Brett Finlay - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Cell Biology, Pathology

294 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Woodward SE, Neufeld LMP, Peña-Díaz J, Feng W, Serapio-Palacios A, Tarrant I, Deng W, Finlay BB. Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection. Plos Biology. 22: e3002761. PMID 39146372 DOI: 10.1371/journal.pbio.3002761  0.33
2024 Bosch TCG, Wigley M, Colomina B, Bohannan B, Meggers F, Amato KR, Azad MB, Blaser MJ, Brown K, Dominguez-Bello MG, Ehrlich SD, Elinav E, Finlay BB, Geddie K, Geva-Zatorsky N, et al. The potential importance of the built-environment microbiome and its impact on human health. Proceedings of the National Academy of Sciences of the United States of America. 121: e2313971121. PMID 38662573 DOI: 10.1073/pnas.2313971121  0.565
2023 Peña-Díaz J, Woodward SE, Creus-Cuadros A, Serapio-Palacios A, Ortiz-Jiménez S, Deng W, Finlay BB. Quorum sensing modulates bacterial virulence and colonization dynamics of the gastrointestinal pathogen . Gut Microbes. 15: 2267189. PMID 37842938 DOI: 10.1080/19490976.2023.2267189  0.363
2022 Serapio-Palacios A, Woodward SE, Vogt SL, Deng W, Creus-Cuadros A, Huus KE, Cirstea M, Gerrie M, Barcik W, Yu H, Finlay BB. Type VI secretion systems of pathogenic and commensal bacteria mediate niche occupancy in the gut. Cell Reports. 39: 110731. PMID 35476983 DOI: 10.1016/j.celrep.2022.110731  0.378
2021 Knuff-Janzen K, Serapio-Palacios A, McCoy J, Krekhno Z, Moon KM, Deng W, Foster LJ, Finlay BB. Quantitative proteomic screen identifies annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2. Scientific Reports. 11: 23630. PMID 34880286 DOI: 10.1038/s41598-021-02795-x  0.447
2021 Finlay BB, Amato KR, Azad M, Blaser MJ, Bosch TCG, Chu H, Dominguez-Bello MG, Ehrlich SD, Elinav E, Geva-Zatorsky N, Gros P, Guillemin K, Keck F, Korem T, McFall-Ngai MJ, et al. The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33472859 DOI: 10.1073/pnas.2010217118  0.541
2021 Lyons BJE, Atkinson CE, Deng W, Serapio-Palacios A, Finlay BB, Strynadka NCJ. Cryo-EM structure of the EspA filament from enteropathogenic Escherichia coli: revealing the mechanism of effector translocation in the T3SS. Structure (London, England : 1993). PMID 33453150 DOI: 10.1016/j.str.2020.12.009  0.316
2021 Sekirov I, Gill N, Jogova M, Tam N, Robertson M, de Llanos R, Li Y, Finlay BB. Salmonella SPI-1-mediated neutrophil recruitment during enteric colitis is associated with reduction and alteration in intestinal microbiota. Gut Microbes. 1: 30-41. PMID 21327114 DOI: 10.4161/gmic.1.1.10950  0.319
2020 Knuff-Janzen K, Tupin A, Yurist-Doutsch S, Rowland JL, Finlay BB. Multiple Salmonella-pathogenicity island 2 effectors are required to facilitate bacterial establishment of its intracellular niche and virulence. Plos One. 15: e0235020. PMID 32584855 DOI: 10.1371/Journal.Pone.0235020  0.479
2020 Huus KE, Bauer KC, Brown EM, Bozorgmehr T, Woodward SE, Serapio-Palacios A, Boutin RCT, Petersen C, Finlay BB. Commensal Bacteria Modulate Immunoglobulin A Binding in Response to Host Nutrition. Cell Host & Microbe. PMID 32289261 DOI: 10.1016/j.chom.2020.03.012  0.306
2019 Woodward SE, Krekhno Z, Finlay BB. Here, there, and everywhere: How pathogenic E. coli sense and respond to gastrointestinal biogeography. Cellular Microbiology. e13107. PMID 31454133 DOI: 10.1111/cmi.13107  0.434
2019 Brown EM, Ke X, Hitchcock D, Jeanfavre S, Avila-Pacheco J, Nakata T, Arthur TD, Fornelos N, Heim C, Franzosa EA, Watson N, Huttenhower C, Haiser HJ, Dillow G, Graham DB, ... Finlay BB, et al. Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis. Cell Host & Microbe. 25: 668-680.e7. PMID 31071294 DOI: 10.1016/J.Chom.2019.04.002  0.325
2018 Vogt SL, Scholz R, Peng Y, Guest RL, Scott NE, Woodward SE, Foster LJ, Raivio TL, Finlay BB. Characterization of the Citrobacter rodentium Cpx regulon and its role in host infection. Molecular Microbiology. PMID 30536519 DOI: 10.1111/Mmi.14182  0.379
2018 Tseytin I, Madar A, Mitrovic B, Deng W, Finlay BB, Sal-Man N. The Third Transmembrane Domain of EscR Is Critical for Function of the Enteropathogenic Type III Secretion System. Msphere. 3. PMID 30045964 DOI: 10.1128/mSphere.00162-18  0.366
2018 Ingram JP, Tursi S, Zhang T, Guo W, Yin C, A Wynosky-Dolfi M, van der Heijden J, Cai KQ, Yamamoto M, Finlay BB, Brodsky IE, Grivennikov SI, Tükel Ç, Balachandran S. A Nonpyroptotic IFN-γ-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Clearance In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 29654208 DOI: 10.4049/jimmunol.1701386  0.639
2017 Partida-Rodríguez O, Serrano-Vázquez A, Nieves-Ramírez ME, Moran P, Rojas L, Portillo T, González E, Hernández E, Finlay BB, Ximenez C. Human Intestinal Microbiota: Interaction Between Parasites and the Host Immune Response. Archives of Medical Research. PMID 29290328 DOI: 10.1016/j.arcmed.2017.11.015  0.33
2017 Knuff K, Finlay BB. What the SIF Is Happening-The Role of Intracellular Salmonella-Induced Filaments. Frontiers in Cellular and Infection Microbiology. 7: 335. PMID 28791257 DOI: 10.3389/fcimb.2017.00335  0.481
2017 Peixoto RJM, Alves ES, Wang M, Ferreira RBR, Granato A, Han J, Gill H, Jacobson K, Lobo LA, Domingues RMCP, Borchers CH, Davies JE, Finlay BB, Antunes LCM. Repression of Salmonella host cell invasion by aromatic small molecules from the human fecal metabolome. Applied and Environmental Microbiology. PMID 28754707 DOI: 10.1128/Aem.01148-17  0.312
2017 Ju T, Shoblak Y, Gao Y, Yang K, Fouhse J, Finlay BB, So YW, Stothard P, Willing BP. Initial gut microbial composition as a key factor driving host response to antibiotic treatment, as exemplified by the presence or absence of commensal Escherichia coli. Applied and Environmental Microbiology. PMID 28667114 DOI: 10.1128/Aem.01107-17  0.34
2017 Vogt SL, Finlay BB. Gut microbiota-mediated protection against diarrheal infections. Journal of Travel Medicine. 24: S39-S43. PMID 28520994 DOI: 10.1093/Jtm/Taw086  0.348
2017 Deng W, Marshall NC, Rowland JL, McCoy JM, Worrall LJ, Santos AS, Strynadka NC, Finlay BB. Assembly, structure, function and regulation of type III secretion systems. Nature Reviews. Microbiology. PMID 28392566 DOI: 10.1038/Nrmicro.2017.20  0.372
2017 Reynolds LA, Redpath SA, Yurist-Doutsch S, Gill N, Brown EM, van der Heijden J, Brosschot TP, Han J, Marshall NC, Woodward SE, Valdez Y, Borchers CH, Perona-Wright G, Finlay BB. Enteric helminths promote Salmonella co-infection by altering the intestinal metabolome. The Journal of Infectious Diseases. PMID 28368463 DOI: 10.1093/infdis/jix141  0.371
2017 Marshall NC, Finlay BB, Overall CM. Sharpening host defenses during infection: Proteases cut to the chase. Molecular & Cellular Proteomics : McP. PMID 28179412 DOI: 10.1074/Mcp.O116.066456  0.365
2017 Shaulov L, Gershberg J, Deng W, Finlay BB, Sal-Man N. The Ruler Protein EscP of the Enteropathogenic Escherichia coli Type III Secretion System Is Involved in Calcium Sensing and Secretion Hierarchy Regulation by Interacting with the Gatekeeper Protein SepL. Mbio. 8. PMID 28049143 DOI: 10.1128/mBio.01733-16  0.354
2016 Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC. Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature. PMID 27974800 DOI: 10.1038/Nature20576  0.324
2016 Tourret J, Willing BP, Dion S, MacPherson J, Denamur E, Finlay BB. Immunosuppressive treatment alters secretion of ileal antimicrobial peptides and gut microbiota, and favors subsequent colonization by uropathogenic Escherichia coli. Transplantation. PMID 27681266 DOI: 10.1016/J.Ekir.2016.09.039  0.349
2016 Yurist-Doutsch S, Arrieta MC, Tupin A, Valdez Y, Antunes LC, Yen R, Finlay BB. Nutrient Deprivation Affects Salmonella Invasion and Its Interaction with the Gastrointestinal Microbiota. Plos One. 11: e0159676. PMID 27437699 DOI: 10.1371/journal.pone.0159676  0.323
2016 Law RJ, Law HT, Scurll JM, Scholz R, Santos AS, Shames SR, Deng W, Croxen MA, Li Y, de Hoog CL, van der Heijden J, Foster LJ, Guttman JA, Finlay BB. Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors. Journal of Proteome Research. PMID 27018634 DOI: 10.1021/Acs.Jproteome.6B00074  0.419
2016 North JR, Takenaka S, Rozek A, Kielczewska A, Opal S, Morici LA, Finlay BB, Schaber CJ, Straube R, Donini O. A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy. Journal of Biotechnology. PMID 27015977 DOI: 10.1016/J.Jbiotec.2016.03.032  0.343
2015 Reynolds LA, Finlay BB, Maizels RM. Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity. Journal of Immunology (Baltimore, Md. : 1950). 195: 4059-66. PMID 26477048 DOI: 10.4049/jimmunol.1501432  0.349
