Vadim N. Gladyshev - Publications

Affiliations: 
1998-2009 Biochemistry The University of Nebraska - Lincoln, Lincoln, NE 
 2009- Brigham, and Women’s Hospital Harvard Medical School, Boston, MA, United States 
Area:
redox biology and trace elements as applied to cancer, aging and male reproduction
Website:
https://lifeboat.com/ex/bios.vadim.n.gladyshev

321 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yim SH, Clish CB, Gladyshev VN. Selenium Deficiency Is Associated with Pro-longevity Mechanisms. Cell Reports. 27: 2785-2797.e3. PMID 31141699 DOI: 10.1016/j.celrep.2019.05.001  0.32
2019 Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, ... ... Gladyshev VN, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 177: 622-638.e22. PMID 31002797 DOI: 10.1016/j.cell.2019.03.043  0.48
2019 Mariotti M, Salinas G, Gabaldón T, Gladyshev VN. Utilization of selenocysteine in early-branching fungal phyla. Nature Microbiology. PMID 30742068 DOI: 10.1038/s41564-018-0354-9  0.48
2019 O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, et al. Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. Plos Genetics. 15: e1007917. PMID 30707697 DOI: 10.1371/journal.pgen.1007917  0.96
2018 Meer MV, Podolskiy DI, Tyshkovskiy A, Gladyshev VN. A whole lifespan mouse multi-tissue DNA methylation clock. Elife. 7. PMID 30427307 DOI: 10.7554/eLife.40675  0.44
2018 Lee SG, Mikhalchenko AE, Yim SH, Gladyshev VN. A naked mole rat iPSC line expressing drug-inducible mouse pluripotency factors developed from embryonic fibroblasts. Stem Cell Research. 31: 197-200. PMID 30107334 DOI: 10.1016/j.scr.2018.06.010  0.32
2018 Zhang Y, Lee JH, Paull TT, Gehrke S, D'Alessandro A, Dou Q, Gladyshev VN, Schroeder EA, Steyl SK, Christian BE, Shadel GS. Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity. Science Signaling. 11. PMID 29991649 DOI: 10.1126/scisignal.aaq0702  0.76
2018 Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, ... ... Gladyshev VN, et al. NEDD9 targets to promote endothelial fibrosis and pulmonary arterial hypertension. Science Translational Medicine. 10. PMID 29899023 DOI: 10.1126/scitranslmed.aap7294  0.56
2018 Peters KM, Carlson BA, Gladyshev VN, Tsuji PA. "Selenoproteins in colon cancer". Free Radical Biology & Medicine. PMID 29793041 DOI: 10.1016/j.freeradbiomed.2018.05.075  0.88
2018 Yim SH, Everley RA, Schildberg FA, Lee SG, Orsi A, Barbati ZR, Karatepe K, Fomenko DE, Tsuji PA, Luo HR, Gygi SP, Sitia R, Sharpe AH, Hatfield DL, Gladyshev VN. Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins. Cell Reports. 23: 1387-1398. PMID 29719252 DOI: 10.1016/j.celrep.2018.04.009  0.88
2018 Na J, Jung J, Bang J, Lu Q, Carlson BA, Guo X, Gladyshev VN, Kim J, Hatfield DL, Lee BJ. Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation. Free Radical Biology & Medicine. PMID 29715549 DOI: 10.1016/j.freeradbiomed.2018.04.577  0.88
2018 Ma S, Avanesov AS, Porter E, Lee BC, Mariotti M, Zemskaya N, Guigo R, Moskalev AA, Gladyshev VN. Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. Aging Cell. e12740. PMID 29671950 DOI: 10.1111/acel.12740  0.64
2018 Zhou X, Guang X, Sun D, Xu S, Li M, Seim I, Jie W, Yang L, Zhu Q, Xu J, Gao Q, Kaya A, Dou Q, Chen B, Ren W, ... ... Gladyshev VN, et al. Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater. Nature Communications. 9: 1276. PMID 29636446 DOI: 10.1038/s41467-018-03722-x  0.68
2018 Zhou X, Sun D, Guang X, Ma S, Fang X, Mariotti M, Nielsen R, Gladyshev VN, Yang G. Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans. Genome Biology and Evolution. 10: 967-975. PMID 29608729 DOI: 10.1093/gbe/evy062  0.48
2018 Lee BC, Lee HM, Kim S, Avanesov AS, Lee A, Chun BH, Vorbruggen G, Gladyshev VN. Expression of the methionine sulfoxide reductase lost during evolution extends Drosophila lifespan in a methionine-dependent manner. Scientific Reports. 8: 1010. PMID 29343716 DOI: 10.1038/s41598-017-15090-5  0.64
2018 Yordanova MM, Loughran G, Zhdanov AV, Mariotti M, Kiniry SJ, O'Connor PBF, Andreev DE, Tzani I, Saffert P, Michel AM, Gladyshev VN, Papkovsky DB, Atkins JF, Baranov PV. AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation. Nature. PMID 29310120 DOI: 10.1038/nature25174  0.48
2018 Tarrago L, Oheix E, Péterfi Z, Gladyshev VN. Monitoring of Methionine Sulfoxide Content and Methionine Sulfoxide Reductase Activity. Methods in Molecular Biology (Clifton, N.J.). 1661: 285-299. PMID 28917052 DOI: 10.1007/978-1-4939-7258-6_20  0.4
2018 Carlson BA, Lee BJ, Tsuji PA, Copeland PR, Schweizer U, Gladyshev VN, Hatfield DL. Selenocysteine tRNA([Ser]Sec), the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1661: 43-60. PMID 28917036 DOI: 10.1007/978-1-4939-7258-6_4  0.88
2017 Lee SG, Mikhalchenko AE, Yim SH, Lobanov AV, Park JK, Choi KH, Bronson RT, Lee CK, Park TJ, Gladyshev VN. Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. Stem Cell Reports. PMID 29107591 DOI: 10.1016/j.stemcr.2017.09.013  0.68
2017 Ma S, Gladyshev VN. Molecular signatures of longevity: insights from cross-species comparative studies. Seminars in Cell & Developmental Biology. PMID 28800931 DOI: 10.1016/j.semcdb.2017.08.007  0.32
2017 Kaya A, Mariotti M, Gladyshev VN. Cytochrome c peroxidase facilitates the beneficial use of H2O2 in prokaryotes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28765365 DOI: 10.1073/pnas.1710943114  0.68
2017 Lee BC, Lee SG, Choo MK, Kim JH, Lee HM, Kim S, Fomenko DE, Kim HY, Park JM, Gladyshev VN. Selenoprotein MsrB1 promotes anti-inflammatory cytokine gene expression in macrophages and controls immune response in vivo. Scientific Reports. 7: 5119. PMID 28698597 DOI: 10.1038/s41598-017-05230-2  0.64
2017 Renko K, Martitz J, Hybsier S, Heynisch B, Voss L, Everley RA, Gygi SP, Stoedter M, Wisniewska M, Köhrle J, Gladyshev VN, Schomburg L. Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P. Scientific Reports. 7: 4391. PMID 28663583 DOI: 10.1038/s41598-017-04586-9  0.44
2017 Salinas G, Gao W, Wang Y, Bonilla M, Yu L, Novikov A, Virginio VG, Ferreira H, Vieites M, Gladyshev VN, Gambino D, Dai S. The enzymatic and structural basis for inhibition of Echinococcus granulosus thioredoxin glutathione reductase by gold(I). Antioxidants & Redox Signaling. PMID 28463568 DOI: 10.1089/ars.2016.6816  0.36
2017 Petkovich DA, Podolskiy DI, Lobanov AV, Lee SG, Miller RA, Gladyshev VN. Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions. Cell Metabolism. 25: 954-960.e6. PMID 28380383 DOI: 10.1016/j.cmet.2017.03.016  0.68
2017 Lee SG, Kaya A, Avanesov AS, Podolskiy DI, Song EJ, Go DM, Jin GD, Hwang JY, Kim EB, Kim DY, Gladyshev VN. Age-associated molecular changes are deleterious and may modulate life span through diet. Science Advances. 3: e1601833. PMID 28232953 DOI: 10.1126/sciadv.1601833  0.68
2017 Payne NC, Geissler A, Button A, Sasuclark AR, Schroll AL, Ruggles EL, Gladyshev VN, Hondal RJ. Comparison of the redox chemistry of sulfur- and selenium-containing analogs of uracil. Free Radical Biology & Medicine. PMID 28108278 DOI: 10.1016/j.freeradbiomed.2017.01.028  0.44
2016 Seim I, Ma S, Gladyshev VN. Gene expression signatures of human cell and tissue longevity. Npj Aging and Mechanisms of Disease. 2: 16014. PMID 28721269 DOI: 10.1038/npjamd.2016.14  0.32
2016 Ma S, Upneja A, Galecki A, Tsai YM, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN. Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. Elife. 5. PMID 27874830 DOI: 10.7554/eLife.19130  0.32
2016 Lobanov AV, Heaphy SM, Turanov AA, Gerashchenko MV, Pucciarelli S, Devaraj RR, Xie F, Petyuk VA, Smith RD, Klobutcher LA, Atkins JF, Miceli C, Hatfield DL, Baranov PV, Gladyshev VN. Position-dependent termination and widespread obligatory frameshifting in Euplotes translation. Nature Structural & Molecular Biology. PMID 27870834 DOI: 10.1038/nsmb.3330  1
2016 Li M, Chen L, Tian S, Lin Y, Tang Q, Zhou X, Li D, Yeung CK, Che T, Jin L, Fu Y, Ma J, Wang X, Jiang A, Lan J, ... ... Gladyshev VN, et al. Comprehensive variation discovery and recovery of missing sequence in the pig genome using multiple de novo assemblies. Genome Research. PMID 27646534 DOI: 10.1101/gr.207456.116  0.64
2016 Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, et al. Selenoprotein Gene Nomenclature. The Journal of Biological Chemistry. PMID 27645994 DOI: 10.1074/jbc.M116.756155  0.88
2016 Gerashchenko MV, Gladyshev VN. Ribonuclease selection for ribosome profiling. Nucleic Acids Research. PMID 27638886 DOI: 10.1093/nar/gkw822  0.96
2016 Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, ... ... Gladyshev VN, et al. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588899 DOI: 10.1073/pnas.1600204113  1
2016 Podolskiy DI, Gladyshev VN. Intrinsic Versus Extrinsic Cancer Risk Factors and Aging. Trends in Molecular Medicine. PMID 27544777 DOI: 10.1016/j.molmed.2016.08.001  0.44
2016 Podolskiy DI, Lobanov AV, Kryukov GV, Gladyshev VN. Analysis of cancer genomes reveals basic features of human aging and its role in cancer development. Nature Communications. 7: 12157. PMID 27515585 DOI: 10.1038/ncomms12157  0.72
2016 Heaphy SM, Mariotti M, Gladyshev VN, Atkins JF, Baranov PV. Novel ciliate genetic code variants including the reassignment of all three stop codons to sense codons in C. magnum. Molecular Biology and Evolution. PMID 27501944 DOI: 10.1093/molbev/msw166  0.48
