| Year |
Citation |
Score |
| 2021 |
Sénéchal P, Robert F, Cencic R, Yanagiya A, Chu J, Sonenberg N, Paquet M, Pelletier J. Assessing eukaryotic initiation factor 4F subunit essentiality by CRISPR-induced gene ablation in the mouse. Cellular and Molecular Life Sciences : Cmls. PMID 34559254 DOI: 10.1007/s00018-021-03940-5 |
0.323 |
|
| 2021 |
Lin YH, Wang H, Fiore A, Förster M, Tung LT, Belle JI, Robert F, Pelletier J, Langlais D, Nijnik A. Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma. Journal of Cellular and Molecular Medicine. PMID 34114734 DOI: 10.1111/jcmm.16554 |
0.313 |
|
| 2020 |
Pelletier J, Schmeing TM, Sonenberg N. The multifaceted eukaryotic cap structure. Wiley Interdisciplinary Reviews. Rna. e1636. PMID 33300197 DOI: 10.1002/wrna.1636 |
0.313 |
|
| 2020 |
Steinberger J, Shen L, J Kiniry S, Naineni SK, Cencic R, Amiri M, Aboushawareb SAE, Chu J, Maïga RI, Yachnin BJ, Robert F, Sonenberg N, Baranov PV, Pelletier J. Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions. Nucleic Acids Research. PMID 32766783 DOI: 10.1093/Nar/Gkaa662 |
0.415 |
|
| 2020 |
Robert F, Cencic R, Cai R, Schmeing TM, Pelletier J. RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes. Nucleic Acids Research. PMID 32749456 DOI: 10.1093/Nar/Gkaa646 |
0.382 |
|
| 2020 |
Shen L, Pelletier J. General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation. International Journal of Molecular Sciences. 21. PMID 32575790 DOI: 10.3390/Ijms21124402 |
0.388 |
|
| 2020 |
Xue Y, Zhu X, Meehan B, Venneti S, Martinez D, Morin G, Itoua Maïga R, Chen H, Papadakis AI, Johnson RM, O'Sullivan MJ, Erdreich-Epstein A, Gotlieb WH, Park M, Judkins AR, ... Pelletier J, et al. SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors. The Journal of Pathology. PMID 32558936 DOI: 10.1002/Path.5493 |
0.338 |
|
| 2020 |
Cencic R, Naineni SK, Pugsley L, Senechal P, Sahni A, Pelletier J. A CRISPR-based Screen Links an Inhibitor of Nonsense-mediated Decay to eIF4A3 Target Engagement. Acs Chemical Biology. PMID 32401488 DOI: 10.1021/Acschembio.0C00253 |
0.399 |
|
| 2020 |
Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Research. PMID 32282904 DOI: 10.1093/Nar/Gkaa222 |
0.359 |
|
| 2020 |
Chu J, Zhang W, Cencic R, O'Connor PBF, Robert F, Devine WG, Selznick A, Henkel T, Merrick WC, Brown LE, Baranov PV, Porco JA, Pelletier J. Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Reports. PMID 32101697 DOI: 10.1016/J.Celrep.2020.02.002 |
0.346 |
|
| 2020 |
Naineni SK, Itoua Maiga R, Cencic R, Putnam AA, Amador LA, Rodriguez AD, Jankowsky E, Pelletier J. A Comparative Study of Small Molecules Targeting eIF4A. Rna (New York, N.Y.). PMID 32014999 DOI: 10.1261/Rna.072884.119 |
0.367 |
|
| 2020 |
Tauber D, Tauber G, Khong A, Van Treeck B, Pelletier J, Parker R. Modulation of RNA Condensation by the DEAD-Box Protein eIF4A. Cell. PMID 31928844 DOI: 10.1016/J.Cell.2019.12.031 |
0.327 |
|
| 2020 |
Lehman SL, Wechsler T, Schwartz KR, Wahba A, Brown LE, Porco JA, Pelletier J, Camphausen K, Tofilon PJ. Abstract 6507: Inhibition of the translation initiation factor eIF4A1 enhances tumor cell radiosensitivity Cancer Research. 80: 6507-6507. DOI: 10.1158/1538-7445.Am2020-6507 |
0.442 |
|
| 2019 |
Shen L, Pelletier J. Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products. Natural Product Reports. PMID 31782447 DOI: 10.1039/C9Np00052F |
0.406 |
|
| 2019 |
Chan K, Robert F, Oertlin C, Kapeller-Libermann D, Avizonis D, Gutierrez J, Handly-Santana A, Doubrovin M, Park J, Schoepfer C, Da Silva B, Yao M, Gorton F, Shi J, Thomas CJ, ... ... Pelletier J, et al. eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma. Nature Communications. 10: 5151. PMID 31723131 DOI: 10.1038/S41467-019-13086-5 |
0.31 |
|
| 2019 |
Chu J, Zhang W, Cencic R, Devine WG, Beglov D, Henkel T, Brown LE, Vajda S, Porco JA, Pelletier J. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors. Cell Chemical Biology. PMID 31519508 DOI: 10.1016/J.Chembiol.2019.08.008 |
0.343 |
|
| 2019 |
Kong T, Xue Y, Cencic R, Zhu X, Monast A, Fu Z, Pilon V, Sangwan V, Guiot MC, Foulkes WD, Porco JA, Park M, Pelletier J, Huang S. eIF4A inhibitors suppress cell cycle feedback response and acquired resistance to CDK4/6 inhibition in cancer. Molecular Cancer Therapeutics. PMID 31395685 DOI: 10.1158/1535-7163.Mct-19-0162 |
0.314 |
|
| 2019 |
Zhang W, Chu J, Cyr AM, Yueh H, Brown LE, Wang TT, Pelletier J, Porco JA. Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors. Journal of the American Chemical Society. PMID 31310112 DOI: 10.1021/Jacs.9B06446 |
0.352 |
|
| 2019 |
Pelletier J, Sonenberg N. The Organizing Principles of Eukaryotic Ribosome Recruitment. Annual Review of Biochemistry. 88: 307-335. PMID 31220979 DOI: 10.1146/Annurev-Biochem-013118-111042 |
0.375 |
|
| 2019 |
Li X, Zhu Q, Shi X, Cheng Y, Li X, Xu H, Duan X, Hsieh-Wilson LC, Chu J, Pelletier J, Ni M, Zheng Z, Li S, Yi W. O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30940748 DOI: 10.1073/Pnas.1813026116 |
0.369 |
|
| 2019 |
Steinberger J, Robert F, Hallé M, Williams DE, Cencic R, Sawhney N, Pelletier D, Williams P, Igarashi Y, Porco JA, Rodriguez AD, Kopp B, Bachmann B, Andersen RJ, Pelletier J. Tracing MYC Expression for Small Molecule Discovery. Cell Chemical Biology. PMID 30880156 DOI: 10.1016/J.Chembiol.2019.02.007 |
0.372 |
|
| 2019 |
Itoua Maïga R, Cencic R, Chu J, Waller DD, Brown LE, Devine WG, Zhang W, Sebag M, Porco JA, Pelletier J. Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation. Scientific Reports. 9: 1265. PMID 30718665 DOI: 10.1038/S41598-018-37666-5 |
0.404 |
|
| 2019 |
Xue Y, Meehan B, Macdonald E, Venneti S, Wang XQD, Witkowski L, Jelinic P, Kong T, Martinez D, Morin G, Firlit M, Abedini A, Johnson RM, Cencic R, Patibandla J, ... ... Pelletier J, et al. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary. Nature Communications. 10: 558. PMID 30718512 DOI: 10.1038/S41467-018-06958-9 |
0.344 |
|
| 2019 |
Hardy S, Kostantin E, Wang SJ, Hristova T, Galicia-Vázquez G, Baranov PV, Pelletier J, Tremblay ML. Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718434 DOI: 10.1073/Pnas.1815361116 |
0.369 |
|
| 2019 |
Lin YH, Forster M, Liang Y, Yu M, Wang H, Robert F, Langlais D, Pelletier J, Clare S, Nijnik A. USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B cell mediated immune response in a mouse model. Experimental Hematology. PMID 30639577 DOI: 10.1016/J.Exphem.2019.01.001 |
0.35 |
|
| 2019 |
Xu J, Wendel H, Pelletier J, Yao Z, Rosen N. Abstract B075: eIF4A regulates ERK activation by controlling the translation of DUSP6 Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B075 |
0.408 |
|
| 2018 |
Robert F, Pelletier J. Exploring the Impact of Single-Nucleotide Polymorphisms on Translation. Frontiers in Genetics. 9: 507. PMID 30425729 DOI: 10.3389/Fgene.2018.00507 |
0.311 |
|
| 2018 |
Cencic R, Pelletier J. A cautionary note on the use of cap analogue affinity resins. Analytical Biochemistry. 560: 24-29. PMID 30193929 DOI: 10.1016/J.Ab.2018.09.001 |
0.385 |
|
| 2018 |
Cramer Z, Sadek J, Vazquez GG, Di Marco S, Pause A, Pelletier J, Gallouzi IE. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways. Scientific Reports. 8: 8414. PMID 29849089 DOI: 10.1038/S41598-018-26625-9 |
0.352 |
|
| 2018 |
Picard-Jean F, Brand C, Tremblay-Létourneau M, Allaire A, Beaudoin MC, Boudreault S, Duval C, Rainville-Sirois J, Robert F, Pelletier J, Geiss BJ, Bisaillon M. 2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO. Plos One. 13: e0193804. PMID 29601584 DOI: 10.1371/Journal.Pone.0193804 |
0.345 |
|
| 2018 |
Katigbak A, Robert F, Paquet M, Pelletier J. Inducible Genome Editing with Conditional CRISPR/Cas9 Mice. G3 (Bethesda, Md.). PMID 29519936 DOI: 10.1534/G3.117.300327 |
0.304 |
|
| 2018 |
