
2014 Jha V, Workman CJ, McGaha TL, Li L, Vas J, Vignali DA, Monestier M. Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity. Plos One. 9: e104484. PMID 25122007 DOI: 10.1371/Journal.Pone.0104484  0.321
2014 Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer MP, Zhang H, Hogquist KA, Evavold BD, Vignali DA. TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. Journal of Immunology (Baltimore, Md. : 1950). 193: 571-9. PMID 24943217 DOI: 10.4049/Jimmunol.1400043  0.398
2014 Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA. Membrane association of the CD3ε signaling domain is required for optimal T cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 193: 258-67. PMID 24899501 DOI: 10.4049/Jimmunol.1400322  0.366
2014 Sawant DV, Vignali DA. Once a Treg, always a Treg? Immunological Reviews. 259: 173-91. PMID 24712466 DOI: 10.1111/Imr.12173  0.303
2014 Hoseini SS, Hapke M, Herbst J, Wedekind D, Baumann R, Krueger A, Heinz N, Schiedlmeier B, Vignali D, van den Brink MR, Schambach A, Blazar BR, Sauer MG. Timely Controlled T Cell Receptor Expression of Genetically Engineered Precursor T Cells Requires Early Transgene Induction for Leukemia Control after Hematopoietic Stem Cell Transplantation Blood. 124: 657-657. DOI: 10.1182/Blood.V124.21.657.657  0.422
2013 Shi LZ, Kalupahana NS, Turnis ME, Neale G, Hock H, Vignali DA, Chi H. Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E3198-205. PMID 23918371 DOI: 10.1073/Pnas.1300950110  0.425
2013 Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA. Retraction. Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. Journal of Immunology (Baltimore, Md. : 1950). 191: 2018. PMID 23913974 DOI: 10.4049/Jimmunol.1390040  0.361
2013 Delgoffe GM, Woo SR, Turnis ME, Gravano DM, Guy C, Overacre AE, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature. 501: 252-6. PMID 23913274 DOI: 10.1038/Nature12428  0.345
2013 Sakaguchi S, Vignali DA, Rudensky AY, Niec RE, Waldmann H. The plasticity and stability of regulatory T cells. Nature Reviews. Immunology. 13: 461-7. PMID 23681097 DOI: 10.1038/Nri3464  0.419
2013 Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF. Regulatory T cells: recommendations to simplify the nomenclature. Nature Immunology. 14: 307-8. PMID 23507634 DOI: 10.1038/Ni.2554  0.4
2013 Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, Zhang H, Huppa JB, Tsai YH, Lobry C, Xie J, Dempsey PJ, Crawford HC, Aifantis I, Davis MM, ... Vignali DA, et al. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nature Immunology. 14: 262-70. PMID 23377202 DOI: 10.1038/Ni.2538  0.326
2012 Delgoffe GM, Bettini ML, Vignali DA. Identity crisis: it's not just Foxp3 anymore. Immunity. 37: 759-61. PMID 23159220 DOI: 10.1016/J.Immuni.2012.10.012  0.34
2012 Olson BM, Jankowska-Gan E, Becker JT, Vignali DA, Burlingham WJ, McNeel DG. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. Journal of Immunology (Baltimore, Md. : 1950). 189: 5590-601. PMID 23152566 DOI: 10.4049/Jimmunol.1201744  0.381
2012 Do JS, Valujskikh A, Vignali DA, Fairchild RL, Min B. Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 12698-703. PMID 22802622 DOI: 10.1073/Pnas.1207219109  0.397
2012 Delmastro MM, Styche AJ, Trucco MM, Workman CJ, Vignali DA, Piganelli JD. Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind. Diabetes. 61: 1760-8. PMID 22586584 DOI: 10.2337/db11-1591  0.366
2012 Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA. Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity. 36: 717-30. PMID 22579476 DOI: 10.1016/J.Immuni.2012.03.020  0.335