2015 Connolly JP, Finlay BB, Roe AJ. From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli. Frontiers in Microbiology. 6: 568. PMID 26097473 DOI: 10.3389/fmicb.2015.00568  0.371
2015 Vogt SL, Peña-Díaz J, Finlay BB. Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens. Anaerobe. 34: 106-115. PMID 25958185 DOI: 10.1016/J.Anaerobe.2015.05.002  0.368
2015 Scholz R, Imami K, Scott NE, Trimble WS, Foster LJ, Finlay BB. Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis. Molecular & Cellular Proteomics : McP. PMID 25944883 DOI: 10.1074/Mcp.M114.046847  0.411
2015 Bhullar K, Zarepour M, Yu H, Yang H, Croxen M, Stahl M, Finlay BB, Turvey SE, Vallance BA. The serine protease autotransporter Pic modulates Citrobacter rodentium pathogenesis and its innate recognition by the host. Infection and Immunity. PMID 25895966 DOI: 10.1128/IAI.00025-15  0.338
2015 Burkinshaw BJ, Deng W, Lameignère E, Wasney GA, Zhu H, Worrall LJ, Finlay BB, Strynadka NC. Structural analysis of a specialized type III secretion system peptidoglycan-cleaving enzyme. The Journal of Biological Chemistry. 290: 10406-17. PMID 25678709 DOI: 10.1074/jbc.M115.639013  0.3
2015 Caballero-Flores GG, Croxen MA, Martínez-Santos VI, Finlay BB, Puente JL. Identification and regulation of a novel Citrobacter rodentium gut colonization fimbria (Gcf). Journal of Bacteriology. 197: 1478-91. PMID 25666139 DOI: 10.1128/JB.02486-14  0.356
2015 Deng W, Yu HB, Li Y, Finlay BB. SepD/SepL-dependent secretion signals of the type III secretion system translocator proteins in enteropathogenic Escherichia coli. Journal of Bacteriology. 197: 1263-75. PMID 25645555 DOI: 10.1128/JB.02401-14  0.313
2015 Santos AS, Finlay BB. Bringing down the host: enteropathogenic and enterohaemorrhagic Escherichia coli effector-mediated subversion of host innate immune pathways. Cellular Microbiology. 17: 318-32. PMID 25588886 DOI: 10.1111/cmi.12412  0.451
2015 van der Heijden J, Bosman ES, Reynolds LA, Finlay BB. Direct measurement of oxidative and nitrosative stress dynamics in Salmonella inside macrophages. Proceedings of the National Academy of Sciences of the United States of America. 112: 560-5. PMID 25548165 DOI: 10.1073/pnas.1414569112  0.325
2014 Roberts ME, Bishop JL, Fan X, Beer JL, Kum WW, Krebs DL, Huang M, Gill N, Priatel JJ, Finlay BB, Harder KW. Lyn deficiency leads to increased microbiota-dependent intestinal inflammation and susceptibility to enteric pathogens. Journal of Immunology (Baltimore, Md. : 1950). 193: 5249-63. PMID 25339668 DOI: 10.4049/jimmunol.1302832  0.318
2014 Yurist-Doutsch S, Arrieta MC, Vogt SL, Finlay BB. Gastrointestinal microbiota-mediated control of enteric pathogens. Annual Review of Genetics. 48: 361-82. PMID 25251855 DOI: 10.1146/Annurev-Genet-120213-092421  0.303
2014 Reynolds LA, Smith KA, Filbey KJ, Harcus Y, Hewitson JP, Redpath SA, Valdez Y, Yebra MJ, Finlay BB, Maizels RM. Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites. Gut Microbes. 5: 522-32. PMID 25144609 DOI: 10.4161/gmic.32155  0.366
2014 Collins JW, Keeney KM, Crepin VF, Rathinam VA, Fitzgerald KA, Finlay BB, Frankel G. Citrobacter rodentium: infection, inflammation and the microbiota. Nature Reviews. Microbiology. 12: 612-23. PMID 25088150 DOI: 10.1038/Nrmicro3315  0.344
2014 Antunes LC, McDonald JA, Schroeter K, Carlucci C, Ferreira RB, Wang M, Yurist-Doutsch S, Hira G, Jacobson K, Davies J, Allen-Vercoe E, Finlay BB. Antivirulence activity of the human gut metabolome. Mbio. 5: e01183-14. PMID 25073640 DOI: 10.1128/Mbio.01183-14  0.321
2014 Yu HB, Croxen MA, Marchiando AM, Ferreira RB, Cadwell K, Foster LJ, Finlay BB. Autophagy facilitates Salmonella replication in HeLa cells. Mbio. 5: e00865-14. PMID 24618251 DOI: 10.1128/Mbio.00865-14  0.324
2014 Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell. 156: 1045-59. PMID 24581500 DOI: 10.1016/J.Cell.2014.01.026  0.381
2014 Mattos KA, Oliveira VC, Berrêdo-Pinho M, Amaral JJ, Antunes LC, Melo RC, Acosta CC, Moura DF, Olmo R, Han J, Rosa PS, Almeida PE, Finlay BB, Borchers CH, Sarno EN, et al. Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment. Cellular Microbiology. 16: 797-815. PMID 24552180 DOI: 10.1111/cmi.12279  0.599
2014 Marshall NC, Finlay BB. Targeting the type III secretion system to treat bacterial infections. Expert Opinion On Therapeutic Targets. 18: 137-52. PMID 24295327 DOI: 10.1517/14728222.2014.855199  0.345
2014 Stiemsma LT, Turvey SE, Finlay BB. An antibiotic-altered microbiota provides fuel for the enteric foe. Cell Research. 24: 5-6. PMID 24165893 DOI: 10.1038/cr.2013.142  0.328
2013 Amaral JJ, Antunes LC, de Macedo CS, Mattos KA, Han J, Pan J, Candéa AL, Henriques Md, Ribeiro-Alves M, Borchers CH, Sarno EN, Bozza PT, Finlay BB, Pessolani MC. Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease. Plos Neglected Tropical Diseases. 7: e2381. PMID 23967366 DOI: 10.1371/journal.pntd.0002381  0.529
2013 Marchiando AM, Ramanan D, Ding Y, Gomez LE, Hubbard-Lucey VM, Maurer K, Wang C, Ziel JW, van Rooijen N, Nuñez G, Finlay BB, Mysorekar IU, Cadwell K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. Cell Host & Microbe. 14: 216-24. PMID 23954160 DOI: 10.1016/J.Chom.2013.07.013  0.321
2013 Bhavsar AP, Brown NF, Stoepel J, Wiermer M, Martin DD, Hsu KJ, Imami K, Ross CJ, Hayden MR, Foster LJ, Li X, Hieter P, Finlay BB. The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity. Plos Pathogens. 9: e1003518. PMID 23935490 DOI: 10.1371/Journal.Ppat.1003518  0.379
2013 Sal-Man N, Setiaputra D, Scholz R, Deng W, Yu AC, Strynadka NC, Finlay BB. EscE and EscG are cochaperones for the type III needle protein EscF of enteropathogenic Escherichia coli. Journal of Bacteriology. 195: 2481-9. PMID 23524615 DOI: 10.1128/JB.00118-13  0.311
2013 Imami K, Bhavsar AP, Yu H, Brown NF, Rogers LD, Finlay BB, Foster LJ. Global impact of Salmonella pathogenicity island 2-secreted effectors on the host phosphoproteome. Molecular & Cellular Proteomics : McP. 12: 1632-43. PMID 23459991 DOI: 10.1074/mcp.M112.026161  0.44
2013 Law RJ, Gur-Arie L, Rosenshine I, Finlay BB. In vitro and in vivo model systems for studying enteropathogenic Escherichia coli infections. Cold Spring Harbor Perspectives in Medicine. 3: a009977. PMID 23457294 DOI: 10.1101/cshperspect.a009977  0.418
2013 Olsen RL, Echtenkamp F, Cheranova D, Deng W, Finlay BB, Hardwidge PR. The enterohemorrhagic Escherichia coli effector protein NleF binds mammalian Tmp21. Veterinary Microbiology. 164: 164-70. PMID 23434013 DOI: 10.1016/J.Vetmic.2013.01.028  0.405
2013 Keeney KM, Finlay BB. Microbiology: EHEC downregulates virulence in response to intestinal fucose. Current Biology : Cb. 23: R108-10. PMID 23391383 DOI: 10.1016/J.Cub.2012.12.027  0.324
2013 Kindrachuk J, Jenssen H, Elliott M, Nijnik A, Magrangeas-Janot L, Pasupuleti M, Thorson L, Ma S, Easton DM, Bains M, Finlay B, Breukink EJ, Georg-Sahl H, Hancock RE. Manipulation of innate immunity by a bacterial secreted peptide: lantibiotic nisin Z is selectively immunomodulatory. Innate Immunity. 19: 315-27. PMID 23109507 DOI: 10.1177/1753425912461456  0.449
2012 Gill N, Ferreira RB, Antunes LC, Willing BP, Sekirov I, Al-Zahrani F, Hartmann M, Finlay BB. Neutrophil elastase alters the murine gut microbiota resulting in enhanced Salmonella colonization. Plos One. 7: e49646. PMID 23155475 DOI: 10.1371/journal.pone.0049646  0.309
2012 Prehna G, Li Y, Stoynov N, Okon M, Vuckovic M, McIntosh LP, Foster LJ, Finlay BB, Strynadka NC. The zinc regulated antivirulence pathway of Salmonella is a multiprotein immunoglobulin adhesion system. The Journal of Biological Chemistry. 287: 32324-37. PMID 22810234 DOI: 10.1074/Jbc.M112.357210  0.355
2012 van der Heijden J, Finlay BB. Type III effector-mediated processes in Salmonella infection. Future Microbiology. 7: 685-703. PMID 22702524 DOI: 10.2217/fmb.12.49  0.345
2012 Cortés-Vieyra R, Bravo-Patiño A, Valdez-Alarcón JJ, Juárez MC, Finlay BB, Baizabal-Aguirre VM. Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens. Journal of Inflammation (London, England). 9: 23. PMID 22691598 DOI: 10.1186/1476-9255-9-23  0.343
2012 Deng W, Yu HB, de Hoog CL, Stoynov N, Li Y, Foster LJ, Finlay BB. Quantitative proteomic analysis of type III secretome of enteropathogenic Escherichia coli reveals an expanded effector repertoire for attaching/effacing bacterial pathogens. Molecular & Cellular Proteomics : McP. 11: 692-709. PMID 22661456 DOI: 10.1074/mcp.M111.013672  0.385
2012 McCormick B, Finlay B. Special edition of gut microbes. Gut Microbes. 3: 61. PMID 22555468 DOI: 10.4161/Gmic.19936  0.435