2016 Mariotti M, Lobanov AV, Manta B, Santesmasses D, Bofill A, Guigó R, Gabaldón T, Gladyshev VN. Lokiarchaeota marks the transition between the archaeal and eukaryotic selenocysteine encoding systems. Molecular Biology and Evolution. PMID 27413050 DOI: 10.1093/molbev/msw122  0.68
2016 Peterfi Z, Tarrago L, Gladyshev VN. Practical guide for dynamic monitoring of protein oxidation using genetically encoded ratiometric fluorescent bioensors of methionine sulfoxide. Methods (San Diego, Calif.). PMID 27345570 DOI: 10.1016/j.ymeth.2016.06.022  0.4
2016 Carlson BA, Tobe R, Yefremova E, Tsuji PA, Hoffmann VJ, Schweizer U, Gladyshev VN, Hatfield DL, Conrad M. Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration. Redox Biology. 9: 22-31. PMID 27262435 DOI: 10.1016/j.redox.2016.05.003  0.88
2016 Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, ... ... Gladyshev VN, et al. Selenophosphate Synthetase 1 is an Essential Protein with Roles in Regulation of Redox Homeostasis in Mammals. The Biochemical Journal. PMID 27208177 DOI: 10.1042/BCJ20160393  0.88
2016 Gladyshev VN. Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes. Aging Cell. PMID 27060562 DOI: 10.1111/acel.12480  1
2015 Kaya A, Ma S, Wasko B, Lee M, Kaeberlein M, Gladyshev VN. Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. Npj Aging and Mechanisms of Disease. 1. PMID 27030810 DOI: 10.1038/npjamd.2015.1  0.68
2015 Lee BC, Kaya A, Gladyshev VN. Methionine restriction and life-span control. Annals of the New York Academy of Sciences. PMID 26663138 DOI: 10.1111/nyas.12973  1
2015 Tobe R, Carlson BA, Tsuji PA, Lee BJ, Gladyshev VN, Hatfield DL. Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy. Cancers. 7: 2262-76. PMID 26569310 DOI: 10.3390/cancers7040889  1
2015 Zhou X, Seim I, Gladyshev VN. Convergent evolution of marine mammals is associated with distinct substitutions in common genes. Scientific Reports. 5: 16550. PMID 26549748 DOI: 10.1038/srep16550  1
2015 Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN. Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. Cell Reports. PMID 26549444 DOI: 10.1016/j.celrep.2015.10.014  1
2015 Turanov AA, Everley RA, Hybsier S, Renko K, Schomburg L, Gygi SP, Hatfield DL, Gladyshev VN. Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine. Plos One. 10: e0140353. PMID 26452064 DOI: 10.1371/journal.pone.0140353  1
2015 Bisio H, Bonilla M, Manta B, Graña M, Salzman V, Aguilar PS, Gladyshev VN, Comini MA, Salinas G. A New Class of Thioredoxin-Related Protein Able to Bind Iron-Sulfur Clusters. Antioxidants & Redox Signaling. PMID 26381228 DOI: 10.1089/ars.2015.6377  0.36
2015 Kaya A, Gerashchenko MV, Seim I, Labarre J, Toledano MB, Gladyshev VN. Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins. Proceedings of the National Academy of Sciences of the United States of America. 112: 10685-90. PMID 26261310 DOI: 10.1073/pnas.1505315112  1
2015 Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN. Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity. Cell Metabolism. 22: 332-43. PMID 26244935 DOI: 10.1016/j.cmet.2015.07.005  1
2015 Mariotti M, Santesmasses D, Capella-Gutierrez S, Mateo A, Arnan C, Johnson R, D'Aniello S, Yim SH, Gladyshev VN, Serras F, Corominas M, Gabaldón T, Guigó R. Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization. Genome Research. 25: 1256-67. PMID 26194102 DOI: 10.1101/gr.190538.115  1
2015 Kaya A, Lee BC, Gladyshev VN. Regulation of Protein Function by Reversible Methionine Oxidation and the Role of Selenoprotein MsrB1. Antioxidants & Redox Signaling. 23: 814-22. PMID 26181576 DOI: 10.1089/ars.2015.6385  1
2015 Gould NS, Evans P, Martínez-Acedo P, Marino SM, Gladyshev VN, Carroll KS, Ischiropoulos H. Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks. Chemistry & Biology. 22: 965-75. PMID 26165157 DOI: 10.1016/j.chembiol.2015.06.010  1
2015 Kim MJ, Lee BC, Hwang KY, Gladyshev VN, Kim HY. Selenium utilization in thioredoxin and catalytic advantage provided by selenocysteine. Biochemical and Biophysical Research Communications. 461: 648-52. PMID 25912135 DOI: 10.1016/j.bbrc.2015.04.082  1
2015 Tsuji PA, Carlson BA, Yoo MH, Naranjo-Suarez S, Xu XM, He Y, Asaki E, Seifried HE, Reinhold WC, Davis CD, Gladyshev VN, Hatfield DL. The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways. Plos One. 10: e0124487. PMID 25886253 DOI: 10.1371/journal.pone.0124487  1
2015 Tarrago L, Péterfi Z, Lee BC, Michel T, Gladyshev VN. Monitoring methionine sulfoxide with stereospecific mechanism-based fluorescent sensors. Nature Chemical Biology. 11: 332-8. PMID 25799144 DOI: 10.1038/nchembio.1787  0.64
2015 Bang J, Huh JH, Na JW, Lu Q, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ. Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells. Molecules and Cells. 38: 457-65. PMID 25728752 DOI: 10.14348/molcells.2015.0007  1
2015 Kaya A, Lobanov AV, Gladyshev VN. Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae. Aging Cell. 14: 366-71. PMID 25702753 DOI: 10.1111/acel.12290  0.68
2015 Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN. Gene expression defines natural changes in mammalian lifespan. Aging Cell. 14: 352-65. PMID 25677554 DOI: 10.1111/acel.12283  1
2015 Nakao LS, Everley RA, Marino SM, Lo SM, de Souza LE, Gygi SP, Gladyshev VN. Mechanism-based proteomic screening identifies targets of thioredoxin-like proteins. The Journal of Biological Chemistry. 290: 5685-95. PMID 25561728 DOI: 10.1074/jbc.M114.597245  1
2015 Hine C, Harputlugil E, Zhang Y, Ruckenstuhl C, Lee BC, Brace L, Longchamp A, Treviño-Villarreal JH, Mejia P, Ozaki CK, Wang R, Gladyshev VN, Madeo F, Mair WB, Mitchell JR. Endogenous hydrogen sulfide production is essential for dietary restriction benefits. Cell. 160: 132-44. PMID 25542313 DOI: 10.1016/j.cell.2014.11.048  1
2015 Bang J, Jang M, Huh JH, Na JW, Shim M, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ. Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. Biochemical and Biophysical Research Communications. 456: 884-90. PMID 25529450 DOI: 10.1016/j.bbrc.2014.12.059  1
2015 Cornelis MC, Fornage M, Foy M, Xun P, Gladyshev VN, Morris S, Chasman DI, Hu FB, Rimm EB, Kraft P, Jordan JM, Mozaffarian D, He K. Genome-wide association study of selenium concentrations. Human Molecular Genetics. 24: 1469-77. PMID 25343990 DOI: 10.1093/hmg/ddu546  1
2015 Kaya A, Lobanov AV, Gladyshev VN. Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae Aging Cell. 14: 366-371. DOI: 10.1111/acel.12290  1
2014 Gladyshev VN. Selenium and Methionine Sulfoxide Reduction. Free Radical Biology & Medicine. 75: S8-9. PMID 26461418 DOI: 10.1016/j.freeradbiomed.2014.10.848  1
2014 Seim I, Ma S, Zhou X, Gerashchenko MV, Lee SG, Suydam R, George JC, Bickham JW, Gladyshev VN. The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. Aging. 6: 879-99. PMID 25411232  0.96
2014 Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, ... ... Gladyshev VN, et al. Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. Cell Reports. 8: 1354-64. PMID 25176646 DOI: 10.1016/j.celrep.2014.07.030  1
2014 Kaya A, Lobanov AV, Gerashchenko MV, Koren A, Fomenko DE, Koc A, Gladyshev VN. Thiol peroxidase deficiency leads to increased mutational load and decreased fitness in Saccharomyces cerevisiae. Genetics. 198: 905-17. PMID 25173844 DOI: 10.1534/genetics.114.169243  1
2014 Gerashchenko MV, Gladyshev VN. Translation inhibitors cause abnormalities in ribosome profiling experiments. Nucleic Acids Research. 42: e134. PMID 25056308 DOI: 10.1093/nar/gku671  1
2014 Guo C, Chen X, Song H, Maynard MA, Zhou Y, Lobanov AV, Gladyshev VN, Ganis JJ, Wiley D, Jugo RH, Lee NY, Castroneves LA, Zon LI, Scanlan TS, Feldman HA, et al. Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology. 155: 4069-80. PMID 25004091 DOI: 10.1210/en.2013-2029  1
2014 Labunskyy VM, Hatfield DL, Gladyshev VN. Selenoproteins: molecular pathways and physiological roles. Physiological Reviews. 94: 739-77. PMID 24987004 DOI: 10.1152/physrev.00039.2013  1
2014 Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nature Reviews. Genetics. 15: 531-40. PMID 24981598 DOI: 10.1038/nrg3728  1
2014 Turanov AA, Shchedrina VA, Everley RA, Lobanov AV, Yim SH, Marino SM, Gygi SP, Hatfield DL, Gladyshev VN. Selenoprotein S is involved in maintenance and transport of multiprotein complexes. The Biochemical Journal. 462: 555-65. PMID 24897171 DOI: 10.1042/BJ20140076  1
2014 Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N. The first international mini-symposium on methionine restriction and lifespan. Frontiers in Genetics. 5: 122. PMID 24847356 DOI: 10.3389/fgene.2014.00122  1
2014 Avanesov AS, Ma S, Pierce KA, Yim SH, Lee BC, Clish CB, Gladyshev VN. Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation. Elife. 3: e02077. PMID 24843015 DOI: 10.7554/eLife.02077  1
2014 Otero L, Romanelli-Cedrez L, Turanov AA, Gladyshev VN, Miranda-Vizuete A, Salinas G. Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage. Rna (New York, N.Y.). 20: 1023-34. PMID 24817701 DOI: 10.1261/rna.043877.113  1
2014 Labunskyy VM, Suzuki Y, Hanly TJ, Murao A, Roth FP, Gladyshev VN. The insertion Green Monster (iGM) method for expression of multiple exogenous genes in yeast. G3 (Bethesda, Md.). 4: 1183-91. PMID 24776987 DOI: 10.1534/g3.114.010868  0.96
2014 Han SJ, Lee BC, Yim SH, Gladyshev VN, Lee SR. Characterization of mammalian selenoprotein o: a redox-active mitochondrial protein. Plos One. 9: e95518. PMID 24751718 DOI: 10.1371/journal.pone.0095518  1