Ramon Y Cajal S, Castellvi J, Hümmer S, Peg V, Pelletier J, Sonenberg N. Beyond molecular tumor heterogeneity: protein synthesis takes control. Oncogene. PMID 29463861 DOI: 10.1038/S41388-018-0152-0 |
0.337 |
|
| 2018 |
Chu J, Pelletier J. Therapeutic Opportunities in Eukaryotic Translation. Cold Spring Harbor Perspectives in Biology. PMID 29440069 DOI: 10.1101/Cshperspect.A032995 |
0.363 |
|
| 2018 |
Zhang X, Bi C, Lu T, Yue T, Zhang W, Zhang X, Cheng W, Tian T, Lunning MA, Vose JM, Pelletier J, Porco JA, Tao J, Fu K. Targeting Oncoprotein Translation with Rocaglates in MYC-Driven Lymphoma Blood. 132: 38-38. DOI: 10.1182/Blood-2018-99-117659 |
0.401 |
|
| 2017 |
Chu J, Cajal SRY, Sonenberg N, Pelletier J. Eukaryotic initiation factor 4F-sidestepping resistance mechanisms arising from expression heterogeneity. Current Opinion in Genetics & Development. 48: 89-96. PMID 29169064 DOI: 10.1016/J.Gde.2017.11.002 |
0.337 |
|
| 2017 |
Könst ZA, Szklarski AR, Pellegrino S, Michalak SE, Meyer M, Zanette C, Cencic R, Nam S, Voora VK, Horne DA, Pelletier J, Mobley DL, Yusupova G, Yusupov M, Vanderwal CD. Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nature Chemistry. 9: 1140-1149. PMID 29064494 DOI: 10.1038/Nchem.2800 |
0.343 |
|
| 2017 |
Pike KA, Hatzihristidis T, Bussières-Marmen S, Robert F, Desai N, Miranda-Saavedra D, Pelletier J, Tremblay ML. TC-PTP regulates the IL-7 transcriptional response during murine early T cell development. Scientific Reports. 7: 13275. PMID 29038451 DOI: 10.1038/S41598-017-13673-W |
0.337 |
|
| 2017 |
Fok KL, Bose R, Sheng K, Chang CW, Katz-Egorov M, Culty M, Su S, Yang M, Ruan YC, Chan HC, Iavarone A, Lasorella A, Cencic R, Pelletier J, Nagano M, et al. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Endocrinology. PMID 28938460 DOI: 10.1210/En.2017-00396 |
0.302 |
|
| 2017 |
Penafuerte C, Feldhammer M, Mills JR, Vinette V, Pike KA, Hall A, Migon E, Karsenty G, Pelletier J, Zogopoulos G, Tremblay ML. Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNγ signaling. Oncoimmunology. 6: e1321185. PMID 28680757 DOI: 10.1080/2162402X.2017.1321185 |
0.318 |
|
| 2017 |
Carvalho A, Chu J, Meinguet C, Kiss R, Vandenbussche G, Masereel B, Wouters J, Kornienko A, Pelletier J, Mathieu V. Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesis. Data in Brief. 12: 546-551. PMID 28529967 DOI: 10.1016/J.Dib.2017.05.006 |
0.362 |
|
| 2017 |
Lee T, Pelletier J. Dependence of p53-deficient cells on the DHX9 DExH-box helicase. Oncotarget. PMID 28427210 DOI: 10.18632/Oncotarget.15889 |
0.356 |
|
| 2017 |
Carvalho A, Chu J, Meinguet C, Kiss R, Vandenbussche G, Masereel B, Wouters J, Kornienko A, Pelletier J, Mathieu V. A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis. European Journal of Pharmacology. PMID 28322844 DOI: 10.1016/J.Ejphar.2017.03.034 |
0.384 |
|
| 2017 |
Abbas YM, Laudenbach BT, Martínez-Montero S, Cencic R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar B. Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28251928 DOI: 10.1073/Pnas.1612444114 |
0.368 |
|
| 2016 |
Steinberger J, Chu J, Maïga RI, Sleiman K, Pelletier J. Developing anti-neoplastic biotherapeutics against eIF4F. Cellular and Molecular Life Sciences : Cmls. PMID 28004147 DOI: 10.1007/S00018-016-2430-8 |
0.308 |
|
| 2016 |
Katigbak A, Cencic R, Robert F, Sénécha P, Scuoppo C, Pelletier J. A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors. Scientific Reports. 6: 38968. PMID 27982060 DOI: 10.1038/Srep38968 |
0.316 |
|
| 2016 |
Chu J, Cargnello M, Topisirovic I, Pelletier J. Translation Initiation Factors: Reprogramming Protein Synthesis in Cancer. Trends in Cell Biology. PMID 27426745 DOI: 10.1016/J.Tcb.2016.06.005 |
0.398 |
|
| 2016 |
Chu J, Galicia-Vázquez G, Cencic R, Mills JR, Katigbak A, Porco JA, Pelletier J. CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A. Cell Reports. PMID 27239032 DOI: 10.1016/J.Celrep.2016.05.005 |
0.407 |
|
| 2016 |
Manteghi S, Gingras MC, Kharitidi D, Galarneau L, Marques M, Yan M, Cencic R, Robert F, Paquet M, Witcher M, Pelletier J, Pause A. Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer. Cell Reports. PMID 27210750 DOI: 10.1016/J.Celrep.2016.04.076 |
0.353 |
|
| 2016 |
Bohne F, Langer D, Martiné U, Eider CS, Cencic R, Begemann M, Elbracht M, Bülow L, Eggermann T, Zechner U, Pelletier J, Zabel BU, Enklaar T, Prawitt D. Kaiso mediates human ICR1 methylation maintenance and H19 transcriptional fine regulation. Clinical Epigenetics. 8: 47. PMID 27152123 DOI: 10.1186/S13148-016-0215-4 |
0.379 |
|
| 2016 |
Lee T, Pelletier J. The biology of DHX9 and its potential as a therapeutic target. Oncotarget. PMID 27034008 DOI: 10.18632/Oncotarget.8446 |
0.378 |
|
| 2016 |
Gandin V, Masvidal L, Hulea L, Gravel SP, Cargnello M, McLaughlan S, Cai Y, Balanathan P, Morita M, Rajakumar A, Furic L, Pollak M, Porco JA, St-Pierre J, Pelletier J, et al. nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs. Genome Research. PMID 26984228 DOI: 10.1101/Gr.197566.115 |
0.374 |
|
| 2016 |
Lee T, Paquet M, Larsson O, Pelletier J. Tumor cell survival dependence on the DHX9 DExH-box helicase. Oncogene. PMID 26973242 DOI: 10.1038/Onc.2016.52 |
0.423 |
|
| 2016 |
Belle JI, Petrov JC, Langlais D, Robert F, Cencic R, Shen S, Pelletier J, Gros P, Nijnik A. Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance. Cell Death and Differentiation. PMID 26768662 DOI: 10.1038/Cdd.2015.140 |
0.311 |
|
| 2015 |
Malina A, Cameron CJ, Robert F, Blanchette M, Dostie J, Pelletier J. PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing. Nature Communications. 6: 10124. PMID 26644285 DOI: 10.1038/Ncomms10124 |
0.319 |
|
| 2015 |
Chu J, Cencic R, Wang W, Porco JA, Pelletier J. Translation Inhibition by Rocaglates is Independent of eIF4E Phosphorylation Status. Molecular Cancer Therapeutics. PMID 26586722 DOI: 10.1158/1535-7163.Mct-15-0409 |
0.388 |
|
| 2015 |
Cencic R, Senechal P, Pelletier J. Establishment of a Primary Screening Assay for the DHX9 Helicase. Combinatorial Chemistry & High Throughput Screening. 18: 855-61. PMID 26477352 DOI: 10.2174/1386207318666151019093433 |
0.403 |
|
| 2015 |
Galicia-Vázquez G, Chu J, Pelletier J. eIF4AII is dispensable for miRNA-mediated gene silencing. Rna (New York, N.Y.). 21: 1826-33. PMID 26286746 DOI: 10.1261/Rna.052225.115 |
0.317 |
|
| 2015 |
González-Almela E, Sanz MA, García-Moreno M, Northcote P, Pelletier J, Carrasco L. Differential action of pateamine A on translation of genomic and subgenomic mRNAs from Sindbis virus. Virology. 484: 41-50. PMID 26057151 DOI: 10.1016/J.Virol.2015.05.002 |
0.359 |
|
| 2015 |
Andrei AZ, Hall A, Smith AL, Bascuñana C, Malina A, Connor A, Altinel-Omeroglu G, Huang S, Pelletier J, Huntsman D, Gallinger S, Omeroglu A, Metrakos P, Zogopoulos G. Increased in vitro and in vivo sensitivity of BRCA2-associated pancreatic cancer to the poly(ADP-ribose) polymerase-1/2 inhibitor BMN 673. Cancer Letters. 364: 8-16. PMID 25864590 DOI: 10.1016/J.Canlet.2015.04.003 |
0.32 |
|
| 2015 |
Methot SP, Litzler LC, Trajtenberg F, Zahn A, Robert F, Pelletier J, Buschiazzo A, Magor BG, Di Noia JM. Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm. The Journal of Experimental Medicine. 212: 581-96. PMID 25824822 DOI: 10.1084/Jem.20141157 |
0.332 |
|
| 2015 |
Bhat M, Robichaud N, Hulea L, Sonenberg N, Pelletier J, Topisirovic I. Targeting the translation machinery in cancer. Nature Reviews. Drug Discovery. 14: 261-78. PMID 25743081 DOI: 10.1038/Nrd4505 |
0.357 |
|
| 2015 |
Pelletier J, Graff J, Ruggero D, Sonenberg N. Targeting the eIF4F translation initiation complex: a critical nexus for cancer development. Cancer Research. 75: 250-63. PMID 25593033 DOI: 10.1158/0008-5472.Can-14-2789 |
0.385 |
|
| 2015 |
Chu J, Pelletier J. Targeting the eIF4A RNA helicase as an anti-neoplastic approach. Biochimica Et Biophysica Acta. 1849: 781-791. PMID 25234619 DOI: 10.1016/J.Bbagrm.2014.09.006 |
0.413 |
|
| 2014 |
