Jacob Ellery Corn - Publications

Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
 2007 University of California, Berkeley, Berkeley, CA, United States 
Genome editing and regulation for molecular mechanism and human health

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Riepe C, Zelin E, Frankino PA, Meacham ZA, Fernandez S, Ingolia NT, Corn JE. Double stranded DNA breaks and genome editing trigger loss of ribosomal protein RPS27A. The Febs Journal. PMID 34914197 DOI: 10.1111/febs.16321  0.342
2020 Shin JJ, Schröder MS, Caiado F, Wyman SK, Bray NL, Bordi M, Dewitt MA, Vu JT, Kim WT, Hockemeyer D, Manz MG, Corn JE. Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells. Cell Reports. 32: 108093. PMID 32877675 DOI: 10.1016/J.Celrep.2020.108093  0.301
2020 Wang AS, Chen LC, Wu RA, Hao Y, McSwiggen DT, Heckert AB, Richardson CD, Gowen BG, Kazane KR, Vu JT, Wyman SK, Shin JJ, Darzacq X, Walter JC, Corn JE. The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells. Molecular Cell. PMID 32603710 DOI: 10.1016/J.Molcel.2020.06.014  0.412
2020 Rose JC, Popp NA, Richardson CD, Stephany JJ, Mathieu J, Wei CT, Corn JE, Maly DJ, Fowler DM. Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs. Nature Communications. 11: 2697. PMID 32483117 DOI: 10.1038/S41467-020-16542-9  0.363
2020 Wienert B, Nguyen DN, Guenther A, Feng SJ, Locke MN, Wyman SK, Shin J, Kazane KR, Gregory GL, Carter MAM, Wright F, Conklin BR, Marson A, Richardson CD, Corn JE. Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair. Nature Communications. 11: 2109. PMID 32355159 DOI: 10.1038/S41467-020-15845-1  0.405
2020 Wienert B, Wyman SK, Yeh CD, Conklin BR, Corn JE. CRISPR off-target detection with DISCOVER-seq. Nature Protocols. PMID 32313254 DOI: 10.1038/S41596-020-0309-5  0.398
2019 Yeh CD, Richardson CD, Corn JE. Advances in genome editing through control of DNA repair pathways. Nature Cell Biology. PMID 31792376 DOI: 10.1038/S41556-019-0425-Z  0.373
2019 Luteijn RD, Zaver SA, Gowen BG, Wyman SK, Garelis NE, Onia L, McWhirter SM, Katibah GE, Corn JE, Woodward JJ, Raulet DH. SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 573: 434-438. PMID 31511694 DOI: 10.1038/S41586-019-1553-0  0.379
2019 Wienert B, Wyman SK, Richardson CD, Yeh CD, Akcakaya P, Porritt MJ, Morlock M, Vu JT, Kazane KR, Watry HL, Judge LM, Conklin BR, Maresca M, Corn JE. Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. Science (New York, N.Y.). 364: 286-289. PMID 31000663 DOI: 10.1126/Science.Aav9023  0.372
2018 Lomova A, Clark DN, Campo-Fernandez B, Flores-Bjurström C, Kaufman ML, Fitz-Gibbon S, Wang X, Miyahira EY, Brown D, DeWitt MA, Corn JE, Hollis RP, Romero Z, Kohn DB. Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. Stem Cells (Dayton, Ohio). PMID 30372555 DOI: 10.1002/Stem.2935  0.31
2018 Richardson CD, Kazane KR, Feng SJ, Zelin E, Bray NL, Schäfer AJ, Floor SN, Corn JE. CRISPR-Cas9 genome editing in human cells occurs via the Fanconi anemia pathway. Nature Genetics. PMID 30054595 DOI: 10.1038/S41588-018-0174-0  0.376
2018 Wienert B, Shin J, Zelin E, Pestal K, Corn JE. In vitro-transcribed guide RNAs trigger an innate immune response via the RIG-I pathway. Plos Biology. 16: e2005840. PMID 30011268 DOI: 10.1371/Journal.Pbio.2005840  0.333
2018 Farboud B, Jarvis E, Roth TL, Shin J, Corn JE, Marson A, Meyer BJ, Patel NH, Hochstrasser ML. Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms. Journal of Visualized Experiments : Jove. PMID 29889198 DOI: 10.3791/57350  0.44
