| Year |
Citation |
Score |
| 2024 |
Shen Y, Dinh HV, Cruz ER, Chen Z, Bartman CR, Xiao T, Call CM, Ryseck RP, Pratas J, Weilandt D, Baron H, Subramanian A, Fatma Z, Wu ZY, Dwaraknath S, ... ... Rabinowitz JD, et al. Mitochondrial ATP generation is more proteome efficient than glycolysis. Nature Chemical Biology. PMID 38448734 DOI: 10.1038/s41589-024-01571-y |
0.536 |
|
| 2024 |
Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, ... ... Rabinowitz JD, et al. Reprogramming neuroblastoma by diet-enhanced polyamine depletion. Biorxiv : the Preprint Server For Biology. PMID 38260457 DOI: 10.1101/2024.01.07.573662 |
0.517 |
|
| 2024 |
McBride MJ, Hunter CJ, Zhang Z, TeSlaa T, Xu X, Ducker GS, Rabinowitz JD. Glycine homeostasis requires reverse SHMT flux. Cell Metabolism. 36: 103-115.e4. PMID 38171330 DOI: 10.1016/j.cmet.2023.12.001 |
0.705 |
|
| 2023 |
Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, ... ... Rabinowitz J, et al. Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. Basic Research in Cardiology. 118: 47. PMID 37930434 DOI: 10.1007/s00395-023-01017-x |
0.532 |
|
| 2023 |
Bartman CR, Faubert B, Rabinowitz JD, DeBerardinis RJ. Metabolic pathway analysis using stable isotopes in patients with cancer. Nature Reviews. Cancer. 23: 863-878. PMID 37907620 DOI: 10.1038/s41568-023-00632-z |
0.304 |
|
| 2023 |
Leitner BP, Lee WD, Zhu W, Zhang X, Gaspar RC, Li Z, Rabinowitz JD, Perry RJ. Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis. Plos One. 18: e0286525. PMID 37410734 DOI: 10.1371/journal.pone.0286525 |
0.308 |
|
| 2023 |
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, ... ... Rabinowitz JD, et al. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. PMID 36725930 DOI: 10.1038/s41586-022-05661-6 |
0.514 |
|
| 2023 |
Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, ... ... Rabinowitz JD, et al. Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy. Molecular Cancer Therapeutics. OF1. PMID 36602953 DOI: 10.1158/1535-7163.MCT-22-0766 |
0.689 |
|
| 2022 |
Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, ... ... Rabinowitz JD, et al. NAD precursors cycle between host tissues and the gut microbiome. Cell Metabolism. 34: 1947-1959.e5. PMID 36476934 DOI: 10.1016/j.cmet.2022.11.004 |
0.73 |
|
| 2022 |
Zhao H, Teng D, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca di Magliano M, Boland GM, Flaherty KT, ... ... Rabinowitz JD, et al. Myeloid-derived itaconate suppresses cytotoxic CD8 T cells and promotes tumour growth. Nature Metabolism. PMID 36376563 DOI: 10.1038/s42255-022-00676-9 |
0.453 |
|
| 2022 |
Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, ... ... Rabinowitz JD, et al. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metabolism. 34: 1410. PMID 36070684 DOI: 10.1016/j.cmet.2022.08.006 |
0.722 |
|
| 2022 |
Zeng X, Xing X, Gupta M, Keber FC, Lopez JG, Lee YJ, Roichman A, Wang L, Neinast MD, Donia MS, Wühr M, Jang C, Rabinowitz JD. Gut bacterial nutrient preferences quantified in vivo. Cell. 185: 3441-3456.e19. PMID 36055202 DOI: 10.1016/j.cell.2022.07.020 |
0.73 |
|
| 2022 |
Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, ... ... Rabinowitz JD, et al. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med (New York, N.Y.). 3: 119-136. PMID 35425930 DOI: 10.1016/j.medj.2021.12.008 |
0.769 |
|
| 2022 |
Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Spatially resolved isotope tracing reveals tissue metabolic activity. Nature Methods. 19: 223-230. PMID 35132243 DOI: 10.1038/s41592-021-01378-y |
0.792 |
|
| 2022 |
Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG, Lee WD, Zeng X, Jang C, Rabinowitz JD. Circulating metabolite homeostasis achieved through mass action. Nature Metabolism. PMID 35058631 DOI: 10.1038/s42255-021-00517-1 |
0.761 |
|
| 2021 |
Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz GJ, Clasquin MF, Rabinowitz JD. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nature Metabolism. PMID 34845393 DOI: 10.1038/s42255-021-00487-4 |
0.782 |
|
| 2021 |
Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD. Methionine synthase supports tumour tetrahydrofolate pools. Nature Metabolism. 3: 1512-1520. PMID 34799699 DOI: 10.1038/s42255-021-00465-w |
0.516 |
|
| 2021 |
Chen L, Lu W, Wang L, Xing X, Chen Z, Teng X, Zeng X, Muscarella AD, Shen Y, Cowan A, McReynolds MR, Kennedy BJ, Lato AM, Campagna SR, Singh M, ... Rabinowitz JD, et al. Metabolite discovery through global annotation of untargeted metabolomics data. Nature Methods. PMID 34711973 DOI: 10.1038/s41592-021-01303-3 |
0.727 |
|
| 2021 |
Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Systems. PMID 34706266 DOI: 10.1016/j.cels.2021.09.014 |
0.473 |
|
| 2021 |
Parkhitko AA, Wang L, Filine E, Jouandin P, Leshchiner D, Binari R, Asara JM, Rabinowitz JD, Perrimon N. A genetic model of methionine restriction extends health- and lifespan. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34588310 DOI: 10.1073/pnas.2110387118 |
0.303 |
|
| 2021 |
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, ... ... Rabinowitz JD, et al. Metabolic decisions in development and disease-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34414571 DOI: 10.1111/nyas.14678 |
0.337 |
|
| 2021 |
Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar MD, Gil Z, Diamond DJ, Rabinowitz JD, Rosen S, Melstrom LG. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. International Journal of Biological Sciences. 17: 2240-2251. PMID 34239352 DOI: 10.7150/ijbs.60473 |
0.459 |
|
| 2021 |
Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar MD, Gil Z, Diamond DJ, Rabinowitz JD, Rosen S, Melstrom LG. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. International Journal of Biological Sciences. 17: 2240-2251. PMID 34239352 DOI: 10.7150/ijbs.60473 |
0.459 |
|
| 2020 |
Green R, Sonal, Wang L, Hart SFM, Lu W, Skelding D, Burton JC, Mi H, Capel A, Chen HA, Lin A, Subramaniam AR, Rabinowitz JD, Shou W. Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect. Plos Biology. 18: e3000757. PMID 32833957 DOI: 10.1371/Journal.Pbio.3000757 |
0.377 |
|
| 2020 |
Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD. Quantitative Fluxomics of Circulating Metabolites. Cell Metabolism. PMID 32791100 DOI: 10.1016/J.Cmet.2020.07.013 |
0.811 |
|
| 2020 |
Ghassemi S, Martinez-Becerra FJ, Master AM, Richman SA, Heo D, Leferovich J, Tu Y, García-Cañaveras JC, Ayari A, Lu Y, Wang A, Rabinowitz JD, Milone MC, June CH, O'Connor RS. Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design. Molecular Therapy. Methods & Clinical Development. 18: 595-606. PMID 32775494 DOI: 10.1016/J.Omtm.2020.07.008 |
0.319 |
|
| 2020 |
Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science (New York, N.Y.). PMID 32732282 DOI: 10.1126/Science.Aba8984 |
0.346 |
|
| 2020 |
Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD. The small intestine shields the liver from fructose-induced steatosis. Nature Metabolism. 2: 586-593. PMID 32694791 DOI: 10.1038/s42255-020-0222-9 |
0.737 |
|
| 2020 |
Ghergurovich JM, Esposito M, Chen Z, Wang JZ, Bhatt V, Lan T, White E, Kang Y, Guo JY, Rabinowitz JD. Glucose-6-phosphate dehydrogenase is not essential for K-Ras-driven tumor growth or metastasis. Cancer Research. PMID 32661137 DOI: 10.1158/0008-5472.Can-19-2486 |
0.302 |
|
| 2020 |
Lu W, Xing X, Wang L, Chen L, Zhang S, McReynolds MR, Rabinowitz JD. Improved annotation of untargeted metabolomics data through buffer modifications that shift adduct mass and intensity. Analytical Chemistry. PMID 32614575 DOI: 10.1021/Acs.Analchem.0C00985 |
0.323 |
|
| 2020 |
Gibney PA, Chen A, Schieler A, Chen JC, Xu Y, Hendrickson DG, McIsaac RS, Rabinowitz JD, Botstein D. A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1. Plos One. 15: e0233779. PMID 32470059 DOI: 10.1371/Journal.Pone.0233779 |
0.396 |
|
| 2020 |
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, ... Rabinowitz JD, et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nature Chemical Biology. PMID 32393898 DOI: 10.1038/S41589-020-0533-X |
0.379 |
|
| 2020 |
García-Cañaveras JC, Lancho O, Ducker GS, Ghergurovich JM, Xu X, da Silva-Diz V, Minuzzo S, Indraccolo S, Kim H, Herranz D, Rabinowitz JD. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. PMID 32382081 DOI: 10.1038/S41375-020-0845-6 |
0.708 |
|
| 2020 |
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, ... Rabinowitz JD, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 579: 586-591. PMID 32214246 DOI: 10.1038/S41586-020-2101-7 |
0.768 |
|
| 2020 |
Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, ... ... Rabinowitz JD, et al. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metabolism. PMID 32187526 DOI: 10.1016/J.Cmet.2020.02.017 |
0.574 |
|
| 2020 |
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR. PMID 31941752 DOI: 10.1158/1541-7786.Mcr-19-0606 |
0.716 |
|
| 2020 |
DeBerardinis R, Rabinowitz JD. Decision letter: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma Elife. DOI: 10.7554/Elife.56782.Sa1 |
0.334 |
|
| 2020 |
Ghergurovich JM, O’Shaughnessy J, Levin MK, Killian A, Hendricks W, Espina V, Rabinowitz JD. Abstract P3-02-06: Tracing glucose catabolism in human triple negative breast cancer tumors Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-02-06 |
0.386 |
|
| 2020 |
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713. DOI: 10.1158/1538-7445.Am2020-5713 |
0.725 |
|
| 2020 |
Ghassemi S, Martinez-Becerra F, Master A, Richman S, Heo D, Leferovich J, Tu Y, Garcia-Canaveras J, Ayari A, Lu Y, Wang A, Rabinowitz J, Milone M, O'Connor R. Novel media formulations to enhance Chimeric Antigen Receptor (CAR) T-cell potency and anti-tumor cell function for adoptive immunotherapy Cytotherapy. 22: S133. DOI: 10.1016/J.Jcyt.2020.03.260 |
0.302 |
|
| 2019 |
Chen L, Zhang Z, Hoshino A, Zheng HD, Morley M, Arany Z, Rabinowitz JD. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. Nature Metabolism. 1: 404-415. PMID 32694724 DOI: 10.1038/s42255-019-0043-x |
0.343 |
|
| 2019 |
Gokhale S, Lu W, Zhu S, Liu Y, Hart RP, Rabinowitz JD, Xie P. Elevated Choline Kinase α-Mediated Choline Metabolism Supports the Prolonged Survival of TRAF3-Deficient B Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 31826940 DOI: 10.4049/Jimmunol.1900658 |
0.365 |
|
| 2019 |
Dinh HV, Suthers PF, Chan SHJ, Shen Y, Xiao T, Deewan A, Jagtap SS, Zhao H, Rao CV, Rabinowitz JD, Maranas CD. A comprehensive genome-scale model for IFO0880 accounting for functional genomics and phenotypic data. Metabolic Engineering Communications. 9: e00101. PMID 31720216 DOI: 10.1016/J.Mec.2019.E00101 |
0.368 |
|
| 2019 |
Stine RR, Sakers AP, TeSlaa T, Kissig M, Stine ZE, Kwon CW, Cheng L, Lim HW, Kaestner KH, Rabinowitz JD, Seale P. PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell. PMID 31564549 DOI: 10.1016/J.Stem.2019.08.017 |
0.389 |
|
| 2019 |
Park JO, Tanner LB, Wei MH, Khana DB, Jacobson TB, Zhang Z, Rubin SA, Li SH, Higgins MB, Stevenson DM, Amador-Noguez D, Rabinowitz JD. Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nature Chemical Biology. PMID 31548693 DOI: 10.1038/S41589-019-0364-9 |
0.39 |
|
| 2019 |
Ron-Harel N, Ghergurovich JM, Notarangelo G, LaFleur MW, Tsubosaka Y, Sharpe AH, Rabinowitz JD, Haigis MC. T Cell Activation Depends on Extracellular Alanine. Cell Reports. 28: 3011-3021.e4. PMID 31533027 DOI: 10.1016/J.Celrep.2019.08.034 |
0.363 |
|
| 2019 |
Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ, Rabinowitz J, Craft J, Flavell RA. Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function. Nature. PMID 31447485 DOI: 10.1038/S41586-019-1490-Y |
0.333 |
|
| 2019 |
Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, ... ... Rabinowitz JD, et al. Novel pyrrolo[3,2-d]pyrimidine compounds target mitochondrial and cytosolic one-carbon metabolism with broad-spectrum antitumor efficacy. Molecular Cancer Therapeutics. PMID 31289137 DOI: 10.1158/1535-7163.Mct-19-0037 |
