Richard E. Lenski, Ph.D. - Publications

Affiliations: 
Microbiology and Molecular Genetics Michigan State University, East Lansing, MI 
Area:
Evolution, microbial ecology, microbiology
Website:
http://lenski.mmg.msu.edu/index.html

237 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Izutsu M, Lake DM, Matson ZWD, Dodson JP, Lenski RE. Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations. Microbiology (Reading, England). 170. PMID 39292609 DOI: 10.1099/mic.0.001494  0.846
2024 Couce A, Limdi A, Magnan M, Owen SV, Herren CM, Lenski RE, Tenaillon O, Baym M. Changing fitness effects of mutations through long-term bacterial evolution. Science (New York, N.Y.). 383: eadd1417. PMID 38271521 DOI: 10.1126/science.add1417  0.373
2023 Rodríguez-Pastor R, Hasik AZ, Knossow N, Bar-Shira E, Shahar N, Gutiérrez R, Zaman L, Harrus S, Lenski RE, Barrick JE, Hawlena H. Bartonella infections are prevalent in rodents despite efficient immune responses. Parasites & Vectors. 16: 315. PMID 37667323 DOI: 10.1186/s13071-023-05918-7  0.784
2023 Turner CB, Blount ZD, Mitchell DH, Lenski RE. Evolution of a cross-feeding interaction following a key innovation in a long-term evolution experiment with . Microbiology (Reading, England). 169. PMID 37650867 DOI: 10.1099/mic.0.001390  0.827
2022 Rodríguez-Pastor R, Shafran Y, Knossow N, Gutiérrez R, Harrus S, Zaman L, Lenski RE, Barrick JE, Hawlena H. A road map for in vivo evolution experiments with blood-borne parasitic microbes. Molecular Ecology Resources. PMID 35599628 DOI: 10.1111/1755-0998.13649  0.785
2022 Jordan JA, Lenski RE, Card KJ. Idiosyncratic Fitness Costs of Ampicillin-Resistant Mutants Derived from a Long-Term Experiment with . Antibiotics (Basel, Switzerland). 11. PMID 35326810 DOI: 10.3390/antibiotics11030347  0.808
2021 Grant NA, Maddamsetti R, Lenski RE. Maintenance of Metabolic Plasticity despite Relaxed Selection in a Long-Term Evolution Experiment with . The American Naturalist. 198: 93-112. PMID 34143718 DOI: 10.1086/714530  0.828
2021 Burmeister AR, Sullivan RM, Gallie J, Lenski RE. Sustained coevolution of phage Lambda and involves inner- as well as outer-membrane defences and counter-defences. Microbiology (Reading, England). 167. PMID 34032565 DOI: 10.1099/mic.0.001063  0.744
2021 Grant NA, Abdel Magid A, Franklin J, Dufour Y, Lenski RE. Changes in Cell Size and Shape During 50,000 Generations of Experimental Evolution with . Journal of Bacteriology. PMID 33649147 DOI: 10.1128/JB.00469-20  0.81
2021 Card KJ, Jordan JA, Lenski RE. Idiosyncratic variation in the fitness costs of tetracycline-resistance mutations in Escherichia coli. Evolution; International Journal of Organic Evolution. PMID 33634468 DOI: 10.1111/evo.14203  0.813
2021 Consuegra J, Gaffé J, Lenski RE, Hindré T, Barrick JE, Tenaillon O, Schneider D. Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria. Nature Communications. 12: 980. PMID 33579917 DOI: 10.1038/s41467-021-21210-7  0.812
2021 Card KJ, Thomas MD, Graves JL, Barrick JE, Lenski RE. Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33441451 DOI: 10.1073/pnas.2016886118  0.823
2020 Blount ZD, Maddamsetti R, Grant NA, Ahmed ST, Jagdish T, Baxter JA, Sommerfeld BA, Tillman A, Moore J, Slonczewski JL, Barrick JE, Lenski RE. Genomic and phenotypic evolution of in a novel citrate-only resource environment. Elife. 9. PMID 32469311 DOI: 10.7554/Elife.55414  0.83
2020 Blount ZD, Maddamsetti R, Grant NA, Ahmed ST, Jagdish T, Baxter JA, Sommerfeld BA, Tillman A, Moore J, Slonczewski JL, Barrick JE, Lenski RE. Author response: Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment Elife. DOI: 10.7554/Elife.55414.Sa2  0.79
2019 Card KJ, LaBar T, Gomez JB, Lenski RE. Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection. Plos Biology. 17: e3000397. PMID 31644535 DOI: 10.1371/Journal.Pbio.3000397  0.83
2019 Lamrabet O, Martin M, Lenski RE, Schneider D. Changes in Intrinsic Antibiotic Susceptibility during a Long-Term Evolution Experiment with Escherichia coli. Mbio. 10. PMID 30837336 DOI: 10.1128/Mbio.00189-19  0.543
2019 Lamrabet O, Plumbridge J, Martin M, Lenski RE, Schneider D, Hindré T. Plasticity of Promoter-Core Sequences Allows Bacteria to Compensate for the Loss of a Key Global Regulatory Gene. Molecular Biology and Evolution. PMID 30825312 DOI: 10.1093/Molbev/Msz042  0.606
2018 Blount ZD, Lenski RE, Losos JB. Contingency and determinism in evolution: Replaying life's tape. Science (New York, N.Y.). 362. PMID 30409860 DOI: 10.1126/Science.Aam5979  0.819
2018 Maddamsetti R, Lenski RE. Analysis of bacterial genomes from an evolution experiment with horizontal gene transfer shows that recombination can sometimes overwhelm selection. Plos Genetics. 14: e1007199. PMID 29385126 DOI: 10.1371/Journal.Pgen.1007199  0.78
2018 Burmeister AR, Lenski RE. Specifying the Harsh Conditions of Life: Resource Competition and Predation in the 1970s The American Naturalist. 191: 287-289. DOI: 10.1086/695985  0.734
2017 Couce A, Caudwell LV, Feinauer C, Hindré T, Feugeas JP, Weigt M, Lenski RE, Schneider D, Tenaillon O. Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria. Proceedings of the National Academy of Sciences of the United States of America. 114: E9026-E9035. PMID 29073099 DOI: 10.1073/Pnas.1705887114  0.649
2017 Peng F, Widmann S, Wünsche A, Duan K, Donovan KA, Dobson RCJ, Lenski RE, Cooper TF. Effects of beneficial mutations in pykF gene vary over time and across replicate populations in a long-term experiment with bacteria. Molecular Biology and Evolution. PMID 29069429 DOI: 10.1093/Molbev/Msx279  0.687
2017 Good BH, McDonald MJ, Barrick JE, Lenski RE, Desai MM. The dynamics of molecular evolution over 60,000 generations. Nature. PMID 29045390 DOI: 10.1038/Nature24287  0.775
2017 Turner CB, Wade BD, Meyer JR, Sommerfeld BA, Lenski RE. Evolution of organismal stoichiometry in a long-term experiment with Escherichia coli. Royal Society Open Science. 4: 170497. PMID 28791173 DOI: 10.1098/Rsos.170497  0.772
2017 Lenski RE. Convergence and Divergence in a Long-Term Experiment with Bacteria. The American Naturalist. 190: S57-S68. PMID 28731830 DOI: 10.1086/691209  0.48
2017 Lenski RE. Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations. The Isme Journal. PMID 28509909 DOI: 10.1038/Ismej.2017.69  0.494
2017 Lenski RE. What is adaptation by natural selection? Perspectives of an experimental microbiologist. Plos Genetics. 13: e1006668. PMID 28426692 DOI: 10.1371/Journal.Pgen.1006668  0.413
