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Dehua Pei - Publications

Affiliations: 
Chemistry and Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
chemical biology, medicinal chemistry
Website:
http://chemistry.osu.edu/faculty/pei

191 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nubbemeyer B, Paul George AA, Kühl T, Pepanian A, Beck MS, Maghraby R, Shetab Boushehri M, Muehlhaupt M, Pfeil EM, Annala SK, Ammer H, Imhof D, Pei D. Targeting Gαi/s Proteins with Peptidyl Nucleotide Exchange Modulators. Acs Chemical Biology. PMID 35042325 DOI: 10.1021/acschembio.1c00929  0.669
2021 Buyanova M, Cai S, Cooper J, Rhodes C, Salim H, Sahni A, Upadhyaya P, Yang R, Sarkar A, Li N, Wang QE, Pei D. Discovery of a Bicyclic Peptidyl Pan-Ras Inhibitor. Journal of Medicinal Chemistry. PMID 34415745 DOI: 10.1021/acs.jmedchem.1c01130  0.56
2020 Dougherty PG, Karpurapu M, Koley A, Lukowski JK, Qian Z, Srinivas Nirujogi T, Rusu L, Chung S, Hummon AB, Li HW, Christman JW, Pei D. A Peptidyl Inhibitor that Blocks Calcineurin-NFAT Interaction and Prevents Acute Lung Injury. Journal of Medicinal Chemistry. PMID 33073986 DOI: 10.1021/acs.jmedchem.0c01236  0.693
2020 Wen J, Liao H, Stachowski K, Hempfling JP, Qian Z, Yuan C, Foster MP, Pei D. Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif. Bioorganic & Medicinal Chemistry. 28: 115711. PMID 33069067 DOI: 10.1016/J.Bmc.2020.115711  0.769
2020 Sahni A, Qian Z, Pei D. Cell-Penetrating Peptides Escape the Endosome by Inducing Vesicle Budding and Collapse. Acs Chemical Biology. PMID 32786250 DOI: 10.1021/Acschembio.0C00478  0.762
2019 Dougherty PG, Wen J, Pan X, Koley A, Ren JG, Sahni A, Basu R, Salim H, Appiah-Kubi G, Qian Z, Pei D. Enhancing the Cell-Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide. Journal of Medicinal Chemistry. PMID 31657556 DOI: 10.1021/Acs.Jmedchem.9B00456  0.787
2019 Salim H, Song J, Sahni A, Pei D. Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction. The Journal of Organic Chemistry. PMID 31609620 DOI: 10.1021/Acs.Joc.9B02367  0.483
2019 Pei D, Song J, Qian Z, Sahni A, Chen K. Cyclic Cell-Penetrating Peptides with Single Hydrophobic Groups. Chembiochem : a European Journal of Chemical Biology. PMID 31298779 DOI: 10.1002/Cbic.201900370  0.776
2019 Appiah Kubi G, Dougherty PG, Pei D. Designing Cell-Permeable Macrocyclic Peptides. Methods in Molecular Biology (Clifton, N.J.). 2001: 41-59. PMID 31134566 DOI: 10.1007/978-1-4939-9504-2_3  0.473
2019 Dougherty PG, Sahni A, Pei D. Understanding Cell Penetration of Cyclic Peptides. Chemical Reviews. PMID 31083977 DOI: 10.1021/Acs.Chemrev.9B00008  0.48
2019 Caldwell BJ, Zakharova E, Filsinger GT, Wannier TM, Hempfling JP, Chun-Der L, Pei D, Church GM, Bell CE. Crystal structure of the Red beta C-terminal domain in complex with lambda Exonuclease reveals an unexpected homology with lambda Orf and an interaction with Escherichia coli single stranded DNA binding protein. Nucleic Acids Research. 47: 1950-1963. DOI: 10.2210/Pdb6M9K/Pdb  0.362
2018 Pei D, Appiah Kubi G, Qian Z, Amiar S, Sahni A, Stahelin RV. Non-Peptidic Cell-Penetrating Motifs for Mitochondrion-Specific Cargo Delivery. Angewandte Chemie (International Ed. in English). PMID 30376611 DOI: 10.1002/Anie.201811940  0.739
2018 Rhodes CA, Dougherty PG, Cooper JK, Qian Z, Lindert S, Wang QE, Pei D. Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB kinase Interaction Directly from a Combinatorial Library. Journal of the American Chemical Society. PMID 30176143 DOI: 10.1021/Jacs.8B06738  0.782
2018 Karpurapu M, Lee YG, Qian Z, Wen J, Ballinger MN, Rusu L, Chung S, Deng J, Qian F, Reader BF, Nirujogi TS, Park GY, Pei D, Christman JW. Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis. Oncotarget. 9: 10606-10620. PMID 29535830 DOI: 10.18632/Oncotarget.24320  0.703
2017 Liao H, Pei D. Cell-permeable bicyclic peptidyl inhibitors against T-cell protein tyrosine phosphatase from a combinatorial library. Organic & Biomolecular Chemistry. PMID 29116277 DOI: 10.1039/C7Ob02562A  0.367
2017 Pei D, Chen K, Liao H. Targeting Ras with Macromolecules. Cold Spring Harbor Perspectives in Medicine. PMID 28778966 DOI: 10.1101/Cshperspect.A031476  0.319
2017 Bedewy W, Liao H, Abou-Taleb NA, Hammad SF, Nasr T, Pei D. Generation of a cell-permeable cycloheptapeptidyl inhibitor against the peptidyl-prolyl isomerase Pin1. Organic & Biomolecular Chemistry. PMID 28517007 DOI: 10.1039/C7Ob00430C  0.428
2017 Qian Z, Dougherty PG, Pei D. Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides. Current Opinion in Chemical Biology. 38: 80-86. PMID 28388463 DOI: 10.1016/J.Cbpa.2017.03.011  0.789
2017 Dougherty PG, Qian Z, Pei D. Macrocycles as protein-protein interaction inhibitors. The Biochemical Journal. 474: 1109-1125. PMID 28298556 DOI: 10.1042/Bcj20160619  0.758
2017 Dalbey RE, Pei D, Ekici ÖD. Signal Peptidase Enzymology and Substrate Specificity Profiling. Methods in Enzymology. 584: 35-57. PMID 28065271 DOI: 10.1016/Bs.Mie.2016.09.025  0.386
2016 Qian Z, Rhodes CA, McCroskey LC, Wen J, Appiah-Kubi G, Wang DJ, Guttridge DC, Pei D. Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization. Angewandte Chemie (International Ed. in English). PMID 28035784 DOI: 10.1002/Anie.201610888  0.763
2016 Sun H, Liang L, Li Y, Feng C, Li L, Zhang Y, He S, Pei D, Guo Y, Zheng H. Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch. Scientific Reports. 6: 30903. PMID 27481483 DOI: 10.1038/Srep30903  0.329