Malina A, Katigbak A, Cencic R, Maïga RI, Robert F, Miura H, Pelletier J. Adapting CRISPR/Cas9 for functional genomics screens. Methods in Enzymology. 546: 193-213. PMID 25398342 DOI: 10.1016/B978-0-12-801185-0.00010-6 |
0.314 |
|
| 2014 |
Fukao A, Mishima Y, Takizawa N, Oka S, Imataka H, Pelletier J, Sonenberg N, Thoma C, Fujiwara T. MicroRNAs trigger dissociation of eIF4AI and eIF4AII from target mRNAs in humans. Molecular Cell. 56: 79-89. PMID 25280105 DOI: 10.1016/J.Molcel.2014.09.005 |
0.384 |
|
| 2014 |
Cencic R, Miura H, Malina A, Robert F, Ethier S, Schmeing TM, Dostie J, Pelletier J. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage. Plos One. 9: e109213. PMID 25275497 DOI: 10.1371/Journal.Pone.0109213 |
0.346 |
|
| 2014 |
Robert F, Roman W, Bramoullé A, Fellmann C, Roulston A, Shustik C, Porco JA, Shore GC, Sebag M, Pelletier J. Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 111: 13421-6. PMID 25197055 DOI: 10.1073/Pnas.1402650111 |
0.401 |
|
| 2014 |
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, ... ... Pelletier J, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 513: 65-70. PMID 25079319 DOI: 10.1038/Nature13485 |
0.416 |
|
| 2014 |
Lee T, Di Paola D, Malina A, Mills JR, Kreps A, Grosse F, Tang H, Zannis-Hadjopoulos M, Larsson O, Pelletier J. Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. The Journal of Biological Chemistry. 289: 22798-814. PMID 24990949 DOI: 10.1074/Jbc.M114.568535 |
0.334 |
|
| 2014 |
Sun Y, Atas E, Lindqvist LM, Sonenberg N, Pelletier J, Meller A. Single-molecule kinetics of the eukaryotic initiation factor 4AI upon RNA unwinding. Structure (London, England : 1993). 22: 941-8. PMID 24909782 DOI: 10.1016/J.Str.2014.04.014 |
0.312 |
|
| 2014 |
Dow LE, Nasr Z, Saborowski M, Ebbesen SH, Manchado E, Tasdemir N, Lee T, Pelletier J, Lowe SW. Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice. Plos One. 9: e95236. PMID 24743474 DOI: 10.1371/Journal.Pone.0095236 |
0.35 |
|
| 2014 |
Shin U, Williams DE, Kozakov D, Hall DR, Beglov D, Vajda S, Andersen RJ, Pelletier J. Stimulators of translation identified during a small molecule screening campaign. Analytical Biochemistry. 447: 6-14. PMID 24513115 DOI: 10.1016/J.Ab.2013.10.026 |
0.349 |
|
| 2014 |
Galicia-Vázquez G, Di Marco S, Lian XJ, Ma JF, Gallouzi IE, Pelletier J. Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation. Plos One. 9: e87237. PMID 24466343 DOI: 10.1371/Journal.Pone.0087237 |
0.392 |
|
| 2014 |
Saborowski M, Saborowski A, Morris JP, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. A modular and flexible ESC-based mouse model of pancreatic cancer. Genes & Development. 28: 85-97. PMID 24395249 DOI: 10.1101/Gad.232082.113 |
0.317 |
|
| 2014 |
Martineau Y, Azar R, Müller D, Lasfargues C, El Khawand S, Anesia R, Pelletier J, Bousquet C, Pyronnet S. Pancreatic tumours escape from translational control through 4E-BP1 loss. Oncogene. 33: 1367-74. PMID 23563181 DOI: 10.1038/Onc.2013.100 |
0.37 |
|
| 2014 |
Totten S, Gaucher D, Morin RD, Assouline S, Connors JM, Marra MA, Scott DW, Gascoyne RD, Pelletier J, Mann KK, Johnson N. FAS Mutations Accelerate Lymphoma Growth and Induce Therapeutic Resistance Blood. 124: 3018-3018. DOI: 10.1182/Blood.V124.21.3018.3018 |
0.301 |
|
| 2013 |
Malina A, Mills JR, Cencic R, Yan Y, Fraser J, Schippers LM, Paquet M, Dostie J, Pelletier J. Repurposing CRISPR/Cas9 for in situ functional assays. Genes & Development. 27: 2602-14. PMID 24298059 DOI: 10.1101/Gad.227132.113 |
0.343 |
|
| 2013 |
Nasr Z, Dow LE, Paquet M, Chu J, Ravindar K, Somaiah R, Deslongchamps P, Porco JA, Lowe SW, Pelletier J. Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia. Bmc Pharmacology & Toxicology. 14: 58. PMID 24219888 DOI: 10.1186/2050-6511-14-58 |
0.371 |
|
| 2013 |
Boissonneault KR, Henningsen BM, Bates SS, Robertson DL, Milton S, Pelletier J, Hogan DA, Housman DE. Gene expression studies for the analysis of domoic acid production in the marine diatom Pseudo-nitzschia multiseries. Bmc Molecular Biology. 14: 25. PMID 24180290 DOI: 10.1186/1471-2199-14-25 |
0.322 |
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| 2013 |
Li Q, Makri A, Lu Y, Marchand L, Grabs R, Rousseau M, Ounissi-Benkalha H, Pelletier J, Robert F, Harmsen E, Hudson TJ, Pastinen T, Polychronakos C, Qu HQ. Genome-wide search for exonic variants affecting translational efficiency. Nature Communications. 4: 2260. PMID 23900168 DOI: 10.1038/Ncomms3260 |
0.361 |
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| 2013 |
Cencic R, Robert F, Galicia-Vázquez G, Malina A, Ravindar K, Somaiah R, Pierre P, Tanaka J, Deslongchamps P, Pelletier J. Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A. Blood Cancer Journal. 3: e128. PMID 23872707 DOI: 10.1038/Bcj.2013.25 |
0.394 |
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| 2013 |
Robert F, Pelletier J. Perturbations of RNA helicases in cancer. Wiley Interdisciplinary Reviews. Rna. 4: 333-49. PMID 23658027 DOI: 10.1002/Wrna.1163 |
0.355 |
|
| 2013 |
Sadlish H, Galicia-Vazquez G, Paris CG, Aust T, Bhullar B, Chang L, Helliwell SB, Hoepfner D, Knapp B, Riedl R, Roggo S, Schuierer S, Studer C, Porco JA, Pelletier J, et al. Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex. Acs Chemical Biology. 8: 1519-27. PMID 23614532 DOI: 10.1021/Cb400158T |
0.406 |
|
| 2013 |
Zhao WT, Zhou CF, Li XB, Zhang YF, Fan L, Pelletier J, Fang J. The von Hippel-Lindau protein pVHL inhibits ribosome biogenesis and protein synthesis. The Journal of Biological Chemistry. 288: 16588-97. PMID 23612971 DOI: 10.1074/Jbc.M113.455121 |
0.388 |
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| 2013 |
Mills JR, Malina A, Lee T, Di Paola D, Larsson O, Miething C, Grosse F, Tang H, Zannis-Hadjopoulos M, Lowe SW, Pelletier J. RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model. Blood. 121: 3402-12. PMID 23440244 DOI: 10.1182/Blood-2012-06-434365 |
0.357 |
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| 2013 |
Cencic R, Pelletier J. Throwing a monkey wrench in the motor: targeting DExH/D box proteins with small molecule inhibitors. Biochimica Et Biophysica Acta. 1829: 894-903. PMID 23385390 DOI: 10.1016/J.Bbagrm.2013.01.008 |
0.363 |
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| 2013 |
Garcia-Moreno M, Sanz MA, Pelletier J, Carrasco L. Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic mRNA in vertebrate and invertebrate host cells. Cellular Microbiology. 15: 823-40. PMID 23189929 DOI: 10.1111/Cmi.12079 |
0.339 |
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| 2013 |
Hoeffer CA, Santini E, Ma T, Arnold EC, Whelan AM, Wong H, Pierre P, Pelletier J, Klann E. Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation. Journal of Neurophysiology. 109: 68-76. PMID 23054596 DOI: 10.1152/Jn.00342.2012 |
0.324 |
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| 2013 |
Roulston A, Bernier C, Nguyen M, Ertel F, Robert F, Bellomo M, Huang XF, Bramoullé A, Gravel M, Sebag M, Pelletier J, Shore G. Abstract B17: Dexamethasone synthetic lethal screens uncover two potential combination therapies for the treatment of multiple myeloma Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B17 |
0.357 |
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| 2012 |
Scuoppo C, Miething C, Lindqvist L, Reyes J, Ruse C, Appelmann I, Yoon S, Krasnitz A, Teruya-Feldstein J, Pappin D, Pelletier J, Lowe SW. A tumour suppressor network relying on the polyamine-hypusine axis. Nature. 487: 244-8. PMID 22722845 DOI: 10.1038/Nature11126 |
0.385 |
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| 2012 |
Cencic R, Galicia-Vázquez G, Pelletier J. Inhibitors of translation targeting eukaryotic translation initiation factor 4A. Methods in Enzymology. 511: 437-61. PMID 22713332 DOI: 10.1016/B978-0-12-396546-2.00020-6 |
0.366 |
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| 2012 |
