Aziz Sancar - Publications

Affiliations: 
Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
DNA Repair
Website:
http://www.med.unc.edu/biochem/asancar

233 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Deger N, Yang Y, Lindsey-Boltz LA, Sancar A, Selby CP. , which Lacks Canonical Transcription-Coupled Repair Proteins, Performs Transcription-Coupled Repair. The Journal of Biological Chemistry. PMID 31624146 DOI: 10.1074/jbc.AC119.011448  0.76
2019 Yang Y, Liu Z, Selby CP, Sancar A. Long-term, genome-wide kinetic analysis of the effect of the circadian clock and transcription on the repair of cisplatin-DNA adducts in the mouse liver. The Journal of Biological Chemistry. PMID 31217280 DOI: 10.1074/jbc.RA119.009579  0.76
2019 Li W, Liu W, Kakoki A, Wang R, Adebali O, Jiang Y, Sancar A. Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells. The Journal of Biological Chemistry. PMID 30808711 DOI: 10.1074/jbc.RA119.007861  0.76
2019 Yimit A, Adebali O, Sancar A, Jiang Y. Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs. Nature Communications. 10: 309. PMID 30659176 DOI: 10.1038/s41467-019-08290-2  0.76
2018 Hu J, Li W, Adebali O, Yang Y, Oztas O, Selby CP, Sancar A. Genome-wide mapping of nucleotide excision repair with XR-seq. Nature Protocols. PMID 30552409 DOI: 10.1038/s41596-018-0093-7  0.76
2018 Yang Y, Hu J, Selby CP, Li W, Yimit A, Jiang Y, Sancar A. Single nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and mice. The Journal of Biological Chemistry. PMID 30413533 DOI: 10.1074/jbc.RA118.006121  0.76
2018 Wang X, Jing C, Selby CP, Chiou YY, Yang Y, Wu W, Sancar A, Wang J. Comparative properties and functions of type 2 and type 4 pigeon cryptochromes. Cellular and Molecular Life Sciences : Cmls. PMID 30264181 DOI: 10.1007/s00018-018-2920-y  0.76
2018 Yang Y, Adebali O, Wu G, Selby CP, Chiou YY, Rashid N, Hu J, Hogenesch JB, Sancar A. Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse tissues. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735688 DOI: 10.1073/pnas.1804493115  0.76
2018 Oztas O, Selby CP, Sancar A, Adebali O. Genome-wide excision repair in Arabidopsis is coupled to transcription and reflects circadian gene expression patterns. Nature Communications. 9: 1503. PMID 29666379 DOI: 10.1038/s41467-018-03922-5  0.76
2018 Li W, Adebali O, Yang Y, Selby CP, Sancar A. Single-nucleotide resolution dynamic repair maps of UV damage ingenome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581276 DOI: 10.1073/pnas.1801687115  0.76
2017 Chiou YY, Hu J, Sancar A, Selby CP. RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian cells. The Journal of Biological Chemistry. PMID 29282293 DOI: 10.1074/jbc.RA117.000971  0.76
2017 Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, ... ... Sancar A, et al. Guidelines for Genome-Scale Analysis of Biological Rhythms. Journal of Biological Rhythms. 748730417728663. PMID 29098954 DOI: 10.1177/0748730417728663  0.4
2017 Adebali O, Sancar A, Selby CP. Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli. The Journal of Biological Chemistry. PMID 28986449 DOI: 10.1074/jbc.C117.818807  0.76
2017 Hu J, Selby CP, Adar S, Adebali O, Sancar A. Molecular mechanisms and genomic maps of DNA excision repair in E.coli and humans. The Journal of Biological Chemistry. PMID 28798238 DOI: 10.1074/jbc.R117.807453  0.76
2017 Hu J, Adebali O, Adar S, Sancar A. Dynamic maps of UV damage formation and repair for the human genome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607063 DOI: 10.1073/pnas.1706522114  0.76
2017 Li W, Hu J, Adebali O, Adar S, Yang Y, Chiou YY, Sancar A. Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607059 DOI: 10.1073/pnas.1706021114  0.76
2017 Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, ... ... Sancar A, et al. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metabolism. 25: 1206. PMID 28467936 DOI: 10.1016/j.cmet.2017.04.023  0.76
2017 Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, ... ... Sancar A, et al. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metabolism. 25: 961-974.e4. PMID 28380384 DOI: 10.1016/j.cmet.2017.03.019  0.76
2017 Adebali O, Chiou YY, Hu J, Sancar A, Selby CP. Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28167766 DOI: 10.1073/pnas.1700230114  0.76
2017 Sancar A, Zhong D. It Is Chemistry but Not Your Grandfather's Chemistry. Biochemistry. 56: 1-2. PMID 28068777 DOI: 10.1021/acs.biochem.6b01262  0.72
2016 Zhang M, Wang L, Shu S, Sancar A, Zhong D. Bifurcating electron-transfer pathways in DNA photolyases determine the repair quantum yield. Science (New York, N.Y.). 354: 209-213. PMID 27738168 DOI: 10.1126/science.aah6071  1
2016 Hu J, Lieb JD, Sancar A, Adar S. Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution. Proceedings of the National Academy of Sciences of the United States of America. PMID 27688757 DOI: 10.1073/pnas.1614430113  0.52
2016 Chiou YY, Yang Y, Rashid N, Ye R, Selby CP, Sancar A. Mammalian Period represses and de-represses transcription by displacing CLOCK-BMAL1 from promoters in a Cryptochrome-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. PMID 27688755 DOI: 10.1073/pnas.1612917113  0.76
2016 Jang H, Lee GY, Selby CP, Lee G, Jeon YG, Lee JH, Cheng KK, Titchenell P, Birnbaum MJ, Xu A, Sancar A, Kim JB. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nature Communications. 7: 12180. PMID 27412556 DOI: 10.1038/ncomms12180  1
2016 Canturk F, Karaman M, Selby CP, Kemp MG, Kulaksiz-Erkmen G, Hu J, Li W, Lindsey-Boltz LA, Sancar A. Nucleotide excision repair by dual incisions in plants. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071131 DOI: 10.1073/pnas.1604097113  0.76
2016 Adar S, Hu J, Lieb JD, Sancar A. Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27036006 DOI: 10.1073/pnas.1603388113  0.52
2016 Kemp MG, Sancar A. ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. The Journal of Biological Chemistry. PMID 26940878 DOI: 10.1074/jbc.M116.719740  0.52
2015 Lindsey-Boltz LA, Kemp MG, Hu J, Sancar A. Analysis of ribonucleotide removal from DNA by human nucleotide excision repair. The Journal of Biological Chemistry. PMID 26491008 DOI: 10.1074/jbc.M115.695254  0.48