2012 Sal-Man N, Biemans-Oldehinkel E, Sharon D, Croxen MA, Scholz R, Foster LJ, Finlay BB. EscA is a crucial component of the type III secretion system of enteropathogenic Escherichia coli. Journal of Bacteriology. 194: 2819-28. PMID 22447907 DOI: 10.1128/JB.00103-12  0.342
2012 Shames SR, Finlay BB. Bacterial effector interplay: a new way to view effector function. Trends in Microbiology. 20: 214-9. PMID 22425230 DOI: 10.1016/j.tim.2012.02.007  0.46
2012 Antunes LC, Wang M, Andersen SK, Ferreira RB, Kappelhoff R, Han J, Borchers CH, Finlay BB. Repression of Salmonella enterica phoP expression by small molecules from physiological bile. Journal of Bacteriology. 194: 2286-96. PMID 22366421 DOI: 10.1128/JB.00104-12  0.367
2012 Sal-Man N, Deng W, Finlay BB. EscI: a crucial component of the type III secretion system forms the inner rod structure in enteropathogenic Escherichia coli. The Biochemical Journal. 442: 119-25. PMID 22087554 DOI: 10.1042/BJ20111620  0.381
2012 Auweter SD, Yu HB, Arena ET, Guttman JA, Finlay BB. Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus. Microbes and Infection / Institut Pasteur. 14: 148-54. PMID 21988961 DOI: 10.1016/J.Micinf.2011.09.003  0.37
2011 Willing BP, Vacharaksa A, Croxen M, Thanachayanont T, Finlay BB. Altering host resistance to infections through microbial transplantation. Plos One. 6: e26988. PMID 22046427 DOI: 10.1371/journal.pone.0026988  0.331
2011 Brown NF, Finlay BB. Potential origins and horizontal transfer of type III secretion systems and effectors. Mobile Genetic Elements. 1: 118-121. PMID 22016859 DOI: 10.4161/mge.1.2.16733  0.374
2011 Shames SR, Croxen MA, Deng W, Finlay BB. The type III system-secreted effector EspZ localizes to host mitochondria and interacts with the translocase of inner mitochondrial membrane 17b. Infection and Immunity. 79: 4784-90. PMID 21947777 DOI: 10.1128/IAI.05761-11  0.434
2011 Arena ET, Auweter SD, Antunes LC, Vogl AW, Han J, Guttman JA, Croxen MA, Menendez A, Covey SD, Borchers CH, Finlay BB. The deubiquitinase activity of the Salmonella pathogenicity island 2 effector, SseL, prevents accumulation of cellular lipid droplets. Infection and Immunity. 79: 4392-400. PMID 21875964 DOI: 10.1128/Iai.05478-11  0.418
2011 Shames SR, Bhavsar AP, Croxen MA, Law RJ, Mak SH, Deng W, Li Y, Bidshari R, de Hoog CL, Foster LJ, Finlay BB. The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300. Cellular Microbiology. 13: 1542-57. PMID 21812888 DOI: 10.1111/j.1462-5822.2011.01640.x  0.344
2011 Antunes LC, Andersen SK, Menendez A, Arena ET, Han J, Ferreira RB, Borchers CH, Finlay BB. Metabolomics reveals phospholipids as important nutrient sources during Salmonella growth in bile in vitro and in vivo. Journal of Bacteriology. 193: 4719-25. PMID 21764918 DOI: 10.1128/JB.05132-11  0.35
2011 Sham HP, Shames SR, Croxen MA, Ma C, Chan JM, Khan MA, Wickham ME, Deng W, Finlay BB, Vallance BA. Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation. Infection and Immunity. 79: 3552-62. PMID 21746856 DOI: 10.1128/IAI.05033-11  0.366
2011 Antunes LC, Finlay BB. A comparative analysis of the effect of antibiotic treatment and enteric infection on intestinal homeostasis. Gut Microbes. 2: 105-8. PMID 21637027  0.589
2011 Ferreira RB, Gill N, Willing BP, Antunes LC, Russell SL, Croxen MA, Finlay BB. The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. Plos One. 6: e20338. PMID 21633507 DOI: 10.1371/journal.pone.0020338  0.313
2011 Gal-Mor O, Elhadad D, Deng W, Rahav G, Finlay BB. The Salmonella enterica PhoP directly activates the horizontally acquired SPI-2 gene sseL and is functionally different from a S. bongori ortholog. Plos One. 6: e20024. PMID 21625519 DOI: 10.1371/journal.pone.0020024  0.309
2011 Auweter SD, Bhavsar AP, de Hoog CL, Li Y, Chan YA, van der Heijden J, Lowden MJ, Coombes BK, Rogers LD, Stoynov N, Foster LJ, Finlay BB. Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners. The Journal of Biological Chemistry. 286: 24023-35. PMID 21566117 DOI: 10.1074/Jbc.M111.224600  0.469
2011 Buckner MM, Croxen MA, Arena ET, Finlay BB. A comprehensive study of the contribution of Salmonella enterica serovar Typhimurium SPI2 effectors to bacterial colonization, survival, and replication in typhoid fever, macrophage, and epithelial cell infection models. Virulence. 2: 208-16. PMID 21540636 DOI: 10.4161/viru.2.3.15894  0.428
2011 Willing BP, Antunes LC, Keeney KM, Ferreira RB, Finlay BB. Harvesting the biological potential of the human gut microbiome. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 414-8. PMID 21500237 DOI: 10.1002/Bies.201100030  0.328
2011 Brown NF, Coombes BK, Bishop JL, Wickham ME, Lowden MJ, Gal-Mor O, Goode DL, Boyle EC, Sanderson KL, Finlay BB. Salmonella phage ST64B encodes a member of the SseK/NleB effector family. Plos One. 6: e17824. PMID 21445262 DOI: 10.1371/Journal.Pone.0017824  0.396
2011 Willing BP, Russell SL, Finlay BB. Shifting the balance: antibiotic effects on host-microbiota mutualism. Nature Reviews. Microbiology. 9: 233-43. PMID 21358670 DOI: 10.1038/nrmicro2536  0.344
2011 Antunes LC, Arena ET, Menendez A, Han J, Ferreira RB, Buckner MM, Lolic P, Madilao LL, Bohlmann J, Borchers CH, Finlay BB. Impact of salmonella infection on host hormone metabolism revealed by metabolomics. Infection and Immunity. 79: 1759-69. PMID 21321075 DOI: 10.1128/Iai.01373-10  0.36
2010 Willing BP, Gill N, Finlay BB. The role of the immune system in regulating the microbiota. Gut Microbes. 1: 213-223. PMID 21327028 DOI: 10.4161/gmic.1.4.12520  0.346
2010 Shames SR, Finlay BB. Breaking the stereotype: virulence factor-mediated protection of host cells in bacterial pathogenesis. Plos Pathogens. 6: e1001057. PMID 20862318 DOI: 10.1371/journal.ppat.1001057  0.416
2010 Xie HX, Yu HB, Zheng J, Nie P, Foster LJ, Mok YK, Finlay BB, Leung KY. EseG, an effector of the type III secretion system of Edwardsiella tarda, triggers microtubule destabilization. Infection and Immunity. 78: 5011-21. PMID 20855515 DOI: 10.1128/IAI.00152-10  0.404
2010 Xicohtencatl-Cortes J, Saldaña Z, Deng W, Castañeda E, Freer E, Tarr PI, Finlay BB, Puente JL, Girón JA. Bacterial macroscopic rope-like fibers with cytopathic and adhesive properties. The Journal of Biological Chemistry. 285: 32336-42. PMID 20688909 DOI: 10.1074/jbc.M110.162248  0.328
2010 Antunes LC, Buckner MM, Auweter SD, Ferreira RB, Lolić P, Finlay BB. Inhibition of Salmonella host cell invasion by dimethyl sulfide. Applied and Environmental Microbiology. 76: 5300-4. PMID 20562287 DOI: 10.1128/AEM.00851-10  0.306
2010 Bakowski MA, Braun V, Lam GY, Yeung T, Heo WD, Meyer T, Finlay BB, Grinstein S, Brumell JH. The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host & Microbe. 7: 453-62. PMID 20542249 DOI: 10.1016/J.Chom.2010.05.011  0.756
2010 Guttman JA, Lin AE, Veiga E, Cossart P, Finlay BB. Role for CD2AP and other endocytosis-associated proteins in enteropathogenic Escherichia coli pedestal formation. Infection and Immunity. 78: 3316-22. PMID 20515931 DOI: 10.1128/IAI.00161-10  0.342
2010 Antunes LC, Ferreira RB, Buckner MM, Finlay BB. Quorum sensing in bacterial virulence. Microbiology (Reading, England). 156: 2271-82. PMID 20488878 DOI: 10.1099/mic.0.038794-0  0.302
2010 Bergstrom KS, Kissoon-Singh V, Gibson DL, Ma C, Montero M, Sham HP, Ryz N, Huang T, Velcich A, Finlay BB, Chadee K, Vallance BA. Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. Plos Pathogens. 6: e1000902. PMID 20485566 DOI: 10.1371/journal.ppat.1000902  0.342
2010 Shames SR, Deng W, Guttman JA, de Hoog CL, Li Y, Hardwidge PR, Sham HP, Vallance BA, Foster LJ, Finlay BB. The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling. Cellular Microbiology. 12: 1322-39. PMID 20374249 DOI: 10.1111/J.1462-5822.2010.01470.X  0.432
2010 Chattopadhyay A, Robinson N, Sandhu JK, Finlay BB, Sad S, Krishnan L. Salmonella enterica serovar Typhimurium-induced placental inflammation and not bacterial burden correlates with pathology and fatal maternal disease. Infection and Immunity. 78: 2292-301. PMID 20194592 DOI: 10.1128/Iai.01186-09  0.323
2010 Bhavsar AP, Auweter SD, Finlay BB. Proteomics as a probe of microbial pathogenesis and its molecular boundaries. Future Microbiology. 5: 253-65. PMID 20143948 DOI: 10.2217/fmb.09.114  0.327
2010 Früh K, Finlay B, McFadden G. On the road to systems biology of host-pathogen interactions. Future Microbiology. 5: 131-3. PMID 20143936 DOI: 10.2217/Fmb.09.130  0.412
2010 Deng W, de Hoog CL, Yu HB, Li Y, Croxen MA, Thomas NA, Puente JL, Foster LJ, Finlay BB. A comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium. The Journal of Biological Chemistry. 285: 6790-800. PMID 20034934 DOI: 10.1074/jbc.M109.086603  0.413