2016 Liu YF, Wang BY, Zhang WN, Huang JY, Li BS, Zhang M, Jiang L, Li JF, Wang MJ, Dai YJ, Zhang ZG, Wang Q, Kong J, Chen B, Zhu YM, ... ... Pei D, et al. Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia. Ebiomedicine. 8: 173-183. PMID 27428428 DOI: 10.1016/J.Ebiom.2016.04.038  0.534
2016 Zhang Y, Chen Y, Fu Y, Ying C, Feng Y, Huang Q, Wang C, Pei DS, Wang D. Monitoring tetracycline through a solid-state nanopore sensor. Scientific Reports. 6: 27959. PMID 27306259 DOI: 10.1038/srep27959  0.304
2016 Lin JD, Wu CZ, Pei D, Lian WC, Hsu CH, Hsieh CH, Chen YL. Identification of Impaired Second-Phase Insulin Secretion in Various Degrees of Glucose Tolerance in a Chinese Population. Metabolic Syndrome and Related Disorders. PMID 27303892 DOI: 10.1089/met.2015.0128  0.68
2016 Qian Z, Martyna A, Hard RL, Wang J, Appiah-Kubi G, Coss CC, Phelps M, Rossman JS, Pei D. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. PMID 27089101 DOI: 10.1021/Acs.Biochem.6B00226  0.812
2016 Trinh TB, Pei D. Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates. Methods in Molecular Biology (Clifton, N.J.). 1360: 169-81. PMID 26501910 DOI: 10.1007/978-1-4939-3073-9_13  0.631
2015 He S, Guo Y, Zhang Y, Li Y, Feng C, Li X, Lin L, Guo L, Wang H, Liu C, Zheng Y, Luo C, Liu Q, Wang F, Sun H, ... ... Pei D, et al. Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo. Cell Regeneration (London, England). 4: 12. PMID 26719791 DOI: 10.1186/S13619-015-0027-6  0.332
2015 Zhang YC, Du WQ, Zhang RY, Zheng JN, Pei DS. Jade-1: its structure, regulation and functions in the renal cancer. Current Molecular Medicine. PMID 26695694  0.323
2015 Trinh TB, Upadhyaya P, Qian Z, Pei D. Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides. Acs Combinatorial Science. PMID 26645887 DOI: 10.1021/Acscombsci.5B00164  0.827
2015 Ying Z, Chen K, Zheng L, Wu Y, Li L, Wang R, Long Q, Yang L, Guo J, Yao D, Li Y, Bao F, Xiang G, Liu J, Huang Q, ... Pei D, et al. Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming. Cell Metabolism. PMID 26549484 DOI: 10.1016/J.Cmet.2015.10.002  0.519
2015 Upadhyaya P, Bedewy W, Pei D. Direct Inhibitors of Ras-Effector Protein Interactions. Mini Reviews in Medicinal Chemistry. PMID 26423701 DOI: 10.2174/1389557515666151001141713  0.609
2015 Wu Y, Chen K, Liu X, Huang L, Zhao D, Li L, Gao M, Pei D, Wang C, Liu X. Srebp-1 interacts with c-Myc to enhance somatic cell reprogramming. Stem Cells (Dayton, Ohio). PMID 26388522 DOI: 10.1002/Stem.2209  0.332
2015 Jiang B, Pei D. A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1. Journal of Medicinal Chemistry. 58: 6306-12. PMID 26196061 DOI: 10.1021/Acs.Jmedchem.5B00411  0.381
2015 Ye W, Jiang Z, Li GX, Xiao Y, Lin S, Lai Y, Wang S, Li B, Jia B, Li Y, Huang ZL, Li J, Feng F, Li S, Yao H, ... ... Pei D, et al. Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments. Journal of Hematology & Oncology. 8: 59. PMID 26022250 DOI: 10.1186/S13045-015-0156-Y  0.307
2015 Qin L, Yao D, Zheng L, Liu WC, Liu Z, Lei M, Huang L, Xie X, Wang X, Chen Y, Yao X, Peng J, Gong H, Griffith JF, Huang Y, ... ... Pei D, et al. Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits. Biomaterials. 59: 125-43. PMID 25968462 DOI: 10.1016/J.Biomaterials.2015.04.038  0.311
2015 Upadhyaya P, Qian Z, Selner NG, Clippinger SR, Wu Z, Briesewitz R, Pei D. Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides. Angewandte Chemie (International Ed. in English). 54: 7602-6. PMID 25950772 DOI: 10.1002/Anie.201502763  0.798
2015 Lin JD, Hsu CH, Liang YJ, Lian WC, Hsieh CH, Wu CZ, Pei D, Chen YL. The estimation of first-phase insulin secretion by using components of the metabolic syndrome in a chinese population. International Journal of Endocrinology. 2015: 675245. PMID 25815010 DOI: 10.1155/2015/675245  0.679
2015 Qian Z, Xu X, Amacher JF, Madden DR, Cormet-Boyaka E, Pei D. Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity. Angewandte Chemie (International Ed. in English). 54: 5874-8. PMID 25785567 DOI: 10.1002/Anie.201411594  0.783
2015 Xiao Y, Wei X, Jiang Z, Wang X, Ye W, Liu X, Zhang M, Xu Y, Wu D, Lai L, Yao H, Liu Z, Cao S, Liu P, Xu B, ... Pei D, et al. Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells. Journal of Hematology & Oncology. 8: 7. PMID 25652910 DOI: 10.1186/S13045-014-0102-4  0.309
2015 Qian Z, Upadhyaya P, Pei D. Synthesis and screening of one-bead-one-compound cyclic peptide libraries. Methods in Molecular Biology (Clifton, N.J.). 1248: 39-53. PMID 25616324 DOI: 10.1007/978-1-4939-2020-4_3  0.827
2015 Qian Z, Dougherty PG, Pei D. Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore. Chemical Communications (Cambridge, England). 51: 2162-5. PMID 25554998 DOI: 10.1039/C4Cc09441G  0.748
2015 Suo Z, Chen L, Pei D, Jin X, Zhang H. A new nuclear DNA marker from ubiquitin ligase gene region for genetic diversity detection of walnut germplasm resources Biotechnology Reports. 5: 40-45. DOI: 10.1016/j.btre.2014.11.003  0.385
2014 Upadhyaya P, Qian Z, Habir NA, Pei D. Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library. Tetrahedron. 70: 7714-7720. PMID 25284901 DOI: 10.1016/J.Tet.2014.05.113  0.811
2014 Qian Z, Dougherty PG, Liu T, Oottikkal S, Hogan PG, Hadad CM, Pei D. Structure-based optimization of a peptidyl inhibitor against calcineurin-nuclear factor of activated T cell (NFAT) interaction. Journal of Medicinal Chemistry. 57: 7792-7. PMID 25162754 DOI: 10.1021/Jm500743T  0.779
