Brian O. Bachmann, Ph.D. - Publications

Affiliations: 
2003- Chemistry Vanderbilt University, Nashville, TN 
Area:
Chemistry, Biosynthesis, Synthetic Biology
Website:
http://biosyntheticstudies.com/

52/113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dulin CC, Sharma P, Frigo L, Voehler MW, Iverson TM, Bachmann BO. EvdS6 is a bifunctional decarboxylase from the everninomicin gene cluster. The Journal of Biological Chemistry. 104893. PMID 37286037 DOI: 10.1016/j.jbc.2023.104893  0.335
2020 Limbrick EM, Ynigez-Gutierrez AE, Dulin CC, Derewacz DK, Spraggins JM, McCulloch KM, Iverson TM, Bachmann BO. Methyltransferase contingencies in the pathway of everninomicin D antibiotics and analogs. Chembiochem : a European Journal of Chemical Biology. PMID 32686210 DOI: 10.1002/Cbic.202000305  0.317
2019 Yñigez-Gutierrez AE, Bachmann BO. Fixing the Unfixable: The Art of Optimizing Natural Products for Human Medicine. Journal of Medicinal Chemistry. PMID 31026161 DOI: 10.1021/Acs.Jmedchem.9B00246  0.321
2018 Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM. The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains. Biochemistry. PMID 30525509 DOI: 10.1021/acs.biochem.8b00836  0.364
2018 Covington BC, Spraggins JM, Ynigez-Gutierrez AE, Hylton ZB, Bachmann BO. Response of Hypogean Actinobacterial Genera Secondary Metabolism to Chemical and Biological Stimuli. Applied and Environmental Microbiology. PMID 30030223 DOI: 10.1128/Aem.01125-18  0.319
2016 Masuyer G, Cozier GE, Kramer GJ, Bachmann BO, Acharya KR. Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor. The Febs Journal. PMID 27754586 DOI: 10.1111/Febs.13928  0.588
2016 Bachmann BO. Applied evolutionary theories for engineering of secondary metabolic pathways. Current Opinion in Chemical Biology. 35: 133-141. PMID 27736648 DOI: 10.1016/J.Cbpa.2016.09.021  0.331
2016 Covington BC, McLean JA, Bachmann BO. Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites. Natural Product Reports. PMID 27604382 DOI: 10.1039/C6Np00048G  0.31
2016 Tianero MD, Pierce E, Raghuraman S, Sardar D, McIntosh JA, Heemstra JR, Schonrock Z, Covington BC, Maschek JA, Cox JE, Bachmann BO, Olivera BM, Ruffner DE, Schmidt EW. Metabolic model for diversity-generating biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831074 DOI: 10.1073/Pnas.1525438113  0.556
2015 Sartor L, Ibarra C, Al-Mestarihi A, Bachmann BO, Vey JL. Structure of DnmZ, a nitrososynthase in the Streptomyces peucetius anthracycline biosynthetic pathway. Acta Crystallographica. Section F, Structural Biology Communications. 71: 1205-14. PMID 26457508 DOI: 10.1107/S2053230X15014272  0.796
2015 McCulloch KM, McCranie EK, Smith JA, Sarwar M, Mathieu JL, Gitschlag BL, Du Y, Bachmann BO, Iverson TM. Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily. Proceedings of the National Academy of Sciences of the United States of America. 112: 11547-52. PMID 26240321 DOI: 10.1073/Pnas.1500964112  0.419
2015 Derewacz DK, Covington BC, McLean JA, Bachmann BO. Mapping Microbial Response Metabolomes for Induced Natural Product Discovery. Acs Chemical Biology. PMID 26039241 DOI: 10.1021/Acschembio.5B00001  0.306
2014 Kramer GJ, Mohd A, Schwager SL, Masuyer G, Acharya KR, Sturrock ED, Bachmann BO. Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes. Acs Medicinal Chemistry Letters. 5: 346-51. PMID 24900839 DOI: 10.1021/Ml4004588  0.599
2014 McCranie EK, Bachmann BO. Bioactive oligosaccharide natural products. Natural Product Reports. 31: 1026-42. PMID 24883430 DOI: 10.1039/C3Np70128J  0.312