2014 Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE. Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression. The Journal of Biological Chemistry. 289: 15350-62. PMID 24719327 DOI: 10.1074/jbc.M114.549782  1
2014 Lee BC, Kaya A, Ma S, Kim G, Gerashchenko MV, Yim SH, Hu Z, Harshman LG, Gladyshev VN. Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status. Nature Communications. 5: 3592. PMID 24710037 DOI: 10.1038/ncomms4592  1
2014 Malinouski M, Hasan NM, Zhang Y, Seravalli J, Lin J, Avanesov A, Lutsenko S, Gladyshev VN. Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism. Nature Communications. 5: 3301. PMID 24522796 DOI: 10.1038/ncomms4301  1
2014 Hatfield DL, Tsuji PA, Carlson BA, Gladyshev VN. Selenium and selenocysteine: roles in cancer, health, and development. Trends in Biochemical Sciences. 39: 112-20. PMID 24485058 DOI: 10.1016/j.tibs.2013.12.007  1
2014 Labunskyy VM, Gerashchenko MV, Delaney JR, Kaya A, Kennedy BK, Kaeberlein M, Gladyshev VN. Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. Plos Genetics. 10: e1004019. PMID 24391512 DOI: 10.1371/journal.pgen.1004019  1
2014 Romagné F, Santesmasses D, White L, Sarangi GK, Mariotti M, Hübler R, Weihmann A, Parra G, Gladyshev VN, Guigó R, Castellano S. SelenoDB 2.0: annotation of selenoprotein genes in animals and their genetic diversity in humans. Nucleic Acids Research. 42: D437-43. PMID 24194593 DOI: 10.1093/nar/gkt1045  1
2014 Gladyshev VN. The free radical theory of aging is dead. Long live the damage theory! Antioxidants & Redox Signaling. 20: 727-31. PMID 24159899 DOI: 10.1089/ars.2013.5228  1
2013 Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL. Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus. Plos One. 8: e71427. PMID 24039713 DOI: 10.1371/journal.pone.0071427  1
2013 Seim I, Fang X, Xiong Z, Lobanov AV, Huang Z, Ma S, Feng Y, Turanov AA, Zhu Y, Lenz TL, Gerashchenko MV, Fan D, Hee Yim S, Yao X, Jordan D, ... ... Gladyshev VN, et al. Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. Nature Communications. 4: 2212. PMID 23962925 DOI: 10.1038/ncomms3212  1
2013 Naranjo-Suarez S, Carlson BA, Tobe R, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL. Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status. Molecules and Cells. 36: 151-7. PMID 23912593 DOI: 10.1007/s10059-013-0121-y  1
2013 Lee BC, Péterfi Z, Hoffmann FW, Moore RE, Kaya A, Avanesov A, Tarrago L, Zhou Y, Weerapana E, Fomenko DE, Hoffmann PR, Gladyshev VN. MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Molecular Cell. 51: 397-404. PMID 23911929 DOI: 10.1016/j.molcel.2013.06.019  1
2013 Mariotti M, Lobanov AV, Guigo R, Gladyshev VN. SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins. Nucleic Acids Research. 41: e149. PMID 23783574 DOI: 10.1093/nar/gkt550  1
2013 Le DT, Tarrago L, Watanabe Y, Kaya A, Lee BC, Tran U, Nishiyama R, Fomenko DE, Gladyshev VN, Tran LS. Diversity of plant methionine sulfoxide reductases B and evolution of a form specific for free methionine sulfoxide. Plos One. 8: e65637. PMID 23776515 DOI: 10.1371/journal.pone.0065637  1
2013 Gladyshev VN. The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan. Trends in Genetics : Tig. 29: 506-12. PMID 23769208 DOI: 10.1016/j.tig.2013.05.004  1
2013 Turanov AA, Lobanov AV, Hatfield DL, Gladyshev VN. UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins. Nucleic Acids Research. 41: 6952-9. PMID 23716634 DOI: 10.1093/nar/gkt409  1
2013 Gladyshev VN, Zhang Y. Comparative genomics analysis of the metallomes. Metal Ions in Life Sciences. 12: 529-80. PMID 23595683 DOI: 10.1007/978-94-007-5561-1_16  1
2013 Tobe R, Naranjo-Suarez S, Everley RA, Carlson BA, Turanov AA, Tsuji PA, Yoo MH, Gygi SP, Gladyshev VN, Hatfield DL. High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin. The Journal of Biological Chemistry. 288: 14709-15. PMID 23589299 DOI: 10.1074/jbc.M112.446666  1
2013 Gobler CJ, Lobanov AV, Tang YZ, Turanov AA, Zhang Y, Doblin M, Taylor GT, Sañudo-Wilhelmy SA, Grigoriev IV, Gladyshev VN. The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens. The Isme Journal. 7: 1333-43. PMID 23466703 DOI: 10.1038/ismej.2013.25  1
2013 Moustafa ME, Carlson BA, Anver MR, Bobe G, Zhong N, Ward JM, Perella CM, Hoffmann VJ, Rogers K, Combs GF, Schweizer U, Merlino G, Gladyshev VN, Hatfield DL. Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα. Plos One. 8: e57389. PMID 23460847 DOI: 10.1371/journal.pone.0057389  1
2013 Kasaikina MV, Turanov AA, Avanesov A, Schweizer U, Seeher S, Bronson RT, Novoselov SN, Carlson BA, Hatfield DL, Gladyshev VN. Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis. Carcinogenesis. 34: 1089-95. PMID 23389288 DOI: 10.1093/carcin/bgt011  1
2013 Hondal RJ, Marino SM, Gladyshev VN. Selenocysteine in thiol/disulfide-like exchange reactions. Antioxidants & Redox Signaling. 18: 1675-89. PMID 23121622 DOI: 10.1089/ars.2012.5013  1
2013 Williams DL, Bonilla M, Gladyshev VN, Salinas G. Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites. Antioxidants & Redox Signaling. 19: 735-45. PMID 22909029 DOI: 10.1089/ars.2012.4670  1
2013 Labunskyy VM, Gladyshev VN. Role of reactive oxygen species-mediated signaling in aging. Antioxidants & Redox Signaling. 19: 1362-72. PMID 22901002 DOI: 10.1089/ars.2012.4891  1
2013 Marino SM, Roos G, Gladyshev VN. Computational redox biology: Methods and applications Oxidative Stress and Redox Regulation. 2147483647: 187-211. DOI: 10.1007/978-94-007-5787-5_7  1
2013 Lobanov AV, Gladyshev VN. Selenoproteome of Kinetoplastids Trypanosomatid Diseases: Molecular Routes to Drug Discovery. 237-242. DOI: 10.1002/9783527670383.ch12  1
2012 Dobrovolska O, Shumilina E, Gladyshev VN, Dikiy A. Structural analysis of glutaredoxin domain of Mus musculus thioredoxin glutathione reductase. Plos One. 7: e52914. PMID 23300818 DOI: 10.1371/journal.pone.0052914  1
2012 Tsuji PA, Carlson BA, Naranjo-Suarez S, Yoo MH, Xu XM, Fomenko DE, Gladyshev VN, Hatfield DL, Davis CD. Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice. Plos One. 7: e50574. PMID 23226526 DOI: 10.1371/journal.pone.0050574  1
2012 Tarrago L, Gladyshev VN. Recharging oxidative protein repair: Catalysis by methionine sulfoxide reductases towards their amino acid, protein substrates model Biochemistry (Moscow). 77: 1097-1107. PMID 23157290 DOI: 10.1134/S0006297912100021  1
2012 Liang X, Kaya A, Zhang Y, Le DT, Hua D, Gladyshev VN. Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins. Bmc Biochemistry. 13: 21. PMID 23088625 DOI: 10.1186/1471-2091-13-21  1
2012 Gerashchenko MV, Lobanov AV, Gladyshev VN. Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 109: 17394-9. PMID 23045643 DOI: 10.1073/pnas.1120799109  1
2012 Gladyshev VN. On the cause of aging and control of lifespan: heterogeneity leads to inevitable damage accumulation, causing aging; control of damage composition and rate of accumulation define lifespan. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 34: 925-9. PMID 22915358 DOI: 10.1002/bies.201200092  1
2012 Carlson BA, Yoo MH, Tobe R, Mueller C, Naranjo-Suarez S, Hoffmann VJ, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis. Carcinogenesis. 33: 1806-13. PMID 22791808 DOI: 10.1093/carcin/bgs230  1
2012 Vinogradov DV, Tsoĭ OV, Zaika AV, Lobanov AV, Turanov AA, Gladyshev VN, Gel'fand MS. [Draft macronuclear genome of a ciliate Euplotes crassus]. Molekuliarnaia Biologiia. 46: 361-6. PMID 22670532  1
2012 Tarrago L, Kaya A, Weerapana E, Marino SM, Gladyshev VN. Methionine sulfoxide reductases preferentially reduce unfolded oxidized proteins and protect cells from oxidative protein unfolding. The Journal of Biological Chemistry. 287: 24448-59. PMID 22628550 DOI: 10.1074/jbc.M112.374520  1
2012 Tobe R, Yoo MH, Fradejas N, Carlson BA, Calvo S, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism. The Biochemical Journal. 445: 423-30. PMID 22594686 DOI: 10.1042/BJ20120618  1
2012 Ross F, Hernández P, Porcal W, López GV, Cerecetto H, González M, Basika T, Carmona C, Fló M, Maggioli G, Bonilla M, Gladyshev VN, Boiani M, Salinas G. Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites. Plos One. 7: e35033. PMID 22536349 DOI: 10.1371/journal.pone.0035033  0.36
2012 Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN. Composition and evolution of the vertebrate and mammalian selenoproteomes. Plos One. 7: e33066. PMID 22479358 DOI: 10.1371/journal.pone.0033066  1
2012 Kasaikina MV, Hatfield DL, Gladyshev VN. Understanding selenoprotein function and regulation through the use of rodent models. Biochimica Et Biophysica Acta. 1823: 1633-42. PMID 22440326 DOI: 10.1016/j.bbamcr.2012.02.018  1
2012 Naranjo-Suarez S, Carlson BA, Tsuji PA, Yoo MH, Gladyshev VN, Hatfield DL. HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia. Plos One. 7: e30470. PMID 22348009 DOI: 10.1371/journal.pone.0030470  1
2012 Marino SM, Gladyshev VN. Analysis and functional prediction of reactive cysteine residues. The Journal of Biological Chemistry. 287: 4419-25. PMID 22157013 DOI: 10.1074/jbc.R111.275578  1
2012 Fomenko DE, Gladyshev VN. Comparative genomics of thiol oxidoreductases reveals widespread and essential functions of thiol-based redox control of cellular processes. Antioxidants & Redox Signaling. 16: 193-201. PMID 21902454 DOI: 10.1089/ars.2011.3980  1