2010 Croxen MA, Finlay BB. Molecular mechanisms of Escherichia coli pathogenicity. Nature Reviews. Microbiology. 8: 26-38. PMID 19966814 DOI: 10.1038/nrmicro2265  0.318
2010 Guttman JA, Lin AE, Li Y, Bechberger J, Naus CC, Vogl AW, Finlay BB. Gap junction hemichannels contribute to the generation of diarrhoea during infectious enteric disease. Gut. 59: 218-26. PMID 19828465 DOI: 10.1136/Gut.2008.170464  0.36
2009 Gao X, Wan F, Mateo K, Callegari E, Wang D, Deng W, Puente J, Li F, Chaussee MS, Finlay BB, Lenardo MJ, Hardwidge PR. Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function. Plos Pathogens. 5: e1000708. PMID 20041225 DOI: 10.1371/Journal.Ppat.1000708  0.375
2009 Menendez A, Arena ET, Guttman JA, Thorson L, Vallance BA, Vogl W, Finlay BB. Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever. The Journal of Infectious Diseases. 200: 1703-13. PMID 19852670 DOI: 10.1086/646608  0.338
2009 Albaghdadi H, Robinson N, Finlay B, Krishnan L, Sad S. Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response. Journal of Immunology (Baltimore, Md. : 1950). 183: 3778-87. PMID 19692639 DOI: 10.4049/Jimmunol.0900843  0.419
2009 Sekirov I, Finlay BB. The role of the intestinal microbiota in enteric infection. The Journal of Physiology. 587: 4159-67. PMID 19491248 DOI: 10.1113/jphysiol.2009.172742  0.365
2009 Sal-Man N, Biemans-Oldehinkel E, Finlay BB. Structural microengineers: pathogenic Escherichia coli redesigns the actin cytoskeleton in host cells. Structure (London, England : 1993). 17: 15-9. PMID 19141278 DOI: 10.1016/j.str.2008.12.001  0.441
2009 Guttman JA, Finlay BB. Tight junctions as targets of infectious agents. Biochimica Et Biophysica Acta. 1788: 832-41. PMID 19059200 DOI: 10.1016/J.Bbamem.2008.10.028  0.326
2008 Auweter SD, Bhavsar AP, Finlay BB. Host factor reveals the intrinsic enzymatic activity of a bacterial effector. Future Microbiology. 3: 617-20. PMID 19072178 DOI: 10.2217/17460913.3.6.617  0.336
2008 Guttman JA, Finlay BB. Subcellular alterations that lead to diarrhea during bacterial pathogenesis. Trends in Microbiology. 16: 535-42. PMID 18819802 DOI: 10.1016/J.Tim.2008.08.004  0.378
2008 Shames SR, Auweter SD, Finlay BB. Co-evolution and exploitation of host cell signaling pathways by bacterial pathogens. The International Journal of Biochemistry & Cell Biology. 41: 380-9. PMID 18775503 DOI: 10.1016/j.biocel.2008.08.013  0.42
2008 Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH. SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. The Journal of Cell Biology. 182: 741-52. PMID 18725540 DOI: 10.1083/Jcb.200804131  0.619
2008 Sekirov I, Tam NM, Jogova M, Robertson ML, Li Y, Lupp C, Finlay BB. Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infection and Immunity. 76: 4726-36. PMID 18678663 DOI: 10.1128/IAI.00319-08  0.351
2008 Konczy P, Ziebell K, Mascarenhas M, Choi A, Michaud C, Kropinski AM, Whittam TS, Wickham M, Finlay B, Karmali MA. Genomic O island 122, locus for enterocyte effacement, and the evolution of virulent verocytotoxin-producing Escherichia coli. Journal of Bacteriology. 190: 5832-40. PMID 18586943 DOI: 10.1128/Jb.00480-08  0.325
2008 Rogers LD, Kristensen AR, Boyle EC, Robinson DP, Ly RT, Finlay BB, Foster LJ. Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD. Journal of Proteomics. 71: 97-108. PMID 18541478 DOI: 10.1016/j.jprot.2008.01.011  0.403
2008 Zarivach R, Deng W, Vuckovic M, Felise HB, Nguyen HV, Miller SI, Finlay BB, Strynadka NC. Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature. 453: 124-7. PMID 18451864 DOI: 10.1038/Nature06832  0.387
2008 Sad S, Dudani R, Gurnani K, Russell M, van Faassen H, Finlay B, Krishnan L. Pathogen proliferation governs the magnitude but compromises the function of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 5853-61. PMID 18424704 DOI: 10.4049/Jimmunol.180.9.5853  0.372
2008 Valdez Y, Diehl GE, Vallance BA, Grassl GA, Guttman JA, Brown NF, Rosenberger CM, Littman DR, Gros P, Finlay BB. Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular Microbiology. 10: 1646-61. PMID 18397382 DOI: 10.1111/J.1462-5822.2008.01155.X  0.695
2008 Gal-Mor O, Gibson DL, Baluta D, Vallance BA, Finlay BB. A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis. Plos Pathogens. 4: e1000036. PMID 18389060 DOI: 10.1371/journal.ppat.1000036  0.401
2008 Echtenkamp F, Deng W, Wickham ME, Vazquez A, Puente JL, Thanabalasuriar A, Gruenheid S, Finlay BB, Hardwidge PR. Characterization of the NleF effector protein from attaching and effacing bacterial pathogens. Fems Microbiology Letters. 281: 98-107. PMID 18279332 DOI: 10.1111/J.1574-6968.2008.01088.X  0.448
2008 White AP, Gibson DL, Grassl GA, Kay WW, Finlay BB, Vallance BA, Surette MG. Aggregation via the red, dry, and rough morphotype is not a virulence adaptation in Salmonella enterica serovar Typhimurium. Infection and Immunity. 76: 1048-58. PMID 18195033 DOI: 10.1128/Iai.01383-07  0.305
2007 Lupp C, Robertson ML, Wickham ME, Sekirov I, Champion OL, Gaynor EC, Finlay BB. Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host & Microbe. 2: 204. PMID 18030708 DOI: 10.1016/j.chom.2007.08.002  0.332
2007 Veiga E, Guttman JA, Bonazzi M, Boucrot E, Toledo-Arana A, Lin AE, Enninga J, Pizarro-Cerdá J, Finlay BB, Kirchhausen T, Cossart P. Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host & Microbe. 2: 340-51. PMID 18005755 DOI: 10.1016/J.Chom.2007.10.001  0.471
2007 Kim J, Thanabalasuriar A, Chaworth-Musters T, Fromme JC, Frey EA, Lario PI, Metalnikov P, Rizg K, Thomas NA, Lee SF, Hartland EL, Hardwidge PR, Pawson T, Strynadka NC, Finlay BB, et al. The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. Cell Host & Microbe. 2: 160-71. PMID 18005731 DOI: 10.1016/J.Chom.2007.07.010  0.415
2007 Lupp C, Robertson ML, Wickham ME, Sekirov I, Champion OL, Gaynor EC, Finlay BB. Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host & Microbe. 2: 119-29. PMID 18005726 DOI: 10.1016/j.chom.2007.06.010  0.332
2007 Bhavsar AP, Guttman JA, Finlay BB. Manipulation of host-cell pathways by bacterial pathogens. Nature. 449: 827-34. PMID 17943119 DOI: 10.1038/nature06247  0.413
2007 Coburn B, Sekirov I, Finlay BB. Type III secretion systems and disease. Clinical Microbiology Reviews. 20: 535-49. PMID 17934073 DOI: 10.1128/CMR.00013-07  0.431
2007 Boyle EC, Brown NF, Brumell JH, Finlay BB. Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells. Microbiology (Reading, England). 153: 3517-26. PMID 17906149 DOI: 10.1099/Mic.0.2007/008581-0  0.66
2007 Bakowski MA, Cirulis JT, Brown NF, Finlay BB, Brumell JH. SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion. Cellular Microbiology. 9: 2839-55. PMID 17696999 DOI: 10.1111/J.1462-5822.2007.01000.X  0.681
2007 Thomas NA, Deng W, Baker N, Puente J, Finlay BB. Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli. The Journal of Biological Chemistry. 282: 29634-45. PMID 17681945 DOI: 10.1074/jbc.M706019200  0.391
2007 Wickham ME, Brown NF, Boyle EC, Coombes BK, Finlay BB. Virulence is positively selected by transmission success between mammalian hosts. Current Biology : Cb. 17: 783-8. PMID 17442572 DOI: 10.1016/J.Cub.2007.03.067  0.418
2007 Guttman JA, Kazemi P, Lin AE, Vogl AW, Finlay BB. Desmosomes are unaltered during infections by attaching and effacing pathogens. Anatomical Record (Hoboken, N.J. : 2007). 290: 199-205. PMID 17441212 DOI: 10.1002/ar.20414  0.394
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. The Journal of General Physiology. 129: 267-83. PMID 17389247 DOI: 10.1085/Jgp.200609656  0.655
2007 Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donini O, Guarna MM, Finlay BB, et al. An anti-infective peptide that selectively modulates the innate immune response. Nature Biotechnology. 25: 465-72. PMID 17384586 DOI: 10.1038/Nbt1288  0.314
2007 Wickham ME, Lupp C, Vázquez A, Mascarenhas M, Coburn B, Coombes BK, Karmali MA, Puente JL, Deng W, Finlay BB. Citrobacter rodentium virulence in mice associates with bacterial load and the type III effector NleE. Microbes and Infection / Institut Pasteur. 9: 400-7. PMID 17317262 DOI: 10.1016/J.Micinf.2006.12.016  0.336
2007 Zarivach R, Vuckovic M, Deng W, Finlay BB, Strynadka NC. Structural analysis of a prototypical ATPase from the type III secretion system. Nature Structural & Molecular Biology. 14: 131-7. PMID 17237797 DOI: 10.1038/nsmb1196  0.355
2007 Coombes BK, Lowden MJ, Bishop JL, Wickham ME, Brown NF, Duong N, Osborne S, Gal-Mor O, Finlay BB. SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system. Infection and Immunity. 75: 574-80. PMID 17158898 DOI: 10.1128/Iai.00985-06  0.476