2015 Choi JH, Kim SY, Kim SK, Kemp MG, Sancar A. An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: Nucleotide Excision Repair, DNA Damage Checkpoint, and Apoptosis. The Journal of Biological Chemistry. PMID 26438822 DOI: 10.1074/jbc.M115.690354  0.48
2015 Tan C, Liu Z, Li J, Guo X, Wang L, Sancar A, Zhong D. The molecular origin of high DNA-repair efficiency by photolyase. Nature Communications. 6: 7302. PMID 26065359 DOI: 10.1038/ncomms8302  1
2015 Hu J, Adar S, Selby CP, Lieb JD, Sancar A. Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution. Genes & Development. 29: 948-60. PMID 25934506 DOI: 10.1101/gad.261271.115  0.76
2015 Kemp MG, Lindsey-Boltz LA, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). The Journal of Biological Chemistry. 290: 12184-94. PMID 25792739 DOI: 10.1074/jbc.M115.649301  0.56
2015 Lindsey-Boltz LA, Kemp MG, Capp C, Sancar A. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling. Cell Cycle (Georgetown, Tex.). 14: 99-108. PMID 25602520 DOI: 10.4161/15384101.2014.967076  0.56
2015 Gaddameedhi S, Selby CP, Kemp MG, Ye R, Sancar A. The circadian clock controls sunburn apoptosis and erythema in mouse skin. The Journal of Investigative Dermatology. 135: 1119-27. PMID 25431853 DOI: 10.1038/jid.2014.508  0.76
2015 Sancar A, Lindsey-Boltz LA, Gaddameedhi S, Selby CP, Ye R, Chiou YY, Kemp MG, Hu J, Lee JH, Ozturk N. Circadian clock, cancer, and chemotherapy. Biochemistry. 54: 110-23. PMID 25302769 DOI: 10.1021/bi5007354  0.76
2015 Lindsey-Boltz LA, Kemp MG, Capp C, Sancar A. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling http://www.tandfonline.com/doi/pdf/10.4161/15384101.2014.967076 Cell Cycle. 14: 99-108. DOI: 10.4161/15384101.2014.967076  1
2015 Kemp MG, Lindsey-Boltz LA, Sancar A. UV light potentiates STING (stimulator of interferon genes)-dependent innate immune signaling through deregulation of ULK1 (Unc51-like kinase 1) Journal of Biological Chemistry. 290: 12184-12194. DOI: 10.1074/jbc.M115.649301  1
2015 Gaddameedhi S, Selby CP, Kemp MG, Ye R, Sancar A. The Circadian Clock Controls Sunburn Apoptosis and Erythema in Mouse Skin Journal of Investigative Dermatology. 135: 1119-1127. DOI: 10.1038/jid.2014.508  1
2015 Sancar A, Lindsey-Boltz LA, Gaddameedhi S, Selby CP, Ye R, Chiou YY, Kemp MG, Hu J, Lee JH, Ozturk N. Circadian clock, cancer, and chemotherapy Biochemistry. 54: 110-123. DOI: 10.1021/bi5007354  1
2015 Hu J, Adar S, Selby CP, Lieb JD, Sancar A. Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution Genes and Development. 29: 948-960.  1
2014 Ye R, Selby CP, Chiou YY, Ozkan-Dagliyan I, Gaddameedhi S, Sancar A. Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock. Genes & Development. 28: 1989-98. PMID 25228643 DOI: 10.1101/gad.249417.114  1
2014 Kemp MG, Gaddameedhi S, Choi JH, Hu J, Sancar A. DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. The Journal of Biological Chemistry. 289: 26574-83. PMID 25107903 DOI: 10.1074/jbc.M114.597088  1
2014 Tan C, Guo L, Ai Y, Li J, Wang L, Sancar A, Luo Y, Zhong D. Direct determination of resonance energy transfer in photolyase: structural alignment for the functional state. The Journal of Physical Chemistry. A. 118: 10522-30. PMID 25000823 DOI: 10.1021/jp504349b  0.72
2014 Lindsey-Boltz LA, Kemp MG, Reardon JT, DeRocco V, Iyer RR, Modrich P, Sancar A. Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system. The Journal of Biological Chemistry. 289: 5074-82. PMID 24403078 DOI: 10.1074/jbc.M113.542787  1
2014 Annayev Y, Adar S, Chiou YY, Lieb JD, Sancar A, Ye R. Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression. The Journal of Biological Chemistry. 289: 5013-24. PMID 24385426 DOI: 10.1074/jbc.M113.534651  1
2014 Ozturk N, Selby CP, Zhong D, Sancar A. Mechanism of photosignaling by Drosophila cryptochrome: role of the redox status of the flavin chromophore. The Journal of Biological Chemistry. 289: 4634-42. PMID 24379403 DOI: 10.1074/jbc.M113.542498  1
2014 Choi JH, Gaddameedhi S, Kim SY, Hu J, Kemp MG, Sancar A. Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells. Nucleic Acids Research. 42: e29. PMID 24271390 DOI: 10.1093/nar/gkt1179  1
2014 Tan C, Guo L, Ai Y, Li J, Wang L, Sancar A, Luo Y, Zhong D. Direct determination of resonance energy transfer in photolyase: Structural alignment for the functional state Journal of Physical Chemistry A. 118: 10522-10530. DOI: 10.1021/jp504349b  1
2013 Liu Z, Tan C, Guo X, Li J, Wang L, Sancar A, Zhong D. Determining complete electron flow in the cofactor photoreduction of oxidized photolyase. Proceedings of the National Academy of Sciences of the United States of America. 110: 12966-71. PMID 23882080 DOI: 10.1073/pnas.1311073110  1
2013 Liu Z, Zhang M, Guo X, Tan C, Li J, Wang L, Sancar A, Zhong D. Dynamic determination of the functional state in photolyase and the implication for cryptochrome. Proceedings of the National Academy of Sciences of the United States of America. 110: 12972-7. PMID 23882072 DOI: 10.1073/pnas.1311077110  1
2013 Ozkan-Dagliyan I, Chiou YY, Ye R, Hassan BH, Ozturk N, Sancar A. Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch. The Journal of Biological Chemistry. 288: 23244-51. PMID 23833191 DOI: 10.1074/jbc.M113.493361  1
2013 Hu J, Choi JH, Gaddameedhi S, Kemp MG, Reardon JT, Sancar A. Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo. The Journal of Biological Chemistry. 288: 20918-26. PMID 23749995 DOI: 10.1074/jbc.M113.482257  1
2013 Hassan BH, Lindsey-Boltz LA, Kemp MG, Sancar A. Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response. The Journal of Biological Chemistry. 288: 18903-10. PMID 23696651 DOI: 10.1074/jbc.M113.475517  1
2013 Ozturk N, VanVickle-Chavez SJ, Akileswaran L, Van Gelder RN, Sancar A. Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 4980-5. PMID 23479607 DOI: 10.1073/pnas.1303234110  1
2013 Lee JH, Gaddameedhi S, Ozturk N, Ye R, Sancar A. DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells. Cancer Research. 73: 785-91. PMID 23149912 DOI: 10.1158/0008-5472.CAN-12-1994  1
2012 Lindsey-Boltz LA, Reardon JT, Wold MS, Sancar A. In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling. The Journal of Biological Chemistry. 287: 36123-31. PMID 22948311 DOI: 10.1074/jbc.M112.407825  1