2014 Birmingham WR, Starbird CA, Panosian TD, Nannemann DP, Iverson TM, Bachmann BO. Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nature Chemical Biology. 10: 392-9. PMID 24657930 DOI: 10.1038/Nchembio.1494  0.772
2013 Al-Mestarihi A, Romo A, Liu HW, Bachmann BO. Nitrososynthase-triggered oxidative carbon-carbon bond cleavage in baumycin biosynthesis. Journal of the American Chemical Society. 135: 11457-60. PMID 23885759 DOI: 10.1021/Ja404987R  0.781
2013 Derewacz DK, Goodwin CR, McNees CR, McLean JA, Bachmann BO. Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proceedings of the National Academy of Sciences of the United States of America. 110: 2336-41. PMID 23341601 DOI: 10.1073/Pnas.1218524110  0.311
2012 Iverson TM, Panosian TD, Birmingham WR, Nannemann DP, Bachmann BO. Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. Biochemistry. 51: 1964-75. PMID 22329805 DOI: 10.1021/Bi201761H  0.779
2011 Du Y, Derewacz DK, Deguire SM, Teske J, Ravel J, Sulikowski GA, Bachmann BO. Biosynthesis of the Apoptolidins in Nocardiopsis sp. FU 40. Tetrahedron. 67: 6568-6575. PMID 21869849 DOI: 10.1016/J.Tet.2011.05.106  0.331
2011 Nannemann DP, Birmingham WR, Scism RA, Bachmann BO. Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis. Future Medicinal Chemistry. 3: 809-19. PMID 21644826 DOI: 10.4155/Fmc.11.48  0.75
2011 Panosian TD, Nannemann DP, Watkins GR, Phelan VV, McDonald WH, Wadzinski BE, Bachmann BO, Iverson TM. Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle. The Journal of Biological Chemistry. 286: 8043-54. PMID 21193409 DOI: 10.1074/Jbc.M110.201350  0.775
2010 Vey JL, Al-Mestarihi A, Hu Y, Funk MA, Bachmann BO, Iverson TM. Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis . Biochemistry. 49: 9306-17. PMID 20866105 DOI: 10.1021/Bi101336U  0.792
2010 Panosian TD, Nannemann DP, Bachmann BO, Iverson TM. Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 811-4. PMID 20606280 DOI: 10.1107/S1744309110017549  0.745
2010 Akif M, Ntai I, Sturrock ED, Isaac RE, Bachmann BO, Acharya KR. Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochemical and Biophysical Research Communications. 398: 532-6. PMID 20599761 DOI: 10.1016/J.Bbrc.2010.06.113  0.698
2010 Nannemann DP, Kaufmann KW, Meiler J, Bachmann BO. Design and directed evolution of a dideoxy purine nucleoside phosphorylase. Protein Engineering, Design & Selection : Peds. 23: 607-16. PMID 20525731 DOI: 10.1093/Protein/Gzq033  0.798
2010 Bachmann BO, McNees R, Melancon BJ, Ghidu VP, Clark R, Crews BC, Deguire SM, Marnett LJ, Sulikowski GA. Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry. Organic Letters. 12: 2944-7. PMID 20515014 DOI: 10.1021/Ol1009398  0.672
2010 Du Y, Gisselberg JE, Johnson JD, Lee PJ, Prigge ST, Bachmann BO. Lactococcus lactis fabH, encoding beta-ketoacyl-acyl carrier protein synthase, can be functionally replaced by the Plasmodium falciparum congener. Applied and Environmental Microbiology. 76: 3959-66. PMID 20418430 DOI: 10.1128/Aem.00170-10  0.352
2010 Carter MD, Phelan VV, Sandlin RD, Bachmann BO, Wright DW. Lipophilic mediated assays for beta-hematin inhibitors. Combinatorial Chemistry & High Throughput Screening. 13: 285-92. PMID 20230372 DOI: 10.2174/138620710790980496  0.672
2010 Reniere ML, Ukpabi GN, Harry SR, Stec DF, Krull R, Wright DW, Bachmann BO, Murphy ME, Skaar EP. The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Molecular Microbiology. 75: 1529-38. PMID 20180905 DOI: 10.1111/J.1365-2958.2010.07076.X  0.303
