Robert C. Landick - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Microbiology Biology, Genetics, Biochemistry
Website:
https://biochem.wisc.edu/faculty/landick

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hustmyer CM, Wolfe MB, Welch RA, Landick R. RfaH Counter-Silences Inhibition of Transcript Elongation by H-NS-StpA Nucleoprotein Filaments in Pathogenic Escherichia coli. Mbio. e0266222. PMID 36264101 DOI: 10.1128/mbio.02662-22  0.354
2022 Cao X, Boyaci H, Chen J, Bao Y, Landick R, Campbell EA. Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature. PMID 35388215 DOI: 10.1038/s41586-022-04545-z  0.445
2021 Dai W, Darst SA, Dunham CM, Landick R, Petsko G, Weixlbaumer A. Seeing gene expression in cells: the future of structural biology. Faculty Reviews. 10: 79. PMID 35146496 DOI: 10.12703/r-01-000004  0.313
2021 Palo MZ, Zhu J, Mishanina TV, Landick R. Conserved Trigger Loop Histidine of RNA Polymerase II Functions as a Positional Catalyst Primarily through Steric Effects. Biochemistry. 60: 3323-3336. PMID 34705427 DOI: 10.1021/acs.biochem.1c00528  0.404
2021 Bao Y, Landick R. Obligate movements of an active site-linked surface domain control RNA polymerase elongation and pausing via a Phe pocket anchor. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34470825 DOI: 10.1073/pnas.2101805118  0.374
2021 Landick R. Transcriptional Pausing as a Mediator of Bacterial Gene Regulation. Annual Review of Microbiology. PMID 34348029 DOI: 10.1146/annurev-micro-051721-043826  0.545
2021 Shiver AL, Osadnik H, Peters JM, Mooney RA, Wu PI, Henry KK, Braberg H, Krogan NJ, Hu JC, Landick R, Huang KC, Gross CA. Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. Molecular Cell. 81: 2201-2215.e9. PMID 34019789 DOI: 10.1016/j.molcel.2021.04.027  0.798
2021 Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ, Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw DE, Landick R, Darst SA, Campbell EA. Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33883267 DOI: 10.1073/pnas.2102516118  0.522
2021 Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ, Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw DE, Landick R, Darst SA, Campbell EA. Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Biorxiv : the Preprint Server For Biology. PMID 33758867 DOI: 10.1101/2021.03.13.435256  0.536
2020 Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, Darst SA, Campbell EA. The antibiotic sorangicin A inhibits promoter DNA unwinding in a rifampicin-resistant RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. PMID 33199626 DOI: 10.1073/pnas.2013706117  0.66
2020 Henry KK, Ross W, Myers KS, Lemmer KC, Vera JM, Landick R, Donohue TJ, Gourse RL. A majority of promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 33168725 DOI: 10.1073/pnas.2010087117  0.595
2020 Myers KS, Vera JM, Lemmer KC, Linz AM, Landick R, Noguera DR, Donohue TJ. Genome-Wide Identification of Transcription Start Sites in Two , Rhodobacter sphaeroides 2.4.1 and Novosphingobium aromaticivorans DSM 12444. Microbiology Resource Announcements. 9. PMID 32883797 DOI: 10.1128/MRA.00880-20  0.504
2020 Vera JM, Ghosh IN, Zhang Y, Hebert AS, Coon JJ, Landick R. Genome-Scale Transcription-Translation Mapping Reveals Features of Zymomonas mobilis Transcription Units and Promoters. Msystems. 5. PMID 32694125 DOI: 10.1128/mSystems.00250-20  0.401
2020 Harden TT, Herlambang KS, Chamberlain M, Lalanne JB, Wells CD, Li GW, Landick R, Hochschild A, Kondev J, Gelles J. Alternative transcription cycle for bacterial RNA polymerase. Nature Communications. 11: 448. PMID 31974358 DOI: 10.1038/S41467-019-14208-9  0.601
2020 Schiffman A, Ghosh I, Vera J, Landick R. Promoter Sequence Determinants of Transcription Initiation Rates in Zymomonas mobilis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05268  0.393
2019 Kang JY, Mishanina TV, Landick R, Darst SA. Mechanisms of Transcriptional Pausing in Bacteria. Journal of Molecular Biology. PMID 31310765 DOI: 10.1016/J.Jmb.2019.07.017  0.582
2019 Shen BA, Landick R. Transcription of Bacterial Chromatin. Journal of Molecular Biology. PMID 31153903 DOI: 10.1016/J.Jmb.2019.05.041  0.565
2019 Stumper SK, Ravi H, Friedman LJ, Mooney RA, Corrêa IR, Gershenson A, Landick R, Gelles J. Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. Elife. 8. PMID 30720429 DOI: 10.7554/Elife.40576  0.745
2019 Bellecourt MJ, Ray-Soni A, Harwig A, Mooney RA, Landick R. RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators. Journal of Molecular Biology. PMID 30630008 DOI: 10.1016/J.Jmb.2019.01.003  0.75
2019 Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. The elemental mechanism of transcriptional pausing. Elife. 8. PMID 30618376 DOI: 10.7554/Elife.40981  0.741
2019 Stumper SK, Ravi H, Friedman LJ, Mooney RA, Jnr IRC, Gershenson A, Landick R, Gelles J. Author response: Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription Elife. DOI: 10.7554/Elife.40576.Sa2  0.721
2018 Lawson MR, Ma W, Bellecourt MJ, Artsimovitch I, Martin A, Landick R, Schulten K, Berger JM. Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein. Molecular Cell. PMID 30122535 DOI: 10.1016/J.Molcel.2018.07.014  0.568
2018 Boudreau BA, Kotlajich MV, Landick R. In Vitro Transcription Assay to Quantify Effects of H-NS Filaments on RNA Chain Elongation by RNA Polymerase. Methods in Molecular Biology (Clifton, N.J.). 1837: 351-386. PMID 30109619 DOI: 10.1007/978-1-4939-8675-0_18  0.545