2018 Stewart MD, Zelin E, Dhall A, Walsh T, Upadhyay E, Corn JE, Chatterjee C, King MC, Klevit RE. BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29367421 DOI: 10.1073/Pnas.1715467115  0.326
2017 Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, Mackley VA, Chang K, Rao A, Skinner C, Shobha T, Mehdipour M, Liu H, Huang WC, Lan F, ... ... Corn JE, et al. Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA induces homology-directed DNA repair. Nature Biomedical Engineering. 1: 889-901. PMID 29805845 DOI: 10.1038/S41551-017-0137-2  0.407
2017 Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Corn JE, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963  0.312
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Corn JE, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875  0.315
2017 Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA. Disabling Cas9 by an anti-CRISPR DNA mimic. Science Advances. 3: e1701620. PMID 28706995 DOI: 10.1126/Sciadv.1701620  0.458
2017 Lee K, Mackley VA, Rao A, Chong AT, Dewitt MA, Corn JE, Murthy N. Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering. Elife. 6. PMID 28462777 DOI: 10.7554/Elife.25312  0.424
2017 Biel JT, Thompson MC, Cunningham CN, Corn JE, Fraser JS. Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin. Structure (London, England : 1993). PMID 28416112 DOI: 10.1016/J.Str.2017.03.009  0.324
2017 DeWitt M, Corn JE, Carroll D. Genome editing via delivery of Cas9 ribonucleoprotein. Methods (San Diego, Calif.). PMID 28410976 DOI: 10.1016/J.Ymeth.2017.04.003  0.337
2017 Lee K, Mackley VA, Rao A, Chong AT, Dewitt MA, Corn JE, Murthy N. Author response: Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering Elife. DOI: 10.7554/Elife.25312.018  0.399
2016 DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Muñoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE. Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells. Science Translational Medicine. 8: 360ra134. PMID 27733558 DOI: 10.1126/Scitranslmed.Aaf9336  0.334
2016 Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 5. PMID 27661255 DOI: 10.7554/Elife.19760  0.369
2016 Richardson CD, Ray GJ, Bray NL, Corn JE. Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes. Nature Communications. 7: 12463. PMID 27530320 DOI: 10.1038/Ncomms12463  0.416
2016 Richardson CD, Ray GJ, DeWitt MA, Curie GL, Corn JE. Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA. Nature Biotechnology. PMID 26789497 DOI: 10.1038/Nbt.3481  0.412
2015 Lin PC, Corn JE. Co-opting CRISPR to deliver functional RNAs. Nature Methods. 12: 613-4. PMID 26125593 DOI: 10.1038/Nmeth.3452  0.309
2013 Mukund S, Shang Y, Clarke HJ, Madjidi A, Corn JE, Kates L, Kolumam G, Chiang V, Luis E, Murray J, Zhang Y, Hötzel I, Koth CM, Allan BB. Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. The Journal of Biological Chemistry. 288: 36168-78. PMID 24189067 DOI: 10.1074/Jbc.M113.496984  0.321
2013 Phillips AH, Zhang Y, Cunningham CN, Zhou L, Forrest WF, Liu PS, Steffek M, Lee J, Tam C, Helgason E, Murray JM, Kirkpatrick DS, Fairbrother WJ, Corn JE. Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 11379-84. PMID 23801757 DOI: 10.1073/Pnas.1302407110  0.341
2013 Zhang Y, Zhou L, Rouge L, Phillips AH, Lam C, Liu P, Sandoval W, Helgason E, Murray JM, Wertz IE, Corn JE. Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7. Nature Chemical Biology. 9: 51-8. PMID 23178935 DOI: 10.1038/Nchembio.1134  0.395
2012 Rymer RU, Solorio FA, Tehranchi AK, Chu C, Corn JE, Keck JL, Wang JD, Berger JM. Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases. Structure (London, England : 1993). 20: 1478-89. PMID 22795082 DOI: 10.1016/J.Str.2012.05.017  0.549