2010 Scism RA, Bachmann BO. Five-component cascade synthesis of nucleotide analogues in an engineered self-immobilized enzyme aggregate. Chembiochem : a European Journal of Chemical Biology. 11: 67-70. PMID 19918830 DOI: 10.1002/Cbic.200900620  0.763
2009 Ghidu VP, Ntai I, Wang J, Jacobs AT, Marnett LJ, Bachmann BO, Sulikowski GA. Combined chemical and biosynthetic route to access a new apoptolidin congener. Organic Letters. 11: 3032-4. PMID 19552384 DOI: 10.1021/Ol901045V  0.673
2009 Phelan VV, Du Y, McLean JA, Bachmann BO. Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange. Chemistry & Biology. 16: 473-8. PMID 19477411 DOI: 10.1016/J.Chembiol.2009.04.007  0.7
2009 Bachmann BO, Ravel J. Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data. Methods in Enzymology. 458: 181-217. PMID 19374984 DOI: 10.1016/S0076-6879(09)04808-3  0.315
2008 Hu Y, Al-Mestarihi A, Grimes CL, Kahne D, Bachmann BO. A unifying nitrososynthase involved in nitrosugar biosynthesis. Journal of the American Chemical Society. 130: 15756-7. PMID 18983146 DOI: 10.1021/Ja8051415  0.772
2008 Hu Y, Phelan VV, Farnet CM, Zazopoulos E, Bachmann BO. Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes. Chembiochem : a European Journal of Chemical Biology. 9: 1603-8. PMID 18512205 DOI: 10.1002/Cbic.200800029  0.753
2008 Ntai I, Bachmann BO. Identification of ACE pharmacophore in the phosphonopeptide metabolite K-26. Bioorganic & Medicinal Chemistry Letters. 18: 3068-71. PMID 18096385 DOI: 10.1016/J.Bmcl.2007.11.130  0.701
2007 Scism RA, Stec DF, Bachmann BO. Synthesis of nucleotide analogues by a promiscuous phosphoribosyltransferase. Organic Letters. 9: 4179-82. PMID 17854193 DOI: 10.1021/Ol7016802  0.761
2007 Bachmann BO. Foundations for directed alkaloid biosynthesis. Chemistry & Biology. 14: 875-6. PMID 17719485 DOI: 10.1016/J.Chembiol.2007.08.001  0.371
2007 Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO. Benzodiazepine biosynthesis in Streptomyces refuineus. Chemistry & Biology. 14: 691-701. PMID 17584616 DOI: 10.1016/J.Chembiol.2007.05.009  0.757
2007 Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO. Benzodiazepine Biosynthesis in Streptomyces refuineus (DOI:10.1016/j.chembiol.2007.05.009) Chemistry and Biology. 14: 870. DOI: 10.1016/J.Chembiol.2007.07.006  0.746
2006 Ntai I, Phelan VV, Bachmann BO. Phosphonopeptide K-26 biosynthetic intermediates in Astrosporangium hypotensionis. Chemical Communications (Cambridge, England). 4518-20. PMID 17283804 DOI: 10.1039/B611768F  0.767
2006 Wilkinson B, Bachmann BO. Biocatalysis in pharmaceutical preparation and alteration. Current Opinion in Chemical Biology. 10: 169-76. PMID 16500136 DOI: 10.1016/J.Cbpa.2006.02.006  0.313
2005 Ntai I, Manier ML, Hachey DL, Bachmann BO. Biosynthetic origins of C-P bond containing tripeptide K-26. Organic Letters. 7: 2763-5. PMID 15957941 DOI: 10.1021/Ol051091D  0.691
2003 Zazopoulos E, Huang K, Staffa A, Liu W, Bachmann BO, Nonaka K, Ahlert J, Thorson JS, Shen B, Farnet CM. A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nature Biotechnology. 21: 187-90. PMID 12536216 DOI: 10.1038/Nbt784  0.358
2002 Miller MT, Bachmann BO, Townsend CA, Rosenzweig AC. The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots. Proceedings of the National Academy of Sciences of the United States of America. 99: 14752-7. PMID 12409610 DOI: 10.1073/Pnas.232361199  0.539
2002 Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS. The calicheamicin gene cluster and its iterative type I enediyne PKS. Science (New York, N.Y.). 297: 1173-6. PMID 12183629 DOI: 10.1126/Science.1072105  0.316