2018 Kang JY, Mooney RA, Nedialkov Y, Saba J, Mishanina TV, Artsimovitch I, Landick R, Darst SA. Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators. Cell. PMID 29887376 DOI: 10.1016/J.Cell.2018.05.017  0.739
2018 Boudreau BA, Hron DR, Qin L, van der Valk RA, Kotlajich MV, Dame RT, Landick R. StpA and Hha stimulate pausing by RNA polymerase by promoting DNA-DNA bridging of H-NS filaments. Nucleic Acids Research. PMID 29718386 DOI: 10.1093/Nar/Gky265  0.388
2018 Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H. Life times of metastable states guide regulatory signaling in transcriptional riboswitches. Nature Communications. 9: 944. PMID 29507289 DOI: 10.1038/S41467-018-03375-W  0.737
2018 Kang JY, Mishanina TV, Bellecourt MJ, Mooney RA, Darst SA, Landick R. RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing. Molecular Cell. 69: 802-815.e1. PMID 29499135 DOI: 10.1016/J.Molcel.2018.01.018  0.776
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. PMID 29480804 DOI: 10.7554/eLife.34823  0.666
2018 Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. Author response: The elemental mechanism of transcriptional pausing Elife. DOI: 10.7554/Elife.40981.025  0.605
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Author response: Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts Elife. DOI: 10.7554/Elife.34823.030  0.666
2018 Kang JY, Mooney RA, Artsimovitch I, Landick R, Darst SA. Molecular mechanism of transcription pause inhibition by elongation factor NusG and RfaH Cell. DOI: 10.2210/Pdb6C6T/Pdb  0.634
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. DOI: 10.2210/Pdb6C04/Pdb  0.677
2017 Ray-Soni A, Mooney RA, Landick R. Trigger loop dynamics can explain stimulation of intrinsic termination by bacterial RNA polymerase without terminator hairpin contact. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078293 DOI: 10.1073/Pnas.1706247114  0.741
2017 Harwig A, Landick R, Berkhout B. The Battle of RNA Synthesis: Virus versus Host. Viruses. 9. PMID 29065472 DOI: 10.3390/V9100309  0.599
2017 Mishanina TV, Palo MZ, Nayak D, Mooney RA, Landick R. Trigger loop of RNA polymerase is a positional, not acid-base, catalyst for both transcription and proofreading. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607053 DOI: 10.1073/Pnas.1702383114  0.748
2017 Feklistov A, Bae B, Hauver J, Lass-Napiorkowska A, Kalesse M, Glaus F, Altmann KH, Heyduk T, Landick R, Darst SA. RNA polymerase motions during promoter melting. Science (New York, N.Y.). 356: 863-866. PMID 28546214 DOI: 10.1126/Science.Aam7858  0.466
2017 Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm SK, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation. Elife. 6. PMID 28541183 DOI: 10.7554/Elife.21297  0.735
2017 Kohler R, Mooney RA, Mills DJ, Landick R, Cramer P. Architecture of a transcribing-translating expressome. Science (New York, N.Y.). 356: 194-197. PMID 28408604 DOI: 10.1126/Science.Aal3059  0.75
2017 Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Stumper SK, Mooney RA, Landick R, Gelles J. Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137878 DOI: 10.1073/Pnas.1616525114  0.711
2017 Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm S, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Author response: Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation Elife. DOI: 10.7554/Elife.21297.018  0.752
2016 Ray-Soni A, Bellecourt MJ, Landick R. Mechanisms of Bacterial Transcription Termination: All Good Things Must End. Annual Review of Biochemistry. PMID 27023849 DOI: 10.1146/Annurev-Biochem-060815-014844  0.627
2016 Zhang J, Landick R. A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure. Trends in Biochemical Sciences. PMID 26822487 DOI: 10.1016/J.Tibs.2015.12.009  0.731
2016 Ronayne EA, Wan YC, Boudreau BA, Landick R, Cox MM. P1 Ref Endonuclease: A Molecular Mechanism for Phage-Enhanced Antibiotic Lethality. Plos Genetics. 12: e1005797. PMID 26765929 DOI: 10.1371/Journal.Pgen.1005797  0.327
2016 Harden TT, Wells CD, Friedman LJ, Landick R, Hochschild A, Kondev J, Gelles J. Bacterial RNA polymerase can retain σ70 throughout transcription. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733675 DOI: 10.1073/Pnas.1513899113  0.567
2015 Bae B, Feklistov A, Lass-Napiorkowska A, Landick R, Darst SA. Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife. 4. PMID 26349032 DOI: 10.7554/Elife.08504  0.578
2015 Bae B, Nayak D, Ray A, Mustaev A, Landick R, Darst SA. CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195788 DOI: 10.1073/Pnas.1502368112  0.585
2015 Landick R, Wade JT, Grainger DC. H-NS and RNA polymerase: a love-hate relationship? Current Opinion in Microbiology. 24: 53-9. PMID 25638302 DOI: 10.1016/J.Mib.2015.01.009  0.469
2015 Kotlajich MV, Hron DR, Boudreau BA, Sun Z, Lyubchenko YL, Landick R. Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria. Elife. 4. PMID 25594903 DOI: 10.7554/Elife.04970  0.518
2015 Bae B, Feklistov A, Lass-Napiorkowska A, Landick R, Darst SA. Author response: Structure of a bacterial RNA polymerase holoenzyme open promoter complex Elife. DOI: 10.7554/Elife.08504.019  0.561
2015 Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Mooney RA, Landick R, Gelles J. Dynamics of GreB Interactions with RNA Polymerase: How a Regulatory Protein may Patrol the Genome for Transcription Complexes to Rescue Biophysical Journal. 108: 507a-508a. DOI: 10.1016/J.Bpj.2014.11.2778  0.729
2014 Windgassen TA, Mooney RA, Nayak D, Palangat M, Zhang J, Landick R. Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase. Nucleic Acids Research. 42: 12707-21. PMID 25336618 DOI: 10.1093/Nar/Gku997  0.769
