Paul Martin Thomas - Publications

2009 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gerbasi VR, Melani RD, Abbatiello SE, Belford MW, Huguet R, McGee JP, Dayhoff D, Thomas PM, Kelleher NL. Deeper Protein Identification Using Field Asymmetric Ion Mobility Spectrometry in Top-Down Proteomics. Analytical Chemistry. PMID 33844503 DOI: 10.1021/acs.analchem.1c00402  0.92
2021 Liu Y, Davis RG, Thomas PM, Kelleher NL, Jewett MC. -Constructed Ribosomes Enable Multi-site Incorporation of Noncanonical Amino Acids into Proteins. Biochemistry. PMID 33426883 DOI: 10.1021/acs.biochem.0c00829  0.92
2020 Parsa S, Ortega-Molina A, Ying HY, Jiang M, Teater M, Wang J, Zhao C, Reznik E, Pasion JP, Kuo D, Mohan P, Wang S, Camarillo JM, Thomas PM, Jain N, et al. The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. Nature Cancer. 1: 653-664. PMID 33569544 DOI: 10.1038/s43018-020-0080-0  0.92
2020 Fornelli L, Srzentić K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, ... Thomas PM, et al. Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics. Molecular & Cellular Proteomics : McP. 19: 405-420. PMID 33451396 DOI: 10.1074/mcp.TIR119.001638  0.92
2020 An S, Camarillo JM, Huang TY, Li D, Morris JA, Zoltek MA, Qi J, Behbahani M, Kambhampati M, Kelleher NL, Nazarian J, Thomas PM, Saratsis AM. Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma. Journal of Experimental & Clinical Cancer Research : Cr. 39: 261. PMID 33239043 DOI: 10.1186/s13046-020-01773-x  0.92
2020 Abshiru NA, Sikora JW, Camarillo JM, Morris JA, Compton PD, Lee T, Neelamraju Y, Haddox S, Sheridan C, Carroll M, Cripe LD, Tallman MS, Paietta EM, Melnick AM, Thomas PM, et al. Targeted detection and quantitation of histone modifications from 1,000 cells. Plos One. 15: e0240829. PMID 33104722 DOI: 10.1371/journal.pone.0240829  0.92
2020 Deighan WI, Winton VJ, Melani RD, Anderson LC, McGee JP, Schachner LF, Barnidge D, Murray D, Alexander HD, Gibson DS, Deery MJ, McNicholl FP, McLaughlin J, Kelleher NL, Thomas PM. Development of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and middle-down de novo sequencing. Clinical Chemistry and Laboratory Medicine. PMID 33079696 DOI: 10.1515/cclm-2020-1072  0.92
2020 Caesar LK, Robey MT, Swyers M, Islam MN, Ye R, Vagadia PP, Schiltz GE, Thomas PM, Wu CC, Kelleher NL, Keller NP, Bok JW. Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds. Mbio. 11. PMID 32843555 DOI: 10.1128/Mbio.01691-20  0.92
2020 Kosciuk T, Price IR, Zhang X, Zhu C, Johnson KN, Zhang S, Halaby SL, Komaniecki GP, Yang M, DeHart CJ, Thomas PM, Kelleher NL, Christopher Fromme J, Lin H. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications. 11: 1067. PMID 32103017 DOI: 10.1038/S41467-020-14893-X  0.92
2020 Winer B, Edgel KA, Zou X, Sellau J, Hadiwidjojo S, Garver LS, McDonough CE, Kelleher NL, Thomas PM, Villasante E, Ploss A, Gerbasi VR. Identification of Plasmodium falciparum proteoforms from liver stage models. Malaria Journal. 19: 10. PMID 31910830 DOI: 10.1186/S12936-019-3093-3  0.92
2019 LeDuc RD, Fellers RT, Early BP, Greer JB, Shams DP, Thomas PM, Kelleher NL. Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics. Molecular & Cellular Proteomics : McP. 18: 796-805. PMID 33451659 DOI: 10.1074/mcp.RA118.000993  0.92
2019 Fornelli L, Srzentić K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, ... Thomas P, et al. Thorough performance evaluation of 213 nm ultraviolet photodissociation for top-down proteomics. Molecular & Cellular Proteomics : McP. PMID 31888965 DOI: 10.1074/Mcp.Tir119.001638  0.92