2014 Lian W, Jiang B, Qian Z, Pei D. Cell-permeable bicyclic peptide inhibitors against intracellular proteins. Journal of the American Chemical Society. 136: 9830-3. PMID 24972263 DOI: 10.1021/Ja503710N  0.832
2014 Liu P, Zhang Y, Chen S, Cai J, Pei D. Application of iPS cells in dental bioengineering and beyond. Stem Cell Reviews. 10: 663-70. PMID 24917330 DOI: 10.1007/S12015-014-9531-2  0.31
2014 Qian Z, LaRochelle JR, Jiang B, Lian W, Hard RL, Selner NG, Luechapanichkul R, Barrios AM, Pei D. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery. Biochemistry. 53: 4034-46. PMID 24896852 DOI: 10.1021/Bi5004102  0.766
2014 Lin JD, Hseih CH, Liu CC, Lian WC, Wu CZ, Hsu CH, Pei D, Hsia TL, Chen YL. Estimation of the disposition index based on components of metabolic syndrome. Endocrine Journal. 61: 789-96. PMID 24871963 DOI: 10.1507/endocrj.EJ13-0510  0.683
2014 Selner NG, Luechapanichkul R, Chen X, Neel BG, Zhang ZY, Knapp S, Bell CE, Pei D. Diverse levels of sequence selectivity and catalytic efficiency of protein-tyrosine phosphatases. Biochemistry. 53: 397-412. PMID 24359314 DOI: 10.1021/Bi401223R  0.803
2014 Liu H, Hsu CH, Lin JD, Hsieh CH, Lian WC, Wu CZ, Pei D, Chen YL. Predicting metabolic syndrome by using hematogram models in elderly women. Platelets. 25: 97-101. PMID 23534910 DOI: 10.3109/09537104.2013.780017  0.687
2013 Cai J, Zhang Y, Liu P, Chen S, Wu X, Sun Y, Li A, Huang K, Luo R, Wang L, Liu Y, Zhou T, Wei S, Pan G, Pei D. Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells. Cell Regeneration (London, England). 2: 6. PMID 25408878 DOI: 10.1186/2045-9769-2-6  0.305
2013 Lian WC, Lin JD, Hsia TL, Hsu CH, Wu CZ, Hsieh CH, Pei D, Chen YL. Metabolic syndrome in normoglycaemic elderly men. International Journal of Clinical Practice. 67: 964-70. PMID 24073972 DOI: 10.1111/ijcp.12166  0.669
2013 Lian W, Upadhyaya P, Rhodes CA, Liu Y, Pei D. Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonist. Journal of the American Chemical Society. 135: 11990-5. PMID 23865589 DOI: 10.1021/Ja405106U  0.826
2013 Trinh TB, Xiao Q, Pei D. Profiling the substrate specificity of protein kinases by on-bead screening of peptide libraries. Biochemistry. 52: 5645-55. PMID 23848432 DOI: 10.1021/Bi4008947  0.64
2013 Lian WC, Lin JD, Chang JB, Hsu CH, Pei C, Wu CZ, Hsieh CH, Pei D, Chen YL. Evaluation of second phase insulin secretion with simple surrogates derived from the mixed meal tolerance test in patients with type 2 diabetes. Endocrine Journal. 60: 1077-84. PMID 23811986 DOI: 10.1507/endocrj.EJ13-0042  0.684
2013 Xiao Q, Luechapanichkul R, Zhai Y, Pei D. Specificity profiling of protein phosphatases toward phosphoseryl and phosphothreonyl peptides. Journal of the American Chemical Society. 135: 9760-7. PMID 23758517 DOI: 10.1021/Ja401692T  0.82
2013 Wu X, Upadhyaya P, Villalona-Calero MA, Briesewitz R, Pei D. Inhibition of Ras-Effector Interaction by Cyclic Peptides. Medchemcomm. 4: 378-382. PMID 23585920 DOI: 10.1039/C2Md20329D  0.675
2013 Dai J, Pei D, Wang B, Kuang Y, Ren L, Cao K, Zuo B, Shao J, Li S, Jiang Z, Li H, Li M. A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and Staphylococcus aureus. Virology Journal. 10: 40. PMID 23369570 DOI: 10.1186/1743-422X-10-40  0.686
2013 Luechapanichkul R, Chen X, Taha HA, Vyas S, Guan X, Freitas MA, Hadad CM, Pei D. Specificity profiling of dual specificity phosphatase vaccinia VH1-related (VHR) reveals two distinct substrate binding modes. The Journal of Biological Chemistry. 288: 6498-510. PMID 23322772 DOI: 10.1074/Jbc.M112.449611  0.816
2013 Zhao B, Tan PH, Li SS, Pei D. Systematic characterization of the specificity of the SH2 domains of cytoplasmic tyrosine kinases. Journal of Proteomics. 81: 56-69. PMID 23313216 DOI: 10.1016/J.Jprot.2012.12.021  0.618
2013 Thakkar A, Trinh TB, Pei D. Global analysis of peptide cyclization efficiency. Acs Combinatorial Science. 15: 120-9. PMID 23265659 DOI: 10.1021/Co300136J  0.74
2013 Fan N, Chen J, Shang Z, Dou H, Ji G, Zou Q, Wu L, He L, Wang F, Liu K, Liu N, Han J, Zhou Q, Pan D, Yang D, ... ... Pei D, et al. Piglets cloned from induced pluripotent stem cells. Cell Research. 23: 162-6. PMID 23247628 DOI: 10.1038/Cr.2012.176  0.354
2013 Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, Liang H, Chen Y, Chen J, Wu Y, Guo L, Zhu J, Zhao X, Peng T, Zhang Y, ... Pei D, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nature Genetics. 45: 34-42. PMID 23202127 DOI: 10.1038/Ng.2491  0.497
2013 Qian Z, Liu T, Liu YY, Briesewitz R, Barrios AM, Jhiang SM, Pei D. Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs. Acs Chemical Biology. 8: 423-31. PMID 23130658 DOI: 10.1021/Cb3005275  0.808
2012 Kunys AR, Lian W, Pei D. Specificity profiling of protein-binding domains using one-bead-one-compound Peptide libraries. Current Protocols in Chemical Biology. 4: 331-55. PMID 23788558 DOI: 10.1002/9780470559277.Ch120125  0.787
2012 Dai J, Pei D, Wang B, Kuang Y, Ren L, Cao K, Wang H, Zuo B, Shao J, Li S, Li H, Li M. Molecular adjuvant Ag85A enhances protection against influenza A virus in mice following DNA vaccination. Viruses. 4: 3606-24. PMID 23223215 DOI: 10.3390/v4123606  0.685
2012 Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, Wang Y, Zhang Y, Zhuang Q, Li Y, Bao X, Tse HF, Grillari J, Grillari-Voglauer R, Pei D, et al. Generation of human induced pluripotent stem cells from urine samples. Nature Protocols. 7: 2080-9. PMID 23138349 DOI: 10.1038/Nprot.2012.115  0.314
2012 Wang Z, Pei D, Zhang Y, Wang C, Sun J. A facile one-pot process for the formation of hindered tertiary amines. Molecules (Basel, Switzerland). 17: 5151-63. PMID 22555302 DOI: 10.3390/Molecules17055151  0.33