2007 Guttman JA, Samji FN, Li Y, Deng W, Lin A, Finlay BB. Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens. Cellular Microbiology. 9: 131-41. PMID 16889624 DOI: 10.1111/j.1462-5822.2006.00773.x  0.37
2006 Goosney DL, Kujat Choy SL, Finlay BB. Salmonella and Enteropathogenic Escherichia coli Interactions with Host Cells: Signaling Pathways. Ecosal Plus. 2. PMID 26443572 DOI: 10.1128/ecosalplus.8.8.4  0.812
2006 Guttman JA, Samji FN, Li Y, Vogl AW, Finlay BB. Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo. Infection and Immunity. 74: 6075-84. PMID 16954399 DOI: 10.1128/IAI.00721-06  0.341
2006 Gal-Mor O, Finlay BB. Pathogenicity islands: a molecular toolbox for bacterial virulence. Cellular Microbiology. 8: 1707-19. PMID 16939533 DOI: 10.1111/j.1462-5822.2006.00794.x  0.343
2006 Boyle EC, Brown NF, Finlay BB. Salmonella enterica serovar Typhimurium effectors SopB, SopE, SopE2 and SipA disrupt tight junction structure and function. Cellular Microbiology. 8: 1946-57. PMID 16869830 DOI: 10.1111/j.1462-5822.2006.00762.x  0.382
2006 Brown NF, Szeto J, Jiang X, Coombes BK, Finlay BB, Brumell JH. Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function. Microbiology (Reading, England). 152: 2323-43. PMID 16849798 DOI: 10.1099/Mic.0.28995-0  0.639
2006 Gal-Mor O, Valdez Y, Finlay BB. The temperature-sensing protein TlpA is repressed by PhoP and dispensable for virulence of Salmonella enterica serovar Typhimurium in mice. Microbes and Infection. 8: 2154-62. PMID 16782389 DOI: 10.1016/J.MICINF.2006.04.015  0.363
2006 Ma C, Wickham ME, Guttman JA, Deng W, Walker J, Madsen KL, Jacobson K, Vogl WA, Finlay BB, Vallance BA. Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map). Cellular Microbiology. 8: 1669-86. PMID 16759225 DOI: 10.1111/J.1462-5822.2006.00741.X  0.326
2006 Brown NF, Wickham ME, Coombes BK, Finlay BB. Crossing the line: selection and evolution of virulence traits. Plos Pathogens. 2: e42. PMID 16733541 DOI: 10.1371/Journal.Ppat.0020042  0.312
2006 Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, Finlay BB, Vallance BA. Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infection and Immunity. 74: 2522-36. PMID 16622187 DOI: 10.1128/Iai.74.5.2522-2536.2006  0.733
2006 Guttman JA, Li Y, Wickham ME, Deng W, Vogl AW, Finlay BB. Attaching and effacing pathogen-induced tight junction disruption in vivo. Cellular Microbiology. 8: 634-45. PMID 16548889 DOI: 10.1111/j.1462-5822.2005.00656.x  0.36
2006 Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/Np050192H  0.708
2006 Finlay BB, McFadden G. Anti-immunology: Evasion of the host immune system by bacterial and viral pathogens Cell. 124: 767-782. PMID 16497587 DOI: 10.1016/J.Cell.2006.01.034  0.368
2006 Martin-Orozco N, Touret N, Zaharik ML, Park E, Kopelman R, Miller S, Finlay BB, Gros P, Grinstein S. Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Molecular Biology of the Cell. 17: 498-510. PMID 16251362 DOI: 10.1091/Mbc.E04-12-1096  0.784
2005 Brown NF, Vallance BA, Coombes BK, Valdez Y, Coburn BA, Finlay BB. Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine. Plos Pathogens. 1: e32. PMID 16304611 DOI: 10.1371/Journal.Ppat.0010032  0.352
2005 Coombes BK, Wickham ME, Lowden MJ, Brown NF, Finlay BB. Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proceedings of the National Academy of Sciences of the United States of America. 102: 17460-5. PMID 16301528 DOI: 10.1073/Pnas.0505401102  0.394
2005 Gauthier A, Robertson ML, Lowden M, Ibarra JA, Puente JL, Finlay BB. Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli. Antimicrobial Agents and Chemotherapy. 49: 4101-9. PMID 16189086 DOI: 10.1128/Aac.49.10.4101-4109.2005  0.761
2005 Rodríguez-Escudero I, Hardwidge PR, Nombela C, Cid VJ, Finlay BB, Molina M. Enteropathogenic Escherichia coli type III effectors alter cytoskeletal function and signalling in Saccharomyces cerevisiae. Microbiology (Reading, England). 151: 2933-45. PMID 16151205 DOI: 10.1099/Mic.0.28072-0  0.334
2005 Thomas NA, Deng W, Puente JL, Frey EA, Yip CK, Strynadka NC, Finlay BB. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. Molecular Microbiology. 57: 1762-79. PMID 16135239 DOI: 10.1111/j.1365-2958.2005.04802.x  0.39
2005 Coburn B, Li Y, Owen D, Vallance BA, Finlay BB. Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infection and Immunity. 73: 3219-27. PMID 15908346 DOI: 10.1128/IAI.73.6.3219-3227.2005  0.322
2005 Hardwidge PR, Deng W, Vallance BA, Rodriguez-Escudero I, Cid VJ, Molina M, Finlay BB. Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG. Infection and Immunity. 73: 2586-94. PMID 15845460 DOI: 10.1128/Iai.73.5.2586-2594.2005  0.421
2005 Coombes BK, Wickham ME, Brown NF, Lemire S, Bossi L, Hsiao WW, Brinkman FS, Finlay BB. Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage. Journal of Molecular Biology. 348: 817-30. PMID 15843015 DOI: 10.1016/J.Jmb.2005.03.024  0.436
2005 Deng W, Li Y, Hardwidge PR, Frey EA, Pfuetzner RA, Lee S, Gruenheid S, Strynakda NC, Puente JL, Finlay BB. Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. Infection and Immunity. 73: 2135-46. PMID 15784556 DOI: 10.1128/Iai.73.4.2135-2146.2005  0.391
2005 Coombes BK, Finlay BB. Insertion of the bacterial type III translocon: not your average needle stick. Trends in Microbiology. 13: 92-5. PMID 15737725 DOI: 10.1016/J.Tim.2005.01.008  0.404
2005 Knodler LA, Finlay BB, Steele-Mortimer O. The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. The Journal of Biological Chemistry. 280: 9058-64. PMID 15642738 DOI: 10.1074/JBC.M412588200  0.385
2005 Yip CK, Finlay BB, Strynadka NC. Structural characterization of a type III secretion system filament protein in complex with its chaperone. Nature Structural & Molecular Biology. 12: 75-81. PMID 15619638 DOI: 10.1038/nsmb879  0.326
2004 Jiang X, Rossanese OW, Brown NF, Kujat-Choy S, Galán JE, Finlay BB, Brumell JH. The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Molecular Microbiology. 54: 1186-98. PMID 15554961 DOI: 10.1111/J.1365-2958.2004.04344.X  0.664
2004 Coombes BK, Valdez Y, Finlay BB. Evasive maneuvers by secreted bacterial proteins to avoid innate immune responses. Current Biology : Cb. 14: R856-67. PMID 15458668 DOI: 10.1016/J.Cub.2004.09.043  0.343
2004 Coombes BK, Brown NF, Valdez Y, Brumell JH, Finlay BB. Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL. The Journal of Biological Chemistry. 279: 49804-15. PMID 15383528 DOI: 10.1074/Jbc.M404299200  0.634
2004 Zaharik ML, Cullen VL, Fung AM, Libby SJ, Kujat Choy SL, Coburn B, Kehres DG, Maguire ME, Fang FC, Finlay BB. The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model. Infection and Immunity. 72: 5522-5. PMID 15322058 DOI: 10.1128/Iai.72.9.5522-5525.2004  0.793
2004 Kujat Choy SL, Boyle EC, Gal-Mor O, Goode DL, Valdez Y, Vallance BA, Finlay BB. SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium. Infection and Immunity. 72: 5115-25. PMID 15322005 DOI: 10.1128/IAI.72.9.5115-5125.2004  0.399
2004 Coombes BK, Hardwidge PR, Finlay BB. Interpreting the host-pathogen dialogue through microarrays. Advances in Applied Microbiology. 54: 291-331. PMID 15251285 DOI: 10.1016/S0065-2164(04)54011-X  0.42
2004 Pollard AJ, Currie A, Rosenberger CM, Heale JP, Finlay BB, Speert DP. Differential post-transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates. Cellular Microbiology. 6: 639-50. PMID 15186400 DOI: 10.1111/J.1462-5822.2004.00388.X  0.664
2004 Bertelsen LS, Paesold G, Marcus SL, Finlay BB, Eckmann L, Barrett KE. Modulation of chloride secretory responses and barrier function of intestinal epithelial cells by the Salmonella effector protein SigD. American Journal of Physiology. Cell Physiology. 287: C939-48. PMID 15175224 DOI: 10.1152/ajpcell.00413.2003  0.356
2004 Harrison RE, Brumell JH, Khandani A, Bucci C, Scott CC, Jiang X, Finlay BB, Grinstein S. Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Molecular Biology of the Cell. 15: 3146-54. PMID 15121880 DOI: 10.1091/Mbc.E04-02-0092  0.7
2004 Deng W, Puente JL, Gruenheid S, Li Y, Vallance BA, Vázquez A, Barba J, Ibarra JA, O'Donnell P, Metalnikov P, Ashman K, Lee S, Goode D, Pawson T, Finlay BB. Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proceedings of the National Academy of Sciences of the United States of America. 101: 3597-602. PMID 14988506 DOI: 10.1073/Pnas.0400326101  0.417
2004 Hardwidge PR, Rodriguez-Escudero I, Goode D, Donohoe S, Eng J, Goodlett DR, Aebersold R, Finlay BB. Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli. The Journal of Biological Chemistry. 279: 20127-36. PMID 14988394 DOI: 10.1074/Jbc.M401228200  0.407