2012 Gaddameedhi S, Reardon JT, Ye R, Ozturk N, Sancar A. Effect of circadian clock mutations on DNA damage response in mammalian cells. Cell Cycle (Georgetown, Tex.). 11: 3481-91. PMID 22918252 DOI: 10.4161/cc.21771  1
2012 Kemp MG, Sancar A. DNA excision repair: where do all the dimers go? Cell Cycle (Georgetown, Tex.). 11: 2997-3002. PMID 22825251 DOI: 10.4161/cc.21126  1
2012 Kemp MG, Reardon JT, Lindsey-Boltz LA, Sancar A. Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair. The Journal of Biological Chemistry. 287: 22889-99. PMID 22573372 DOI: 10.1074/jbc.M112.374447  1
2012 Liu Z, Guo X, Tan C, Li J, Kao YT, Wang L, Sancar A, Zhong D. Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase. Journal of the American Chemical Society. 134: 8104-14. PMID 22533849 DOI: 10.1021/ja2105009  1
2012 Rivera AS, Ozturk N, Fahey B, Plachetzki DC, Degnan BM, Sancar A, Oakley TH. Blue-light-receptive cryptochrome is expressed in a sponge eye lacking neurons and opsin. The Journal of Experimental Biology. 215: 1278-86. PMID 22442365 DOI: 10.1242/jeb.067140  1
2012 Selby CP, Sancar A. The second chromophore in Drosophila photolyase/cryptochrome family photoreceptors. Biochemistry. 51: 167-71. PMID 22175817 DOI: 10.1021/bi201536w  1
2012 Zhong D, Sancar A, Stuchebrukhov A. Reply to Brettel and Byrdin: On the efficiency of DNA repair by photolyase Proceedings of the National Academy of Sciences of the United States of America. 109: E1463. DOI: 10.1073/pnas.1204602109  1
2011 Gaddameedhi S, Selby CP, Kaufmann WK, Smart RC, Sancar A. Control of skin cancer by the circadian rhythm. Proceedings of the National Academy of Sciences of the United States of America. 108: 18790-5. PMID 22025708 DOI: 10.1073/pnas.1115249108  1
2011 Yilmaz S, Sancar A, Kemp MG. Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates. Plos One. 6: e22986. PMID 21829571 DOI: 10.1371/journal.pone.0022986  1
2011 Liu Z, Tan C, Guo X, Kao YT, Li J, Wang L, Sancar A, Zhong D. Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase. Proceedings of the National Academy of Sciences of the United States of America. 108: 14831-6. PMID 21804035 DOI: 10.1073/pnas.1110927108  1
2011 Lee JH, Sancar A. Regulation of apoptosis by the circadian clock through NF-kappaB signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: 12036-41. PMID 21690409 DOI: 10.1073/pnas.1108125108  1
2011 Lee JH, Sancar A. Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 108: 10668-72. PMID 21628572 DOI: 10.1073/pnas.1106284108  1
2011 Ye R, Selby CP, Ozturk N, Annayev Y, Sancar A. Biochemical analysis of the canonical model for the mammalian circadian clock. The Journal of Biological Chemistry. 286: 25891-902. PMID 21613214 DOI: 10.1074/jbc.M111.254680  1
2011 Lindsey-Boltz LA, Sancar A. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1). The Journal of Biological Chemistry. 286: 19229-36. PMID 21502314 DOI: 10.1074/jbc.M111.237958  1
2011 Kemp MG, Lindsey-Boltz LA, Sancar A. The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA. The Journal of Biological Chemistry. 286: 19237-46. PMID 21487018 DOI: 10.1074/jbc.M111.235036  1
2011 Kang TH, Reardon JT, Sancar A. Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein. Nucleic Acids Research. 39: 3176-87. PMID 21193487 DOI: 10.1093/nar/gkq1318  1
2011 Ozturk N, Selby CP, Annayev Y, Zhong D, Sancar A. Reaction mechanism of Drosophila cryptochrome. Proceedings of the National Academy of Sciences of the United States of America. 108: 516-21. PMID 21187431 DOI: 10.1073/pnas.1017093108  1
2011 Beharry Z, Mahajan S, Zemskova M, Lin YW, Tholanikunnel BG, Xia Z, Smith CD, Kraft AS. The Pim protein kinases regulate energy metabolism and cell growth. Proceedings of the National Academy of Sciences of the United States of America. 108: 528-33. PMID 21187426 DOI: 10.1073/pnas.1013214108  1
2011 Gaddameedhi S, Sancar A. Melanoma and DNA damage from a distance (farstander effect). Pigment Cell & Melanoma Research. 24: 3-4. PMID 21073665 DOI: 10.1111/j.1755-148X.2010.00805.x  1
2010 Li J, Liu Z, Tan C, Guo X, Wang L, Sancar A, Zhong D. Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase. Nature. 466: 887-890. PMID 20657578 DOI: 10.1038/nature09192  1
2010 Choi JH, Lindsey-Boltz LA, Kemp M, Mason AC, Wold MS, Sancar A. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 13660-5. PMID 20616048 DOI: 10.1073/pnas.1007856107  1
2010 Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Research. 70: 4922-30. PMID 20501836 DOI: 10.1158/0008-5472.CAN-10-0095  1
2010 Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A. Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 107: 4890-5. PMID 20304803 DOI: 10.1073/pnas.0915085107  1
2010 Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kaçmaz K. Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. The Journal of Biological Chemistry. 285: 16562-71. PMID 20233725 DOI: 10.1074/jbc.M110.110304  1
2010 Sancar A, Lindsey-Boltz LA, Kang TH, Reardon JT, Lee JH, Ozturk N. Circadian clock control of the cellular response to DNA damage. Febs Letters. 584: 2618-25. PMID 20227409 DOI: 10.1016/j.febslet.2010.03.017  1
2010 Chang CW, Guo L, Kao YT, Li J, Tan C, Li T, Saxena C, Liu Z, Wang L, Sancar A, Zhong D. Ultrafast solvation dynamics at binding and active sites of photolyases. Proceedings of the National Academy of Sciences of the United States of America. 107: 2914-9. PMID 20133751 DOI: 10.1073/pnas.1000001107  1
2010 Liu Y, Fang Y, Shao H, Lindsey-Boltz L, Sancar A, Modrich P. Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. The Journal of Biological Chemistry. 285: 5974-82. PMID 20029092 DOI: 10.1074/jbc.M109.076109  1
2010 Kemp MG, Mason AC, Carreira A, Reardon JT, Haring SJ, Borgstahl GE, Kowalczykowski SC, Sancar A, Wold MS. An alternative form of replication protein a expressed in normal human tissues supports DNA repair. The Journal of Biological Chemistry. 285: 4788-97. PMID 19996105 DOI: 10.1074/jbc.M109.079418  1
2009 Kemp M, Sancar A. DNA distress: just ring 9-1-1. Current Biology : Cb. 19: R733-4. PMID 19833574 DOI: 10.1016/j.cub.2009.07.026  1