2014 Keating DH, Zhang Y, Ong IM, McIlwain S, Morales EH, Grass JA, Tremaine M, Bothfeld W, Higbee A, Ulbrich A, Balloon AJ, Westphall MS, Aldrich J, Lipton MS, Kim J, ... ... Landick R, et al. Aromatic inhibitors derived from ammonia-pretreated lignocellulose hinder bacterial ethanologenesis by activating regulatory circuits controlling inhibitor efflux and detoxification. Frontiers in Microbiology. 5: 402. PMID 25177315 DOI: 10.3389/Fmicb.2014.00402  0.34
2014 Hein PP, Kolb KE, Windgassen T, Bellecourt MJ, Darst SA, Mooney RA, Landick R. RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement. Nature Structural & Molecular Biology. 21: 794-802. PMID 25108353 DOI: 10.1038/Nsmb.2867  0.847
2014 Landick R, Krek A, Glickman MS, Socci ND, Stallings CL. Genome-Wide Mapping of the Distribution of CarD, RNAP σ(A), and RNAP β on the Mycobacterium smegmatis Chromosome using Chromatin Immunoprecipitation Sequencing. Genomics Data. 2: 110-113. PMID 25089258 DOI: 10.1016/J.Gdata.2014.05.012  0.477
2014 Haft RJ, Keating DH, Schwaegler T, Schwalbach MS, Vinokur J, Tremaine M, Peters JM, Kotlajich MV, Pohlmann EL, Ong IM, Grass JA, Kiley PJ, Landick R. Correcting direct effects of ethanol on translation and transcription machinery confers ethanol tolerance in bacteria. Proceedings of the National Academy of Sciences of the United States of America. 111: E2576-85. PMID 24927582 DOI: 10.1073/Pnas.1401853111  0.594
2014 Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/Science.1251871  0.81
2014 Czyz A, Mooney RA, Iaconi A, Landick R. Mycobacterial RNA polymerase requires a U-tract at intrinsic terminators and is aided by NusG at suboptimal terminators. Mbio. 5: e00931. PMID 24713321 DOI: 10.1128/Mbio.00931-14  0.761
2014 Zhang Y, Mooney RA, Grass JA, Sivaramakrishnan P, Herman C, Landick R, Wang JD. DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest. Molecular Cell. 53: 766-78. PMID 24606919 DOI: 10.1016/J.Molcel.2014.02.005  0.776
2014 Kolb KE, Hein PP, Landick R. Antisense oligonucleotide-stimulated transcriptional pausing reveals RNA exit channel specificity of RNA polymerase and mechanistic contributions of NusA and RfaH. The Journal of Biological Chemistry. 289: 1151-63. PMID 24275665 DOI: 10.1074/Jbc.M113.521393  0.859
2014 Kotlajich MV, Hron DR, Boudreau BA, Sun Z, Lyubchenko YL, Landick R. Author response: Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria Elife. DOI: 10.7554/Elife.04970.027  0.517
2013 Park DM, Akhtar MS, Ansari AZ, Landick R, Kiley PJ. The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally Plos Genetics. 9. PMID 24146625 DOI: 10.1371/Journal.Pgen.1003839  0.366
2013 Chung D, Park D, Myers K, Grass J, Kiley P, Landick R, Keleş S. dPeak: high resolution identification of transcription factor binding sites from PET and SET ChIP-Seq data. Plos Computational Biology. 9: e1003246. PMID 24146601 DOI: 10.1371/Journal.Pcbi.1003246  0.342
2013 Srivastava DB, Leon K, Osmundson J, Garner AL, Weiss LA, Westblade LF, Glickman MS, Landick R, Darst SA, Stallings CL, Campbell EA. Structure and function of CarD, an essential mycobacterial transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 110: 12619-24. PMID 23858468 DOI: 10.1073/Pnas.1308270110  0.513
2013 Myers KS, Yan H, Ong IM, Chung D, Liang K, Tran F, KeleÅŸ S, Landick R, Kiley PJ. Genome-scale analysis of escherichia coli FNR reveals complex features of transcription factor binding. Plos Genetics. 9: e1003565. PMID 23818864 DOI: 10.1371/Journal.Pgen.1003565  0.364
2013 Mooney RA, Landick R. Building a better stop sign: understanding the signals that terminate transcription. Nature Methods. 10: 618-9. PMID 23807194 DOI: 10.1038/Nmeth.2527  0.639
2013 Nayak D, Voss M, Windgassen T, Mooney RA, Landick R. Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase. Molecular Cell. 50: 882-93. PMID 23769674 DOI: 10.1016/J.Molcel.2013.05.015  0.765
2013 Weixlbaumer A, Leon K, Landick R, Darst SA. Structural basis of transcriptional pausing in bacteria. Cell. 152: 431-41. PMID 23374340 DOI: 10.1016/J.Cell.2012.12.020  0.599
2012 Peters JM, Mooney RA, Grass JA, Jessen ED, Tran F, Landick R. Rho and NusG suppress pervasive antisense transcription in Escherichia coli. Genes & Development. 26: 2621-33. PMID 23207917 DOI: 10.1101/Gad.196741.112  0.779
2012 Koslover DJ, Fazal FM, Mooney RA, Landick R, Block SM. Binding and translocation of termination factor rho studied at the single-molecule level. Journal of Molecular Biology. 423: 664-76. PMID 22885804 DOI: 10.1016/J.Jmb.2012.07.027  0.725
2012 Burmann BM, Knauer SH, Sevostyanova A, Schweimer K, Mooney RA, Landick R, Artsimovitch I, Rösch P. An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor. Cell. 150: 291-303. PMID 22817892 DOI: 10.1016/J.Cell.2012.05.042  0.69
2012 Palangat M, Larson MH, Hu X, Gnatt A, Block SM, Landick R. Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II. Transcription. 3: 146-53. PMID 22771949 DOI: 10.4161/trns.20269  0.429
2012 Larson MH, Zhou J, Kaplan CD, Palangat M, Kornberg RD, Landick R, Block SM. Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 109: 6555-60. PMID 22493230 DOI: 10.1073/Pnas.1200939109  0.6
2012 Gourse RL, Landick R. CoSMoS unravels mysteries of transcription initiation. Cell. 148: 635-7. PMID 22341438 DOI: 10.1016/J.Cell.2012.01.042  0.463