2004 Rosenberger CM, Gallo RL, Finlay BB. Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proceedings of the National Academy of Sciences of the United States of America. 101: 2422-7. PMID 14983025 DOI: 10.1073/Pnas.0304455101  0.693
2004 Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB. Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Molecular Microbiology. 51: 1233-49. PMID 14982621 DOI: 10.1046/J.1365-2958.2003.03911.X  0.422
2004 Zaharik ML, Finlay BB. Mn2+ and bacterial pathogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1035-42. PMID 14977526 DOI: 10.2741/1317  0.798
2004 Boyle EC, Finlay BB. Bacterial pathogenesis: exploiting cellular adherence. Current Opinion in Cell Biology. 15: 633-9. PMID 14519399 DOI: 10.1016/S0955-0674(03)00099-1  0.332
2004 Colburn BA, Finlay BB. BACTERIAL EFFECTORS AND THE EVASION OF HOST DEFENSES IN SALMONELLA INFECTION. Journal of Investigative Medicine. 52: S140. DOI: 10.1097/00042871-200401001-00348  0.38
2003 Gauthier A, Finlay BB. Translocated intimin receptor and its chaperone interact with ATPase of the type III secretion apparatus of enteropathogenic Escherichia coli. Journal of Bacteriology. 185: 6747-55. PMID 14617638 DOI: 10.1128/Jb.185.23.6747-6755.2003  0.743
2003 Knodler LA, Vallance BA, Hensel M, Jäckel D, Finlay BB, Steele-Mortimer O. Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes. Molecular Microbiology. 49: 685-704. PMID 12864852 DOI: 10.1046/j.1365-2958.2003.03598.x  0.41
2003 Coombes BK, Brown NF, Kujat-Choy S, Vallance BA, Finlay BB. SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells. Microbes and Infection / Institut Pasteur. 5: 561-70. PMID 12787732 DOI: 10.1016/S1286-4579(03)00094-7  0.42
2003 Vallance BA, Deng W, Jacobson K, Finlay BB. Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium. Infection and Immunity. 71: 3443-53. PMID 12761129 DOI: 10.1128/IAI.71.6.3443-3453.2003  0.316
2003 Gauthier A, Puente JL, Finlay BB. Secretin of the enteropathogenic Escherichia coli type III secretion system requires components of the type III apparatus for assembly and localization. Infection and Immunity. 71: 3310-9. PMID 12761113 DOI: 10.1128/Iai.71.6.3310-3319.2003  0.753
2003 Gauthier A, Thomas NA, Finlay BB. Bacterial injection machines. The Journal of Biological Chemistry. 278: 25273-6. PMID 12759358 DOI: 10.1074/Jbc.R300012200  0.711
2003 Rosenberger CM, Finlay BB. Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nature Reviews. Molecular Cell Biology. 4: 385-96. PMID 12728272 DOI: 10.1038/Nrm1104  0.727
2003 Gruenheid S, Finlay BB. Microbial pathogenesis and cytoskeletal function. Nature. 422: 775-81. PMID 12700772 DOI: 10.1038/Nature01603  0.389
2003 Kurz CL, Chauvet S, Andrès E, Aurouze M, Vallet I, Michel GPF, Uh M, Celli J, Filloux A, De Bentzmann S, Steinmetz I, Hoffmann JA, Finlay BB, Gorvel JP, Ferrandon D, et al. Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Embo Journal. 22: 1451-1460. PMID 12660152 DOI: 10.1093/Emboj/Cdg159  0.369
2003 Deng W, Vallance BA, Li Y, Puente JL, Finlay BB. Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice. Molecular Microbiology. 48: 95-115. PMID 12657048 DOI: 10.1046/j.1365-2958.2003.03429.x  0.35
2003 Brumell JH, Kujat-Choy S, Brown NF, Vallance BA, Knodler LA, Finlay BB. SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells. Traffic (Copenhagen, Denmark). 4: 36-48. PMID 12535274 DOI: 10.1034/j.1600-0854.2003.40106.x  0.688
2002 Vallance BA, Chan C, Robertson ML, Finlay BB. Enteropathogenic and enterohemorrhagic Escherichia coli infections: emerging themes in pathogenesis and prevention. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 16: 771-8. PMID 12464970  0.324
2002 Zaharik ML, Vallance BA, Puente JL, Gros P, Finlay BB. Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 15705-10. PMID 12441401 DOI: 10.1073/Pnas.252415599  0.831
2002 Linington RG, Robertson M, Gauthier A, Finlay BB, van Soest R, Andersen RJ. Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. Organic Letters. 4: 4089-92. PMID 12423093 DOI: 10.1021/Ol0268337  0.718
2002 Vallance BA, Deng W, De Grado M, Chan C, Jacobson K, Finlay BB. Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice. Infection and Immunity. 70: 6424-35. PMID 12379723 DOI: 10.1128/IAI.70.11.6424-6435.2002  0.392
2002 Terebiznik MR, Vieira OV, Marcus SL, Slade A, Yip CM, Trimble WS, Meyer T, Finlay BB, Grinstein S. Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nature Cell Biology. 4: 766-73. PMID 12360287 DOI: 10.1038/Ncb854  0.478
2002 Marcus SL, Knodler LA, Finlay BB. Salmonella enterica serovar Typhimurium effector SigD/SopB is membrane-associated and ubiquitinated inside host cells. Cellular Microbiology. 4: 435-46. PMID 12102689 DOI: 10.1046/j.1462-5822.2002.00202.x  0.408
2002 Brumell JH, Tang P, Zaharik ML, Finlay BB. Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infection and Immunity. 70: 3264-70. PMID 12011022 DOI: 10.1128/Iai.70.6.3264-3270.2002  0.833
2002 Brumell JH, Goosney DL, Finlay BB. SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules. Traffic (Copenhagen, Denmark). 3: 407-15. PMID 12010459 DOI: 10.1034/J.1600-0854.2002.30604.X  0.834
2002 Zaharik ML, Gruenheid S, Perrin AJ, Finlay BB. Delivery of dangerous goods: type III secretion in enteric pathogens. International Journal of Medical Microbiology : Ijmm. 291: 593-603. PMID 12008913 DOI: 10.1078/1438-4221-00179  0.838
2002 Celli J, Finlay BB. Bacterial avoidance of phagocytosis. Trends in Microbiology. 10: 232-7. PMID 11973157 DOI: 10.1016/S0966-842X(02)02343-0  0.366
2002 Knodler LA, Celli J, Hardt WD, Vallance BA, Yip C, Finlay BB. Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Molecular Microbiology. 43: 1089-103. PMID 11918798 DOI: 10.1046/J.1365-2958.2002.02820.X  0.434
2002 Vallance BA, Deng W, Knodler LA, Finlay BB. Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infection and Immunity. 70: 2070-81. PMID 11895973 DOI: 10.1128/IAI.70.4.2070-2081.2002  0.307
2002 Steele-Mortimer O, Brumell JH, Knodler LA, Méresse S, Lopez A, Finlay BB. The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells. Cellular Microbiology. 4: 43-54. PMID 11856172 DOI: 10.1046/j.1462-5822.2002.00170.x  0.674
2002 Rosenberger CM, Finlay BB. Macrophages inhibit Salmonella typhimurium replication through MEK/ERK kinase and phagocyte NADPH oxidase activities. The Journal of Biological Chemistry. 277: 18753-62. PMID 11821396 DOI: 10.1074/Jbc.M110649200  0.725
2002 Brumell JH, Perrin AJ, Goosney DL, Finlay BB. Microbial pathogenesis: New niches for Salmonella Current Biology. 12: R15-R17. PMID 11790317 DOI: 10.1016/S0960-9822(01)00640-6  0.831
2002 Knodler LA, Finlay BB. Salmonella and apoptosis: to live or let die? Microbes and Infection. 3: 1321-6. PMID 11755421 DOI: 10.1016/S1286-4579(01)01493-9  0.388
2001 Rosenberger CM, Pollard AJ, Finlay BB. Gene array technology to determine host responses to Salmonella. Microbes and Infection / Institut Pasteur. 3: 1353-60. PMID 11755425 DOI: 10.1016/S1286-4579(01)01497-6  0.703
2001 Cuellar-Mata P, Jabado N, Liu J, Furuya W, Finlay BB, Gros P, Grinstein S. Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. The Journal of Biological Chemistry. 277: 2258-65. PMID 11700301 DOI: 10.1074/jbc.M105508200  0.573
2001 DeVinney R, Puente JL, Gauthier A, Goosney D, Finlay BB. Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation. Molecular Microbiology. 41: 1445-58. PMID 11580847 DOI: 10.1046/J.1365-2958.2001.02617.X  0.821
2001 Brumell JH, Tang P, Mills SD, Finlay BB. Characterization of Salmonella-induced filaments (Sifs) reveals a delayed interaction between Salmonella-containing vacuoles and late endocytic compartments Traffic. 2: 643-653. PMID 11555418 DOI: 10.1034/j.1600-0854.2001.20907.x  0.658
2001 de Grado M, Rosenberger CM, Gauthier A, Vallance BA, Finlay BB. Enteropathogenic Escherichia coli infection induces expression of the early growth response factor by activating mitogen-activated protein kinase cascades in epithelial cells. Infection and Immunity. 69: 6217-24. PMID 11553563 DOI: 10.1128/Iai.69.10.6217-6224.2001  0.827
2001 Gruenheid S, DeVinney R, Bladt F, Goosney D, Gelkop S, Gish GD, Pawson T, Finlay BB. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells Nature Cell Biology. 3: 856-859. PMID 11533668 DOI: 10.1038/Ncb0901-856  0.818
2001 Knodler LA, Celli J, Finlay BB. Pathogenic trickery: deception of host cell processes. Nature Reviews. Molecular Cell Biology. 2: 578-88. PMID 11483991 DOI: 10.1038/35085062  0.378
2001 Gauthier A, Finlay BB. Bacterial pathogenesis: the answer to virulence is in the pore. Current Biology : Cb. 11: R264-7. PMID 11413015 DOI: 10.1016/S0960-9822(01)00134-8  0.808