2009 Lindsey-Boltz LA, Serçin O, Choi JH, Sancar A. Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase. The Journal of Biological Chemistry. 284: 33107-14. PMID 19828454 DOI: 10.1074/jbc.M109.064485  1
2009 Ozturk N, Selby CP, Song SH, Ye R, Tan C, Kao YT, Zhong D, Sancar A. Comparative photochemistry of animal type 1 and type 4 cryptochromes. Biochemistry. 48: 8585-93. PMID 19663499 DOI: 10.1021/bi901043s  1
2009 Li L, Perdigao J, Pegg AE, Lao Y, Hecht SS, Lindgren BR, Reardon JT, Sancar A, Wattenberg EV, Peterson LA. The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines. Chemical Research in Toxicology. 22: 1464-72. PMID 19601657 DOI: 10.1021/tx9001572  1
2009 Kang TH, Sancar A. Circadian regulation of DNA excision repair: implications for chrono-chemotherapy. Cell Cycle (Georgetown, Tex.). 8: 1665-7. PMID 19411851  1
2009 Balakrishnan L, Brandt PD, Lindsey-Boltz LA, Sancar A, Bambara RA. Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex. The Journal of Biological Chemistry. 284: 15158-72. PMID 19329425 DOI: 10.1074/jbc.M109.000505  1
2009 Choi JH, Sancar A, Lindsey-Boltz LA. The human ATR-mediated DNA damage checkpoint in a reconstituted system. Methods (San Diego, Calif.). 48: 3-7. PMID 19245835 DOI: 10.1016/j.ymeth.2009.02.006  1
2009 Ozturk N, Lee JH, Gaddameedhi S, Sancar A. Loss of cryptochrome reduces cancer risk in p53 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 2841-6. PMID 19188586 DOI: 10.1073/pnas.0813028106  1
2009 Kang TH, Reardon JT, Kemp M, Sancar A. Circadian oscillation of nucleotide excision repair in mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 106: 2864-7. PMID 19164551 DOI: 10.1073/pnas.0812638106  1
2009 Choi JH, Lindsey-Boltz LA, Sancar A. Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA. Nucleic Acids Research. 37: 1501-9. PMID 19139065 DOI: 10.1093/nar/gkn1075  1
2008 Oztürk N, Kao YT, Selby CP, Kavakli IH, Partch CL, Zhong D, Sancar A. Purification and characterization of a type III photolyase from Caulobacter crescentus. Biochemistry. 47: 10255-61. PMID 18771290 DOI: 10.1021/bi801085a  1
2008 Kao YT, Saxena C, He TF, Guo L, Wang L, Sancar A, Zhong D. Ultrafast dynamics of flavins in five redox states. Journal of the American Chemical Society. 130: 13132-9. PMID 18767842 DOI: 10.1021/ja8045469  1
2008 Sancar A. Structure and function of photolyase and in vivo enzymology: 50th anniversary. The Journal of Biological Chemistry. 283: 32153-7. PMID 18682397 DOI: 10.1074/jbc.R800052200  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7193-201. PMID 18614689 DOI: 10.1523/JNEUROSCI.1150-08.2008  1
2008 Lovejoy KS, Todd RC, Zhang S, McCormick MS, D'Aquino JA, Reardon JT, Sancar A, Giacomini KM, Lippard SJ. cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proceedings of the National Academy of Sciences of the United States of America. 105: 8902-7. PMID 18579768 DOI: 10.1073/pnas.0803441105  1
2008 Kao YT, Tan C, Song SH, Oztürk N, Li J, Wang L, Sancar A, Zhong D. Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase. Journal of the American Chemical Society. 130: 7695-701. PMID 18500802 DOI: 10.1021/ja801152h  1
2008 Sancar A. The intelligent clock and the Rube Goldberg clock. Nature Structural & Molecular Biology. 15: 23-4. PMID 18176552 DOI: 10.1038/nsmb0108-23  1
2008 Oztürk N, Song SH, Selby CP, Sancar A. Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis. The Journal of Biological Chemistry. 283: 3256-63. PMID 18056988 DOI: 10.1074/jbc.M708612200  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains (Journal of Neuroscience (July 9, 2008) (7193-7201)) Journal of Neuroscience. 28: 7929.  1
2007 Oztürk N, Song SH, Ozgür S, Selby CP, Morrison L, Partch C, Zhong D, Sancar A. Structure and function of animal cryptochromes. Cold Spring Harbor Symposia On Quantitative Biology. 72: 119-31. PMID 18419269 DOI: 10.1101/sqb.2007.72.015  1
2007 Kesseler KJ, Kaufmann WK, Reardon JT, Elston TC, Sancar A. A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading. Journal of Theoretical Biology. 249: 361-75. PMID 17869273 DOI: 10.1016/j.jtbi.2007.07.025  1
2007 Kao YT, Saxena C, Wang L, Sancar A, Zhong D. Femtochemistry in enzyme catalysis: DNA photolyase. Cell Biochemistry and Biophysics. 48: 32-44. PMID 17703066 DOI: 10.1007/s12013-007-0034-5  1
2007 Choi JH, Lindsey-Boltz LA, Sancar A. Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Proceedings of the National Academy of Sciences of the United States of America. 104: 13301-6. PMID 17686975 DOI: 10.1073/pnas.0706013104  1
2007 Lindsey-Boltz LA, Sancar A. RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage? Proceedings of the National Academy of Sciences of the United States of America. 104: 13213-4. PMID 17684092 DOI: 10.1073/pnas.0706316104  1
2007 Song SH, Oztürk N, Denaro TR, Arat NO, Kao YT, Zhu H, Zhong D, Reppert SM, Sancar A. Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly. The Journal of Biological Chemistry. 282: 17608-12. PMID 17459876 DOI: 10.1074/jbc.M702874200  1
2007 Sokolova O, Cecala C, Gopal A, Cortazar F, McDowell-Buchanan C, Sancar A, Gindt YM, Schelvis JP. Resonance Raman spectroscopic investigation of the light-harvesting chromophore in escherichia coli photolyase and Vibrio cholerae cryptochrome-1. Biochemistry. 46: 3673-81. PMID 17316023 DOI: 10.1021/bi602385j  1
2007 Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK. The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Molecular and Cellular Biology. 27: 3131-42. PMID 17296725 DOI: 10.1128/MCB.02190-06  1
2007 Heffernan TP, Unsal-Kaçmaz K, Heinloth AN, Simpson DA, Paules RS, Sancar A, Cordeiro-Stone M, Kaufmann WK. Cdc7-Dbf4 and the human S checkpoint response to UVC. The Journal of Biological Chemistry. 282: 9458-68. PMID 17276990 DOI: 10.1074/jbc.M611292200  1
2006 Roberts RB, Thompson CL, Lee D, Mankinen RW, Sancar A, Threadgill DW. Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice. Journal of Circadian Rhythms. 4: 15. PMID 17109754 DOI: 10.1186/1740-3391-4-15  0.88
2006 Ozgür S, Sancar A. Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes. Biochemistry. 45: 13369-74. PMID 17073458 DOI: 10.1021/bi061556n  1