2019 Des Soye BJ, Gerbasi VR, Thomas PM, Kelleher NL, Jewett MC. A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli. Cell Chemical Biology. PMID 31706984 DOI: 10.1016/J.Chembiol.2019.10.008  0.92
2019 Park HM, Satta R, Davis RG, Goo YA, LeDuc RD, Fellers RT, Greer JB, Romanova EV, Rubakhin SS, Tai R, Thomas PM, Sweedler JV, Kelleher NL, Patrie SM, Lasek AW. Multidimensional Top-Down Proteomics of Brain Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol. Journal of Proteome Research. PMID 31550894 DOI: 10.1021/Acs.Jproteome.9B00481  0.92
2019 Smith LM, Thomas PM, Shortreed MR, Schaffer LV, Fellers RT, LeDuc RD, Tucholski T, Ge Y, Agar JN, Anderson LC, Chamot-Rooke J, Gault J, Loo JA, Paša-Tolić L, Robinson CV, et al. A five-level classification system for proteoform identifications. Nature Methods. PMID 31451767 DOI: 10.1038/S41592-019-0573-X  0.92
2019 Camarillo JM, Swaminathan S, Abshiru NA, Sikora JW, Thomas PM, Kelleher NL. Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes. Journal of the American Society For Mass Spectrometry. PMID 31286445 DOI: 10.1007/S13361-019-02255-X  0.92
2019 Ro SY, Schachner LF, Koo CW, Purohit R, Remis JP, Kenney GE, Liauw BW, Thomas PM, Patrie SM, Kelleher NL, Rosenzweig AC. Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase. Nature Communications. 10: 2675. PMID 31209220 DOI: 10.1038/S41467-019-10590-6  0.92
2019 Schaffer LV, Millikin RJ, Miller RM, Anderson LC, Fellers RT, Ge Y, Kelleher NL, LeDuc RD, Liu X, Payne SH, Sun L, Thomas PM, Tucholski T, Wang Z, Wu S, et al. Identification and Quantification of Proteoforms by Mass Spectrometry. Proteomics. e1800361. PMID 31050378 DOI: 10.1002/Pmic.201800361  0.92
2019 Zhang Z, Qiu L, Yan S, Wang JJ, Thomas PM, Kandpal M, Zhao L, Iovane A, Liu XF, Thorp EB, Chen Q, Hummel M, Kanwar YS, Abecassis MM. A clinically relevant murine model unmasks a 'Two-Hit' mechanism for reactivation and dissemination of cytomegalovirus following kidney transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30947382 DOI: 10.1111/Ajt.15376  0.8
2019 LeDuc RD, Fellers RT, Early BP, Greer JB, Shams DP, Thomas P, Kelleher NL. Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics. Molecular & Cellular Proteomics : McP. PMID 30647073 DOI: 10.1074/Mcp.Ra118.000993  0.92
2018 Fisher OS, Kenney GE, Ross MO, Ro SY, Lemma BE, Batelu S, Thomas PM, Sosnowski VC, DeHart CJ, Kelleher NL, Stemmler TL, Hoffman BM, Rosenzweig AC. Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nature Communications. 9: 4276. PMID 30323281 DOI: 10.2210/Pdb6Cpd/Pdb  0.92
2018 Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutiérrez-Díaz BT, Wang KK, Johnson MR, Volk A, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, et al. USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T cell leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30224337 DOI: 10.1158/1078-0432.Ccr-18-1740  0.92
2018 Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA. Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells. Plos One. 13: e0203351. PMID 30192817 DOI: 10.1371/Journal.Pone.0203351  0.92
2018 Riley NM, Sikora JW, Seckler HS, Greer JB, Fellers RT, LeDuc RD, Westphall MS, Thomas PM, Kelleher NL, Coon JJ. The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins. Analytical Chemistry. PMID 29924586 DOI: 10.1021/Acs.Analchem.8B01638  0.92
2018 Alvares K, DeHart CJ, Thomas PM, Kelleher NL, Veis A. The unique biomineralization transcriptome and proteome of Lytechinus variegatus teeth. Connective Tissue Research. 59: 20-29. PMID 29745816 DOI: 10.1080/03008207.2017.1408605  0.92