Galicia-Vázquez G, Cencic R, Robert F, Agenor AQ, Pelletier J. A cellular response linking eIF4AI activity to eIF4AII transcription. Rna (New York, N.Y.). 18: 1373-84. PMID 22589333 DOI: 10.1261/Rna.033209.112 |
0.447 |
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| 2012 |
Lin CJ, Nasr Z, Premsrirut PK, Porco JA, Hippo Y, Lowe SW, Pelletier J. Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis. Cell Reports. 1: 325-33. PMID 22573234 DOI: 10.1016/J.Celrep.2012.02.010 |
0.37 |
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| 2012 |
Malina A, Mills JR, Pelletier J. Emerging therapeutics targeting mRNA translation. Cold Spring Harbor Perspectives in Biology. 4: a012377. PMID 22474009 DOI: 10.1101/Cshperspect.A012377 |
0.389 |
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| 2012 |
Sun Y, Atas E, Lindqvist L, Sonenberg N, Pelletier J, Meller A. The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase. Nucleic Acids Research. 40: 6199-207. PMID 22457067 DOI: 10.1093/Nar/Gks278 |
0.377 |
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| 2012 |
Lee T, Pelletier J. Eukaryotic initiation factor 4F: a vulnerability of tumor cells. Future Medicinal Chemistry. 4: 19-31. PMID 22168162 DOI: 10.4155/Fmc.11.150 |
0.419 |
|
| 2012 |
Robert F, Mills JR, Agenor A, Wang D, DiMarco S, Cencic R, Tremblay ML, Gallouzi IE, Hekimi S, Wing SS, Pelletier J. Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival. Cancer Research. 72: 747-56. PMID 22158946 DOI: 10.1158/0008-5472.Can-11-2739 |
0.332 |
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| 2012 |
Rodrigo CM, Cencic R, Roche SP, Pelletier J, Porco JA. Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies. Journal of Medicinal Chemistry. 55: 558-62. PMID 22128783 DOI: 10.1021/Jm201263K |
0.333 |
|
| 2011 |
Schatz JH, Oricchio E, Wolfe AL, Jiang M, Linkov I, Maragulia J, Shi W, Zhang Z, Rajasekhar VK, Pagano NC, Porco JA, Teruya-Feldstein J, Rosen N, Zelenetz AD, Pelletier J, et al. Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma. The Journal of Experimental Medicine. 208: 1799-807. PMID 21859846 DOI: 10.1084/Jem.20110846 |
0.338 |
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| 2011 |
Kozakov D, Hall DR, Chuang GY, Cencic R, Brenke R, Grove LE, Beglov D, Pelletier J, Whitty A, Vajda S. Structural conservation of druggable hot spots in protein-protein interfaces. Proceedings of the National Academy of Sciences of the United States of America. 108: 13528-33. PMID 21808046 DOI: 10.1073/Pnas.1101835108 |
0.329 |
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| 2011 |
Cencic R, Desforges M, Hall DR, Kozakov D, Du Y, Min J, Dingledine R, Fu H, Vajda S, Talbot PJ, Pelletier J. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. Journal of Virology. 85: 6381-9. PMID 21507972 DOI: 10.1128/Jvi.00078-11 |
0.384 |
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| 2011 |
Dauber B, Pelletier J, Smiley JR. The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner. Journal of Virology. 85: 5363-73. PMID 21430045 DOI: 10.1128/Jvi.00115-11 |
0.359 |
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| 2011 |
Malina A, Cencic R, Pelletier J. Targeting translation dependence in cancer. Oncotarget. 2: 76-88. PMID 21378410 DOI: 10.18632/Oncotarget.218 |
0.326 |
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| 2011 |
Konicek BW, Stephens JR, McNulty AM, Robichaud N, Peery RB, Dumstorf CA, Dowless MS, Iversen PW, Parsons S, Ellis KE, McCann DJ, Pelletier J, Furic L, Yingling JM, Stancato LF, et al. Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. Cancer Research. 71: 1849-57. PMID 21233335 DOI: 10.1158/0008-5472.Can-10-3298 |
0.328 |
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| 2011 |
Takacs JE, Neary TB, Ingolia NT, Saini AK, Martin-Marcos P, Pelletier J, Hinnebusch AG, Lorsch JR. Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery. Rna (New York, N.Y.). 17: 439-52. PMID 21220547 DOI: 10.1261/Rna.2475211 |
0.362 |
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| 2011 |
Cencic R, Hall DR, Robert F, Du Y, Min J, Li L, Qui M, Lewis I, Kurtkaya S, Dingledine R, Fu H, Kozakov D, Vajda S, Pelletier J. Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F. Proceedings of the National Academy of Sciences of the United States of America. 108: 1046-51. PMID 21191102 DOI: 10.1073/Pnas.1011477108 |
0.391 |
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| 2011 |
Huang SX, Yu Z, Robert F, Zhao LX, Jiang Y, Duan Y, Pelletier J, Shen B. Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes Streptomyces sps. YIM56132 and YIM56141. The Journal of Antibiotics. 64: 163-6. PMID 21139626 DOI: 10.1038/Ja.2010.150 |
0.302 |
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| 2011 |
Sun Y, Atas E, Lindqvist L, Pelletier J, Sonenberg N, Meller A. Single-Molecule Studies of the Effects of Small Compounds on the Activity of Translation Initiation Factor eIF4A Biophysical Journal. 100: 192a. DOI: 10.1016/J.Bpj.2010.12.1266 |
0.386 |
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| 2010 |
Lindqvist L, Robert F, Merrick W, Kakeya H, Fraser C, Osada H, Pelletier J. Inhibition of translation by cytotrienin A - A member of the ansamycin family Rna. 16: 2404-2413. PMID 20943818 DOI: 10.1261/Rna.2307710 |
0.371 |
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| 2010 |
Ravindar K, Reddy MS, Lindqvist L, Pelletier J, Deslongchamps P. Efficient synthetic approach to potent antiproliferative agent hippuristanol via Hg(II)-catalyzed spiroketalization. Organic Letters. 12: 4420-3. PMID 20828120 DOI: 10.1021/Ol1019663 |
0.316 |
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| 2010 |
Bélanger F, Stepinski J, Darzynkiewicz E, Pelletier J. Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase. The Journal of Biological Chemistry. 285: 33037-44. PMID 20713356 DOI: 10.1074/Jbc.M110.155283 |
0.368 |
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| 2010 |
Roche SP, Cencic R, Pelletier J, Porco JA. Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation. Angewandte Chemie (International Ed. in English). 49: 6533-8. PMID 20687060 DOI: 10.1002/Anie.201003212 |
0.304 |
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| 2010 |
Van Goietsenoven G, Hutton J, Becker JP, Lallemand B, Robert F, Lefranc F, Pirker C, Vandenbussche G, Van Antwerpen P, Evidente A, Berger W, Prévost M, Pelletier J, Kiss R, Kinzy TG, et al. Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4575-84. PMID 20643906 DOI: 10.1096/Fj.10-162263 |
0.33 |
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| 2010 |
Deleavey GF, Watts JK, Alain T, Robert F, Kalota A, Aishwarya V, Pelletier J, Gewirtz AM, Sonenberg N, Damha MJ. Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing. Nucleic Acids Research. 38: 4547-57. PMID 20413581 DOI: 10.1093/Nar/Gkq181 |
0.371 |
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| 2010 |
Lin CJ, Robert F, Sukarieh R, Michnick S, Pelletier J. The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling. Cancer Research. 70: 3199-208. PMID 20354178 DOI: 10.1158/0008-5472.Can-09-4072 |
0.357 |
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| 2010 |
Sukarieh R, Sonenberg N, Pelletier J. Nuclear assortment of eIF4E coincides with shut-off of host protein synthesis upon poliovirus infection. The Journal of General Virology. 91: 1224-8. PMID 20053821 DOI: 10.1099/Vir.0.018069-0 |
0.357 |
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| 2010 |
Cencic R, Carrier M, Trnkus A, Porco JA, Minden M, Pelletier J. Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells. Leukemia Research. 34: 535-41. PMID 19726085 DOI: 10.1016/J.Leukres.2009.07.043 |
0.33 |
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| 2010 |