2012 Zhou J, Larson MH, Kaplan C, Palangat M, Kornberg RD, Landick R, Block SM. RNA Polymerase II Translocation and Fidelity are Governed by Trigger Loop Dynamics: A Single-Molecule Study Biophysical Journal. 102: 285a. DOI: 10.1016/J.Bpj.2011.11.1576  0.595
2011 Zhou J, Ha KS, La Porta A, Landick R, Block SM. Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA. Molecular Cell. 44: 635-46. PMID 22099310 DOI: 10.1016/J.Molcel.2011.09.018  0.673
2011 Sevostyanova A, Belogurov GA, Mooney RA, Landick R, Artsimovitch I. The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG. Molecular Cell. 43: 253-62. PMID 21777814 DOI: 10.1016/J.Molcel.2011.05.026  0.751
2011 Hein PP, Palangat M, Landick R. RNA transcript 3'-proximal sequence affects translocation bias of RNA polymerase. Biochemistry. 50: 7002-14. PMID 21739957 DOI: 10.1021/Bi200437Q  0.861
2011 Palangat M, Grass JA, Langelier MF, Coulombe B, Landick R. The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation. Molecular and Cellular Biology. 31: 3312-25. PMID 21670157 DOI: 10.1128/Mcb.05318-11  0.546
2011 Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ. Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide. Methods in Enzymology. 498: 449-71. PMID 21601690 DOI: 10.1016/B978-0-12-385120-8.00020-6  0.692
2011 Peters JM, Vangeloff AD, Landick R. Bacterial transcription terminators: the RNA 3'-end chronicles. Journal of Molecular Biology. 412: 793-813. PMID 21439297 DOI: 10.1016/J.Jmb.2011.03.036  0.701
2011 Larson MH, Landick R, Block SM. Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes. Molecular Cell. 41: 249-62. PMID 21292158 DOI: 10.1016/J.Molcel.2011.01.008  0.451
2010 Hein PP, Landick R. The bridge helix coordinates movements of modules in RNA polymerase. Bmc Biology. 8: 141. PMID 21114873 DOI: 10.1186/1741-7007-8-141  0.84
2010 Conrad TM, Frazier M, Joyce AR, Cho BK, Knight EM, Lewis NE, Landick R, Palsson BØ. RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media. Proceedings of the National Academy of Sciences of the United States of America. 107: 20500-5. PMID 21057108 DOI: 10.1073/Pnas.0911253107  0.452
2010 Opalka N, Brown J, Lane WJ, Twist KA, Landick R, Asturias FJ, Darst SA. Complete structural model of Escherichia coli RNA polymerase from a hybrid approach. Plos Biology. 8. PMID 20856905 DOI: 10.1371/Journal.Pbio.1000483  0.45
2010 Cohen SE, Lewis CA, Mooney RA, Kohanski MA, Collins JJ, Landick R, Walker GC. Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 107: 15517-22. PMID 20696893 DOI: 10.1073/Pnas.1005203107  0.664
2010 Ha KS, Toulokhonov I, Vassylyev DG, Landick R. The NusA N-terminal domain is necessary and sufficient for enhancement of transcriptional pausing via interaction with the RNA exit channel of RNA polymerase. Journal of Molecular Biology. 401: 708-25. PMID 20600118 DOI: 10.1016/J.Jmb.2010.06.036  0.754
2010 Herbert KM, Zhou J, Mooney RA, Porta AL, Landick R, Block SM. E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. Journal of Molecular Biology. 399: 17-30. PMID 20381500 DOI: 10.1016/J.Jmb.2010.03.051  0.729
2010 Zhang J, Palangat M, Landick R. Role of the RNA polymerase trigger loop in catalysis and pausing. Nature Structural & Molecular Biology. 17: 99-104. PMID 19966797 DOI: 10.1038/Nsmb.1732  0.654
2009 Peters JM, Mooney RA, Kuan PF, Rowland JL, Keles S, Landick R. Rho directs widespread termination of intragenic and stable RNA transcription. Proceedings of the National Academy of Sciences of the United States of America. 106: 15406-11. PMID 19706412 DOI: 10.1073/Pnas.0903846106  0.823
2009 Mooney RA, Schweimer K, Rösch P, Gottesman M, Landick R. Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. Journal of Molecular Biology. 391: 341-58. PMID 19500594 DOI: 10.1016/J.Jmb.2009.05.078  0.745
2009 Landick R. Transcriptional pausing without backtracking. Proceedings of the National Academy of Sciences of the United States of America. 106: 8797-8. PMID 19470457 DOI: 10.1073/Pnas.0904373106  0.647
2009 Landick R. Functional divergence in the growing family of RNA polymerases. Structure (London, England : 1993). 17: 323-5. PMID 19278646 DOI: 10.1016/J.Str.2009.02.006  0.541
2009 Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R. Regulator trafficking on bacterial transcription units in vivo. Molecular Cell. 33: 97-108. PMID 19150431 DOI: 10.1016/J.Molcel.2008.12.021  0.771
2009 Belogurov GA, Mooney RA, Svetlov V, Landick R, Artsimovitch I. Functional specialization of transcription elongation factors. The Embo Journal. 28: 112-22. PMID 19096362 DOI: 10.1038/Emboj.2008.268  0.729
2009 Zhou J, Ha KS, La Porta A, Landick R, Block SM. Modulation Of Sequence-dependent Pausing Of RNA Polymerase By The Accessory Factor Nusa: A Single-molecule Study Biophysical Journal. 96: 57a. DOI: 10.1016/J.Bpj.2008.12.189  0.734
2008 Dufour YS, Landick R, Donohue TJ. Organization and evolution of the biological response to singlet oxygen stress. Journal of Molecular Biology. 383: 713-30. PMID 18723027 DOI: 10.1016/J.Jmb.2008.08.017  0.532
2008 Larson MH, Greenleaf WJ, Landick R, Block SM. Applied force reveals mechanistic and energetic details of transcription termination. Cell. 132: 971-82. PMID 18358810 DOI: 10.1016/J.Cell.2008.01.027  0.583
2008 Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. Journal of Proteome Research. 7: 1244-50. PMID 18271525 DOI: 10.1021/Pr070451J  0.71
2008 Vassylyev D, Vassylyeva M, Perederina A, Zhang J, Palangat M, Landick R, Tahirov T, Artsimovitch I. Structural basis of transcription: structures of the bacterial RNA polymerase elongation complexes Acta Crystallographica Section a Foundations of Crystallography. 64: C15-C16. DOI: 10.1107/S0108767308099558  0.653