2017 Maddamsetti R, Hatcher PJ, Green AG, Williams BL, Marks DS, Lenski RE. Core Genes Evolve Rapidly in the Long-term Evolution Experiment with Escherichia coli. Genome Biology and Evolution. PMID 28379360 DOI: 10.1093/Gbe/Evx064  0.773
2017 Deatherage DE, Kepner JL, Bennett AF, Lenski RE, Barrick JE. Specificity of genome evolution in experimental populations of Escherichia coli evolved at different temperatures. Proceedings of the National Academy of Sciences of the United States of America. PMID 28202733 DOI: 10.1073/Pnas.1616132114  0.819
2017 Lenski RE, Burnham TC. Experimental evolution of bacteria across 60,000 generations, and what it might mean for economics and human decision-making Journal of Bioeconomics. 20: 107-124. DOI: 10.1007/S10818-017-9258-7  0.365
2016 Meyer JR, Dobias DT, Medina SJ, Servilio L, Gupta A, Lenski RE. Ecological speciation of bacteriophage lambda in allopatry and sympatry. Science (New York, N.Y.). PMID 27884940 DOI: 10.1126/Science.Aai8446  0.762
2016 Burmeister AR, Lenski RE, Meyer JR. Host coevolution alters the adaptive landscape of a virus. Proceedings. Biological Sciences. 283. PMID 27683370 DOI: 10.1098/Rspb.2016.1528  0.808
2016 Großkopf T, Consuegra J, Gaffé J, Willison JC, Lenski RE, Soyer OS, Schneider D. Metabolic modelling in a dynamic evolutionary framework predicts adaptive diversification of bacteria in a long-term evolution experiment. Bmc Evolutionary Biology. 16: 163. PMID 27544664 DOI: 10.1186/S12862-016-0733-X  0.555
2016 Tenaillon O, Barrick JE, Ribeck N, Deatherage DE, Blanchard JL, Dasgupta A, Wu GC, Wielgoss S, Cruveiller S, Médigue C, Schneider D, Lenski RE. Tempo and mode of genome evolution in a 50,000-generation experiment. Nature. PMID 27479321 DOI: 10.1038/Nature18959  0.843
2016 Bergstrom CT, Wasik BR, Lenski RE. You lookin' at me? British Journal of Clinical Pharmacology. PMID 27412641 DOI: 10.1111/Bcp.13036  0.764
2015 Lenski RE, Wiser MJ, Ribeck N, Blount ZD, Nahum JR, Morris JJ, Zaman L, Turner CB, Wade BD, Maddamsetti R, Burmeister AR, Baird EJ, Bundy J, Grant NA, Card KJ, et al. Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli. Proceedings. Biological Sciences / the Royal Society. 282. PMID 26674951 DOI: 10.1098/Rspb.2015.2292  0.783
2015 Turner CB, Blount ZD, Lenski RE. Replaying Evolution to Test the Cause of Extinction of One Ecotype in an Experimentally Evolved Population. Plos One. 10: e0142050. PMID 26581098 DOI: 10.1371/Journal.Pone.0142050  0.824
2015 Maddamsetti R, Hatcher PJ, Cruveiller S, Médigue C, Barrick JE, Lenski RE. Synonymous Genetic Variation in Natural Isolates of Escherichia coli Does Not Predict Where Synonymous Substitutions Occur in a Long-Term Experiment. Molecular Biology and Evolution. 32: 2897-904. PMID 26199375 DOI: 10.1093/Molbev/Msv161  0.834
2015 Fox JW, Lenski RE. From Here to Eternity-The Theory and Practice of a Really Long Experiment. Plos Biology. 13: e1002185. PMID 26102073 DOI: 10.1371/Journal.Pbio.1002185  0.355
2015 Ostrowski EA, Ofria C, Lenski RE. Genetically integrated traits and rugged adaptive landscapes in digital organisms. Bmc Evolutionary Biology. 15: 83. PMID 25963618 DOI: 10.1186/S12862-015-0361-X  0.816
2015 Wiser MJ, Lenski RE. A Comparison of Methods to Measure Fitness in Escherichia coli. Plos One. 10: e0126210. PMID 25961572 DOI: 10.1371/Journal.Pone.0126210  0.812
2015 Maddamsetti R, Lenski RE, Barrick JE. Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli. Genetics. 200: 619-31. PMID 25911659 DOI: 10.1534/Genetics.115.176677  0.848
2015 Ribeck N, Lenski RE. Modeling and quantifying frequency-dependent fitness in microbial populations with cross-feeding interactions. Evolution; International Journal of Organic Evolution. 69: 1313-20. PMID 25787308 DOI: 10.1111/Evo.12645  0.807
2014 Zaman L, Meyer JR, Devangam S, Bryson DM, Lenski RE, Ofria C. Coevolution drives the emergence of complex traits and promotes evolvability. Plos Biology. 12: e1002023. PMID 25514332 DOI: 10.1371/Journal.Pbio.1002023  0.805
2014 Raeside C, Gaffé J, Deatherage DE, Tenaillon O, Briska AM, Ptashkin RN, Cruveiller S, Médigue C, Lenski RE, Barrick JE, Schneider D. Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli. Mbio. 5: e01377-14. PMID 25205090 DOI: 10.1128/Mbio.01377-14  0.792
2014 Morris JJ, Papoulis SE, Lenski RE. Coexistence of evolving bacteria stabilized by a shared Black Queen function. Evolution; International Journal of Organic Evolution. 68: 2960-71. PMID 24989794 DOI: 10.1111/Evo.12485  0.503
2014 Plucain J, Hindré T, Le Gac M, Tenaillon O, Cruveiller S, Médigue C, Leiby N, Harcombe WR, Marx CJ, Lenski RE, Schneider D. Epistasis and allele specificity in the emergence of a stable polymorphism in Escherichia coli. Science (New York, N.Y.). 343: 1366-9. PMID 24603152 DOI: 10.1126/Science.1248688  0.839
2013 Wiser MJ, Ribeck N, Lenski RE. Long-term dynamics of adaptation in asexual populations. Science (New York, N.Y.). 342: 1364-7. PMID 24231808 DOI: 10.1126/Science.1243357  0.808
2013 Barrick JE, Lenski RE. Genome dynamics during experimental evolution. Nature Reviews. Genetics. 14: 827-39. PMID 24166031 DOI: 10.1038/Nrg3564  0.766
2013 Covert AW, Lenski RE, Wilke CO, Ofria C. Experiments on the role of deleterious mutations as stepping stones in adaptive evolution. Proceedings of the National Academy of Sciences of the United States of America. 110: E3171-8. PMID 23918358 DOI: 10.1073/Pnas.1313424110  0.832
2013 Wielgoss S, Barrick JE, Tenaillon O, Wiser MJ, Dittmar WJ, Cruveiller S, Chane-Woon-Ming B, Médigue C, Lenski RE, Schneider D. Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load. Proceedings of the National Academy of Sciences of the United States of America. 110: 222-7. PMID 23248287 DOI: 10.1073/Pnas.1219574110  0.835
2012 Blount ZD, Barrick JE, Davidson CJ, Lenski RE. Genomic analysis of a key innovation in an experimental Escherichia coli population. Nature. 489: 513-8. PMID 22992527 DOI: 10.1038/Nature11514  0.836
2012 Clune J, Pennock RT, Ofria C, Lenski RE. Ontogeny tends to recapitulate phylogeny in digital organisms. The American Naturalist. 180: E54-63. PMID 22854085 DOI: 10.1086/666984  0.792
2012 Kawecki TJ, Lenski RE, Ebert D, Hollis B, Olivieri I, Whitlock MC. Experimental evolution. Trends in Ecology & Evolution. 27: 547-60. PMID 22819306 DOI: 10.1016/j.tree.2012.06.001  0.81
2012 Le Gac M, Plucain J, Hindré T, Lenski RE, Schneider D. Ecological and evolutionary dynamics of coexisting lineages during a long-term experiment with Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 109: 9487-92. PMID 22645336 DOI: 10.1073/Pnas.1207091109  0.542