2012 Pei D, Zhang Y, Zheng J. Regulation of p53: a collaboration between Mdm2 and Mdmx. Oncotarget. 3: 228-35. PMID 22410433 DOI: 10.18632/Oncotarget.443  0.347
2012 Qi D, Liu H, Niu J, Fan X, Wen X, Du Y, Mou J, Pei D, Liu Z, Zong Z, Wei X, Song Y. Heat shock protein 72 inhibits c-Jun N-terminal kinase 3 signaling pathway via Akt1 during cerebral ischemia. Journal of the Neurological Sciences. 317: 123-9. PMID 22386689 DOI: 10.1016/j.jns.2012.02.011  0.335
2012 Liu Z, Lv C, Zhao W, Song Y, Pei D, Xu T. NR2B-containing NMDA receptors expression and their relationship to apoptosis in hippocampus of Alzheimer's disease-like rats. Neurochemical Research. 37: 1420-7. PMID 22359056 DOI: 10.1007/s11064-012-0726-0  0.3
2012 Pei D, Dai J, Kuang Y, Wang H, Ren L, Shao J, Zuo B, Li S, Jiang Z, Li M. Effect of influenza A virus non-structural protein 1(NS1) on a mouse model of diabetes mellitus induced by Streptozotocin. Biochemical and Biophysical Research Communications. 419: 120-5. PMID 22330802 DOI: 10.1016/j.bbrc.2012.01.146  0.701
2012 Guo H, Tian R, Zhu J, Zhou H, Pei D, Wang X. Combined cadmium and elevated ozone affect concentrations of cadmium and antioxidant systems in wheat under fully open-air conditions. Journal of Hazardous Materials. 209: 27-33. PMID 22285914 DOI: 10.1016/j.jhazmat.2011.12.041  0.323
2012 Dewan V, Liu T, Chen KM, Qian Z, Xiao Y, Kleiman L, Mahasenan KV, Li C, Matsuo H, Pei D, Musier-Forsyth K. Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction. Acs Chemical Biology. 7: 761-9. PMID 22276994 DOI: 10.1021/Cb200450W  0.783
2012 Song YJ, Zong ZM, Liu HZ, Mukasa R, Pei DS, Mou J, Wen XR, Liu ZA, Wei XY. Heme oxygenase-1 regulates the JNK signaling pathway through the MLK3-MKK7-JNK3 signaling module in brain ischemia injury. Brain Research. 1429: 1-8. PMID 22088822 DOI: 10.1016/j.brainres.2011.10.021  0.33
2012 Liu Z, Xu J, Shen X, Lv C, Xu T, Pei D. CaMKII antisense oligodeoxynucleotides protect against ischemia-induced neuronal death in the rat hippocampus. Journal of the Neurological Sciences. 314: 104-10. PMID 22036300 DOI: 10.1016/j.jns.2011.10.012  0.35
2012 Li W, Wang X, Fan W, Zhao P, Chan YC, Chen S, Zhang S, Guo X, Zhang Y, Li Y, Cai J, Qin D, Li X, Yang J, Peng T, ... ... Pei D, et al. Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes. Human Molecular Genetics. 21: 32-45. PMID 21949351 DOI: 10.1093/Hmg/Ddr435  0.318
2011 Malladi VLA, Sobczak AJ, Meyer TM, Pei D, Wnuk SF. Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring Bioorganic and Medicinal Chemistry. 19: 5507-5519. PMID 21855358 DOI: 10.1016/J.Bmc.2011.07.043  0.336
2011 Liu T, Qian Z, Xiao Q, Pei D. High-throughput screening of one-bead-one-compound libraries: identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction. Acs Combinatorial Science. 13: 537-46. PMID 21848276 DOI: 10.1021/Co200101W  0.792
2011 Zhang Y, Zhang J, Yuan C, Hard RL, Park IH, Li C, Bell C, Pei D. Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry. 50: 7637-46. PMID 21800896 DOI: 10.1021/Bi200439V  0.75
2011 Guo H, Zhu J, Zhou H, Sun Y, Yin Y, Pei D, Ji R, Wu J, Wang X. Elevated CO2 levels affects the concentrations of copper and cadmium in crops grown in soil contaminated with heavy metals under fully open-air field conditions. Environmental Science & Technology. 45: 6997-7003. PMID 21770376 DOI: 10.1021/Es2001584  0.32
2011 Wu X, Wang L, Han Y, Regan N, Li PK, Villalona MA, Hu X, Briesewitz R, Pei D. Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library. Acs Combinatorial Science. 13: 486-95. PMID 21766878 DOI: 10.1021/Co200057N  0.37
2011 Wang Q, Xu X, Li J, Liu J, Gu H, Zhang R, Chen J, Kuang Y, Fei J, Jiang C, Wang P, Pei D, Ding S, Xie X. Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells. Cell Research. 21: 1424-35. PMID 21727907 DOI: 10.1038/Cr.2011.108  0.485
2011 Ren L, Chen X, Luechapanichkul R, Selner NG, Meyer TM, Wavreille AS, Chan R, Iorio C, Zhou X, Neel BG, Pei D. Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2. Biochemistry. 50: 2339-56. PMID 21291263 DOI: 10.1021/Bi1014453  0.8
2011 Plummer P, Zhu J, Akiba M, Pei D, Zhang Q. Identification of a key amino acid of LuxS involved in AI-2 production in Campylobacter jejuni. Plos One. 6: e15876. PMID 21264316 DOI: 10.1371/Journal.Pone.0015876  0.488
2011 Shepherd TR, Hard RL, Murray AM, Pei D, Fuentes EJ. Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domains. Biochemistry. 50: 1296-308. PMID 21192692 DOI: 10.1021/Bi1013613  0.665
2011 Zhang Y, Zhang J, Yuan C, Hard RL, Park I, Li C, Bell C, Pei D. Correction to Simultaneous Binding of Two Peptidyl Ligands by a Src Homology 2 Domain Biochemistry. 50: 8519-8519. DOI: 10.1021/Bi201369S  0.657
2010 Hard RL, Liu J, Shen J, Zhou P, Pei D. HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins. Biochemistry. 49: 10737-46. PMID 21090589 DOI: 10.1021/Bi101014S  0.686
2010 Yang J, Cai J, Zhang Y, Wang X, Li W, Xu J, Li F, Guo X, Deng K, Zhong M, Chen Y, Lai L, Pei D, Esteban MA. Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome. The Journal of Biological Chemistry. 285: 40303-11. PMID 20956530 DOI: 10.1074/Jbc.M110.183392  0.305
2010 Xu J, Liu ZA, Pei DS, Xu TJ. Calcium/calmodulin-dependent kinase II facilitated GluR6 subunit serine phosphorylation through GluR6-PSD95-CaMKII signaling module assembly in cerebral ischemia injury. Brain Research. 1366: 197-203. PMID 20888327 DOI: 10.1016/j.brainres.2010.09.087  0.342