0.741 |
|
| 2019 |
Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, ... ... Rabinowitz JD, et al. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metabolism. PMID 31257152 DOI: 10.1016/J.Cmet.2019.06.002 |
0.757 |
|
| 2019 |
Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ, Rabinowitz J, Craft J, Flavell RA. Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function. Nature. PMID 31217581 DOI: 10.1038/S41586-019-1311-3 |
0.351 |
|
| 2019 |
Schober AF, Mathis AD, Ingle C, Park JO, Chen L, Rabinowitz JD, Junier I, Rivoire O, Reynolds KA. A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism. Cell Reports. 27: 3359-3370.e7. PMID 31189117 DOI: 10.1016/J.Celrep.2019.05.030 |
0.406 |
|
| 2019 |
García-Cañaveras JC, Chen L, Rabinowitz JD. The Tumor Metabolic Microenvironment: Lessons from Lactate. Cancer Research. PMID 31171526 DOI: 10.1158/0008-5472.Can-18-3726 |
0.324 |
|
| 2019 |
Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metabolism. PMID 31155495 DOI: 10.1016/J.Cmet.2019.05.005 |
0.336 |
|
| 2019 |
Estrella MA, Du J, Chen L, Rath S, Prangley E, Chitrakar A, Aoki T, Schedl P, Rabinowitz J, Korennykh A. The metabolites NADP and NADPH are the targets of the circadian protein Nocturnin (Curled). Nature Communications. 10: 2367. PMID 31147539 DOI: 10.1038/S41467-019-10125-Z |
0.423 |
|
| 2019 |
Chen L, Zhang Z, Hoshino A, Zheng HD, Morley M, Arany Z, Rabinowitz JD. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. Nature Metabolism. 1: 404-415. PMID 31058257 |
0.342 |
|
| 2019 |
Bradley PH, Gibney PA, Botstein D, Troyanskaya OG, Rabinowitz JD. Minor Isozymes Tailor Yeast Metabolism to Carbon Availability. Msystems. 4. PMID 30834327 DOI: 10.1128/mSystems.00170-18 |
0.803 |
|
| 2019 |
Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metabolism. PMID 30773464 DOI: 10.1016/J.Cmet.2019.01.014 |
0.696 |
|
| 2019 |
Dekhne A, Shah K, Ducker GS, Nayeen MJ, Katinas JM, Wong J, Doshi A, Bao X, Kalpage H, Liu J, Kim S, Wallace-Povirk A, Ning C, O'Connor C, Hou Z, ... ... Rabinowitz JD, et al. Abstract 2992: Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2-d]pyrimidine antifolates Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2992 |
0.719 |
|
| 2018 |
Wang L, Xing X, Chen L, Yang L, Su X, Rabitz HA, Lu W, Rabinowitz JD. Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics. Analytical Chemistry. PMID 30586294 DOI: 10.1021/Acs.Analchem.8B03132 |
0.54 |
|
| 2018 |
Ron-Harel N, Notarangelo G, Ghergurovich JM, Paulo JA, Sage PT, Santos D, Satterstrom FK, Gygi SP, Rabinowitz JD, Sharpe AH, Haigis MC. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proceedings of the National Academy of Sciences of the United States of America. 115: 13347-13352. PMID 30530686 DOI: 10.1073/Pnas.1804149115 |
0.369 |
|
| 2018 |
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, ... Rabinowitz JD, et al. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nature Immunology. PMID 30478397 DOI: 10.1038/S41590-018-0255-3 |
0.317 |
|
| 2018 |
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, ... Rabinowitz JD, et al. Autophagy maintains tumour growth through circulating arginine. Nature. PMID 30429607 DOI: 10.1038/S41586-018-0697-7 |
0.393 |
|
| 2018 |
Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA. Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell. PMID 30057115 DOI: 10.1016/J.Cell.2018.06.031 |
0.377 |
|
| 2018 |
Li SH, Li Z, Park JO, King CG, Rabinowitz JD, Wingreen NS, Gitai Z. Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. Nature Microbiology. PMID 30038306 DOI: 10.1038/S41564-018-0199-2 |
0.344 |
|
| 2018 |
Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT. 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Molecular Genetics and Metabolism. PMID 30031689 DOI: 10.1016/J.Ymgme.2018.06.006 |
0.728 |
|
| 2018 |
Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD. Four Key Steps Control Glycolytic Flux in Mammalian Cells. Cell Systems. PMID 29960885 DOI: 10.1016/J.Cels.2018.06.003 |
0.358 |
|
| 2018 |
Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA. Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife. 7. PMID 29893687 DOI: 10.7554/Elife.33246 |
0.315 |
|
| 2018 |
Jang C, Chen L, Rabinowitz JD. Metabolomics and Isotope Tracing. Cell. 173: 822-837. PMID 29727671 DOI: 10.1016/J.Cell.2018.03.055 |
0.384 |
|
| 2018 |
Liu L, Su X, Quinn WJ, Hui S, Krukenberg K, Frederick DW, Redpath P, Zhan L, Chellappa K, White E, Migaud M, Mitchison TJ, Baur JA, Rabinowitz JD. Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Cell Metabolism. PMID 29685734 DOI: 10.1016/J.Cmet.2018.03.018 |
0.429 |
|
| 2018 |
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nature Medicine. PMID 29578539 DOI: 10.1038/Nm.4514 |
0.345 |
|
| 2018 |
Lanaspa MA, Andres-Hernando A, Orlicky DJ, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe MF, Rabinowitz JD, Johnson RJ, Tolan DR. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice. The Journal of Clinical Investigation. PMID 29533924 DOI: 10.1172/Jci94427 |
0.372 |
|
| 2018 |
Gibney PA, Schieler A, Chen JC, Bacha-Hummel JM, Botstein M, Volpe M, Silverman SJ, Xu Y, Bennett BD, Rabinowitz JD, Botstein D. Common and Divergent Features of Galactose-1-phosphate and Fructose-1-phosphate Toxicity in Yeast. Molecular Biology of the Cell. PMID 29444955 DOI: 10.1091/Mbc.E17-11-0666 |
0.646 |
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| 2018 |
McKee SE, Zhang S, Chen L, Rabinowitz JD, Reyes TM. Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. Journal of Neurochemistry. PMID 29423909 DOI: 10.1111/Jnc.14319 |
0.322 |
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| 2018 |
Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metabolism. 27: 351-361.e3. PMID 29414685 DOI: 10.1016/J.Cmet.2017.12.016 |
0.362 |
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| 2018 |
Morscher RJ, Ducker GS, Li SH, Mayer JA, Gitai Z, Sperl W, Rabinowitz JD. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. PMID 29364879 DOI: 10.1038/Nature25460 |
0.714 |
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| 2018 |
Pavlova NN, Hui S, Ghergurovich JM, Fan J, Intlekofer AM, White RM, Rabinowitz JD, Thompson CB, Zhang J. As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid. Cell Metabolism. PMID 29337136 DOI: 10.1016/J.Cmet.2017.12.006 |
0.355 |
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| 2018 |
Dekhne AS, Ducker GS, Frühauf J, Shah K, Nayeen MJ, Wallace-Povirk A, O'Connor C, Hou Z, Polin L, Gangjee A, Rabinowitz JD, Matherly LH. Abstract 3980: Dual targeting mitochondrial and cytosolic one-carbon metabolism via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2-d]pyrimidine antifolates Cancer Research. 78: 3980-3980. DOI: 10.1158/1538-7445.Am2018-3980 |
0.73 |
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| 2017 |
Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, ... ... Rabinowitz JD, et al. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. PMID 29153836 DOI: 10.1016/J.Cell.2017.10.037 |
0.352 |
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| 2017 |
Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 114: 11404-11409. PMID 29073064 DOI: 10.1073/Pnas.1706617114 |
0.729 |
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| 2017 |
Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD. Glucose feeds the TCA cycle via circulating lactate. Nature. PMID 29045397 DOI: 10.1038/Nature24057 |
0.376 |
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| 2017 |
Kim HI, Raffler J, Lu W, Lee JJ, Abbey D, Saleheen D, Rabinowitz JD, Bennett MJ, Hand NJ, Brown C, Rader DJ. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. American Journal of Human Genetics. PMID 28942964 DOI: 10.1016/J.Ajhg.2017.08.008 |
0.317 |
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| 2017 |
Liu L, Rowe GC, Yang S, Li J, Damilano F, Chan MC, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann BK, Rabinowitz J, Das S, Rosenzweig A, et al. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circulation Research. PMID 28928113 DOI: 10.1161/Circresaha.117.311456 |
0.323 |
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| 2017 |
Nofal M, Zhang K, Han S, Rabinowitz JD. mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein. Molecular Cell. PMID 28918901 DOI: 10.1016/J.Molcel.2017.08.011 |
0.306 |
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| 2017 |
Zhang Z, Chen L, Liu L, Su X, Rabinowitz JD. Chemical basis for deuterium labeling of fat and NADPH. Journal of the American Chemical Society. PMID 28911221 DOI: 10.1021/Jacs.7B08012 |
0.362 |
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| 2017 |
Rebecca VW, Nicastri MC, McLaughlin N, Fennelly C, McAfee Q, Ronghe A, Nofal M, Lim CY, Witze E, Chude CI, Zhang G, Alicea GM, Piao S, Murugan S, Ojha R, ... ... Rabinowitz J, et al. A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery. PMID 28899863 DOI: 10.1158/2159-8290.Cd-17-0741 |
0.324 |
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| 2017 |
Zhang Y, Kurupati R, Liu L, Zhou XY, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis GC, Schuchter LM, Xu W, Amaravadi R, Xiao M, Sadek N, ... ... Rabinowitz JD, et al. Enhancing CD8(+) T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 32: 377-391.e9. PMID 28898698 DOI: 10.1016/J.Ccell.2017.08.004 |
0.329 |
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| 2017 |
Oslund RC, Su X, Haugbro M, Kee JM, Esposito M, David Y, Wang B, Ge E, Perlman DH, Kang Y, Muir TW, Rabinowitz JD. Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate. Nature Chemical Biology. PMID 28805803 DOI: 10.1038/Nchembio.2453 |
0.374 |
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| 2017 |
Chen L, Ducker GS, Lu W, Teng X, Rabinowitz JD. An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate. Analytical and Bioanalytical Chemistry. PMID 28799108 DOI: 10.1007/S00216-017-0514-4 |
0.701 |
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| 2017 |
Lu W, Su X, Klein MS, Lewis IA, Fiehn O, Rabinowitz JD. Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annual Review of Biochemistry. 86: 277-304. PMID 28654323 DOI: 10.1146/Annurev-Biochem-061516-044952 |
0.349 |
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| 2017 |
Rajeshkumar NV, Yabuuchi S, Pai S, De Oliveira E, Kamphorst JJ, Rabinowitz JD, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang CV. Treatment of pancreatic cancer patient-derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28611197 DOI: 10.1158/1078-0432.Ccr-17-1115 |
0.313 |
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| 2017 |
Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang CC, Qian J, Lie N, Lanzillotta C, Rabinowitz JD, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Molecular and Cellular Endocrinology. PMID 28554803 DOI: 10.1016/J.Mce.2017.05.024 |
0.316 |
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| 2017 |
Choi J, Rajagopal A, Xu YF, Rabinowitz JD, O'Shea EK. A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae. Plos One. 12: e0176085. PMID 28520786 DOI: 10.1371/Journal.Pone.0176085 |
0.333 |
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| 2017 |
Lu W, Wang L, Chen L, Hui S, Rabinowitz JD. Extraction and quantitation of NAD(P)(H). Antioxidants & Redox Signaling. PMID 28497978 DOI: 10.1089/Ars.2017.7014 |
0.328 |
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| 2017 |
Su X, Lu W, Rabinowitz JD. Metabolite Spectral Accuracy on Orbitraps. Analytical Chemistry. PMID 28471646 DOI: 10.1021/Acs.Analchem.7B00396 |
0.306 |
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| 2016 |