2012 Morris JJ, Lenski RE, Zinser ER. The Black Queen Hypothesis: evolution of dependencies through adaptive gene loss. Mbio. 3. PMID 22448042 DOI: 10.1128/Mbio.00036-12  0.783
2012 Meyer JR, Dobias DT, Weitz JS, Barrick JE, Quick RT, Lenski RE. Repeatability and contingency in the evolution of a key innovation in phage lambda. Science (New York, N.Y.). 335: 428-32. PMID 22282803 DOI: 10.1126/Science.1214449  0.823
2012 Zaman L, Ofria C, Lenski RE. Finger-painting fitness landscapes: An interactive tool for exploring complex evolutionary dynamics Artificial Life 13: Proceedings of the 13th International Conference On the Simulation and Synthesis of Living Systems, Alife 2012. 499-505. DOI: 10.7551/978-0-262-31050-5-Ch065  0.811
2012 Kawecki TJ, Lenski RE, Ebert D, Hollis B, Olivieri I, Whitlock MC. The value of complementary approaches in evolutionary research: Reply to Magalhães and Matos Trends in Ecology and Evolution. 27: 650-651. DOI: 10.1016/J.Tree.2012.09.007  0.778
2012 Ofria C, Adami C, Brown A, Bryson DM, Goodman E, James C, Kelsaw T, Lenski R, McKinley P, Pennock RT, Whittaker D. Preface Artificial Life 13: Proceedings of the 13th International Conference On the Simulation and Synthesis of Living Systems, Alife 2012. xv-xx.  0.739
2011 Wielgoss S, Barrick JE, Tenaillon O, Cruveiller S, Chane-Woon-Ming B, Médigue C, Lenski RE, Schneider D. Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli. G3 (Bethesda, Md.). 1: 183-186. PMID 22207905 DOI: 10.1534/G3.111.000406  0.818
2011 Lenski RE. Chance and necessity in the evolution of a bacterial pathogen. Nature Genetics. 43: 1174-6. PMID 22120052 DOI: 10.1038/Ng.1011  0.363
2011 Khan AI, Dinh DM, Schneider D, Lenski RE, Cooper TF. Negative epistasis between beneficial mutations in an evolving bacterial population. Science (New York, N.Y.). 332: 1193-6. PMID 21636772 DOI: 10.1126/Science.1203801  0.844
2011 Woods RJ, Barrick JE, Cooper TF, Shrestha U, Kauth MR, Lenski RE. Second-order selection for evolvability in a large Escherichia coli population. Science (New York, N.Y.). 331: 1433-6. PMID 21415350 DOI: 10.1126/Science.1198914  0.855
2011 Crozat E, Hindré T, Kühn L, Garin J, Lenski RE, Schneider D. Altered regulation of the OmpF porin by Fis in Escherichia coli during an evolution experiment and between B and K-12 strains. Journal of Bacteriology. 193: 429-40. PMID 21097626 DOI: 10.1128/Jb.01341-10  0.561
2010 Strelioff CC, Lenski RE, Ofria C. Evolutionary dynamics, epistatic interactions, and biological information. Journal of Theoretical Biology. 266: 584-94. PMID 20659477 DOI: 10.1016/J.Jtbi.2010.07.025  0.806
2010 Meyer JR, Agrawal AA, Quick RT, Dobias DT, Schneider D, Lenski RE. Parallel changes in host resistance to viral infection during 45,000 generations of relaxed selection. Evolution; International Journal of Organic Evolution. 64: 3024-34. PMID 20550574 DOI: 10.1111/J.1558-5646.2010.01049.X  0.708
2010 Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, ... ... Lenski RE, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/Science.328.5979.689  0.522
2010 Crozat E, Winkworth C, Gaffé J, Hallin PF, Riley MA, Lenski RE, Schneider D. Parallel genetic and phenotypic evolution of DNA superhelicity in experimental populations of Escherichia coli. Molecular Biology and Evolution. 27: 2113-28. PMID 20392810 DOI: 10.1093/Molbev/Msq099  0.707
2010 Misevic D, Ofria C, Lenski RE. Experiments with digital organisms on the origin and maintenance of sex in changing environments. The Journal of Heredity. 101: S46-54. PMID 20200140 DOI: 10.1093/Jhered/Esq017  0.796
2010 Barrick JE, Kauth MR, Strelioff CC, Lenski RE. Escherichia coli rpoB mutants have increased evolvability in proportion to their fitness defects. Molecular Biology and Evolution. 27: 1338-47. PMID 20106907 DOI: 10.1093/Molbev/Msq024  0.843
2010 Cooper TF, Lenski RE. Experimental evolution with E. coli in diverse resource environments. I. Fluctuating environments promote divergence of replicate populations. Bmc Evolutionary Biology. 10: 11. PMID 20070898 DOI: 10.1186/1471-2148-10-11  0.648
2009 Stanek MT, Cooper TF, Lenski RE. Identification and dynamics of a beneficial mutation in a long-term evolution experiment with Escherichia coli. Bmc Evolutionary Biology. 9: 302. PMID 20040094 DOI: 10.1186/1471-2148-9-302  0.678
2009 Barrick JE, Yu DS, Yoon SH, Jeong H, Oh TK, Schneider D, Lenski RE, Kim JF. Genome evolution and adaptation in a long-term experiment with Escherichia coli. Nature. 461: 1243-7. PMID 19838166 DOI: 10.1038/Nature08480  0.83
2009 Jeong H, Barbe V, Lee CH, Vallenet D, Yu DS, Choi SH, Couloux A, Lee SW, Yoon SH, Cattolico L, Hur CG, Park HS, Ségurens B, Kim SC, Oh TK, ... Lenski RE, et al. Genome sequences of Escherichia coli B strains REL606 and BL21(DE3). Journal of Molecular Biology. 394: 644-52. PMID 19786035 DOI: 10.1016/J.Jmb.2009.09.052  0.679
2009 Barrick JE, Lenski RE. Genome-wide mutational diversity in an evolving population of Escherichia coli. Cold Spring Harbor Symposia On Quantitative Biology. 74: 119-29. PMID 19776167 DOI: 10.1101/Sqb.2009.74.018  0.794
2009 Studier FW, Daegelen P, Lenski RE, Maslov S, Kim JF. Understanding the differences between genome sequences of Escherichia coli B strains REL606 and BL21(DE3) and comparison of the E. coli B and K-12 genomes. Journal of Molecular Biology. 394: 653-80. PMID 19765592 DOI: 10.1016/J.Jmb.2009.09.021  0.686
2009 Daegelen P, Studier FW, Lenski RE, Cure S, Kim JF. Tracing ancestors and relatives of Escherichia coli B, and the derivation of B strains REL606 and BL21(DE3). Journal of Molecular Biology. 394: 634-43. PMID 19765591 DOI: 10.1016/J.Jmb.2009.09.022  0.643
2009 Yedid G, Ofria CA, Lenski RE. Selective press extinctions, but not random pulse extinctions, cause delayed ecological recovery in communities of digital organisms. The American Naturalist. 173: E139-54. PMID 19220147 DOI: 10.1086/597228  0.788
2009 Philippe N, Pelosi L, Lenski RE, Schneider D. Evolution of penicillin-binding protein 2 concentration and cell shape during a long-term experiment with Escherichia coli. Journal of Bacteriology. 191: 909-21. PMID 19047356 DOI: 10.1128/Jb.01419-08  0.632
2009 Rozen DE, Philippe N, Arjan de Visser J, Lenski RE, Schneider D. Death and cannibalism in a seasonal environment facilitate bacterial coexistence. Ecology Letters. 12: 34-44. PMID 19019196 DOI: 10.1111/J.1461-0248.2008.01257.X  0.699
2009 Hillesland KL, Velicer GJ, Lenski RE. Experimental evolution of a microbial predator's ability to find prey. Proceedings. Biological Sciences / the Royal Society. 276: 459-67. PMID 18832061 DOI: 10.1098/Rspb.2008.1098  0.803