2012 Shumilina E, Soldà A, Gerashchenko M, Gladyshev VN, Dikiy A. ¹H, ¹³C, and ¹⁵N NMR resonance assignments of reduced full length and shortened forms of the Grx domain of Mus musculus TGR. Biomolecular Nmr Assignments. 6: 103-7. PMID 21901408 DOI: 10.1007/s12104-011-9335-0  1
2012 Malinouski M, Kehr S, Finney L, Vogt S, Carlson BA, Seravalli J, Jin R, Handy DE, Park TJ, Loscalzo J, Hatfield DL, Gladyshev VN. High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3. Antioxidants & Redox Signaling. 16: 185-92. PMID 21854231 DOI: 10.1089/ars.2011.3997  1
2012 Turanov AA, Malinouski M, Gladyshev VN. Selenium and male reproduction Selenium: Its Molecular Biology and Role in Human Health. 2147483647: 409-417. DOI: 10.1007/978-1-4614-1025-6_32  1
2012 Marino SM, Gladyshev VN, Dikiy A. Structural characterization of mammalian selenoproteins Selenium: Its Molecular Biology and Role in Human Health. 2147483647: 125-136. DOI: 10.1007/978-1-4614-1025-6_10  1
2011 Zhang Y, Rump S, Gladyshev VN. Comparative Genomics and Evolution of Molybdenum Utilization. Coordination Chemistry Reviews. 255: 1206-1217. PMID 22451726 DOI: 10.1016/j.ccr.2011.02.016  1
2011 Turanov AA, Xu XM, Carlson BA, Yoo MH, Gladyshev VN, Hatfield DL. Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis. Advances in Nutrition (Bethesda, Md.). 2: 122-8. PMID 22332041 DOI: 10.3945/an.110.000265  1
2011 Gladyshev VN, Zhang G, Wang J. The naked mole rat genome: understanding aging through genome analysis. Aging. 3: 1124. PMID 22199030  1
2011 Uluisik I, Kaya A, Fomenko DE, Karakaya HC, Carlson BA, Gladyshev VN, Koc A. Boron stress activates the general amino acid control mechanism and inhibits protein synthesis. Plos One. 6: e27772. PMID 22114689 DOI: 10.1371/journal.pone.0027772  1
2011 Shchedrina VA, Everley RA, Zhang Y, Gygi SP, Hatfield DL, Gladyshev VN. Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis. The Journal of Biological Chemistry. 286: 42937-48. PMID 22016385 DOI: 10.1074/jbc.M111.310920  1
2011 Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA, Yang P, Yim SH, Zhao X, Kasaikina MV, Stoletzki N, Peng C, ... ... Gladyshev VN, et al. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature. 479: 223-7. PMID 21993625 DOI: 10.1038/nature10533  1
2011 Aachmann FL, Kwak GH, Del Conte R, Kim HY, Gladyshev VN, Dikiy A. Structural and biochemical analysis of mammalian methionine sulfoxide reductase B2. Proteins. 79: 3123-31. PMID 21989933 DOI: 10.1002/prot.23141  1
2011 Carlson BA, Yoo MH, Conrad M, Gladyshev VN, Hatfield DL, Park JM. Protein kinase-regulated expression and immune function of thioredoxin reductase 1 in mouse macrophages. Molecular Immunology. 49: 311-6. PMID 21943784 DOI: 10.1016/j.molimm.2011.09.001  1
2011 Yim SH, Kim YJ, Oh SY, Fujii J, Zhang Y, Gladyshev VN, Rhee SG. Identification and characterization of alternatively transcribed form of peroxiredoxin IV gene that is specifically expressed in spermatids of postpubertal mouse testis. The Journal of Biological Chemistry. 286: 39002-12. PMID 21835919 DOI: 10.1074/jbc.M111.257220  1
2011 Lee BC, Fomenko DE, Gladyshev VN. Selective reduction of methylsulfinyl-containing compounds by mammalian MsrA suggests a strategy for improved drug efficacy. Acs Chemical Biology. 6: 1029-35. PMID 21823615 DOI: 10.1021/cb2001395  1
2011 Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, ... ... Gladyshev VN, et al. Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice. The Journal of Biological Chemistry. 286: 33203-12. PMID 21768092 DOI: 10.1074/jbc.M111.259218  1
2011 Kim JY, Carlson BA, Xu XM, Zeng Y, Chen S, Gladyshev VN, Lee BJ, Hatfield DL. Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA. Biochemical and Biophysical Research Communications. 409: 814-9. PMID 21624347 DOI: 10.1016/j.bbrc.2011.05.096  1
2011 Shchedrina VA, Kabil H, Vorbruggen G, Lee BC, Turanov AA, Hirosawa-Takamori M, Kim HY, Harshman LG, Hatfield DL, Gladyshev VN. Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of selenoproteins in stress resistance. The Journal of Biological Chemistry. 286: 29449-61. PMID 21622567 DOI: 10.1074/jbc.M111.257600  1
2011 Zhang Y, Gladyshev VN. Comparative genomics of trace element dependence in biology. The Journal of Biological Chemistry. 286: 23623-9. PMID 21566146 DOI: 10.1074/jbc.R110.172833  1
2011 Kasaikina MV, Kravtsova MA, Lee BC, Seravalli J, Peterson DA, Walter J, Legge R, Benson AK, Hatfield DL, Gladyshev VN. Dietary selenium affects host selenoproteome expression by influencing the gut microbiota. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2492-9. PMID 21493887 DOI: 10.1096/fj.11-181990  1
2011 Wu C, Parrott AM, Fu C, Liu T, Marino SM, Gladyshev VN, Jain MR, Baykal AT, Li Q, Oka S, Sadoshima J, Beuve A, Simmons WJ, Li H. Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies. Antioxidants & Redox Signaling. 15: 2565-604. PMID 21453190 DOI: 10.1089/ars.2010.3831  1
2011 Lee BC, Lobanov AV, Marino SM, Kaya A, Seravalli J, Hatfield DL, Gladyshev VN. A 4-selenocysteine, 2-selenocysteine insertion sequence (SECIS) element methionine sulfoxide reductase from Metridium senile reveals a non-catalytic function of selenocysteines. The Journal of Biological Chemistry. 286: 18747-55. PMID 21393246 DOI: 10.1074/jbc.M111.229807  1
2011 Kasaikina MV, Lobanov AV, Malinouski MY, Lee BC, Seravalli J, Fomenko DE, Turanov AA, Finney L, Vogt S, Park TJ, Miller RA, Hatfield DL, Gladyshev VN. Reduced utilization of selenium by naked mole rats due to a specific defect in GPx1 expression. The Journal of Biological Chemistry. 286: 17005-14. PMID 21372135 DOI: 10.1074/jbc.M110.216267  1
2011 Gobler CJ, Berry DL, Dyhrman ST, Wilhelm SW, Salamov A, Lobanov AV, Zhang Y, Collier JL, Wurch LL, Kustka AB, Dill BD, Shah M, VerBerkmoes NC, Kuo A, Terry A, ... ... Gladyshev VN, et al. Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics. Proceedings of the National Academy of Sciences of the United States of America. 108: 4352-7. PMID 21368207 DOI: 10.1073/pnas.1016106108  1
2011 Malinouski M, Zhou Y, Belousov VV, Hatfield DL, Gladyshev VN. Hydrogen peroxide probes directed to different cellular compartments. Plos One. 6: e14564. PMID 21283738 DOI: 10.1371/journal.pone.0014564  1
2011 Fomenko DE, Koc A, Agisheva N, Jacobsen M, Kaya A, Malinouski M, Rutherford JC, Siu KL, Jin DY, Winge DR, Gladyshev VN. Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide. Proceedings of the National Academy of Sciences of the United States of America. 108: 2729-34. PMID 21282621 DOI: 10.1073/pnas.1010721108  1
2011 Marino SM, Gladyshev VN. Proteomics: mapping reactive cysteines. Nature Chemical Biology. 7: 72-3. PMID 21245858 DOI: 10.1038/nchembio.513  1
2011 Suzuki Y, St Onge RP, Mani R, King OD, Heilbut A, Labunskyy VM, Chen W, Pham L, Zhang LV, Tong AH, Nislow C, Giaever G, Gladyshev VN, Vidal M, Schow P, et al. Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection. Nature Methods. 8: 159-64. PMID 21217751 DOI: 10.1038/nmeth.1550  1
2011 Kim MJ, Lee BC, Jeong J, Lee KJ, Hwang KY, Gladyshev VN, Kim HY. Tandem use of selenocysteine: adaptation of a selenoprotein glutaredoxin for reduction of selenoprotein methionine sulfoxide reductase. Molecular Microbiology. 79: 1194-203. PMID 21210868 DOI: 10.1111/j.1365-2958.2010.07500.x  1
2011 Labunskyy VM, Lee BC, Handy DE, Loscalzo J, Hatfield DL, Gladyshev VN. Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice. Antioxidants & Redox Signaling. 14: 2327-36. PMID 21194350 DOI: 10.1089/ars.2010.3526  1
2011 Ahmed ZM, Yousaf R, Lee BC, Khan SN, Lee S, Lee K, Husnain T, Rehman AU, Bonneux S, Ansar M, Ahmad W, Leal SM, Gladyshev VN, Belyantseva IA, Van Camp G, et al. Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74. American Journal of Human Genetics. 88: 19-29. PMID 21185009 DOI: 10.1016/j.ajhg.2010.11.010  1
2011 Lee BC, Gladyshev VN. The biological significance of methionine sulfoxide stereochemistry. Free Radical Biology & Medicine. 50: 221-7. PMID 21075204 DOI: 10.1016/j.freeradbiomed.2010.11.008  1
2011 Bonilla M, Denicola A, Marino SM, Gladyshev VN, Salinas G. Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation. The Journal of Biological Chemistry. 286: 4959-67. PMID 21051543 DOI: 10.1074/jbc.M110.170761  1
2011 Marino SM, Gladyshev VN. Redox biology: computational approaches to the investigation of functional cysteine residues. Antioxidants & Redox Signaling. 15: 135-46. PMID 20812876 DOI: 10.1089/ars.2010.3561  1
2011 Goponenko AV, Boyle BJ, Jahan KI, Gerashchenko MV, Fomenko DE, Gladyshev VN, Dzenis YA. Use of environmental scanning electron microscopy for in situ observation of interaction of cells with micro- and nanoprobes Micro and Nano Letters. 6: 603-608. DOI: 10.1049/mnl.2011.0166  1
2011 Hatfield DL, Berry MJ, Gladyshev VN. Preface Selenium: Its Molecular Biology and Role in Human Health. xi-xii. DOI: 10.1007/978-1-4614-1025-6  1
2010 Xu XM, Turanov AA, Carlson BA, Yoo MH, Everley RA, Nandakumar R, Sorokina I, Gygi SP, Gladyshev VN, Hatfield DL. Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery. Proceedings of the National Academy of Sciences of the United States of America. 107: 21430-4. PMID 21115847 DOI: 10.1073/pnas.1009947107  1
2010 Marino SM, Gladyshev VN. Cysteine function governs its conservation and degeneration and restricts its utilization on protein surfaces. Journal of Molecular Biology. 404: 902-16. PMID 20950627 DOI: 10.1016/j.jmb.2010.09.027  1