2001 Goosney DL, DeVinney R, Finlay BB. Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals. Infection and Immunity. 69: 3315-22. PMID 11292754 DOI: 10.1128/Iai.69.5.3315-3322.2001  0.798
2001 Celli J, Olivier M, Finlay BB. Enteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3-kinase-dependent pathways. The Embo Journal. 20: 1245-58. PMID 11250891 DOI: 10.1093/Emboj/20.6.1245  0.306
2001 Steele-Mortimer O, Knodler LA, Finlay BB. Poisons, ruffles and rockets: bacterial pathogens and the host cell cytoskeleton. Traffic (Copenhagen, Denmark). 1: 107-18. PMID 11208091 DOI: 10.1034/j.1600-0854.2000.010203.x  0.459
2001 Brumell JH, Rosenberger CM, Gotto GT, Marcus SL, Finlay BB. SifA permits survival and replication of Salmonella typhimurium in murine macrophages. Cellular Microbiology. 3: 75-84. PMID 11207622 DOI: 10.1046/J.1462-5822.2001.00087.X  0.811
2001 Celli J, Deng W, Finlay BB. Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside. Cellular Microbiology. 2: 1-9. PMID 11207558 DOI: 10.1046/j.1462-5822.2000.00033.x  0.461
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/Jbc.M007792200  0.703
2000 Rosenberger CM, Brumell JH, Finlay BB. Microbial pathogenesis: lipid rafts as pathogen portals. Current Biology : Cb. 10: R823-5. PMID 11102822 DOI: 10.1016/S0960-9822(00)00788-0  0.791
2000 Goosney DL, Gruenheid S, Finlay BB. Gut feelings: Enteropathogenic E. coli (EPEC) interactions with the host Annual Review of Cell and Developmental Biology. 16: 173-189. PMID 11031234 DOI: 10.1146/Annurev.Cellbio.16.1.173  0.823
2000 Scott MG, Rosenberger CM, Gold MR, Finlay BB, Hancock RE. An alpha-helical cationic antimicrobial peptide selectively modulates macrophage responses to lipopolysaccharide and directly alters macrophage gene expression. Journal of Immunology (Baltimore, Md. : 1950). 165: 3358-65. PMID 10975854 DOI: 10.4049/Jimmunol.165.6.3358  0.649
2000 Steele-Mortimer O, St-Louis M, Olivier M, Finlay BB. Vacuole Acidification is not required for survival of Salmonella enterica serovar Typhimurium within cultured macrophages and epithelial cells Infection and Immunity. 68: 5401-5404. PMID 10948170 DOI: 10.1128/Iai.68.9.5401-5404.2000  0.319
2000 Li Y, Frey E, Mackenzie AM, Finlay BB. Human response to Escherichia coli O157:H7 infection: antibodies to secreted virulence factors. Infection and Immunity. 68: 5090-5. PMID 10948130 DOI: 10.1128/IAI.68.9.5090-5095.2000  0.319
2000 Vallance BA, Finlay BB. Exploitation of host cells by enteropathogenic Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 97: 8799-806. PMID 10922038 DOI: 10.1073/PNAS.97.16.8799  0.486
2000 Luo Y, Frey EA, Pfuetzner RA, Creagh AL, Knoechel DG, Haynes CA, Finlay BB, Strynadka NC. Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex. Nature. 405: 1073-7. PMID 10890451 DOI: 10.1038/35016618  0.358
2000 Finlay BB, Brumell JH. Salmonella interactions with host cells: In vitro to in vivo Philosophical Transactions of the Royal Society B: Biological Sciences. 355: 623-631. PMID 10874735  0.569
2000 Goosney DL, DeVinney R, Pfuetzner RA, Frey EA, Strynadka NC, Finlay BB. Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin. Current Biology : Cb. 10: 735-8. PMID 10873808 DOI: 10.1016/S0960-9822(00)00543-1  0.8
2000 Gauthier A, de Grado M, Finlay BB. Mechanical fractionation reveals structural requirements for enteropathogenic Escherichia coli Tir insertion into host membranes. Infection and Immunity. 68: 4344-8. PMID 10858257 DOI: 10.1128/Iai.68.7.4344-4348.2000  0.804
2000 Kehres DG, Zaharik ML, Finlay BB, Maguire ME. The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen. Molecular Microbiology. 36: 1085-100. PMID 10844693 DOI: 10.1046/J.1365-2958.2000.01922.X  0.796
2000 Brumell JH, Marcus SL, Finlay BB. N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium. Molecular Microbiology. 36: 773-4. PMID 10844665 DOI: 10.1046/j.1365-2958.2000.01878.x  0.543
2000 Rosenberger CM, Scott MG, Gold MR, Hancock RE, Finlay BB. Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression. Journal of Immunology (Baltimore, Md. : 1950). 164: 5894-904. PMID 10820271 DOI: 10.4049/Jimmunol.164.11.5894  0.718
2000 Tacket CO, Sztein MB, Losonsky G, Abe A, Finlay BB, McNamara BP, Fantry GT, James SP, Nataro JP, Levine MM, Donnenberg MS. Role of EspB in experimental human enteropathogenic Escherichia coli infection Infection and Immunity. 68: 3689-3695. PMID 10816529 DOI: 10.1128/Iai.68.6.3689-3695.2000  0.306
2000 Marcus SL, Brumell JH, Pfeifer CG, Finlay BB. Salmonella pathogenicity islands: big virulence in small packages. Microbes and Infection / Institut Pasteur. 2: 145-56. PMID 10742687 DOI: 10.1016/S1286-4579(00)00273-2  0.619
2000 Heczko U, Abe A, Finlay BB. In vivo interactions of rabbit enteropathogenic Escherichia coli O103 with its host: an electron microscopic and histopathologic study. Microbes and Infection. 2: 5-16. PMID 10717535 DOI: 10.1016/S1286-4579(00)00291-4  0.316
2000 DeVinney R, Steele-Mortimer O, Finlay BB. Phosphatases and kinases delivered to the host cell by bacterial pathogens. Trends in Microbiology. 8: 29-33. PMID 10637641 DOI: 10.1016/S0966-842X(99)01657-1  0.439
2000 Finlay B. Pathogenicity Islands Cell. 101: 134-135. DOI: 10.1016/S0092-8674(00)80814-4  0.349
1999 de Grado M, Abe A, Gauthier A, Steele-Mortimer O, DeVinney R, Finlay BB. Identification of the intimin-binding domain of Tir of enteropathogenic Escherichia coli. Cellular Microbiology. 1: 7-17. PMID 11207537 DOI: 10.1046/J.1462-5822.1999.00001.X  0.775
1999 Méresse S, Steele-Mortimer O, Moreno E, Desjardins M, Finlay B, Gorvel J. Controlling the maturation of pathogen-containing vacuoles: a matter of life and death. Nature Cell Biology. 1. PMID 10560000 DOI: 10.1038/15620  0.461
1999 Kalman D, Weiner OD, Goosney DL, Sedat JW, Finlay BB, Abo A, Bishop JM. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nature Cell Biology. 1: 389-91. PMID 10559969 DOI: 10.1038/14087  0.781
1999 Pfeifer CG, Marcus SL, Steele-Mortimer O, Knodler LA, Finlay BB. Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells. Infection and Immunity. 67: 5690-8. PMID 10531217 DOI: 10.1128/IAI.67.11.5690-5698.1999  0.376
1999 Abe A, de Grado M, Pfuetzner RA, Sánchez-Sanmartín C, Devinney R, Puente JL, Strynadka NC, Finlay BB. Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion. Molecular Microbiology. 33: 1162-75. PMID 10510231 DOI: 10.1046/j.1365-2958.1999.01558.x  0.374
1999 Méresse S, Steele-Mortimer O, Finlay BB, Gorvel JP. The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells. The Embo Journal. 18: 4394-403. PMID 10449405 DOI: 10.1093/emboj/18.16.4394  0.359
1999 DeVinney R, Gauthier A, Abe A, Finlay BB. Enteropathogenic Escherichia coli: a pathogen that inserts its own receptor into host cells. Cellular and Molecular Life Sciences : Cmls. 55: 961-76. PMID 10412374 DOI: 10.1007/Pl00013202  0.8
1999 Brumell JH, Steele-Mortimer O, Finlay BB. Bacterial invasion: Force feeding by Salmonella Current Biology. 9. PMID 10226015 DOI: 10.1016/S0960-9822(99)80178-X  0.65
1999 DeVinney R, Stein M, Reinscheid D, Abe A, Ruschkowski S, Finlay BB. Enterohemorrhagic Escherichia coli O157:H7 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated. Infection and Immunity. 67: 2389-98. PMID 10225900 DOI: 10.1128/IAI.67.5.2389-2398.1999  0.408
1999 Govoni G, Canonne-Hergaux F, Pfeifer CG, Marcus SL, Mills SD, Hackam DJ, Grinstein S, Malo D, Finlay BB, Gros P. Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7. Infection and Immunity. 67: 2225-32. PMID 10225878 DOI: 10.1128/Iai.67.5.2225-2232.1999  0.54
1999 Goosney DL, Knoechel DG, Finlay BB. Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation. Emerging Infectious Diseases. 5: 216-23. PMID 10221873 DOI: 10.3201/Eid0502.990205  0.812
1999 Goosney DL, de Grado M, Finlay BB. Putting E. coli on a pedestal: a unique system to study signal transduction and the actin cytoskeleton. Trends in Cell Biology. 9: 11-4. PMID 10087611 DOI: 10.1016/S0962-8924(98)01418-4  0.779
1999 DeVinney R, Knoechel DG, Finlay BB. Enteropathogenic Escherichia coli: cellular harassment. Current Opinion in Microbiology. 2: 83-8. PMID 10047555 DOI: 10.1016/S1369-5274(99)80014-9  0.438
1999 Finlay BB. Bacterial disease in diverse hosts. Cell. 96: 315-8. PMID 10025397 DOI: 10.1016/S0092-8674(00)80544-9  0.308
1999 Goosney DL, Celli J, Kenny B, Finlay BB. Enteropathogenic Escherichia coli inhibits phagocytosis. Infection and Immunity. 67: 490-5. PMID 9916050 DOI: 10.1128/Iai.67.2.490-495.1999  0.804
1998 Gauthier A, Finlay BB. Protein translocation: delivering virulence into the host cell. Current Biology : Cb. 8: R768-70. PMID 9799724 DOI: 10.1016/S0960-9822(07)00482-4  0.801