2006 Selby CP, Sancar A. A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 17696-700. PMID 17062752 DOI: 10.1073/pnas.0607993103  1
2006 Reardon JT, Sancar A. Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems. Methods in Enzymology. 408: 189-213. PMID 16793370 DOI: 10.1016/S0076-6879(06)08012-8  1
2006 Sancar GB, Sancar A. Purification and characterization of DNA photolyases. Methods in Enzymology. 408: 121-56. PMID 16793367 DOI: 10.1016/S0076-6879(06)08009-8  1
2006 Partch CL, Shields KF, Thompson CL, Selby CP, Sancar A. Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5. Proceedings of the National Academy of Sciences of the United States of America. 103: 10467-72. PMID 16790549 DOI: 10.1073/pnas.0604138103  1
2006 Reardon JT, Cheng Y, Sancar A. Repair of DNA-protein cross-links in mammalian cells. Cell Cycle (Georgetown, Tex.). 5: 1366-70. PMID 16775425  1
2006 Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA. Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. The Journal of Biological Chemistry. 281: 20865-72. PMID 16731526 DOI: 10.1074/jbc.M602289200  1
2006 Reardon JT, Sancar A. Repair of DNA-polypeptide crosslinks by human excision nuclease. Proceedings of the National Academy of Sciences of the United States of America. 103: 4056-61. PMID 16537484 DOI: 10.1073/pnas.0600538103  1
2006 Jiang G, Sancar A. Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences. Molecular and Cellular Biology. 26: 39-49. PMID 16354678 DOI: 10.1128/MCB.26.1.39-49.2006  1
2006 Roberts RB, Thompson CL, Lee D, Mankinen RW, Sancar A, Threadgill DW. Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice Journal of Circadian Rhythms. 4. DOI: 10.1186/1740-3391-4-15  1
2006 Saxena C, Kao YT, Wang L, Sancar A, Zhong D. Direct observation of DNA repair by photolyase Femtochemistry Vii. 407-410. DOI: 10.1016/B978-044452821-6/50059-9  1
2005 Wang H, Saxena C, Quan D, Sancar A, Zhong D. Femtosecond dynamics of flavin cofactor in DNA photolyase: radical reduction, local solvation, and charge recombination. The Journal of Physical Chemistry. B. 109: 1329-33. PMID 16851098 DOI: 10.1021/jp044652b  1
2005 Kulaksiz G, Reardon JT, Sancar A. Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties. Molecular and Cellular Biology. 25: 9784-92. PMID 16260596 DOI: 10.1128/MCB.25.22.9784-9792.2005  1
2005 Kao YT, Saxena C, Wang L, Sancar A, Zhong D. Direct observation of thymine dimer repair in DNA by photolyase. Proceedings of the National Academy of Sciences of the United States of America. 102: 16128-32. PMID 16169906 DOI: 10.1073/pnas.0506586102  1
2005 Partch CL, Sancar A. Photochemistry and photobiology of cryptochrome blue-light photopigments: the search for a photocycle. Photochemistry and Photobiology. 81: 1291-304. PMID 16164372 DOI: 10.1562/2005-07-08-IR-607  1
2005 Reardon JT, Sancar A. Nucleotide excision repair. Progress in Nucleic Acid Research and Molecular Biology. 79: 183-235. PMID 16096029 DOI: 10.1016/S0079-6603(04)79004-2  1
2005 Gauger MA, Sancar A. Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer. Cancer Research. 65: 6828-34. PMID 16061665 DOI: 10.1158/0008-5472.CAN-05-1119  1
2005 Saxena C, Wang H, Kavakli IH, Sancar A, Zhong D. Ultrafast dynamics of resonance energy transfer in cryptochrome. Journal of the American Chemical Society. 127: 7984-5. PMID 15926801 DOI: 10.1021/ja0421607  1
2005 Partch CL, Sancar A. Cryptochromes and circadian photoreception in animals. Methods in Enzymology. 393: 726-45. PMID 15817321 DOI: 10.1016/S0076-6879(05)93038-3  1
2005 Unsal-Kaçmaz K, Mullen TE, Kaufmann WK, Sancar A. Coupling of human circadian and cell cycles by the timeless protein. Molecular and Cellular Biology. 25: 3109-16. PMID 15798197 DOI: 10.1128/MCB.25.8.3109-3116.2005  1
2005 Partch CL, Clarkson MW, Ozgür S, Lee AL, Sancar A. Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor. Biochemistry. 44: 3795-805. PMID 15751956 DOI: 10.1021/bi047545g  1
2005 Hutsell SQ, Sancar A. Nucleotide excision repair, oxidative damage, DNA sequence polymorphisms, and cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1355-7. PMID 15746031 DOI: 10.1158/1078-0432.CCR-05-0024  1
2005 Van Gelder RN, Sancar A. Animal Cryptochromes Handbook of Photosensory Receptors. 259-276. DOI: 10.1002/352760510X.ch12  1
2004 Sancar A. Photolyase and cryptochrome blue-light photoreceptors. Advances in Protein Chemistry. 69: 73-100. PMID 15588840 DOI: 10.1016/S0065-3233(04)69003-6  1
2004 Sancar A, Reardon JT. Nucleotide excision repair in E. coli and man. Advances in Protein Chemistry. 69: 43-71. PMID 15588839 DOI: 10.1016/S0065-3233(04)69002-4  1
2004 Kavakli IH, Sancar A. Analysis of the role of intraprotein electron transfer in photoreactivation by DNA photolyase in vivo. Biochemistry. 43: 15103-10. PMID 15568802 DOI: 10.1021/bi0478796  1
2004 Wang W, Brandt P, Rossi ML, Lindsey-Boltz L, Podust V, Fanning E, Sancar A, Bambara RA. The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1. Proceedings of the National Academy of Sciences of the United States of America. 101: 16762-7. PMID 15556996 DOI: 10.1073/pnas.0407686101  1
2004 Thompson CL, Selby CP, Van Gelder RN, Blaner WS, Lee J, Quadro L, Lai K, Gottesman ME, Sancar A. Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice. Journal of Biological Rhythms. 19: 504-17. PMID 15523112 DOI: 10.1177/0748730404270519  1
2004 Lindsey-Boltz LA, Wauson EM, Graves LM, Sancar A. The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD. Nucleic Acids Research. 32: 4524-30. PMID 15326225 DOI: 10.1093/nar/gkh789  1
2004 Sar F, Lindsey-Boltz LA, Subramanian D, Croteau DL, Hutsell SQ, Griffith JD, Sancar A. Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. The Journal of Biological Chemistry. 279: 39289-95. PMID 15226314 DOI: 10.1074/jbc.M405793200  1
2004 Sancar A, Lindsey-Boltz LA, Unsal-Kaçmaz K, Linn S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annual Review of Biochemistry. 73: 39-85. PMID 15189136 DOI: 10.1146/annurev.biochem.73.011303.073723  1
2004 Sancar A. Regulation of the mammalian circadian clock by cryptochrome. The Journal of Biological Chemistry. 279: 34079-82. PMID 15123698 DOI: 10.1074/jbc.R400016200  1