2001 Miller MT, Bachmann BO, Townsend CA, Rosenzweig AC. Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine. Nature Structural Biology. 8: 684-9. PMID 11473258 DOI: 10.1038/90394  0.514
2001 Zhou J, Kelly WL, Bachmann BO, Gunsior M, Townsend CA, Solomon EI. Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities. Journal of the American Chemical Society. 123: 7388-98. PMID 11472170 DOI: 10.1021/Ja004025+  0.77
2000 Bachmann BO, Townsend CA. Kinetic mechanism of the beta-lactam synthetase of Streptomyces clavuligerus. Biochemistry. 39: 11187-93. PMID 10985764 DOI: 10.1021/Bi000709I  0.585
1998 Bachmann BO, Li R, Townsend CA. beta-Lactam synthetase: a new biosynthetic enzyme. Proceedings of the National Academy of Sciences of the United States of America. 95: 9082-6. PMID 9689037 DOI: 10.1073/Pnas.95.16.9082  0.542
1998 Zhou J, Gunsior M, Bachmann BO, Townsend CA, Solomon EI. Substrate binding to the α-ketoglutarate-dependent non-heme iron enzyme clavaminate synthase 2: Coupling mechanism of oxidative decarboxylation and hydroxylation [14] Journal of the American Chemical Society. 120: 13539-13540. DOI: 10.1021/Ja983534X  0.771
1995 Buynak JD, Wu K, Bachmann B, Khasnis D, Hua L, Nguyen HK, Carver CL. Synthesis and biological activity of 7-alkylidenecephems Journal of Medicinal Chemistry. 38: 1022-1034. PMID 7699694 DOI: 10.1021/Jm00006A022  0.39
Low-probability matches (unlikely to be authored by this person)
1997 Buynak JD, Srinivasa Rao A, Ford GP, Carver C, Adam G, Geng B, Bachmann B, Shobassy S, Lackey S. 7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase Journal of Medicinal Chemistry. 40: 3423-3433. PMID 9341917 DOI: 10.1021/Jm970351X  0.297
2020 Limbrick E, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez A, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO. A bifunctional nitrone conjugated secondary metabolite targeting the ribosome. Journal of the American Chemical Society. PMID 32709196 DOI: 10.1021/Jacs.0C04675  0.295
2005 McAlpine JB, Bachmann BO, Piraee M, Tremblay S, Alarco AM, Zazopoulos E, Farnet CM. Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example. Journal of Natural Products. 68: 493-6. PMID 15844935 DOI: 10.1021/Np0401664  0.287
2020 Algoo JD, Penton K, Bachmann B. Isolation and Single Cell Chemical Biological Analysis of Natural Product Producing Cave Microorganisms The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05620  0.287
2012 Goodwin CR, Fenn LS, Derewacz DK, Bachmann BO, McLean JA. Structural mass spectrometry: rapid methods for separation and analysis of peptide natural products. Journal of Natural Products. 75: 48-53. PMID 22216918 DOI: 10.1021/Np200457R  0.28
2005 Bachmann BO. Decoding chemical structures from genomes. Nature Chemical Biology. 1: 244-5. PMID 16408048 DOI: 10.1038/Nchembio1005-244  0.273
2010 Bachmann BO. Biosynthesis: is it time to go retro? Nature Chemical Biology. 6: 390-3. PMID 20479744 DOI: 10.1038/Nchembio.377  0.272
2024 Yñigez-Gutierrez AE, Wurm JE, Froese JT, Rosenthal NE, Bachmann BO. Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins. Acs Chemical Biology. PMID 38289021 DOI: 10.1021/acschembio.3c00693  0.269
2014 Goodwin CR, Sherrod SD, Marasco CC, Bachmann BO, Schramm-Sapyta N, Wikswo JP, McLean JA. Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. Analytical Chemistry. 86: 6563-71. PMID 24856386 DOI: 10.1021/Ac5010794  0.268