2007 Toulokhonov I, Zhang J, Palangat M, Landick R. A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing. Molecular Cell. 27: 406-19. PMID 17679091 DOI: 10.1016/J.Molcel.2007.06.008  0.732
2007 Vassylyev DG, Vassylyeva MN, Zhang J, Palangat M, Artsimovitch I, Landick R. Structural basis for substrate loading in bacterial RNA polymerase. Nature. 448: 163-8. PMID 17581591 DOI: 10.1038/nature05931  0.604
2007 Kyzer S, Ha KS, Landick R, Palangat M. Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex. The Journal of Biological Chemistry. 282: 19020-8. PMID 17502377 DOI: 10.1074/Jbc.M701483200  0.768
2007 Davis CA, Bingman CA, Landick R, Record MT, Saecker RM. Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 104: 7833-8. PMID 17470797 DOI: 10.1073/Pnas.0609888104  0.447
2006 Landick R. A long time in the making--the Nobel Prize for RNA polymerase. Cell. 127: 1087-90. PMID 17174884 DOI: 10.1016/J.Cell.2006.11.036  0.586
2006 Landick R. The regulatory roles and mechanism of transcriptional pausing Biochemical Society Transactions. 34: 1062-1066. PMID 17073751 DOI: 10.1042/Bst0341062  0.548
2006 Toulokhonov I, Landick R. The role of the lid element in transcription by E. coli RNA polymerase. Journal of Molecular Biology. 361: 644-58. PMID 16876197 DOI: 10.1016/J.Jmb.2006.06.071  0.648
2006 Dalal RV, Larson MH, Neuman KC, Gelles J, Landick R, Block SM. Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. Molecular Cell. 23: 231-9. PMID 16857589 DOI: 10.1016/J.Molcel.2006.06.023  0.655
2006 Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM. Sequence-resolved detection of pausing by single RNA polymerase molecules. Cell. 125: 1083-94. PMID 16777599 DOI: 10.1016/J.Cell.2006.04.032  0.701
2006 Ederth J, Mooney RA, Isaksson LA, Landick R. Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket. Journal of Molecular Biology. 356: 1163-79. PMID 16405998 DOI: 10.1016/J.Jmb.2005.11.080  0.77
2005 Mooney RA, Darst SA, Landick R. Sigma and RNA polymerase: an on-again, off-again relationship? Molecular Cell. 20: 335-45. PMID 16285916 DOI: 10.1016/J.Molcel.2005.10.015  0.765
2005 Abbondanzieri EA, Greenleaf WJ, Shaevitz JW, Landick R, Block SM. Direct observation of base-pair stepping by RNA polymerase. Nature. 438: 460-5. PMID 16284617 DOI: 10.1038/Nature04268  0.593
2005 Landick R. NTP-entry routes in multi-subunit RNA polymerases. Trends in Biochemical Sciences. 30: 651-4. PMID 16243529 DOI: 10.1016/J.Tibs.2005.10.001  0.467
2005 Palangat M, Renner DB, Price DH, Landick R. A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS. Proceedings of the National Academy of Sciences of the United States of America. 102: 15036-41. PMID 16214896 DOI: 10.1073/Pnas.0409405102  0.577
2005 Kyzer S, Zhang J, Landick R. Inhibition of RNA polymerase by streptolydigin: no cycling allowed. Cell. 122: 494-6. PMID 16122417 DOI: 10.1016/J.Cell.2005.08.008  0.704
2005 Herring CD, Raffaelle M, Allen TE, Kanin EI, Landick R, Ansari AZ, Palsson BØ. Immobilization of Escherichia coli RNA polymerase and location of binding sites by use of chromatin immunoprecipitation and microarrays. Journal of Bacteriology. 187: 6166-74. PMID 16109958 DOI: 10.1128/Jb.187.17.6166-6174.2005  0.539
2005 Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, ... ... Landick RC, et al. An open letter to Elias Zerhouni. Science (New York, N.Y.). 307: 1409-10. PMID 15746409 DOI: 10.1126/Science.307.5714.1409C  0.427
2004 Geszvain K, Gruber TM, Mooney RA, Gross CA, Landick R. A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function. Journal of Molecular Biology. 343: 569-87. PMID 15465046 DOI: 10.1016/J.Jmb.2004.08.063  0.803
2004 Palangat M, Hittinger CT, Landick R. Downstream DNA selectively affects a paused conformation of human RNA polymerase II. Journal of Molecular Biology. 341: 429-42. PMID 15276834 DOI: 10.1016/J.Jmb.2004.06.009  0.509
2004 Landick R. Active-site dynamics in RNA polymerases. Cell. 116: 351-3. PMID 15016367 DOI: 10.1016/S0092-8674(04)00121-7  0.604
2004 Toli?-Nørrelykke SF, Engh AM, Landick R, Gelles J. Diversity in the rates of transcript elongation by single RNA polymerase molecules. The Journal of Biological Chemistry. 279: 3292-9. PMID 14604986 DOI: 10.1074/Jbc.M310290200  0.521
2003 Toulokhonov I, Landick R. The flap domain is required for pause RNA hairpin inhibition of catalysis by RNA polymerase and can modulate intrinsic termination. Molecular Cell. 12: 1125-36. PMID 14636572 DOI: 10.1016/S1097-2765(03)00439-8  0.615
2003 Shaevitz JW, Abbondanzieri EA, Landick R, Block SM. Backtracking by single RNA polymerase molecules observed at near-base-pair resolution. Nature. 426: 684-7. PMID 14634670 DOI: 10.1038/Nature02191  0.598
2003 Mooney RA, Landick R. Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations. Genes & Development. 17: 2839-51. PMID 14630944 DOI: 10.1101/Gad.1142203  0.737
2003 Neuman KC, Abbondanzieri EA, Landick R, Gelles J, Block SM. Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. Cell. 115: 437-47. PMID 14622598 DOI: 10.1016/S0092-8674(03)00845-6  0.577
2003 Artsimovitch I, Chu C, Lynch AS, Landick R. A new class of bacterial RNA polymerase inhibitor affects nucleotide addition. Science (New York, N.Y.). 302: 650-4. PMID 14576436 DOI: 10.1126/Science.1087526  0.572
2003 Wilson KA, Kalkum M, Ottesen J, Yuzenkova J, Chait BT, Landick R, Muir T, Severinov K, Darst SA. Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. Journal of the American Chemical Society. 125: 12475-83. PMID 14531691 DOI: 10.1021/Ja036756Q  0.422