1998 Richter-Dahlfors A, Meloche RM, Finlay B, Buchan AMJ. Development of Helicobacter pylori-infected human antral primary cell cultures Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)81090-1  0.306
1997 Kenny B, DeVinney R, Stein M, Reinscheid DJ, Frey EA, Finlay BB. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell. 91: 511-20. PMID 9390560 DOI: 10.1016/S0092-8674(00)80437-7  0.44
1997 Mills SD, Boland A, Sory MP, van der Smissen P, Kerbourch C, Finlay BB, Cornelis GR. Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein. Proceedings of the National Academy of Sciences of the United States of America. 94: 12638-43. PMID 9356502 DOI: 10.1073/Pnas.94.23.12638  0.324
1997 Abe A, Kenny B, Stein M, Finlay BB. Characterization of two virulence proteins secreted by rabbit enteropathogenic Escherichia coli, EspA and EspB, whose maximal expression is sensitive to host body temperature. Infection and Immunity. 65: 3547-55. PMID 9284118 DOI: 10.1128/IAI.65.9.3547-3555.1997  0.361
1997 Kenny B, Abe A, Stein M, Finlay BB. Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract. Infection and Immunity. 65: 2606-12. PMID 9199427 DOI: 10.1128/IAI.65.7.2606-2612.1997  0.329
1997 Kenny B, Finlay BB. Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-gamma1. Infection and Immunity. 65: 2528-36. PMID 9199415 DOI: 10.1128/IAI.65.7.2528-2536.1997  0.31
1997 Donnenberg MS, Kaper JB, Finlay BB. Interactions between enteropathogenic Escherichia coli and host epithelial cells Trends in Microbiology. 5: 109-114. PMID 9080609 DOI: 10.1016/S0966-842X(97)01000-7  0.648
1997 Garcia-del Portillo F, Stein MA, Finlay BB. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell Infection and Immunity. 65: 24-34. PMID 8975888 DOI: 10.1128/IAI.65.1.24-34.1997  0.349
1996 Stein M, Kenny B, Stein MA, Finlay BB. Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins Journal of Bacteriology. 178: 6546-6554. PMID 8932311 DOI: 10.1128/Jb.178.22.6546-6554.1996  0.327
1996 Stein MA, Mathers DA, Yan H, Baimbridge KG, Finlay BB. Enteropathogenic Escherichia coli markedly decreases the resting membrane potential of Caco-2 and HeLa human epithelial cells Infection and Immunity. 64: 4820-4825. PMID 8890244 DOI: 10.1128/iai.64.11.4820-4825.1996  0.364
1996 Stein MA, Leung KY, Zwick M, Garcia-del Portillo F, Finlay BB. Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells Molecular Microbiology. 20: 151-164. PMID 8861213 DOI: 10.1111/j.1365-2958.1996.tb02497.x  0.334
1996 Kenny B, Lai LC, Finlay BB, Donnenberg MS. EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells. Molecular Microbiology. 20: 313-23. PMID 8733230 DOI: 10.1111/J.1365-2958.1996.Tb02619.X  0.332
1996 Tang P, Rosenshine I, Cossart P, Finlay BB. Listeriolysin O activates mitogen-activated protein kinase in eucaryotic cells. Infection and Immunity. 64: 2359-61. PMID 8675352 DOI: 10.1128/Iai.64.6.2359-2361.1996  0.367
1996 Rosenshine I, Ruschkowski S, Finlay BB. Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells. Infection and Immunity. 64: 966-73. PMID 8641808 DOI: 10.1128/IAI.64.3.966-973.1996  0.343
1996 Garcia-del Portillo F, Finlay BB. The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments. Trends in Microbiology. 3: 373-80. PMID 8564355 DOI: 10.1016/S0966-842X(00)88982-9  0.406
1995 Garcia-del Portillo F, Finlay BB. Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors. The Journal of Cell Biology. 129: 81-97. PMID 7698996 DOI: 10.1083/JCB.129.1.81  0.356
1995 Kenny B, Finlay BB. Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 7991-5. PMID 7644526 DOI: 10.1073/PNAS.92.17.7991  0.303
1995 Pucciarelli MG, Ruschkowski S, Trust TJ, Finlay BB. Helicobacter pylori induces an increase in inositol phosphates in cultured epithelial cells. Fems Microbiology Letters. 129: 293-9. PMID 7607412 DOI: 10.1111/J.1574-6968.1995.TB07595.X  0.319
1994 Foubister V, Rosenshine I, Finlay BB. A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells. The Journal of Experimental Medicine. 179: 993-8. PMID 8113690 DOI: 10.1084/JEM.179.3.993  0.402
1994 Stein MA, Mills SD, Finlay BB. Salmonella: Now you see it, now you don't Bioessays. 16: 537-538. PMID 8086001 DOI: 10.1002/bies.950160805  0.413
1994 Garcia-del Portillo F, Finlay BB. Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell. Infection and Immunity. 62: 4641-5. PMID 7927733 DOI: 10.1128/IAI.62.10.4641-4645.1994  0.437
1994 Rosenshine I, Ruschkowski S, Foubister V, Finlay BB. Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation. Infection and Immunity. 62: 4969-74. PMID 7523303 DOI: 10.1128/IAI.62.11.4969-4974.1994  0.37
1993 Canil C, Rosenshine I, Ruschkowski S, Donnenberg MS, Kaper JB, Finlay BB. Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers Infection and Immunity. 61: 2755-2762. PMID 8514377 DOI: 10.1128/Iai.61.7.2755-2762.1993  0.509
1993 Rosenshine I, Finlay BB. Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 17-24. PMID 8466472 DOI: 10.1002/BIES.950150104  0.435
1993 Garcia-Del Portillo F, Zwick MB, Leung KY, Finlay BB. Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 90: 10544-10548. PMID 8248143 DOI: 10.1073/PNAS.90.22.10544  0.395
1993 Fierer J, Eckmann L, Fang F, Pfeifer C, Finlay BB, Guiney D. Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells. Infection and Immunity. 61: 5231-6. PMID 8225598 DOI: 10.1128/IAI.61.12.5231-5236.1993  0.32
1993 Betts J, Finlay BB. Identification of Salmonella typhimurium invasiveness loci. Canadian Journal of Microbiology. 38: 852-7. PMID 1458375 DOI: 10.1139/M92-138  0.312
1992 Rosenshine I, Duronio V, Finlay BB. Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells. Infection and Immunity. 60: 2211-7. PMID 1587588 DOI: 10.1128/IAI.60.6.2211-2217.1992  0.415
1992 Rosenshine I, Donnenberg M, Kaper J, Finlay B. Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake. The Embo Journal. 11: 3551-3560. DOI: 10.1002/j.1460-2075.1992.tb05438.x  0.603
1991 Leung KY, Finlay BB. Intracellular replication is essential for the virulence of Salmonella typhimurium Proceedings of the National Academy of Sciences of the United States of America. 88: 11470-11474. PMID 1763061 DOI: 10.1073/PNAS.88.24.11470  0.357
1990 Gahring LC, Heffron F, Finlay BB, Falkow S. Invasion and replication of Salmonella typhimurium in animal cells. Infection and Immunity. 58: 443-8. PMID 2404872  0.509
1988 Pasloske BL, Carpenter MR, Frost LS, Finlay BB, Paranchych W. The expression of Pseudomonas aeruginosa PAK pilin gene mutants in Escherichia coli. Molecular Microbiology. 2: 185-95. PMID 3132584 DOI: 10.1111/j.1365-2958.1988.tb00020.x  0.529
1986 Finlay BB, Frost LS, Paranchych W. Origin of transfer of IncF plasmids and nucleotide sequences of the type II oriT, traM, and traY alleles from ColB4-K98 and the type IV traY allele from R100-1. Journal of Bacteriology. 168: 132-9. PMID 3531163 DOI: 10.1128/jb.168.1.132-139.1986  0.445
1986 Finlay BB, Frost LS, Paranchych W. Nucleotide sequences of the R1-19 plasmid transfer genes traM, finP, traJ, and traY and the traYZ promoter. Journal of Bacteriology. 166: 368-74. PMID 3009392 DOI: 10.1128/jb.166.2.368-374.1986  0.457
1986 Finlay BB, Frost LS, Paranchych W. Nucleotide sequence of the tra YALE region from IncFV plasmid pED208. Journal of Bacteriology. 168: 990-8. PMID 2877970 DOI: 10.1128/jb.168.2.990-998.1986  0.482
1986 Finlay BB, Frost LS, Paranchych W, Willetts NS. Nucleotide sequences of five IncF plasmid finP alleles. Journal of Bacteriology. 167: 754-7. PMID 2426248 DOI: 10.1128/jb.167.2.754-757.1986  0.438
1986 Worobec EA, Frost LS, Pieroni P, Armstrong GD, Hodges RS, Parker JM, Finlay BB, Paranchych W. Location of the antigenic determinants of conjugative F-like pili Journal of Bacteriology. 167: 660-665. PMID 2426247 DOI: 10.1128/Jb.167.2.660-665.1986  0.419
1985 Frost LS, Finlay BB, Opgenorth A, Paranchych W, Lee JS. Characterization and sequence analysis of pilin from F-like plasmids. Journal of Bacteriology. 164: 1238-1247. DOI: 10.1128/jb.164.3.1238-1247.1985  0.423
1985 Finlay BB, Frost LS, Paranchych W, Parker JM, Hodges RS. Major antigenic determinants of F and ColB2 pili. Journal of Bacteriology. 163: 331-335. DOI: 10.1128/Jb.163.1.331-335.1985  0.424
1984 Finlay BB, Frost LS, Paranchych W. Localization, cloning, and sequence determination of the conjugative plasmid ColB2 pilin gene. Journal of Bacteriology. 160: 402-407. DOI: 10.1128/jb.160.1.402-407.1984  0.439
1983 Frost LS, Armstrong GD, Finlay BB, Edwards BF, Paranchych W. N-terminal amino acid sequencing of EDP208 conjugative pili Journal of Bacteriology. 153: 950-954. PMID 6130062  0.434
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