2011 Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, et al. Community-wide assessment of protein-interface modeling suggests improvements to design methodology. Journal of Molecular Biology. 414: 289-302. PMID 22001016 DOI: 10.1016/J.Jmb.2011.09.031  0.305
2011 Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Karanicolas J, Baker D. Hotspot-centric de novo design of protein binders. Journal of Molecular Biology. 413: 1047-62. PMID 21945116 DOI: 10.1016/J.Jmb.2011.09.001  0.309
2011 Bentley ML, Corn JE, Dong KC, Phung Q, Cheung TK, Cochran AG. Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. The Embo Journal. 30: 3285-97. PMID 21772249 DOI: 10.1038/Emboj.2011.243  0.688
2011 Fleishman SJ, Leaver-Fay A, Corn JE, Strauch EM, Khare SD, Koga N, Ashworth J, Murphy P, Richter F, Lemmon G, Meiler J, Baker D. RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite. Plos One. 6: e20161. PMID 21731610 DOI: 10.1371/Journal.Pone.0020161  0.355
2011 Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science (New York, N.Y.). 332: 816-21. PMID 21566186 DOI: 10.1126/Science.1202617  0.313
2011 Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. A de novo protein binding pair by computational design and directed evolution. Molecular Cell. 42: 250-60. PMID 21458342 DOI: 10.1016/J.Molcel.2011.03.010  0.309
2011 Dueber EC, Costa A, Corn JE, Bell SD, Berger JM. Molecular determinants of origin discrimination by Orc1 initiators in archaea. Nucleic Acids Research. 39: 3621-31. PMID 21227921 DOI: 10.1093/Nar/Gkq1308  0.647
2011 Bentley ML, Corn JE, Dong KC, Phung Q, Cheung TK, Cochran AG. Abstract A160: Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A160  0.714
2010 Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Andre I, Thompson J, Havranek JJ, Das R, Bradley P, Baker D. Rosetta in CAPRI rounds 13-19. Proteins. 78: 3212-8. PMID 20597089 DOI: 10.1002/Prot.22784  0.335
2010 Sabogal A, Lyubimov AY, Corn JE, Berger JM, Rio DC. THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves. Nature Structural & Molecular Biology. 17: 117-23. PMID 20010837 DOI: 10.1038/Nsmb.1742  0.628
2008 Larson MA, Bressani R, Sayood K, Corn JE, Berger JM, Griep MA, Hinrichs SH. Hyperthermophilic Aquifex aeolicus initiates primer synthesis on a limited set of trinucleotides comprised of cytosines and guanines. Nucleic Acids Research. 36: 5260-9. PMID 18684998 DOI: 10.1093/Nar/Gkn461  0.557
2008 Corn JE, Pelton JG, Berger JM. Identification of a DNA primase template tracking site redefines the geometry of primer synthesis. Nature Structural & Molecular Biology. 15: 163-9. PMID 18193061 DOI: 10.1038/Nsmb.1373  0.669
2007 Dueber EL, Corn JE, Bell SD, Berger JM. Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex. Science (New York, N.Y.). 317: 1210-3. PMID 17761879 DOI: 10.1126/Science.1143690  0.634
2007 Corn JE, Berger JM. FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studies. Structure (London, England : 1993). 15: 773-80. PMID 17637338 DOI: 10.1016/J.Str.2007.05.006  0.541
2006 Corn JE, Berger JM. Regulation of bacterial priming and daughter strand synthesis through helicase-primase interactions. Nucleic Acids Research. 34: 4082-8. PMID 16935873 DOI: 10.1093/Nar/Gkl363  0.616
2005 Corn JE, Pease PJ, Hura GL, Berger JM. Crosstalk between primase subunits can act to regulate primer synthesis in trans. Molecular Cell. 20: 391-401. PMID 16285921 DOI: 10.1016/J.Molcel.2005.09.004  0.621
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