2012 Bettini ML, Bettini M, Vignali DA. T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice. Immunology. 136: 265-72. PMID 22348644 DOI: 10.1111/J.1365-2567.2012.03574.X  0.405
2012 Gravano DM, Vignali DA. The battle against immunopathology: infectious tolerance mediated by regulatory T cells. Cellular and Molecular Life Sciences : Cmls. 69: 1997-2008. PMID 22205213 DOI: 10.1007/s00018-011-0907-z  0.394
2012 Dixon K, Kooij Sd, Schlagwein N, Vignali DA, Kooten Cv. O038 Role of human tolerogenic dendritic cell derived IL-35 in regulating T cell responses Cytokine. 59: 515-515. DOI: 10.1016/J.Cyto.2012.06.075  0.346
2011 Pillai MR, Collison LW, Wang X, Finkelstein D, Rehg JE, Boyd K, Szymczak-Workman AL, Doggett T, Griffith TS, Ferguson TA, Vignali DA. The plasticity of regulatory T cell function. Journal of Immunology (Baltimore, Md. : 1950). 187: 4987-97. PMID 22013112 DOI: 10.4049/Jimmunol.1102173  0.341
2011 Szymczak-Workman AL, Delgoffe GM, Green DR, Vignali DA. Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways. Journal of Immunology (Baltimore, Md. : 1950). 187: 4416-20. PMID 21949016 DOI: 10.4049/Jimmunol.1100548  0.343
2011 Day EB, Guillonneau C, Gras S, La Gruta NL, Vignali DA, Doherty PC, Purcell AW, Rossjohn J, Turner SJ. Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 9536-41. PMID 21606376 DOI: 10.1073/Pnas.1106851108  0.3
2011 Viret C, Leung-Theung-Long S, Serre L, Lamare C, Vignali DA, Malissen B, Carrier A, Guerder S. Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice. The Journal of Clinical Investigation. 121: 1810-21. PMID 21505262 DOI: 10.1172/JCI43314  0.376
2011 Lucas CL, Workman CJ, Beyaz S, LoCascio S, Zhao G, Vignali DA, Sykes M. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood. 117: 5532-40. PMID 21422469 DOI: 10.1182/Blood-2010-11-318675  0.359
2011 Workman CJ, Collison LW, Bettini M, Pillai MR, Rehg JE, Vignali DA. In vivo Treg suppression assays. Methods in Molecular Biology (Clifton, N.J.). 707: 119-56. PMID 21287333 DOI: 10.1007/978-1-61737-979-6_9  0.332
2011 Koestner W, Hapke M, Herbst J, Klein C, Welte K, Fruehauf J, Flatley A, Vignali DA, Hardtke-Wolenski M, Jaeckel E, Blazar BR, Sauer MG. PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells. Blood. 117: 1030-41. PMID 21063028 DOI: 10.1182/Blood-2010-04-283119  0.448
2011 Goldberg MV, Woo S, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Vogel P, Grosso JF, Netto G, Chaux A, Smeltzer M, Workman CJ, Pardoll DM, Korman AJ, Vignali DA, et al. Abstract LB-251: The checkpoint molecules LAG-3 and PD-1 synergize to maintain tolerance to tumors Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-251  0.321
2010 Collison LW, Chaturvedi V, Henderson AL, Giacomin PR, Guy C, Bankoti J, Finkelstein D, Forbes K, Workman CJ, Brown SA, Rehg JE, Jones ML, Ni HT, Artis D, Turk MJ, ... Vignali DA, et al. IL-35-mediated induction of a potent regulatory T cell population. Nature Immunology. 11: 1093-101. PMID 20953201 DOI: 10.1038/Ni.1952  0.367
2010 Woo SR, Li N, Bruno TC, Forbes K, Brown S, Workman C, Drake CG, Vignali DA. Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4. European Journal of Immunology. 40: 1768-77. PMID 20391435 DOI: 10.1002/Eji.200939874  0.332
2010 Burton AR, Baquet Z, Eisenbarth GS, Tisch R, Smeyne R, Workman CJ, Vignali DA. Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 4863-70. PMID 20348424 DOI: 10.4049/Jimmunol.0903728  0.376
2010 Wang H, Holst J, Woo SR, Guy C, Bettini M, Wang Y, Shafer A, Naramura M, Mingueneau M, Dragone LL, Hayes SM, Malissen B, Band H, Vignali DA. Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development. The Embo Journal. 29: 1285-98. PMID 20150895 DOI: 10.1038/Emboj.2010.10  0.373