Roman W, Cencic R, Huang X, Porco J, Pelletier J, Shustik C, Sebag M. Inhibiting Translation as a Novel Strategy to Target Multiple Myeloma Blood. 116: 2995-2995. DOI: 10.1182/Blood.V116.21.2995.2995 |
0.329 |
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| 2010 |
Atas E, Sun Y, Lindqvist L, Pelletier J, Meller A. Single Molecule Studies Revealing the Dynamics of RNA Helicase eIF4A Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.076 |
0.371 |
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| 2009 |
Lindqvist L, Pelletier J. Inhibitors of translation initiation as cancer therapeutics. Future Medicinal Chemistry. 1: 1709-22. PMID 21425987 DOI: 10.4155/Fmc.09.122 |
0.364 |
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| 2009 |
Livingstone M, Larsson O, Sukarieh R, Pelletier J, Sonenberg N. A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. Chemistry & Biology. 16: 1240-9. PMID 20064434 DOI: 10.1016/J.Chembiol.2009.11.010 |
0.307 |
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| 2009 |
Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, et al. Target identification using drug affinity responsive target stability (DARTS). Proceedings of the National Academy of Sciences of the United States of America. 106: 21984-9. PMID 19995983 DOI: 10.1073/Pnas.0910040106 |
0.313 |
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| 2009 |
Lin CJ, Malina A, Pelletier J. c-Myc and eIF4F constitute a feedforward loop that regulates cell growth: implications for anticancer therapy. Cancer Research. 69: 7491-4. PMID 19773439 DOI: 10.1158/0008-5472.Can-09-0813 |
0.342 |
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| 2009 |
Robert F, Pelletier J. Translation initiation: a critical signalling node in cancer. Expert Opinion On Therapeutic Targets. 13: 1279-93. PMID 19705976 DOI: 10.1517/14728220903241625 |
0.361 |
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| 2009 |
Lin CJ, Sukarieh R, Pelletier J. Silibinin inhibits translation initiation: implications for anticancer therapy. Molecular Cancer Therapeutics. 8: 1606-12. PMID 19509268 DOI: 10.1158/1535-7163.Mct-08-1152 |
0.389 |
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| 2009 |
Robert F, Carrier M, Rawe S, Chen S, Lowe S, Pelletier J. Altering chemosensitivity by modulating translation elongation. Plos One. 4: e5428. PMID 19412536 DOI: 10.1371/Journal.Pone.0005428 |
0.333 |
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| 2009 |
Cencic R, Carrier M, Galicia-Vázquez G, Bordeleau ME, Sukarieh R, Bourdeau A, Brem B, Teodoro JG, Greger H, Tremblay ML, Porco JA, Pelletier J. Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. Plos One. 4: e5223. PMID 19401772 DOI: 10.1371/Journal.Pone.0005223 |
0.356 |
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| 2009 |
Dehbi M, Moeck G, Arhin FF, Bauda P, Bergeron D, Kwan T, Liu J, McCarty J, Dubow M, Pelletier J. Inhibition of transcription in Staphylococcus aureus by a primary sigma factor-binding polypeptide from phage G1. Journal of Bacteriology. 191: 3763-71. PMID 19376864 DOI: 10.1128/Jb.00241-09 |
0.411 |
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| 2009 |
Mokas S, Mills JR, Garreau C, Fournier MJ, Robert F, Arya P, Kaufman RJ, Pelletier J, Mazroui R. Uncoupling stress granule assembly and translation initiation inhibition. Molecular Biology of the Cell. 20: 2673-83. PMID 19369421 DOI: 10.1091/Mbc.E08-10-1061 |
0.381 |
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| 2009 |
Beutler JA, Kang MI, Robert F, Clement JA, Pelletier J, Colburn NH, McKee TC, Goncharova E, McMahon JB, Henrich CJ. Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. Journal of Natural Products. 72: 503-6. PMID 19199792 DOI: 10.1021/Np800732N |
0.333 |
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| 2009 |
Gravel M, Robert F, Kottis V, Gallouzi IE, Pelletier J, Braun PE. 2′,3′-cyclic nucleotide 3′-phosphodiesterase: A novel RNA-binding protein that inhibits protein synthesis Journal of Neuroscience Research. 87: 1069-1079. PMID 19021295 DOI: 10.1002/Jnr.21939 |
0.39 |
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| 2009 |
Galicia-Vázquez G, Lindqvist L, Wang X, Harvey I, Liu J, Pelletier J. High-throughput assays probing protein-RNA interactions of eukaryotic translation initiation factors. Analytical Biochemistry. 384: 180-8. PMID 18926791 DOI: 10.1016/J.Ab.2008.09.037 |
0.397 |
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| 2009 |
Atas E, Sun Y, Lindqvist L, Pelletier J, Meller A. Deciphering the Mechanism of RNA helicase eIF4A in Translation Initiation Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2121 |
0.393 |
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| 2008 |
Mavrakis KJ, Zhu H, Silva RL, Mills JR, Teruya-Feldstein J, Lowe SW, Tam W, Pelletier J, Wendel HG. Tumorigenic activity and therapeutic inhibition of Rheb GTPase. Genes & Development. 22: 2178-88. PMID 18708578 DOI: 10.1101/Gad.1690808 |
0.376 |
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| 2008 |
Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J. mTORC1 promotes survival through translational control of Mcl-1. Proceedings of the National Academy of Sciences of the United States of America. 105: 10853-8. PMID 18664580 DOI: 10.1073/Pnas.0804821105 |
0.363 |
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| 2008 |
Lin CJ, Cencic R, Mills JR, Robert F, Pelletier J. c-Myc and eIF4F are components of a feedforward loop that links transcription and translation. Cancer Research. 68: 5326-34. PMID 18593934 DOI: 10.1158/0008-5472.Can-07-5876 |
0.402 |
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| 2008 |
Bordeleau ME, Robert F, Gerard B, Lindqvist L, Chen SM, Wendel HG, Brem B, Greger H, Lowe SW, Porco JA, Pelletier J. Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model. The Journal of Clinical Investigation. 118: 2651-60. PMID 18551192 DOI: 10.1172/Jci34753 |
0.404 |
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| 2008 |
Rong L, Livingstone M, Sukarieh R, Petroulakis E, Gingras AC, Crosby K, Smith B, Polakiewicz RD, Pelletier J, Ferraiuolo MA, Sonenberg N. Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. Rna (New York, N.Y.). 14: 1318-27. PMID 18515545 DOI: 10.1261/Rna.950608 |
0.335 |
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| 2008 |
Lindqvist L, Imataka H, Pelletier J. Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking. Rna (New York, N.Y.). 14: 960-9. PMID 18367715 DOI: 10.1261/Rna.971208 |
0.372 |
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| 2008 |
Lindqvist L, Oberer M, Reibarkh M, Cencic R, Bordeleau ME, Vogt E, Marintchev A, Tanaka J, Fagotto F, Altmann M, Wagner G, Pelletier J. Selective pharmacological targeting of a DEAD box RNA helicase. Plos One. 3: e1583. PMID 18270573 DOI: 10.1371/Journal.Pone.0001583 |
0.39 |
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| 2007 |
Wendel HG, Silva RL, Malina A, Mills JR, Zhu H, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Teruya-Feldstein J, Pelletier J, Lowe SW. Dissecting eIF4E action in tumorigenesis. Genes & Development. 21: 3232-7. PMID 18055695 DOI: 10.1101/Gad.1604407 |
0.411 |
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| 2007 |
Cencic R, Robert F, Pelletier J. Identifying small molecule inhibitors of eukaryotic translation initiation. Methods in Enzymology. 431: 269-302. PMID 17923239 DOI: 10.1016/S0076-6879(07)31013-6 |
0.383 |
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| 2007 |
Kazemi S, Mounir Z, Baltzis D, Raven JF, Wang S, Krishnamoorthy JL, Pluquet O, Pelletier J, Koromilas AE. A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway. Molecular Biology of the Cell. 18: 3635-44. PMID 17596516 DOI: 10.1091/Mbc.E07-01-0053 |
0.325 |
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| 2007 |