2010 Hacioglu E, Esmer I, Fomenko DE, Gladyshev VN, Koc A. The roles of thiol oxidoreductases in yeast replicative aging. Mechanisms of Ageing and Development. 131: 692-9. PMID 20934449 DOI: 10.1016/j.mad.2010.09.006  1
2010 Sengupta A, Lichti UF, Carlson BA, Ryscavage AO, Gladyshev VN, Yuspa SH, Hatfield DL. Selenoproteins are essential for proper keratinocyte function and skin development. Plos One. 5: e12249. PMID 20805887 DOI: 10.1371/journal.pone.0012249  1
2010 Kaya A, Koc A, Lee BC, Fomenko DE, Rederstorff M, Krol A, Lescure A, Gladyshev VN. Compartmentalization and regulation of mitochondrial function by methionine sulfoxide reductases in yeast. Biochemistry. 49: 8618-25. PMID 20799725 DOI: 10.1021/bi100908v  1
2010 Marino SM, Li Y, Fomenko DE, Agisheva N, Cerny RL, Gladyshev VN. Characterization of surface-exposed reactive cysteine residues in Saccharomyces cerevisiae. Biochemistry. 49: 7709-21. PMID 20698499 DOI: 10.1021/bi100677a  1
2010 Liang X, Fomenko DE, Hua D, Kaya A, Gladyshev VN. Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing. Plos One. 5: e11497. PMID 20634897 DOI: 10.1371/journal.pone.0011497  1
2010 Yoo MH, Carlson BA, Tsuji P, Irons R, Gladyshev VN, Hatfield DL. Alteration of thioredoxin reductase 1 levels in elucidating cancer etiology. Methods in Enzymology. 474: 255-75. PMID 20609915 DOI: 10.1016/S0076-6879(10)74015-5  1
2010 Turanov AA, Hatfield DL, Gladyshev VN. Characterization of protein targets of mammalian thioredoxin reductases. Methods in Enzymology. 474: 245-54. PMID 20609914 DOI: 10.1016/S0076-6879(10)74014-3  1
2010 Aachmann FL, Sal LS, Kim HY, Marino SM, Gladyshev VN, Dikiy A. Insights into function, catalytic mechanism, and fold evolution of selenoprotein methionine sulfoxide reductase B1 through structural analysis. The Journal of Biological Chemistry. 285: 33315-23. PMID 20605785 DOI: 10.1074/jbc.M110.132308  1
2010 Carlson BA, Yoo MH, Shrimali RK, Irons R, Gladyshev VN, Hatfield DL, Park JM. Role of selenium-containing proteins in T-cell and macrophage function. The Proceedings of the Nutrition Society. 69: 300-10. PMID 20576203 DOI: 10.1017/S002966511000176X  1
2010 Turanov AA, Kehr S, Marino SM, Yoo MH, Carlson BA, Hatfield DL, Gladyshev VN. Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets. The Biochemical Journal. 430: 285-93. PMID 20536427 DOI: 10.1042/BJ20091378  1
2010 Lobanov AV, Turanov AA, Hatfield DL, Gladyshev VN. Dual functions of codons in the genetic code. Critical Reviews in Biochemistry and Molecular Biology. 45: 257-65. PMID 20446809 DOI: 10.3109/10409231003786094  1
2010 Irons R, Tsuji PA, Carlson BA, Ouyang P, Yoo MH, Xu XM, Hatfield DL, Gladyshev VN, Davis CD. Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 630-9. PMID 20388823 DOI: 10.1158/1940-6207.CAPR-10-0003  1
2010 Otero L, Bonilla M, Protasio AV, Fernández C, Gladyshev VN, Salinas G. Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths. Bmc Genomics. 11: 237. PMID 20385027 DOI: 10.1186/1471-2164-11-237  1
2010 Zhang Y, Gladyshev VN. dbTEU: a protein database of trace element utilization. Bioinformatics (Oxford, England). 26: 700-2. PMID 20053843 DOI: 10.1093/bioinformatics/btp705  1
2010 Gerashchenko MV, Su D, Gladyshev VN. CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes. The Journal of Biological Chemistry. 285: 4595-602. PMID 20018845 DOI: 10.1074/jbc.M109.070532  1
2010 Zhang Y, Gladyshev VN. General trends in trace element utilization revealed by comparative genomic analyses of Co, Cu, Mo, Ni, and Se. The Journal of Biological Chemistry. 285: 3393-405. PMID 19887375 DOI: 10.1074/jbc.M109.071746  1
2010 Marino SM, Gladyshev VN. Structural analysis of cysteine S-nitrosylation: a modified acid-based motif and the emerging role of trans-nitrosylation. Journal of Molecular Biology. 395: 844-59. PMID 19854201 DOI: 10.1016/j.jmb.2009.10.042  1
2010 Bekaert M, Firth AE, Zhang Y, Gladyshev VN, Atkins JF, Baranov PV. Recode-2: new design, new search tools, and many more genes. Nucleic Acids Research. 38: D69-74. PMID 19783826 DOI: 10.1093/nar/gkp788  1
2010 Yoo MH, Gu X, Xu XM, Kim JY, Carlson BA, Patterson AD, Cai H, Gladyshev VN, Hatfield DL. Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease. Antioxidants & Redox Signaling. 12: 819-27. PMID 19769463 DOI: 10.1089/ars.2009.2891  1
2010 Novoselov SV, Kim HY, Hua D, Lee BC, Astle CM, Harrison DE, Friguet B, Moustafa ME, Carlson BA, Hatfield DL, Gladyshev VN. Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice. Antioxidants & Redox Signaling. 12: 829-38. PMID 19769460 DOI: 10.1089/ars.2009.2895  1
2010 Shchedrina VA, Zhang Y, Labunskyy VM, Hatfield DL, Gladyshev VN. Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins. Antioxidants & Redox Signaling. 12: 839-49. PMID 19747065 DOI: 10.1089/ars.2009.2865  1
2009 Sengupta A, Carlson BA, Labunskyy VM, Gladyshev VN, Hatfield DL. Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 953-61. PMID 19935881 DOI: 10.1139/o09-064  1
2009 Carlson BA, Yoo MH, Sano Y, Sengupta A, Kim JY, Irons R, Gladyshev VN, Hatfield DL, Park JM. Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression. Bmc Immunology. 10: 57. PMID 19863805 DOI: 10.1186/1471-2172-10-57  1
2009 Jin BY, Sartoretto JL, Gladyshev VN, Michel T. Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 17343-8. PMID 19805165 DOI: 10.1073/pnas.0907409106  1
2009 Carlson BA, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL. Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development. Molecules (Basel, Switzerland). 14: 3509-27. PMID 19783940 DOI: 10.3390/molecules14093509  1
2009 Xu XM, Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL. Simultaneous knockdown of the expression of two genes using multiple shRNAs and subsequent knock-in of their expression. Nature Protocols. 4: 1338-48. PMID 19713955 DOI: 10.1038/nprot.2009.145  1
2009 Labunskyy VM, Yoo MH, Hatfield DL, Gladyshev VN. Sep15, a thioredoxin-like selenoprotein, is involved in the unfolded protein response and differentially regulated by adaptive and acute ER stresses. Biochemistry. 48: 8458-65. PMID 19650649 DOI: 10.1021/bi900717p  1
2009 Lobanov AV, Hatfield DL, Gladyshev VN. Eukaryotic selenoproteins and selenoproteomes. Biochimica Et Biophysica Acta. 1790: 1424-8. PMID 19477234 DOI: 10.1016/j.bbagen.2009.05.014  1
2009 Zhang Y, Gladyshev VN. Comparative genomics of trace elements: emerging dynamic view of trace element utilization and function. Chemical Reviews. 109: 4828-61. PMID 19459624 DOI: 10.1021/cr800557s  1
2009 Marino SM, Gladyshev VN. A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues. Plos Computational Biology. 5: e1000383. PMID 19424433 DOI: 10.1371/journal.pcbi.1000383  1
2009 Kaya A, Karakaya HC, Fomenko DE, Gladyshev VN, Koc A. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Molecular and Cellular Biology. 29: 3665-74. PMID 19414602 DOI: 10.1128/MCB.01646-08  1
2009 Shchedrina VA, Vorbrüggen G, Lee BC, Kim HY, Kabil H, Harshman LG, Gladyshev VN. Overexpression of methionine-R-sulfoxide reductases has no influence on fruit fly aging. Mechanisms of Ageing and Development. 130: 429-43. PMID 19409408 DOI: 10.1016/j.mad.2009.04.003  1
2009 Lee BC, Dikiy A, Kim HY, Gladyshev VN. Functions and evolution of selenoprotein methionine sulfoxide reductases. Biochimica Et Biophysica Acta. 1790: 1471-7. PMID 19406207 DOI: 10.1016/j.bbagen.2009.04.014  1
2009 Kehr S, Malinouski M, Finney L, Vogt S, Labunskyy VM, Kasaikina MV, Carlson BA, Zhou Y, Hatfield DL, Gladyshev VN. X-ray fluorescence microscopy reveals the role of selenium in spermatogenesis. Journal of Molecular Biology. 389: 808-18. PMID 19379757 DOI: 10.1016/j.jmb.2009.04.024  1
2009 Hatfield DL, Gladyshev VN. The Outcome of Selenium and Vitamin E Cancer Prevention Trial (SELECT) reveals the need for better understanding of selenium biology. Molecular Interventions. 9: 18-21. PMID 19299660 DOI: 10.1124/mi.9.1.6  1
2009 Hatfield DL, Yoo MH, Carlson BA, Gladyshev VN. Selenoproteins that function in cancer prevention and promotion. Biochimica Et Biophysica Acta. 1790: 1541-5. PMID 19272412 DOI: 10.1016/j.bbagen.2009.03.001  1
2009 Zhang Y, Rodionov DA, Gelfand MS, Gladyshev VN. Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization. Bmc Genomics. 10: 78. PMID 19208259 DOI: 10.1186/1471-2164-10-78  1
2009 Turanov AA, Lobanov AV, Fomenko DE, Morrison HG, Sogin ML, Klobutcher LA, Hatfield DL, Gladyshev VN. Genetic code supports targeted insertion of two amino acids by one codon. Science (New York, N.Y.). 323: 259-61. PMID 19131629 DOI: 10.1126/science.1164748  1
2009 Le DT, Lee BC, Marino SM, Zhang Y, Fomenko DE, Kaya A, Hacioglu E, Kwak GH, Koc A, Kim HY, Gladyshev VN. Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 4354-64. PMID 19049972 DOI: 10.1074/jbc.M805891200  1
2009 Fomenko DE, Novoselov SV, Natarajan SK, Lee BC, Koc A, Carlson BA, Lee TH, Kim HY, Hatfield DL, Gladyshev VN. MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form. The Journal of Biological Chemistry. 284: 5986-93. PMID 18990697 DOI: 10.1074/jbc.M805770200  1
2009 Carlson BA, Schweizer U, Perella C, Shrimali RK, Feigenbaum L, Shen L, Speransky S, Floss T, Jeong SJ, Watts J, Hoffmann V, Combs GF, Gladyshev VN, Hatfield DL. The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice. The Biochemical Journal. 418: 61-71. PMID 18973473 DOI: 10.1042/BJ20081304  1