2010 Bettini ML, Vignali DA. Development of thymically derived natural regulatory T cells. Annals of the New York Academy of Sciences. 1183: 1-12. PMID 20146704 DOI: 10.1111/J.1749-6632.2009.05129.X  0.318
2009 Guy CS, Vignali DA. Organization of proximal signal initiation at the TCR:CD3 complex. Immunological Reviews. 232: 7-21. PMID 19909352 DOI: 10.1111/j.1600-065X.2009.00843.x  0.352
2009 Bettini M, Vignali DA. Regulatory T cells and inhibitory cytokines in autoimmunity. Current Opinion in Immunology. 21: 612-8. PMID 19854631 DOI: 10.1016/j.coi.2009.09.011  0.395
2009 Lennon GP, Bettini M, Burton AR, Vincent E, Arnold PY, Santamaria P, Vignali DA. T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity. 31: 643-53. PMID 19818656 DOI: 10.1016/j.immuni.2009.07.008  0.409
2009 Grosso JF, Goldberg MV, Getnet D, Bruno TC, Yen HR, Pyle KJ, Hipkiss E, Vignali DA, Pardoll DM, Drake CG. Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6659-69. PMID 19454660 DOI: 10.4049/Jimmunol.0804211  0.345
2009 Collison LW, Pillai MR, Chaturvedi V, Vignali DA. Regulatory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 182: 6121-8. PMID 19414764 DOI: 10.4049/Jimmunol.0803646  0.382
2009 Workman CJ, Szymczak-Workman AL, Collison LW, Pillai MR, Vignali DA. The development and function of regulatory T cells. Cellular and Molecular Life Sciences : Cmls. 66: 2603-22. PMID 19390784 DOI: 10.1007/S00018-009-0026-2  0.431
2009 Szymczak-Workman AL, Workman CJ, Vignali DA. Cutting edge: regulatory T cells do not require stimulation through their TCR to suppress. Journal of Immunology (Baltimore, Md. : 1950). 182: 5188-92. PMID 19380762 DOI: 10.4049/jimmunol.0803123  0.389
2009 Workman CJ, Wang Y, El Kasmi KC, Pardoll DM, Murray PJ, Drake CG, Vignali DA. LAG-3 regulates plasmacytoid dendritic cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 182: 1885-91. PMID 19201841 DOI: 10.4049/Jimmunol.0800185  0.431
2009 Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, Betts MR, Freeman GJ, Vignali DA, Wherry EJ. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nature Immunology. 10: 29-37. PMID 19043418 DOI: 10.1038/Ni.1679  0.389
2009 Nakayama M, Castoe T, Jasinski J, He X, Johnson K, Haskins K, Pollock D, Vignali D, Eisenbarth G. OR.66. Pathogenic T Cell Receptor Valpha Germline Sequence Targeting Primary Peptide Insulin B:9-23 Clinical Immunology. 131: S28. DOI: 10.1016/J.Clim.2009.03.078  0.333
2008 Vogtenhuber C, O'Shaughnessy MJ, Vignali DA, Blazar BR. Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo. Journal of Immunology (Baltimore, Md. : 1950). 181: 8767-75. PMID 19050298 DOI: 10.4049/Jimmunol.181.12.8767  0.326
2008 Vignali DA, Collison LW, Workman CJ. How regulatory T cells work. Nature Reviews. Immunology. 8: 523-32. PMID 18566595 DOI: 10.1038/Nri2343  0.406
2008 Tailor P, Tsai S, Shameli A, Serra P, Wang J, Robbins S, Nagata M, Szymczak-Workman AL, Vignali DA, Santamaria P. The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling. Journal of Immunology (Baltimore, Md. : 1950). 181: 243-55. PMID 18566390 DOI: 10.4049/Jimmunol.181.1.243  0.337
2008 Holst J, Wang H, Eder KD, Workman CJ, Boyd KL, Baquet Z, Singh H, Forbes K, Chruscinski A, Smeyne R, van Oers NS, Utz PJ, Vignali DA. Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nature Immunology. 9: 658-66. PMID 18469818 DOI: 10.1038/Ni.1611  0.35
2008 Chaparro RJ, Burton AR, Serreze DV, Vignali DA, DiLorenzo TP. Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. Journal of Immunological Methods. 335: 106-15. PMID 18439618 DOI: 10.1016/J.Jim.2008.03.007  0.427