2018 Robey MT, Ye R, Bok JW, Clevenger KD, Islam MN, Chen C, Gupta R, Swyers M, Wu E, Gao P, Thomas PM, Wu CC, Keller NP, Kelleher NL. Identification of the First Diketomorpholine Biosynthetic Pathway Using FAC-MS Technology. Acs Chemical Biology. PMID 29631395 DOI: 10.1021/Acschembio.8B00024  0.92
2018 Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Ranji Charna AK, Patel JR, Isaacs FJ, et al. Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids. Nature Communications. 9: 1203. PMID 29572528 DOI: 10.1038/S41467-018-03469-5  0.92
2018 Kenney GE, Dassama LMK, Pandelia ME, Gizzi AS, Martinie RJ, Gao P, DeHart CJ, Schachner LF, Skinner OS, Ro SY, Zhu X, Sadek M, Thomas PM, Almo SC, Bollinger JM, et al. The biosynthesis of methanobactin. Science (New York, N.Y.). 359: 1411-1416. PMID 29567715 DOI: 10.1126/Science.Aap9437  0.92
2018 Clevenger KD, Ye R, Bok JW, Thomas PM, Islam MN, Miley GP, Robey M, Chen C, Yang K, Swyers M, Wu E, Gao P, Wu C, Keller NP, Kelleher NL. Interrogation of Benzomalvin Biosynthesis using FAC-MS: Discovery of a Benzodiazepine Synthase Activity. Biochemistry. PMID 29533658 DOI: 10.1021/Acs.Biochem.8B00076  0.92
2018 Davis RG, Park HM, Kim K, Greer JB, Fellers RT, LeDuc RD, Romanova EV, Rubakhin SS, Zombeck JA, Wu C, Yau PM, Gao P, van Nispen AJ, Patrie SM, Thomas PM, et al. Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains. Analytical Chemistry. PMID 29481055 DOI: 10.1021/Acs.Analchem.7B04108  0.92
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, ... ... Thomas PM, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576  0.92
2017 Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou HJ, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müeller CW, Kelleher NL, et al. A synthetic biology approach to probing nucleosome symmetry. Elife. 6. PMID 28895528 DOI: 10.7554/Elife.28836  0.92
2017 Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL. Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. Scientific Reports. 7: 9520. PMID 28842697 DOI: 10.1038/S41598-017-10422-X  0.92
2017 Clevenger KD, Bok JW, Ye R, Miley GP, Verdan MH, Velk T, Chen C, Yang K, Robey MT, Gao P, Lamprecht M, Thomas PM, Islam MN, Palmer JM, Wu CC, et al. A scalable platform to identify fungal secondary metabolites and their gene clusters. Nature Chemical Biology. PMID 28604695 DOI: 10.1038/Nchembio.2408  0.92
2017 Toby TK, Abecassis M, Kim K, Thomas PM, Fellers RT, LeDuc RD, Kelleher NL, Demetris J, Levitsky J. Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28510335 DOI: 10.1111/Ajt.14359  0.92
2017 Cleland TP, DeHart CJ, Fellers RT, VanNispen AJ, Greer JB, LeDuc RD, Parker WR, Thomas PM, Kelleher NL, Brodbelt JS. High-throughput analysis of intact human proteins using UVPD and HCD on an Orbitrap mass spectrometer. Journal of Proteome Research. PMID 28412815 DOI: 10.1021/Acs.Jproteome.7B00043  0.92
2017 DeHart CJ, Fellers RT, Fornelli L, Kelleher NL, Thomas PM. Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite. Methods in Molecular Biology (Clifton, N.J.). 1558: 381-394. PMID 28150248 DOI: 10.1007/978-1-4939-6783-4_18  0.92
2017 Schroeter ER, DeHart CJ, Cleland TP, Zheng W, Thomas PM, Kelleher NL, Bern M, Schweitzer MH. Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein. Journal of Proteome Research. PMID 28111950 DOI: 10.1021/Acs.Jproteome.6B00873  0.92
2017 Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou H, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müller CW, Kelleher NL, et al. Author response: A synthetic biology approach to probing nucleosome symmetry Elife. DOI: 10.7554/Elife.28836.019  0.92