Akimitsu N, Tanaka J, Pelletier J. Translation of nonSTOP mRNA is repressed post-initiation in mammalian cells. The Embo Journal. 26: 2327-38. PMID 17446866 DOI: 10.1038/Sj.Emboj.7601679 |
0.348 |
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| 2007 |
Cencic R, Yan Y, Pelletier J. Homogenous time resolved fluorescence assay to identify modulators of cap-dependent translation initiation. Combinatorial Chemistry & High Throughput Screening. 10: 181-8. PMID 17346117 DOI: 10.2174/138620707780126688 |
0.375 |
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| 2007 |
Watts JK, Choubdar N, Sadalapure K, Robert F, Wahba AS, Pelletier J, Pinto BM, Damha MJ. 2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity. Nucleic Acids Research. 35: 1441-51. PMID 17284457 DOI: 10.1093/Nar/Gkl1153 |
0.323 |
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| 2007 |
Bordeleau ME, Cencic R, Lindqvist L, Oberer M, Northcote P, Wagner G, Pelletier J. RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation. Chemistry & Biology. 13: 1287-95. PMID 17185224 DOI: 10.1016/J.Chembiol.2006.10.005 |
0.361 |
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| 2006 |
Spevak CC, Park EH, Geballe AP, Pelletier J, Sachs MS. her-2 upstream open reading frame effects on the use of downstream initiation codons. Biochemical and Biophysical Research Communications. 350: 834-41. PMID 17045969 DOI: 10.1016/J.Bbrc.2006.09.128 |
0.41 |
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| 2006 |
Robert F, Kapp LD, Khan SN, Acker MG, Kolitz S, Kazemi S, Kaufman RJ, Merrick WC, Koromilas AE, Lorsch JR, Pelletier J. Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability. Molecular Biology of the Cell. 17: 4632-44. PMID 16928960 DOI: 10.1091/Mbc.E06-06-0478 |
0.311 |
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| 2006 |
Wendel HG, Malina A, Zhao Z, Zender L, Kogan SC, Cordon-Cardo C, Pelletier J, Lowe SW. Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Research. 66: 7639-46. PMID 16885364 DOI: 10.1158/0008-5472.Can-06-0419 |
0.309 |
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| 2006 |
Mazroui R, Sukarieh R, Bordeleau ME, Kaufman RJ, Northcote P, Tanaka J, Gallouzi I, Pelletier J. Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation Molecular Biology of the Cell. 17: 4212-4219. PMID 16870703 DOI: 10.1091/Mbc.E06-04-0318 |
0.338 |
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| 2006 |
Chaudhry Y, Nayak A, Bordeleau ME, Tanaka J, Pelletier J, Belsham GJ, Roberts LO, Goodfellow IG. Caliciviruses differ in their functional requirements for eIF4F components. The Journal of Biological Chemistry. 281: 25315-25. PMID 16835235 DOI: 10.1074/Jbc.M602230200 |
0.365 |
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| 2006 |
Arhin F, Bélanger O, Ciblat S, Dehbi M, Delorme D, Dietrich E, Dixit D, Lafontaine Y, Lehoux D, Liu J, McKay GA, Moeck G, Reddy R, Rose Y, Srikumar R, ... ... Pelletier J, et al. A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 14: 5812-32. PMID 16759869 DOI: 10.1016/J.Bmc.2006.05.035 |
0.33 |
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| 2006 |
Robert F, Gao HQ, Donia M, Merrick WC, Hamann MT, Pelletier J. Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis. Rna (New York, N.Y.). 12: 717-25. PMID 16540697 DOI: 10.1261/Rna.2346806 |
0.361 |
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| 2006 |
Bordeleau ME, Mori A, Oberer M, Lindqvist L, Chard LS, Higa T, Belsham GJ, Wagner G, Tanaka J, Pelletier J. Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A. Nature Chemical Biology. 2: 213-20. PMID 16532013 DOI: 10.1038/Nchembio776 |
0.38 |
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| 2006 |
Petersen CP, Bordeleau ME, Pelletier J, Sharp PA. Short RNAs repress translation after initiation in mammalian cells. Molecular Cell. 21: 533-42. PMID 16483934 DOI: 10.1016/J.Molcel.2006.01.031 |
0.365 |
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| 2006 |
Park EH, Lee JM, Pelletier J. The Tie2 5′ untranslated region is inhibitory to 5′ end-mediated translation initiation Febs Letters. 580: 1309-1319. PMID 16457819 DOI: 10.1016/J.Febslet.2006.01.049 |
0.389 |
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| 2006 |
Torban E, Dziarmaga A, Iglesias D, Chu LL, Vassilieva T, Little M, Eccles M, Discenza M, Pelletier J, Goodyer P. PAX2 activates WNT4 expression during mammalian kidney development. The Journal of Biological Chemistry. 281: 12705-12. PMID 16368682 DOI: 10.1074/Jbc.M513181200 |
0.781 |
|
| 2005 |
Yan Y, Svitkin Y, Lee JM, Bisaillon M, Pelletier J. Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap. Rna. 11: 1238-1244. PMID 16043507 DOI: 10.1261/Rna.2930805 |
0.324 |
|
| 2005 |
Bordeleau ME, Matthews J, Wojnar JM, Lindqvist L, Novac O, Jankowsky E, Sonenberg N, Northcote P, Teesdale-Spittle P, Pelletier J. Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proceedings of the National Academy of Sciences of the United States of America. 102: 10460-5. PMID 16030146 DOI: 10.1073/Pnas.0504249102 |
0.383 |
|
| 2005 |
Park EH, Lee JM, Blais JD, Bell JC, Pelletier J. Internal translation initiation mediated by the angiogenic factor Tie2. The Journal of Biological Chemistry. 280: 20945-53. PMID 15802272 DOI: 10.1074/Jbc.M412744200 |
0.376 |
|
| 2005 |
Prawitt D, Enklaar T, Gärtner-Rupprecht B, Spangenberg C, Oswald M, Lausch E, Schmidtke P, Reutzel D, Fees S, Lucito R, Korzon M, Brozek I, Limon J, Housman DE, Pelletier J, et al. Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor. Proceedings of the National Academy of Sciences of the United States of America. 102: 4085-90. PMID 15743916 DOI: 10.1073/Pnas.0500037102 |
0.337 |
|
| 2005 |
Fukamiya N, Lee KH, Muhammad I, Murakami C, Okano M, Harvey I, Pelletier J. Structure-activity relationships of quassinoids for eukaryotic protein synthesis. Cancer Letters. 220: 37-48. PMID 15737686 DOI: 10.1016/J.Canlet.2004.04.023 |
0.34 |
|
| 2005 |
Malina A, Khan S, Carlson CB, Svitkin Y, Harvey I, Sonenberg N, Beal PA, Pelletier J. Inhibitory properties of nucleic acid-binding ligands on protein synthesis. Febs Letters. 579: 79-89. PMID 15620694 DOI: 10.1016/J.Febslet.2004.06.103 |
0.381 |
|
| 2004 |
Kumar R, Garneau P, Nguyen N, Lown JW, Pelletier J. Methionine sustituted polyamides are RNAse mimics that inhibit translation Journal of Drug Targeting. 12: 125-134. PMID 15203891 DOI: 10.1080/1061186042000220728 |
0.379 |
|
| 2004 |
Lee HJ, Kim S, Pelletier J, Kim J. Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src. Febs Letters. 564: 188-98. PMID 15094065 DOI: 10.1016/S0014-5793(04)00314-X |
0.347 |
|
| 2004 |
Wang B, Pelletier J, Massaad MJ, Herscovics A, Shore GC. The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Molecular and Cellular Biology. 24: 2767-78. PMID 15024066 DOI: 10.1128/Mcb.24.7.2767-2778.2004 |
0.323 |
|
| 2004 |
Discenza MT, Vaz D, Hassell JA, Pelletier J. Activation of the WT1 tumor suppressor gene promoter by Pea3. Febs Letters. 560: 183-91. PMID 14988020 DOI: 10.1016/S0014-5793(04)00104-8 |
0.777 |
|
| 2004 |
Chan J, Khan SN, Harvey I, Merrick W, Pelletier J. Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles. Rna (New York, N.Y.). 10: 528-43. PMID 14970397 DOI: 10.1261/Rna.5200204 |
0.353 |
|
| 2004 |
Discenza MT, Pelletier J. Insights into the physiological role of WT1 from studies of genetically modified mice. Physiological Genomics. 16: 287-300. PMID 14966251 DOI: 10.1152/Physiolgenomics.00164.2003 |
0.779 |
|
| 2004 |
Novac O, Guenier AS, Pelletier J. Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen. Nucleic Acids Research. 32: 902-15. PMID 14769948 DOI: 10.1093/Nar/Gkh235 |
0.369 |
|
| 2004 |
Liu J, Dehbi M, Moeck G, Arhin F, Bauda P, Bergeron D, Callejo M, Ferretti V, Ha N, Kwan T, McCarty J, Srikumar R, Williams D, Wu JJ, Gros P, ... Pelletier J, et al. Antimicrobial drug discovery through bacteriophage genomics. Nature Biotechnology. 22: 185-91. PMID 14716317 DOI: 10.1038/Nbt932 |