2010 Chen X, Ren L, Kim S, Carpino N, Daniel JL, Kunapuli SP, Tsygankov AY, Pei D. Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate. The Journal of Biological Chemistry. 285: 31268-76. PMID 20670933 DOI: 10.1074/Jbc.M110.114181  0.813
2010 Xiao Q, Zhang F, Nacev BA, Liu JO, Pei D. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases. Biochemistry. 49: 5588-99. PMID 20521764 DOI: 10.1021/Bi1005464  0.543
2010 Liu T, Liu Y, Kao HY, Pei D. Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1. Journal of Medicinal Chemistry. 53: 2494-501. PMID 20180533 DOI: 10.1021/Jm901778V  0.583
2010 Li C, Xu B, Wang WW, Yu XJ, Zhu J, Yu HM, Han D, Pei DS, Zhang GY. Coactivation of GABA receptors inhibits the JNK3 apoptotic pathway via disassembly of GluR6-PSD-95-MLK3 signaling module in KA-induced seizure. Epilepsia. 51: 391-403. PMID 19694794 DOI: 10.1111/j.1528-1167.2009.02270.x  0.369
2009 Zhang Y, Wavreille AS, Kunys AR, Pei D. The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics. Biochemistry. 48: 11075-83. PMID 19839650 DOI: 10.1021/Bi9012462  0.551
2009 Wnuk SF, Robert J, Sobczak AJ, Meyers BP, Malladi VL, Zhu J, Gopishetty B, Pei D. Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position. Bioorganic & Medicinal Chemistry. 17: 6699-706. PMID 19682914 DOI: 10.1016/J.Bmc.2009.07.057  0.507
2009 Hu SQ, Zhu J, Pei DS, Zong YY, Yan JZ, Hou XY, Zhang GY. Overexpression of the PDZ1 domain of PSD-95 diminishes ischemic brain injury via inhibition of the GluR6.PSD-95.MLK3 pathway. Journal of Neuroscience Research. 87: 3626-38. PMID 19610093 DOI: 10.1002/jnr.22163  0.436
2009 Ekici OD, Zhu J, Wah Chung IY, Paetzel M, Dalbey RE, Pei D. Profiling the substrate specificity of viral protease VP4 by a FRET-based peptide library approach. Biochemistry. 48: 5753-9. PMID 19435306 DOI: 10.1021/Bi900461E  0.619
2009 Chen X, Tan PH, Zhang Y, Pei D. On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density. Journal of Combinatorial Chemistry. 11: 604-11. PMID 19397369 DOI: 10.1021/Cc9000168  0.811
2009 Wu CZ, Lin JD, Li JC, Kuo SW, Hsieh CH, Lian WC, Lee CH, Wan HL, Hung YJ, Pei D. Association between white blood cell count and components of metabolic syndrome. Pediatrics International : Official Journal of the Japan Pediatric Society. 51: 14-8. PMID 19371272 DOI: 10.1111/j.1442-200X.2008.02658.x  0.673
2009 Thakkar A, Cohen AS, Connolly MD, Zuckermann RN, Pei D. High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry. Journal of Combinatorial Chemistry. 11: 294-302. PMID 19154119 DOI: 10.1021/Cc8001734  0.728
2009 Gopishetty B, Zhu J, Rajan R, Sobczak AJ, Wnuk SF, Bell CE, Pei D. Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues. Journal of the American Chemical Society. 131: 1243-50. PMID 19099445 DOI: 10.1021/Ja808206W  0.491
2009 Liu T, Joo SH, Voorhees JL, Brooks CL, Pei D. Synthesis and screening of a cyclic peptide library: discovery of small-molecule ligands against human prolactin receptor. Bioorganic & Medicinal Chemistry. 17: 1026-33. PMID 18234500 DOI: 10.1016/J.Bmc.2008.01.015  0.697
2008 Qin D, Gan Y, Shao K, Wang H, Li W, Wang T, He W, Xu J, Zhang Y, Kou Z, Zeng L, Sheng G, Esteban MA, Gao S, Pei D. Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors. The Journal of Biological Chemistry. 283: 33730-5. PMID 18826945 DOI: 10.1074/Jbc.M806788200  0.334
2008 Gopishetty B, Ren L, Waller TM, Wavreille AS, Lopez M, Thakkar A, Zhu J, Pei D. Synthesis of 3,5-difluorotyrosine-containing peptides: application in substrate profiling of protein tyrosine phosphatases. Organic Letters. 10: 4605-8. PMID 18798640 DOI: 10.1021/Ol801868A  0.833
2008 Nguyen KT, Pei D. High-throughput screening of peptide deformylase inhibitors. Methods in Molecular Medicine. 142: 117-30. PMID 18437310 DOI: 10.1007/978-1-59745-246-5_10  0.629
2008 Wnuk SF, Lalama J, Garmendia CA, Robert J, Zhu J, Pei D. S-Ribosylhomocysteine analogues with the carbon-5 and sulfur atoms replaced by a vinyl or (fluoro)vinyl unit. Bioorganic & Medicinal Chemistry. 16: 5090-102. PMID 18375129 DOI: 10.1016/J.Bmc.2008.03.028  0.454
2008 Zhang Y, Zhou S, Wavreille AS, DeWille J, Pei D. Cyclic peptidyl inhibitors of Grb2 and tensin SH2 domains identified from combinatorial libraries. Journal of Combinatorial Chemistry. 10: 247-55. PMID 18257540 DOI: 10.1021/Cc700185G  0.588
2008 Joo SH, Pei D. Synthesis and screening of support-bound combinatorial peptide libraries with free C-termini: determination of the sequence specificity of PDZ domains. Biochemistry. 47: 3061-72. PMID 18232644 DOI: 10.1021/Bi7023628  0.678
2008 Zhu J, Pei D. A LuxP-based fluorescent sensor for bacterial autoinducer II. Acs Chemical Biology. 3: 110-9. PMID 18215018 DOI: 10.1021/Cb7002048  0.458
2008 Shen G, Zhu J, Simpson AM, Pei D. Design and synthesis of macrocyclic peptidyl hydroxamates as peptide deformylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3060-3. PMID 18093832 DOI: 10.1016/J.Bmcl.2007.12.011  0.583
2007 Nguyen KT, Wu JC, Boylan JA, Gherardini FC, Pei D. Zinc is the metal cofactor of Borrelia burgdorferi peptide deformylase. Archives of Biochemistry and Biophysics. 468: 217-25. PMID 17977509 DOI: 10.1016/J.Abb.2007.09.023  0.588
2007 Lin JD, Wan HL, Li JC, Wu CZ, Kuo SW, Hsieh CH, Lian WC, Lee CH, Kao MT, Pei D. Impaired glucose tolerance and impaired fasting glucose share similar underlying pathophysiologies. The Tohoku Journal of Experimental Medicine. 212: 349-57. PMID 17660700 DOI: JST.JSTAGE/tjem/212.349  0.679