2008 Liang B, Workman C, Lee J, Chew C, Dale BM, Colonna L, Flores M, Li N, Schweighoffer E, Greenberg S, Tybulewicz V, Vignali D, Clynes R. Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. Journal of Immunology (Baltimore, Md. : 1950). 180: 5916-26. PMID 18424711 DOI: 10.4049/Jimmunol.180.9.5916  0.405
2008 Vignali D. How many mechanisms do regulatory T cells need? European Journal of Immunology. 38: 908-11. PMID 18395857 DOI: 10.1002/eji.200738114  0.341
2008 Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes. 57: 1321-30. PMID 18299317 DOI: 10.2337/Db07-1129  0.37
2008 Chaparro R, Burton A, Serreze D, Vignali D, DiLorenzo T. Sa.67. Rapid Identification of MHC Class I-restricted Antigens Relevant to Autoimmune Diabetes Using Retrogenic T Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.288  0.388
2008 Vignali D. Cover Picture: How many mechanisms do regulatory T cells need? – Eur. J. Immunol. 4/2008 European Journal of Immunology. 38. DOI: 10.1002/Eji.200890013  0.343
2007 Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature. 450: 566-9. PMID 18033300 DOI: 10.1038/Nature06306  0.412
2007 Li N, Wang Y, Forbes K, Vignali KM, Heale BS, Saftig P, Hartmann D, Black RA, Rossi JJ, Blobel CP, Dempsey PJ, Workman CJ, Vignali DA. Metalloproteases regulate T-cell proliferation and effector function via LAG-3. The Embo Journal. 26: 494-504. PMID 17245433 DOI: 10.1038/Sj.Emboj.7601520  0.422
2006 Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA. Generation of T-cell receptor retrogenic mice. Nature Protocols. 1: 406-17. PMID 17406263 DOI: 10.1038/nprot.2006.61  0.32
2006 Aublin A, Ciofani M, Willkomm N, Hamrouni A, Szymczak-Workman AL, Takahashi T, Sandjeu Y, Guillaume P, Vignali DA, Michielin O, Zúñiga-Pflücker JC, Maryanski JL. A natural structural variant of the mouse TCR beta-chain displays intrinsic receptor function and antigen specificity. Journal of Immunology (Baltimore, Md. : 1950). 177: 8587-94. PMID 17142757 DOI: 10.4049/Jimmunol.177.12.8587  0.323
2006 Holst J, Vignali KM, Burton AR, Vignali DA. Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nature Methods. 3: 191-7. PMID 16489336 DOI: 10.1038/nmeth858  0.371
2005 Szymczak AL, Workman CJ, Gil D, Dilioglou S, Vignali KM, Palmer E, Vignali DA. The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 175: 270-5. PMID 15972658  0.366
2005 Workman CJ, Vignali DA. Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). Journal of Immunology (Baltimore, Md. : 1950). 174: 688-95. PMID 15634887  0.439
2004 Li N, Workman CJ, Martin SM, Vignali DA. Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223). Journal of Immunology (Baltimore, Md. : 1950). 173: 6806-12. PMID 15557174  0.349
2004 Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, Hipkiss EL, Ravi S, Kowalski J, Levitsky HI, Powell JD, Pardoll DM, Drake CG, Vignali DA. Role of LAG-3 in regulatory T cells. Immunity. 21: 503-13. PMID 15485628 DOI: 10.1016/J.Immuni.2004.08.010  0.407
2004 Leen AM, Sili U, Vanin EF, Jewell AM, Xie W, Vignali D, Piedra PA, Brenner MK, Rooney CM. Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells. Blood. 104: 2432-40. PMID 15265797 DOI: 10.1182/Blood-2004-02-0646  0.472
2004 Workman CJ, Cauley LS, Kim IJ, Blackman MA, Woodland DL, Vignali DA. Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 172: 5450-5. PMID 15100286 DOI: 10.4049/Jimmunol.172.9.5450  0.427
2003 Wagner HJ, Sili U, Gahn B, Vigouroux S, Huls MH, Xie W, Vignali D, Brenner MK, Heslop HE, Rooney CM. Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: influence of recombinant IL12 and IL15. Cytotherapy. 5: 231-40. PMID 12850791 DOI: 10.1080/14653240310001262  0.395