0.322 |
|
| 2003 |
Discenza MT, He S, Lee TH, Chu LL, Bolon B, Goodyer P, Eccles M, Pelletier J. WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2. Oncogene. 22: 8145-55. PMID 14603255 DOI: 10.1038/Sj.Onc.1206997 |
0.762 |
|
| 2002 |
Lee J, Park EH, Couture G, Harvey I, Garneau P, Pelletier J. An upstream open reading frame impedes translation of the huntingtin gene. Nucleic Acids Research. 30: 5110-9. PMID 12466534 DOI: 10.1093/Nar/Gkf664 |
0.415 |
|
| 2002 |
Carriere M, Vijayabaskar V, Applefield D, Harvey I, Garneau P, Lorsch J, Lapidot A, Pelletier J. Inhibition of protein synthesis by aminoglycoside-arginine conjugates. Rna (New York, N.Y.). 8: 1267-79. PMID 12403465 DOI: 10.1017/S1355838202029059 |
0.386 |
|
| 2002 |
Lee TH, Lwu S, Kim J, Pelletier J. Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor. The Journal of Biological Chemistry. 277: 44826-37. PMID 12239212 DOI: 10.1074/Jbc.M205667200 |
0.441 |
|
| 2002 |
Cai J, Daoud R, Alqawi O, Georges E, Pelletier J, Gros P. Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6). Biochemistry. 41: 8058-67. PMID 12069597 DOI: 10.1021/Bi012082P |
0.327 |
|
| 2002 |
Harvey I, Garneau P, Pelletier J. Inhibition of translation by RNA-small molecule interactions. Rna (New York, N.Y.). 8: 452-63. PMID 11991640 DOI: 10.1017/S135583820202633X |
0.392 |
|
| 2002 |
Harvey I, Garneau P, Pelletier J. Forced engagement of a RNA/protein complex by a chemical inducer of dimerization to modulate gene expression. Proceedings of the National Academy of Sciences of the United States of America. 99: 1882-7. PMID 11854489 DOI: 10.1073/Pnas.042693399 |
0.386 |
|
| 2001 |
Lee TH, Pelletier J. Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter. Physiological Genomics. 7: 187-200. PMID 11773605 DOI: 10.1152/Physiolgenomics.00046.2001 |
0.397 |
|
| 2001 |
Das M, Burge CB, Park E, Colinas J, Pelletier J. Assessment of the total number of human transcription units Genomics. 77: 71-78. PMID 11543635 DOI: 10.1006/Geno.2001.6620 |
0.341 |
|
| 2000 |
Kim J, Lee JM, Branton PE, Pelletier J. Modulation of EWS/WT1 activity by the v-Src protein tyrosine kinase Febs Letters. 474: 121-128. PMID 10838070 DOI: 10.1016/S0014-5793(00)01590-8 |
0.352 |
|
| 2000 |
Moffett P, Pelletier J. Different transcriptional properties of mSim-1 and mSim-2 Febs Letters. 466: 80-86. PMID 10648817 DOI: 10.1016/S0014-5793(99)01750-0 |
0.379 |
|
| 2000 |
Prawitt D, Enklaar T, Klemm G, Gärtner B, Spangenberg C, Winterpacht A, Higgins M, Pelletier J, Zabel B. Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression Human Molecular Genetics. 9: 203-216. PMID 10607831 DOI: 10.1093/Hmg/9.2.203 |
0.408 |
|
| 1999 |
Kim J, Lee JM, Branton PE, Pelletier J. Modification of EWS/WT1 functional properties by phosphorylation Proceedings of the National Academy of Sciences of the United States of America. 96: 14300-14305. PMID 10588700 DOI: 10.1073/Pnas.96.25.14300 |
0.348 |
|
| 1999 |
Lee TH, Moffett P, Pelletier J. The Wilms' tumor suppressor gene (wt1) product represses different functional classes of transcriptional activation domains. Nucleic Acids Research. 27: 2889-2897. PMID 10390530 DOI: 10.1093/Nar/27.14.2889 |
0.384 |
|
| 1999 |
Kim J, Prawitt D, Bardeesy N, Torban E, Vicaner C, Goodyer P, Zabel B, Pelletier J. The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation. Molecular and Cellular Biology. 19: 2289-99. PMID 10022915 DOI: 10.1128/Mcb.19.3.2289 |
0.437 |
|
| 1998 |
Chu LL, Rutteman GR, Kong JM, Ghahremani M, Schmeing M, Misdorp W, van Garderen E, Pelletier J. Genomic organization of the canine p53 gene and its mutational status in canine mammary neoplasia. Breast Cancer Research and Treatment. 50: 11-25. PMID 9802616 DOI: 10.1023/A:1006010526813 |
0.324 |
|
| 1998 |
Reece M, Prawitt D, Landers J, Kast C, Gros P, Housman D, Zabel BU, Pelletier J. Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules. Febs Letters. 433: 245-50. PMID 9744804 DOI: 10.1016/S0014-5793(98)00907-7 |
0.325 |
|
| 1998 |
Kim J, Lee K, Pelletier J. The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic properties. Oncogene. 16: 1973-9. PMID 9591781 DOI: 10.1038/Sj.Onc.1201716 |
0.362 |
|
| 1998 |
Dehbi M, Hiscott J, Pelletier J. Activation of the wt1 Wilms' tumor suppressor gene by NF-kappaB. Oncogene. 16: 2033-9. PMID 9572484 DOI: 10.1038/Sj.Onc.1201747 |
0.403 |
|
| 1998 |
Cooper PR, Smilinich NJ, Day CD, Nowak NJ, Reid LH, Pearsall RS, Reece M, Prawitt D, Landers J, Housman DE, Winterpacht A, Zabel BU, Pelletier J, Weissman BE, Shows TB, et al. Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. Genomics. 49: 38-51. PMID 9570947 DOI: 10.1006/Geno.1998.5221 |
0.401 |
|
| 1998 |
Kim J, Lee K, Pelletier J. The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein are functionally distinct. Oncogene. 16: 1021-30. PMID 9519876 DOI: 10.1038/Sj.Onc.1201616 |
0.363 |
|
| 1998 |
Bardeesy N, Pelletier J. Overlapping RNA and DNA binding domains of the wt1 tumor suppressor gene product. Nucleic Acids Research. 26: 1784-92. PMID 9512553 DOI: 10.1093/Nar/26.7.1784 |
0.418 |
|
| 1997 |
Torban E, Pelletier J, Goodyer P. F329L polymorphism in the human PAX8 gene. American Journal of Medical Genetics. 72: 186-7. PMID 9382140 DOI: 10.1002/(Sici)1096-8628(19971017)72:2<186::Aid-Ajmg11>3.0.Co;2-J |
0.313 |
|
| 1997 |
Discenza MT, Dehbi M, Pelletier J. Overlapping DNA recognition motifs between Sp1 and a novel trans-acting factor within the wt1 tumour suppressor gene promoter. Nucleic Acids Research. 25: 4314-22. PMID 9336463 DOI: 10.1093/Nar/25.21.4314 |
0.77 |
|
| 1997 |
Rodriguez P, Munroe D, Prawitt D, Chu LL, Bric E, Kim J, Reid LH, Davies C, Nakagama H, Loebbert R, Winterpacht A, Petruzzi MJ, Higgins MJ, Nowak N, Evans G, ... ... Pelletier J, et al. Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone. Genomics. 44: 253-65. PMID 9325046 DOI: 10.1006/Geno.1997.4868 |
0.395 |
|
| 1997 |
Vicanek C, Ferretti E, Goodyer C, Torban E, Moffett P, Pelletier J, Goodyer P. Regulation of renal EGF receptor expression is normal in Denys-Drash syndrome. Kidney International. 52: 614-9. PMID 9291179 DOI: 10.1038/Ki.1997.374 |
0.373 |
|
| 1997 |
Moffett P, Reece M, Pelletier J. The murine Sim-2 gene product inhibits transcription by active repression and functional interference Molecular and Cellular Biology. 17: 4933-4947. PMID 9271372 DOI: 10.1128/Mcb.17.9.4933 |
0.415 |
|
| 1996 |
Ghahremani M, Chan CB, Bistritzer T, Aladjem M, Tieder M, Pelletier J. A novel mutation H373Y in the Wilms' tumor suppressor gene, WT1, associated with Denys-Drash syndrome Human Heredity. 46: 336-338. PMID 8956030 DOI: 10.1159/000154374 |
0.317 |
|
| 1996 |
Fuqua JS, Sher ES, Perlman EJ, Urban MD, Ghahremani M, Pelletier J, Migeon CJ, Brown TR, Berkovitz GD. Abnormal gonadal differentiation in two subjects with ambiguous genitalia, Mullerian structures, and normally developed testes: evidence for a defect in gonadal ridge development. Human Genetics. 97: 506-11. PMID 8834252 DOI: 10.1007/Bf02267076 |
0.322 |
|
| 1996 |
Bruening W, Moffett P, Chia S, Heinrich G, Pelletier J. Identification of nuclear localization signals within the zinc fingers of the WT1 tumor suppressor gene product. Febs Letters. 393: 41-47. PMID 8804420 DOI: 10.1016/0014-5793(96)00853-8 |
0.382 |
|
| 1996 |
Moffett P, Dayo M, Reece M, McCormick MK, Pelletier J. Characterization of msim, a murine homologue of the Drosophila sim transcription factor Genomics. 35: 144-155. PMID 8661115 DOI: 10.1006/Geno.1996.0333 |
0.424 |
|
| 1996 |
Bruening W, Pelletier J. A Non-AUG Translational Initiation Event Generates Novel WT1 Isoforms Journal of Biological Chemistry. 271: 8646-8654. PMID 8621495 DOI: 10.1074/Jbc.271.15.8646 |
0.468 |
|
| 1996 |