Davidson SM, Jonas O, Keibler MA, Hou HW, Luengo A, Mayers JR, Wyckoff J, Del Rosario AM, Whitman M, Chin CR, Condon KJ, Lammers A, Kellersberger KA, Stall BK, Stephanopoulos G, ... ... Rabinowitz JD, et al. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nature Medicine. PMID 28024083 DOI: 10.1038/Nm.4256 |
0.336 |
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| 2016 |
Papazyan R, Sun Z, Kim YH, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metabolism. PMID 27866836 DOI: 10.1016/J.Cmet.2016.10.012 |
0.323 |
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| 2016 |
Hackett SR, Zanotelli VR, Xu W, Goya J, Park JO, Perlman DH, Gibney PA, Botstein D, Storey JD, Rabinowitz JD. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science (New York, N.Y.). 354. PMID 27789812 DOI: 10.1126/Science.Aaf2786 |
0.428 |
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| 2016 |
Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, Kang Y, Rabinowitz JD. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. 24: 640-641. PMID 27732838 DOI: 10.1016/J.Cmet.2016.09.011 |
0.702 |
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| 2016 |
Ducker GS, Rabinowitz JD. One-Carbon Metabolism in Health and Disease. Cell Metabolism. PMID 27641100 DOI: 10.1016/J.Cmet.2016.08.009 |
0.75 |
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| 2016 |
Moloughney JG, Kim PK, Vega-Cotto NM, Wu CC, Zhang S, Adlam M, Lynch T, Chou PC, Rabinowitz JD, Werlen G, Jacinto E. mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. Molecular Cell. PMID 27570073 DOI: 10.1016/J.Molcel.2016.07.015 |
0.438 |
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| 2016 |
Guo JY, Teng X, Laddha SV, Ma S, Van Nostrand SC, Yang Y, Khor S, Chan CS, Rabinowitz JD, White E. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes & Development. PMID 27516533 DOI: 10.1101/Gad.283416.116 |
0.373 |
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| 2016 |
Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, Dephoure N, Satterstrom FK, Sheffer M, Spinelli JB, Gygi S, Rabinowitz JD, Sharpe AH, Haigis MC. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metabolism. 24: 104-17. PMID 27411012 DOI: 10.1016/J.Cmet.2016.06.007 |
0.392 |
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| 2016 |
Teng X, Emmett MJ, Lazar MA, Goldberg E, Rabinowitz JD. Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis. Acs Chemical Biology. PMID 27333189 DOI: 10.1021/Acschembio.6B00290 |
0.323 |
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| 2016 |
Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, Kang Y, Rabinowitz JD. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. PMID 27211901 DOI: 10.1016/J.Cmet.2016.04.016 |
0.724 |
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| 2016 |
Park JO, Rubin SA, Xu YF, Amador-Noguez D, Fan J, Shlomi T, Rabinowitz JD. Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. Nature Chemical Biology. PMID 27159581 DOI: 10.1038/Nchembio.2077 |
0.38 |
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| 2016 |
Bren A, Park JO, Towbin BD, Dekel E, Rabinowitz JD, Alon U. Glucose becomes one of the worst carbon sources for E.coli on poor nitrogen sources due to suboptimal levels of cAMP. Scientific Reports. 6: 24834. PMID 27109914 DOI: 10.1038/Srep24834 |
0.337 |
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| 2016 |
Liu L, Shah S, Fan J, Park JO, Wellen KE, Rabinowitz JD. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nature Chemical Biology. PMID 26999781 DOI: 10.1038/Nchembio.2047 |
0.43 |
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| 2016 |
Zong WX, Rabinowitz JD, White E. Mitochondria and Cancer. Molecular Cell. 61: 667-76. PMID 26942671 DOI: 10.1016/J.Molcel.2016.02.011 |
0.336 |
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| 2016 |
Ducker GS, Esposito MB, Kang Y, Rabinowitz JD. Abstract A14: Role of mitochondrial folate metabolism in cancer cell growth and proliferation Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A14 |
0.757 |
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| 2016 |
Suri V, Mainolfi N, Friedman A, Moyer MP, Ducker G, Rabinowitz JD, Manfredi M. Abstract 232: Pharmacological and genetic dissection of one carbon pathway provides novel insights into generation, transformation and utilization of one carbon units Cancer Research. 76: 232-232. DOI: 10.1158/1538-7445.Am2016-232 |
0.406 |
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| 2016 |
Jacinto E, Moloughney J, Kim PK, Vega-Cotto NM, Wu C, Lynch T, Zhang S, Adlam M, Guntaka S, Chou P, Rabinowitz JD, Werlen G. Abstract 21: The mTORC2 target Akt is regulated in response to glutamine metabolite levels Cancer Research. 76: 21-21. DOI: 10.1158/1538-7445.Am2016-21 |
0.452 |
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| 2016 |
Liu L, Chen L, Ducker G, Park J, Shah S, Wellen KE, Rabinowitz JD. Abstract 1013: Quantification of NADPH balance in cancer Cancer Research. 76: 1013-1013. DOI: 10.1158/1538-7445.Am2016-1013 |
0.385 |
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| 2015 |
Su X, Wellen KE, Rabinowitz JD. Metabolic control of methylation and acetylation. Current Opinion in Chemical Biology. 30: 52-60. PMID 26629854 DOI: 10.1016/J.Cbpa.2015.10.030 |
0.385 |
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| 2015 |
Bott AJ, Peng IC, Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, et al. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metabolism. PMID 26603296 DOI: 10.1016/J.Cmet.2015.09.025 |
0.34 |
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| 2015 |
Mok WW, Park JO, Rabinowitz JD, Brynildsen MP. RNA Futile Cycling in Model Persisters Derived from MazF Accumulation. Mbio. 6. PMID 26578677 DOI: 10.1128/Mbio.01588-15 |
0.399 |
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| 2015 |
Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Matrinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ, Maitra A. Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function. Cancer Research. PMID 26113084 DOI: 10.1158/0008-5472.Can-15-0108 |
0.358 |
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| 2015 |
Gibney PA, Schieler A, Chen JC, Rabinowitz JD, Botstein D. Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter. Proceedings of the National Academy of Sciences of the United States of America. 112: 6116-21. PMID 25918382 DOI: 10.1073/Pnas.1506289112 |
0.396 |
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| 2015 |
Purdy JG, Shenk T, Rabinowitz JD. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Reports. 10: 1375-85. PMID 25732827 DOI: 10.1016/J.Celrep.2015.02.003 |
0.346 |
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| 2015 |
Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, ... ... Rabinowitz JD, et al. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Current Opinion in Biotechnology. 34: 189-201. PMID 25731751 DOI: 10.1016/J.Copbio.2015.02.003 |
0.368 |
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| 2015 |
Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, Thompson CB, Rabinowitz JD. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Research. 75: 544-53. PMID 25644265 DOI: 10.1158/0008-5472.Can-14-2211 |
0.359 |
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| 2015 |
Ducker GS, Rabinowitz JD. ZMP: a master regulator of one-carbon metabolism. Molecular Cell. 57: 203-4. PMID 25616065 DOI: 10.1016/J.Molcel.2015.01.012 |
0.718 |
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| 2015 |
Xu YF, Lu W, Rabinowitz JD. Avoiding misannotation of in-source fragmentation products as cellular metabolites in liquid chromatography-mass spectrometry-based metabolomics. Analytical Chemistry. 87: 2273-81. PMID 25591916 DOI: 10.1021/Ac504118Y |
0.338 |
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| 2015 |
Aristilde L, Lewis IA, Park JO, Rabinowitz JD. Hierarchy in pentose sugar metabolism in Clostridium acetobutylicum. Applied and Environmental Microbiology. 81: 1452-62. PMID 25527534 DOI: 10.1128/Aem.03199-14 |
0.457 |
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| 2015 |
Ducker GS, Chen L, Teng X, Rabinowitz JD. Abstract 4709: Compartmental flexibility in mammalian folate metabolism Cancer Research. 75: 4709-4709. DOI: 10.1158/1538-7445.Am2015-4709 |
0.738 |
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| 2015 |
Jacinto E, Moloughney J, Lynch T, Wu C, Ibironke O, Navia A, Chou P, Zhang S, Rabinowitz J, Werlen G. Abstract 1150: mTORC2 enhances flux through the hexosamine biosynthetic pathway by regulation of GFAT1 expression Cancer Research. 75: 1150-1150. DOI: 10.1158/1538-7445.Am2015-1150 |
0.438 |
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| 2014 |
Kamphorst JJ, Chung MK, Fan J, Rabinowitz JD. Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate. Cancer & Metabolism. 2: 23. PMID 25671109 DOI: 10.1186/2049-3002-2-23 |
0.387 |
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| 2014 |
Hwang J, Purdy JG, Wu K, Rabinowitz JD, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 111: E5706-15. PMID 25512541 DOI: 10.1073/Pnas.1422361112 |
0.317 |
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| 2014 |
Castellana M, Wilson MZ, Xu Y, Joshi P, Cristea IM, Rabinowitz JD, Gitai Z, Wingreen NS. Enzyme clustering accelerates processing of intermediates through metabolic channeling. Nature Biotechnology. 32: 1011-8. PMID 25262299 DOI: 10.1038/Nbt.3018 |
0.382 |
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| 2014 |
Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, Olin-Sandoval V, Grüning N, Krüger A, Tauqeer Alam M, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M. The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Biological Reviews of the Cambridge Philosophical Society. PMID 25243985 DOI: 10.1111/Brv.12140 |
0.452 |
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| 2014 |
Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/J.Molcel.2014.08.018 |
0.347 |
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| 2014 |
Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.Cd-14-0250 |
0.354 |
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| 2014 |
Mathew R, Khor S, Hackett SR, Rabinowitz JD, Perlman DH, White E. Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity. Molecular Cell. 55: 916-30. PMID 25175026 DOI: 10.1016/J.Molcel.2014.07.019 |
0.363 |
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| 2014 |
Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, White E. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discovery. 4: 914-27. PMID 24875857 DOI: 10.1158/2159-8290.Cd-14-0363 |
0.315 |
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| 2014 |
Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Quantitative flux analysis reveals folate-dependent NADPH production. Nature. 510: 298-302. PMID 24805240 DOI: 10.1038/Nature13236 |
0.435 |
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| 2014 |
Breunig JS, Hackett SR, Rabinowitz JD, Kruglyak L. Genetic basis of metabolome variation in yeast. Plos Genetics. 10: e1004142. PMID 24603560 DOI: 10.1371/Journal.Pgen.1004142 |
0.453 |
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| 2014 |
Shlomi T, Fan J, Tang B, Kruger WD, Rabinowitz JD. Quantitation of cellular metabolic fluxes of methionine. Analytical Chemistry. 86: 1583-91. PMID 24397525 DOI: 10.1021/Ac4032093 |
0.464 |
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| 2014 |
Fan J, Teng X, Liu L, Looper R, Rabinowitz J. Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate and promotes histone methylation Cancer & Metabolism. 2: P75. DOI: 10.1186/2049-3002-2-S1-P75 |
0.305 |
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| 2014 |