2008 Clune J, Misevic D, Ofria C, Lenski RE, Elena SF, Sanjuán R. Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes. Plos Computational Biology. 4: e1000187. PMID 18818724 DOI: 10.1371/journal.pcbi.1000187  0.824
2008 Sleight SC, Orlic C, Schneider D, Lenski RE. Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth. Genetics. 180: 431-43. PMID 18757947 DOI: 10.1534/Genetics.108.091330  0.822
2008 Yedid G, Ofria CA, Lenski RE. Historical and contingent factors affect re-evolution of a complex feature lost during mass extinction in communities of digital organisms. Journal of Evolutionary Biology. 21: 1335-57. PMID 18564346 DOI: 10.1111/J.1420-9101.2008.01564.X  0.813
2008 Blount ZD, Borland CZ, Lenski RE. Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 105: 7899-906. PMID 18524956 DOI: 10.1073/Pnas.0803151105  0.85
2008 Cooper TF, Remold SK, Lenski RE, Schneider D. Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli. Plos Genetics. 4: e35. PMID 18282111 DOI: 10.1371/Journal.Pgen.0040035  0.824
2008 Ostrowski EA, Woods RJ, Lenski RE. The genetic basis of parallel and divergent phenotypic responses in evolving populations of Escherichia coli. Proceedings. Biological Sciences / the Royal Society. 275: 277-84. PMID 18029306 DOI: 10.1098/Rspb.2007.1244  0.844
2007 Yoshida T, Ellner SP, Jones LE, Bohannan BJ, Lenski RE, Hairston NG. Cryptic population dynamics: rapid evolution masks trophic interactions. Plos Biology. 5: e235. PMID 17803356 DOI: 10.1371/Journal.Pbio.0050235  0.739
2007 Philippe N, Crozat E, Lenski RE, Schneider D. Evolution of global regulatory networks during a long-term experiment with Escherichia coli. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 846-60. PMID 17691099 DOI: 10.1002/Bies.20629  0.641
2007 Sleight SC, Lenski RE. Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. Physiological and Biochemical Zoology : Pbz. 80: 370-85. PMID 17508333 DOI: 10.1086/518013  0.687
2007 Bennett AF, Lenski RE. An experimental test of evolutionary trade-offs during temperature adaptation. Proceedings of the National Academy of Sciences of the United States of America. 104: 8649-54. PMID 17494741 DOI: 10.1073/Pnas.0702117104  0.587
2007 Beerenwinkel N, Pachter L, Sturmfels B, Elena SF, Lenski RE. Analysis of epistatic interactions and fitness landscapes using a new geometric approach. Bmc Evolutionary Biology. 7: 60. PMID 17433106 DOI: 10.1186/1471-2148-7-60  0.781
2007 Hillesland KL, Lenski RE, Velicer GJ. Ecological variables affecting predatory success in Myxococcus xanthus. Microbial Ecology. 53: 571-8. PMID 17410395 DOI: 10.1007/S00248-006-9111-3  0.776
2007 Elena SF, Wilke CO, Ofria C, Lenski RE. Effects of population size and mutation rate on the evolution of mutational robustness. Evolution; International Journal of Organic Evolution. 61: 666-74. PMID 17348929 DOI: 10.1111/J.1558-5646.2007.00064.X  0.84
2007 Ostrowski EA, Ofria C, Lenski RE. Ecological specialization and adaptive decay in digital organisms. The American Naturalist. 169: E1-20. PMID 17206577 DOI: 10.1086/510211  0.807
2006 Lenski RE, Barrick JE, Ofria C. Balancing robustness and evolvability. Plos Biology. 4: e428. PMID 17238277 DOI: 10.1371/Journal.Pbio.0040428  0.781
2006 Sleight SC, Wigginton NS, Lenski RE. Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. Bmc Evolutionary Biology. 6: 104. PMID 17147797 DOI: 10.1186/1471-2148-6-104  0.641
2006 Novak M, Pfeiffer T, Lenski RE, Sauer U, Bonhoeffer S. Experimental tests for an evolutionary trade-off between growth rate and yield in E. coli. The American Naturalist. 168: 242-51. PMID 16874633 DOI: 10.1086/506527  0.708
2006 Woods R, Schneider D, Winkworth CL, Riley MA, Lenski RE. Tests of parallel molecular evolution in a long-term experiment with Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 103: 9107-12. PMID 16751270 DOI: 10.1073/Pnas.0602917103  0.771
2006 Pelosi L, Kühn L, Guetta D, Garin J, Geiselmann J, Lenski RE, Schneider D. Parallel changes in global protein profiles during long-term experimental evolution in Escherichia coli. Genetics. 173: 1851-69. PMID 16702438 DOI: 10.1534/Genetics.105.049619  0.618
2006 Misevic D, Ofria C, Lenski RE. Sexual reproduction reshapes the genetic architecture of digital organisms. Proceedings. Biological Sciences / the Royal Society. 273: 457-64. PMID 16615213 DOI: 10.1098/Rspb.2005.3338  0.815
2005 Elena SF, Whittam TS, Winkworth CL, Riley MA, Lenski RE. Genomic divergence of Escherichia coli strains: evidence for horizontal transfer and variation in mutation rates. International Microbiology : the Official Journal of the Spanish Society For Microbiology. 8: 271-8. PMID 16562379  0.502
2005 Ostrowski EA, Rozen DE, Lenski RE. Pleiotropic effects of beneficial mutations in Escherichia coli. Evolution; International Journal of Organic Evolution. 59: 2343-52. PMID 16396175 DOI: 10.1111/J.0014-3820.2005.Tb00944.X  0.83
2005 Rozen DE, Schneider D, Lenski RE. Long-term experimental evolution in Escherichia coli. XIII. Phylogenetic history of a balanced polymorphism. Journal of Molecular Evolution. 61: 171-80. PMID 15999245 DOI: 10.1007/S00239-004-0322-2  0.7
2005 Cooper TF, Lenski RE, Elena SF. Parasites and mutational load: an experimental test of a pluralistic theory for the evolution of sex. Proceedings. Biological Sciences / the Royal Society. 272: 311-7. PMID 15705557 DOI: 10.1098/Rspb.2004.2975  0.625
2005 Crozat E, Philippe N, Lenski RE, Geiselmann J, Schneider D. Long-term experimental evolution in Escherichia coli. XII. DNA topology as a key target of selection. Genetics. 169: 523-32. PMID 15489515 DOI: 10.1534/Genetics.104.035717  0.624
2005 Eldredge N, Thompson JN, Brakefield PM, Gavrilets S, Jablonski D, Jackson JBC, Lenski RE, Lieberman BS, McPeek MA, Miller W. The dynamics of evolutionary stasis Paleobiology. 31: 133-145. DOI: 10.1666/0094-8373(2005)031[0133:Tdoes]2.0.Co;2  0.785
2004 Chow SS, Wilke CO, Ofria C, Lenski RE, Adami C. Adaptive radiation from resource competition in digital organisms. Science (New York, N.Y.). 305: 84-6. PMID 15232105 DOI: 10.1126/Science.1096307  0.805
2004 Schneider D, Lenski RE. Dynamics of insertion sequence elements during experimental evolution of bacteria. Research in Microbiology. 155: 319-27. PMID 15207863 DOI: 10.1016/J.Resmic.2003.12.008  0.56
2004 Remold SK, Lenski RE. Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli. Nature Genetics. 36: 423-6. PMID 15072075 DOI: 10.1038/Ng1324  0.836