2019 Steinberger J, Robert F, Hallé M, Williams DE, Cencic R, Sawhney N, Pelletier D, Williams P, Igarashi Y, Porco JA, Rodriguez AD, Kopp B, Bachmann B, Andersen RJ, Pelletier J. Tracing MYC Expression for Small Molecule Discovery. Cell Chemical Biology. PMID 30880156 DOI: 10.1016/J.Chembiol.2019.02.007  0.265
2014 Stow SM, Goodwin CR, Kliman M, Bachmann BO, McLean JA, Lybrand TP. Distance geometry protocol to generate conformations of natural products to structurally interpret ion mobility-mass spectrometry collision cross sections. The Journal of Physical Chemistry. B. 118: 13812-20. PMID 25360896 DOI: 10.1021/Jp509398E  0.263
2018 Earl DC, Ferrell PB, Leelatian N, Froese JT, Reisman BJ, Irish JM, Bachmann BO. Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics. Nature Communications. 9: 39. PMID 29295987 DOI: 10.1038/S41467-017-02470-8  0.26
2014 Derewacz DK, McNees CR, Scalmani G, Covington CL, Shanmugam G, Marnett LJ, Polavarapu PL, Bachmann BO. Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete. Journal of Natural Products. PMID 25046128 DOI: 10.1021/Np400742P  0.253
2015 Goodwin CR, Covington BC, Derewacz DK, McNees CR, Wikswo JP, McLean JA, Bachmann BO. Structuring Microbial Metabolic Responses to Multiplexed Stimuli via Self-Organizing Metabolomics Maps. Chemistry & Biology. 22: 661-70. PMID 25937311 DOI: 10.1016/J.Chembiol.2015.03.020  0.252
2019 Ellis BM, Fischer CN, Martin LB, Bachmann BO, McLean JA. Spatiochemically Profiling Microbial Interactions with Membrane Scaffolded Desorption Electrospray Ionization-Ion Mobility- Imaging Mass Spectrometry and Unsupervised Segmentation. Analytical Chemistry. PMID 31600444 DOI: 10.1021/Acs.Analchem.9B02992  0.252
2016 Challis GL, Bachmann BO. Editorial overview: The mechanistic magic of specialised metabolism Current Opinion in Chemical Biology. 35: A4-A6. DOI: 10.1016/J.Cbpa.2016.12.012  0.249
2015 DeGuire SM, Earl DC, Du Y, Crews BA, Jacobs AT, Ustione A, Daniel C, Chong KM, Marnett LJ, Piston DW, Bachmann BO, Sulikowski GA. Fluorescent probes of the apoptolidins and their utility in cellular localization studies. Angewandte Chemie (International Ed. in English). 54: 961-4. PMID 25430909 DOI: 10.1002/Anie.201408906  0.248
1994 Buynak JD, Khasnis D, Bachmann B, Wu K, Lamb G. Synthesis and mechanistic evaluation of 7-vinylidenecephem sulfones as β-lactamase inhibitors Journal of the American Chemical Society. 116: 10955-10965. DOI: 10.1021/Ja00103A010  0.247
2014 Bachmann BO, Van Lanen SG, Baltz RH. Microbial genome mining for accelerated natural products discovery: is a renaissance in the making? Journal of Industrial Microbiology & Biotechnology. 41: 175-84. PMID 24342967 DOI: 10.1007/S10295-013-1389-9  0.239
2016 Chong KM, Leelatian N, Deguire SM, Brockman AA, Earl D, Ihrie RA, Irish JM, Bachmann BO, Sulikowski GA. The use of fluorescently-tagged apoptolidins in cellular uptake and response studies. The Journal of Antibiotics. PMID 26956792 DOI: 10.1038/Ja.2016.22  0.224
2020 Boyce JH, Reisman BJ, Bachmann BO, Porco JA. Synthesis and Multiplexed Activity Profiling of Synthetic Acylphloroglucinol Scaffolds. Angewandte Chemie (International Ed. in English). PMID 32965753 DOI: 10.1002/anie.202010338  0.19
2006 Sulikowski MM, Bachmann BO. Designing a curriculum that goes beyond a list of topics. Acs Chemical Biology. 1: 489-91. PMID 17168533 DOI: 10.1021/Cb6003178  0.175
2021 Preston-Herrera C, Jackson AS, Bachmann BO, Froese JT. Development and application of a high throughput assay system for the detection of Rieske dioxygenase activity. Organic & Biomolecular Chemistry. PMID 33439179 DOI: 10.1039/d0ob02412k  0.158