Park J, Rubin S, Xu Y, Amador-Noguez D, Fan J, Rabinowitz J. Comprehensive quantitation of metabolite concentrations, gross reaction fluxes, and reaction free energies across cells from four organisms Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P54 |
0.327 |
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| 2014 |
Lu W, Zhang S, Teng X, Melamud E, Lazar MA, White E, Rabinowitz JD. LC-MS and GC-MS based metabolomics platform for cancer research Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P41 |
0.346 |
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| 2014 |
Liu L, Shah S, Fan J, Wellen K, Rabinowitz J. Quantification of NADPH balance during adipogenesis Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P40 |
0.362 |
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| 2014 |
Altman BJ, Hsieh A, Gouw AM, Stine ZE, Venkataraman A, Bellovin DI, Diskin SJ, Lu W, Zhang S, Felsher DW, Maris JM, Lazar MA, Rabinowitz JD, Hogenesch JB, Dang CV. Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism Cancer Research. 74: 2953-2953. DOI: 10.1158/1538-7445.Am2014-2953 |
0.384 |
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| 2014 |
Wu C, Lynch T, Moloughney J, Navia A, Ibironke O, Chou P, Vega-Cotto NM, Zhang S, Rabinowitz J, Werlen G, Jacinto E. Abstract 2441: mTOR complex 2 modulates glycosylation of CD147 via the hexosamine biosynthetic pathway Cancer Research. 74: 2441-2441. DOI: 10.1158/1538-7445.Am2014-2441 |
0.371 |
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| 2013 |
Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Reports. 5: 1725-36. PMID 24360963 DOI: 10.1016/J.Celrep.2013.11.040 |
0.581 |
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| 2013 |
Fan J, Kamphorst JJ, Mathew R, Chung MK, White E, Shlomi T, Rabinowitz JD. Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Molecular Systems Biology. 9: 712. PMID 24301801 DOI: 10.1038/Msb.2013.65 |
0.403 |
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| 2013 |
Grady SL, Purdy JG, Rabinowitz JD, Shenk T. Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 110: E5006-15. PMID 24297925 DOI: 10.1073/Pnas.1321305110 |
0.385 |
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| 2013 |
Tepper N, Noor E, Amador-Noguez D, Haraldsdóttir HS, Milo R, Rabinowitz J, Liebermeister W, Shlomi T. Steady-State Metabolite Concentrations Reflect a Balance between Maximizing Enzyme Efficiency and Minimizing Total Metabolite Load Plos One. 8. PMID 24086517 DOI: 10.1371/Journal.Pone.0075370 |
0.383 |
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| 2013 |
Fan J, Kamphorst JJ, Rabinowitz JD, Shlomi T. Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux. The Journal of Biological Chemistry. 288: 31363-9. PMID 24030823 DOI: 10.1074/Jbc.M113.502740 |
0.415 |
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| 2013 |
Rabinowitz JD, Silhavy TJ. Systems biology: metabolite turns master regulator. Nature. 500: 283-4. PMID 23925111 DOI: 10.1038/Nature12544 |
0.305 |
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| 2013 |
Reaves ML, Young BD, Hosios AM, Xu YF, Rabinowitz JD. Pyrimidine homeostasis is accomplished by directed overflow metabolism. Nature. 500: 237-41. PMID 23903661 DOI: 10.1038/Nature12445 |
0.819 |
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| 2013 |
Guo JY, Karsli-Uzunbas G, Mathew R, Aisner SC, Kamphorst JJ, Strohecker AM, Chen G, Price S, Lu W, Teng X, Snyder E, Santanam U, Dipaola RS, Jacks T, Rabinowitz JD, et al. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes & Development. 27: 1447-61. PMID 23824538 DOI: 10.1101/Gad.219642.113 |
0.314 |
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| 2013 |
Koyuncu E, Purdy JG, Rabinowitz JD, Shenk T. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. Plos Pathogens. 9: e1003333. PMID 23696731 DOI: 10.1371/Journal.Ppat.1003333 |
0.369 |
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| 2013 |
Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/Pnas.1307237110 |
0.367 |
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| 2013 |
Xu YF, Létisse F, Absalan F, Lu W, Kuznetsova E, Brown G, Caudy AA, Yakunin AF, Broach JR, Rabinowitz JD. Nucleotide degradation and ribose salvage in yeast. Molecular Systems Biology. 9: 665. PMID 23670538 DOI: 10.1038/Msb.2013.21 |
0.391 |
|
| 2013 |
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/Nature12138 |
0.332 |
|
| 2013 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 497: 652. PMID 23615611 DOI: 10.1038/Nature12164 |
0.311 |
|
| 2013 |
Shlomi T, Rabinowitz JD. Metabolism: Cancer mistunes methylation. Nature Chemical Biology. 9: 293-4. PMID 23594782 DOI: 10.1038/Nchembio.1234 |
0.341 |
|
| 2012 |
Xu YF, Zhao X, Glass DS, Absalan F, Perlman DH, Broach JR, Rabinowitz JD. Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation. Molecular Cell. 48: 52-62. PMID 22902555 DOI: 10.1016/J.Molcel.2012.07.013 |
0.319 |
|
| 2012 |
Reaves ML, Sinha S, Rabinowitz JD, Kruglyak L, Redfield RJ. Absence of detectable arsenate in DNA from arsenate-grown GFAJ-1 cells. Science (New York, N.Y.). 337: 470-3. PMID 22773140 DOI: 10.1126/Science.1219861 |
0.769 |
|
| 2012 |
Grady SL, Hwang J, Vastag L, Rabinowitz JD, Shenk T. Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase. Journal of Virology. 86: 8259-68. PMID 22623791 DOI: 10.1128/Jvi.00495-12 |
0.79 |
|
| 2012 |
Rabinowitz JD, Vastag L. Teaching the design principles of metabolism. Nature Chemical Biology. 8: 497-501. PMID 22596190 DOI: 10.1038/Nchembio.969 |
0.791 |
|
| 2012 |
Xu YF, Amador-Noguez D, Reaves ML, Feng XJ, Rabinowitz JD. Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase. Nature Chemical Biology. 8: 562-8. PMID 22522319 DOI: 10.1038/Nchembio.941 |
0.794 |
|
| 2012 |
Ye J, Mancuso A, Tong X, Ward PS, Fan J, Rabinowitz JD, Thompson CB. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6904-9. PMID 22509023 DOI: 10.1073/Pnas.1204176109 |
0.361 |
|
| 2012 |
Peterson CN, Levchenko I, Rabinowitz JD, Baker TA, Silhavy TJ. RpoS proteolysis is controlled directly by ATP levels in Escherichia coli. Genes & Development. 26: 548-53. PMID 22426532 DOI: 10.1101/Gad.183517.111 |
0.415 |
|
| 2012 |
Clasquin MF, Melamud E, Rabinowitz JD. LC-MS data processing with MAVEN: a metabolomic analysis and visualization engine. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit14.11. PMID 22389014 DOI: 10.1002/0471250953.Bi1411S37 |
0.74 |
|
| 2012 |
Terry LJ, Vastag L, Rabinowitz JD, Shenk T. Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 3071-6. PMID 22315427 DOI: 10.1073/Pnas.1200494109 |
0.802 |
|
| 2012 |
Kamphorst JJ, Cross JR, Fan J, Lu W, White E, Thompson CB, Rabinowitz JD. Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P25 |
0.355 |
|
| 2012 |
Rajeshkumar NV, Dutta P, Kamphorst J, Le A, Yabuuchi S, Wilde RFd, Campbell NR, Oliveira ED, Jesus-Acosta AD, Rabinowitz J, Laheru D, Jain SK, Hidalgo M, Thompson CB, Hoff DDV, et al. Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-61 |
0.363 |
|
| 2011 |
Rabinowitz JD, Purdy JG, Vastag L, Shenk T, Koyuncu E. Metabolomics in drug target discovery. Cold Spring Harbor Symposia On Quantitative Biology. 76: 235-46. PMID 22114327 DOI: 10.1101/Sqb.2011.76.010694 |
0.803 |
|
| 2011 |
Kamphorst JJ, Fan J, Lu W, White E, Rabinowitz JD. Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism. Analytical Chemistry. 83: 9114-22. PMID 22004349 DOI: 10.1021/Ac202220B |
0.367 |
|
| 2011 |
Doucette CD, Schwab DJ, Wingreen NS, Rabinowitz JD. α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition. Nature Chemical Biology. 7: 894-901. PMID 22002719 DOI: 10.1038/Nchembio.685 |
0.689 |
|
| 2011 |
Amador-Noguez D, Brasg IA, Feng XJ, Roquet N, Rabinowitz JD. Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum. Applied and Environmental Microbiology. 77: 7984-97. PMID 21948824 DOI: 10.1128/Aem.05374-11 |
0.423 |
|
| 2011 |
Strelko CL, Lu W, Dufort FJ, Seyfried TN, Chiles TC, Rabinowitz JD, Roberts MF. Itaconic acid is a mammalian metabolite induced during macrophage activation. Journal of the American Chemical Society. 133: 16386-9. PMID 21919507 DOI: 10.1021/Ja2070889 |
0.36 |
|
| 2011 |
Vastag L, Koyuncu E, Grady SL, Shenk TE, Rabinowitz JD. Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. Plos Pathogens. 7: e1002124. PMID 21779165 DOI: 10.1371/Journal.Ppat.1002124 |
0.81 |
|
| 2011 |
Petti AA, Crutchfield CA, Rabinowitz JD, Botstein D. Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 108: E1089-98. PMID 21734149 DOI: 10.1073/Pnas.1101494108 |
0.731 |
|
| 2011 |
Clasquin MF, Melamud E, Singer A, Gooding JR, Xu X, Dong A, Cui H, Campagna SR, Savchenko A, Yakunin AF, Rabinowitz JD, Caudy AA. Riboneogenesis in yeast. Cell. 145: 969-80. PMID 21663798 DOI: 10.1016/J.Cell.2011.05.022 |
0.783 |
|
| 2011 |
Reaves ML, Rabinowitz JD. Characteristic phenotypes associated with ptsN-null mutants in Escherichia coli K-12 are absent in strains with functional ilvG. Journal of Bacteriology. 193: 4576-81. PMID 21531803 DOI: 10.1128/Jb.00325-11 |
0.781 |
|
| 2011 |
Vastag L, Jorgensen P, Peshkin L, Wei R, Rabinowitz JD, Kirschner MW. Remodeling of the metabolome during early frog development. Plos One. 6: e16881. PMID 21347444 DOI: 10.1371/Journal.Pone.0016881 |
0.802 |
|
| 2011 |
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes & Development. 25: 460-70. PMID 21317241 DOI: 10.1101/Gad.2016311 |
0.356 |
|
| 2011 |
Klosinska MM, Crutchfield CA, Bradley PH, Rabinowitz JD, Broach JR. Yeast cells can access distinct quiescent states. Genes & Development. 25: 336-49. PMID 21289062 DOI: 10.1101/Gad.2011311 |
0.798 |
|
| 2011 |
Hart Y, Madar D, Yuan J, Bren A, Mayo AE, Rabinowitz JD, Alon U. Robust control of nitrogen assimilation by a bifunctional enzyme in E. coli. Molecular Cell. 41: 117-27. PMID 21211727 DOI: 10.1016/J.Molcel.2010.12.023 |
0.344 |
|
| 2011 |
Reaves ML, Rabinowitz JD. Metabolomics in systems microbiology. Current Opinion in Biotechnology. 22: 17-25. PMID 21050741 DOI: 10.1016/J.Copbio.2010.10.001 |
0.815 |
|
| 2011 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Erratum: Branched tricarboxylic acid metabolism in Plasmodium falciparum Nature. 469: 432-432. DOI: 10.1038/Nature09712 |
0.385 |
|
| 2010 |
Rabinowitz JD, White E. Autophagy and metabolism. Science (New York, N.Y.). 330: 1344-8. PMID 21127245 DOI: 10.1126/Science.1193497 |
0.397 |
|
| 2010 |
Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes & Development. 24: 2784-99. PMID 21106670 DOI: 10.1101/Gad.1985910 |
0.39 |
|
| 2010 |
Melamud E, Vastag L, Rabinowitz JD. Metabolomic analysis and visualization engine for LC-MS data. Analytical Chemistry. 82: 9818-26. PMID 21049934 DOI: 10.1021/Ac1021166 |
0.784 |
|
| 2010 |
Lemons JM, Feng XJ, Bennett BD, Legesse-Miller A, Johnson EL, Raitman I, Pollina EA, Rabitz HA, Rabinowitz JD, Coller HA. Quiescent fibroblasts exhibit high metabolic activity. Plos Biology. 8: e1000514. PMID 21049082 DOI: 10.1371/Journal.Pbio.1000514 |
0.711 |
|
| 2010 |
Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Research. 70: 8981-7. PMID 21045145 DOI: 10.1158/0008-5472.Can-10-1666 |
0.642 |
|
| 2010 |
Merritt JH, Ha DG, Cowles KN, Lu W, Morales DK, Rabinowitz J, Gitai Z, O'Toole GA. Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases. Mbio. 1. PMID 20978535 DOI: 10.1128/Mbio.00183-10 |
0.326 |
|
| 2010 |
Crutchfield CA, Lu W, Melamud E, Rabinowitz JD. Mass spectrometry-based metabolomics of yeast. Methods in Enzymology. 470: 393-426. PMID 20946819 DOI: 10.1016/S0076-6879(10)70016-1 |
0.717 |
|
| 2010 |
Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, Christofk HR, Wagner G, Rabinowitz JD, Asara JM, Cantley LC. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science (New York, N.Y.). 329: 1492-9. PMID 20847263 DOI: 10.1126/Science.1188015 |