2003 Lenski R. The ecology, genetics and evolution of bacteria in an experimental setting Current Biology : Cb. 13: R466-467. PMID 12814560 DOI: 10.1016/S0960-9822(03)00401-9  0.448
2003 Elena SF, Lenski RE. Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation. Nature Reviews. Genetics. 4: 457-69. PMID 12776215 DOI: 10.1038/Nrg1088  0.502
2003 Lenski RE, Ofria C, Pennock RT, Adami C. The evolutionary origin of complex features. Nature. 423: 139-44. PMID 12736677 DOI: 10.1038/Nature01568  0.818
2003 Riehle MM, Bennett AF, Lenski RE, Long AD. Evolutionary changes in heat-inducible gene expression in lines of Escherichia coli adapted to high temperature. Physiological Genomics. 14: 47-58. PMID 12672900 DOI: 10.1152/Physiolgenomics.00034.2002  0.54
2003 Lenski RE, Winkworth CL, Riley MA. Rates of DNA sequence evolution in experimental populations of Escherichia coli during 20,000 generations. Journal of Molecular Evolution. 56: 498-508. PMID 12664169 DOI: 10.1007/S00239-002-2423-0  0.659
2003 Wilke CO, Lenski RE, Adami C. Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding. Bmc Evolutionary Biology. 3: 3. PMID 12590655 DOI: 10.1186/1471-2148-3-3  0.763
2003 Cooper TF, Rozen DE, Lenski RE. Parallel changes in gene expression after 20,000 generations of evolution in Escherichiacoli. Proceedings of the National Academy of Sciences of the United States of America. 100: 1072-7. PMID 12538876 DOI: 10.1073/Pnas.0334340100  0.76
2002 de Visser JA, Lenski RE. Long-term experimental evolution in Escherichia coli. XI. Rejection of non-transitive interactions as cause of declining rate of adaptation. Bmc Evolutionary Biology. 2: 19. PMID 12443537 DOI: 10.1186/1471-2148-2-19  0.471
2002 Schneider D, Duperchy E, Depeyrot J, Coursange E, Lenski R, Blot M. Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers. Bmc Microbiology. 2: 18. PMID 12106505 DOI: 10.1186/1471-2180-2-18  0.723
2002 Velicer GJ, Lenski RE, Kroos L. Rescue of social motility lost during evolution of Myxococcus xanthus in an asocial environment. Journal of Bacteriology. 184: 2719-27. PMID 11976301 DOI: 10.1128/Jb.184.10.2719-2727.2002  0.837
2002 Lenski RE, Riley MA. Chemical warfare from an ecological perspective. Proceedings of the National Academy of Sciences of the United States of America. 99: 556-8. PMID 11805313 DOI: 10.1073/Pnas.022641999  0.541
2002 Schneider D, Duperchy E, Depeyrot J, Coursange E, Lenski RE, Blot M. Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7using IS elements as molecular markers Bmc Microbiology. 2: 1-8. DOI: 10.1186/1471-2180-2-1  0.691
2001 Cullum AJ, Bennett AF, Lenski RE. Evolutionary adaptation to temperature. IX. Preadaptation to novel stressful environments of Escherichia coli adapted to high temperature. Evolution; International Journal of Organic Evolution. 55: 2194-202. PMID 11794780 DOI: 10.1111/J.0014-3820.2001.Tb00735.X  0.791
2001 Elena SF, Lenski RE. Epistasis between new mutations and genetic background and a test of genetic canalization. Evolution; International Journal of Organic Evolution. 55: 1746-52. PMID 11681730 DOI: 10.1111/J.0014-3820.2001.Tb00824.X  0.473
2001 Lenski RE. Genetics and evolution. Come fly, and leave the baggage behind. Science (New York, N.Y.). 294: 533-4. PMID 11641486 DOI: 10.1126/Science.1066241  0.395
2001 Remold SK, Lenski RE. Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 98: 11388-93. PMID 11572987 DOI: 10.1073/Pnas.201140198  0.83
2001 Wilke CO, Wang JL, Ofria C, Lenski RE, Adami C. Evolution of digital organisms at high mutation rates leads to survival of the flattest. Nature. 412: 331-3. PMID 11460163 DOI: 10.1038/35085569  0.831
2001 Cooper VS, Bennett AF, Lenski RE. Evolution of thermal dependence of growth rate of Escherichia coli populations during 20,000 generations in a constant environment. Evolution; International Journal of Organic Evolution. 55: 889-96. PMID 11430649 DOI: 10.1554/0014-3820(2001)055[0889:Eotdog]2.0.Co;2  0.722
2001 Cooper VS, Schneider D, Blot M, Lenski RE. Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B. Journal of Bacteriology. 183: 2834-41. PMID 11292803 DOI: 10.1128/Jb.183.9.2834-2841.2001  0.824
2001 Riley MS, Cooper VS, Lenski RE, Forney LJ, Marsh TL. Rapid phenotypic change and diversification of a soil bacterium during 1000 generations of experimental evolution. Microbiology (Reading, England). 147: 995-1006. PMID 11283295 DOI: 10.1099/00221287-147-4-995  0.817
2001 Bronikowski AM, Bennett AF, Lenski RE. Evolutionary adaptation to temperature. VIII. Effects of temperature on growth rate in natural isolates of Escherichia coli and Salmonella enterica from different thermal environments. Evolution; International Journal of Organic Evolution. 55: 33-40. PMID 11263744 DOI: 10.1554/0014-3820(2001)055[0033:Eattve]2.0.Co;2  0.715
2001 Lenski R, Velicer GJ. Games Microbes Play Selection. 1: 89-96. DOI: 10.1556/Select.1.2000.1-3.9  0.774
2000 Bohannan BJM, Lenski RE. The Relative Importance of Competition and Predation Varies with Productivity in a Model Community. The American Naturalist. 156: 329-340. PMID 29592139 DOI: 10.1086/303393  0.723
2000 Cooper VS, Lenski RE. The population genetics of ecological specialization in evolving Escherichia coli populations. Nature. 407: 736-9. PMID 11048718 DOI: 10.1038/35037572  0.674
2000 Schneider D, Duperchy E, Coursange E, Lenski RE, Blot M. Long-term experimental evolution in Escherichia coli. IX. Characterization of insertion sequence-mediated mutations and rearrangements. Genetics. 156: 477-88. PMID 11014799  0.788
2000 Velicer GJ, Kroos L, Lenski RE. Developmental cheating in the social bacterium Myxococcus xanthus. Nature. 404: 598-601. PMID 10766241 DOI: 10.1038/35007066  0.794
2000 Moore FB, Rozen DE, Lenski RE. Pervasive compensatory adaptation in Escherichia coli. Proceedings. Biological Sciences / the Royal Society. 267: 515-22. PMID 10737410 DOI: 10.1098/Rspb.2000.1030  0.745
2000 Rozen DE, Lenski RE. Long-Term Experimental Evolution in Escherichia coli. VIII. Dynamics of a Balanced Polymorphism. The American Naturalist. 155: 24-35. PMID 10657174 DOI: 10.1086/303299  0.598
2000 Bohannan BJM, Lenski RE. The relative importance of competition and predation varies with productivity in a model community American Naturalist. 156: 329-340. DOI: 10.1086/303393  0.658
2000 Bohannan BJM, Lenski RE. Linking genetic change to community evolution: Insights from studies of bacteria and bacteriophage Ecology Letters. 3: 362-377. DOI: 10.1046/J.1461-0248.2000.00161.X  0.745
1999 Bohannan BJM, Lenski RE. Effect of Prey Heterogeneity on the Response of a Model Food Chain to Resource Enrichment. The American Naturalist. 153: 73-82. PMID 29578767 DOI: 10.1086/303151  0.72