2021 Reisman BJ, Guo H, Ramsey HE, Wright MT, Reinfeld BI, Ferrell PB, Sulikowski GA, Rathmell WK, Savona MR, Plate L, Rubinstein JL, Bachmann BO. Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase. Nature Chemical Biology. PMID 34857958 DOI: 10.1038/s41589-021-00900-9  0.144
1995 Buynak JD, Geng B, Bachmann B, Ling Hua. The synthesis and lactamase inhibitory activity of 6-(carboxymethylene)penicillins and 7-(carboxymethylene)cephalosporins Bioorganic and Medicinal Chemistry Letters. 5: 1513-1518. DOI: 10.1016/0960-894X(95)00249-S  0.142
2022 Balsamo JA, Penton KE, Zhao Z, Hayes MJ, Lima SM, Irish JM, Bachmann BO. An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products. The Journal of Biological Chemistry. 102300. PMID 35931117 DOI: 10.1016/j.jbc.2022.102300  0.109
2014 Stow SM, Lareau NM, Hines KM, Mcnees CR, Goodwin CR, Bachmann BO, Mclean JA. Structural Separations for Natural Product Characterization by Ion Mobility-Mass Spectrometry: Fundamental Theory to Emerging Applications Natural Products Analysis: Instrumentation, Methods, and Applications. 397-431. DOI: 10.1002/9781118876015.ch11  0.075
2021 Reisman BJ, Barone SM, Bachmann BO, Irish JM. DebarcodeR Increases Fluorescent Cell Barcoding Capacity and Accuracy. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 33960644 DOI: 10.1002/cyto.a.24363  0.069
2011 Kruse FE, Laaser K, Cursiefen C, Heindl LM, Schlötzer-Schrehardt U, Riss S, Bachmann BO. A stepwise approach to donor preparation and insertion increases safety and outcome of Descemet membrane endothelial keratoplasty. Cornea. 30: 580-7. PMID 21598430 DOI: 10.1097/Ico.0B013E3182000E2E  0.068
2011 Schlötzer-Schrehardt U, Bachmann BO, Laaser K, Cursiefen C, Kruse FE. Characterization of the cleavage plane in DESCemet's membrane endothelial keratoplasty. Ophthalmology. 118: 1950-7. PMID 21705086 DOI: 10.1016/J.Ophtha.2011.03.025  0.051
2014 Petsch C, Schlötzer-Schrehardt U, Meyer-Blazejewska E, Frey M, Kruse FE, Bachmann BO. Novel collagen membranes for the reconstruction of the corneal surface. Tissue Engineering. Part A. 20: 2378-89. PMID 24621144 DOI: 10.1089/ten.TEA.2013.0552  0.046
2012 Rudolph M, Laaser K, Bachmann BO, Cursiefen C, Epstein D, Kruse FE. Corneal higher-order aberrations after Descemet's membrane endothelial keratoplasty. Ophthalmology. 119: 528-35. PMID 22197439 DOI: 10.1016/J.Ophtha.2011.08.034  0.043
2012 Laaser K, Bachmann BO, Horn FK, Cursiefen C, Kruse FE. Descemet membrane endothelial keratoplasty combined with phacoemulsification and intraocular lens implantation: advanced triple procedure. American Journal of Ophthalmology. 154: 47-55.e2. PMID 22465365 DOI: 10.1016/J.Ajo.2012.01.020  0.041
2013 Wessel JM, Bachmann BO, Meiller R, Kruse FE. Fungal interface keratitis by Candida orthopsilosis following deep anterior lamellar keratoplasty. Bmj Case Reports. 2013. PMID 23349184 DOI: 10.1136/bcr-2012-008361  0.038
2011 Heindl LM, Riss S, Bachmann BO, Laaser K, Kruse FE, Cursiefen C. Split cornea transplantation for 2 recipients: a new strategy to reduce corneal tissue cost and shortage. Ophthalmology. 118: 294-301. PMID 20723996 DOI: 10.1016/J.Ophtha.2010.05.025  0.036
2011 Laaser K, Bachmann BO, Horn FK, Schlötzer-Schrehardt U, Cursiefen C, Kruse FE. Donor tissue culture conditions and outcome after descemet membrane endothelial keratoplasty. American Journal of Ophthalmology. 151: 1007-1018.e2. PMID 21334592 DOI: 10.1016/J.Ajo.2010.11.027  0.034