0.423 |
|
| 2010 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 466: 774-8. PMID 20686576 DOI: 10.1038/Nature09301 |
0.429 |
|
| 2010 |
Amador-Noguez D, Feng XJ, Fan J, Roquet N, Rabitz H, Rabinowitz JD. Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum. Journal of Bacteriology. 192: 4452-61. PMID 20622067 DOI: 10.1128/Jb.00490-10 |
0.455 |
|
| 2010 |
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... Rabinowitz JD, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 465: 966. PMID 20559394 DOI: 10.1038/nature09132 |
0.528 |
|
| 2010 |
Kwon YK, Higgins MB, Rabinowitz JD. Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli. Acs Chemical Biology. 5: 787-95. PMID 20553049 DOI: 10.1021/Cb100096F |
0.332 |
|
| 2010 |
Goyal S, Yuan J, Chen T, Rabinowitz JD, Wingreen NS. Achieving optimal growth through product feedback inhibition in metabolism. Plos Computational Biology. 6: e1000802. PMID 20532205 DOI: 10.1371/Journal.Pcbi.1000802 |
0.424 |
|
| 2010 |
Goodarzi H, Bennett BD, Amini S, Reaves ML, Hottes AK, Rabinowitz JD, Tavazoie S. Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Molecular Systems Biology. 6: 378. PMID 20531407 DOI: 10.1038/Msb.2010.33 |
0.772 |
|
| 2010 |
Lu W, Clasquin MF, Melamud E, Amador-Noguez D, Caudy AA, Rabinowitz JD. Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Analytical Chemistry. 82: 3212-21. PMID 20349993 DOI: 10.1021/Ac902837X |
0.754 |
|
| 2010 |
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 17: 225-34. PMID 20171147 DOI: 10.1016/J.Ccr.2010.01.020 |
0.578 |
|
| 2010 |
Monds RD, Newell PD, Wagner JC, Schwartzman JA, Lu W, Rabinowitz JD, O'Toole GA. Di-adenosine tetraphosphate (Ap4A) metabolism impacts biofilm formation by Pseudomonas fluorescens via modulation of c-di-GMP-dependent pathways. Journal of Bacteriology. 192: 3011-23. PMID 20154123 DOI: 10.1128/Jb.01571-09 |
0.387 |
|
| 2010 |
Lu X, Bennet B, Mu E, Rabinowitz J, Kang Y. Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model Journal of Biological Chemistry. 285: 9317-9321. PMID 20139083 DOI: 10.1074/Jbc.C110.104448 |
0.377 |
|
| 2010 |
Boer VM, Crutchfield CA, Bradley PH, Botstein D, Rabinowitz JD. Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations. Molecular Biology of the Cell. 21: 198-211. PMID 19889834 DOI: 10.1091/Mbc.E09-07-0597 |
0.798 |
|
| 2010 |
Fantin VR, Dang L, White DW, Gross S, Bittinger MA, Driggers EM, Jang HG, Jin S, Keenan MC, Marks KM, Yen KE, Ward PS, Prins RM, Liau LM, Bennett BD, ... Rabinowitz JD, et al. Abstract 33: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate Cancer Research. 70: 33-33. DOI: 10.1158/1538-7445.Am10-33 |
0.606 |
|
| 2009 |
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... Rabinowitz JD, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 462: 739-44. PMID 19935646 DOI: 10.1038/Nature08617 |
0.609 |
|
| 2009 |
Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nature Chemical Biology. 5: 891-5. PMID 19838203 DOI: 10.1038/Nchembio.237 |
0.316 |
|
| 2009 |
Yuan J, Doucette CD, Fowler WU, Feng XJ, Piazza M, Rabitz HA, Wingreen NS, Rabinowitz JD. Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli. Molecular Systems Biology. 5: 302. PMID 19690571 DOI: 10.1038/Msb.2009.60 |
0.688 |
|
| 2009 |
Bennett BD, Kimball EH, Gao M, Osterhout R, Van Dien SJ, Rabinowitz JD. Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nature Chemical Biology. 5: 593-9. PMID 19561621 DOI: 10.1038/Nchembio.186 |
0.675 |
|
| 2009 |
Shinar G, Rabinowitz JD, Alon U. Robustness in glyoxylate bypass regulation. Plos Computational Biology. 5: e1000297. PMID 19266029 DOI: 10.1371/Journal.Pcbi.1000297 |
0.333 |
|
| 2009 |
Bradley PH, Brauer MJ, Rabinowitz JD, Troyanskaya OG. Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae. Plos Computational Biology. 5: e1000270. PMID 19180179 DOI: 10.1371/Journal.Pcbi.1000270 |
0.797 |
|
| 2008 |
Munger J, Bennett BD, Parikh A, Feng XJ, McArdle J, Rabitz HA, Shenk T, Rabinowitz JD. Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy. Nature Biotechnology. 26: 1179-86. PMID 18820684 DOI: 10.1038/Nbt.1500 |
0.693 |
|
| 2008 |
Kwon YK, Lu W, Melamud E, Khanam N, Bognar A, Rabinowitz JD. A domino effect in antifolate drug action in Escherichia coli. Nature Chemical Biology. 4: 602-8. PMID 18724364 DOI: 10.1038/Nchembio.108 |
0.412 |
|
| 2008 |
Yuan J, Bennett BD, Rabinowitz JD. Kinetic flux profiling for quantitation of cellular metabolic fluxes. Nature Protocols. 3: 1328-40. PMID 18714301 DOI: 10.1038/Nprot.2008.131 |
0.688 |
|
| 2008 |
Bennett BD, Yuan J, Kimball EH, Rabinowitz JD. Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach. Nature Protocols. 3: 1299-311. PMID 18714298 DOI: 10.1038/Nprot.2008.107 |
0.653 |
|
| 2008 |
Lu W, Bennett BD, Rabinowitz JD. Analytical strategies for LC-MS-based targeted metabolomics. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 871: 236-42. PMID 18502704 DOI: 10.1016/J.Jchromb.2008.04.031 |
0.616 |
|
| 2008 |
Rabinowitz JD, Hsiao JJ, Gryncel KR, Kantrowitz ER, Feng XJ, Li G, Rabitz H. Dissecting enzyme regulation by multiple allosteric effectors: nucleotide regulation of aspartate transcarbamoylase. Biochemistry. 47: 5881-8. PMID 18454556 DOI: 10.1021/Bi8000566 |
0.32 |
|
| 2007 |
Rabinowitz JD, Kimball E. Acidic acetonitrile for cellular metabolome extraction from Escherichia coli. Analytical Chemistry. 79: 6167-73. PMID 17630720 DOI: 10.1021/Ac070470C |
0.319 |
|
| 2007 |
Yuan J, Rabinowitz JD. Differentiating metabolites formed from de novo synthesis versus macromolecule decomposition. Journal of the American Chemical Society. 129: 9294-5. PMID 17616198 DOI: 10.1021/Ja072997C |
0.413 |
|
| 2007 |
Rabinowitz JD. Cellular metabolomics of Escherchia coli. Expert Review of Proteomics. 4: 187-98. PMID 17425455 DOI: 10.1586/14789450.4.2.187 |
0.409 |
|
| 2007 |
Lu W, Kwon YK, Rabinowitz JD. Isotope ratio-based profiling of microbial folates. Journal of the American Society For Mass Spectrometry. 18: 898-909. PMID 17360194 DOI: 10.1016/J.Jasms.2007.01.017 |
0.371 |
|
| 2006 |
Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD. Dynamics of the cellular metabolome during human cytomegalovirus infection. Plos Pathogens. 2: e132. PMID 17173481 DOI: 10.1371/Journal.Ppat.0020132 |
0.43 |
|
| 2006 |
Brauer MJ, Yuan J, Bennett BD, Lu W, Kimball E, Botstein D, Rabinowitz JD. Conservation of the metabolomic response to starvation across two divergent microbes. Proceedings of the National Academy of Sciences of the United States of America. 103: 19302-7. PMID 17159141 DOI: 10.1073/Pnas.0609508103 |
0.67 |
|
| 2006 |
Hess DC, Lu W, Rabinowitz JD, Botstein D. Ammonium toxicity and potassium limitation in yeast. Plos Biology. 4: e351. PMID 17048990 DOI: 10.1371/Journal.Pbio.0040351 |
0.339 |
|
| 2006 |
Yuan J, Fowler WU, Kimball E, Lu W, Rabinowitz JD. Kinetic flux profiling of nitrogen assimilation in Escherichia coli. Nature Chemical Biology. 2: 529-30. PMID 16936719 DOI: 10.1038/Nchembio816 |
0.382 |
|
| 2006 |
Bajad SU, Lu W, Kimball EH, Yuan J, Peterson C, Rabinowitz JD. Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry. Journal of Chromatography. A. 1125: 76-88. PMID 16759663 DOI: 10.1016/J.Chroma.2006.05.019 |
0.344 |
|
| 2006 |
Lu W, Kimball E, Rabinowitz JD. A high-performance liquid chromatography-tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites. Journal of the American Society For Mass Spectrometry. 17: 37-50. PMID 16352439 DOI: 10.1016/J.Jasms.2005.09.001 |
0.353 |
|
| 2002 |
Hall FC, Rabinowitz JD, Busch R, Visconti KC, Belmares M, Patil NS, Cope AP, Patel S, McConnell HM, Mellins ED, Sonderstrup G. Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes. European Journal of Immunology. 32: 662-70. PMID 11857340 DOI: 10.1002/1521-4141(200203)32:3<662::Aid-Immu662>3.0.Co;2-5 |
0.447 |
|
| 2001 |
Patil NS, Pashine A, Belmares MP, Liu W, Kaneshiro B, Rabinowitz J, McConnell H, Mellins ED. Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles Journal of Immunology. 167: 7157-7168. PMID 11739539 DOI: 10.4049/Jimmunol.167.12.7157 |
0.432 |
|
| 2000 |
Belmares MP, Rabinowitz JD, Liu W, Mellins ED, McConnell HM. pH stability of HLA-DR4 complexes with antigenic peptides. Biochemistry. 39: 14558-66. PMID 11087411 DOI: 10.1021/Bi001544G |
0.447 |
|
| 2000 |
Kasson PM, Rabinowitz JD, Schmitt L, Davis MM, McConnell HM. Kinetics of peptide binding to the class II MHC protein I-Ek. Biochemistry. 39: 1048-58. PMID 10653650 DOI: 10.1021/Bi9921337 |
0.444 |
|
| 1998 |
Rabinowitz JD, Vrljic M, Kasson PM, Liang MN, Busch R, Boniface JJ, Davis MM, McConnell HM. Formation of a highly peptide-receptive state of class II MHC. Immunity. 9: 699-709. PMID 9846491 DOI: 10.1016/S1074-7613(00)80667-6 |
0.726 |
|
| 1998 |
Boniface JJ, Rabinowitz JD, Wülfing C, Hampl J, Reich Z, Altman JD, Kantor RM, Beeson C, McConnell HM, Davis MM. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. Immunity. 9: 459-66. PMID 9806632 DOI: 10.1016/S1074-7613(00)80629-9 |
0.638 |
|
| 1998 |
Lee C, Liang MN, Tate KM, Rabinowitz JD, Beeson C, Jones PP, McConnell HM. Evidence that the autoimmune antigen myelin basic protein (MBP) Ac1-9 binds towards one end of the major histocompatibility complex (MHC) cleft. The Journal of Experimental Medicine. 187: 1505-16. PMID 9565642 DOI: 10.1084/Jem.187.9.1505 |
0.676 |
|
| 1998 |
Rabinowitz JD, Vacchino JF, Beeson C, McConnell HM. Potentiometric measurement of intracellular redox activity Journal of the American Chemical Society. 120: 2464-2473. DOI: 10.1021/Ja973560F |
0.767 |
|
| 1997 |
Rabinowitz JD, Rigler P, Carswell-Crumpton C, Beeson C, McConnell HM. Screening for novel drug effects with a microphysiometer: a potent effect of clofilium unrelated to potassium channel blockade. Life Sciences. 61: PL87-94. PMID 9252253 DOI: 10.1016/S0024-3205(97)00543-2 |
0.669 |
|
| 1997 |
Rabinowitz JD, Tate K, Lee C, Beeson C, McConnell HM. Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex. Proceedings of the National Academy of Sciences of the United States of America. 94: 8702-7. PMID 9238041 DOI: 10.1073/Pnas.94.16.8702 |
0.638 |
|
| 1997 |
Wülfing C, Rabinowitz JD, Beeson C, Sjaastad MD, McConnell HM, Davis MM. Kinetics and extent of T cell activation as measured with the calcium signal. The Journal of Experimental Medicine. 185: 1815-25. PMID 9151707 DOI: 10.1084/Jem.185.10.1815 |
0.643 |
|
| 1996 |
Rabinowitz JD, Beeson C, Wülfing C, Tate K, Allen PM, Davis MM, McConnell HM. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity. 5: 125-35. PMID 8769476 DOI: 10.1016/S1074-7613(00)80489-6 |
0.644 |
|
| 1996 |
Beeson C, Rabinowitz J, Tate K, Gütgemann I, Chien YH, Jones PP, Davis MM, McConnell HM. Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface. The Journal of Experimental Medicine. 184: 777-82. PMID 8760833 DOI: 10.1084/Jem.184.2.777 |
0.646 |
|
| 1996 |
Rabinowitz JD, Beeson C, Lyons DS, Davis MM, McConnell HM. Kinetic discrimination in T-cell activation. Proceedings of the National Academy of Sciences of the United States of America. 93: 1401-5. PMID 8643643 DOI: 10.1073/Pnas.93.4.1401 |
0.642 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2021 |
Sugiura A, Andrejeva G, Voss K, Heintzman DR, Xu X, Madden MZ, Ye X, Beier KL, Chowdhury NU, Wolf MM, Young AC, Greenwood DL, Sewell AE, Shahi SK, Freedman SN, ... ... Rabinowitz JD, et al. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. PMID 34767747 DOI: 10.1016/j.immuni.2021.10.011 |
0.296 |
|
| 2012 |
Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. Plos One. 7: e41831. PMID 22848625 DOI: 10.1371/Journal.Pone.0041831 |
0.296 |
|
| 2018 |
Nofal M, Rabinowitz JD. Ribosomes on the night shift. Science (New York, N.Y.). 360: 710-711. PMID 29773733 DOI: 10.1126/Science.Aat7121 |