2016 Clevenger KD, Bok JW, Ye R, Miley GP, Velk T, Chen C, Yang K, Gao P, Lamprecht M, Thomas PM, Islam MN, Wu CC, Keller NP, Kelleher NL. Large scale discovery and deorphanization of natural products using fungal artificial chromosomes and untargeted metabolomics (FAC-MS). Planta Medica. 81: S1-S381. PMID 27976333 DOI: 10.1055/S-0036-1596148  0.92
2016 Anderson LC, DeHart CJ, Kaiser NK, Fellers RT, Smith DF, Greer JB, LeDuc RD, Blakney GT, Thomas PM, Kelleher NL, Hendrickson CL. Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry. Journal of Proteome Research. PMID 27936753 DOI: 10.1021/Acs.Jproteome.6B00696  0.92
2016 Schroeter ER, DeHart CJ, Schweitzer MH, Thomas PM, Kelleher NL. Bone protein "extractomics": comparing the efficiency of bone protein extractions of Gallus gallus in tandem mass spectrometry, with an eye towards paleoproteomics. Peerj. 4: e2603. PMID 27812413 DOI: 10.7717/Peerj.2603  0.92
2016 Kenney GE, Goering AW, Ross MO, DeHart CJ, Thomas PM, Hoffman BM, Kelleher NL, Rosenzweig AC. Characterization of methanobactin from Methylosinus sp. LW4. Journal of the American Chemical Society. PMID 27527063 DOI: 10.1021/Jacs.6B06821  0.92
2016 LaFave LM, Béguelin W, Koche R, Teater M, Spitzer B, Chramiec A, Papalexi E, Keller MD, Hricik T, Konstantinoff K, Micol JB, Durham B, Knutson SK, Campbell JE, Blum G, ... ... Thomas PM, et al. Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status". Nature Medicine. 22: 578-579. PMID 27270773 DOI: 10.1038/Nm.4094  0.92
2016 Savaryn JP, Toby TK, Catherman AD, Fellers RT, LeDuc RD, Thomas PM, Friedewald JJ, Salomon DR, Abecassis MM, Kelleher NL. Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection. Proteomics. PMID 27120713 DOI: 10.1002/Pmic.201600008  0.92
2015 Kim K, Compton PD, Toby TK, Thomas PM, Wilkins JT, Mutharasan RK, Kelleher NL. Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics. Eupa Open Proteomics. 8: 40-47. PMID 26753126 DOI: 10.1016/J.Euprot.2015.05.005  0.92
2015 Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. PMID 26595531 DOI: 10.1021/Acs.Jproteome.5B00675  0.92
2015 Rodrigues Lorenzatto K, Kim K, Ntai I, Prado Paludo G, Camargo de Lima J, Thomas PM, Kelleher NL, Ferreira HB. Top down proteomics reveals mature proteoforms expressed in subcellular fractions of the Echinococcus granulosus pre-adult stage. Journal of Proteome Research. PMID 26465659 DOI: 10.1021/Acs.Jproteome.5B00642  0.92
2015 LaFave LM, Béguelin W, Koche R, Teater M, Spitzer B, Chramiec A, Papalexi E, Keller MD, Hricik T, Konstantinoff K, Micol JB, Durham B, Knutson SK, Campbell JE, Blum G, ... ... Thomas PM, et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nature Medicine. PMID 26437366 DOI: 10.1038/Nm.3947  0.92
2015 Ye H, Wang J, Zhang Z, Jia C, Schmerberg CM, Catherman AD, Thomas PM, Kelleher NL, Li L. Defining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multi-Dimensional Mass Spectrometry-Based Platform. Journal of Proteome Research. PMID 26390183 DOI: 10.1021/Acs.Jproteome.5B00627  0.92
2015 Zheng Y, Fornelli L, Compton PD, Sharma S, Canterbury J, Mullen C, Zabrouskov V, Fellers RT, Thomas PM, Licht JD, Senko MW, Kelleher NL. Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression. Molecular & Cellular Proteomics : McP. PMID 26272979 DOI: 10.1074/Mcp.M115.053819  0.92
2015 Bok JW, Ye R, Clevenger KD, Mead D, Wagner M, Krerowicz A, Albright JC, Goering AW, Thomas PM, Kelleher NL, Keller NP, Wu CC. Fungal artificial chromosomes for mining of the fungal secondary metabolome. Bmc Genomics. 16: 343. PMID 25925221 DOI: 10.1186/S12864-015-1561-X  0.92