2013 Riss S, Heindl LM, Bachmann BO, Kruse FE, Cursiefen C. Microbubble incision as a new rescue technique for big-bubble deep anterior lamellar keratoplasty with failed bubble formation. Cornea. 32: 125-9. PMID 22414925 DOI: 10.1097/ICO.0b013e31824a226f  0.03
2011 Heindl LM, Riss S, Laaser K, Bachmann BO, Kruse FE, Cursiefen C. Split cornea transplantation for 2 recipients - review of the first 100 consecutive patients. American Journal of Ophthalmology. 152: 523-532.e2. PMID 21726851 DOI: 10.1016/J.Ajo.2011.03.021  0.029
2010 Bachmann BO, Laaser K, Cursiefen C, Kruse FE. A method to confirm correct orientation of descemet membrane during descemet membrane endothelial keratoplasty. American Journal of Ophthalmology. 149: 922-925.e2. PMID 20346440 DOI: 10.1016/J.Ajo.2010.01.005  0.028
2010 Dietrich T, Bock F, Yuen D, Hos D, Bachmann BO, Zahn G, Wiegand S, Chen L, Cursiefen C. Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation. Journal of Immunology (Baltimore, Md. : 1950). 184: 535-9. PMID 20018627 DOI: 10.4049/Jimmunol.0903180  0.026
2013 Schlötzer-Schrehardt U, Bachmann BO, Tourtas T, Cursiefen C, Zenkel M, Rössler K, Kruse FE. Reproducibility of graft preparations in Descemet's membrane endothelial keratoplasty. Ophthalmology. 120: 1769-77. PMID 23870299 DOI: 10.1016/j.ophtha.2013.06.038  0.026
2009 Pogorelov P, Cursiefen C, Bachmann BO, Kruse FE. Changes in donor corneal lenticule thickness after Descemet's stripping automated endothelial keratoplasty (DSAEK) with organ-cultured corneas. The British Journal of Ophthalmology. 93: 825-9. PMID 19244269 DOI: 10.1136/Bjo.2008.147389  0.026
2012 Tourtas T, Laaser K, Bachmann BO, Cursiefen C, Kruse FE. Descemet membrane endothelial keratoplasty versus descemet stripping automated endothelial keratoplasty. American Journal of Ophthalmology. 153: 1082-90.e2. PMID 22397955 DOI: 10.1016/J.Ajo.2011.12.012  0.026
2012 Riss S, Heindl LM, Bachmann BO, Kruse FE, Cursiefen C. Pentacam-based big bubble deep anterior lamellar keratoplasty in patients with keratoconus. Cornea. 31: 627-32. PMID 22357390 DOI: 10.1097/ICO.0b013e31823f8c85  0.025
2009 Bachmann BO, Luetjen-Drecoll E, Bock F, Wiegand SJ, Hos D, Dana R, Kruse FE, Cursiefen C. Transient postoperative vascular endothelial growth factor (VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation. The British Journal of Ophthalmology. 93: 1075-80. PMID 19224901 DOI: 10.1136/Bjo.2008.145128  0.024
2014 Price MO, Price FW, Kruse FE, Bachmann BO, Tourtas T. Randomized comparison of topical prednisolone acetate 1% versus fluorometholone 0.1% in the first year after descemet membrane endothelial keratoplasty. Cornea. 33: 880-6. PMID 25062336 DOI: 10.1097/ICO.0000000000000206  0.024
2011 Heindl LM, Schlötzer-Schrehardt U, Cursiefen C, Bachmann BO, Hofmann-Rummelt C, Kruse FE. Myofibroblast metaplasia after descemet membrane endothelial keratoplasty. American Journal of Ophthalmology. 151: 1019-1023.e2. PMID 21457928 DOI: 10.1016/J.Ajo.2010.11.032  0.023
2016 Matthaei M, Gillessen J, Muether PS, Hoerster R, Bachmann BO, Hueber A, Cursiefen C, Heindl LM. Author response: Transforming growth factor beta switch in aqueous humor of patients with fuchs’ endothelial corneal dystrophy Investigative Ophthalmology and Visual Science. 57: 773. DOI: 10.1167/iovs.15-19049  0.022
2016 Schaub F, Hos D, Bucher F, Siebelmann S, Bachmann BO, Cursiefen C. Boston-keratoprosthesis: Preliminary experiences in 13 high-risk eyes from the Department of Ophthalmology of the University of Cologne | Boston-Keratoprothese: Erste Erfahrungen bei 13 Hochrisikoaugen aus der Kölner Universitätsaugenklinik Ophthalmologe. 1-8. DOI: 10.1007/s00347-015-0209-1  0.021