1999 Mongold JA, Bennett AF, Lenski RE. EVOLUTIONARY ADAPTATION TO TEMPERATURE. VII. EXTENSION OF THE UPPER THERMAL LIMIT OF ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 53: 386-394. PMID 28565406 DOI: 10.1111/J.1558-5646.1999.Tb03774.X  0.803
1999 Bohannan BJM, Travisano M, Lenski RE. EPISTATIC INTERACTIONS CAN LOWER THE COST OF RESISTANCE TO MULTIPLE CONSUMERS. Evolution; International Journal of Organic Evolution. 53: 292-295. PMID 28565201 DOI: 10.1111/J.1558-5646.1999.Tb05355.X  0.782
1999 Velicer GJ, Schmidt TM, Lenski RE. Application of Traditional and Phylogenetically Based Comparative Methods to Test for a Trade-off in Bacterial Growth Rate at Low versus High Substrate Concentration. Microbial Ecology. 38: 191-200. PMID 10541781 DOI: 10.1007/S002489900169  0.776
1999 Lenski RE, Ofria C, Collier TC, Adami C. Genome complexity, robustness and genetic interactions in digital organisms. Nature. 400: 661-4. PMID 10458160 DOI: 10.1038/23245  0.828
1999 Vuli? M, Lenski RE, Radman M. Mutation, recombination, and incipient speciation of bacteria in the laboratory. Proceedings of the National Academy of Sciences of the United States of America. 96: 7348-51. PMID 10377417 DOI: 10.1073/Pnas.96.13.7348  0.4
1999 Papadopoulos D, Schneider D, Meier-Eiss J, Arber W, Lenski RE, Blot M. Genomic evolution during a 10,000-generation experiment with bacteria. Proceedings of the National Academy of Sciences of the United States of America. 96: 3807-12. PMID 10097119 DOI: 10.1073/Pnas.96.7.3807  0.836
1999 Arjan JA, Visser M, Zeyl CW, Gerrish PJ, Blanchard JL, Lenski RE. Diminishing returns from mutation supply rate in asexual populations. Science (New York, N.Y.). 283: 404-6. PMID 9888858 DOI: 10.1126/Science.283.5400.404  0.846
1999 Velicer GJ, Lenski RE. Evolutionary trade-offs under conditions of resource abundance and scarcity: Experiments with bacteria Ecology. 80: 1168-1179. DOI: 10.1890/0012-9658(1999)080[1168:Etouco]2.0.Co;2  0.796
1999 Benneir AF, Lenski RE. Experimental evolution and its role in evolutionary physiology American Zoologist. 39: 346-362. DOI: 10.1093/Icb/39.2.346  0.444
1999 BENNETT AF, LENSKI RE. Experimental Evolution and Its Role in Evolutionary Physiology American Zoologist. 39: 346-362. DOI: 10.1093/icb/39.2.346  0.505
1999 Bohannan BJM, Lenski RE. Effect of prey heterogeneity on the response of a model food chain to resource enrichment American Naturalist. 153: 73-82. DOI: 10.1086/303151  0.65
1999 Velicer G, Schmidt T, Lenski R. Application of Traditional and Phylogenetically Based Comparative Methods to Test for a Trade-off in Bacterial Growth Rate at Low versus High Substrate Concentration Microbial Ecology. 38: 191-200. DOI: 10.1007/s0024899001771999  0.578
1999 Vasi FK, Lenski RE. Ecological strategies and fitness tradeoffs in Escherichia coli mutants adapted to prolonged starvation Journal of Genetics. 78: 43-49. DOI: 10.1007/Bf02994702  0.392
1999 Mongold JA, Bennett AF, Lenski RE. Evolutionary adaptation to temperature. VII. Extension of the upper thermal limit of Escherichia coli Evolution. 53: 386-394.  0.763
1999 Bohannan BJM, Travisano M, Lenski RE. Epistatic interactions can lower the cost of resistance to multiple consumers Evolution. 53: 292-295.  0.743
1998 Turner PE, Cooper VS, Lenski RE. TRADEOFF BETWEEN HORIZONTAL AND VERTICAL MODES OF TRANSMISSION IN BACTERIAL PLASMIDS. Evolution; International Journal of Organic Evolution. 52: 315-329. PMID 28568337 DOI: 10.1111/J.1558-5646.1998.Tb01634.X  0.688
1998 Taylor DR, Jarosz AM, Fulbright DW, Lenski RE. The acquisition of hypovirulence in host-pathogen systems with three trophic levels. The American Naturalist. 151: 343-55. PMID 18811325 DOI: 10.1086/286123  0.757
1998 Moxon ER, Lenski RE, Rainey PB. Adaptive evolution of highly mutable loci in pathogenic bacteria. Perspectives in Biology and Medicine. 42: 154-5. PMID 10766604  0.564
1998 Velicer GJ, Kroos L, Lenski RE. Loss of social behaviors by myxococcus xanthus during evolution in an unstructured habitat. Proceedings of the National Academy of Sciences of the United States of America. 95: 12376-80. PMID 9770494 DOI: 10.1073/Pnas.95.21.12376  0.785
1998 Nakatsu CH, Korona R, Lenski RE, de Bruijn FJ, Marsh TL, Forney LJ. Parallel and divergent genotypic evolution in experimental populations of Ralstonia sp. Journal of Bacteriology. 180: 4325-31. PMID 9721265 DOI: 10.1128/Jb.180.17.4325-4331.1998  0.802
1998 Elena SF, Ekunwe L, Hajela N, Oden SA, Lenski RE. Distribution of fitness effects caused by random insertion mutations in Escherichia coli. Genetica. 102: 349-58. PMID 9720287 DOI: 10.1023/A:1017031008316  0.826
1998 Gerrish PJ, Lenski RE. The fate of competing beneficial mutations in an asexual population. Genetica. 102: 127-44. PMID 9720276 DOI: 10.1023/A:1017067816551  0.78
1998 Lenski RE, Mongold JA, Sniegowski PD, Travisano M, Vasi F, Gerrish PJ, Schmidt TM. Evolution of competitive fitness in experimental populations of E. coli: what makes one genotype a better competitor than another? Antonie Van Leeuwenhoek. 73: 35-47. PMID 9602277 DOI: 10.1023/A:1000675521611  0.834
1998 Turner PE, Cooper VS, Lenski RE. Tradeoff between horizontal and vertical modes of transmission in bacterial plasmids Evolution. 52: 315-329.  0.62
1997 Bennett AF, Lenski RE. EVOLUTIONARY ADAPTATION TO TEMPERATURE. VI. PHENOTYPIC ACCLIMATION AND ITS EVOLUTION IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 51: 36-44. PMID 28568801 DOI: 10.1111/J.1558-5646.1997.Tb02386.X  0.552
1997 Elena SF, Lenski RE. LONG-TERM EXPERIMENTAL EVOLUTION IN ESCHERICHIA COLI. VII. MECHANISMS MAINTAINING GENETIC VARIABILITY WITHIN POPULATIONS. Evolution; International Journal of Organic Evolution. 51: 1058-1067. PMID 28565475 DOI: 10.1111/J.1558-5646.1997.Tb03953.X  0.508
1997 Elena SF, Lenski RE. Test of synergistic interactions among deleterious mutations in bacteria. Nature. 390: 395-8. PMID 9389477 DOI: 10.1038/37108  0.453
1997 Bennett AF, Lenski RE. Phenotypic and evolutionary adaptation of a model bacterial system to stressful thermal environments. Exs. 83: 135-54. PMID 9342847  0.544
1997 Sniegowski PD, Gerrish PJ, Lenski RE. Evolution of high mutation rates in experimental populations of E. coli. Nature. 387: 703-5. PMID 9192894 DOI: 10.1038/42701  0.844
1997 Bohannan BJM, Lenski RE. Effect of resource enrichment on a chemostat community of bacteria and bacteriophage Ecology. 78: 2303-2315. DOI: 10.1890/0012-9658(1997)078[2303:Eoreoa]2.0.Co;2  0.742