2007 Pei D, Wavreille AS. Reverse interactomics: decoding protein-protein interactions with combinatorial peptide libraries. Molecular Biosystems. 3: 536-41. PMID 17639128 DOI: 10.1039/B706041F  0.434
2007 Xiao Q, Pei D. High-throughput synthesis and screening of cyclic peptide antibiotics. Journal of Medicinal Chemistry. 50: 3132-7. PMID 17547386 DOI: 10.1021/Jm070282E  0.432
2007 Wavreille AS, Garaud M, Zhang Y, Pei D. Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries. Methods (San Diego, Calif.). 42: 207-19. PMID 17532507 DOI: 10.1016/J.Ymeth.2007.02.010  0.591
2007 Garaud M, Pei D. Substrate profiling of protein tyrosine phosphatase PTP1B by screening a combinatorial peptide library. Journal of the American Chemical Society. 129: 5366-7. PMID 17417856 DOI: 10.1021/Ja071275I  0.45
2007 Rajamani S, Zhu J, Pei D, Sayre R. A LuxP-FRET-based reporter for the detection and quantification of AI-2 bacterial quorum-sensing signal compounds. Biochemistry. 46: 3990-7. PMID 17352493 DOI: 10.1021/Bi602479E  0.474
2007 Wavreille AS, Pei D. A chemical approach to the identification of tensin-binding proteins. Acs Chemical Biology. 2: 109-18. PMID 17256997 DOI: 10.1021/Cb600433G  0.472
2007 Ekici OD, Karla A, Paetzel M, Lively MO, Pei D, Dalbey RE. Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library. The Journal of Biological Chemistry. 282: 417-25. PMID 17077081 DOI: 10.1074/Jbc.M608779200  0.4
2006 Sweeney MC, Wang X, Park J, Liu Y, Pei D. Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library. Biochemistry. 45: 14740-8. PMID 17144666 DOI: 10.1021/Bi061782X  0.829
2006 Pei D, Wang Z, Wei S, Zhang Y, Sun J. S-chiral sulfinamides as highly enantioselective organocatalysts. Organic Letters. 8: 5913-5. PMID 17134304 DOI: 10.1021/Ol062633+  0.307
2006 Zhu J, Knottenbelt S, Kirk ML, Pei D. Catalytic mechanism of S-ribosylhomocysteinase: ionization state of active-site residues. Biochemistry. 45: 12195-203. PMID 17014073 DOI: 10.1021/Bi061434V  0.487
2006 Joo SH, Xiao Q, Ling Y, Gopishetty B, Pei D. High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry. Journal of the American Chemical Society. 128: 13000-9. PMID 17002397 DOI: 10.1021/Ja063722K  0.725
2006 Thakkar A, Wavreille AS, Pei D. Traceless capping agent for peptide sequencing by partial edman degradation and mass spectrometry. Analytical Chemistry. 78: 5935-9. PMID 16906744 DOI: 10.1021/Ac0607414  0.645
2006 Imhof D, Wavreille AS, May A, Zacharias M, Tridandapani S, Pei D. Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position. The Journal of Biological Chemistry. 281: 20271-82. PMID 16702225 DOI: 10.1074/Jbc.M601047200  0.685
2006 Shen G, Rajan R, Zhu J, Bell CE, Pei D. Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase. Journal of Medicinal Chemistry. 49: 3003-11. PMID 16686542 DOI: 10.1021/Jm060047G  0.522
2006 Pei D, Hsiao CF, Hung YJ, Hsieh CH, Fang SC, Lian WC, Hsu WL, Fu CC, Chen HD, Kuo SW. The insulin sensitivity, glucose sensitivity, and acute insulin response to glucose load in adolescent type 2 diabetes in Taiwanese. Diabetes/Metabolism Research and Reviews. 22: 26-33. PMID 15880384 DOI: 10.1002/dmrr.522  0.674
2006 Shen G, Rajan R, Zhu J, Bell CE, Pei D. Design and Synthesis of Substrate Analogue Inhibitors of S-Ribosylhomocysteinase (LuxS) Journal of Medicinal Chemistry. 49: 3003-3011. DOI: 10.2210/Pdb2Fqt/Pdb  0.477
2005 Lee CH, Kuo SW, Hung YJ, Hsieh CH, He CT, Yang TC, Lian WC, Chyi-Fan S, Pei D. The effect of testosterone supplement on insulin sensitivity, glucose effectiveness, and acute insulin response after glucose load in male type 2 diabetics. Endocrine Research. 31: 139-48. PMID 16353672  0.681
2005 Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D. Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains. Biochemistry. 44: 14932-47. PMID 16274240 DOI: 10.1021/Bi051408H  0.831
2005 Nguyen KT, Pei D. Purification and characterization of enzymes involved in the degradation of chemotactic N-formyl peptides. Biochemistry. 44: 8514-22. PMID 15938642 DOI: 10.1021/Bi050191O  0.613
2005 Hsieh CH, Kuo SW, Hung YJ, Shen DC, Ho CT, Lian WC, Lee CH, Fan SC, Pei D. Metabolic characteristics in individuals with impaired glucose homeostasis. International Journal of Clinical Practice. 59: 639-44. PMID 15924590 DOI: 10.1111/j.1742-1241.2005.00494.x  0.68
2005 Qin BM, Chen X, Zhu JD, Pei DQ. Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy. Cell Research. 15: 212-7. PMID 15780185 DOI: 10.1038/sj.cr.7290289  0.355
2005 Rajan R, Zhu J, Hu X, Pei D, Bell CE. Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate. Biochemistry. 44: 3745-53. PMID 15751951 DOI: 10.1021/Bi0477384  0.481
2004 Hsieh CH, Kuo SW, Pei D, Hung YJ, Chyi-Fan S, Wu LI, He CT, Yang TC, Lian WC, Chien-Hsing L. Thyrotoxic periodic paralysis: an overview. Annals of Saudi Medicine. 24: 418-22. PMID 15646156  0.665
2004 Park J, Pei D. trans-Beta-nitrostyrene derivatives as slow-binding inhibitors of protein tyrosine phosphatases. Biochemistry. 43: 15014-21. PMID 15554709 DOI: 10.1021/Bi0486233  0.782
2004 Pei D, Hung YJ, Chen HD, Hsiao CF, Fu CC, Yang TC, Lian WC, Fang SC, Hsu WL, Kuo SW. The insulin sensitivity, glucose effectiveness and acute insulin response to glucose load of non-obese adolescent type 2 diabetes. Diabetes Research and Clinical Practice. 66: 253-61. PMID 15536022 DOI: 10.1016/j.diabres.2004.04.006  0.682