2009 Hirosawa-Takamori M, Ossipov D, Novoselov SV, Turanov AA, Zhang Y, Gladyshev VN, Krol A, Vorbrüggen G, Jäckle H. A novel stem loop control element-dependent UGA read-through system without translational selenocysteine incorporation in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 107-13. PMID 18772345 DOI: 10.1096/fj.08-116640  1
2009 Kim HY, Zhang Y, Lee BC, Kim JR, Gladyshev VN. The selenoproteome of Clostridium sp. OhILAs: characterization of anaerobic bacterial selenoprotein methionine sulfoxide reductase A. Proteins. 74: 1008-17. PMID 18767149 DOI: 10.1002/prot.22212  1
2009 Jin BY, Sartoretto JL, Gladyshev VN, Michel T. Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 41, (17343-17348) 10.1073/pnas.0907409106) Proceedings of the National Academy of Sciences of the United States of America. 106: 18426. DOI: 10.1073/pnas.0911347106  1
2008 Breivik AS, Aachmann FL, Sal LS, Kim HY, Del Conte R, del Conte R, Gladyshev VN, Dikiy A. 1H, 15N and 13C NMR assignments of mouse methionine sulfoxide reductase B2. Biomolecular Nmr Assignments. 2: 199-201. PMID 19636904 DOI: 10.1007/s12104-008-9120-x  1
2008 Papp LV, Wang J, Kennedy D, Boucher D, Zhang Y, Gladyshev VN, Singh RN, Khanna KK. Functional characterization of alternatively spliced human SECISBP2 transcript variants. Nucleic Acids Research. 36: 7192-206. PMID 19004874 DOI: 10.1093/nar/gkn829  0.76
2008 Lee BC, Le DT, Gladyshev VN. Mammals reduce methionine-S-sulfoxide with MsrA and are unable to reduce methionine-R-sulfoxide, and this function can be restored with a yeast reductase. The Journal of Biological Chemistry. 283: 28361-9. PMID 18697736 DOI: 10.1074/jbc.M805059200  1
2008 Fomenko DE, Marino SM, Gladyshev VN. Functional diversity of cysteine residues in proteins and unique features of catalytic redox-active cysteines in thiol oxidoreductases. Molecules and Cells. 26: 228-35. PMID 18648218  1
2008 Zhang Y, Gladyshev VN. Trends in selenium utilization in marine microbial world revealed through the analysis of the global ocean sampling (GOS) project. Plos Genetics. 4: e1000095. PMID 18551170 DOI: 10.1371/journal.pgen.1000095  1
2008 Zhang Y, Turanov AA, Hatfield DL, Gladyshev VN. In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait. Bmc Genomics. 9: 251. PMID 18510720 DOI: 10.1186/1471-2164-9-251  1
2008 Le DT, Liang X, Fomenko DE, Raza AS, Chong CK, Carlson BA, Hatfield DL, Gladyshev VN. Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms. Biochemistry. 47: 6685-94. PMID 18505275 DOI: 10.1021/bi800422s  1
2008 Shrimali RK, Irons RD, Carlson BA, Sano Y, Gladyshev VN, Park JM, Hatfield DL. Selenoproteins mediate T cell immunity through an antioxidant mechanism. The Journal of Biological Chemistry. 283: 20181-5. PMID 18487203 DOI: 10.1074/jbc.M802559200  1
2008 Zhang Y, Gladyshev VN. Molybdoproteomes and evolution of molybdenum utilization. Journal of Molecular Biology. 379: 881-99. PMID 18485362 DOI: 10.1016/j.jmb.2008.03.051  1
2008 Bonilla M, Denicola A, Novoselov SV, Turanov AA, Protasio A, Izmendi D, Gladyshev VN, Salinas G. Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione. The Journal of Biological Chemistry. 283: 17898-907. PMID 18408002 DOI: 10.1074/jbc.M710609200  1
2008 Lobanov AV, Hatfield DL, Gladyshev VN. Reduced reliance on the trace element selenium during evolution of mammals Genome Biology. 9. PMID 18377657 DOI: 10.1186/gb-2008-9-3-r62  1
2008 Sengupta A, Carlson BA, Weaver JA, Novoselov SV, Fomenko DE, Gladyshev VN, Hatfield DL. A functional link between housekeeping selenoproteins and phase II enzymes. The Biochemical Journal. 413: 151-61. PMID 18373496 DOI: 10.1042/BJ20080277  1
2008 Castellano S, Gladyshev VN, Guigó R, Berry MJ. SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements. Nucleic Acids Research. 36: D332-8. PMID 18174224 DOI: 10.1093/nar/gkm731  1
2008 Ridge PG, Zhang Y, Gladyshev VN. Comparative genomic analyses of copper transporters and cuproproteomes reveal evolutionary dynamics of copper utilization and its link to oxygen. Plos One. 3: e1378. PMID 18167539 DOI: 10.1371/journal.pone.0001378  1
2008 Lobanov AV, Hatfield DL, Gladyshev VN. Selenoproteinless animals: Selenophosphate synthetase SPS1 functions in a pathway unrelated to selenocysteine biosynthesis Protein Science. 17: 176-182. PMID 18156471 DOI: 10.1110/ps.073261508  1
2008 Ganichkin OM, Xu XM, Carlson BA, Mix H, Hatfield DL, Gladyshev VN, Wahl MC. Structure and catalytic mechanism of eukaryotic selenocysteine synthase. The Journal of Biological Chemistry. 283: 5849-65. PMID 18093968 DOI: 10.1074/jbc.M709342200  1
2008 Sengupta A, Carlson BA, Hoffmann VJ, Gladyshev VN, Hatfield DL. Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolism. Biochemical and Biophysical Research Communications. 365: 446-52. PMID 17996733 DOI: 10.1016/j.bbrc.2007.10.189  1
2007 Sal LS, Aachmann FL, Kim HY, Gladyshev VN, Dikiy A. NMR assignments of 1H, 13C and 15N spectra of methionine sulfoxide reductase B1 from Mus musculus. Biomolecular Nmr Assignments. 1: 131-3. PMID 19636847 DOI: 10.1007/s12104-007-9039-7  1
2007 Yoo MH, Xu XM, Carlson BA, Patterson AD, Gladyshev VN, Hatfield DL. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. Plos One. 2: e1112. PMID 17971875 DOI: 10.1371/journal.pone.0001112  1
2007 Aachmann FL, Fomenko DE, Soragni A, Gladyshev VN, Dikiy A. Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins. The Journal of Biological Chemistry. 282: 37036-44. PMID 17928294 DOI: 10.1074/jbc.M705410200  1
2007 Kim HY, Gladyshev VN. Methionine sulfoxide reductases: Selenoprotein forms and roles in antioxidant protein repair in mammals Biochemical Journal. 407: 321-329. PMID 17922679 DOI: 10.1042/BJ20070929  1
2007 Xu XM, Carlson BA, Zhang Y, Mix H, Kryukov GV, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL. New developments in selenium biochemistry: selenocysteine biosynthesis in eukaryotes and archaea. Biological Trace Element Research. 119: 234-41. PMID 17916946 DOI: 10.1007/s12011-007-8003-9  1
2007 Shchedrina VA, Novoselov SV, Malinouski MY, Gladyshev VN. Identification and characterization of a selenoprotein family containing a diselenide bond in a redox motif. Proceedings of the National Academy of Sciences of the United States of America. 104: 13919-24. PMID 17715293 DOI: 10.1073/pnas.0703448104  1
2007 Zhang Y, Gladyshev VN. High content of proteins containing 21st and 22nd amino acids, selenocysteine and pyrrolysine, in a symbiotic deltaproteobacterium of gutless worm Olavius algarvensis Nucleic Acids Research. 35: 4952-4963. PMID 17626042 DOI: 10.1093/nar/gkm514  1
2007 Su D, Berndt C, Fomenko DE, Holmgren A, Gladyshev VN. A conserved cis-proline precludes metal binding by the active site thiolates in members of the thioredoxin family of proteins. Biochemistry. 46: 6903-10. PMID 17503777 DOI: 10.1021/bi700152b  1
2007 Novoselov SV, Lobanov AV, Hua D, Kasaikina MV, Hatfield DL, Gladyshev VN. A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 7857-62. PMID 17470795 DOI: 10.1073/pnas.0610683104  1
2007 Yoo MH, Xu XM, Turanov AA, Carlson BA, Gladyshev VN, Hatfield DL. A new strategy for assessing selenoprotein function: siRNA knockdown/knock-in targeting the 3'-UTR. Rna (New York, N.Y.). 13: 921-9. PMID 17468436 DOI: 10.1261/rna.533007  1
2007 Koc A, Gladyshev VN. Methionine sulfoxide reduction and the aging process. Annals of the New York Academy of Sciences. 1100: 383-6. PMID 17460202 DOI: 10.1196/annals.1395.042  1
2007 Labunskyy VM, Hatfield DL, Gladyshev VN. The Sep15 protein family: roles in disulfide bond formation and quality control in the endoplasmic reticulum. Iubmb Life. 59: 1-5. PMID 17365173 DOI: 10.1080/15216540601126694  1
2007 Xu XM, Carlson BA, Irons R, Mix H, Zhong N, Gladyshev VN, Hatfield DL. Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis. The Biochemical Journal. 404: 115-20. PMID 17346238 DOI: 10.1042/BJ20070165  1
2007 Novoselov SV, Kryukov GV, Xu XM, Carlson BA, Hatfield DL, Gladyshev VN. Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern. The Journal of Biological Chemistry. 282: 11960-8. PMID 17337453 DOI: 10.1074/jbc.M701605200  1
2007 Fomenko DE, Xing W, Adair BM, Thomas DJ, Gladyshev VN. High-throughput identification of catalytic redox-active cysteine residues. Science (New York, N.Y.). 315: 387-9. PMID 17234949 DOI: 10.1126/science.1133114  1
2007 Mix H, Lobanov AV, Gladyshev VN. SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes Nucleic Acids Research. 35: 414-423. PMID 17169995 DOI: 10.1093/nar/gkl1060  1
2006 Kim HY, Fomenko DE, Yoon YE, Gladyshev VN. Catalytic advantages provided by selenocysteine in methionine-S-sulfoxide reductases. Biochemistry. 45: 13697-704. PMID 17105189 DOI: 10.1021/bi0611614  1
2006 Fernando MR, Lechner JM, Löfgren S, Gladyshev VN, Lou MF. Mitochondrial thioltransferase (glutaredoxin 2) has GSH-dependent and thioredoxin reductase-dependent peroxidase activities in vitro and in lens epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2645-7. PMID 17065220 DOI: 10.1096/fj.06-5919fje  1
2006 Zhang Y, Romero H, Salinas G, Gladyshev VN. Dynamic evolution of selenocysteine utilization in bacteria: A balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues Genome Biology. 7. PMID 17054778 DOI: 10.1186/gb-2006-7-10-r94  1
2006 Lobanov AV, Gromer S, Salinas G, Gladyshev VN. Selenium metabolism in Trypanosoma: Characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein Nucleic Acids Research. 34: 4012-4024. PMID 16914442 DOI: 10.1093/nar/gkl541  1