1997 Souza V, Turner PE, Lenski RE. Long-term experimental evolution in Escherichia coli. V. Effects of recombination with immigrant genotypes on the rate of bacterial evolution Journal of Evolutionary Biology. 10: 743-769. DOI: 10.1046/J.1420-9101.1997.10050743.X  0.764
1997 Bennett AF, Lenski RE. Evolutionary adaptation to temperature. VI. Phenotypic acclimation and its evolution in Escherichia coli Evolution. 51: 36-44.  0.551
1996 Bennett AF, Lenski RE. EVOLUTIONARY ADAPTATION TO TEMPERATURE. V. ADAPTIVE MECHANISMS AND CORRELATED RESPONSES IN EXPERIMENTAL LINES OF ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 50: 493-503. PMID 28568929 DOI: 10.1111/J.1558-5646.1996.Tb03862.X  0.568
1996 Mongold JA, Bennett AF, Lenski RE. EVOLUTIONARY ADAPTATION TO TEMPERATURE. IV. ADAPTATION OF ESCHERICHIA COLI AT A NICHE BOUNDARY. Evolution; International Journal of Organic Evolution. 50: 35-43. PMID 28568880 DOI: 10.1111/J.1558-5646.1996.Tb04470.X  0.8
1996 Elena SF, Cooper VS, Lenski RE. Response: mechanisms of punctuated evolution. Science (New York, N.Y.). 274: 1749-50. PMID 17842245 DOI: 10.1126/Science.274.5293.1749  0.499
1996 Coyne JA, Charlesworth B, Elena SF, Cooper VS, Lenski RE. Mechanisms of punctuated evolution Science. 274: 1748-1750. PMID 8984635 DOI: 10.1126/Science.274.5293.1748  0.618
1996 Bonhoeffer S, Lenski RE, Ebert D. The curse of the pharaoh: the evolution of virulence in pathogens with long living propagules. Proceedings. Biological Sciences / the Royal Society. 263: 715-21. PMID 8763793 DOI: 10.1098/Rspb.1996.0107  0.72
1996 Mongold JA, Lenski RE. Experimental rejection of a nonadaptive explanation for increased cell size in Escherichia coli. Journal of Bacteriology. 178: 5333-4. PMID 8752359 DOI: 10.1128/Jb.178.17.5333-5334.1996  0.742
1996 Travisano M, Lenski RE. Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptation. Genetics. 143: 15-26. PMID 8722758  0.629
1996 Elena SF, Cooper VS, Lenski RE. Punctuated evolution caused by selection of rare beneficial mutations. Science (New York, N.Y.). 272: 1802-4. PMID 8650581 DOI: 10.1126/Science.272.5269.1802  0.675
1996 Turner PE, Souza V, Lenski RE. Tests of ecological mechanisms promoting the stable coexistence of two bacterial genotypes Ecology. 77: 2119-2129. DOI: 10.2307/2265706  0.706
1996 Bennett AF, Lenski RE. Evolutionary adaptation to temperature. V. Adaptive mechanisms and correlated responses in experimental lines of Escherichia coli Evolution. 50: 493-503.  0.505
1996 Mongold JA, Bennett AF, Lenski RE. Evolutionary adaptation to temperature. IV. Adaptation of Escherichia coli at a niche boundary Evolution. 50: 35-43.  0.769
1995 Travisano M, Vasi F, Lenski RE. LONG-TERM EXPERIMENTAL EVOLUTION IN ESCHERICHIA COLI. III. VARIATION AMONG REPLICATE POPULATIONS IN CORRELATED RESPONSES TO NOVEL ENVIRONMENTS. Evolution; International Journal of Organic Evolution. 49: 189-200. PMID 28593661 DOI: 10.1111/J.1558-5646.1995.Tb05970.X  0.831
1995 Travisano M, Mongold JA, Bennett AF, Lenski RE. Experimental tests of the roles of adaptation, chance, and history in evolution. Science (New York, N.Y.). 267: 87-90. PMID 7809610 DOI: 10.1126/Science.7809610  0.819
1995 Lenski RE, Sniegowski PD. Evolutionary genetics. Directed mutations slip-sliding away? Current Biology : Cb. 5: 97-9. PMID 7743184 DOI: 10.1016/S0960-9822(95)00023-6  0.735
1995 Lenski RE, Sniegowski PD. "Adaptive mutation": the debate goes on. Science (New York, N.Y.). 269: 285-8. PMID 7618089 DOI: 10.1126/Science.7618089  0.717
1995 Sniegowski PD, Lenski RE. Mutation and adaptation: The directed mutation controversy in evolutionary perspective Annual Review of Ecology and Systematics. 26: 553-578. DOI: 10.1146/Annurev.Es.26.110195.003005  0.731
1995 Johnson PA, Lenski RE, Hoppensteadt FC. Theoretical analysis of divergence in mean fitness between initially identical populations Proceedings of the Royal Society B: Biological Sciences. 259: 125-130. DOI: 10.1098/Rspb.1995.0019  0.69
1995 Travisano M, Vasi F, Lenski RE. Long-term experimental evolution in Escherichia coli. III. Variation among replicate populations in correlated responses to novel environments Evolution. 49: 189-200.  0.812
1994 Leroi AM, Lenski RE, Bennett AF. EVOLUTIONARY ADAPTATION TO TEMPERATURE. III. ADAPTATION OF ESCHERICHIA COLI TO A TEMPORALLY VARYING ENVIRONMENT. Evolution; International Journal of Organic Evolution. 48: 1222-1229. PMID 28564463 DOI: 10.1111/J.1558-5646.1994.Tb05307.X  0.671
1994 Lenski RE, Simpson SC, Nguyen TT. Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness. Journal of Bacteriology. 176: 3140-7. PMID 8195066 DOI: 10.1128/Jb.176.11.3140-3147.1994  0.592
1994 Leroi AM, Bennett AF, Lenski RE. Temperature acclimation and competitive fitness: an experimental test of the beneficial acclimation assumption. Proceedings of the National Academy of Sciences of the United States of America. 91: 1917-21. PMID 8127906 DOI: 10.1073/Pnas.91.5.1917  0.651
1994 Korona R, Nakatsu CH, Forney LJ, Lenski RE. Evidence for multiple adaptive peaks from populations of bacteria evolving in a structured habitat. Proceedings of the National Academy of Sciences of the United States of America. 91: 9037-41. PMID 8090765 DOI: 10.1073/Pnas.91.19.9037  0.787
1994 Lenski RE, Travisano M. Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations. Proceedings of the National Academy of Sciences of the United States of America. 91: 6808-14. PMID 8041701 DOI: 10.1073/Pnas.91.15.6808  0.735
1994 Lenski RE, Souza V, Duong LP, Phan QG, Nguyen TN, Bertrand KP. Epistatic effects of promoter and repressor functions of the Tn10 tetracycline-resistance operon of the fitness of Escherichia coli. Molecular Ecology. 3: 127-35. PMID 8019689 DOI: 10.1111/J.1365-294X.1994.Tb00113.X  0.545
1994 Lenski RE, May RM. The evolution of virulence in parasites and pathogens: reconciliation between two competing hypotheses. Journal of Theoretical Biology. 169: 253-65. PMID 7967617 DOI: 10.1006/Jtbi.1994.1146  0.518
1994 Moxon ER, Rainey PB, Nowak MA, Lenski RE. Adaptive evolution of highly mutable loci in pathogenic bacteria. Current Biology : Cb. 4: 24-33. PMID 7922307 DOI: 10.1016/S0960-9822(00)00005-1  0.73
1994 Vasi F, Travisano M, Lenski RE. Long-term experimental evolution in Escherichia coli. II.Changes in life-history traits during adaptation to a seasonal environment American Naturalist. 144: 432-456. DOI: 10.1086/285685  0.807
1994 Leroi AM, Lenski RE, Bennett AF. Evolutionary adaptation to temperature. III.Adaptation of Escherichia coli to a temporally varying environment Evolution. 48: 1222-1229.  0.658