2004 Thompson CL, Selby CP, Partch CL, Plante DT, Thresher RJ, Araujo F, Sancar A. Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction. Brain Research. Molecular Brain Research. 122: 158-66. PMID 15010208 DOI: 10.1016/j.molbrainres.2003.12.006  1
2004 Unsal-Kaçmaz K, Sancar A. Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities. Molecular and Cellular Biology. 24: 1292-300. PMID 14729973 DOI: 10.1128/MCB.24.3.1292-1300.2003  1
2004 Reardon JT, Sancar A. Thermodynamic cooperativity and kinetic proofreading in DNA damage recognition and repair. Cell Cycle (Georgetown, Tex.). 3: 141-4. PMID 14712076  1
2004 Saxena C, Sancar A, Zhong D. Femtosecond dynamics of DNA photolyase: Energy transfer of antenna initiation and electron transfer of cofactor reduction Journal of Physical Chemistry B. 108: 18026-18033. DOI: 10.1021/jp048376c  1
2003 Van Gelder RN, Sancar A. Cryptochromes and inner retinal non-visual irradiance detection. Novartis Foundation Symposium. 253: 31-42; discussion 42. PMID 14712913  1
2003 Selby CP, Sancar A. Characterization of transcription-repair coupling factors in E. coli and humans. Methods in Enzymology. 371: 300-24. PMID 14712710 DOI: 10.1016/S0076-6879(03)71023-4  1
2003 Reardon JT, Sancar A. Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease. Genes & Development. 17: 2539-51. PMID 14522951 DOI: 10.1101/gad.1131003  1
2003 Thompson CL, Bowes Rickman C, Shaw SJ, Ebright JN, Kelly U, Sancar A, Rickman DW. Expression of the blue-light receptor cryptochrome in the human retina. Investigative Ophthalmology & Visual Science. 44: 4515-21. PMID 14507900 DOI: 10.1167/iovs.03-0303  1
2003 Worthington EN, Kavakli IH, Berrocal-Tito G, Bondo BE, Sancar A. Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from Vibrio cholerae. The Journal of Biological Chemistry. 278: 39143-54. PMID 12878596 DOI: 10.1074/jbc.M305792200  1
2003 Sancar A. Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors. Chemical Reviews. 103: 2203-37. PMID 12797829 DOI: 10.1021/cr0204348  1
2003 Wang D, Hara R, Singh G, Sancar A, Lippard SJ. Nucleotide excision repair from site-specifically platinum-modified nucleosomes. Biochemistry. 42: 6747-53. PMID 12779329 DOI: 10.1021/bi034264k  1
2003 Hara R, Sancar A. Effect of damage type on stimulation of human excision nuclease by SWI/SNF chromatin remodeling factor. Molecular and Cellular Biology. 23: 4121-5. PMID 12773556 DOI: 10.1128/MCB.23.12.4121-4125.2003  1
2003 Oğrünç M, Sancar A. Identification and characterization of human MUS81-MMS4 structure-specific endonuclease. The Journal of Biological Chemistry. 278: 21715-20. PMID 12686547 DOI: 10.1074/jbc.M302484200  1
2003 Ozgur S, Sancar A. Purification and properties of human blue-light photoreceptor cryptochrome 2. Biochemistry. 42: 2926-32. PMID 12627958 DOI: 10.1021/bi026963n  1
2003 Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A. Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proceedings of the National Academy of Sciences of the United States of America. 100: 1633-8. PMID 12578958 DOI: 10.1073/pnas.0437927100  1
2002 Kavakli IH, Sancar A. Circadian photoreception in humans and mice. Molecular Interventions. 2: 484-92. PMID 14993400 DOI: 10.1124/mi.2.8.484  1
2002 Van Gelder RN, Gibler TM, Tu D, Embry K, Selby CP, Thompson CL, Sancar A. Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms. Journal of Neurogenetics. 16: 181-203. PMID 12696673 DOI: 10.1080/01677060215306  1
2002 Wisor JP, O'Hara BF, Terao A, Selby CP, Kilduff TS, Sancar A, Edgar DM, Franken P. A role for cryptochromes in sleep regulation. Bmc Neuroscience. 3: 20. PMID 12495442 DOI: 10.1186/1471-2202-3-20  1
2002 Thompson CL, Sancar A. Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock. Oncogene. 21: 9043-56. PMID 12483519 DOI: 10.1038/sj.onc.1205958  1
2002 Hara R, Sancar A. The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle. Molecular and Cellular Biology. 22: 6779-87. PMID 12215535 DOI: 10.1128/MCB.22.19.6779-6787.2002  1
2002 Reardon JT, Sancar A. Molecular anatomy of the human excision nuclease assembled at sites of DNA damage. Molecular and Cellular Biology. 22: 5938-45. PMID 12138203 DOI: 10.1128/MCB.22.16.5938-5945.2002  1
2002 Cermakian N, Pando MP, Thompson CL, Pinchak AB, Selby CP, Gutierrez L, Wells DE, Cahill GM, Sancar A, Sassone-Corsi P. Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases. Current Biology : Cb. 12: 844-8. PMID 12015122 DOI: 10.1016/S0960-9822(02)00835-7  1
2002 Unsal-Kaçmaz K, Makhov AM, Griffith JD, Sancar A. Preferential binding of ATR protein to UV-damaged DNA. Proceedings of the National Academy of Sciences of the United States of America. 99: 6673-8. PMID 12011431 DOI: 10.1073/pnas.102167799  1
2002 Griffith JD, Lindsey-Boltz LA, Sancar A. Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy. The Journal of Biological Chemistry. 277: 15233-6. PMID 11907025 DOI: 10.1074/jbc.C200129200  1
2002 Wakasugi M, Kawashima A, Morioka H, Linn S, Sancar A, Mori T, Nikaido O, Matsunaga T. DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. The Journal of Biological Chemistry. 277: 1637-40. PMID 11705987 DOI: 10.1074/jbc.C100610200  1
2001 George JW, Salazar EP, Vreeswijk MP, Lamerdin JE, Reardon JT, Zdzienicka MZ, Sancar A, Kadkhodayan S, Tebbs RS, Mullenders LH, Thompson LH. Restoration of nucleotide excision repair in a helicase-deficient XPD mutant from intragenic suppression by a trichothiodystrophy mutation. Molecular and Cellular Biology. 21: 7355-65. PMID 11585917 DOI: 10.1128/MCB.21.21.7355-7365.2001  1
2001 Lindsey-Boltz LA, Bermudez VP, Hurwitz J, Sancar A. Purification and characterization of human DNA damage checkpoint Rad complexes Proceedings of the National Academy of Sciences of the United States of America. 98: 11236-11241. PMID 11572977 DOI: 10.1073/pnas.201373498  1
2001 Thompson CL, Blaner WS, Van Gelder RN, Lai K, Quadro L, Colantuoni V, Gottesman ME, Sancar A. Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 11708-13. PMID 11562477 DOI: 10.1073/pnas.201301498  1
2001 Branum ME, Reardon JT, Sancar A. DNA repair excision nuclease attacks undamaged DNA: A potential source of spontaneous mutations Journal of Biological Chemistry. 276: 25421-25426. PMID 11353769 DOI: 10.1074/jbc.M101032200  1