2002 Arnold PY, Vignali KM, Miller TB, La Gruta NL, Cauley LS, Haynes L, Scott Adams P, Swain SL, Woodland DL, Vignali DA. Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells. Journal of Immunological Methods. 271: 137-51. PMID 12445737 DOI: 10.1016/S0022-1759(02)00343-5  0.329
2002 Workman CJ, Rice DS, Dugger KJ, Kurschner C, Vignali DA. Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). European Journal of Immunology. 32: 2255-63. PMID 12209638 DOI: 10.1002/1521-4141(200208)32:8<2255::Aid-Immu2255>3.0.Co;2-A  0.349
Low-probability matches (unlikely to be authored by this person)
2008 Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H. Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity. Journal of Virology. 82: 3078-89. PMID 18184707 DOI: 10.1128/Jvi.01812-07  0.299
2015 He Y, Rangarajan S, Kerzic M, Luo M, Chen Y, Wang Q, Yin Y, Workman CJ, Vignali KM, Vignali DA, Mariuzza RA, Orban J. Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR. The Journal of Biological Chemistry. PMID 26109064 DOI: 10.1074/Jbc.M115.663799  0.298
2004 La Gruta NL, Liu H, Dilioglou S, Rhodes M, Wiest DL, Vignali DA. Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation. Journal of Immunology (Baltimore, Md. : 1950). 172: 3662-9. PMID 15004169  0.296
2016 Visperas A, Vignali DA. Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them? Journal of Immunology (Baltimore, Md. : 1950). 197: 3762-3770. PMID 27815439 DOI: 10.4049/jimmunol.1601118  0.294
2016 Tomita Y, Satomi M, Baran WB, Gan EJ, Workman AS, Workman CJ, Vignali DA, Burlingham WJ. Kinetics of Alloantigen-Specific Regulatory CD4 T Cell Development and Tissue Distribution After Donor-Specific Transfusion and Costimulatory Blockade. Transplantation Direct. 2: e73. PMID 27500263 DOI: 10.1097/TXD.0000000000000580  0.292
2003 Clatza A, Bonifaz LC, Vignali DA, Moreno J. CD40-induced aggregation of MHC class II and CD80 on the cell surface leads to an early enhancement in antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 171: 6478-87. PMID 14662847  0.29
2011 Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA. Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. Journal of Immunology (Baltimore, Md. : 1950). 186: 6661-6. PMID 21576509 DOI: 10.4049/Jimmunol.1100315  0.288
2014 Delgoffe GM, Vignali DA. A Fox of a different color: FoxA1 programs a new regulatory T cell subset. Nature Medicine. 20: 236-7. PMID 24603791 DOI: 10.1038/Nm.3493  0.287
2007 Li N, Boyd K, Dempsey PJ, Vignali DA. Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development. Journal of Immunology (Baltimore, Md. : 1950). 178: 4214-21. PMID 17371977  0.287
2002 Cauley LS, Cookenham T, Miller TB, Adams PS, Vignali KM, Vignali DA, Woodland DL. Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype. Journal of Immunology (Baltimore, Md. : 1950). 169: 6655-8. PMID 12471092 DOI: 10.4049/Jimmunol.169.12.6655  0.286
2012 Vignali DA. Mechanisms of T(reg) Suppression: Still a Long Way to Go. Frontiers in Immunology. 3: 191. PMID 22783262 DOI: 10.3389/fimmu.2012.00191  0.283
2015 Park AC, Huang G, Jankowska-Gan E, Massoudi D, Kernien JF, Vignali DA, Sullivan JA, Wilkes DS, Burlingham WJ, Greenspan DS. Mucosal administration of collagen V ameliorates atherosclerotic plaque burden by inducing IL-35-dependent tolerance. The Journal of Biological Chemistry. PMID 26721885 DOI: 10.1074/Jbc.M115.681882  0.277
2012 Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S, Grosso JF, Netto G, Smeltzer MP, Chaux A, ... ... Vignali DA, et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Research. 72: 917-27. PMID 22186141 DOI: 10.1158/0008-5472.Can-11-1620  0.277