0.296 |
|
| 2008 |
Piazza M, Feng XJ, Rabinowitz JD, Rabitz H. Diverse metabolic model parameters generate similar methionine cycle dynamics. Journal of Theoretical Biology. 251: 628-39. PMID 18313076 DOI: 10.1016/J.Jtbi.2007.12.009 |
0.295 |
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| 2017 |
Song Y, Marmion RA, Park JO, Biswas D, Rabinowitz JD, Shvartsman SY. Dynamic Control of dNTP Synthesis in Early Embryos. Developmental Cell. PMID 28735680 DOI: 10.1016/J.Devcel.2017.06.013 |
0.295 |
|
| 2021 |
Bartman CR, TeSlaa T, Rabinowitz JD. Quantitative flux analysis in mammals. Nature Metabolism. PMID 34211182 DOI: 10.1038/s42255-021-00419-2 |
0.295 |
|
| 2021 |
Bartman CR, TeSlaa T, Rabinowitz JD. Quantitative flux analysis in mammals. Nature Metabolism. PMID 34211182 DOI: 10.1038/s42255-021-00419-2 |
0.295 |
|
| 2020 |
Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, Li P, Christensen S, Nguyen R, Lin JX, Oh J, Du N, Veenbergen S, Fioravanti J, Ebina-Shibuya R, ... ... Rabinowitz JD, et al. Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32123114 DOI: 10.1073/Pnas.1920413117 |
0.294 |
|
| 2015 |
Fan J, Teng X, Liu L, Mattaini KR, Looper RE, Vander Heiden MG, Rabinowitz JD. Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate. Acs Chemical Biology. 10: 510-6. PMID 25406093 DOI: 10.1021/Cb500683C |
0.294 |
|
| 2018 |
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metabolism. PMID 30449684 DOI: 10.1016/J.Cmet.2018.10.013 |
0.291 |
|
| 2016 |
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, ... ... Rabinowitz JD, et al. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nature Medicine. PMID 26950361 DOI: 10.1038/Nm.4057 |
0.29 |
|
| 2018 |
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, ... Rabinowitz JD, et al. Author Correction: Autophagy maintains tumour growth through circulating arginine. Nature. PMID 30523330 DOI: 10.1038/S41586-018-0815-6 |
0.287 |
|
| 2019 |
Song Y, Park JO, Tanner L, Nagano Y, Rabinowitz JD, Shvartsman SY. Energy budget of Drosophila embryogenesis. Current Biology : Cb. 29: R566-R567. PMID 31211973 DOI: 10.1016/J.Cub.2019.05.025 |
0.287 |
|
| 2018 |
Hui S, Rabinowitz JD. An unexpected trigger for calorie burning in brown fat. Nature. 560: 38-39. PMID 30061641 DOI: 10.1038/D41586-018-05619-7 |
0.287 |
|
| 2021 |
Olszewski K, Barsotti A, Feng XJ, Momcilovic M, Liu KG, Kim JI, Morris K, Lamarque C, Gaffney J, Yu X, Patel JP, Rabinowitz JD, Shackelford DB, Poyurovsky MV. Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors. Cell Chemical Biology. PMID 34715056 DOI: 10.1016/j.chembiol.2021.10.007 |
0.287 |
|
| 2020 |
Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, et al. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. PMID 32906142 DOI: 10.1038/S41586-020-2741-7 |
0.286 |
|
| 2016 |
Rabinowitz JD, Coller HA. Partners in the Warburg effect. Elife. 5. PMID 27073176 DOI: 10.7554/Elife.15938 |
0.286 |
|
| 2013 |
Tchigvintsev A, Tchigvintsev D, Flick R, Popovic A, Dong A, Xu X, Brown G, Lu W, Wu H, Cui H, Dombrowski L, Joo JC, Beloglazova N, Min J, Savchenko A, ... ... Rabinowitz JD, et al. Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chemistry & Biology. 20: 1386-98. PMID 24210219 DOI: 10.1016/J.Chembiol.2013.09.011 |
0.284 |
|
| 2016 |
Koivunen P, Fell SM, Lu W, Rabinowitz JD, Kung AL, Schlisio S. The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth. Hypoxia (Auckland, N.Z.). 4: 15-27. PMID 27525289 DOI: 10.2147/Hp.S96366 |
0.283 |
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| 2023 |
Bornstein MR, Neinast MD, Zeng X, Chu Q, Axsom J, Thorsheim C, Li K, Blair MC, Rabinowitz JD, Arany Z. Comprehensive quantification of metabolic flux during acute cold stress in mice. Cell Metabolism. PMID 37802078 DOI: 10.1016/j.cmet.2023.09.002 |
0.283 |
|
| 2016 |
Frederick DW, Loro E, Liu L, Davila A, Chellappa K, Silverman IM, Quinn WJ, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, ... ... Rabinowitz JD, et al. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metabolism. 24: 269-282. PMID 27508874 DOI: 10.1016/J.Cmet.2016.07.005 |
0.283 |
|
| 2010 |
Kuchma SL, Ballok AE, Merritt JH, Hammond JH, Lu W, Rabinowitz JD, O'Toole GA. Cyclic-di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa: the pilY1 gene and its impact on surface-associated behaviors. Journal of Bacteriology. 192: 2950-64. PMID 20233936 DOI: 10.1128/Jb.01642-09 |
0.282 |
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| 2008 |
DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Biclustering of data matrices in systems biology via optimal re-ordering Computer Aided Chemical Engineering. 25: 569-574. DOI: 10.1016/S1570-7946(08)80100-9 |
0.282 |
|
| 2009 |
Olszewski KL, Morrisey JM, Wilinski D, Burns JM, Vaidya AB, Rabinowitz JD, Llinás M. Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell Host & Microbe. 5: 191-9. PMID 19218089 DOI: 10.1016/J.Chom.2009.01.004 |
0.279 |
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| 2020 |
Xu Y, Zhang Y, García-Cañaveras JC, Guo L, Kan M, Yu S, Blair IA, Rabinowitz JD, Yang X. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science (New York, N.Y.). 369: 397-403. PMID 32703873 DOI: 10.1126/Science.Abb4467 |
0.279 |
|
| 2006 |
Kimball E, Rabinowitz JD. Identifying decomposition products in extracts of cellular metabolites. Analytical Biochemistry. 358: 273-80. PMID 16962982 DOI: 10.1016/J.Ab.2006.07.038 |
0.278 |
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| 2021 |
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, ... ... Rabinowitz JD, et al. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metabolism. PMID 33887198 DOI: 10.1016/j.cmet.2021.03.025 |
0.278 |
|
| 2007 |
Xavier KB, Miller ST, Lu W, Kim JH, Rabinowitz J, Pelczer I, Semmelhack MF, Bassler BL. Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria. Acs Chemical Biology. 2: 128-36. PMID 17274596 DOI: 10.1021/Cb600444H |
0.277 |
|
| 2018 |
Xu YF, Lu W, Chen JC, Johnson SA, Gibney PA, Thomas DG, Brown G, May AL, Campagna SR, Yakunin AF, Botstein D, Rabinowitz JD. Discovery and functional characterization of a yeast sugar alcohol phosphatase. Acs Chemical Biology. PMID 30240188 DOI: 10.1021/Acschembio.8B00804 |
0.276 |
|
| 2019 |
Benson KK, Hu W, Weller AH, Bennett AH, Chen ER, Khetarpal SA, Yoshino S, Bone WP, Wang L, Rabinowitz JD, Voight BF, Soccio RE. Natural human genetic variation determines basal and inducible expression of , an obesity-associated gene. Proceedings of the National Academy of Sciences of the United States of America. PMID 31659023 DOI: 10.1073/Pnas.1913199116 |
0.275 |
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| 2023 |
Lu W, Park NR, TeSlaa T, Jankowski CSR, Samarah L, McReynolds M, Xing X, Schembri J, Woolf MT, Rabinowitz JD, Davidson SM. Acidic Methanol Treatment Facilitates Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging of Energy Metabolism. Analytical Chemistry. 95: 14879-14888. PMID 37756255 DOI: 10.1021/acs.analchem.3c01875 |
0.274 |
|
| 2007 |
Bao Q, Lu W, Rabinowitz JD, Shi Y. Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1. Molecular Cell. 25: 181-92. PMID 17244527 DOI: 10.1016/J.Molcel.2006.12.013 |
0.272 |
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| 2008 |
Waters CM, Lu W, Rabinowitz JD, Bassler BL. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. Journal of Bacteriology. 190: 2527-36. PMID 18223081 DOI: 10.1128/Jb.01756-07 |
0.268 |
|
| 2017 |
Henrickson SE, Manne S, Herati RS, Vella LA, Bengsch B, Hensley SE, Rabinowitz JD, Coffin S, Wherry EJ. Metabolic and Deep Immune Profiling Reveal Coordinate Effects on Immune Function in Asthma and Obesity Journal of Allergy and Clinical Immunology. 139: AB197. DOI: 10.1016/J.Jaci.2016.12.638 |
0.267 |
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| 2020 |
Martin JK, Sheehan JP, Bratton BP, Moore GM, Mateus A, Li SH, Kim H, Rabinowitz JD, Typas A, Savitski MM, Wilson MZ, Gitai Z. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. PMID 32497502 DOI: 10.1016/J.Cell.2020.05.005 |
0.266 |
|
| 2019 |
Rabinowitz JD, Mutlu GM. A metabolic strategy to reverse fibrosis? Nature Metabolism. 1: 12-13. PMID 32694811 DOI: 10.1038/s42255-018-0013-8 |
0.266 |
|
| 2006 |
Minhas PS, Liu L, Moon PK, Mhatre SD, Wang Q, Coronado M, Contrepois K, Joshi AU, Dove CG, Kvalheim G, Midttun O, Majeti R, Bernstein D, Mochly-Rosen D, Snyder M, ... Rabinowitz J, et al. O4-02-05: DE NOVO NAD+ SYNTHESIS RESCUES NEUROINFLAMMATION AND ALZHEIMER'S DISEASE PHENOTYPES: MODULATING IMMUNE CELL RESPONSES AND MITOCHONDRIAL BIOENERGETICS Alzheimer's & Dementia. 14: P1403-P1404. DOI: 10.1016/J.Jalz.2018.06.2919 |
0.265 |
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| 2020 |
Zhang Y, Xu Y, Lu W, Ghergurovich JM, Guo L, Blair IA, Rabinowitz JD, Yang X. Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation. Cell Metabolism. PMID 33159852 DOI: 10.1016/j.cmet.2020.10.002 |
0.262 |
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| 2020 |
Rabinowitz JD, Enerbäck S. Lactate: the ugly duckling of energy metabolism. Nature Metabolism. 2: 566-571. PMID 32694798 DOI: 10.1038/s42255-020-0243-4 |
0.262 |
|
| 2019 |
Jameson GS, Borazanci EH, Rabinowitz J, Ansaldo K, LeGrand S, Propper D, Snyder C, Gordon M, Roe D, Hoff DDV. Abstract B27: A phase Ib/II trial of high-dose (HD) ascorbic acid (AA) + paclitaxel protein bound (PP) + cisplatin (C) + gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (MPC) Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B27 |
0.259 |
|
| 2012 |
Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen H, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Cell death induced by autophagy and mTOR inhibition is RIPK-dependent necroptosis. Plos One. DOI: 10.1371/Journal.Pone.0041831.G003 |
0.259 |
|
| 2011 |
Liu ST, Sharon-Friling R, Ivanova P, Milne SB, Myers DS, Rabinowitz JD, Brown HA, Shenk T. Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress. Proceedings of the National Academy of Sciences of the United States of America. 108: 12869-74. PMID 21768361 DOI: 10.1073/Pnas.1109796108 |
0.257 |
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| 2020 |
Parkhitko AA, Ramesh D, Wang L, Leshchiner D, Filine E, Binari R, Olsen AL, Asara JM, Cracan V, Rabinowitz JD, Brockmann A, Perrimon N. Downregulation of the tyrosine degradation pathway extends lifespan. Elife. 9. PMID 33319750 DOI: 10.7554/eLife.58053 |
0.251 |
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| 2016 |
Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, ... Rabinowitz JD, et al. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nature Medicine. PMID 27991918 DOI: 10.1038/Nm.4245 |
0.251 |
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| 2023 |
McBride MJ, Hunter CJ, Rabinowitz JD. Glycine homeostasis requires reverse SHMT flux. Biorxiv : the Preprint Server For Biology. PMID 36711816 DOI: 10.1101/2023.01.11.523668 |
0.249 |
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| 2016 |
Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metabolism. PMID 27238637 DOI: 10.1016/J.Cmet.2016.04.022 |
0.247 |
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| 2014 |
Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Corrigendum: Quantitative flux analysis reveals folate-dependent NADPH production Nature. 513: 574. DOI: 10.1038/Nature13675 |
0.245 |
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| 2023 |
Zhang Z, TeSlaa T, Rabinowitz JD. Reply to: revisiting the role of serine metabolism in hepatic lipogenesis. Nature Metabolism. 5: 762-764. PMID 37169877 DOI: 10.1038/s42255-023-00793-z |
0.244 |
|
| 2018 |
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nature Medicine. PMID 29895835 DOI: 10.1038/S41591-018-0047-1 |
0.244 |
|
| 2008 |
DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies. Bmc Bioinformatics. 9: 458. PMID 18954459 DOI: 10.1186/1471-2105-9-458 |
0.244 |
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| 2020 |
Suthers PF, Dinh HV, Fatma Z, Shen Y, Chan SHJ, Rabinowitz JD, Zhao H, Maranas CD. Genome-scale metabolic reconstruction of the non-model yeast SD108 and its application to organic acids production. Metabolic Engineering Communications. 11: e00148. PMID 33134082 DOI: 10.1016/j.mec.2020.e00148 |
0.243 |
|
| 2018 |
Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA. Author response: Nicotinamide adenine dinucleotide is transported into mammalian mitochondria Elife. DOI: 10.7554/Elife.33246.020 |
0.241 |
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| 2022 |
Meyer CF, Seath CP, Knutson SD, Lu W, Rabinowitz JD, MacMillan DWC. Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. Journal of the American Chemical Society. 144: 23633-23641. PMID 36525649 DOI: 10.1021/jacs.2c11094 |
0.24 |
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| 2017 |
Wooldridge AL, Bischof RJ, Liu H, Heinemann GK, Hunter DS, Giles LC, Simmons RA, Lien YC, Lu W, Rabinowitz JD, Kind KL, Owens JA, Clifton VL, Gatford KL. Late gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00549.2016. PMID 28978515 DOI: 10.1152/Ajpregu.00549.2016 |
0.238 |
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| 2023 |
TeSlaa T, Ralser M, Fan J, Rabinowitz JD. The pentose phosphate pathway in health and disease. Nature Metabolism. 5: 1275-1289. PMID 37612403 DOI: 10.1038/s42255-023-00863-2 |
0.238 |
|
| 2010 |
DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Li G, Rabinowitz JD, Rabitz HA. Enhancing molecular discovery using descriptor-free rearrangement clustering techniques for sparse data sets Aiche Journal. 56: 405-418. DOI: 10.1002/Aic.11986 |
0.235 |
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| 2020 |
Wilke AC, Doebele C, Zindel A, Lee KS, Rieke SA, Ceribelli M, Comoglio F, Phelan JD, Wang JQ, Pikman Y, Jahn D, Häupl B, Schneider C, Scheich S, Tosto FA, ... ... Rabinowitz JD, et al. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. PMID 34624079 DOI: 10.1182/blood.2021012081 |
0.234 |
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| 2008 |
McAllister SR, Feng XJ, DiMaggio PA, Floudas CA, Rabinowitz JD, Rabitz H. Descriptor-free molecular discovery in large libraries by adaptive substituent reordering. Bioorganic & Medicinal Chemistry Letters. 18: 5967-70. PMID 18851908 DOI: 10.1016/J.Bmcl.2008.09.068 |
0.232 |
|
| 1992 |
Petros W, Rabinowitz J, Stuart A, Gilbert C, Kanakura Y, Griffin J, Peters W. Disposition of recombinant human granulocyte-macrophage colony-stimulating factor in patients receiving high-dose chemotherapy and autologous bone marrow support. Blood. 80: 1135-1140. DOI: 10.1182/Blood.V80.5.1135.1135 |
0.23 |
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| 2022 |
Flam E, Jang C, Murashige D, Yang Y, Morley MP, Jung S, Kantner DS, Pepper H, Bedi KC, Brandimarto J, Prosser BL, Cappola T, Snyder NW, Rabinowitz JD, Margulies KB, et al. Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy. Nature Cardiovascular Research. 1: 817-829. PMID 36776621 DOI: 10.1038/s44161-022-00117-6 |
0.23 |
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| 2019 |
Liu Q, Johnson EM, Lam RK, Wang Q, Bo Ye H, Wilson EN, Minhas PS, Liu L, Swarovski MS, Tran S, Wang J, Mehta SS, Yang X, Rabinowitz JD, Yang SS, et al. Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity. Nature Immunology. PMID 31263278 DOI: 10.1038/S41590-019-0421-2 |
0.229 |
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| 2007 |
Cui H, Hayashi A, Sun HS, Belmares MP, Cobey C, Phan T, Schweizer J, Salter MW, Wang YT, Tasker RA, Garman D, Rabinowitz J, Lu PS, Tymianski M. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9901-15. PMID 17855605 DOI: 10.1523/Jneurosci.1464-07.2007 |
0.228 |
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| 2019 |
Benson K, Hu W, Weller A, Bennett A, Chen E, Kheterpal S, Yoshino S, Wang L, Rabinowitz J, Voight B, Lazar M, Soccio R. MON-LB017 Natural Genetic Variation in Humans Determines Basal and PPAR-Inducible Expression of PM20D1, a Putative Thermogenic Gene Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-Lb017 |
0.227 |
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| 2007 |
Avram MJ, Henthorn TK, Spyker DA, Krejcie TC, Lloyd PM, Cassella JV, Rabinowitz JD. Recirculatory pharmacokinetic model of the uptake, distribution, and bioavailability of prochlorperazine administered as a thermally generated aerosol in a single breath to dogs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 262-7. PMID 17079359 DOI: 10.1124/Dmd.106.010652 |
0.226 |
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| 2008 |
Dimaggio PA, Mcallister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Optimal methods for re-ordering data matrices in systems biology and drug discovery applications Biophysical Reviews and Letters. 3: 19-42. DOI: 10.1142/S1793048008000605 |
0.222 |
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| 2019 |
Murashige DS, Jang C, Neinast MD, Elrod JW, Kelly DP, Rabinowitz JD, Frankel DS, Arany ZP. Abstract 562: Comprehensive Arteriovenous Metabolomics in the Human Heart Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.562 |
0.22 |
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| 2021 |
Garcia-Canaveras JC, Heo D, Trefely S, Leferovich J, Xu C, Philipson BI, Ghassemi S, Milone MC, Moon EK, Snyder NW, June CH, Rabinowitz JD, O'Connor RS. CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production. Cells. 10. PMID 34571983 DOI: 10.3390/cells10092334 |
0.217 |
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| 2021 |
Ghergurovich JM, Lang JD, Levin MK, Briones N, Facista SJ, Mueller C, Cowan AJ, McBride MJ, Rodriguez ESR, Killian A, Dao T, Lamont J, Barron A, Su X, Hendricks WPD, ... ... Rabinowitz JD, et al. Local production of lactate, ribose phosphate, and amino acids within human triple-negative breast cancer. Med (New York, N.Y.). 2: 736-754. PMID 34223403 DOI: 10.1016/j.medj.2021.03.009 |
0.214 |
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| 2021 |
Ghergurovich JM, Lang JD, Levin MK, Briones N, Facista SJ, Mueller C, Cowan AJ, McBride MJ, Rodriguez ESR, Killian A, Dao T, Lamont J, Barron A, Su X, Hendricks WPD, ... ... Rabinowitz JD, et al. Local production of lactate, ribose phosphate, and amino acids within human triple-negative breast cancer. Med (New York, N.Y.). 2: 736-754. PMID 34223403 DOI: 10.1016/j.medj.2021.03.009 |
0.214 |
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| 2010 |
Dimaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. A network flow model for biclustering via optimal re-ordering of data matrices Journal of Global Optimization. 47: 343-354. DOI: 10.1007/S10898-008-9349-Z |
0.214 |
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| 2021 |
Schild T, McReynolds MR, Shea C, Low V, Schaffer BE, Asara JM, Piskounova E, Dephoure N, Rabinowitz JD, Gomes AP, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Reports. 35: 109238. PMID 34133937 DOI: 10.1016/j.celrep.2021.109238 |
0.213 |
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| 2021 |
Schild T, McReynolds MR, Shea C, Low V, Schaffer BE, Asara JM, Piskounova E, Dephoure N, Rabinowitz JD, Gomes AP, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Reports. 35: 109238. PMID 34133937 DOI: 10.1016/j.celrep.2021.109238 |
0.213 |
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| 2024 |
Uehara K, Lee WD, Stefkovich M, Biswas D, Santoleri D, Garcia Whitlock AE, Quinn Iii WJ, Coopersmith TN, Creasy KT, Rader DJ, Sakamoto K, Rabinowitz JD, Titchenell PM. mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b. The Journal of Clinical Investigation. PMID 38290087 DOI: 10.1172/JCI173782 |
0.213 |
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| 2004 |
Rabinowitz JD, Wensley M, Lloyd P, Myers D, Shen W, Lu A, Hodges C, Hale R, Mufson D, Zaffaroni A. Fast onset medications through thermally generated aerosols. The Journal of Pharmacology and Experimental Therapeutics. 309: 769-75. PMID 14752061 DOI: 10.1124/Jpet.103.062893 |
0.21 |
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| 2007 |
Myers DJ, Timmons RD, Lu AT, Hale RL, Solas DW, Soni P, Rabinowitz JD. The effect of film thickness on thermal aerosol generation. Pharmaceutical Research. 24: 336-42. PMID 17180726 DOI: 10.1007/S11095-006-9153-8 |
0.207 |
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| 2006 |
Rabinowitz JD, Lloyd PM, Munzar P, Myers DJ, Cross S, Damani R, Quintana R, Spyker DA, Soni P, Cassella JV. Ultra-fast absorption of amorphous pure drug aerosols via deep lung inhalation. Journal of Pharmaceutical Sciences. 95: 2438-51. PMID 16886198 DOI: 10.1002/Jps.20694 |
0.206 |
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| 2004 |
Turner-Cobb JM, Koopman C, Rabinowitz JD, Terr AI, Sephton SE, Spiegel D. The interaction of social network size and stressful life events predict delayed-type hypersensitivity among women with metastatic breast cancer. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. 54: 241-9. PMID 15331215 DOI: 10.1016/J.Ijpsycho.2004.05.010 |
0.206 |
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| 2023 |
Lee WD, Liang L, AbuSalim J, Jankowski CSR, Samarah LZ, Neinast MD, Rabinowitz JD. Impact of acute stress on murine metabolomics and metabolic flux. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301215120. PMID 37186827 DOI: 10.1073/pnas.2301215120 |
0.203 |
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| 2023 |
Xu X, Chen Z, Bartman CR, Xing X, Olszewski K, Rabinowitz JD. One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade. Biorxiv : the Preprint Server For Biology. PMID 37961420 DOI: 10.1101/2023.11.01.565193 |
0.201 |
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| 2022 |
Jankowski CSR, Rabinowitz JD. Selenium modulates cancer cell response to pharmacologic ascorbate. Cancer Research. PMID 35916672 DOI: 10.1158/0008-5472.CAN-22-0408 |
0.198 |
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| 2024 |
Bowman CE, Neinast MD, Jang C, Patel J, Blair MC, Mirek ET, Jonsson WO, Chu Q, Merlo L, Mandik-Nayak L, Anthony TG, Rabinowitz JD, Arany Z. Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK. Biorxiv : the Preprint Server For Biology. PMID 38496495 DOI: 10.1101/2024.03.05.582974 |
0.198 |
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| 2021 |
Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Molecular Cell. PMID 33756105 DOI: 10.1016/j.molcel.2021.03.010 |
0.196 |
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| 2022 |
Green CL, Pak HH, Richardson NE, Flores V, Yu D, Tomasiewicz JL, Dumas SN, Kredell K, Fan JW, Kirsh C, Chaiyakul K, Murphy ME, Babygirija R, Barrett-Wilt GA, Rabinowitz J, et al. Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction. Cell Metabolism. 34: 209-226.e5. PMID 35108511 DOI: 10.1016/j.cmet.2021.12.018 |
0.193 |
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| 2023 |
Rowe JH, Elia I, Shahid O, Gaudiano EF, Sifnugel NE, Johnson S, Reynolds AG, Fung ME, Joshi S, LaFleur MW, Park JS, Pauken KE, Rabinowitz JD, Freeman GJ, Haigis MC, et al. Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade. Cancer Discovery. PMID 37728660 DOI: 10.1158/2159-8290.CD-22-1301 |
0.193 |
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| 2022 |
Xiao T, Khan A, Shen Y, Chen L, Rabinowitz JD. Glucose feeds the tricarboxylic acid cycle via excreted ethanol in fermenting yeast. Nature Chemical Biology. PMID 35970997 DOI: 10.1038/s41589-022-01091-7 |
0.19 |
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| 2020 |