2003 Santangelo TJ, Mooney RA, Landick R, Roberts JW. RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins. Genes & Development. 17: 1281-92. PMID 12756229 DOI: 10.1101/Gad.1082103  0.737
2003 Artsimovitch I, Svetlov V, Murakami KS, Landick R. Co-overexpression of Escherichia coli RNA polymerase subunits allows isolation and analysis of mutant enzymes lacking lineage-specific sequence insertions. The Journal of Biological Chemistry. 278: 12344-55. PMID 12511572 DOI: 10.1074/Jbc.M211214200  0.562
2002 Yuzenkova J, Delgado M, Nechaev S, Savalia D, Epshtein V, Artsimovitch I, Mooney RA, Landick R, Farias RN, Salomon R, Severinov K. Mutations of bacterial RNA polymerase leading to resistance to microcin j25. The Journal of Biological Chemistry. 277: 50867-75. PMID 12401787 DOI: 10.1074/Jbc.M209425200  0.635
2002 Ederth J, Artsimovitch I, Isaksson LA, Landick R. The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing. The Journal of Biological Chemistry. 277: 37456-63. PMID 12147705 DOI: 10.1074/Jbc.M207038200  0.612
2002 Artsimovitch I, Landick R. The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand. Cell. 109: 193-203. PMID 12007406 DOI: 10.1016/S0092-8674(02)00724-9  0.601
2001 Gruber TM, Markov D, Sharp MM, Young BA, Lu CZ, Zhong HJ, Artsimovitch I, Geszvain KM, Arthur TM, Burgess RR, Landick R, Severinov K, Gross CA. Binding of the initiation factor sigma(70) to core RNA polymerase is a multistep process. Molecular Cell. 8: 21-31. PMID 11511357 DOI: 10.1016/S1097-2765(01)00292-1  0.86
2001 Palangat M, Landick R. Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II Journal of Molecular Biology. 311: 265-282. PMID 11478860 DOI: 10.1006/Jmbi.2001.4842  0.621
2001 Landick R. RNA polymerase clamps down Cell. 105: 567-570. PMID 11389826 DOI: 10.1016/S0092-8674(01)00381-6  0.581
2001 Toulokhonov I, Artsimovitch I, Landick R. Allosteric control of RNA polymerase by a site that contacts nascent RNA hairpins Science. 292: 730-733. PMID 11326100 DOI: 10.1126/Science.1057738  0.645
2000 Artsimovitch I, Svetlov V, Anthony L, Burgess RR, Landick R. RNA polymerases from Bacillus subtilis and Escherichia coli differ in recognition of regulatory signals in vitro Journal of Bacteriology. 182: 6027-6035. PMID 11029421 DOI: 10.1128/Jb.182.21.6027-6035.2000  0.524
2000 Anthony LC, Artsimovitch I, Svetlov V, Landick R, Burgess RR. Rapid purification of His(6)-tagged Bacillus subtilis core RNA polymerase. Protein Expression and Purification. 19: 350-4. PMID 10910724 DOI: 10.1006/Prep.2000.1272  0.551
2000 Artsimovitch I, Landick R. Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals Proceedings of the National Academy of Sciences of the United States of America. 97: 7090-7095. PMID 10860976 DOI: 10.1073/Pnas.97.13.7090  0.614
2000 Davenport RJ, Wuite GJL, Landick R, Bustamante C. Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase Science. 287: 2497-2500. PMID 10741971 DOI: 10.1126/Science.287.5462.2497  0.611
2000 Opalka N, Mooney RA, Richter C, Severinov K, Landick R, Darst SA. Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 97: 617-22. PMID 10639128 DOI: 10.1073/Pnas.97.2.617  0.658
1999 Yin H, Artsimovitch I, Landick R, Gelles J. Nonequilibrium mechanism of transcription termination from observations of single RNA polymerase molecules. Proceedings of the National Academy of Sciences of the United States of America. 96: 13124-9. PMID 10557284 DOI: 10.1073/Pnas.96.23.13124  0.561
1999 Mooney RA, Landick R. RNA polymerase unveiled. Cell. 98: 687-90. PMID 10499791 DOI: 10.1016/S0092-8674(00)81483-X  0.712
1999 Keene RG, Mueller A, Landick R, London L. Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes Nucleic Acids Research. 27: 3173-3182. PMID 10454615 DOI: 10.1093/Nar/27.15.3173  0.492
1999 Pan T, Artsimovitch I, Fang XW, Landick R, Sosnick TR. Folding of a large ribozyme during transcription and the effect of the elongation factor NusA. Proceedings of the National Academy of Sciences of the United States of America. 96: 9545-50. PMID 10449729 DOI: 10.1073/Pnas.96.17.9545  0.638
1999 Landick R. Shifting RNA polymerase into overdrive Science. 284: 598-599. PMID 10328742 DOI: 10.1126/Science.284.5414.598  0.632
1998 Wang MD, Schnitzer MJ, Yin H, Landick R, Gelles J, Block SM. Force and velocity measured for single molecules of RNA polymerase. Science (New York, N.Y.). 282: 902-7. PMID 9794753 DOI: 10.1126/Science.282.5390.902  0.478
1998 Artsimovitch I, Landick R. Interaction of a nascent RNA structure with RNA polymerase is required for hairpin-dependent transcriptional pausing but not for transcript release Genes and Development. 12: 3110-3122. PMID 9765211 DOI: 10.1101/Gad.12.19.3110  0.644
1998 Palangat M, Meier TI, Keene RG, Landick R. Transcriptional pausing at +62 of the HIV-1 nascent RNA modulates formation of the TAR RNA structure. Molecular Cell. 1: 1033-42. PMID 9651586 DOI: 10.1016/S1097-2765(00)80103-3  0.569
1998 Mooney RA, Artsimovitch I, Landick R. Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation. Journal of Bacteriology. 180: 3265-75. PMID 9642176 DOI: 10.1128/Jb.180.13.3265-3275.1998  0.738
1998 Gelles J, Landick R. RNA polymerase as a molecular motor. Cell. 93: 13-6. PMID 9546386 DOI: 10.1016/S0092-8674(00)81140-X  0.421
1997 Severinov K, Mooney R, Darst SA, Landick R. Tethering of the large subunits of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 272: 24137-40. PMID 9305860 DOI: 10.1074/Jbc.272.39.24137  0.701