Dehbi M, Pelletier J. PAX8-mediated activation of the wt1 tumor suppressor gene. The Embo Journal. 15: 4297-4306. DOI: 10.1002/J.1460-2075.1996.Tb00804.X |
0.434 |
|
| 1995 |
Nakagama H, Heinrich G, Pelletier J, Housman DE. Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product. Molecular and Cellular Biology. 15: 1489-98. PMID 7862142 DOI: 10.1128/Mcb.15.3.1489 |
0.341 |
|
| 1995 |
Gradi A, Tang-Wai R, McBride HM, Chu LL, Shore GC, Pelletier J. The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide. Biochimica Et Biophysica Acta. 1258: 228-33. PMID 7548191 DOI: 10.1016/0005-2760(95)00140-8 |
0.354 |
|
| 1995 |
Moffett P, Bruening W, Nakagama H, Bardeesy N, Housman D, Housman DE, Pelletier J. Antagonism of WT1 activity by protein self-association. Proceedings of the National Academy of Sciences of the United States of America. 92: 11105-9. PMID 7479946 DOI: 10.1073/Pnas.92.24.11105 |
0.394 |
|
| 1994 |
Varanasi R, Bardeesv N, Ghahremani M, Petruzzi MJ, Nowak N, Adam MA, Grundy P, Shows TB, Pelletier J. Fine structure analysis of the WT1 gene in sporadic Wilms tumors Proceedings of the National Academy of Sciences of the United States of America. 91: 3554-3558. PMID 8170946 DOI: 10.1073/Pnas.91.9.3554 |
0.357 |
|
| 1994 |
Bardeesy N, Falkoff D, Petruzzi M, Nowak N, Zabel B, Adam M, Aguiar MC, Grundy P, Shows T, Pelletier J. Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations. Nature Genetics. 7: 91-97. PMID 8075648 DOI: 10.1038/Ng0594-91 |
0.309 |
|
| 1994 |
Bruening W, Pelletier J. Denys-Drash syndrome: a role for the WT1 tumour suppressor gene in urogenital development Seminars in Developmental Biology. 5: 333-343. DOI: 10.1006/Sedb.1994.1042 |
0.345 |
|
| 1993 |
Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. WT-1 is required for early kidney development. Cell. 74: 679-91. PMID 8395349 DOI: 10.1016/0092-8674(93)90515-R |
0.364 |
|
| 1993 |
Bruening W, Gros P, Sato T, Stanimir J, Nakamura Y, Housman D, Pelletier J. Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors. Cancer Investigation. 11: 393-9. PMID 8324644 DOI: 10.3109/07357909309018871 |
0.322 |
|
| 1992 |
Haber DA, Timmers HT, Pelletier J, Sharp PA, Housman DE. A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 6010-4. PMID 1321431 DOI: 10.1073/Pnas.89.13.6010 |
0.393 |
|
| 1992 |
Bruening W, Bardeesy N, Silverman BL, Cohn RA, Machin GA, Aronson AJ, Housman D, Pelletier J. Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development. Nature Genetics. 1: 144-8. PMID 1302008 DOI: 10.1038/Ng0592-144 |
0.348 |
|
| 1991 |
Pelletier J, Brook JD, Housman DE. Assignment of two of the translation initiation factor-4E (EIF4EL1 and EIF4EL2) genes to human chromosomes 4 and 20. Genomics. 10: 1079-82. PMID 1916814 DOI: 10.1016/0888-7543(91)90203-Q |
0.342 |
|
| 1991 |
Buckler AJ, Pelletier J, Haber DA, Glaser T, Housman DE. Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development. Molecular and Cellular Biology. 11: 1707-12. PMID 1671709 DOI: 10.1128/Mcb.11.3.1707 |
0.416 |
|
| 1991 |
Haber DA, Sohn RL, Buckler AJ, Pelletier J, Call KM, Housman DE. Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proceedings of the National Academy of Sciences of the United States of America. 88: 9618-22. PMID 1658787 DOI: 10.1073/Pnas.88.21.9618 |
0.437 |
|
| 1991 |
Nicholson R, Pelletier J, Le SY, Sonenberg N. Structural and functional analysis of the ribosome landing pad of poliovirus type 2: in vivo translation studies. Journal of Virology. 65: 5886-94. PMID 1656077 DOI: 10.1128/Jvi.65.11.5886-5894.1991 |
0.337 |
|
| 1991 |
Pelletier J, Bruening W, Kashtan CE, Mauer SM, Manivel JC, Striegel JE, Houghton DC, Junien C, Habib R, Fouser L, Fine RN, Silverman BL, Haber DA, Housman D. Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. Cell. 67: 437-447. PMID 1655284 DOI: 10.1016/0092-8674(91)90194-4 |
0.326 |
|
| 1991 |
Pelletier J, Bruening W, Li FP, Haber DA, Glaser T, Housman DE. WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour. Nature. 353: 431-4. PMID 1654525 DOI: 10.1038/353431A0 |
0.349 |
|
| 1991 |
Pelletier J, Schalling M, Buckler AJ, Rogers A, Haber DA, Housman D. Expression of the Wilms' tumor gene WT1 in the murine urogenital system. Genes & Development. 5: 1345-56. PMID 1651275 DOI: 10.1101/Gad.5.8.1345 |
0.445 |
|
| 1990 |
Sonenberg N, Pelletier J. Poliovirus translation: a paradigm for a novel initiation mechanism. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 11: 128-32. PMID 2556117 DOI: 10.1002/Bies.950110504 |
0.375 |
|
| 1990 |
Altmann M, Blum S, Pelletier J, Sonenberg N, Wilson TM, Trachsel H. Translation initiation factor-dependent extracts from Saccharomyces cerevisiae. Biochimica Et Biophysica Acta. 1050: 155-9. PMID 2169890 DOI: 10.1016/0167-4781(90)90158-X |
0.351 |
|
| 1990 |
Pritchard-Jones K, Fleming S, Davidson D, Bickmore W, Porteous D, Gosden C, Bard J, Buckler A, Pelletier J, Housman D. The candidate Wilms' tumour gene is involved in genitourinary development. Nature. 346: 194-7. PMID 2164159 DOI: 10.1038/346194A0 |
0.379 |
|
| 1990 |
Haber DA, Buckler AJ, Glaser T, Call KM, Pelletier J, Sohn RL, Douglass EC, Housman DE. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell. 61: 1257-69. PMID 2163761 DOI: 10.1016/0092-8674(90)90690-G |
0.37 |
|
| 1990 |
Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J, Haber DA, Rose EA, Kral A, Yeger H, Lewis WH. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell. 60: 509-20. PMID 2154335 DOI: 10.1016/0092-8674(90)90601-A |
0.388 |
|
| 1989 |
Boylan MO, Pelletier J, Dhepagnon S, Trudel S, Sonenberg N, Meighen EA. Construction of a fused LuxAB gene by site-directed mutagenesis Journal of Bioluminescence and Chemiluminescence. 4: 310-316. PMID 2678919 DOI: 10.1002/Bio.1170040143 |
0.361 |
|
| 1988 |
Milburn SC, Pelletier J, Sonenberg N, Hershey JW. Identification of the 80-kDa protein that crosslinks to the cap structure of eukaryotic mRNAs as initiation factor eIF-4B. Archives of Biochemistry and Biophysics. 264: 348-50. PMID 3395129 DOI: 10.1016/0003-9861(88)90604-2 |
0.345 |
|
| 1988 |
Pelletier J, Sonenberg N. The involvement of mRNA secondary structure in protein synthesis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 576-81. PMID 3322328 DOI: 10.1139/O87-074 |
0.368 |
|
| 1988 |
Trono D, Pelletier J, Sonenberg N, Baltimore D. Translation in mammalian cells of a gene linked to the poliovirus 5' noncoding region. Science (New York, N.Y.). 241: 445-8. PMID 2839901 DOI: 10.1126/Science.2839901 |
0.408 |
|
| 1988 |
Pelletier J, Sonenberg N. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature. 334: 320-5. PMID 2839775 DOI: 10.1038/334320A0 |
0.342 |
|
| 1988 |
Pelletier J, Kaplan G, Racaniello VR, Sonenberg N. Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region Molecular and Cellular Biology. 8: 1103-1112. PMID 2835660 DOI: 10.1128/Mcb.8.3.1103 |
0.346 |
|
| 1987 |
Pelletier J, Nicholson R, Bassel-Duby R, Fields BN, Sonenberg N. Expression of reovirus type 3 (Dearing) sigma 1 and sigma s polypeptides in Escherichia coli. The Journal of General Virology. 135-45. PMID 3543215 DOI: 10.1099/0022-1317-68-1-135 |
0.337 |
|
| 1985 |
Sarkar G, Pelletier J, Bassel-Duby R, Jayasuriya A, Fields BN, Sonenberg N. Identification of a new polypeptide coded by reovirus gene S1. Journal of Virology. 54: 720-5. PMID 3999193 DOI: 10.1128/Jvi.54.3.720-725.1985 |
0.342 |
|
| 1985 |
Darveau A, Pelletier J, Sonenberg N. Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5' untranslated region Proceedings of the National Academy of Sciences of the United States of America. 82: 2315-2319. PMID 3857582 DOI: 10.1073/Pnas.82.8.2315 |
0.351 |
|
| 1985 |
Pelletier J, Sonenberg N. Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency. Cell. 40: 515-26. PMID 2982496 DOI: 10.1016/0092-8674(85)90200-4 |
0.387 |
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