2015 Fellers RT, Greer JB, Early BP, Yu X, LeDuc RD, Kelleher NL, Thomas PM. ProSight Lite: graphical software to analyze top-down mass spectrometry data. Proteomics. 15: 1235-8. PMID 25828799 DOI: 10.1002/Pmic.201400313  0.92
2015 Kim K, Compton PD, Toby TK, Thomas PM, Wilkins JT, Mutharasan RK, Kelleher NL. Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics Eupa Open Proteomics. DOI: 10.1016/j.euprot.2015.05.005  0.92
2014 Fellers RT, Greer JB, Early BP, Yu X, LeDuc RD, Kelleher NL, Thomas PM. ProSight Lite: Graphical software to analyze top-down mass spectrometry data. Proteomics. PMID 25504941 DOI: 10.1002/pmic.201400313  0.92
2014 Kelleher NL, Thomas PM, Ntai I, Compton PD, LeDuc RD. Deep and quantitative top-down proteomics in clinical and translational research. Expert Review of Proteomics. 11: 649-51. PMID 25347991 DOI: 10.1586/14789450.2014.976559  0.92
2014 LeDuc RD, Fellers RT, Early BP, Greer JB, Thomas PM, Kelleher NL. The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics. Journal of Proteome Research. 13: 3231-40. PMID 24922115 DOI: 10.1021/Pr401277R  0.92
2014 Zheng Y, Tipton JD, Thomas PM, Kelleher NL, Sweet SM. Site-specific human histone H3 methylation stability: fast K4me3 turnover. Proteomics. 14: 2190-9. PMID 24826939 DOI: 10.1002/Pmic.201400060  0.92
2014 Ntai I, Kim K, Fellers RT, Skinner OS, Smith AD, Early BP, Savaryn JP, LeDuc RD, Thomas PM, Kelleher NL. Applying label-free quantitation to top down proteomics. Analytical Chemistry. 86: 4961-8. PMID 24807621 DOI: 10.1021/Ac500395K  0.92
2014 Ye H, Mandal R, Catherman A, Thomas PM, Kelleher NL, Ikonomidou C, Li L. Top-down proteomics with mass spectrometry imaging: a pilot study towards discovery of biomarkers for neurodevelopmental disorders. Plos One. 9: e92831. PMID 24710523 DOI: 10.1371/Journal.Pone.0092831  0.92
2014 Skinner OS, Catherman AD, Early BP, Thomas PM, Compton PD, Kelleher NL. Fragmentation of integral membrane proteins in the gas phase. Analytical Chemistry. 86: 4627-34. PMID 24689519 DOI: 10.1021/Ac500864W  0.92
2014 Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, et al. The first pilot project of the consortium for top-down proteomics: a status report. Proteomics. 14: 1130-40. PMID 24644084 DOI: 10.1002/Pmic.201300438  0.92
2014 Cannon JR, Cammarata MB, Robotham SA, Cotham VC, Shaw JB, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS. Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale. Analytical Chemistry. 86: 2185-92. PMID 24447299 DOI: 10.1021/Ac403859A  0.92
2013 Catherman AD, Durbin KR, Ahlf DR, Early BP, Fellers RT, Tran JC, Thomas PM, Kelleher NL. Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence. Molecular & Cellular Proteomics : McP. 12: 3465-73. PMID 24023390 DOI: 10.1074/Mcp.M113.030114  0.92
2013 Ahlf DR, Thomas PM, Kelleher NL. Developing top down proteomics to maximize proteome and sequence coverage from cells and tissues. Current Opinion in Chemical Biology. 17: 787-94. PMID 23988518 DOI: 10.1016/J.Cbpa.2013.07.028  0.92
2013 Zheng Y, Thomas PM, Kelleher NL. Measurement of acetylation turnover at distinct lysines in human histones identifies long-lived acetylation sites. Nature Communications. 4: 2203. PMID 23892279 DOI: 10.1038/Ncomms3203  0.92
2013 Savaryn JP, Catherman AD, Thomas PM, Abecassis MM, Kelleher NL. The emergence of top-down proteomics in clinical research. Genome Medicine. 5: 53. PMID 23806018 DOI: 10.1186/Gm457  0.92