2006 Hatfield DL, Carlson BA, Xu XM, Mix H, Gladyshev VN. Selenocysteine incorporation machinery and the role of selenoproteins in development and health. Progress in Nucleic Acid Research and Molecular Biology. 81: 97-142. PMID 16891170 DOI: 10.1016/S0079-6603(06)81003-2  1
2006 Turanov AA, Su D, Gladyshev VN. Characterization of alternative cytosolic forms and cellular targets of mouse mitochondrial thioredoxin reductase. The Journal of Biological Chemistry. 281: 22953-63. PMID 16774913 DOI: 10.1074/jbc.M604326200  1
2006 Lobanov AV, Kryukov GV, Hatfield DL, Gladyshev VN. Is there a twenty third amino acid in the genetic code? Trends in Genetics : Tig. 22: 357-60. PMID 16713651 DOI: 10.1016/j.tig.2006.05.002  1
2006 Eckenroth B, Harris K, Turanov AA, Gladyshev VN, Raines RT, Hondal RJ. Semisynthesis and characterization of mammalian thioredoxin reductase. Biochemistry. 45: 5158-70. PMID 16618105 DOI: 10.1021/bi0517887  1
2006 Yoo MH, Xu XM, Carlson BA, Gladyshev VN, Hatfield DL. Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells. The Journal of Biological Chemistry. 281: 13005-8. PMID 16565519 DOI: 10.1074/jbc.C600012200  1
2006 Kim HY, Gladyshev VN. Alternative first exon splicing regulates subcellular distribution of methionine sulfoxide reductases Bmc Molecular Biology. 7. PMID 16542431 DOI: 10.1186/1471-2199-7-11  1
2006 Lobanov AV, Delgado C, Rahlfs S, Novoselov SV, Kryukov GV, Gromer S, Hatfield DL, Becker K, Gladyshev VN. The Plasmodium selenoproteome. Nucleic Acids Research. 34: 496-505. PMID 16428245 DOI: 10.1093/nar/gkj450  1
2006 Ferguson AD, Labunskyy VM, Fomenko DE, Araç D, Chelliah Y, Amezcua CA, Rizo J, Gladyshev VN, Deisenhofer J. NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family. The Journal of Biological Chemistry. 281: 3536-43. PMID 16319061 DOI: 10.1074/jbc.M511386200  1
2006 Novoselov SV, Hua D, Lobanov AV, Gladyshev VN. Identification and characterization of Fep15, a new selenocysteine- containing member of the Sep15 protein family Biochemical Journal. 394: 575-579. PMID 16236027 DOI: 10.1042/BJ20051569  1
2006 Gladyshev VN. Selenoproteins and selenoproteomes Selenium: Its Molecular Biology and Role in Human Health, Second Edition. 99-110. DOI: 10.1007/0-387-33827-6_9  1
2006 Salinas G, Romero H, Xu XM, Carlson BA, Hatfield DL, Gladyshev VN. Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization Selenium: Its Molecular Biology and Role in Human Health, Second Edition. 39-50. DOI: 10.1007/0-387-33827-6_4  1
2006 Salinas G, Lobanov AV, Gladyshev VN. Selenoproteins in parasites Selenium: Its Molecular Biology and Role in Human Health, Second Edition. 355-366. DOI: 10.1007/0-387-33827-6_31  1
2006 Labunskyy VM, Gladyshev VN, Hatfield DL. The 15-kDa selenoprotein (Sep15): Functional analysis and role in cancer Selenium: Its Molecular Biology and Role in Human Health, Second Edition. 141-148. DOI: 10.1007/0-387-33827-6_13  1
2006 Hatfield DL, Berry MJ, Gladyshev VN. Selenium: Its molecular biology and role in human health, second edition Selenium: Its Molecular Biology and Role in Human Health, Second Edition. 1-419. DOI: 10.1007/0-387-33827-6  1
2005 Kim HY, Gladyshev VN. Different catalytic mechanisms in mammalian selenocysteine- and cysteine-containing methionine-R-sulfoxide reductases Plos Biology. 3. PMID 16262444 DOI: 10.1371/journal.pbio.0030375  1
2005 Sun QA, Su D, Novoselov SV, Carlson BA, Hatfield DL, Gladyshev VN. Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase. Biochemistry. 44: 14528-37. PMID 16262253 DOI: 10.1021/bi051321w  1
2005 Biterova EI, Turanov AA, Gladyshev VN, Barycki JJ. Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 15018-23. PMID 16217027 DOI: 10.1073/pnas.0504218102  1
2005 Novoselov SV, Calvisi DF, Labunskyy VM, Factor VM, Carlson BA, Fomenko DE, Moustafa ME, Hatfield DL, Gladyshev VN. Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice. Oncogene. 24: 8003-11. PMID 16170372 DOI: 10.1038/sj.onc.1208940  1
2005 Labunskyy VM, Ferguson AD, Fomenko DE, Chelliah Y, Hatfield DL, Gladyshev VN. A novel cysteine-rich domain of Sep15 mediates the interaction with UDP-glucose:glycoprotein glucosyltransferase. The Journal of Biological Chemistry. 280: 37839-45. PMID 16129668 DOI: 10.1074/jbc.M508685200  1
2005 Romero H, Zhang Y, Gladyshev VN, Salinas G. Evolution of selenium utilization traits Genome Biology. 6. PMID 16086848  1
2005 Kim HY, Gladyshev VN. Role of structural and functional elements of mouse methionine-S-sulfoxide reductase in its subcellular distribution Biochemistry. 44: 8059-8067. PMID 15924425 DOI: 10.1021/bi0501131  1
2005 Su D, Novoselov SV, Sun QA, Moustafa ME, Zhou Y, Oko R, Hatfield DL, Gladyshev VN. Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation. The Journal of Biological Chemistry. 280: 26491-8. PMID 15901730 DOI: 10.1074/jbc.M503638200  0.96
2005 Su D, Li Y, Gladyshev VN. Selenocysteine insertion directed by the 3'-UTR SECIS element in Escherichia coli. Nucleic Acids Research. 33: 2486-92. PMID 15863725 DOI: 10.1093/nar/gki547  1
2005 Taskov K, Chapple C, Kryukov GV, Castellano S, Lobanov AV, Korotkov KV, Guigó R, Gladyshev VN. Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome? Nucleic Acids Research. 33: 2227-38. PMID 15843685 DOI: 10.1093/nar/gki507  1
2005 Zhang Y, Fomenko DE, Gladyshev VN. The microbial selenoproteome of the Sargasso Sea. Genome Biology. 6: R37. PMID 15833124 DOI: 10.1186/gb-2005-6-4-r37  1
2005 Zhang Y, Gladyshev VN. An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes Bioinformatics. 21: 2580-2589. PMID 15797911 DOI: 10.1093/bioinformatics/bti400  1
2005 Zhang Y, Baranov PV, Atkins JF, Gladyshev VN. Pyrrolysine and selenocysteine use dissimilar decoding strategies Journal of Biological Chemistry. 280: 20740-20751. PMID 15788401 DOI: 10.1074/jbc.M501458200  1
2005 Carlson BA, Xu XM, Gladyshev VN, Hatfield DL. Selective rescue of selenoprotein expression in mice lacking a highly specialized methyl group in selenocysteine tRNA. The Journal of Biological Chemistry. 280: 5542-8. PMID 15611090 DOI: 10.1074/jbc.M411725200  1
2004 Su D, Gladyshev VN. Alternative splicing involving the thioredoxin reductase module in mammals: a glutaredoxin-containing thioredoxin reductase 1. Biochemistry. 43: 12177-88. PMID 15379556 DOI: 10.1021/bi048478t  1
2004 Carlson BA, Xu XM, Kryukov GV, Rao M, Berry MJ, Gladyshev VN, Hatfield DL. Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase. Proceedings of the National Academy of Sciences of the United States of America. 101: 12848-53. PMID 15317934 DOI: 10.1073/pnas.0402636101  1
2004 Kim HY, Gladyshev VN. Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase Biochemical and Biophysical Research Communications. 320: 1277-1283. PMID 15249228 DOI: 10.1016/j.bbrc.2004.06.078  1
2004 Gladyshev VN, Kryukov GV, Fomenko DE, Hatfield DL. Identification of trace element-containing proteins in genomic databases. Annual Review of Nutrition. 24: 579-96. PMID 15189132 DOI: 10.1146/annurev.nutr.24.012003.132241  1
2004 Koc A, Gasch AP, Rutherford JC, Kim HY, Gladyshev VN. Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proceedings of the National Academy of Sciences of the United States of America. 101: 7999-8004. PMID 15141092 DOI: 10.1073/pnas.0307929101  1
2004 Kryukov GV, Gladyshev VN. The prokaryotic selenoproteome. Embo Reports. 5: 538-43. PMID 15105824 DOI: 10.1038/sj.embor.7400126  1
2004 Castellano S, Novoselov SV, Kryukov GV, Lescure A, Blanco E, Krol A, Gladyshev VN, Guigó R. Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution. Embo Reports. 5: 71-7. PMID 14710190 DOI: 10.1038/sj.embor.7400036  1
2004 Kim HY, Gladyshev VN. Methionine Sulfoxide Reduction in Mammals: Characterization of Methionine-R-Sulfoxide Reductases Molecular Biology of the Cell. 15: 1055-1064. PMID 14699060 DOI: 10.1091/mbc.E03-08-0629  1
2004 Carlson BA, Novoselov SV, Kumaraswamy E, Lee BJ, Anver MR, Gladyshev VN, Hatfield DL. Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function. The Journal of Biological Chemistry. 279: 8011-7. PMID 14660662 DOI: 10.1074/jbc.M310470200  1
2004 Wang C, Scott SD, Tao Q, Fomenko DE, Gladyshev VN. New techniques for generation and analysis of evolutionary trees Proceedings of the International Conference On Mathematics and Engineering Techniques in Medicine and Biological Sciences, Metmbs'04. 283-289.  1
2003 Fomenko DE, Gladyshev VN. Identity and functions of CxxC-derived motifs. Biochemistry. 42: 11214-25. PMID 14503871 DOI: 10.1021/bi034459s  1
2003 Fomenko DE, Gladyshev VN. Genomics perspective on disulfide bond formation. Antioxidants & Redox Signaling. 5: 397-402. PMID 13678527 DOI: 10.1089/152308603768295131  1
2003 Thisse C, Degrave A, Kryukov GV, Gladyshev VN, Obrecht-Pflumio S, Krol A, Thisse B, Lescure A. Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish. Gene Expression Patterns : Gep. 3: 525-32. PMID 12915322 DOI: 10.1016/S1567-133X(03)00054-1  1
2003 Rao M, Carlson BA, Novoselov SV, Weeks DP, Gladyshev VN, Hatfield DL. Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec. Rna (New York, N.Y.). 9: 923-30. PMID 12869703 DOI: 10.1261/rna.5510503  1
2003 Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigó R, Gladyshev VN. Characterization of mammalian selenoproteomes. Science (New York, N.Y.). 300: 1439-43. PMID 12775843 DOI: 10.1126/science.1083516  1