2004 Zhu J, Dhimitruka I, Pei D. 5-(2-Aminoethyl)dithio-2-nitrobenzoate as a more base-stable alternative to Ellman's reagent. Organic Letters. 6: 3809-12. PMID 15469355 DOI: 10.1021/Ol048404+  0.445
2004 Pei D, Zhu J. Mechanism of action of S-ribosylhomocysteinase (LuxS). Current Opinion in Chemical Biology. 8: 492-7. PMID 15450491 DOI: 10.1016/J.Cbpa.2004.08.003  0.463
2004 Hu X, Nguyen KT, Jiang VC, Lofland D, Moser HE, Pei D. Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. Journal of Medicinal Chemistry. 47: 4941-9. PMID 15369398 DOI: 10.1021/Jm049592C  0.654
2004 Zhu J, Patel R, Pei D. Catalytic mechanism of S-ribosylhomocysteinase (LuxS): stereochemical course and kinetic isotope effect of proton transfer reactions. Biochemistry. 43: 10166-72. PMID 15287744 DOI: 10.1021/Bi0491088  0.467
2004 He CT, Hsieh AT, Pei D, Hung YJ, Wu LY, Yang TC, Lian WC, Huang WS, Kuo SW. Comparison of single daily dose of methimazole and propylthiouracil in the treatment of Graves' hyperthyroidism. Clinical Endocrinology. 60: 676-81. PMID 15163329 DOI: 10.1111/j.1365-2265.2004.02032.x  0.664
2004 Nguyen KT, Hu X, Pei D. Slow-binding inhibition of peptide deformylase by cyclic peptidomimetics as revealed by a new spectrophotometric assay. Bioorganic Chemistry. 32: 178-91. PMID 15110195 DOI: 10.1016/J.Bioorg.2004.01.001  0.664
2004 Robien MA, Nguyen KT, Kumar A, Hirsh I, Turley S, Pei D, Hol WG. An improved crystal form of Plasmodium falciparum peptide deformylase. Protein Science : a Publication of the Protein Society. 13: 1155-63. PMID 15010544 DOI: 10.1110/Ps.03456404  0.628
2004 Park J, Fu H, Pei D. Peptidyl aldehydes as slow-binding inhibitors of dual-specificity phosphatases. Bioorganic & Medicinal Chemistry Letters. 14: 685-7. PMID 14741269 DOI: 10.1016/J.Bmcl.2003.11.027  0.768
2004 Xian M, Fatima Z, Zhang W, Fang J, Li H, Pei D, Loo J, Stevenson T, Wang PG. Identification of alpha-galactosyl epitope mimetics through rapid generation and screening of C-linked glycopeptide library. Journal of Combinatorial Chemistry. 6: 126-34. PMID 14714996 DOI: 10.1021/Cc030042U  0.383
2004 Hu X, Zhu J, Srivathsan S, Pei D. Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 77-9. PMID 14684302 DOI: 10.1016/J.Bmcl.2003.10.031  0.496
2003 Zhu J, Hu X, Dizin E, Pei D. Catalytic mechanism of S-ribosylhomocysteinase (LuxS): direct observation of ketone intermediates by 13C NMR spectroscopy. Journal of the American Chemical Society. 125: 13379-81. PMID 14583032 DOI: 10.1021/Ja0369663  0.484
2003 Hu X, Nguyen KT, Verlinde CL, Hol WG, Pei D. Structure-based design of a macrocyclic inhibitor for peptide deformylase. Journal of Medicinal Chemistry. 46: 3771-4. PMID 12930137 DOI: 10.1021/Jm034113F  0.638
2003 Nguyen KT, Hu X, Colton C, Chakrabarti R, Zhu MX, Pei D. Characterization of a human peptide deformylase: implications for antibacterial drug design. Biochemistry. 42: 9952-8. PMID 12924944 DOI: 10.1021/Bi0346446  0.664
2003 Sweeney MC, Pei D. An improved method for rapid sequencing of support-bound peptides by partial edman degradation and mass spectrometry. Journal of Combinatorial Chemistry. 5: 218-22. PMID 12739936 DOI: 10.1021/Cc020113+  0.678
2003 Park J, Fu H, Pei D. Peptidyl aldehydes as reversible covalent inhibitors of SRC homology 2 domains. Biochemistry. 42: 5159-67. PMID 12718560 DOI: 10.1021/Bi034076U  0.79
2003 Zhu J, Dizin E, Hu X, Wavreille AS, Park J, Pei D. S-Ribosylhomocysteinase (LuxS) is a mononuclear iron protein. Biochemistry. 42: 4717-26. PMID 12705835 DOI: 10.1021/Bi034289J  0.773
2002 Arabaci G, Yi T, Fu H, Porter ME, Beebe KD, Pei D. alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship. Bioorganic & Medicinal Chemistry Letters. 12: 3047-50. PMID 12372498 DOI: 10.1016/S0960-894X(02)00681-9  0.783
2002 Fu H, Park J, Pei D. Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases. Biochemistry. 41: 10700-9. PMID 12186556 DOI: 10.1021/Bi0258748  0.779
2002 Deng H, Callender R, Zhu J, Nguyen KT, Pei D. Determination of the ionization state and catalytic function of Glu-133 in peptide deformylase by difference FTIR spectroscopy. Biochemistry. 41: 10563-9. PMID 12173943 DOI: 10.1021/Bi026137E  0.674
2002 Kumar A, Nguyen KT, Srivathsan S, Ornstein B, Turley S, Hirsh I, Pei D, Hol WG. Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design. Structure (London, England : 1993). 10: 357-67. PMID 12005434 DOI: 10.1016/S0969-2126(02)00719-0  0.66
2002 Wang P, Fu H, Snavley DF, Freitas MA, Pei D. Screening combinatorial libraries by mass spectrometry. 2. Identification of optimal substrates of protein tyrosine phosphatase SHP-1. Biochemistry. 41: 6202-10. PMID 11994017 DOI: 10.1021/Bi025591F  0.492
2001 Bracchi-Ricard V, Nguyen KT, Zhou Y, Rajagopalan PT, Chakrabarti D, Pei D. Characterization of an eukaryotic peptide deformylase from Plasmodium falciparum. Archives of Biochemistry and Biophysics. 396: 162-70. PMID 11747293 DOI: 10.1006/Abbi.2001.2631  0.655
2001 Wang P, Snavley DF, Freitas MA, Pei D. Screening combinatorial libraries for optimal enzyme substrates by mass spectrometry Rapid Communications in Mass Spectrometry. 15: 1166-1171. PMID 11445898 DOI: 10.1002/Rcm.360  0.447
2001 Wang P, Arabaci G, Pei D. Rapid sequencing of library-derived peptides by partial edman degradation and mass spectrometry. Journal of Combinatorial Chemistry. 3: 251-4. PMID 11350247 DOI: 10.1021/Cc000102L  0.786
2001 Pei D. Peptide deformylase: A target for novel antibiotics? Expert Opinion On Therapeutic Targets. 5: 23-24. DOI: 10.1517/14728222.5.1.23  0.387