2013 Shaw JB, Li W, Holden DD, Zhang Y, Griep-Raming J, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS. Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. Journal of the American Chemical Society. 135: 12646-51. PMID 23697802 DOI: 10.1021/Ja4029654  0.92
2013 Catherman AD, Li M, Tran JC, Durbin KR, Compton PD, Early BP, Thomas PM, Kelleher NL. Top down proteomics of human membrane proteins from enriched mitochondrial fractions. Analytical Chemistry. 85: 1880-8. PMID 23305238 DOI: 10.1021/Ac3031527  0.92
2012 Park S, Ntai I, Thomas P, Konishcheva E, Kelleher NL, Statsuk AV. Mechanism-based small molecule cross-linkers of HECT E3 ubiquitin ligase-substrate pairs. Biochemistry. 51: 8327-9. PMID 23043241 DOI: 10.1021/Bi301231H  0.92
2012 Jia C, Hui L, Cao W, Lietz CB, Jiang X, Chen R, Catherman AD, Thomas PM, Ge Y, Kelleher NL, Li L. High-definition de novo sequencing of crustacean hyperglycemic hormone (CHH)-family neuropeptides. Molecular & Cellular Proteomics : McP. 11: 1951-64. PMID 23028060 DOI: 10.1074/Mcp.M112.020537  0.92
2012 Fornelli L, Damoc E, Thomas PM, Kelleher NL, Aizikov K, Denisov E, Makarov A, Tsybin YO. Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS. Molecular & Cellular Proteomics : McP. 11: 1758-67. PMID 22964222 DOI: 10.1074/Mcp.M112.019620  0.92
2012 Zheng Y, Sweet SM, Popovic R, Martinez-Garcia E, Tipton JD, Thomas PM, Licht JD, Kelleher NL. Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3. Proceedings of the National Academy of Sciences of the United States of America. 109: 13549-54. PMID 22869745 DOI: 10.1073/Pnas.1205707109  0.92
2012 Ahlf DR, Compton PD, Tran JC, Early BP, Thomas PM, Kelleher NL. Evaluation of the compact high-field orbitrap for top-down proteomics of human cells. Journal of Proteome Research. 11: 4308-14. PMID 22746247 DOI: 10.1021/Pr3004216  0.92
2012 Wu C, Tran JC, Zamdborg L, Durbin KR, Li M, Ahlf DR, Early BP, Thomas PM, Sweedler JV, Kelleher NL. A protease for 'middle-down' proteomics. Nature Methods. 9: 822-4. PMID 22706673 DOI: 10.1038/Nmeth.2074  0.92
2012 Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE, Thomas PM, Kelleher NL. Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry. Analytical Chemistry. 84: 209-15. PMID 22103811 DOI: 10.1021/Ac202384V  0.92
2011 Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, ... ... Thomas PM, et al. Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature. 480: 254-8. PMID 22037311 DOI: 10.1038/Nature10575  0.92
2011 Compton PD, Zamdborg L, Thomas PM, Kelleher NL. On the scalability and requirements of whole protein mass spectrometry. Analytical Chemistry. 83: 6868-74. PMID 21744800 DOI: 10.1021/Ac2010795  0.92
2011 Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood. 117: 211-20. PMID 20974671 DOI: 10.1182/Blood-2010-07-298349  0.92
2010 Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, Kelleher NL. The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput. Molecular Biosystems. 6: 1532-9. PMID 20711533 DOI: 10.1039/C000896F  0.92
2010 Sweet SM, Li M, Thomas PM, Durbin KR, Kelleher NL. Kinetics of re-establishing H3K79 methylation marks in global human chromatin. The Journal of Biological Chemistry. 285: 32778-86. PMID 20699226 DOI: 10.1074/Jbc.M110.145094  0.92
2010 Johannes TW, DeSieno MA, Griffin BM, Thomas PM, Kelleher NL, Metcalf WW, Zhao H. Deciphering the late biosynthetic steps of antimalarial compound FR-900098. Chemistry & Biology. 17: 57-64. PMID 20142041 DOI: 10.1016/J.Chembiol.2009.12.009  0.92
2010 Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, Kelleher NL. Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa. Analytical Chemistry. 82: 1234-44. PMID 20073486 DOI: 10.1021/Ac9021083  0.92