1993 Bennett AF, Lenski RE. EVOLUTIONARY ADAPTATION TO TEMPERATURE II. THERMAL NICHES OF EXPERIMENTAL LINES OF ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 47: 1-12. PMID 28568084 DOI: 10.1111/J.1558-5646.1993.Tb01194.X  0.541
1993 Lenski RE, Bennett AF. Evolutionary response of escherichia coli to thermal stress. The American Naturalist. 142: S47-64. PMID 19425951 DOI: 10.1086/285522  0.546
1993 Lenski RE, Mittler JE. Response. Science (New York, N.Y.). 262: 318-9. PMID 17789902 DOI: 10.1126/science.262.5132.318  0.53
1993 Lenski RE, Mittler JE. Response. Science (New York, N.Y.). 260: 1222-4. PMID 17755405 DOI: 10.1126/science.260.5112.1222  0.53
1993 Lenski RE. Evolution: a lac of interest in evolution. Current Biology : Cb. 3: 121-3. PMID 15335810 DOI: 10.1016/0960-9822(93)90171-J  0.371
1993 Lenski RE. Assessing the genetic structure of microbial populations. Proceedings of the National Academy of Sciences of the United States of America. 90: 4334-6. PMID 8506269 DOI: 10.1073/Pnas.90.10.4334  0.426
1993 Lenski RE. Evaluating the fate of genetically modified microorganisms in the environment: are they inherently less fit? Experientia. 49: 201-9. PMID 8458406 DOI: 10.1007/Bf01923527  0.373
1993 Lenski RE, Mittler JE. The directed mutation controversy and neo-Darwinism. Science (New York, N.Y.). 259: 188-94. PMID 7678468 DOI: 10.1126/Science.7678468  0.722
1993 Lenski RE, Mittler JE. Whither directed mutation? [3] Science. 262: 318-319.  0.646
1993 Lenski RE, Mittler JE. Response [3] Science. 260: 1222-1224.  0.53
1993 Bennett AF, Lenski RE. Evolutionary adaptation to temperature. II. Thermal niches of experimental lines of Escherichia coli Evolution. 47: 1-12.  0.488
1992 Bennett AF, Lenski RE, Mittler JE. EVOLUTIONARY ADAPTATION TO TEMPERATURE. I. FITNESS RESPONSES OF ESCHERICHIA COLI TO CHANGES IN ITS THERMAL ENVIRONMENT. Evolution; International Journal of Organic Evolution. 46: 16-30. PMID 28564952 DOI: 10.1111/J.1558-5646.1992.Tb01981.X  0.712
1992 Mittler JE, Lenski RE. Experimental evidence for an alternative to directed mutation in the bgl operon. Nature. 356: 446-8. PMID 1557128 DOI: 10.1038/356446A0  0.709
1992 Souza V, Nguyen TT, Hudson RR, Piñero D, Lenski RE. Hierarchical analysis of linkage disequilibrium in Rhizobium populations: evidence for sex? Proceedings of the National Academy of Sciences of the United States of America. 89: 8389-93. PMID 1518873 DOI: 10.1073/Pnas.89.17.8389  0.772
1992 Bennett AF, Lenski RE, Mittler JE. Evolutionary adaptation to temperature. I. Fitness responses of Escherichia coli to changes in its thermal environment Evolution. 46: 16-30.  0.708
1991 Lenski RE. Quantifying fitness and gene stability in microorganisms. Biotechnology (Reading, Mass.). 15: 173-92. PMID 2009380 DOI: 10.1016/B978-0-409-90199-3.50015-2  0.396
1991 Lenski RE, Rose MR, Simpson SC, Tadler SC. Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2000 generations American Naturalist. 138: 1315-1341. DOI: 10.1086/285289  0.59
1990 Mittler JE, Lenski RE. New data on excisions of Mu from E. coli MCS2 cast doubt on directed mutation hypothesis. Nature. 344: 173-5. PMID 2407962 DOI: 10.1038/344173A0  0.717
1990 Bennett AF, Dao KM, Lenski RE. Rapid evolution in response to high-temperature selection. Nature. 346: 79-81. PMID 2195353 DOI: 10.1038/346079A0  0.651
1990 Mittler JE, Lenski R. Causes of mutation and Mu excision Nature. 345: 213-213. DOI: 10.1038/345213B0  0.673
1990 Mittler JE, Lenski RE. Causes of mutation and Mu excision [11] Nature. 345: 213.  0.642
1989 Lenski RE. Are some mutations directed? Trends in Ecology & Evolution. 4: 148-50. PMID 21227341 DOI: 10.1016/0169-5347(89)90218-8  0.458
1989 Lenski RE, Slatkin M, Ayala FJ. Mutation and selection in bacterial populations: alternatives to the hypothesis of directed mutation. Proceedings of the National Academy of Sciences of the United States of America. 86: 2775-8. PMID 2704747 DOI: 10.1073/Pnas.86.8.2775  0.719
1989 Lenski RE, Slatkin M, Ayala FJ. Another alternative to directed mutation. Nature. 337: 123-4. PMID 2643054 DOI: 10.1038/337123B0  0.669
1989 Tiedje JM, Colwell RK, Grossman YL, Hodson RE, Lenski RE, Mack RN, Regal PJ. The Planned Introduction of Genetically Engineered Organisms: Ecological Considerations and Recommendations Ecology. 70: 298-315. DOI: 10.2307/1937535  0.52
1988 Lenski RE. EXPERIMENTAL STUDIES OF PLEIOTROPY AND EPISTASIS IN ESCHERICHIA COLI. II. COMPENSATION FOR MALADAPTIVE EFFECTS ASSOCIATED WITH RESISTANCE TO VIRUS T4. Evolution; International Journal of Organic Evolution. 42: 433-440. PMID 28564011 DOI: 10.1111/J.1558-5646.1988.Tb04150.X  0.44
1988 Lenski RE. EXPERIMENTAL STUDIES OF PLEIOTROPY AND EPISTASIS IN ESCHERICHIA COLI. I. VARIATION IN COMPETITIVE FITNESS AMONG MUTANTS RESISTANT TO VIRUS T4. Evolution; International Journal of Organic Evolution. 42: 425-432. PMID 28564005 DOI: 10.1111/J.1558-5646.1988.Tb04149.X  0.381
1988 Lenski RE, Nguyen TT. Stability of recombinant DNA and its effects on fitness. Trends in Ecology & Evolution. 3: S18-20. PMID 21227121 DOI: 10.1016/0167-7799(88)90008-X  0.534
1988 Lenski RE. Evolution of plague virulence. Nature. 334: 473-4. PMID 3405295 DOI: 10.1038/334473A0  0.323
1988 Bouma JE, Lenski RE. Evolution of a bacteria/plasmid association. Nature. 335: 351-2. PMID 3047585 DOI: 10.1038/335351A0  0.637
1987 Lenski RE, Bouma JE. Effects of segregation and selection on instability of plasmid pACYC184 in Escherichia coli B. Journal of Bacteriology. 169: 5314-6. PMID 3312174 DOI: 10.1128/Jb.169.11.5314-5316.1987  0.614
1985 Lenski RE, Levin BR. Constraints on the coevolution of bacteria and virulent phage: a model, some experiments, and predictions for natural communities American Naturalist. 125: 585-602. DOI: 10.1086/284364  0.637
1984 Lenski RE. Coevolution of bacteria and phage: are there endless cycles of bacterial defenses and phage counterdefenses? Journal of Theoretical Biology. 108: 319-25. PMID 6748694 DOI: 10.1016/S0022-5193(84)80035-1  0.33
1982 Service PM, Lenski RE. APHID GENOTYPES, PLANT PHENOTYPES, AND GENETIC DIVERSITY: A DEMOGRAPHIC ANALYSIS OF EXPERIMENTAL DATA. Evolution; International Journal of Organic Evolution. 36: 1276-1282. PMID 28563557 DOI: 10.1111/J.1558-5646.1982.Tb05496.X  0.766
1982 Lenski RE, Service PM. The Statistical Analysis of Population Growth Rates Calculated from Schedules of Survivorship and Fecunidity Ecology. 63: 655-662. DOI: 10.2307/1936785  0.356
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