2000 Wei Y, Yi T, Huntington KM, Chaudhury C, Pei D. Identification of a potent peptide deformylase inhibitor from a rationally designed combinatorial library Journal of Combinatorial Chemistry. 2: 650-657. PMID 11126293 DOI: 10.1021/Cc000036N  0.814
2000 Liao H, Yuan C, Su MI, Yongkiettrakul S, Qin D, Li H, Byeon IJ, Pei D, Tsai MD. Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9. Journal of Molecular Biology. 304: 941-51. PMID 11124038 DOI: 10.1006/Jmbi.2000.4291  0.471
2000 Beebe KD, Wang P, Arabaci G, Pei D. Determination of the binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library. Biochemistry. 39: 13251-60. PMID 11052678 DOI: 10.1021/Bi0014397  0.832
2000 Wang P, Byeon IJ, Liao H, Beebe KD, Yongkiettrakul S, Pei D, Tsai MD. II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. Journal of Molecular Biology. 302: 927-40. PMID 10993733 DOI: 10.1006/Jmbi.2000.4095  0.796
2000 Wei Y, Pei D. Activation of antibacterial prodrugs by peptide deformylase Bioorganic and Medicinal Chemistry Letters. 10: 1073-1076. PMID 10843220 DOI: 10.1016/S0960-894X(00)00167-0  0.786
2000 Huntington KM, Yi T, Wei Y, Pei D. Synthesis and antibacterial activity of peptide deformylase inhibitors Biochemistry. 39: 4543-4551. PMID 10758004 DOI: 10.1021/Bi992452Y  0.801
2000 Beebe KD, Shin J, Peng J, Chaudhury C, Khera J, Pei D. Substrate recognition through a PDZ domain in tail-specific protease. Biochemistry. 39: 3149-55. PMID 10715137 DOI: 10.1021/Bi992709S  0.788
1999 Huntington KM, Bienvenue DL, Wei Y, Bennett B, Holz RC, Pei D. Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization. Biochemistry. 38: 15587-96. PMID 10569943 DOI: 10.1021/Bi991283E  0.771
1999 Hu YJ, Wei Y, Zhou Y, Rajagopalan PT, Pei D. Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library. Biochemistry. 38: 643-50. PMID 9888804 DOI: 10.1021/Bi9820412  0.819
1999 Arabaci G, Guo XC, Beebe KD, Coggeshall KM, Pei D. α-haloacetophenone derivatives as photoreversible covalent inhibitors of protein tyrosine phosphatases Journal of the American Chemical Society. 121: 5085-5086. DOI: 10.1021/Ja9906756  0.776
1998 Wei Y, Yan Y, Pei D, Gong B. A photoactivated prodrug. Bioorganic & Medicinal Chemistry Letters. 8: 2419-22. PMID 9873553 DOI: 10.1016/S0960-894X(98)00437-5  0.743
1998 Beebe KD, Pei D. A continuous fluorimetric assay for tail-specific protease. Analytical Biochemistry. 263: 51-6. PMID 9750142 DOI: 10.1006/Abio.1998.2797  0.783
1998 Rajagopalan PTR, Pei D. Oxygen-mediated inactivation of peptide deformylase Journal of Biological Chemistry. 273: 22305-22310. PMID 9712848 DOI: 10.1074/Jbc.273.35.22305  0.374
1997 Rajagopalan PTR, Datta aA, Pei D. Purification, characterization, and inhibition of peptide deformylase from Escherichia coli. Biochemistry. 36: 13910-13918. PMID 9374870 DOI: 10.1021/Bi971155V  0.447
1997 Wei Y, Pei D. Continuous spectrophotometric assay of peptide deformylase. Analytical Biochemistry. 250: 29-34. PMID 9234895 DOI: 10.1006/Abio.1997.2194  0.796
1996 Kharbanda S, Bharti A, Pei D, Wang J, Pandey P, Ren R, Weichselbaum R, Walsh CT, Kufe D. The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1. Proceedings of the National Academy of Sciences of the United States of America. 93: 6898-901. PMID 8692915 DOI: 10.1073/Pnas.93.14.6898  0.554
1996 Pei D, Wang J, Walsh CT. Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1. Proceedings of the National Academy of Sciences of the United States of America. 93: 1141-5. PMID 8577729 DOI: 10.1073/Pnas.93.3.1141  0.6
1994 Payne G, Stolz LA, Pei D, Band H, Shoelson SE, Walsh CT. The phosphopeptide-binding specificity of Src family SH2 domains. Chemistry & Biology. 1: 99-105. PMID 9383377 DOI: 10.1016/1074-5521(94)90047-7  0.628
1994 Lorenz U, Ravichandran KS, Pei D, Walsh CT, Burakoff SJ, Neel BG. Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells. Molecular and Cellular Biology. 14: 1824-34. PMID 8114715 DOI: 10.1128/mcb.14.3.1824-1834.1994  0.541
1994 Pei D, Lorenz U, Klingmüller U, Neel BG, Walsh CT. Intramolecular regulation of protein tyrosine phosphatase SH-PTP1: a new function for Src homology 2 domains. Biochemistry. 33: 15483-93. PMID 7528537 DOI: 10.1021/Bi00255A030  0.611
1993 Pei D, Neel BG, Walsh CT. Overexpression, purification, and characterization of SHPTP1, a Src homology 2-containing protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 90: 1092-6. PMID 8430079 DOI: 10.1073/Pnas.90.3.1092  0.632
1991 Pei DH, Ulrich HD, Schultz PG. A combinatorial approach toward DNA recognition. Science (New York, N.Y.). 253: 1408-11. PMID 1716784 DOI: 10.1126/Science.1716784  0.706
1991 Pei D, Schultz PG. Engineering protein specificity: gene manipulation with semisynthetic nucleases Journal of the American Chemical Society. 113: 9398-9400. DOI: 10.1021/Ja00024A072  0.524
1990 Pei D, Corey DR, Schultz PG. Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix formation. Proceedings of the National Academy of Sciences of the United States of America. 87: 9858-62. PMID 2124705 DOI: 10.1073/Pnas.87.24.9858  0.666
1990 Pei D, Schultz PG. Site-specific cleavage of duplex DNA with a .lambda. repressor-staphylococcal nuclease hybrid Journal of the American Chemical Society. 112: 4579-4580. DOI: 10.1021/Ja00167A085  0.557
1989 Corey DR, Pei D, Schultz PG. Generation of a catalytic sequence-specific hybrid DNase. Biochemistry. 28: 8277-86. PMID 2605184 DOI: 10.1021/Bi00447A004  0.679
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