2009 Bumpus SB, Evans BS, Thomas PM, Ntai I, Kelleher NL. A proteomics approach to discovering natural products and their biosynthetic pathways. Nature Biotechnology. 27: 951-6. PMID 19767731 DOI: 10.1038/Nbt.1565  0.92
2009 Kalaitzis JA, Cheng Q, Thomas PM, Kelleher NL, Moore BS. In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides. Journal of Natural Products. 72: 469-72. PMID 19215142 DOI: 10.1021/Np800598T  0.92
2008 Eliot AC, Griffin BM, Thomas PM, Johannes TW, Kelleher NL, Zhao H, Metcalf WW. Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. Chemistry & Biology. 15: 765-70. PMID 18721747 DOI: 10.1016/J.Chembiol.2008.07.010  0.92
2008 Magarvey NA, Fortin PD, Thomas PM, Kelleher NL, Walsh CT. Gatekeeping versus promiscuity in the early stages of the andrimid biosynthetic assembly line. Acs Chemical Biology. 3: 542-54. PMID 18652473 DOI: 10.1021/Cb800085G  0.92
2008 Crawford JM, Thomas PM, Scheerer JR, Vagstad AL, Kelleher NL, Townsend CA. Deconstruction of iterative multidomain polyketide synthase function. Science (New York, N.Y.). 320: 243-6. PMID 18403714 DOI: 10.1126/Science.1154711  0.92
2007 Whitteck JT, Ni W, Griffin BM, Eliot AC, Thomas PM, Kelleher NL, Metcalf WW, van der Donk WA. Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid. Angewandte Chemie (International Ed. in English). 46: 9089-92. PMID 17990255 DOI: 10.1002/Anie.200703810  0.92
2007 Parks BA, Jiang L, Thomas PM, Wenger CD, Roth MJ, Boyne MT, Burke PV, Kwast KE, Kelleher NL. Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers. Analytical Chemistry. 79: 7984-91. PMID 17915963 DOI: 10.1021/Ac070553T  0.92
2007 Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW. Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nature Chemical Biology. 3: 480-5. PMID 17632514 DOI: 10.1038/Nchembio.2007.9  0.92
2006 Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H. Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. Chemistry & Biology. 13: 1171-82. PMID 17113999 DOI: 10.1016/J.Chembiol.2006.09.007  0.92
2006 McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA. Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proceedings of the National Academy of Sciences of the United States of America. 103: 17243-8. PMID 17085596 DOI: 10.1073/Pnas.0606088103  0.92
2005 Thomas PM, Foster GD. Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process. Environmental Toxicology and Chemistry / Setac. 24: 25-30. PMID 15683164 DOI: 10.1897/04-144R.1  0.92
2004 Thomas PM, Foster GD. Determination of nonsteroidal anti-inflammatory drugs, caffeine, and triclosan in wastewater by gas chromatography-mass spectrometry. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 39: 1969-78. PMID 15332662 DOI: 10.1081/Ese-120039368  0.92
2003 Thomas PM, Flanagan VP, Pawlosky RJ. Determination of 5-methyltetrahydrofolic acid and folic acid in citrus juices using stable isotope dilution-mass spectrometry. Journal of Agricultural and Food Chemistry. 51: 1293-6. PMID 12590471 DOI: 10.1021/Jf020902E  0.92
2003 Pawlosky RJ, Hertrampf E, Flanagan VP, Thomas PM. Mass spectral determinations of the folic acid content of fortified breads from Chile Journal of Food Composition and Analysis. 16: 281-286. DOI: 10.1016/S0889-1575(03)00033-4  0.92
2002 Flanagan VP, Thomas PM, Pawlosky RJ. Measurement of oxidized 5-methyltetrahydrofolic acid in human plasma: A potential biological marker of in vivo oxidation Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 551-552.  0.92
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