2000 Sancar A, Thompson C, Thresher RJ, Araujo F, Mo J, Ozgur S, Vagas E, Dawut L, Selby CP. Photolyase/cryptochrome family blue-light photoreceptors use light energy to repair DNA or set the circadian clock. Cold Spring Harbor Symposia On Quantitative Biology. 65: 157-71. PMID 12760030  1
2000 Selby CP, Thompson C, Schmitz TM, Van Gelder RN, Sancar A. Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 14697-702. PMID 11114194 DOI: 10.1073/pnas.260498597  1
2000 Hara R, Mo J, Sancar A. DNA damage in the nucleosome core is refractory to repair by human excision nuclease Molecular and Cellular Biology. 20: 9173-9181. PMID 11094069 DOI: 10.1128/MCB.20.24.9173-9181.2000  1
2000 Sancar A. Cryptochrome: The second photoactive pigment in the eye and its role in circadian photoreception Annual Review of Biochemistry. 69: 31-67. PMID 10966452 DOI: 10.1146/annurev.biochem.69.1.31  1
2000 Shibutani S, Reardon JT, Suzuki N, Sancar A. Excision of tamoxifen-DNA adducts by the human nucleotide excision repair system. Cancer Research. 60: 2607-10. PMID 10825130  1
2000 Mu D, Bessho T, Nechev LV, Chen DJ, Harris TM, Hearst JE, Sancar A. DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts. Molecular and Cellular Biology. 20: 2446-54. PMID 10713168 DOI: 10.1128/MCB.20.7.2446-2454.2000  1
2000 Bessho T, Sancar A. Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease Journal of Biological Chemistry. 275: 7451-7454. PMID 10713044 DOI: 10.1074/jbc.275.11.7451  1
1999 Kay CW, Feicht R, Schulz K, Sadewater P, Sancar A, Bacher A, Möbius K, Richter G, Weber S. EPR, ENDOR, and TRIPLE resonance spectroscopy on the neutral flavin radical in Escherichia coli DNA photolyase. Biochemistry. 38: 16740-8. PMID 10606505 DOI: 10.1021/bi991442u  1
1999 Miyamoto Y, Sancar A. Circadian regulation of cryptochrome genes in the mouse Molecular Brain Research. 71: 238-243. PMID 10521578 DOI: 10.1016/S0169-328X(99)00192-8  1
1999 Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, Takahashi JS, Sancar A. Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proceedings of the National Academy of Sciences of the United States of America. 96: 12114-9. PMID 10518585 DOI: 10.1073/pnas.96.21.12114  1
1999 Reardon JT, Vaisman A, Chaney SG, Sancar A. Efficient nucleotide excision repair of cisplatin, oxaliplatin, and bis- acetoammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts Cancer Research. 59: 3968-3971. PMID 10463593  1
1999 Hara R, Selby CP, Liu M, Price DH, Sancar A. Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimer Journal of Biological Chemistry. 274: 24779-24786. PMID 10455150 DOI: 10.1074/jbc.274.35.24779  1
1999 Wakasugi M, Sancar A. Order of assembly of human DNA repair excision nuclease Journal of Biological Chemistry. 274: 18759-18768. PMID 10373492 DOI: 10.1074/jbc.274.26.18759  1
1999 Petit C, Sancar A. Nucleotide excision repair: From E. coli to man Biochimie. 81: 15-25. PMID 10214906 DOI: 10.1016/S0300-9084(99)80034-0  1
1999 Gindt YM, Vollenbroek E, Westphal K, Sackett H, Sancar A, Babcock GT. Origin of the transient electron paramagnetic resonance signals in DNA photolyase. Biochemistry. 38: 3857-66. PMID 10194296 DOI: 10.1021/bi981191+  1
1999 Sancar A. Excision repair invades the territory of mismatch repair Nature Genetics. 21: 247-249. PMID 10080168 DOI: 10.1038/6753  1
1999 Selby CP, Sancar A. A third member of the photolyase/blue-light photoreceptor family in Drosophila: A putative circadian photoreceptor Photochemistry and Photobiology. 69: 105-107. PMID 10063805  1
1999 Petit C, Sancar A. From DNA photolyases to photoreceptors regulating biological clocks | La vie en bleu: Des ADN photolyases aux photorecepteurs reglant les horloges biologiques Medecine/Sciences. 15: 1411-1418.  1
1998 Thresher RJ, Vitaterna MH, Miyamoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L, Smithies O, Takahashi JS, Sancar A. Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science (New York, N.Y.). 282: 1490-4. PMID 9822380  1
1998 Khan SG, Levy HL, Legerski R, Quackenbush E, Reardon JT, Emmert S, Sancar A, Li L, Schneider TD, Cleaver JE, Kraemer KH. Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia. The Journal of Investigative Dermatology. 111: 791-6. PMID 9804340 DOI: 10.1046/j.1523-1747.1998.00391.x  1
1998 Ogrünç M, Becker DF, Ragsdale SW, Sancar A. Nucleotide excision repair in the third kingdom. Journal of Bacteriology. 180: 5796-8. PMID 9791138  1
1998 Wakasugi M, Sancar A. Assembly, subunit composition, and footprint of human DNA repair excision nuclease Proceedings of the National Academy of Sciences of the United States of America. 95: 6669-6674. PMID 9618470 DOI: 10.1073/pnas.95.12.6669  1
1998 Miyamoto Y, Sancar A. Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals Proceedings of the National Academy of Sciences of the United States of America. 95: 6097-6102. PMID 9600923 DOI: 10.1073/pnas.95.11.6097  1
1998 Kazantsev A, Bullock SK, Sancar A, Cordeiro-Stone M. Generation and characterization of an immortal cell line of xeroderma pigmentosum group E Mutation Research - Dna Repair. 407: 55-65. PMID 9539981 DOI: 10.1016/S0921-8777(97)00059-1  1
1997 Zhao X, Liu J, Hsu DS, Zhao S, Taylor JS, Sancar A. Reaction mechanism of (6-4) photolyase Journal of Biological Chemistry. 272: 32580-32590. PMID 9405473 DOI: 10.1074/jbc.272.51.32580  1
1997 Zhao S, Sancar A. Human Blue-light Photoreceptor hCRY2 Specifically Interacts with Protein Serine/Threonine Phosphatase 5 and Modulates Its Activity Photochemistry and Photobiology. 66: 727-731. PMID 9383998  1
1997 Bessho T, Mu D, Sancar A. Initiation of DNA interstrand cross-link repair in humans: The nucleotide excision repair system makes dual incisions 5' to the cross- linked base and removes a 22- to 28-nucleotide-long damage-free strand Molecular and Cellular Biology. 17: 6822-6830. PMID 9372913  1
1997 Mu D, Wakasugi M, Hsu DS, Sancar A. Characterization of reaction intermediates of human excision repair nuclease Journal of Biological Chemistry. 272: 28971-28979. PMID 9360969 DOI: 10.1074/jbc.272.46.28971  1