1997 Wang D, Severinov K, Landick R. Preferential interaction of the his pause RNA hairpin with RNA polymerase β subunit residues 904-950 correlates with strong transcriptional pausing Proceedings of the National Academy of Sciences of the United States of America. 94: 8433-8438. PMID 9237994 DOI: 10.1073/Pnas.94.16.8433  0.618
1997 Chan CL, Wang D, Landick R. Multiple interactions stabilize a single paused transcription intermediate in which hairpin to 3' end spacing distinguishes pause and termination pathways Journal of Molecular Biology. 268: 54-68. PMID 9149141 DOI: 10.1006/Jmbi.1997.0935  0.636
1997 Chan CL, Landick R. Effects of neutral salts on RNA chain elongation and pausing by Escherichia coli RNA polymerase Journal of Molecular Biology. 268: 37-53. PMID 9149140 DOI: 10.1006/Jmbi.1997.0934  0.618
1997 Wang MD, Yin H, Landick R, Gelles J, Block SM. Stretching DNA with optical tweezers. Biophysical Journal. 72: 1335-46. PMID 9138579 DOI: 10.1016/S0006-3495(97)78780-0  0.319
1997 Landick R. RNA polymerase slides home: Pause and termination site recognition Cell. 88: 741-744. PMID 9118216 DOI: 10.1016/S0092-8674(00)81919-4  0.45
1997 Wang D, Landick R. Nuclease cleavage of the upstream half of the nontemplate strand DNA in an Escherichia coli transcription elongation complex causes upstream translocation and transcriptional arrest Journal of Biological Chemistry. 272: 5989-5994. PMID 9038220 DOI: 10.1074/Jbc.272.9.5989  0.601
1996 Landick R, Wang D, Chan CL. Quantitative analysis of transcriptional pausing by Escherichia coli RNA polymerase: his leader pause site as paradigm Methods in Enzymology. 274: 334-353. PMID 8902817 DOI: 10.1016/S0076-6879(96)74029-6  0.645
1996 Tavormina PL, Landick R, Gross CA. Isolation, purification, and in vitro characterization of recessive- lethal-mutant RNA polymerases from Escherichia coli Journal of Bacteriology. 178: 5263-5271. PMID 8752347 DOI: 10.1128/Jb.178.17.5263-5271.1996  0.695
1996 Landick R, Roberts JW. The shrewd grasp of RNA polymerase. Science (New York, N.Y.). 273: 202-3. PMID 8668996 DOI: 10.1126/Science.273.5272.202  0.565
1996 Heisler LM, Feng G, Jin DJ, Gross CA, Landick R. Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex. The Journal of Biological Chemistry. 271: 14572-83. PMID 8662850 DOI: 10.1074/Jbc.271.24.14572  0.637
1995 Gelles J, Yin H, Finzi L, Wong OK, Landick R. Single-molecule kinetic studies on DNA transcription and transcriptional regulation. Biophysical Journal. 68: 73S. PMID 7787108  0.335
1995 Severinov K, Mustaev A, Severinova E, Bass I, Kashlev M, Landick R, Nikiforov V, Goldfarb A, Darst SA. Assembly of functional Escherichia coli RNA polymerase containing β subunit fragments Proceedings of the National Academy of Sciences of the United States of America. 92: 4591-4595. PMID 7753849 DOI: 10.1073/Pnas.92.10.4591  0.422
1995 Severinov K, Markov D, Severinova E, Nikiforov V, Landick R, Darst SA, Goldfarb A. Streptolydigin-resistant mutants in an evolutionarily conserved region of the beta' subunit of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 270: 23926-9. PMID 7592584 DOI: 10.1074/Jbc.270.41.23926  0.452
1995 Wang D, Meier TI, Chan CL, Feng G, Lee DN, Landick R. Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex. Cell. 81: 341-50. PMID 7537637 DOI: 10.1016/0092-8674(95)90387-9  0.634
1995 Yin H, Wang MD, Svoboda K, Landick R, Block SM, Gelles J. Transcription against an applied force. Science (New York, N.Y.). 270: 1653-7. PMID 7502073 DOI: 10.1126/Science.270.5242.1653  0.463
1994 Lee DN, Feng G, Landick R. GreA-induced transcript cleavage is accompanied by reverse translocation to a different transcription complex conformation. The Journal of Biological Chemistry. 269: 22295-303. PMID 8071356  0.528
1994 Feng GH, Lee DN, Wang D, Chan CL, Landick R. GreA-induced transcript cleavage in transcription complexes containing Escherichia coli RNA polymerase is controlled by multiple factors, including nascent transcript location and structure. The Journal of Biological Chemistry. 269: 22282-94. PMID 8071355  0.512
1994 Darst SA, Stebbins CE, Borukhov S, Orlova M, Feng G, Landick R, Goldfarb A. Crystallization of GreA, a transcript cleavage factor from Escherichia coli Journal of Molecular Biology. 242: 582-585. PMID 7932713 DOI: 10.1006/Jmbi.1994.1603  0.419
1994 Yin H, Landick R, Gelles J. Tethered particle motion method for studying transcript elongation by a single RNA polymerase molecule. Biophysical Journal. 67: 2468-78. PMID 7696485 DOI: 10.1016/S0006-3495(94)80735-0  0.393
1994 Weilbaecher R, Hebron C, Feng G, Landick R. Termination-altering amino acid substitutions in the β' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation Genes and Development. 8: 2913-2927. PMID 7527790 DOI: 10.1101/Gad.8.23.2913  0.546
1993 Chan CL, Landick R. Dissection of the his leader pause site by base substitution reveals a multipartite signal that includes a pause RNA hairpin Journal of Molecular Biology. 233: 25-42. PMID 8377190 DOI: 10.1006/Jmbi.1993.1482  0.646
1993 Heisler LM, Suzuki H, Landick R, Gross CA. Four contiguous amino acids define the target for streptolydigin resistance in the beta subunit of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 268: 25369-75. PMID 8244969  0.592
1992 Lee DN, Landick R. Structure of RNA and DNA chains in paused transcription complexes containing Escherichia coli RNA polymerase. Journal of Molecular Biology. 228: 759-77. PMID 1281887 DOI: 10.1016/0022-2836(92)90862-E  0.615