2015 Sawant DV, Hamilton K, Vignali DA. Interleukin-35: Expanding Its Job Profile. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 35: 499-512. PMID 25919641 DOI: 10.1089/Jir.2015.0015  0.27
2011 Collison LW, Vignali DA. In vitro Treg suppression assays. Methods in Molecular Biology (Clifton, N.J.). 707: 21-37. PMID 21287326 DOI: 10.1007/978-1-61737-979-6_2  0.263
2021 Hensley MK, Bain WG, Jacobs J, Nambulli S, Parikh U, Cillo A, Staines B, Heaps A, Sobolewski MD, Rennick LJ, Macatangay BJC, Klamar-Blain C, Kitsios GD, Methé B, Somasundaram A, ... ... Vignali DA, et al. Intractable COVID-19 and Prolonged SARS-CoV-2 Replication in a CAR-T-cell Therapy Recipient: A Case Study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 33507235 DOI: 10.1093/cid/ciab072  0.259
2011 Bettini M, Vignali DA. T cell-driven initiation and propagation of autoimmune diabetes. Current Opinion in Immunology. 23: 754-60. PMID 22056379 DOI: 10.1016/j.coi.2011.10.002  0.257
2012 Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, Fairweather D, Satoskar AR, Garcia KC, Hunter CA, Drake CG, Murray PJ, Vignali DA. The composition and signaling of the IL-35 receptor are unconventional. Nature Immunology. 13: 290-9. PMID 22306691 DOI: 10.1038/Ni.2227  0.252
2005 Church LD, Hessler G, Goodall JE, Rider DA, Workman CJ, Vignali DA, Bacon PA, Gulbins E, Young SP. TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx. Journal of Leukocyte Biology. 78: 266-78. PMID 15817701 DOI: 10.1189/Jlb.1003456  0.245
2014 Sawant DV, Gravano DM, Vogel P, Giacomin P, Artis D, Vignali DA. Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 2904-12. PMID 24532574 DOI: 10.4049/Jimmunol.1202502  0.244
2002 Arnold PY, La Gruta NL, Miller T, Vignali KM, Adams PS, Woodland DL, Vignali DA. The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues. Journal of Immunology (Baltimore, Md. : 1950). 169: 739-49. PMID 12097376  0.24
2016 Dobbins J, Gagnon E, Godec J, Pyrdol J, Vignali DA, Sharpe AH, Wucherpfennig KW. Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling. Science Signaling. 9: ra75. PMID 27460989 DOI: 10.1126/Scisignal.Aaf0626  0.223
2015 Dixon KO, van der Kooij SW, Vignali DA, van Kooten C. Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members. European Journal of Immunology. 45: 1736-47. PMID 25820702 DOI: 10.1002/eji.201445217  0.222
2011 Delgoffe GM, Murray PJ, Vignali DA. Interpreting mixed signals: the cell's cytokine conundrum. Current Opinion in Immunology. 23: 632-8. PMID 21852079 DOI: 10.1016/J.Coi.2011.07.013  0.213
2017 Andrews LP, Marciscano AE, Drake CG, Vignali DA. LAG3 (CD223) as a cancer immunotherapy target. Immunological Reviews. 276: 80-96. PMID 28258692 DOI: 10.1111/imr.12519  0.212
2008 Collison LW, Vignali DA. Interleukin-35: odd one out or part of the family? Immunological Reviews. 226: 248-62. PMID 19161429 DOI: 10.1111/J.1600-065X.2008.00704.X  0.209
2005 Szymczak AL, Vignali DA. Plasticity and rigidity in adaptor protein-2-mediated internalization of the TCR:CD3 complex. Journal of Immunology (Baltimore, Md. : 1950). 174: 4153-60. PMID 15778375  0.208
2012 Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS. Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes. 61: 857-65. PMID 22315318 DOI: 10.2337/Db11-1113  0.207
2011 Jones LL, Vignali DA. Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily. Immunologic Research. 51: 5-14. PMID 21553332 DOI: 10.1007/S12026-011-8209-Y  0.194
2018 Burlingham W, Sullivan JA, Lema DA, Tomita Y, Zhou Y, Vignali D. The Mark of Zorro Transplantation. 102: S328-S329. DOI: 10.1097/01.Tp.0000543057.28120.C8  0.183