1997 Selby CP, Sancar A. Cockayne syndrome group B protein enhances elongation by RNA polymerase II Proceedings of the National Academy of Sciences of the United States of America. 94: 11205-11209. PMID 9326587 DOI: 10.1073/pnas.94.21.11205  1
1997 Reardon JT, Bessho T, Kung HC, Bolton PH, Sancar A. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients Proceedings of the National Academy of Sciences of the United States of America. 94: 9463-9468. PMID 9256505 DOI: 10.1073/pnas.94.17.9463  1
1997 Wakasugi M, Reardon JT, Sancar A. The Non-catalytic function of XPG protein during dual incision in human nucleotide excision repair Journal of Biological Chemistry. 272: 16030-16034. PMID 9188507 DOI: 10.1074/jbc.272.25.16030  1
1997 Mu D, Sancar A. DNA excision repair assays Progress in Nucleic Acid Research and Molecular Biology. 56: 63-81. PMID 9187051  1
1997 Perelman B, Dafni N, Naiman T, Eli D, Yaakov M, Yang Feng TL, Sinha S, Weber G, Khodaei S, Sancar A, Dotan I, Canaani D. Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus Genomics. 41: 397-405. PMID 9169138 DOI: 10.1006/geno.1997.4623  1
1997 Mu D, Sancar A. Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans Journal of Biological Chemistry. 272: 7570-7573. PMID 9065408 DOI: 10.1074/jbc.272.12.7570  1
1997 Selby CP, Drapkin R, Reinberg D, Sancar A. RNA polymerase II stalled at a thymine dimer: Footprint and effect on excision repair Nucleic Acids Research. 25: 787-793. PMID 9016630 DOI: 10.1093/nar/25.4.787  1
1997 Bessho T, Sancar A, Thompson LH, Thelen MP. Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex Journal of Biological Chemistry. 272: 3833-3837. PMID 9013642 DOI: 10.1074/jbc.272.6.3833  1
1997 Mu D, Tursun M, Duckett DR, Drummond JT, Modrich P, Sancar A. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Molecular and Cellular Biology. 17: 760-9. PMID 9001230  1
1997 Selby CP, Sancar A. Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II Journal of Biological Chemistry. 272: 1885-1890. PMID 8999876 DOI: 10.1074/jbc.272.3.1885  1
1997 Langenbacher T, Zhao X, Bieser G, Heelis PF, Sancar A, Michel-Beyerle ME. Substrate and temperature dependence of DNA photolyase repair activity examined with ultrafast spectroscopy Journal of the American Chemical Society. 119: 10532-10536. DOI: 10.1021/ja9721024  1
1997 McCutchen-Maloney SL, Hwang M, Bessho T, Sancar A, Thelen MP. Characterization of the XPF endonuclease complex Faseb Journal. 11: A1371.  1
1996 Hsu DS, Zhao X, Zhao S, Kazantsev A, Wang RP, Todo T, Wei YF, Sancar A. Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins. Biochemistry. 35: 13871-7. PMID 8909283 DOI: 10.1021/bi962209o  1
1996 Brookman KW, Lamerdin JE, Thelen MP, Hwang M, Reardon JT, Sancar A, Zhou ZQ, Walter CA, Parris CN, Thompson LH. ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs Molecular and Cellular Biology. 16: 6553-6562. PMID 8887684  1
1996 Chaney SG, Sancar A. DNA repair: Enzymatic mechanisms and relevance to drug response Journal of the National Cancer Institute. 88: 1346-1360. PMID 8827012  1
1996 Zamble DB, Mu D, Reardon JT, Sancar A, Lippard SJ. Repair of cisplatin-DNA adducts by the mammalian excision nuclease Biochemistry. 35: 10004-10013. PMID 8756462 DOI: 10.1021/bi960453+  1
1996 Reardon JT, Mu D, Sancar A. Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease Journal of Biological Chemistry. 271: 19451-19456. PMID 8702634 DOI: 10.1074/jbc.271.32.19451  1
1996 Reardon JT, Ge H, Gibbs E, Sancar A, Hurwitz J, Pan ZQ. Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH. Proceedings of the National Academy of Sciences of the United States of America. 93: 6482-7. PMID 8692841 DOI: 10.1073/pnas.93.13.6482  1
1996 Duckett DR, Drummond JT, Murchie AIH, Reardon JT, Sancar A, Lilley DMJ, Modrich P. Humnan MutSα recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct Proceedings of the National Academy of Sciences of the United States of America. 93: 6443-6447. PMID 8692834  1
1996 Kim ST, Malhotra K, Ryo H, Sancar A, Todo T. Purification and characterization of Drosophila melanogaster photolyase Mutation Research - Dna Repair. 363: 97-104. PMID 8676930 DOI: 10.1016/0921-8777(96)00003-1  1
1996 Kazantsev A, Mu D, Nichols AF, Zhao X, Linn S, Sancar A. Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system. Proceedings of the National Academy of Sciences of the United States of America. 93: 5014-8. PMID 8643521 DOI: 10.1073/pnas.93.10.5014  1
1996 Matsunaga T, Park CH, Bessho T, Mu D, Sancar A. Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease Journal of Biological Chemistry. 271: 11047-11050. PMID 8626644 DOI: 10.1074/jbc.271.19.11047  1
1996 Mu D, Hsu DS, Sancar A. Reaction mechanism of human DNA repair excision nuclease Journal of Biological Chemistry. 271: 8285-8294. PMID 8626523 DOI: 10.1074/jbc.271.14.8285  1
1996 Sancar A. No "End of history" for photolyases Science. 272: 48-49. PMID 8600535  1
1996 Reardon JT, Thompson LH, Sancar A. Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6-10 Have Normal General Excision Repair Activity Nucleic Acids Research. 25: 1015-1021. DOI: 10.1093/nar/25.5.1015  1
1996 Sancar A. Molecular mechanism of excision repair in humans Faseb Journal. 10: A959.  1
1987 Sancar GB, Jorns MS, Payne G, Fluke DJ, Rupert CS, Sancar A. Action mechanism of Escherichia coli DNA photolyase. III. Photolysis of the enzyme-substrate complex and the absolute action spectrum. The Journal of Biological Chemistry. 262: 492-8. PMID 3539941  1
1984 Sancar GB, Smith FW, Lorence MC, Rupert CS, Sancar A. Sequences of the Escherichia coli photolyase gene and protein. The Journal of Biological Chemistry. 259: 6033-8. PMID 6325460  1
1979 Sancar A, Rupert CS. Penicillin selection of Escherichia coli deoxyribonucleic acid repair mutants. Journal of Bacteriology. 138: 779-82. PMID 378937  1
1978 Sancar A, Rupert CS. Cloning of the phr gene and amplification of photolyase in Escherichia coli. Gene. 4: 295-308. PMID 369954 DOI: 10.1016/0378-1119(78)90047-1  1
1978 Sancar A, Rupert CS. Determination of plasmid molecular weights from ultraviolet sensitivities. Nature. 272: 471-2. PMID 345128 DOI: 10.1038/272471a0  1
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