Henrickson S, O'Boyle K, Conrey P, Manne S, Bengsch B, Mentch F, Herati R, Qian T, Vella L, Pastore C, Hung L, Sayed S, Herbert D, Masino A, Hensley S, ... ... Rabinowitz J, et al. Mechanisms by which Obesity Dysregulates Immunometabolic State in Asthma Journal of Allergy and Clinical Immunology. 145: AB157. DOI: 10.1016/J.Jaci.2019.12.410 |
0.189 |
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| 2022 |
Zhang Y, Xu Y, Lu W, Li J, Yu S, Brown EJ, Stanger BZ, Rabinowitz JD, Yang X. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Science Advances. 8: eabo0404. PMID 35857842 DOI: 10.1126/sciadv.abo0404 |
0.187 |
|
| 1997 |
Elkordy M, Crump M, Vredenburgh JJ, Petros WP, Hussein A, Rubin P, Ross M, Gilbert C, Modlin C, Meisenberg B, Coniglio D, Rabinowitz J, Laughlin M, Kurtzberg J, Peters WP. A phase I trial of recombinant human interleukin-1 beta (OCT-43) following high-dose chemotherapy and autologous bone marrow transplantation. Bone Marrow Transplantation. 19: 315-22. PMID 9051240 DOI: 10.1038/Sj.Bmt.1700633 |
0.185 |
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| 2021 |
Li SH, Nofal M, Parsons LR, Rabinowitz JD, Gitai Z. Monitoring mammalian mitochondrial translation with MitoRiboSeq. Nature Protocols. PMID 33953394 DOI: 10.1038/s41596-021-00517-1 |
0.185 |
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| 2021 |
TeSlaa T, Bartman CR, Jankowski CSR, Zhang Z, Xu X, Xing X, Wang L, Lu W, Hui S, Rabinowitz JD. The Source of Glycolytic Intermediates in Mammalian Tissues. Cell Metabolism. PMID 33472024 DOI: 10.1016/j.cmet.2020.12.020 |
0.182 |
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| 2020 |
Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao CH, Yoon H, Sage PT, LaFleur MW, Trombley JD, ... ... Rabinowitz JD, et al. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. PMID 33301708 DOI: 10.1016/j.cell.2020.11.009 |
0.177 |
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| 2023 |
Hu M, Dinh HV, Shen Y, Suthers PF, Foster CJ, Call CM, Ye X, Pratas J, Fatma Z, Zhao H, Rabinowitz JD, Maranas CD. Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale. Metabolic Engineering. PMID 36603705 DOI: 10.1016/j.ymben.2023.01.001 |
0.176 |
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| 2023 |
Wu ZY, Sun W, Shen Y, Pratas J, Suthers PF, Hsieh PH, Dwaraknath S, Rabinowitz JD, Maranas CD, Shao Z, Yoshikuni Y. Metabolic engineering of low-pH-tolerant non-model yeast, , for production of citramalate. Metabolic Engineering Communications. 16: e00220. PMID 36860699 DOI: 10.1016/j.mec.2023.e00220 |
0.171 |
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| 2023 |
Lan T, Arastu S, Wang S, Lam J, Wang W, Bhatt V, Lopes EC, Hu Z, Sun M, Luo X, Ghergurovich JM, Li C, Su X, Rabinowitz JD, White E, et al. G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer. Biorxiv : the Preprint Server For Biology. PMID 37873106 DOI: 10.1101/2023.10.06.561131 |
0.168 |
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| 2008 |
Feng X, Rabinowitz J, Rabitz H. Development of laboratory and computational techniques for optimal and quantitative understanding of cellular metabolic networks Ipdps Miami 2008 - Proceedings of the 22nd Ieee International Parallel and Distributed Processing Symposium, Program and Cd-Rom. DOI: 10.1109/IPDPS.2008.4536416 |
0.166 |
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| 2023 |
Kafri M, Patena W, Martin L, Wang L, Gomer G, Ergun SL, Sirkejyan AK, Goh A, Wilson AT, Gavrilenko SE, Breker M, Roichman A, McWhite CD, Rabinowitz JD, Cross FR, et al. Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery. Cell. 186: 5638-5655.e25. PMID 38065083 DOI: 10.1016/j.cell.2023.11.007 |
0.161 |
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| 2021 |
McReynolds MR, Chellappa K, Chiles E, Jankowski C, Shen Y, Chen L, Descamps HC, Mukherjee S, Bhat YR, Lingala SR, Chu Q, Botolin P, Hayat F, Doke T, Susztak K, ... ... Rabinowitz JD, et al. NAD flux is maintained in aged mice despite lower tissue concentrations. Cell Systems. PMID 34559996 DOI: 10.1016/j.cels.2021.09.001 |
0.16 |
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| 2023 |
Zhang KR, Jankowski CSR, Marshall R, Nair R, Gómez NM, Alnemri A, Liu Y, Erler E, Ferrante J, Song Y, Bell BA, Baumann BH, Sterling J, Anderson B, Foshe S, ... ... Rabinowitz JD, et al. Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells. Disease Models & Mechanisms. PMID 37401371 DOI: 10.1242/dmm.050066 |
0.158 |
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| 2020 |
Luongo T, Wang L, Chellappa K, McReynolds MR, Kelly DP, Rabinowitz JD, Baur JA. 4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE Journal of Clinical and Translational Science. 4: 13-13. DOI: 10.1017/cts.2020.83 |
0.156 |
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| 2020 |
Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Sherrie Hu Z, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, et al. Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nature Cancer. 1: 923-934. PMID 34476408 DOI: 10.1038/s43018-020-00110-7 |
0.155 |
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| 2021 |
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, Joshi AU, He JQ, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon PK, Majeti R, ... ... Rabinowitz JD, et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. PMID 33473210 DOI: 10.1038/s41586-020-03160-0 |
0.147 |
|
| 2020 |
Xu G, van Bruggen R, Gualtieri CO, Moradin N, Fois A, Vallerand D, De Sa Tavares Russo M, Bassenden A, Lu W, Tam M, Lesage S, Girouard H, Avizonis DZ, Deblois G, Prchal JT, ... ... Rabinowitz J, et al. Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia. Cell Reports. 32: 108170. PMID 32966787 DOI: 10.1016/j.celrep.2020.108170 |
0.142 |
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| 2024 |
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, ... ... Rabinowitz JD, et al. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models. Nature Neuroscience. PMID 38539014 DOI: 10.1038/s41593-024-01610-w |
0.135 |
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| 2023 |
Zhang X, Lee WD, Leitner BP, Zhu W, Fosam A, Li Z, Gaspar RC, Halberstam AA, Robles B, Rabinowitz JD, Perry RJ. Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma. American Journal of Physiology. Endocrinology and Metabolism. PMID 37646579 DOI: 10.1152/ajpendo.00105.2023 |
0.132 |
|
| 2020 |
Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science (New York, N.Y.). 370: 364-368. PMID 33060364 DOI: 10.1126/science.abc8861 |
0.132 |
|
| 2023 |
Tran VG, Mishra S, Bhagwat SS, Shafaei S, Shen Y, Allen JL, Crosly BA, Tan SI, Fatma Z, Rabinowitz JD, Guest JS, Singh V, Zhao H. An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis. Nature Communications. 14: 6152. PMID 37788990 DOI: 10.1038/s41467-023-41616-9 |
0.121 |
|
| 2020 |
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, ... ... Rabinowitz JD, et al. CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD and NMN levels. Nature Metabolism. 2: 1284-1304. PMID 33199925 DOI: 10.1038/s42255-020-00298-z |
0.12 |
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| 2024 |
Chain C, Sheehan JP, Xu X, Ghaffari S, Godbole A, Kim H, Freundlich JS, Rabinowitz JD, Gitai Z. A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting. Nature Microbiology. PMID 38594311 DOI: 10.1038/s41564-024-01665-2 |
0.12 |
|
| 2022 |
Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, et al. Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nature Cancer. 2: 994. PMID 35121870 DOI: 10.1038/s43018-021-00252-2 |
0.116 |
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| 2023 |
Culbertson B, Garcia K, Markett D, Asgharian H, Chen L, Fish L, Navickas A, Yu J, Woo B, Nanda AS, Choi B, Zhou S, Rabinowitz J, Goodarzi H. A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression. Nature Cancer. PMID 37169843 DOI: 10.1038/s43018-023-00554-7 |
0.111 |
|
| 2017 |
Lin KC, Torga G, Wu A, Rabinowitz JD, Murray WJ, Sturm JC, Pienta KJ, Austin R. Epithelial and mesenchymal prostate cancer cell population dynamics on a complex drug landscape. Convergent Science Physical Oncology. 3. PMID 29527324 DOI: 10.1088/2057-1739/AA83BF |
0.108 |
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| 2023 |
Blair MC, Neinast MD, Jang C, Chu Q, Jung JW, Axsom J, Bornstein MR, Thorsheim C, Li K, Hoshino A, Yang S, Roth Flach RJ, Zhang BB, Rabinowitz JD, Arany Z. Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance. Nature Metabolism. 5: 589-606. PMID 37100997 DOI: 10.1038/s42255-023-00794-y |
0.103 |
|
| 1993 |
Rabinowitz J, Petros W, Stuart A, Peters W. Characterization of endogenous cytokine concentrations after high-dose chemotherapy with autologous bone marrow support Blood. 81: 2452-2459. DOI: 10.1182/blood.v81.9.2452.2452 |
0.081 |
|
| 2024 |
Tran VG, Mishra S, Bhagwat SS, Shafaei S, Shen Y, Allen JL, Crosly BA, Tan SI, Fatma Z, Rabinowitz JD, Guest JS, Singh V, Zhao H. Author Correction: An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis. Nature Communications. 15: 1161. PMID 38326306 DOI: 10.1038/s41467-024-45331-x |
0.076 |
|
| 2022 |
Lindell RB, Zhang D, Bush J, Wallace DC, Rabinowitz JD, Lu W, Wherry EJ, Weiss SL, Henrickson SE. Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation. Shock (Augusta, Ga.). 57: 191-199. PMID 35759301 DOI: 10.1097/SHK.0000000000001943 |
0.075 |
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| 2022 |
Murashige D, Jung JW, Neinast MD, Levin MG, Chu Q, Lambert JP, Garbincius JF, Kim B, Hoshino A, Marti-Pamies I, McDaid KS, Shewale SV, Flam E, Yang S, Roberts E, ... ... Rabinowitz JD, et al. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metabolism. PMID 36223763 DOI: 10.1016/j.cmet.2022.09.008 |
0.073 |
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| 2008 |
DIMAGGIO PA, MCALLISTER SR, FLOUDAS CA, FENG X, RABINOWITZ JD, RABITZ HA. OPTIMAL METHODS FOR RE-ORDERING DATA MATRICES IN SYSTEMS BIOLOGY AND DRUG DISCOVERY APPLICATIONS Biophysical Reviews and Letters. 3: 19-42. DOI: 10.1142/S1793048008000605 |
0.067 |
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| 2021 |
Ding H, Chen Z, Wu K, Huang SM, Wu WL, LeBoeuf SE, Pillai RG, Rabinowitz JD, Papagiannakopoulos T. Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition. Science Advances. 7: eabk1023. PMID 34788087 DOI: 10.1126/sciadv.abk1023 |
0.06 |
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| 2023 |
Chan K, Hampson A, Hayes J, Rabinowitz J, Vasdev N. Blue light transurethral resection and biopsy of bladder cancer with hexaminolevulinate: Histopathological characteristics and recurrence rates in a single UK centre study. Bjui Compass. 4: 568-574. PMID 37636209 DOI: 10.1002/bco2.250 |
0.05 |
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| 2024 |
Ibrahim M, Rabinowitz J, Hilbert R, Ghose A, Agarwal S, Swamy R, Bulut I, Guttierrez M, Buali E, Nassar E, Jhavar P, Al-Hashimi F, Vasdev N. The role of URO17® in diagnosis and follow up of bladder cancer patients. Bmc Urology. 24: 34. PMID 38336681 DOI: 10.1186/s12894-024-01426-7 |
0.047 |
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| 2024 |
Rabinowitz J, Kinnear N, O'Callaghan M, Hennessey D, Shafi F, Fuller A, Ibrahim M, Lane T, Adshead J, Vasdev N. Systematic review of the ophthalmic complications of robotic-assisted laparoscopic prostatectomy. Journal of Robotic Surgery. 18: 46. PMID 38240959 DOI: 10.1007/s11701-023-01771-z |
0.037 |
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| 2022 |
Rabinowitz J, Perin G, Balasubramanian SP. Operative Autonomy of Surgical Residents and Patient Outcomes. Jama Surgery. PMID 35353133 DOI: 10.1001/jamasurg.2022.0304 |
0.01 |
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