2015 Matthaei M, Gillessen J, Muether PS, Hoerster R, Bachmann BO, Hueber A, Cursiefen C, Heindl LM. Epithelial-Mesenchymal Transition (EMT)-Related Cytokines in the Aqueous Humor of Phakic and Pseudophakic Fuchs' Dystrophy Eyes. Investigative Ophthalmology & Visual Science. 56: 2749-54. PMID 26066605 DOI: 10.1167/iovs.15-16395  0.02
2008 Bachmann BO, Pogorelov P, Kruse FE, Cursiefen C. [Patient satisfaction after posterior lamellar keratoplasty (DSAEK)]. Klinische MonatsbläTter FüR Augenheilkunde. 225: 577-81. PMID 18516779 DOI: 10.1055/s-2008-1027499  0.02
2013 Tourtas T, Heindl LM, Kopsachilis N, Bachmann BO, Kruse FE, Cursiefen C. Use of accidentally torn descemet membrane to successfully complete descemet membrane endothelial keratoplasty. Cornea. 32: 1418-22. PMID 24071808 DOI: 10.1097/Ico.0B013E3182A6Ea4F  0.019
2014 Weller JM, Zenkel M, Schlötzer-Schrehardt U, Bachmann BO, Tourtas T, Kruse FE. Extracellular matrix alterations in late-onset Fuchs' corneal dystrophy. Investigative Ophthalmology & Visual Science. 55: 3700-8. PMID 24833739 DOI: 10.1167/iovs.14-14154  0.018
2014 Tourtas T, Schlomberg J, Wessel JM, Bachmann BO, Schlötzer-Schrehardt U, Kruse FE. Graft adhesion in descemet membrane endothelial keratoplasty dependent on size of removal of host's descemet membrane. Jama Ophthalmology. 132: 155-61. PMID 24336933 DOI: 10.1001/jamaophthalmol.2013.6222  0.016
2016 Hoerster R, Stanzel TP, Bachmann BO, Siebelmann S, Felsch M, Cursiefen C. Intensified Topical Steroids as Prophylaxis for Macular Edema after Posterior Lamellar Keratoplasty Combined with Cataract Surgery American Journal of Ophthalmology. 163: 174-179.e2. DOI: 10.1016/j.ajo.2015.12.008  0.01
2016 Hos D, Dörrie J, Schaft N, Bock F, Notara M, Kruse FE, Krautwald S, Cursiefen C, Bachmann BO. Blockade of CCR7 leads to decreased dendritic cell migration to draining lymph nodes and promotes graft survival in low-risk corneal transplantation Experimental Eye Research. 146: 1-6. DOI: 10.1016/j.exer.2015.12.004  0.01
2015 Tourtas T, Weller JM, Bachmann BO, Kruse FE. Larger Descemetorhexis to Improve Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Does Not Cause Postoperative Peripheral Corneal Edema. Eye & Contact Lens. PMID 26217874 DOI: 10.1097/ICL.0000000000000125  0.01
2015 Schaub F, Simons HG, Roters S, Heindl LM, Kugler W, Bachmann BO, Cursiefen C. [Influence of 20 % sulfur hexafluoride (SF6) on human corneal endothelial cells : An in vitro study]. Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft. PMID 26025298 DOI: 10.1007/S00347-015-0051-5  0.01
2015 Weller JM, Tourtas T, Kruse FE, Schlötzer-Schrehardt U, Fuchsluger T, Bachmann BO. Descemet membrane endothelial keratoplasty as treatment for graft failure after descemet stripping automated endothelial keratoplasty. American Journal of Ophthalmology. 159: 1050-1057.e2. PMID 25790736 DOI: 10.1016/j.ajo.2015.03.010  0.01
2015 Schlötzer-Schrehardt U, Bachmann BO, Tourtas T, Torricelli AA, Singh A, González S, Mei H, Deng SX, Wilson SE, Kruse FE. Ultrastructure of the posterior corneal stroma. Ophthalmology. 122: 693-9. PMID 25458195 DOI: 10.1016/j.ophtha.2014.09.037  0.01
2008 Bachmann BO, Bock F, Wiegand SJ, Maruyama K, Dana MR, Kruse FE, Luetjen-Drecoll E, Cursiefen C. Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation. Archives of Ophthalmology (Chicago, Ill. : 1960). 126: 71-7. PMID 18195221 DOI: 10.1001/Archopht.126.1.71  0.01
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