2020 Grebinoski S, Vignali DA. Inhibitory receptor agonists: the future of autoimmune disease therapeutics? Current Opinion in Immunology. 67: 1-9. PMID 32619929 DOI: 10.1016/j.coi.2020.06.001  0.182
2016 Zhang Q, Vignali DA. Co-stimulatory and Co-inhibitory Pathways in Autoimmunity. Immunity. 44: 1034-1051. PMID 27192568 DOI: 10.1016/j.immuni.2016.04.017  0.169
2013 Delgoffe GM, Vignali DA. STAT heterodimers in immunity: A mixed message or a unique signal? Jak-Stat. 2: e23060. PMID 24058793 DOI: 10.4161/jkst.23060  0.169
2006 El Kasmi KC, Holst J, Coffre M, Mielke L, de Pauw A, Lhocine N, Smith AM, Rutschman R, Kaushal D, Shen Y, Suda T, Donnelly RP, Myers MG, Alexander W, Vignali DA, et al. General nature of the STAT3-activated anti-inflammatory response. Journal of Immunology (Baltimore, Md. : 1950). 177: 7880-8. PMID 17114459 DOI: 10.4049/Jimmunol.177.11.7880  0.167
2013 Bettini ML, Bettini M, Nakayama M, Guy CS, Vignali DA. Generation of T cell receptor-retrogenic mice: improved retroviral-mediated stem cell gene transfer. Nature Protocols. 8: 1837-40. PMID 24008379 DOI: 10.1038/Nprot.2013.111  0.165
2023 Cruz T, Agudelo Garcia PA, Chamucero-Millares JA, Bondonese A, Mitash N, Sembrat J, Tabib T, Zhang W, Seyed N, Peters V, Stacey S, Vignali D, Mora AL, Lafyatis R, Rojas M. End-Stage Idiopathic Pulmonary Fibrosis Lung Microenvironment Promotes Impaired NK Activity. Journal of Immunology (Baltimore, Md. : 1950). PMID 37566492 DOI: 10.4049/jimmunol.2300182  0.162
2024 Chen F, Onkar S, Zou J, Li Y, Arbore H, Maley S, Tseng G, Lucas P, Bruno T, Vignali D, Foldi J, Balic M, Lee AV, Oesterreich S. Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast Cancer. Research Square. PMID 39184073 DOI: 10.21203/rs.3.rs-4579052/v1  0.158
2012 Vignali DA, Kuchroo VK. IL-12 family cytokines: immunological playmakers. Nature Immunology. 13: 722-8. PMID 22814351 DOI: 10.1038/Ni.2366  0.156
2010 Tseng PH, Matsuzawa A, Zhang W, Mino T, Vignali DA, Karin M. Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nature Immunology. 11: 70-5. PMID 19898473 DOI: 10.1038/Ni.1819  0.155
2012 Bettini M, Castellaw AH, Lennon GP, Burton AR, Vignali DA. Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35. Diabetes. 61: 1519-26. PMID 22427377 DOI: 10.2337/db11-0784  0.146
2012 Jones LL, Chaturvedi V, Uyttenhove C, Van Snick J, Vignali DA. Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family. Molecular Immunology. 51: 234-44. PMID 22487722 DOI: 10.1016/J.Molimm.2012.03.025  0.141
2004 Arnold PY, Burton AR, Vignali DA. Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer. Journal of Immunology (Baltimore, Md. : 1950). 173: 3103-11. PMID 15322170  0.14
2005 Szymczak AL, Vignali DA. Development of 2A peptide-based strategies in the design of multicistronic vectors. Expert Opinion On Biological Therapy. 5: 627-38. PMID 15934839 DOI: 10.1517/14712598.5.5.627  0.136
2008 Matsuzawa A, Tseng PH, Vallabhapurapu S, Luo JL, Zhang W, Wang H, Vignali DA, Gallagher E, Karin M. Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex. Science (New York, N.Y.). 321: 663-8. PMID 18635759 DOI: 10.1126/Science.1157340  0.131
2010 Vignali DA. CD4 on the road to coreceptor status. Journal of Immunology (Baltimore, Md. : 1950). 184: 5933-4. PMID 20483776 DOI: 10.4049/jimmunol.1090037  0.131
2008 Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, Vignali DA, Bergsagel PL, Karin M. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nature Immunology. 9: 1364-70. PMID 18997792 DOI: 10.1038/ni.1678  0.109