1991 Schafer DA, Gelles J, Sheetz MP, Landick R. Transcription by single molecules of RNA polymerase observed by light microscopy. Nature. 352: 444-8. PMID 1861724 DOI: 10.1038/352444A0  0.565
1991 London L, Keene RG, Landick R. Analysis of premature termination in c-myc during transcription by RNA polymerase II in a HeLa nuclear extract Molecular and Cellular Biology. 11: 4599-4615. PMID 1715021 DOI: 10.1128/Mcb.11.9.4599  0.512
1990 Landick R, Stewart J, Lee DN. Amino acid changes in conserved regions of the beta-subunit of Escherichia coli RNA polymerase alter transcription pausing and termination. Genes & Development. 4: 1623-36. PMID 2253882 DOI: 10.1101/Gad.4.9.1623  0.532
1990 Landick R, Yanofsky C, Choo K, Phung L. Replacement of the Escherichia coli trp operon attenuation control codons alters operon expression Journal of Molecular Biology. 216: 25-37. PMID 2231731 DOI: 10.1016/S0022-2836(05)80058-0  0.513
1990 Landick R, Colwell A, Stewart J. Insertional mutagenesis of a plasmid-borne Escherichia coli rpoB gene reveals alterations that inhibit β-subunit assembly into RNA polymerase Journal of Bacteriology. 172: 2844-2854. PMID 2160927 DOI: 10.1128/Jb.172.6.2844-2854.1990  0.506
1990 Lee DN, Phung L, Stewart J, Landick R. Transcription pausing by Escherichia coli RNA polymerase is modulated by downstream DNA sequences. The Journal of Biological Chemistry. 265: 15145-53. PMID 1697586  0.572
1989 Chan CL, Landick R. The Salmonella typhimurium his operon leader region contains an RNA hairpin-dependent transcription pause site. Mechanistic implications of the effect on pausing of altered RDNA hairpins Journal of Biological Chemistry. 264: 20796-20804. PMID 2479649  0.559
1987 Landick R, Yanofsky C. Isolation and structural analysis of the Escherichia coli trp leader paused transcription complex Journal of Molecular Biology. 196: 363-377. PMID 2443722 DOI: 10.1016/0022-2836(87)90697-8  0.594
1987 Landick R, Carey J, Yanofsky C. Detection of transcription-pausing in vivo in the trp operon leader region Proceedings of the National Academy of Sciences of the United States of America. 84: 1507-1511. PMID 2436219 DOI: 10.1073/Pnas.84.6.1507  0.637
1986 Nazos PM, Antonucci TK, Landick R, Oxender DL. Cloning and characterization of livH, the structural gene encoding a component of the leucine transport system in Escherichia coli Journal of Bacteriology. 166: 565-573. PMID 3009409 DOI: 10.1128/Jb.166.2.565-573.1986  0.314
1986 Stewart V, Landick R, Yanofsky C. Rho-dependent transcription termination in the tryptophanase operon leader region of Escherichia coli K-12 Journal of Bacteriology. 166: 217-223. PMID 2420781 DOI: 10.1128/Jb.166.1.217-223.1986  0.423
1985 Antonucci TK, Landick R, Oxender DL. The leucine binding proteins of Escherichia coli as models for studying the relationships between protein structure and function Journal of Cellular Biochemistry. 29: 209-216. PMID 4077929 DOI: 10.1002/Jcb.240290305  0.304
1985 Landick R, Carey J, Yanofsky C. Translation activates the paused transcription complex and restores transcription of the trp operon leader region Proceedings of the National Academy of Sciences of the United States of America. 82: 4663-4667. PMID 2991886 DOI: 10.1073/Pnas.82.14.4663  0.562
1984 Copeland BR, Landick R, Nazos PM, Oxender DL. Role of membrane potential in protein folding and domain formation during secretion in Escherichia coli Journal of Cellular Biochemistry. 24: 345-356. PMID 6381514 DOI: 10.1002/Jcb.240240405  0.317
1984 Landick R, Duncan JR, Copeland BR, Nazos PM, Oxender DL. Secretion and degradation of mutant leucine-specific binding protein molecules containing C-terminal deletions Journal of Cellular Biochemistry. 24: 331-344. PMID 6381513 DOI: 10.1002/Jcb.240240404  0.334
1984 Landick R, Yanofsky C. Stability of an RNA secondary structure affects in vitro transcription pausing in the trp Operon leader region Journal of Biological Chemistry. 259: 11550-11555. PMID 6206069  0.54
1984 Landick R, Vaughn V, Lau ET, VanBogelen RA, Erickson JW, Neidhardt FC. Nucleotide sequence of the heat shock regulatory gene of E. coli suggests its protein product may be a transcription factor. Cell. 38: 175-82. PMID 6088062 DOI: 10.1016/0092-8674(84)90538-5  0.425
1981 Landick R, Anderson JJ, Mayo MM, Gunsalus RP, Mavromara P, Daniels CJ, Oxender DL. Regulation of high-affinity leucine transport in Escherichia coli Journal of Supramolecular and Cellular Biochemistry. 14: 527-537. PMID 7017282 DOI: 10.1002/Jss.400140410  0.309
1980 Daniels CJ, Anderson JJ, Landick R, Oxender DL. The in vitro synthesis and processing of the branched-chain amino acid binding proteins Journal of Supramolecular and Cellular Biochemistry. 14: 305-311. PMID 7012452 DOI: 10.1002/Jss.400140305  0.342
1980 Oxender DL, Anderson JJ, Daniels CJ, Landick R, Gunsalus RP, Zurawski G, Yanofsky C. Amino-terminal sequence and processing of the precursor of the leucine-specific binding protein, and evidence for conformational differences between the precursor and the mature form Proceedings of the National Academy of Sciences of the United States of America. 77: 2005-2009. PMID 6990419 DOI: 10.1073/Pnas.77.4.2005  0.372
1980 Oxender DL, Anderson JJ, Daniels CJ, Landick R, Gunsalus RP, Zurawski G, Selker E, Yanofsky C. Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 77: 1412-6. PMID 6445555 DOI: 10.1073/Pnas.77.3.1412  0.356
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