2003 Kumaraswamy E, Carlson BA, Morgan F, Miyoshi K, Robinson GW, Su D, Wang S, Southon E, Tessarollo L, Lee BJ, Gladyshev VN, Hennighausen L, Hatfield DL. Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Molecular and Cellular Biology. 23: 1477-88. PMID 12588969 DOI: 10.1128/MCB.23.5.1477-1488.2003  1
2003 Novoselov SV, Gladyshev VN. Non-animal origin of animal thioredoxin reductases: Implications for selenocysteine evolution and evolution of protein function through carboxy-terminal extensions Protein Science. 12: 372-378. PMID 12538901 DOI: 10.1110/ps.0226503  1
2002 Fomenko DE, Gladyshev VN. CxxS: fold-independent redox motif revealed by genome-wide searches for thiol/disulfide oxidoreductase function. Protein Science : a Publication of the Protein Society. 11: 2285-96. PMID 12237451 DOI: 10.1110/ps.0218302  1
2002 Kumar RA, Koc A, Cerny RL, Gladyshev VN. Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase. The Journal of Biological Chemistry. 277: 37527-35. PMID 12145281 DOI: 10.1074/jbc.M203496200  1
2002 Novoselov SV, Rao M, Onoshko NV, Zhi H, Kryukov GV, Xiang Y, Weeks DP, Hatfield DL, Gladyshev VN. Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii. The Embo Journal. 21: 3681-93. PMID 12110581 DOI: 10.1093/emboj/cdf372  1
2002 Hatfield DL, Gladyshev VN. How selenium has altered our understanding of the genetic code Molecular and Cellular Biology. 22: 3565-3576. PMID 11997494 DOI: 10.1128/MCB.22.11.3565-3576.2002  1
2002 Kryukov GV, Kumar RA, Koc A, Sun Z, Gladyshev VN. Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proceedings of the National Academy of Sciences of the United States of America. 99: 4245-50. PMID 11929995 DOI: 10.1073/pnas.072603099  1
2002 Gladyshev VN. Comparison of selenium-containing molybdoenzymes Metal Ions in Biological Systems. 39: 655-672. PMID 11913139  1
2002 Kryukov GV, Gladyshev VN. Mammalian selenoprotein gene signature: identification and functional analysis of selenoprotein genes using bioinformatics methods. Methods in Enzymology. 347: 84-100. PMID 11898441 DOI: 10.1016/S0076-6879(02)47010-3  1
2002 Sun QA, Gladyshev VN. Redox regulation of cell signaling by thioredoxin reductases. Methods in Enzymology. 347: 451-61. PMID 11898437 DOI: 10.1016/S0076-6879(02)47045-0  1
2002 Kumaraswamy E, Korotkov KV, Diamond AM, Gladyshev VN, Hatfield DL. Genetic and functional analysis of mammalian Sep15 selenoprotein. Methods in Enzymology. 347: 187-97. PMID 11898406 DOI: 10.1016/S0076-6879(02)47017-6  1
2002 Korotkov KV, Novoselov SV, Hatfield DL, Gladyshev VN. Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element Molecular and Cellular Biology. 22: 1402-1411. PMID 11839807 DOI: 10.1128/MCB.22.5.1402-1411.2002  1
2002 Gladyshev VN. Thioredoxin and peptide methionine sulfoxide reductase: Convergence of similar structure and function in distinct structural folds Proteins: Structure, Function and Genetics. 46: 149-152. PMID 11807942 DOI: 10.1002/prot.10003  1
2001 Gladyshev VN, Hatfield DL. Analysis of selenocysteine-containing proteins Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. PMID 18429173  1
2001 Gladyshev VN, Kryukov GV. Evolution of selenocysteine-containing proteins: significance of identification and functional characterization of selenoproteins. Biofactors (Oxford, England). 14: 87-92. PMID 11568444  1
2001 Gladyshev VN, Liu A, Novoselov SV, Krysan K, Sun QA, Kryukov VM, Kryukov GV, Lou MF. Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. The Journal of Biological Chemistry. 276: 30374-80. PMID 11397793 DOI: 10.1074/jbc.M100020200  1
2001 Martin-Romero FJ, Kryukov GV, Lobanov AV, Carlson BA, Lee BJ, Gladyshev VN, Hatfield DL. Selenium metabolism in Drosophila: selenoproteins, selenoprotein mRNA expression, fertility, and mortality. The Journal of Biological Chemistry. 276: 29798-804. PMID 11389138 DOI: 10.1074/jbc.M100422200  1
2001 Moustafa ME, Carlson BA, El-Saadani MA, Kryukov GV, Sun QA, Harney JW, Hill KE, Combs GF, Feigenbaum L, Mansur DB, Burk RF, Berry MJ, Diamond AM, Lee BJ, Gladyshev VN, et al. Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA. Molecular and Cellular Biology. 21: 3840-52. PMID 11340175 DOI: 10.1128/MCB.21.11.3840-3852.2001  1
2001 Korotkov KV, Kumaraswamy E, Zhou Y, Hatfield DL, Gladyshev VN. Association between the 15-kDa Selenoprotein and UDP-glucose:Glycoprotein Glucosyltransferase in the Endoplasmic Reticulum of Mammalian Cells Journal of Biological Chemistry. 276: 15330-15336. PMID 11278576 DOI: 10.1074/jbc.M009861200  1
2001 Sun QA, Kirnarsky L, Sherman S, Gladyshev VN. Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Proceedings of the National Academy of Sciences of the United States of America. 98: 3673-8. PMID 11259642 DOI: 10.1073/pnas.051454398  1
2001 Sun QA, Zappacosta F, Factor VM, Wirth PJ, Hatfield DL, Gladyshev VN. Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing. The Journal of Biological Chemistry. 276: 3106-14. PMID 11060283 DOI: 10.1074/jbc.M004750200  1
2000 Kryukov GV, Gladyshev VN. Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 5: 1049-60. PMID 11168591 DOI: 10.1046/j.1365-2443.2000.00392.x  1
1999 Kryukov GV, Kryukov VM, Gladyshev VN. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements. The Journal of Biological Chemistry. 274: 33888-97. PMID 10567350 DOI: 10.1074/jbc.274.48.33888  1
1999 Sun QA, Wu Y, Zappacosta F, Jeang KT, Lee BJ, Hatfield DL, Gladyshev VN. Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases. The Journal of Biological Chemistry. 274: 24522-30. PMID 10455115  0.96
1999 Gladyshev VN, Krause M, Xu XM, Korotkov KV, Kryukov GV, Sun QA, Lee BJ, Wootton JC, Hatfield DL. Selenocysteine-containing thioredoxin reductase in C. elegans. Biochemical and Biophysical Research Communications. 259: 244-9. PMID 10362494 DOI: 10.1006/bbrc.1999.0765  1
1999 Gladyshev VN, Hatfield DL. Selenocysteine-containing proteins in mammals Journal of Biomedical Science. 6: 151-160. PMID 10343164  1
1999 Gladyshev VN, Stadtman TC, Hatfield DL, Jeang KT. Levels of major selenoproteins in T cells decrease during HIV infection and low molecular mass selenium compounds increase Proceedings of the National Academy of Sciences of the United States of America. 96: 835-839. PMID 9927654 DOI: 10.1073/pnas.96.3.835  1
1998 Gladyshev VN, Factor VM, Housseau F, Hatfield DL. Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells Biochemical and Biophysical Research Communications. 251: 488-493. PMID 9792801 DOI: 10.1006/bbrc.1998.9495  1
1998 Gladyshev VN, Jeang KT, Wootton JC, Hatfield DL. A new human selenium-containing protein. Purification, characterization, and cDNA sequence Journal of Biological Chemistry. 273: 8910-8915. PMID 9535873 DOI: 10.1074/jbc.273.15.8910  1
1998 Khangulov SV, Gladyshev VN, Charles Dismukes G, Stadtman TC. Selenium-containing formate dehydrogenase H from Escherichia coli: A molybdopterin enzyme that catalyses formate oxidation without oxygen transfer Biochemistry. 37: 3518-3528. PMID 9521673 DOI: 10.1021/bi972177k  1
1998 George GN, Colangelo CM, Dong J, Scott RA, Khangulov SV, Gladyshev VN, Stadtman TC. X-ray absorption spectroscopy of the molybdenum site of escherichia coli formate dehydrogenase Journal of the American Chemical Society. 120: 1267-1273. DOI: 10.1021/ja973004l  1
1997 Boyington JC, Gladyshev VN, Khangulov SV, Stadtman TC, Sun PD. Crystal structure of formate dehydrogenase H: Catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster Science. 275: 1305-1308. PMID 9036855 DOI: 10.1126/science.275.5304.1305  1
1997 Gladyshev VN, Jeang KT, Hatfield DL, Stadtman TC. Selenium in normal and HIV-infected human T cells: Discovery of a novel selenoprotein Faseb Journal. 11: A235.  1
1997 Klyachko NL, Vakula SV, Gladyshev VN, Tishkov VI, Levashov AV. Formate dehydrogenase in a reversed micelle system: Regulation of catalytic activity and oligomeric composition of the enzyme Biochemistry (Moscow). 62: 1439-1443.  1
1996 Gladyshev VN, Jeang KT, Stadtman TC. Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene Proceedings of the National Academy of Sciences of the United States of America. 93: 6146-6151. PMID 8650234 DOI: 10.1073/pnas.93.12.6146  1
1996 Gladyshev VN, Boyington JC, Khangulov SV, Grahame DA, Stadtman TC, Sun PD. Characterization of crystalline formate dehydrogenase H from Escherichia coli: Stabilization, EPR spectroscopy, and preliminary crystallographic analysis Journal of Biological Chemistry. 271: 8095-8100. PMID 8626495  1
1996 Gladyshev VN, Khangulov SV, Stadtman TC. Properties of the selenium- and molybdenum-containing nicotinic acid hydroxylase from Clostridium barkeri Biochemistry. 35: 212-223. PMID 8555176 DOI: 10.1021/bi951793i  1
1995 Gladyshev VN, Lecchi P. Identification of molybdopterins in molybdenum- and selenium-containing enzymes Biofactors. 5: 93-97. PMID 8722123  1
1994 Gladyshev VN, Khangulov SV, Stadtman TC. Nicotinic acid hydroxylase from Clostridium barkeri: Electron paramagnetic resonance studies show that selenium is coordinated with molybdenum in the catalytically active selenium-dependent enzyme Proceedings of the National Academy of Sciences of the United States of America. 91: 232-236. PMID 8278371 DOI: 10.1073/pnas.91.1.232  1
1994 Gladyshev VN, Khangulov SV, Axley MJ, Stadtman TC. Coordination of selenium to molybdenum in formate dehydrogenase H from Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 91: 7708-7711. PMID 8052647 DOI: 10.1073/pnas.91.16.7708  1
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