2008 Wang H, Matsuzawa A, Brown SA, Zhou J, Guy CS, Tseng PH, Forbes K, Nicholson TP, Sheppard PW, Häcker H, Karin M, Vignali DA. Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 105: 20197-202. PMID 19091944 DOI: 10.1073/pnas.0810461105  0.109
2005 Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell SK, Vignali DA, Ryan MD, Wilber AC, McIvor RS, Tolar J, Blazar BR. A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 569-74. PMID 15964244 DOI: 10.1016/J.Ymthe.2005.04.013  0.106
2013 Herold KC, Vignali DA, Cooke A, Bluestone JA. Type 1 diabetes: translating mechanistic observations into effective clinical outcomes. Nature Reviews. Immunology. 13: 243-56. PMID 23524461 DOI: 10.1038/Nri3422  0.099
2021 Cruz T, Jia M, Sembrat J, Tabib T, Agostino N, Bruno TC, Vignali D, Sanchez P, Lafyatis R, Mora AL, Benos P, Rojas M. Reduce Proportion and Activity of NK Cells in the Lung of Idiopathic Pulmonary Fibrosis Patients. American Journal of Respiratory and Critical Care Medicine. PMID 34077698 DOI: 10.1164/rccm.202012-4418LE  0.096
2016 Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, ... ... Vignali DA, et al. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science (New York, N.Y.). 353. PMID 27708076 DOI: 10.1126/Science.Aah3374  0.087
2013 Vignali DA. Interview: immunotherapeutic manipulation of the tumor microenvironment. Immunotherapy. 5: 1279-81. PMID 24283836 DOI: 10.2217/imt.13.135  0.076
2012 Turnis ME, Korman AJ, Drake CG, Vignali DA. Combinatorial Immunotherapy: PD-1 may not be LAG-ing behind any more. Oncoimmunology. 1: 1172-1174. PMID 23170269 DOI: 10.4161/onci.20593  0.075
2012 Szymczak-Workman AL, Vignali KM, Vignali DA. Design and construction of 2A peptide-linked multicistronic vectors. Cold Spring Harbor Protocols. 2012: 199-204. PMID 22301656 DOI: 10.1101/pdb.ip067876  0.07
2012 Szymczak-Workman AL, Vignali KM, Vignali DA. Verification of 2A peptide cleavage. Cold Spring Harbor Protocols. 2012: 255-7. PMID 22301658 DOI: 10.1101/pdb.prot067892  0.059
2011 Megas C, Hatzivassiliou EG, Yin Q, Marinopoulou E, Hadweh P, Vignali DA, Mosialos G. Mutational analysis of TRAF6 reveals a conserved functional role of the RING dimerization interface and a potentially necessary but insufficient role of RING-dependent TRAF6 polyubiquitination towards NF-κB activation. Cellular Signalling. 23: 772-7. PMID 21185369 DOI: 10.1016/j.cellsig.2010.12.004  0.055
2018 El-Bouri WK, Vignali D, Iliadi K, Bulters DO, Marchbanks RJ, Birch AA, Simpson DM. Quantifying the contribution of intracranial pressure and arterial blood pressure to spontaneous tympanic membrane displacement. Physiological Measurement. PMID 29999499 DOI: 10.1088/1361-6579/aad308  0.048
2012 Szymczak-Workman AL, Vignali KM, Vignali DA. Generation of 2A-linked multicistronic cassettes by recombinant PCR. Cold Spring Harbor Protocols. 2012: 251-4. PMID 22301657 DOI: 10.1101/pdb.prot067884  0.046
2021 Bain W, Yang H, Shah FA, Suber T, Drohan C, Al-Yousif N, DeSensi RS, Bensen N, Schaefer C, Rosborough BR, Somasundaram A, Workman CJ, Lampenfeld C, Cillo AR, Cardello C, ... ... Vignali DA, et al. COVID-19 versus Non-COVID ARDS: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers and Clinical Outcomes. Annals of the American Thoracic Society. PMID 33544045 DOI: 10.1513/AnnalsATS.202008-1026OC  0.033
2018 Campbell-Bell CM, Birch AA, Vignali D, Bulters D, Marchbanks RJ. Reference intervals for the evoked tympanic membrane displacement measurement: a non-invasive measure of intracranial pressure. Physiological Measurement. 39: 015008. PMID 29239860 DOI: 10.1088/1361-6579/aaa1d3  0.018
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